locus-tag	class	description
FDF35_00065	COG2009	succinate dehydrogenase
FDF35_00240	COG0589	response to stress
FDF35_00250	COG0251	oxidation-reduction process
FDF35_00255	COG1309	transcriptional regulator
FDF35_00270	COG0505	Belongs to the CarA family
FDF35_00295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF35_00300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDF35_00350	COG0477	Major facilitator Superfamily
FDF35_00355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDF35_00375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF35_00400	COG0584	glycerophosphoryl diester phosphodiesterase
FDF35_00445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDF35_00460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF35_00485	COG0778	Nitroreductase
FDF35_00500	COG1929	Belongs to the glycerate kinase type-1 family
FDF35_00505	COG0243	molybdopterin cofactor binding
FDF35_00510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDF35_00515	COG3339	Conserved Protein
FDF35_00525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDF35_00540	COG1115	amino acid carrier protein
FDF35_00545	COG1113	amino acid transport
FDF35_00555	COG0019	diaminopimelate decarboxylase activity
FDF35_00565	COG2267	carboxylic ester hydrolase activity
FDF35_00570	COG1280	lysine exporter protein (LysE YggA)
FDF35_00575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDF35_00605	COG0463	Glycosyl transferase, family 2
FDF35_00625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_00655	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDF35_00660	COG1136	(ABC) transporter
FDF35_00665	COG0658	competence protein
FDF35_00665	COG2333	competence protein COMEC
FDF35_00675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDF35_00675	COG0616	signal peptide processing
FDF35_00680	COG0596	Alpha beta hydrolase
FDF35_00685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDF35_00695	COG0628	permease
FDF35_00730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF35_00750	COG0823	Involved in the tonB-independent uptake of proteins
FDF35_00770	COG0824	Thioesterase
FDF35_00795	COG0047	phosphoribosylformylglycinamidine synthase activity
FDF35_00795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDF35_00800	COG2814	Major facilitator Superfamily
FDF35_00805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDF35_00810	COG1024	Enoyl-CoA hydratase
FDF35_00825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDF35_00840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDF35_00855	COG4625	pathogenesis
FDF35_00860	COG0583	DNA-binding transcription factor activity
FDF35_00865	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDF35_00870	COG4208	sulfate ABC transporter
FDF35_00875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDF35_00885	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FDF35_00890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDF35_00895	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDF35_00915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF35_00930	COG0681	Belongs to the peptidase S26 family
FDF35_00945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDF35_00955	COG1381	Involved in DNA repair and RecF pathway recombination
FDF35_00960	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDF35_00970	COG4221	oxidoreductase activity
FDF35_01000	COG0443	Heat shock 70 kDa protein
FDF35_01030	COG0556	nucleotide-excision repair
FDF35_01115	COG1215	transferase activity, transferring glycosyl groups
FDF35_01130	COG0415	Belongs to the DNA photolyase family
FDF35_01140	COG1252	NADH dehydrogenase
FDF35_01145	COG1686	Belongs to the peptidase S11 family
FDF35_01160	COG1187	pseudouridine synthase activity
FDF35_01220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDF35_01405	COG0582	viral genome integration into host DNA
FDF35_01435	COG0477	Major facilitator Superfamily
FDF35_01440	COG0583	DNA-binding transcription factor activity
FDF35_01455	COG0612	Peptidase, M16
FDF35_01480	COG0352	thiamine-phosphate diphosphorylase activity
FDF35_01515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF35_01540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF35_01545	COG0076	glutamate decarboxylase activity
FDF35_01555	COG1522	sequence-specific DNA binding
FDF35_01560	COG3961	Belongs to the TPP enzyme family
FDF35_01565	COG1113	amino acid transport
FDF35_01570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDF35_01575	COG0573	inorganic phosphate transmembrane transporter activity
FDF35_01585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDF35_01590	COG0616	signal peptide processing
FDF35_01625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDF35_01630	COG1686	Belongs to the peptidase S11 family
FDF35_01655	COG0583	DNA-binding transcription factor activity
FDF35_01660	COG1067	ATP-dependent peptidase activity
FDF35_01705	COG1966	Carbon starvation protein
FDF35_01710	COG2879	small protein
FDF35_01745	COG1741	Belongs to the pirin family
FDF35_01760	COG2964	Protein conserved in bacteria
FDF35_01780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDF35_01785	COG4605	iron ion homeostasis
FDF35_01790	COG4604	ABC transporter, ATP-binding protein
FDF35_01795	COG4607	ABC-type enterochelin transport system periplasmic component
FDF35_01800	COG4774	siderophore transport
FDF35_01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF35_01815	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDF35_01845	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FDF35_01855	COG1169	isochorismate synthase
FDF35_01870	COG3739	integral membrane protein
FDF35_01945	COG0512	Glutamine amidotransferase of anthranilate synthase
FDF35_01955	COG3104	oligopeptide transport
FDF35_01970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDF35_02005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDF35_02010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDF35_02015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF35_02035	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDF35_02045	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDF35_02060	COG1960	acyl-CoA dehydrogenase activity
FDF35_02065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF35_02070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF35_02080	COG2223	nitrite transmembrane transporter activity
FDF35_02090	COG0024	Methionine aminopeptidase
FDF35_02095	COG0052	Belongs to the universal ribosomal protein uS2 family
FDF35_02110	COG2207	Transcriptional regulator
FDF35_02140	COG0772	Belongs to the SEDS family
FDF35_02155	COG0842	Transport permease protein
FDF35_02160	COG1131	(ABC) transporter
FDF35_02195	COG1538	Outer membrane efflux protein
FDF35_02205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_02220	COG4215	(ABC) transporter
FDF35_02225	COG4160	amino acid transport
FDF35_02230	COG4598	ABC transporter
FDF35_02240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF35_02265	COG1720	tRNA m6t6A37 methyltransferase activity
FDF35_02285	COG0745	RESPONSE REGULATOR receiver
FDF35_02290	COG0642	Histidine kinase
FDF35_02300	COG0494	nUDIX hydrolase
FDF35_02310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDF35_02315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDF35_02320	COG3139	Protein of unknown function (DUF1315)
FDF35_02335	COG1301	dicarboxylic acid transport
FDF35_02340	COG1960	acyl-CoA dehydrogenase activity
FDF35_02345	COG2819	hydrolase of the alpha beta superfamily
FDF35_02355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDF35_02365	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDF35_02385	COG1690	Belongs to the RtcB family
FDF35_02390	COG1234	tRNA 3'-trailer cleavage
FDF35_02395	COG4650	regulator
FDF35_02425	COG2363	Small membrane protein
FDF35_02445	COG0513	Belongs to the DEAD box helicase family
FDF35_02455	COG0778	Nitroreductase
FDF35_02485	COG1286	toxin biosynthetic process
FDF35_02510	COG4783	chaperone-mediated protein folding
FDF35_02515	COG1610	YqeY-like protein
FDF35_02520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDF35_02615	COG3111	PFAM Bacterial OB fold (BOF) protein
FDF35_02640	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDF35_02645	COG0786	glutamate:sodium symporter activity
FDF35_02655	COG2186	Transcriptional regulator
FDF35_02705	COG0477	Major facilitator Superfamily
FDF35_02735	COG2995	paraquat-inducible protein a
FDF35_02740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDF35_02740	COG3008	intermembrane lipid transfer
FDF35_02750	COG2351	hydroxyisourate hydrolase activity
FDF35_02800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDF35_02805	COG0642	Histidine kinase
FDF35_02810	COG0745	RESPONSE REGULATOR receiver
FDF35_02830	COG1794	racemase activity, acting on amino acids and derivatives
FDF35_02860	COG1301	dicarboxylic acid transport
FDF35_02870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF35_02875	COG2011	ABC-type metal ion transport system permease component
FDF35_02880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF35_02885	COG1464	Belongs to the NlpA lipoprotein family
FDF35_02895	COG0138	bifunctional purine biosynthesis protein purh
FDF35_02900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDF35_02930	COG2308	Evidence 4 Homologs of previously reported genes of
FDF35_02940	COG1305	Transglutaminase-like
FDF35_02955	COG0305	Participates in initiation and elongation during chromosome replication
FDF35_02980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDF35_02990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDF35_02995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDF35_03025	COG1215	transferase activity, transferring glycosyl groups
FDF35_03030	COG3658	cytochrome
FDF35_03040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF35_03060	COG0583	DNA-binding transcription factor activity
FDF35_03090	COG1960	acyl-CoA dehydrogenase activity
FDF35_03095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF35_03100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_03125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDF35_03130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDF35_03135	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FDF35_03140	COG2205	protein histidine kinase activity
FDF35_03145	COG0745	RESPONSE REGULATOR receiver
FDF35_03150	COG0174	glutamine synthetase
FDF35_03170	COG0729	surface antigen
FDF35_03200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF35_03205	COG2814	Major facilitator Superfamily
FDF35_03225	COG0583	DNA-binding transcription factor activity
FDF35_03240	COG1187	pseudouridine synthase activity
FDF35_03260	COG0802	atpase or kinase
FDF35_03265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDF35_03275	COG1923	regulation of RNA biosynthetic process
FDF35_03280	COG0697	spore germination
FDF35_03295	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF35_03310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF35_03310	COG0519	Catalyzes the synthesis of GMP from XMP
FDF35_03315	COG4302	ethanolamine ammonia-lyase activity
FDF35_03325	COG0531	amino acid
FDF35_03345	COG1454	alcohol dehydrogenase
FDF35_03350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDF35_03375	COG0308	aminopeptidase N
FDF35_03415	COG1605	Chorismate mutase
FDF35_03435	COG1309	transcriptional regulator
FDF35_03445	COG0668	transmembrane transport
FDF35_03475	COG4773	Receptor
FDF35_03495	COG0488	(ABC) transporter
FDF35_03500	COG0589	response to stress
FDF35_03530	COG1522	sequence-specific DNA binding
FDF35_03545	COG0583	DNA-binding transcription factor activity
FDF35_03555	COG0183	Belongs to the thiolase family
FDF35_03595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDF35_03605	COG0824	Thioesterase
FDF35_03610	COG1454	alcohol dehydrogenase
FDF35_03620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDF35_03650	COG0069	glutamate synthase activity
FDF35_03720	COG3620	sequence-specific DNA binding
FDF35_03820	COG5410	chromosome segregation
FDF35_03910	COG1598	PFAM Uncharacterised protein family UPF0150
FDF35_03970	COG3179	chitinase
FDF35_03980	COG1063	alcohol dehydrogenase
FDF35_03985	COG3293	Transposase
FDF35_04015	COG2814	Major facilitator Superfamily
FDF35_04030	COG0511	ligase activity, forming carbon-carbon bonds
FDF35_04050	COG0745	RESPONSE REGULATOR receiver
FDF35_04060	COG2146	nitrite reductase [NAD(P)H] activity
FDF35_04060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF35_04065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF35_04070	COG0243	molybdopterin cofactor binding
FDF35_04080	COG0243	molybdopterin cofactor binding
FDF35_04085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDF35_04100	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDF35_04100	COG0315	cyclic pyranopterin monophosphate synthase activity
FDF35_04105	COG0303	'Molybdopterin
FDF35_04115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF35_04120	COG0697	spore germination
FDF35_04140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDF35_04145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF35_04205	COG2204	response regulator
FDF35_04210	COG3852	Histidine kinase
FDF35_04235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDF35_04240	COG0575	Belongs to the CDS family
FDF35_04255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDF35_04275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF35_04290	COG2137	regulation of response to DNA damage stimulus
FDF35_04300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDF35_04305	COG1011	Hydrolase
FDF35_04340	COG1113	amino acid transport
FDF35_04355	COG0659	secondary active sulfate transmembrane transporter activity
FDF35_04360	COG2135	peptidase activity
FDF35_04375	COG3300	MHYT domain
FDF35_04375	COG5001	Diguanylate cyclase
FDF35_04390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDF35_04390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF35_04390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF35_04395	COG1105	Belongs to the carbohydrate kinase PfkB family
FDF35_04400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDF35_04400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF35_04430	COG0024	Methionine aminopeptidase
FDF35_04445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDF35_04450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF35_04455	COG0517	IMP dehydrogenase activity
FDF35_04455	COG0516	GMP reductase activity
FDF35_04480	COG0552	protein localization to endoplasmic reticulum
FDF35_04490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDF35_04505	COG4890	Cyd operon protein YbgT
FDF35_04510	COG1294	oxidase, subunit
FDF35_04530	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDF35_04540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDF35_04545	COG4774	siderophore transport
FDF35_04560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDF35_04565	COG0569	domain protein
FDF35_04570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDF35_04600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDF35_04605	COG0542	response to heat
FDF35_04615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDF35_04675	COG2323	membrane
FDF35_04680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDF35_04690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF35_04695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF35_04700	COG0183	Belongs to the thiolase family
FDF35_04705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDF35_04710	COG0596	Alpha beta hydrolase
FDF35_04715	COG2271	Major facilitator Superfamily
FDF35_04720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDF35_04725	COG3485	protocatechuate 3,4-dioxygenase
FDF35_04730	COG3485	protocatechuate 3,4-dioxygenase
FDF35_04740	COG3420	alginic acid biosynthetic process
FDF35_04745	COG3659	wide pore channel activity
FDF35_04750	COG4993	Dehydrogenase
FDF35_04760	COG2391	methyltransferase activity
FDF35_04775	COG1414	Transcriptional regulator
FDF35_04780	COG0583	DNA-binding transcription factor activity
FDF35_04785	COG1960	acyl-CoA dehydrogenase activity
FDF35_04810	COG2814	Major facilitator Superfamily
FDF35_04820	COG0154	amidase activity
FDF35_04840	COG4638	Rieske (2fe-2S)
FDF35_04850	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_04860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_04870	COG3733	amine oxidase
FDF35_04880	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_04890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF35_04895	COG0183	Belongs to the thiolase family
FDF35_04900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF35_04905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF35_04915	COG4829	muconolactone delta-isomerase
FDF35_04920	COG4948	Mandelate Racemase Muconate Lactonizing
FDF35_04925	COG0583	DNA-binding transcription factor activity
FDF35_04935	COG2186	Transcriptional regulator
FDF35_04955	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_04970	COG1902	pentaerythritol trinitrate reductase activity
FDF35_04970	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF35_05010	COG1309	transcriptional regulator
FDF35_05015	COG0583	DNA-binding transcription factor activity
FDF35_05020	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05025	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05030	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05040	COG1960	acyl-CoA dehydrogenase activity
FDF35_05130	COG0583	DNA-binding transcription factor activity
FDF35_05170	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_05175	COG0129	dihydroxy-acid dehydratase activity
FDF35_05190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDF35_05200	COG2084	Dehydrogenase
FDF35_05210	COG1064	alcohol dehydrogenase
FDF35_05245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDF35_05295	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDF35_05360	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05370	COG2207	Transcriptional regulator
FDF35_05385	COG2205	protein histidine kinase activity
FDF35_05390	COG0745	RESPONSE REGULATOR receiver
FDF35_05395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_05405	COG1538	Outer membrane efflux protein
FDF35_05415	COG2072	flavoprotein involved in K transport
FDF35_05435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDF35_05525	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDF35_05535	COG4149	molybdate abc transporter
FDF35_05540	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDF35_05550	COG4638	Rieske (2fe-2S)
FDF35_05555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF35_05560	COG0543	2 iron, 2 sulfur cluster binding
FDF35_05560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF35_05575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_05585	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05590	COG0412	Dienelactone hydrolase
FDF35_05605	COG2207	Transcriptional regulator
FDF35_05610	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_05625	COG0583	DNA-binding transcription factor activity
FDF35_05640	COG2031	fatty acid transporter
FDF35_05645	COG0183	Belongs to the thiolase family
FDF35_05650	COG0583	DNA-binding transcription factor activity
FDF35_05655	COG0583	DNA-binding transcription factor activity
FDF35_05670	COG1027	Aspartate ammonia-lyase
FDF35_05680	COG0477	Major facilitator Superfamily
FDF35_05700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF35_05705	COG4521	taurine ABC transporter
FDF35_05730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDF35_05735	COG1733	regulation of RNA biosynthetic process
FDF35_05740	COG2207	Transcriptional regulator
FDF35_05740	COG3708	Transcriptional regulator
FDF35_05755	COG0730	response to heat
FDF35_05765	COG3453	Protein conserved in bacteria
FDF35_05765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF35_05775	COG3781	membrane
FDF35_05780	COG1063	alcohol dehydrogenase
FDF35_05790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF35_05795	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF35_05800	COG0022	dehydrogenase e1 component
FDF35_05805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDF35_05810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF35_05825	COG3706	GGDEF domain
FDF35_05850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF35_05885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDF35_05910	COG2226	methyltransferase
FDF35_05965	COG0842	Transport permease protein
FDF35_05990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF35_05995	COG4773	Receptor
FDF35_06015	COG0730	response to heat
FDF35_06020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDF35_06035	COG0406	alpha-ribazole phosphatase activity
FDF35_06055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDF35_06090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF35_06100	COG4264	IucA IucC family
FDF35_06105	COG4264	IucA IucC family
FDF35_06110	COG2814	Major facilitator Superfamily
FDF35_06125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDF35_06140	COG1960	acyl-CoA dehydrogenase activity
FDF35_06145	COG1960	acyl-CoA dehydrogenase activity
FDF35_06150	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDF35_06155	COG2207	Transcriptional regulator
FDF35_06160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF35_06165	COG0776	regulation of translation
FDF35_06190	COG0822	iron-sulfur transferase activity
FDF35_06195	COG0316	Belongs to the HesB IscA family
FDF35_06225	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDF35_06245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF35_06250	COG0702	epimerase
FDF35_06285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDF35_06295	COG0339	signal peptide processing
FDF35_06345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDF35_06430	COG3646	Phage regulatory protein
FDF35_06545	COG0305	Participates in initiation and elongation during chromosome replication
FDF35_06615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDF35_06645	COG0776	regulation of translation
FDF35_06665	COG0590	tRNA wobble adenosine to inosine editing
FDF35_06695	COG2165	general secretion pathway protein
FDF35_06710	COG0084	hydrolase, TatD family'
FDF35_06745	COG0811	peptide transport
FDF35_06750	COG1475	DNA binding
FDF35_06755	COG1192	Involved in chromosome partitioning
FDF35_06765	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDF35_06780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF35_06785	COG0191	fructose-bisphosphate aldolase activity
FDF35_06805	COG0424	maF-like protein
FDF35_06810	COG2850	peptidyl-arginine hydroxylation
FDF35_06820	COG0640	Transcriptional regulator
FDF35_06830	COG3619	membrane
FDF35_06835	COG3122	Protein conserved in bacteria
FDF35_06840	COG1132	(ABC) transporter
FDF35_06860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDF35_06865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF35_06875	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF35_06875	COG0506	proline dehydrogenase activity
FDF35_06875	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF35_06880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDF35_06895	COG3698	Phosphodiester glycosidase
FDF35_06905	COG2353	YceI-like domain
FDF35_06915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDF35_06960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDF35_06960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDF35_06990	COG3121	Chaperone
FDF35_07020	COG0697	spore germination
FDF35_07030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDF35_07040	COG0583	DNA-binding transcription factor activity
FDF35_07060	COG1309	transcriptional regulator
FDF35_07075	COG1522	sequence-specific DNA binding
FDF35_07085	COG1126	abc transporter atp-binding protein
FDF35_07090	COG0765	amino acid transport
FDF35_07095	COG0765	amino acid transport
FDF35_07125	COG1464	Belongs to the NlpA lipoprotein family
FDF35_07135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF35_07140	COG2011	ABC-type metal ion transport system permease component
FDF35_07145	COG0012	GTP binding
FDF35_07170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDF35_07210	COG0386	Belongs to the glutathione peroxidase family
FDF35_07220	COG0436	Aminotransferase
FDF35_07260	COG3634	alkyl hydroperoxide reductase activity
FDF35_07275	COG0583	DNA-binding transcription factor activity
FDF35_07280	COG0431	NADPH-dependent FMN reductase
FDF35_07285	COG0798	PFAM Bile acid sodium symporter
FDF35_07295	COG0640	Transcriptional regulator
FDF35_07310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDF35_07320	COG0583	DNA-binding transcription factor activity
FDF35_07330	COG1953	Uracil, thiamine, allantoin
FDF35_07340	COG2175	clavaminate synthase activity
FDF35_07345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF35_07350	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDF35_07365	COG0477	Major facilitator Superfamily
FDF35_07390	COG1271	oxidase subunit
FDF35_07395	COG1294	oxidase, subunit
FDF35_07405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF35_07425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDF35_07445	COG3052	prosthetic group binding
FDF35_07450	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDF35_07470	COG2814	Major facilitator Superfamily
FDF35_07490	COG1346	cytolysis
FDF35_07500	COG0583	DNA-binding transcription factor activity
FDF35_07505	COG0625	glutathione transferase activity
FDF35_07515	COG0583	DNA-binding transcription factor activity
FDF35_07520	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_07530	COG1045	serine acetyltransferase
FDF35_07535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF35_07540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDF35_07545	COG1280	lysine exporter protein (LysE YggA)
FDF35_07555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF35_07560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF35_07565	COG1126	abc transporter atp-binding protein
FDF35_07570	COG0765	amino acid transport
FDF35_07575	COG0765	amino acid transport
FDF35_07620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDF35_07640	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_07690	COG0583	DNA-binding transcription factor activity
FDF35_07720	COG1309	transcriptional regulator
FDF35_07725	COG1960	acyl-CoA dehydrogenase activity
FDF35_07730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDF35_07735	COG1024	Enoyl-CoA hydratase
FDF35_07750	COG0583	DNA-binding transcription factor activity
FDF35_07765	COG1960	acyl-CoA dehydrogenase activity
FDF35_07775	COG2814	Major facilitator Superfamily
FDF35_07785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF35_07790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF35_07795	COG2814	Major facilitator Superfamily
FDF35_07800	COG1960	acyl-CoA dehydrogenase activity
FDF35_07805	COG1024	Enoyl-CoA hydratase
FDF35_07810	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_07815	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF35_07820	COG0183	Belongs to the thiolase family
FDF35_07830	COG2814	Major facilitator Superfamily
FDF35_07840	COG1024	Enoyl-CoA hydratase
FDF35_07855	COG1960	acyl-CoA dehydrogenase activity
FDF35_07860	COG2814	Major facilitator Superfamily
FDF35_07865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDF35_07870	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDF35_07885	COG3842	ATPase activity
FDF35_07905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF35_07920	COG0583	DNA-binding transcription factor activity
FDF35_07925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDF35_07940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDF35_07950	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_07955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF35_07960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_07965	COG2267	carboxylic ester hydrolase activity
FDF35_07985	COG3038	cytochrome b561
FDF35_07990	COG0753	catalase activity
FDF35_07995	COG2271	Major facilitator Superfamily
FDF35_08000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDF35_08005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDF35_08020	COG2207	Transcriptional regulator
FDF35_08030	COG1278	Cold shock
FDF35_08090	COG2050	protein possibly involved in aromatic compounds catabolism
FDF35_08100	COG3327	negative regulation of DNA-templated transcription, initiation
FDF35_08105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDF35_08110	COG0183	Belongs to the thiolase family
FDF35_08120	COG1024	Enoyl-CoA hydratase
FDF35_08125	COG1024	Enoyl-CoA hydratase
FDF35_08130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF35_08135	COG2151	metal-sulfur cluster biosynthetic enzyme
FDF35_08140	COG3396	Phenylacetate-CoA oxygenase
FDF35_08145	COG3460	Phenylacetate-CoA oxygenase
FDF35_08150	COG3396	Phenylacetate-CoA oxygenase
FDF35_08160	COG1760	l-serine dehydratase
FDF35_08165	COG0531	amino acid
FDF35_08170	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_08195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDF35_08215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF35_08230	COG0789	Transcriptional regulator
FDF35_08255	COG2807	transmembrane transport
FDF35_08260	COG0590	tRNA wobble adenosine to inosine editing
FDF35_08270	COG0583	DNA-binding transcription factor activity
FDF35_08310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDF35_08310	COG2885	chlorophyll binding
FDF35_08440	COG1116	anion transmembrane transporter activity
FDF35_08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF35_08455	COG0864	Transcriptional regulator
FDF35_08470	COG1733	regulation of RNA biosynthetic process
FDF35_08475	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF35_08495	COG1063	alcohol dehydrogenase
FDF35_08505	COG1309	transcriptional regulator
FDF35_08525	COG0038	chloride channel
FDF35_08530	COG4770	biotin carboxylase activity
FDF35_08550	COG1914	H( )-stimulated, divalent metal cation uptake system
FDF35_08555	COG0583	DNA-binding transcription factor activity
FDF35_08585	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF35_08605	COG2814	Major facilitator Superfamily
FDF35_08630	COG5006	permease, DMT superfamily
FDF35_08635	COG1522	sequence-specific DNA binding
FDF35_08650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDF35_08690	COG1538	Outer membrane efflux protein
FDF35_08695	COG1137	ATPase activity
FDF35_08700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDF35_08710	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDF35_08715	COG0517	IMP dehydrogenase activity
FDF35_08715	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDF35_08755	COG1733	regulation of RNA biosynthetic process
FDF35_08760	COG2814	Major facilitator Superfamily
FDF35_08800	COG1278	Cold shock
FDF35_08805	COG1280	lysine exporter protein (LysE YggA)
FDF35_08840	COG1570	exodeoxyribonuclease VII activity
FDF35_08900	COG4638	Rieske (2fe-2S)
FDF35_08905	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF35_08910	COG0633	Ferredoxin
FDF35_08910	COG0543	2 iron, 2 sulfur cluster binding
FDF35_08915	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_08920	COG3135	benzoate transporter
FDF35_08925	COG2814	Major facilitator Superfamily
FDF35_08945	COG0450	alkyl hydroperoxide reductase
FDF35_08955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDF35_08965	COG3634	alkyl hydroperoxide reductase activity
FDF35_09015	COG0625	glutathione transferase activity
FDF35_09025	COG2885	chlorophyll binding
FDF35_09075	COG1765	OsmC-like protein
FDF35_09085	COG0667	Aldo Keto reductase
FDF35_09100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDF35_09130	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDF35_09140	COG3038	cytochrome b561
FDF35_09145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDF35_09150	COG2252	PERMEase
FDF35_09160	COG2072	flavoprotein involved in K transport
FDF35_09175	COG1741	Belongs to the pirin family
FDF35_09180	COG1309	transcriptional regulator
FDF35_09190	COG0300	oxidoreductase activity
FDF35_09195	COG2072	flavoprotein involved in K transport
FDF35_09200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDF35_09245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF35_09260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF35_09275	COG2814	Major facilitator Superfamily
FDF35_09280	COG1024	Enoyl-CoA hydratase
FDF35_09285	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_09295	COG1960	acyl-CoA dehydrogenase activity
FDF35_09320	COG0697	spore germination
FDF35_09355	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FDF35_09370	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FDF35_09400	COG1766	The M ring may be actively involved in energy transduction
FDF35_09405	COG1677	Flagellar hook-basal body complex protein FliE
FDF35_09410	COG1558	bacterial-type flagellum-dependent cell motility
FDF35_09420	COG1706	bacterial-type flagellum-dependent cell motility
FDF35_09425	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FDF35_09435	COG4786	Flagellar basal body rod
FDF35_09445	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDF35_09450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDF35_09455	COG1684	flagellar biosynthetic protein fliR
FDF35_09460	COG1987	bacterial-type flagellum assembly
FDF35_09515	COG1113	amino acid transport
FDF35_09535	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_09555	COG0531	amino acid
FDF35_09650	COG0583	DNA-binding transcription factor activity
FDF35_09660	COG0251	oxidation-reduction process
FDF35_09690	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FDF35_09785	COG2161	toxin-antitoxin pair type II binding
FDF35_09800	COG0582	viral genome integration into host DNA
FDF35_09810	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF35_09810	COG1902	pentaerythritol trinitrate reductase activity
FDF35_09820	COG3706	GGDEF domain
FDF35_09820	COG5001	Diguanylate cyclase
FDF35_09820	COG4251	negative regulation of phosphorylation
FDF35_09820	COG2203	Gaf domain
FDF35_09830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF35_09850	COG4172	Belongs to the ABC transporter superfamily
FDF35_09855	COG4239	(ABC) transporter, permease
FDF35_09870	COG1388	LysM domain
FDF35_09870	COG0741	lytic transglycosylase activity
FDF35_09870	COG0741	lytic transglycosylase activity
FDF35_09870	COG1388	LysM domain
FDF35_09875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF35_09915	COG0583	DNA-binding transcription factor activity
FDF35_09920	COG1279	arginine transmembrane transporter activity
FDF35_09940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF35_09945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF35_09950	COG0006	proline dipeptidase activity
FDF35_10035	COG0739	heme binding
FDF35_10050	COG1598	PFAM Uncharacterised protein family UPF0150
FDF35_10160	COG5410	chromosome segregation
FDF35_10345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDF35_10365	COG3384	dioxygenase
FDF35_10375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF35_10380	COG2878	Part of a membrane complex involved in electron transport
FDF35_10385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDF35_10410	COG0768	penicillin binding
FDF35_10415	COG0742	ribosomal rna small subunit methyltransferase
FDF35_10430	COG0830	nickel cation binding
FDF35_10440	COG0804	urea catabolic process
FDF35_10480	COG1253	flavin adenine dinucleotide binding
FDF35_10490	COG2851	Citrate transporter
FDF35_10540	COG1773	rubredoxin
FDF35_10545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF35_10555	COG0583	DNA-binding transcription factor activity
FDF35_10585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDF35_10590	COG4181	ATPase activity
FDF35_10635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF35_10655	COG0306	phosphate transporter
FDF35_10680	COG3958	Transketolase
FDF35_10690	COG2271	Major facilitator Superfamily
FDF35_10695	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_10700	COG0583	DNA-binding transcription factor activity
FDF35_10720	COG2223	nitrite transmembrane transporter activity
FDF35_10725	COG2207	Transcriptional regulator
FDF35_10740	COG0477	Major facilitator Superfamily
FDF35_10750	COG0028	Belongs to the TPP enzyme family
FDF35_10765	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_10770	COG2267	carboxylic ester hydrolase activity
FDF35_10780	COG2271	Major facilitator Superfamily
FDF35_10795	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_10815	COG1414	Transcriptional regulator
FDF35_10830	COG1024	Enoyl-CoA hydratase
FDF35_10840	COG1215	transferase activity, transferring glycosyl groups
FDF35_10855	COG4681	YaeQ
FDF35_10865	COG0523	cobalamin synthesis protein
FDF35_10875	COG1607	acyl-coa hydrolase
FDF35_10885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF35_10890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF35_10895	COG1309	transcriptional regulator
FDF35_10920	COG2040	homocysteine
FDF35_10925	COG0531	amino acid
FDF35_10980	COG1595	DNA-templated transcription, initiation
FDF35_10990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF35_10995	COG0477	Major facilitator Superfamily
FDF35_11165	COG2026	Addiction module toxin, RelE StbE family
FDF35_11365	COG1484	DNA-dependent DNA replication
FDF35_11455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF35_11520	COG0405	Gamma-glutamyltransferase
FDF35_11525	COG2814	Major facilitator Superfamily
FDF35_11535	COG2050	protein possibly involved in aromatic compounds catabolism
FDF35_11550	COG1090	epimerase
FDF35_11570	COG0420	3'-5' exonuclease activity
FDF35_11600	COG0735	belongs to the Fur family
FDF35_11605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDF35_11630	COG0121	glutamine amidotransferase
FDF35_11645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF35_11655	COG0210	DNA helicase
FDF35_11660	COG2885	chlorophyll binding
FDF35_11665	COG0204	Acyl-transferase
FDF35_11680	COG2894	cell division
FDF35_11700	COG1280	lysine exporter protein (LysE YggA)
FDF35_11705	COG1674	ftsk spoiiie
FDF35_11710	COG0492	ferredoxin-NADP+ reductase activity
FDF35_11715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDF35_11725	COG0456	acetyltransferase
FDF35_11785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDF35_11785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF35_11805	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_11825	COG0473	3-isopropylmalate dehydrogenase activity
FDF35_11830	COG0583	DNA-binding transcription factor activity
FDF35_11850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF35_11875	COG0564	pseudouridine synthase activity
FDF35_11885	COG0358	DNA primase activity
FDF35_11900	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDF35_11930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDF35_11960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDF35_11970	COG0352	thiamine-phosphate diphosphorylase activity
FDF35_11970	COG0351	phosphomethylpyrimidine kinase
FDF35_11970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF35_11975	COG1652	LysM domain
FDF35_12000	COG1399	metal-binding, possibly nucleic acid-binding protein
FDF35_12005	COG3101	peptidyl-lysine hydroxylation
FDF35_12010	COG0009	L-threonylcarbamoyladenylate synthase
FDF35_12015	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDF35_12020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDF35_12035	COG4106	trans-aconitate 2-methyltransferase activity
FDF35_12050	COG0596	Alpha beta hydrolase
FDF35_12050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF35_12050	COG2226	methyltransferase
FDF35_12055	COG1877	trehalose-phosphatase activity
FDF35_12060	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDF35_12065	COG2223	nitrite transmembrane transporter activity
FDF35_12085	COG1196	nuclear chromosome segregation
FDF35_12095	COG0730	response to heat
FDF35_12110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDF35_12120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF35_12180	COG0489	protein tyrosine kinase activity
FDF35_12190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF35_12190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF35_12220	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDF35_12225	COG2081	HI0933 family
FDF35_12255	COG0583	DNA-binding transcription factor activity
FDF35_12275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDF35_12280	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF35_12310	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDF35_12345	COG2205	protein histidine kinase activity
FDF35_12350	COG0745	RESPONSE REGULATOR receiver
FDF35_12370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDF35_12395	COG0419	ATPase involved in DNA repair
FDF35_12420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_12425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDF35_12435	COG0583	DNA-binding transcription factor activity
FDF35_12455	COG1473	amidohydrolase
FDF35_12465	COG0583	DNA-binding transcription factor activity
FDF35_12485	COG0583	DNA-binding transcription factor activity
FDF35_12490	COG1053	succinate dehydrogenase
FDF35_12500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDF35_12505	COG2814	Major facilitator Superfamily
FDF35_12510	COG1960	acyl-CoA dehydrogenase activity
FDF35_12515	COG0583	DNA-binding transcription factor activity
FDF35_12520	COG1063	alcohol dehydrogenase
FDF35_12555	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDF35_12560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDF35_12565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF35_12585	COG2132	Multicopper oxidase
FDF35_12595	COG0561	phosphatase activity
FDF35_12600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDF35_12610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FDF35_12625	COG1214	PFAM Peptidase M22, glycoprotease
FDF35_12685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDF35_12690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDF35_12695	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDF35_12755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF35_12765	COG1846	Transcriptional regulator
FDF35_12770	COG1764	response to oxidative stress
FDF35_12815	COG0037	tRNA processing
FDF35_12825	COG0248	Ppx GppA phosphatase
FDF35_12855	COG0072	phenylalanine-tRNA ligase activity
FDF35_12880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FDF35_12895	COG1238	metal cluster binding
FDF35_12900	COG0625	glutathione transferase activity
FDF35_12920	COG0318	PFAM AMP-dependent synthetase and ligase
FDF35_12925	COG3028	Belongs to the UPF0307 family
FDF35_12930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF35_12950	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDF35_12955	COG0617	tRNA 3'-terminal CCA addition
FDF35_12960	COG1555	photosystem II stabilization
FDF35_12965	COG3956	TIGRFAM MazG family protein
FDF35_12975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF35_12995	COG2205	protein histidine kinase activity
FDF35_12995	COG0784	Response regulator, receiver
FDF35_12995	COG5002	protein histidine kinase activity
FDF35_13000	COG1024	Enoyl-CoA hydratase
FDF35_13005	COG2084	Dehydrogenase
FDF35_13010	COG3622	Belongs to the hyi family
FDF35_13025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FDF35_13030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDF35_13035	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDF35_13040	COG0697	spore germination
FDF35_13050	COG2814	Major facilitator Superfamily
FDF35_13055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF35_13065	COG0583	DNA-binding transcription factor activity
FDF35_13075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDF35_13085	COG0084	hydrolase, TatD family'
FDF35_13100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDF35_13135	COG0440	acetolactate synthase activity
FDF35_13140	COG0028	Belongs to the TPP enzyme family
FDF35_13165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_13175	COG1538	Outer membrane efflux protein
FDF35_13190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDF35_13195	COG1162	GTPase activity
FDF35_13205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDF35_13245	COG1426	Protein conserved in bacteria
FDF35_13280	COG0793	Belongs to the peptidase S41A family
FDF35_13295	COG2267	carboxylic ester hydrolase activity
FDF35_13305	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_13310	COG3265	gluconokinase activity
FDF35_13320	COG0800	Aldolase
FDF35_13330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDF35_13335	COG0280	phosphate acetyltransferase
FDF35_13335	COG0857	belongs to the CobB CobQ family
FDF35_13340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF35_13340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF35_13360	COG0740	serine-type endopeptidase activity
FDF35_13370	COG4774	siderophore transport
FDF35_13380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDF35_13390	COG2813	Specifically methylates the guanine in position
FDF35_13390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF35_13495	COG0788	formyltetrahydrofolate deformylase activity
FDF35_13510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDF35_13515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDF35_13520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDF35_13520	COG4651	solute:proton antiporter activity
FDF35_13540	COG0724	RNA recognition motif
FDF35_13545	COG0210	DNA helicase
FDF35_13570	COG1733	regulation of RNA biosynthetic process
FDF35_13590	COG1280	lysine exporter protein (LysE YggA)
FDF35_13595	COG1560	Kdo2-lipid A biosynthetic process
FDF35_13605	COG1301	dicarboxylic acid transport
FDF35_13660	COG0473	3-isopropylmalate dehydrogenase activity
FDF35_13725	COG0583	DNA-binding transcription factor activity
FDF35_13735	COG0625	glutathione transferase activity
FDF35_13740	COG2378	regulation of single-species biofilm formation
FDF35_13745	COG0546	phosphoglycolate phosphatase activity
FDF35_13760	COG1530	ribonuclease E activity
FDF35_13780	COG0583	DNA-binding transcription factor activity
FDF35_13785	COG4221	oxidoreductase activity
FDF35_13790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDF35_13800	COG0534	Mate efflux family protein
FDF35_13815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDF35_13855	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDF35_13875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF35_13885	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDF35_13885	COG0644	oxidoreductase
FDF35_13895	COG0425	Belongs to the sulfur carrier protein TusA family
FDF35_13900	COG4535	Mg2 and Co2 transporter CorC
FDF35_13910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF35_13930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDF35_13935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDF35_13935	COG0475	glutathione-regulated potassium exporter activity
FDF35_13950	COG0484	heat shock protein binding
FDF35_13955	COG0789	Transcriptional regulator
FDF35_13960	COG0598	Magnesium transport protein CorA
FDF35_13980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDF35_13985	COG1074	ATP-dependent DNA helicase activity
FDF35_13990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDF35_14010	COG2226	methyltransferase
FDF35_14030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDF35_14045	COG2111	Na H antiporter
FDF35_14045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF35_14050	COG1006	Multisubunit Na H antiporter MnhC subunit
FDF35_14055	COG0651	ATP synthesis coupled electron transport
FDF35_14065	COG2212	antiporter activity
FDF35_14085	COG0195	Participates in both transcription termination and antitermination
FDF35_14135	COG0237	dephospho-CoA kinase activity
FDF35_14145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF35_14160	COG0497	DNA recombination
FDF35_14170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDF35_14200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF35_14200	COG2169	Transcriptional regulator
FDF35_14205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDF35_14260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDF35_14275	COG0326	Molecular chaperone. Has ATPase activity
FDF35_14290	COG2056	Na+-H+ antiporter family
FDF35_14295	COG0596	Alpha beta hydrolase
FDF35_14390	COG0546	phosphoglycolate phosphatase activity
FDF35_14395	COG1716	ATPase activity
FDF35_14440	COG0181	hydroxymethylbilane synthase activity
FDF35_14450	COG3275	phosphorelay sensor kinase activity
FDF35_14470	COG1538	Outer membrane efflux protein
FDF35_14475	COG0697	spore germination
FDF35_14500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF35_14505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDF35_14515	COG0772	Belongs to the SEDS family
FDF35_14540	COG4974	Belongs to the 'phage' integrase family
FDF35_14545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF35_14555	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDF35_14565	COG2197	response regulator
FDF35_14580	COG0793	Belongs to the peptidase S41A family
FDF35_14585	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDF35_14590	COG0795	lipopolysaccharide-transporting ATPase activity
FDF35_14630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDF35_14630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDF35_14640	COG0004	ammonium transporteR
FDF35_14645	COG0347	Belongs to the P(II) protein family
FDF35_14655	COG0606	chelatase, subunit chli
FDF35_14680	COG1061	Type III restriction enzyme res subunit
FDF35_14695	COG0659	secondary active sulfate transmembrane transporter activity
FDF35_14700	COG0589	response to stress
FDF35_14740	COG0606	chelatase, subunit chli
FDF35_14745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF35_14750	COG0235	Class ii aldolase
FDF35_14755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF35_14775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDF35_14800	COG0477	Major facilitator Superfamily
FDF35_14805	COG2860	membrane
FDF35_14810	COG3012	SEC-C Motif Domain Protein
FDF35_14815	COG1253	flavin adenine dinucleotide binding
FDF35_14825	COG2814	Major facilitator Superfamily
FDF35_14835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF35_14870	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDF35_14915	COG1309	transcriptional regulator
FDF35_14950	COG0758	DNA mediated transformation
FDF35_14960	COG0697	spore germination
FDF35_14965	COG1309	transcriptional regulator
FDF35_14980	COG0386	Belongs to the glutathione peroxidase family
FDF35_15050	COG1121	(ABC) transporter
FDF35_15060	COG1280	lysine exporter protein (LysE YggA)
FDF35_15065	COG2837	iron assimilation
FDF35_15075	COG0281	malic enzyme
FDF35_15120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF35_15120	COG0519	Catalyzes the synthesis of GMP from XMP
FDF35_15125	COG4399	Belongs to the UPF0754 family
FDF35_15130	COG2259	Doxx family
FDF35_15135	COG0586	Pfam SNARE associated Golgi protein
FDF35_15150	COG1192	Involved in chromosome partitioning
FDF35_15160	COG0271	Belongs to the BolA IbaG family
FDF35_15180	COG2267	carboxylic ester hydrolase activity
FDF35_15200	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FDF35_15200	COG3321	synthase
FDF35_15200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDF35_15200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDF35_15205	COG1960	acyl-CoA dehydrogenase activity
FDF35_15215	COG2197	response regulator
FDF35_15225	COG3916	Acyl-homoserine-lactone synthase
FDF35_15235	COG1024	Enoyl-CoA hydratase
FDF35_15240	COG1024	Enoyl-CoA hydratase
FDF35_15245	COG1960	acyl-CoA dehydrogenase activity
FDF35_15250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF35_15270	COG1113	amino acid transport
FDF35_15275	COG1113	amino acid transport
FDF35_15280	COG0251	oxidation-reduction process
FDF35_15295	COG1522	sequence-specific DNA binding
FDF35_15320	COG0564	pseudouridine synthase activity
FDF35_15410	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDF35_15425	COG1802	Transcriptional regulator
FDF35_15435	COG1448	Aminotransferase
FDF35_15440	COG0277	FAD linked oxidase domain protein
FDF35_15450	COG2186	Transcriptional regulator
FDF35_15460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF35_15465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF35_15480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDF35_15485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDF35_15490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDF35_15540	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_15545	COG1083	cytidylyl-transferase
FDF35_15550	COG0673	inositol 2-dehydrogenase activity
FDF35_15555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDF35_15570	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDF35_15575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDF35_15585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDF35_15590	COG1596	polysaccharide export
FDF35_15620	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDF35_15675	COG0546	phosphoglycolate phosphatase activity
FDF35_15680	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_15700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF35_15705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF35_15710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF35_15715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF35_15720	COG1116	anion transmembrane transporter activity
FDF35_15725	COG1309	transcriptional regulator
FDF35_15730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDF35_15740	COG0196	riboflavin kinase activity
FDF35_15745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDF35_15755	COG1047	Peptidyl-prolyl cis-trans
FDF35_15795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDF35_15875	COG2951	lytic endotransglycosylase activity
FDF35_15880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDF35_15900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDF35_15910	COG0671	phosphoesterase, PA-phosphatase related
FDF35_15915	COG0861	Integral membrane protein TerC family
FDF35_15925	COG0754	glutathionylspermidine amidase activity
FDF35_15935	COG0402	S-adenosylhomocysteine deaminase activity
FDF35_15950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF35_15955	COG1230	cation diffusion facilitator family transporter
FDF35_15970	COG0706	membrane insertase activity
FDF35_15985	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FDF35_15995	COG0592	DNA-directed DNA polymerase activity
FDF35_16005	COG0187	DNA topoisomerase II activity
FDF35_16015	COG0586	Pfam SNARE associated Golgi protein
FDF35_16020	COG0488	(ABC) transporter
FDF35_16045	COG0596	Alpha beta hydrolase
FDF35_16050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDF35_16055	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDF35_16100	COG0733	neurotransmitter:sodium symporter activity
FDF35_16135	COG0583	DNA-binding transcription factor activity
FDF35_16140	COG2233	PERMEase
FDF35_16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_16190	COG2814	Major facilitator Superfamily
FDF35_16195	COG0656	L-ascorbic acid biosynthetic process
FDF35_16200	COG0583	DNA-binding transcription factor activity
FDF35_16215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF35_16220	COG1064	alcohol dehydrogenase
FDF35_16225	COG2818	Glycosylase
FDF35_16240	COG1194	a g-specific adenine glycosylase
FDF35_16260	COG2983	Belongs to the UPF0260 family
FDF35_16265	COG2133	pyrroloquinoline quinone binding
FDF35_16270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDF35_16275	COG2116	formate transmembrane transporter activity
FDF35_16295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF35_16300	COG1335	isochorismatase
FDF35_16305	COG0385	Bile acid
FDF35_16310	COG0534	Mate efflux family protein
FDF35_16315	COG1683	Conserved Protein
FDF35_16335	COG0625	glutathione transferase activity
FDF35_16345	COG1113	amino acid transport
FDF35_16355	COG0523	cobalamin synthesis protein
FDF35_16395	COG0010	Belongs to the arginase family
FDF35_16410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF35_16415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDF35_16425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDF35_16535	COG0436	Aminotransferase
FDF35_16540	COG2733	membrane
FDF35_16620	COG3150	esterase
FDF35_16630	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_16635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDF35_16645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF35_16655	COG2233	PERMEase
FDF35_16695	COG3706	GGDEF domain
FDF35_16710	COG1393	Belongs to the ArsC family
FDF35_16715	COG0708	Exodeoxyribonuclease III
FDF35_16740	COG0189	ligase activity
FDF35_16760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDF35_16770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDF35_16785	COG4942	peptidase
FDF35_16795	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF35_16805	COG2119	membrane
FDF35_16810	COG4774	siderophore transport
FDF35_16815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF35_16815	COG0426	domain, Protein
FDF35_16840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDF35_16870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDF35_16875	COG0668	transmembrane transport
FDF35_16885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF35_16890	COG1335	isochorismatase
FDF35_16895	COG1522	sequence-specific DNA binding
FDF35_16920	COG2205	protein histidine kinase activity
FDF35_16920	COG2198	Histidine kinase
FDF35_16920	COG0784	Response regulator, receiver
FDF35_16925	COG3162	membrane
FDF35_16930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF35_16940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF35_16965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDF35_16970	COG1309	transcriptional regulator
FDF35_16990	COG0352	thiamine-phosphate diphosphorylase activity
FDF35_16990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF35_16990	COG0351	phosphomethylpyrimidine kinase
FDF35_17000	COG2814	Major facilitator Superfamily
FDF35_17025	COG1113	amino acid transport
FDF35_17035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF35_17040	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_17050	COG1335	isochorismatase
FDF35_17085	COG0583	DNA-binding transcription factor activity
FDF35_17135	COG0667	Aldo Keto reductase
FDF35_17180	COG1733	regulation of RNA biosynthetic process
FDF35_17190	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF35_17200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDF35_17255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDF35_17270	COG2329	Antibiotic biosynthesis monooxygenase
FDF35_17305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDF35_17335	COG0427	acetyl-CoA hydrolase
FDF35_17350	COG0745	RESPONSE REGULATOR receiver
FDF35_17360	COG0659	secondary active sulfate transmembrane transporter activity
FDF35_17365	COG4221	oxidoreductase activity
FDF35_17375	COG0488	(ABC) transporter
FDF35_17440	COG0833	amino acid
FDF35_17485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDF35_17490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDF35_17505	COG2226	methyltransferase
FDF35_17555	COG0067	glutamate synthase
FDF35_17555	COG0069	glutamate synthase activity
FDF35_17555	COG0070	glutamate synthase
FDF35_17570	COG1704	LemA family
FDF35_17575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDF35_17595	COG3307	-O-antigen
FDF35_17615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF35_17630	COG0194	GDP metabolic process
FDF35_17680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDF35_17700	COG5380	lipid catabolic process
FDF35_17705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDF35_17730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDF35_17735	COG0277	FAD linked oxidase domain protein
FDF35_17745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDF35_17750	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF35_17765	COG1289	transmembrane transporter activity
FDF35_17770	COG2032	superoxide dismutase activity
FDF35_17775	COG0628	permease
FDF35_17780	COG1192	Involved in chromosome partitioning
FDF35_17810	COG0833	amino acid
FDF35_17815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF35_17820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF35_17830	COG1012	belongs to the aldehyde dehydrogenase family
FDF35_17870	COG0583	DNA-binding transcription factor activity
FDF35_17925	COG0517	IMP dehydrogenase activity
FDF35_17930	COG1983	PspC domain protein
FDF35_17940	COG1960	acyl-CoA dehydrogenase activity
FDF35_17955	COG0408	coproporphyrinogen oxidase activity
FDF35_17975	COG0513	Belongs to the DEAD box helicase family
FDF35_17985	COG1127	ABC transporter
FDF35_17990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDF35_18000	COG2854	intermembrane phospholipid transfer
FDF35_18010	COG0598	Magnesium transport protein CorA
FDF35_18020	COG0494	nUDIX hydrolase
FDF35_18025	COG1040	competence protein
FDF35_18050	COG1946	Acyl-CoA thioesterase
FDF35_18055	COG1301	dicarboxylic acid transport
FDF35_18070	COG1959	2 iron, 2 sulfur cluster binding
FDF35_18075	COG1017	nitric oxide dioxygenase activity
FDF35_18075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF35_18085	COG0433	COG0433 Predicted ATPase
FDF35_18090	COG0626	cystathionine gamma-synthase activity
FDF35_18210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDF35_18220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDF35_18245	COG1960	acyl-CoA dehydrogenase activity
FDF35_18250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDF35_18280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDF35_18285	COG0339	signal peptide processing
FDF35_18290	COG0557	exoribonuclease II activity
FDF35_18340	COG2169	Transcriptional regulator
FDF35_18350	COG1295	ribonuclease BN
FDF35_18385	COG1702	phosphate starvation-inducible protein PhoH
FDF35_18395	COG1196	nuclear chromosome segregation
FDF35_18395	COG0741	lytic transglycosylase activity
FDF35_18395	COG0739	heme binding
FDF35_18425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDF35_18430	COG1183	phosphatidylcholine synthase activity
FDF35_18475	COG1960	acyl-CoA dehydrogenase activity
FDF35_18480	COG1309	transcriptional regulator
FDF35_18495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDF35_18500	COG1960	acyl-CoA dehydrogenase activity
FDF35_18520	COG2969	positive regulation of protein catabolic process
FDF35_18530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDF35_18545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDF35_18550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDF35_18570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDF35_18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDF35_18595	COG2199	diguanylate cyclase activity
FDF35_18640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF35_18640	COG3453	Protein conserved in bacteria
FDF35_18655	COG1607	acyl-coa hydrolase
FDF35_18695	COG0613	PHP domain protein
FDF35_18700	COG3781	membrane
FDF35_18710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDF35_18715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDF35_18725	COG1862	Preprotein translocase
FDF35_18760	COG2205	protein histidine kinase activity
FDF35_18765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDF35_18785	COG0726	polysaccharide deacetylase
FDF35_18790	COG0463	Glycosyl transferase, family 2
FDF35_18795	COG0438	transferase activity, transferring glycosyl groups
FDF35_18810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDF35_18860	COG1960	acyl-CoA dehydrogenase activity
FDF35_18865	COG1960	acyl-CoA dehydrogenase activity
FDF35_18875	COG2205	protein histidine kinase activity
FDF35_18880	COG0745	RESPONSE REGULATOR receiver
FDF35_18885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDF35_18900	COG0584	glycerophosphoryl diester phosphodiesterase
FDF35_18905	COG2096	Adenosyltransferase
FDF35_18910	COG4206	TonB-dependent receptor
FDF35_18920	COG0133	tryptophan synthase activity
FDF35_18955	COG0285	dihydrofolate synthase activity
FDF35_18975	COG0450	alkyl hydroperoxide reductase
FDF35_18990	COG0477	Major facilitator Superfamily
FDF35_18995	COG1272	protein, Hemolysin III
FDF35_19025	COG0183	Belongs to the thiolase family
FDF35_19030	COG2207	Transcriptional regulator
FDF35_19050	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF35_19070	COG0183	Belongs to the thiolase family
FDF35_19080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDF35_19080	COG2885	chlorophyll binding
FDF35_19085	COG1690	Belongs to the RtcB family
FDF35_19090	COG0833	amino acid
FDF35_19130	COG2094	Belongs to the DNA glycosylase MPG family
FDF35_19135	COG4772	TonB-dependent receptor
FDF35_19140	COG1902	pentaerythritol trinitrate reductase activity
FDF35_19155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF35_19160	COG0354	folic acid binding
FDF35_19170	COG3189	MarR family transcriptional regulator
FDF35_19175	COG2824	Alkylphosphonate utilization operon protein PhnA
FDF35_19180	COG3422	double-strand break repair
FDF35_19220	COG0840	transmembrane signaling receptor activity
FDF35_19240	COG5510	response to toxic substance
FDF35_19250	COG2832	Protein of unknown function (DUF454)
FDF35_19255	COG1376	ErfK ybiS ycfS ynhG family protein
FDF35_19305	COG1289	transmembrane transporter activity
FDF35_19310	COG2814	Major facilitator Superfamily
FDF35_19330	COG1115	amino acid carrier protein
FDF35_19335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDF35_19340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDF35_19345	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDF35_19350	COG3590	peptidase
FDF35_19375	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF35_19385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF35_19390	COG1077	Cell shape determining protein MreB Mrl
FDF35_19395	COG1792	Involved in formation and maintenance of cell shape
FDF35_19400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDF35_19405	COG0424	maF-like protein
FDF35_19410	COG1530	ribonuclease E activity
FDF35_19420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF35_19430	COG0560	Phosphoserine phosphatase
FDF35_19440	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF35_19465	COG2207	Transcriptional regulator
FDF35_19515	COG1113	amino acid transport
FDF35_19525	COG2828	Protein conserved in bacteria
FDF35_19530	COG0142	geranyltranstransferase activity
FDF35_19535	COG2315	Protein conserved in bacteria
FDF35_19550	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDF35_19575	COG2194	sulfuric ester hydrolase activity
FDF35_19580	COG0745	RESPONSE REGULATOR receiver
FDF35_19585	COG0642	Histidine kinase
FDF35_19595	COG0004	ammonium transporteR
FDF35_19605	COG0583	DNA-binding transcription factor activity
FDF35_19620	COG2226	methyltransferase
FDF35_19625	COG0525	valine-tRNA ligase activity
FDF35_19635	COG1028	Short-chain dehydrogenase reductase Sdr
FDF35_19645	COG0393	Putative heavy-metal-binding
FDF35_19650	COG0393	Putative heavy-metal-binding
FDF35_19655	COG1538	Outer membrane efflux protein
FDF35_19665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF35_19670	COG0671	phosphoesterase, PA-phosphatase related
FDF35_19700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDF35_19715	COG1648	precorrin-2 dehydrogenase activity
FDF35_19715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDF35_19720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDF35_19735	COG0531	amino acid
FDF35_19750	COG0321	lipoyl(octanoyl) transferase activity
FDF35_19755	COG2921	Belongs to the UPF0250 family
FDF35_19790	COG2009	succinate dehydrogenase
FDF35_19795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDF35_19830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF35_19850	COG2354	Protein conserved in bacteria
FDF35_19855	COG2321	neutral zinc metallopeptidase
FDF35_19945	COG0589	response to stress
FDF35_20050	COG0739	heme binding
FDF35_20095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF35_20105	COG1192	Involved in chromosome partitioning
FDF35_20155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDF35_20305	COG3316	Transposase and inactivated derivatives
FDF35_20325	COG2207	Transcriptional regulator
FDF35_20330	COG0633	Ferredoxin
FDF35_20365	COG1309	transcriptional regulator
FDF35_20405	COG1373	ATPase (AAA superfamily
FDF35_20470	COG3316	Transposase and inactivated derivatives
FDF35_20475	COG0789	Transcriptional regulator
FDF35_20545	COG2233	PERMEase
FDF35_20560	COG4266	Belongs to the allantoicase family
FDF35_20565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF35_20570	COG0583	DNA-binding transcription factor activity
FDF35_20580	COG2233	PERMEase
FDF35_20585	COG3248	Nucleoside-binding outer membrane protein
FDF35_20600	COG0583	DNA-binding transcription factor activity
FDF35_20690	COG3316	Transposase and inactivated derivatives
FDF35_20705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDF35_20750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FDF35_20780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF35_20800	COG1192	Involved in chromosome partitioning
FDF35_20865	COG3316	Transposase and inactivated derivatives
FDF35_20955	COG0482	sulfurtransferase activity
FDF35_20975	COG3173	Aminoglycoside phosphotransferase
FDF35_20990	COG3316	Transposase and inactivated derivatives
FDF35_21045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF35_21095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDF35_21135	COG0501	Belongs to the peptidase M48B family
FDF35_21380	COG2832	Protein of unknown function (DUF454)