locus-tag class description FDF39_00010 ENOG4105JXH GntR family transcriptional regulator FDF39_00020 ENOG4105D6U Sodium Glutamate Symporter FDF39_00050 ENOG4105H4F exported protein FDF39_00085 ENOG4105C26 Dehydrogenase FDF39_00090 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FDF39_00120 ENOG4105D9P serine threonine protein kinase FDF39_00145 ENOG4105VCC 30S ribosomal protein S21 FDF39_00150 ENOG4105KTH gatB Yqey FDF39_00155 ENOG4105ERG peptidase m48, ste24p FDF39_00160 ENOG4105C5I Dehydrogenase FDF39_00175 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FDF39_00210 ENOG41069NU Nitroreductase FDF39_00220 ENOG4105C1J atp-dependent rna helicase FDF39_00225 ENOG4105VEQ Cold shock protein FDF39_00235 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDF39_00240 ENOG4105M08 Membrane FDF39_00270 ENOG4105CYB regulatoR FDF39_00275 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FDF39_00280 ENOG4105E0Y RtcB Protein FDF39_00300 ENOG4105CIN aminoacyl-histidine dipeptidase FDF39_00310 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FDF39_00315 ENOG4105CQC Prephenate dehydratase FDF39_00325 ENOG4105C1G acyl-Coa dehydrogenase FDF39_00330 ENOG4105CK2 sodium dicarboxylate symporter FDF39_00345 ENOG4105VUT cytoplasmic protein FDF39_00350 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FDF39_00355 ENOG4105BZ4 penicillin-binding protein FDF39_00365 ENOG4105M6F mutator MutT protein FDF39_00375 ENOG4105DHQ Histidine kinase FDF39_00380 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDF39_00390 ENOG4107QHF type ii secretion system protein e FDF39_00410 ENOG4108R96 Methyltransferase, YaeB family FDF39_00415 ENOG4105DP0 ferredoxin-NADP reductase FDF39_00420 ENOG4105JAB phenazine biosynthesis protein, phzf family FDF39_00425 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDF39_00430 ENOG4105CFP Peptidase U32 FDF39_00435 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FDF39_00450 ENOG4106YG3 ABC transporter FDF39_00455 ENOG4105DSP amino acid AbC transporter FDF39_00460 ENOG4105E89 ABC transporter FDF39_00470 ENOG4105ENT Efflux transporter rnd family, mfp subunit FDF39_00480 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDF39_00520 ENOG4105DA5 (ABC) transporter FDF39_00525 ENOG4105E3A (ABC) transporter FDF39_00540 ENOG4105CNI cell division protein FtsW FDF39_00545 ENOG4105CVE Lytic murein transglycosylase FDF39_00585 ENOG4105CE9 30S ribosomal protein S2 FDF39_00590 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FDF39_00600 ENOG4107RNU major facilitator superfamily MFS_1 FDF39_00610 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FDF39_00615 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FDF39_00635 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) FDF39_00640 ENOG4105SYT Methylenetetrahydrofolate reductase FDF39_00650 ENOG4105BZU Histidine kinase FDF39_00655 ENOG4105C6K Malic enzyme FDF39_00665 ENOG4105C0H protease FDF39_00670 ENOG4107QNR UPF0135 protein FDF39_00675 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDF39_00710 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) FDF39_00720 ENOG4105C5F glutamine synthetase FDF39_00735 ENOG4105DDQ anthranilate synthase FDF39_00740 ENOG4105CD8 aminopeptidase N FDF39_00770 ENOG4105C7W Xanthine dehydrogenase FDF39_00780 ENOG4105EUJ GTP cyclohydrolase i FDF39_00800 ENOG4105NX3 Membrane FDF39_00815 ENOG4105E4F Isochorismate synthase FDF39_00830 ENOG4108JJ7 ABC transporter FDF39_00835 ENOG4105BZ1 (ABC) transporter FDF39_00850 ENOG4105WQI isochorismatase FDF39_00855 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FDF39_00860 ENOG4105C0W non-ribosomal peptide synthetase FDF39_00880 ENOG4108IPW abc transporter atp-binding protein FDF39_00895 ENOG4105CEY Amp-dependent synthetase and ligase FDF39_00910 ENOG4105WWK YheO domain protein FDF39_00925 ENOG4105C2I pirin domain protein FDF39_00970 ENOG4105VCD cytoplasmic protein FDF39_00975 ENOG4105D22 carbon starvation protein FDF39_00985 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FDF39_00995 ENOG41066DG (EAL) domain protein FDF39_01005 ENOG4105DHU Bile acid FDF39_01020 ENOG4105DAN ATP-dependent protease FDF39_01025 ENOG4105EJC lysr family transcriptional regulator FDF39_01030 ENOG4108K5P (LipO)protein FDF39_01050 ENOG4105DZ1 carboxypeptidase FDF39_01055 ENOG4108Z0R Transferase FDF39_01075 ENOG4107QTF adenylosuccinate lyase FDF39_01095 ENOG4105ERU peptidase FDF39_01100 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FDF39_01110 ENOG4105C8U phosphate abc transporter FDF39_01115 ENOG4105CVA phosphate FDF39_01120 ENOG4105C85 amino acid FDF39_01125 ENOG4107RA9 decarboxylase FDF39_01130 ENOG4105F7P transcriptional regulator AsnC family FDF39_01140 ENOG4105DY8 decarboxylase FDF39_01145 ENOG4108JPW Aminotransferase FDF39_01170 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDF39_01185 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDF39_01190 ENOG4105D3G Pseudouridine synthase FDF39_01205 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FDF39_01235 ENOG4105JAB phenazine biosynthesis protein, phzf family FDF39_01240 ENOG4108ETY sodium dicarboxylate symporter FDF39_01245 ENOG4105EGI Transcriptional regulator FDF39_01275 ENOG4108R99 pseudouridine synthase FDF39_01280 ENOG4105E9K Isocitrate dehydrogenase FDF39_01290 ENOG4105DZ1 carboxypeptidase FDF39_01295 ENOG4105CEP NADH dehydrogenase FDF39_01300 ENOG4108YZY peptidylprolyl cis-trans isomerase FDF39_01305 ENOG4105CVP deoxyribo-dipyrimidine photolyase FDF39_01320 ENOG4107R8N Glycosyl transferase, family 2 FDF39_01360 ENOG4107QS8 (LipO)protein FDF39_01395 ENOG4105DTR rard protein FDF39_01405 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FDF39_01415 ENOG4105BZU Histidine kinase FDF39_01435 ENOG4105F7F Chaperone FDF39_01465 ENOG4105EMU Dehydrogenase FDF39_01470 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase FDF39_01475 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FDF39_01480 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) FDF39_01490 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FDF39_01505 ENOG4105C3F Signal peptidase i FDF39_01520 ENOG4105C0H protease FDF39_01525 ENOG4108IYU L-aspartate oxidase FDF39_01545 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FDF39_01550 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FDF39_01560 ENOG4108I5D sulfate abc transporter FDF39_01570 ENOG4108IJ6 ABC transporter FDF39_01575 ENOG4107R11 Transcriptional regulator FDF39_01590 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FDF39_01595 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FDF39_01610 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FDF39_01630 ENOG4108UKI Enoyl-CoA hydratase FDF39_01635 ENOG4105EGD dinuclear metal center protein, YbgI family FDF39_01640 ENOG4105C2C drug resistance transporter, Bcr CflA FDF39_01645 ENOG4108ETH Formylglycinamide ribotide synthetase FDF39_01665 ENOG4105CH2 amidohydrolase FDF39_01670 ENOG4107YD3 Thioesterase FDF39_01675 ENOG4105E02 MotA TolQ exbB proton channel FDF39_01680 ENOG4105M8F Biopolymer transport protein exbD tolR FDF39_01690 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) FDF39_01695 ENOG4105KCK Peptidoglycan-associated lipoprotein FDF39_01745 ENOG4105C02 permease FDF39_01755 ENOG4108V3E phosphoribosylglycinamide formyltransferase FDF39_01760 ENOG4107R6F Alpha Beta Hydrolase Fold protein FDF39_01765 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FDF39_01780 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FDF39_01815 ENOG4107KET secretion protein, HlyD family FDF39_01850 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDF39_01855 ENOG4105C10 Electron transfer flavoprotein FDF39_01860 ENOG4105BZJ Electron transfer flavoprotein FDF39_01865 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDF39_01870 ENOG4105N14 lysine exporter protein LysE YggA FDF39_01875 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FDF39_01895 ENOG4105C85 amino acid FDF39_01900 ENOG4105BZG amino acid carrier protein FDF39_01905 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FDF39_01915 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FDF39_01930 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FDF39_01935 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FDF39_01990 ENOG41088T4 Helicase IV FDF39_02005 ENOG4105E3B Multicopper oxidase FDF39_02020 ENOG4105GR3 Histidine kinase FDF39_02025 ENOG4105C59 p-type ATPase FDF39_02050 ENOG4108RRZ Transcription elongation factor GreB FDF39_02075 ENOG4105E4C Lytic transglycosylase catalytic FDF39_02090 ENOG4105BZS acriflavin resistance protein FDF39_02105 ENOG41080IJ Diacylglycerol kinase FDF39_02120 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FDF39_02135 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FDF39_02140 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FDF39_02145 ENOG4105CSH Transporter FDF39_02195 ENOG4105EEI dihydropteroate synthase FDF39_02205 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FDF39_02215 ENOG4105HBR Rna-binding protein FDF39_02230 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FDF39_02235 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FDF39_02245 ENOG4108IG5 Transcriptional regulator FDF39_02250 ENOG4108UQ8 endoribonuclease L-psp FDF39_02260 ENOG41080TK Universal stress protein FDF39_02275 ENOG4105PNM synthesis protein FDF39_02290 ENOG4105EEQ Na H antiporter FDF39_02295 ENOG4105CGZ zinc metallopeptidase FDF39_02300 ENOG4105CKW Inner membrane protein yedI FDF39_02310 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FDF39_02320 ENOG4107QN2 dihydrolipoyl dehydrogenase FDF39_02325 ENOG4105C7S Dehydrogenase FDF39_02330 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FDF39_02345 ENOG4105E33 succinate dehydrogenase FDF39_02355 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FDF39_02360 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FDF39_02390 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDF39_02395 ENOG41084BA UPF0250 protein FDF39_02400 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FDF39_02415 ENOG4105CUB amino acid FDF39_02430 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FDF39_02435 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FDF39_02450 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) FDF39_02480 ENOG410841Q phosphoesterase PA-phosphatase related protein FDF39_02485 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDF39_02490 ENOG4105BZS acriflavin resistance protein FDF39_02495 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDF39_02500 ENOG4105K8R UPF0145 protein FDF39_02505 ENOG4105K8R UPF0145 protein FDF39_02525 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FDF39_02530 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) FDF39_02555 ENOG4105DHQ Histidine kinase FDF39_02560 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDF39_02565 ENOG4105DIJ Phosphoethanolamine transferase FDF39_02600 ENOG4105D78 K07001 NTE family protein FDF39_02615 ENOG4105MSB protein, conserved in bacteria FDF39_02620 ENOG4105CTB Polyprenyl synthetase FDF39_02625 ENOG4105C7F AcnD-accessory protein PrpF FDF39_02630 ENOG4105C85 amino acid FDF39_02690 ENOG4105CF7 AraC family transcriptional regulator FDF39_02715 ENOG4108X0B nad(p)h dehydrogenase (quinone) FDF39_02725 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein FDF39_02735 ENOG4105D8T Acyltransferase FDF39_02745 ENOG4105C03 ribonuclease FDF39_02750 ENOG4108Z03 MAF-like protein FDF39_02755 ENOG4105VQ7 Rod shape-determining protein MreD FDF39_02760 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FDF39_02765 ENOG4105DFF Rod shape-determining protein mreb FDF39_02770 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FDF39_02780 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FDF39_02810 ENOG4105C9K Endothelin-converting enzyme 1 FDF39_02830 ENOG4105BZG amino acid carrier protein FDF39_02850 ENOG4105C2C drug resistance transporter, Bcr CflA FDF39_02855 ENOG4105EM2 membrane FDF39_02865 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FDF39_02905 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FDF39_02910 ENOG4105WD1 Membrane FDF39_02920 ENOG4106HKS Entericidin EcnA/B family FDF39_02950 ENOG4105C8Q Methyl-accepting chemotaxis FDF39_02955 ENOG4108ZGA chew protein FDF39_02960 ENOG4105M3Z response regulator FDF39_02965 ENOG4108UNF response regulator FDF39_02990 ENOG4105KWI UPF0339 protein FDF39_02995 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FDF39_03000 ENOG4105K78 MarR family Transcriptional regulator FDF39_03010 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FDF39_03015 ENOG4105T95 Thiol disulfide interChange protein FDF39_03025 ENOG4108N2Y auxin Efflux FDF39_03030 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_03035 ENOG4105CHB tonB-dependent Receptor FDF39_03040 ENOG4108VX5 3-methyladenine DNA glycosylase FDF39_03050 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FDF39_03070 ENOG4105C2W permease FDF39_03080 ENOG4108IQI permease FDF39_03085 ENOG4105E0Y RtcB Protein FDF39_03090 ENOG4108WHA ompa motb domain protein FDF39_03100 ENOG4105CHU acetyl-coa acetyltransferase FDF39_03120 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FDF39_03125 ENOG4105DZG Dehydrogenase FDF39_03130 ENOG4105TW1 Carbohydrate-selective porin OprB FDF39_03140 ENOG4108R6W Transcriptional regulator, ARAC family FDF39_03145 ENOG4105CHU acetyl-coa acetyltransferase FDF39_03165 ENOG41082BV acetyltransferase FDF39_03175 ENOG4108UT2 hemolysin iii FDF39_03180 ENOG4105CSH Transporter FDF39_03195 ENOG4105D3R alkyl hydroperoxide reductase FDF39_03215 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FDF39_03250 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FDF39_03260 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) FDF39_03265 ENOG4108WBT adenosyltransferase FDF39_03285 ENOG4105CNG UPF0061 protein FDF39_03290 ENOG4105E3W Two component transcriptional regulator (Winged helix family FDF39_03295 ENOG4105EB3 Histidine kinase FDF39_03305 ENOG4105CSU acyl-Coa dehydrogenase FDF39_03310 ENOG4105CSU acyl-Coa dehydrogenase FDF39_03340 ENOG4105UGU tonB-dependent Receptor FDF39_03400 ENOG4108PQP glycosyl transferase group 1 FDF39_03410 ENOG4107BJW polysaccharide deacetylase FDF39_03425 ENOG4105CM2 brancheD-chain amino acid aminotransferase FDF39_03430 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FDF39_03435 ENOG4105BZU Histidine kinase FDF39_03470 ENOG4105VIE preprotein translocase, subunit YajC FDF39_03475 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDF39_03480 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDF39_03485 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FDF39_03495 ENOG4105FFC UPF0187 protein FDF39_03500 ENOG4105DB7 PHP domain protein FDF39_03510 ENOG4105K9H YciI-like protein FDF39_03540 ENOG4105NAU thioesterase Superfamily protein FDF39_03550 ENOG4107U2T alpha beta FDF39_03555 ENOG4107QPB Beta-lactamase domain protein FDF39_03565 ENOG4107QN2 dihydrolipoyl dehydrogenase FDF39_03605 ENOG4108KHX Diguanylate cyclase FDF39_03610 ENOG4105UYK outer membrane protein a FDF39_03620 ENOG4107RZC phospholipase d FDF39_03630 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FDF39_03650 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FDF39_03655 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FDF39_03660 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FDF39_03670 ENOG4108UJD 30S ribosomal protein S9 FDF39_03675 ENOG4107MKT Stringent starvation protein a FDF39_03680 ENOG4105KB2 stringent starvation protein b FDF39_03700 ENOG4105C1G acyl-Coa dehydrogenase FDF39_03745 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FDF39_03750 ENOG4105D6S protein involved in catabolism of external DNA FDF39_03780 ENOG4105E4C Lytic transglycosylase catalytic FDF39_03790 ENOG4105C9A Phoh family FDF39_03820 ENOG4105CS1 NAD(P)H quinone oxidoreductase FDF39_03825 ENOG4107S2Z UPF0761 membrane protein FDF39_03835 ENOG4108K2B transcriptional regulator FDF39_03840 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FDF39_03885 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FDF39_03890 ENOG4105DGW oligopeptidase A FDF39_03895 ENOG4105VKU nucleicacid-binding protein FDF39_03930 ENOG4105C1G acyl-Coa dehydrogenase FDF39_03955 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FDF39_03965 ENOG41067V7 50S ribosomal protein L36 FDF39_03970 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FDF39_04080 ENOG41089BK Glutamine amido-transferase FDF39_04085 ENOG4105C28 cystathionine FDF39_04090 ENOG4105D7A ATP-binding protein FDF39_04100 ENOG4105KPV Transcriptional regulator FDF39_04120 ENOG4105C29 acyl-CoA thioesterase FDF39_04140 ENOG4105CB5 ATP-dependent DNA helicase recG FDF39_04145 ENOG4105MJ2 Competence protein FDF39_04155 ENOG4108URH decarboxylase FDF39_04160 ENOG4105D7N magnesium and cobalt transport protein CorA FDF39_04170 ENOG4105E3I toluene tolerance FDF39_04180 ENOG4105CY3 ABC transporter, permease FDF39_04185 ENOG4105DHJ ABC, transporter FDF39_04195 ENOG4105C1J atp-dependent rna helicase FDF39_04200 ENOG4105ECY inositol monophosphatase FDF39_04215 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) FDF39_04240 ENOG41067S9 phage shock protein C, PspC FDF39_04245 ENOG4105W87 Cbs domain FDF39_04320 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FDF39_04345 ENOG4105C26 Dehydrogenase FDF39_04355 ENOG4105C8Y Acetylornithine aminotransferase FDF39_04360 ENOG4105D82 Glutamate dehydrogenase FDF39_04365 ENOG4108IQI permease FDF39_04400 ENOG4105IPI Membrane FDF39_04405 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDF39_04410 ENOG4105EM2 membrane FDF39_04415 ENOG4107QF7 multi-drug FDF39_04425 ENOG4105NF4 modulator of drug activity FDF39_04430 ENOG4105VRH Antibiotic biosynthesis monooxygenase FDF39_04440 ENOG4105CQB FAD linked oxidase domain protein FDF39_04445 ENOG4108JQ1 Dehydrogenase FDF39_04470 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FDF39_04475 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) FDF39_04480 ENOG4107IFA Lipase (EC 3.1.1.3) FDF39_04495 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FDF39_04555 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FDF39_04565 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDF39_04570 ENOG4105KME endoribonuclease L-psp FDF39_04580 ENOG4108UQY Iron-storage protein FDF39_04585 ENOG4108YSG O-Antigen polymerase FDF39_04605 ENOG4105HA9 of methanol dehydrogenase type FDF39_04610 ENOG4108V0P LemA family FDF39_04620 ENOG4105BZ8 glutamate synthase FDF39_04625 ENOG4105CBC glutamate synthase FDF39_04645 ENOG4105E4G Type IV pilus FDF39_04670 ENOG4108JQC penicillin-binding protein 1A FDF39_04675 ENOG4105DHI Methyltransferase FDF39_04690 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FDF39_04695 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FDF39_04700 ENOG4105CJN penicillin-binding protein FDF39_04715 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FDF39_04740 ENOG4108IQI permease FDF39_04805 ENOG4105C5H ABC transporter FDF39_04815 ENOG4105PDP Short chain dehydrogenase FDF39_04820 ENOG4105CHH sulfate transporter FDF39_04830 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FDF39_04835 ENOG4105E0F Histidine kinase FDF39_04845 ENOG4105CYC Transferase FDF39_04875 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FDF39_04895 ENOG4105BZ1 (ABC) transporter FDF39_04910 ENOG41061CK Antibiotic biosynthesis monooxygenase FDF39_04925 ENOG4105CUV Homoserine Kinase FDF39_04980 ENOG4108UQN AraC family transcriptional regulator FDF39_04990 ENOG4105C2J ABC transporter FDF39_05015 ENOG4105CPC Aldo Keto reductase FDF39_05065 ENOG4106NZI LysR family Transcriptional regulator FDF39_05070 ENOG4105D94 Major Facilitator Superfamily FDF39_05095 ENOG4105EUB pirin domain protein FDF39_05100 ENOG4105CHJ isochorismatase hydrolase FDF39_05110 ENOG4105C26 Dehydrogenase FDF39_05115 ENOG4108JPW Aminotransferase FDF39_05125 ENOG4105C85 amino acid FDF39_05135 ENOG4108UMN azlc family FDF39_05145 ENOG4108UUM single-stranded DNA-binding protein FDF39_05150 ENOG4107RDB Major Facilitator FDF39_05160 ENOG4105DWF phosphomethylpyrimidine kinase FDF39_05165 ENOG4105RA2 Membrane FDF39_05175 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FDF39_05180 ENOG4108WUH Transcriptional regulator, TetR family FDF39_05185 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FDF39_05190 ENOG4105BZU Histidine kinase FDF39_05200 ENOG4105C94 Transporter FDF39_05210 ENOG4107QN1 sodium solute FDF39_05215 ENOG41062QD Membrane FDF39_05220 ENOG4105BZU Histidine kinase FDF39_05235 ENOG4108UZX fmn reductase FDF39_05240 ENOG4105FBW Monooxygenase FDF39_05250 ENOG4108W2Y isochorismatase FDF39_05255 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FDF39_05265 ENOG4105D64 Mechanosensitive ion channel FDF39_05280 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_05300 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FDF39_05315 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FDF39_05330 ENOG4105E0K tonB-dependent siderophore receptor FDF39_05345 ENOG4107QSN dihydrolipoamide acetyltransferase FDF39_05355 ENOG41063SB peptidase FDF39_05370 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FDF39_05375 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FDF39_05380 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FDF39_05400 ENOG4105D7Z glutathione synthase FDF39_05420 ENOG4105CGK Exodeoxyribonuclease III FDF39_05425 ENOG4105KUZ arsenate reductase FDF39_05440 ENOG4105BZU Histidine kinase FDF39_05445 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FDF39_05475 ENOG41084YZ Hydrolase FDF39_05490 ENOG41061H0 Monooxygenase FDF39_05500 ENOG4108Z2U ureidoglycolate hydrolase FDF39_05510 ENOG4105IPS esterase FDF39_05540 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FDF39_05545 ENOG4105CS6 Rhs element vgr protein FDF39_05555 ENOG4105D9M gamma-glutamylcysteine synthetase FDF39_05570 ENOG4106BRA Membrane FDF39_05575 ENOG4105CHM Aminotransferase FDF39_05580 ENOG4107QJQ Mate efflux family protein FDF39_05595 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDF39_05600 ENOG4105BZU Histidine kinase FDF39_05615 ENOG4105KHC sulfurtransferase FDF39_05655 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FDF39_05670 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FDF39_05675 ENOG4108ZAI phosphatidylglycerophosphatase a FDF39_05685 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FDF39_05705 ENOG4105NI8 Cytosine-specific methyltransferase FDF39_05720 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FDF39_05735 ENOG41088SP formiminoglutamate hydrolase FDF39_05760 ENOG41090B9 response to stress FDF39_05765 ENOG4105CZE histidine utilization repressor FDF39_05775 ENOG4105CKI cobalamin synthesis protein FDF39_05785 ENOG4105C85 amino acid FDF39_05795 ENOG4108RXX maleylacetoacetate isomerase FDF39_05820 ENOG4107QI1 Mate efflux family protein FDF39_05825 ENOG4105C09 Bile acid FDF39_05830 ENOG4108RWI nicotinamidase FDF39_05835 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDF39_05855 ENOG4105S64 Formate nitrite transporter FDF39_05860 ENOG4105D1H recombination factor protein RarA FDF39_05865 ENOG4105D8V Glucose sorbosone dehydrogenase FDF39_05870 ENOG4108ZZ3 UPF0260 protein FDF39_05890 ENOG4105CEN a g-specific adenine glycosylase FDF39_05905 ENOG4108R3E Dna-3-methyladenine glycosylase i FDF39_05910 ENOG4105DQ4 alcohol dehydrogenase FDF39_05935 ENOG4105CV8 reductase FDF39_05940 ENOG4105F27 Major Facilitator FDF39_05980 ENOG4108IG5 Transcriptional regulator FDF39_05990 ENOG4105C2W permease FDF39_05995 ENOG4108W5M transcriptional regulator FDF39_06020 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FDF39_06030 ENOG4105C8J )-transporter FDF39_06075 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FDF39_06080 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) FDF39_06085 ENOG4105D74 hydrolase FDF39_06100 ENOG4108821 RND type efflux pump FDF39_06105 ENOG4108821 RND type efflux pump FDF39_06110 ENOG4108821 RND type efflux pump FDF39_06115 ENOG4105C5H ABC transporter FDF39_06120 ENOG4105DQR SNARE associated Golgi FDF39_06130 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDF39_06140 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FDF39_06150 ENOG4105VG0 50S ribosomal protein l34 FDF39_06165 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FDF39_06180 ENOG4105PGM cation diffusion facilitator family transporter FDF39_06185 ENOG4105T95 Thiol disulfide interChange protein FDF39_06195 ENOG4108UGV hypoxanthine phosphoribosyltransferase FDF39_06200 ENOG4107QUY Guanine deaminase FDF39_06210 ENOG4106032 Glutathionylspermidine synthase FDF39_06220 ENOG4105DU1 integral membrane protein, terc FDF39_06225 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FDF39_06235 ENOG4105DFU Cell wall formation (By similarity) FDF39_06250 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FDF39_06255 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FDF39_06260 ENOG4105CVE Lytic murein transglycosylase FDF39_06315 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FDF39_06355 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FDF39_06365 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FDF39_06370 ENOG4105DTN riboflavin biosynthesis protein ribF FDF39_06380 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FDF39_06385 ENOG4108R86 Transcriptional regulator FDF39_06390 ENOG4108VM9 ABC, transporter FDF39_06395 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDF39_06400 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FDF39_06405 ENOG4105GVF (ABC) transporter FDF39_06410 ENOG4105GVF (ABC) transporter FDF39_06415 ENOG4107QZM n-acetylglutamate synthase FDF39_06430 ENOG4105UBK short-chain dehydrogenase reductase FDF39_06435 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FDF39_06450 ENOG41062JF Transcriptional regulator FDF39_06475 ENOG4105HSS phospholipase C FDF39_06485 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FDF39_06490 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FDF39_06495 ENOG4105CJR Integral membrane protein (MviN FDF39_06500 ENOG4108V1T peptidylprolyl cis-trans isomerase FDF39_06505 ENOG4108V1T peptidylprolyl cis-trans isomerase FDF39_06520 ENOG4105DAY polysaccharide export protein FDF39_06525 ENOG4107QQG Dehydrogenase FDF39_06535 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FDF39_06540 ENOG4107SE4 UDP-N-acetylglucosamine 2-epimerase FDF39_06545 ENOG4105D2T synthase FDF39_06560 ENOG4105F0R Cytidylyltransferase FDF39_06610 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FDF39_06625 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FDF39_06640 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FDF39_06645 ENOG4105C6Y Udp-glucose 6-dehydrogenase FDF39_06655 ENOG4105CMR udp-glucose 4-epimerase FDF39_06660 ENOG4107QKV phosphomannomutase FDF39_06665 ENOG4105DAA L-lactate FDF39_06670 ENOG41073TP transcriptional regulator FDF39_06680 ENOG4105CXG d-lactate dehydrogenase FDF39_06690 ENOG4105DRR Transcriptional regulator, GntR family FDF39_06695 ENOG4105CR4 methylisocitrate lyase FDF39_06700 ENOG4105BZN citrate synthase FDF39_06705 ENOG4108I0Z Aconitate hydratase FDF39_06755 ENOG4105D3G Pseudouridine synthase FDF39_06780 ENOG4105EW9 transcriptional regulator AsnC family FDF39_06795 ENOG4105M4H endoribonuclease L-psp FDF39_06800 ENOG4105C85 amino acid FDF39_06805 ENOG4105C85 amino acid FDF39_06815 ENOG4105C26 Dehydrogenase FDF39_06820 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDF39_06830 ENOG4105C1G acyl-Coa dehydrogenase FDF39_06835 ENOG4105E39 Enoyl-CoA hydratase FDF39_06840 ENOG4105E39 Enoyl-CoA hydratase FDF39_06845 ENOG4105CSH Transporter FDF39_06895 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FDF39_06915 ENOG4107PSF BolA-like protein FDF39_06925 ENOG4107QJE Chromosome Partitioning Protein FDF39_06940 ENOG4105DQR SNARE associated Golgi FDF39_06945 ENOG4108VBZ doxx family FDF39_06950 ENOG4106MP8 UPF0754 membrane protein FDF39_06955 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FDF39_06975 ENOG4105EUB pirin domain protein FDF39_07000 ENOG4107R1I NAD-dependent malic enzyme FDF39_07010 ENOG4105EZR dyp-type peroxidase family protein FDF39_07020 ENOG4105FAV ABC, transporter FDF39_07025 ENOG4105FDK ABC transporter FDF39_07050 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FDF39_07085 ENOG41090VV Protein of unknown function (DUF2846) FDF39_07095 ENOG4108V06 Glutathione peroxidase FDF39_07105 ENOG4107RTG Major Facilitator superfamily FDF39_07110 ENOG4108IND Tetr family transcriptional regulator FDF39_07125 ENOG4105C79 DNA protecting protein DprA FDF39_07160 ENOG4105Y7M Transcriptional regulator, TetR family FDF39_07195 ENOG4105C6T cysteine synthase FDF39_07205 ENOG4105CS1 NAD(P)H quinone oxidoreductase FDF39_07225 ENOG4105CCT upf0313 protein FDF39_07240 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FDF39_07250 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDF39_07255 ENOG4108URH decarboxylase FDF39_07260 ENOG4105EE5 Membrane protein terC FDF39_07265 ENOG4105K5B UPF0225 protein FDF39_07270 ENOG4105EN6 Membrane FDF39_07275 ENOG41079KZ Major Facilitator Superfamily FDF39_07280 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDF39_07285 ENOG4105CEY Amp-dependent synthetase and ligase FDF39_07300 ENOG4105F0N pyrophosphate phospho-hydrolase FDF39_07305 ENOG41090KI Outer membrane porin FDF39_07315 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDF39_07320 ENOG4105FB2 class II Aldolase FDF39_07325 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDF39_07330 ENOG4105C0P Mg chelatase subunit ChlI FDF39_07380 ENOG4105CHH sulfate transporter FDF39_07395 ENOG4105F6A helicase FDF39_07405 ENOG4108HWY Beta-lactamase FDF39_07420 ENOG4105C0P Mg chelatase subunit ChlI FDF39_07435 ENOG4105BZU Histidine kinase FDF39_07485 ENOG4108K5H permease YjgP YjgQ family protein FDF39_07490 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FDF39_07495 ENOG4105CN1 protease FDF39_07500 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDF39_07505 ENOG4107TUY Histidine kinase FDF39_07515 ENOG41061WM D-Alanyl-D-Alanine FDF39_07525 ENOG4105D6E homoserine dehydrogenase FDF39_07530 ENOG4105T95 Thiol disulfide interChange protein FDF39_07535 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDF39_07545 ENOG4105CE1 Ferrous iron transport protein b FDF39_07560 ENOG4105CNI cell division protein FtsW FDF39_07565 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FDF39_07570 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FDF39_07575 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FDF39_07600 ENOG4108RNG Permease of the drug metabolite transporter FDF39_07605 ENOG4105DFG type I secretion outer membrane protein FDF39_07610 ENOG4108UTW Plays a role in the regulation of phosphate uptake FDF39_07625 ENOG4108HRK Histidine kinase FDF39_07630 ENOG4108NEV two component transcriptional regulator, LytTR family FDF39_07635 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FDF39_07660 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FDF39_07675 ENOG4105GVR general secretion pathway protein D FDF39_07680 ENOG4105TV9 FHA Domain-Containing protein FDF39_07685 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FDF39_07725 ENOG4105PM1 preprotein translocase subunit SecE FDF39_07730 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FDF39_07780 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FDF39_07785 ENOG4105D3Y Na H antiporter FDF39_07800 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FDF39_07815 ENOG4107ZXU DSBA oxidoreductase FDF39_07880 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FDF39_07885 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDF39_07915 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FDF39_07925 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FDF39_07940 ENOG4105C2N RNA methyltransferase TrmH family group 3 FDF39_07965 ENOG4107QHF type ii secretion system protein e FDF39_07975 ENOG4107EJC Preprotein translocase subunit SecG FDF39_08000 ENOG4105CHV Transcription elongation factor NusA FDF39_08015 ENOG4105KJM monovalent cation h antiporter subunit g FDF39_08020 ENOG4105W4C monovalent cation H antiporter subunit F FDF39_08025 ENOG4105SC1 monovalent cation H antiporter subunit E FDF39_08030 ENOG4107R4Z monovalent cation h antiporter subunit d FDF39_08035 ENOG4108ZE9 Monovalent cation H antiporter subunit C FDF39_08040 ENOG4105D65 subunit l FDF39_08055 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FDF39_08060 ENOG41061H0 Monooxygenase FDF39_08075 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FDF39_08085 ENOG4105CSR polyphosphate kinase 2 FDF39_08095 ENOG4105DSY exodeoxyribonuclease V, gamma FDF39_08100 ENOG4107QKA exodeoxyribonuclease V beta FDF39_08125 ENOG4107QUT magnesium and cobalt transport protein CorA FDF39_08130 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) FDF39_08135 ENOG4105DVC DnaJ domain protein FDF39_08150 ENOG4105CKD glutathione-regulated potassium-efflux system protein FDF39_08160 ENOG4105D7Q type ii secretion system FDF39_08165 ENOG4108VAU general secretion pathway protein G FDF39_08175 ENOG4108Z7R Chaperone CsaA FDF39_08180 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FDF39_08185 ENOG4108JU5 Magnesium and cobalt efflux protein FDF39_08190 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) FDF39_08200 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FDF39_08210 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FDF39_08225 ENOG4105C5X domain protein FDF39_08230 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) FDF39_08240 ENOG4105BZ8 glutamate synthase FDF39_08275 ENOG4107T8P acyl-Coa dehydrogenase FDF39_08285 ENOG4107QI1 Mate efflux family protein FDF39_08295 ENOG4105CSA Coproporphyrinogen iii oxidase FDF39_08315 ENOG4105CBN LysR family transcriptional regulator FDF39_08335 ENOG4105C03 ribonuclease FDF39_08345 ENOG4105EI2 Pseudouridine synthase FDF39_08350 ENOG4107XGZ Hydrolase FDF39_08355 ENOG4105D29 Helix-turn-helix type 11 domain protein FDF39_08370 ENOG4108W5M transcriptional regulator FDF39_08385 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FDF39_08410 ENOG4105DUM transcriptional regulator, lysR family FDF39_08435 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDF39_08495 ENOG4105CK2 sodium dicarboxylate symporter FDF39_08505 ENOG4105D1S lipid A biosynthesis FDF39_08510 ENOG4105N14 lysine exporter protein LysE YggA FDF39_08520 ENOG4105C5H ABC transporter FDF39_08525 ENOG41069P5 Protein slyX homolog FDF39_08535 ENOG4105KVH Transcriptional regulator FDF39_08545 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FDF39_08560 ENOG4105C4R Atp-dependent dna helicase FDF39_08565 ENOG4105VFU Rna-binding protein FDF39_08590 ENOG4105W0E 50S ribosomal protein L33 FDF39_08595 ENOG4105KDC 50s ribosomal protein l28 FDF39_08600 ENOG4107RGH Aldehyde dehydrogenase FDF39_08610 ENOG4105CIY formyltetrahydrofolate deformylase FDF39_08715 ENOG4105DWV Homoserine O-trans-acetylase FDF39_08725 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FDF39_08755 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FDF39_08775 ENOG4107GFK fumarate FDF39_08780 ENOG4108DNC Involved in acetate metabolism (By similarity) FDF39_08785 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FDF39_08790 ENOG4105C01 Dihydroxy-acid dehydratase FDF39_08795 ENOG4108UHU Aldolase FDF39_08800 ENOG4105C6Z Gluconate FDF39_08805 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FDF39_08810 ENOG4105C26 Dehydrogenase FDF39_08820 ENOG4106HB6 Alpha beta hydrolase FDF39_08835 ENOG4105CN1 protease FDF39_08850 ENOG4105WVQ Fe-S assembly protein IscX FDF39_08870 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) FDF39_08890 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FDF39_08910 ENOG4105VW4 glutaredoxin 3 FDF39_08925 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FDF39_08935 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FDF39_08940 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDF39_08945 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FDF39_08950 ENOG4105DJY efflux transporter, rnd family, mfp subunit FDF39_08975 ENOG4105C7K acetolactate synthase FDF39_08980 ENOG4108ZP8 Acetolactate synthase small subunit FDF39_08990 ENOG4105BZU Histidine kinase FDF39_09040 ENOG4105EMU Dehydrogenase FDF39_09045 ENOG410810E transcriptional regulator, lysR family FDF39_09050 ENOG4107QPD alcohol dehydrogenase FDF39_09055 ENOG4108JA1 polyketide synthase FDF39_09070 ENOG4105C4W S-formylglutathione hydrolase FDF39_09085 ENOG4108I6A alcohol dehydrogenase FDF39_09095 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_09105 ENOG4108WUH Transcriptional regulator, TetR family FDF39_09110 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein FDF39_09120 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium FDF39_09135 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FDF39_09150 ENOG4105F8V Hydrolase, tatD family FDF39_09160 ENOG4105CUZ uba thif-type nad fad binding protein FDF39_09170 ENOG4107RSM transcriptional regulator FDF39_09180 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDF39_09195 ENOG4106UX7 integral membrane protein FDF39_09200 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDF39_09205 ENOG4105W8H transhydrogenase (subunit alpha FDF39_09210 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDF39_09225 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FDF39_09230 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDF39_09235 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase FDF39_09240 ENOG4105BZU Histidine kinase FDF39_09245 ENOG4105C6T cysteine synthase FDF39_09260 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDF39_09270 ENOG4105DXN mazG family FDF39_09275 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FDF39_09280 ENOG4105DJ0 Poly(A) Polymerase FDF39_09285 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FDF39_09305 ENOG41080Z8 PHOSPHOCARRIER protein FDF39_09310 ENOG4105N42 UPF0307 protein FDF39_09315 ENOG4105CEY Amp-dependent synthetase and ligase FDF39_09335 ENOG4105CYM Glutathione S-transferase FDF39_09340 ENOG4105W39 Membrane FDF39_09355 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FDF39_09400 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FDF39_09420 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FDF39_09425 ENOG4105II7 pyrroline-5-carboxylate reductase FDF39_09430 ENOG4108VIA integral membrane protein FDF39_09435 ENOG4105C2M dna polymerase I FDF39_09455 ENOG4107QHF type ii secretion system protein e FDF39_09460 ENOG4108ZHJ Organic hydroperoxide resistance protein FDF39_09535 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FDF39_09540 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FDF39_09545 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FDF39_09555 ENOG4105CRQ synthase (Component I) FDF39_09585 ENOG4108Z0R Transferase FDF39_09590 ENOG41072GX Peptidase M22 Glycoprotease FDF39_09605 ENOG4105C4W S-formylglutathione hydrolase FDF39_09615 ENOG4105DJV ribulose-phosphate 3-epimerase FDF39_09620 ENOG4108HCJ Hydrolase FDF39_09630 ENOG4105E3B Multicopper oxidase FDF39_09635 ENOG4105VR0 copper resistance FDF39_09685 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDF39_09690 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FDF39_09695 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FDF39_09725 ENOG4105ETT transcriptional Regulator, LysR family FDF39_09730 ENOG4105C1G acyl-Coa dehydrogenase FDF39_09735 ENOG4107RGD Major Facilitator superfamily FDF39_09740 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FDF39_09750 ENOG4107EFR Flavocytochrome c FDF39_09755 ENOG4106P55 Transcriptional regulator FDF39_09775 ENOG4106P55 Transcriptional regulator FDF39_09805 ENOG4105ETT transcriptional Regulator, LysR family FDF39_09815 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FDF39_09820 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) FDF39_09840 ENOG4105JAB phenazine biosynthesis protein, phzf family FDF39_09850 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDF39_09860 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDF39_09870 ENOG4107EXC regulatoR FDF39_09875 ENOG4105E0F Histidine kinase FDF39_09885 ENOG4105BZU Histidine kinase FDF39_09905 ENOG4105GKE subunit e FDF39_09910 ENOG4107QIZ NADH dehydrogenase FDF39_09930 ENOG4107UFS subunit j FDF39_09940 ENOG4105D65 subunit l FDF39_09945 ENOG4105C8S subunit m FDF39_09965 ENOG4105DUM transcriptional regulator, lysR family FDF39_09970 ENOG4105DP0 ferredoxin-NADP reductase FDF39_09995 ENOG4105CBX hi0933 family FDF39_10030 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FDF39_10040 ENOG4105D1F ATP-binding protein FDF39_10100 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FDF39_10110 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FDF39_10125 ENOG4105HF0 Membrane FDF39_10135 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FDF39_10155 ENOG4106UW1 Major Facilitator superfamily FDF39_10160 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase FDF39_10165 ENOG4108K4C ec 3.1.3.12 FDF39_10170 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FDF39_10180 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FDF39_10185 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FDF39_10195 ENOG4105FE9 pseudouridine synthase FDF39_10200 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FDF39_10205 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FDF39_10210 ENOG4107RTD sua5 ycio yrdc ywlc family protein FDF39_10215 ENOG4108BPE -transporting atpase FDF39_10220 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FDF39_10230 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FDF39_10235 ENOG4105CHR reductase FDF39_10245 ENOG4109066 lysm domain bon superfamily protein FDF39_10250 ENOG4105DWF phosphomethylpyrimidine kinase FDF39_10260 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FDF39_10300 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FDF39_10330 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) FDF39_10345 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FDF39_10350 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FDF39_10355 ENOG4105C34 Pseudouridine synthase FDF39_10360 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FDF39_10420 ENOG41076J9 exonuclease VIII FDF39_10480 ENOG4105CDU Replicative dna helicase FDF39_10740 ENOG4105DFP Integrase FDF39_10750 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FDF39_10770 ENOG4105EJC lysr family transcriptional regulator FDF39_10775 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDF39_10780 ENOG4105C94 Transporter FDF39_10790 ENOG4105DVW rieske (2Fe-2S) FDF39_10795 ENOG4105C26 Dehydrogenase FDF39_10800 ENOG4105E3J oxidoreductase FDF39_10815 ENOG4105C4K Nad synthetase FDF39_10825 ENOG4105EUB pirin domain protein FDF39_10830 ENOG4108YXA Membrane FDF39_10875 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FDF39_10885 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) FDF39_10890 ENOG4105C3M thioredoxin reductase FDF39_10895 ENOG4105CNU cell division protein FtsK FDF39_10915 ENOG4107QMS site-determining protein FDF39_10930 ENOG4106HNH Acyl-transferase FDF39_10935 ENOG4108ZG0 Ompa motb domain protein FDF39_10940 ENOG4105C4R Atp-dependent dna helicase FDF39_10950 ENOG4107QKV phosphomannomutase FDF39_10965 ENOG4105E7A Glutamine amidotransferase FDF39_10995 ENOG41090R7 Ferric uptake FDF39_11000 ENOG4105CZX twitching motility protein FDF39_11005 ENOG4105CZX twitching motility protein FDF39_11010 ENOG4105DFA alanine racemase domain protein FDF39_11015 ENOG4105EYH Exonuclease FDF39_11040 ENOG4105ECP epimerase FDF39_11045 ENOG4105MWK D-amino acid dehydrogenase, small subunit FDF39_11050 ENOG4105D52 delta-aminolevulinic acid dehydratase FDF39_11055 ENOG4108VUY thioesterase Superfamily protein FDF39_11060 ENOG4105CW7 secretion protein, HlyD family FDF39_11065 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDF39_11070 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FDF39_11135 ENOG41083X2 DNA polymerase III, epsilon subunit FDF39_11420 ENOG4105K4U addiction module toxin, RelE StbE family FDF39_11460 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FDF39_11555 ENOG4105DFP Integrase FDF39_11600 ENOG4108UUM single-stranded DNA-binding protein FDF39_11690 ENOG4105NVB glycoside hydrolase, family 19 FDF39_11720 ENOG4105KT5 UmuD protein FDF39_11760 ENOG4105C54 Major Facilitator superfamily FDF39_11765 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDF39_11775 ENOG4108SF5 RNA Polymerase FDF39_11805 ENOG4108YNN Heme oxygenase FDF39_11835 ENOG4107QK5 Homocysteine s-methyltransferase FDF39_11860 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FDF39_11865 ENOG4105C94 Transporter FDF39_11870 ENOG4105C94 Transporter FDF39_11890 ENOG4105CKI cobalamin synthesis protein FDF39_11900 ENOG4108VWS Yaeq family FDF39_11915 ENOG4105CND Glycosyl transferase, family 2 FDF39_11925 ENOG4106YT9 Enoyl-CoA hydratase FDF39_11940 ENOG41069M3 Transcriptional regulator FDF39_11960 ENOG4105CHR reductase FDF39_11975 ENOG4105DJB Major Facilitator Superfamily FDF39_11985 ENOG4108MXF Alpha Beta Hydrolase FDF39_11990 ENOG4105CHR reductase FDF39_12005 ENOG4105C7K acetolactate synthase FDF39_12015 ENOG4105CSH Transporter FDF39_12020 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FDF39_12025 ENOG4105CSV Glutaminase FDF39_12030 ENOG4108R6W Transcriptional regulator, ARAC family FDF39_12035 ENOG4105EU0 Major facilitator Superfamily FDF39_12040 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FDF39_12065 ENOG4105C3R Methionine synthase FDF39_12070 ENOG4105CJ3 phosphate transporter FDF39_12090 ENOG4105E6M Sulphatase-modifying factor protein FDF39_12095 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FDF39_12110 ENOG4107RNH Outer membrane receptor FepA FDF39_12130 ENOG4108UJV acyl-CoA thioesterase i FDF39_12135 ENOG4108I0Y (ABC) transporter FDF39_12140 ENOG4105CV6 ABC transporter, permease FDF39_12145 ENOG4107U91 Rhomboid family FDF39_12170 ENOG4105C5Q Transcriptional regulator FDF39_12180 ENOG4107QZF nitrite reductase NADPH large subunit FDF39_12185 ENOG4105VCQ rubredoxin FDF39_12205 ENOG4108MRJ FDF39_12220 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FDF39_12235 ENOG4105D4T Citrate transporter FDF39_12245 ENOG4105C37 (CBS) domain FDF39_12255 ENOG4107RET Isocitrate lyase FDF39_12285 ENOG4105CQM Urea amidohydrolase subunit alpha FDF39_12295 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FDF39_12310 ENOG4106H78 methyltransferase FDF39_12315 ENOG4105CJN penicillin-binding protein FDF39_12340 ENOG4105CSM endonuclease III FDF39_12345 ENOG4108R3D Electron transport complex FDF39_12350 ENOG4105D82 Glutamate dehydrogenase FDF39_12360 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FDF39_12380 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FDF39_12585 ENOG4105DIJ Phosphoethanolamine transferase FDF39_12620 ENOG4105D0A hydroxylase FDF39_12625 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FDF39_12645 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FDF39_12650 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) FDF39_12660 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FDF39_12670 ENOG4105W4M Transport-associated protein FDF39_12680 ENOG4105E09 nadh pyrophosphatase FDF39_12690 ENOG4107RZZ dna polymerase iii epsilon subunit FDF39_12705 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FDF39_12710 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FDF39_12715 ENOG4108JQ5 ABC transporter FDF39_12735 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) FDF39_12755 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_12770 ENOG4105M4H endoribonuclease L-psp FDF39_12780 ENOG4105CR8 Transcriptional regulator FDF39_12800 ENOG4105D01 (LipO)protein FDF39_12860 ENOG4106B0W Curli production assembly transport component CsgG FDF39_12870 ENOG4107Y60 (LipO)protein FDF39_12880 ENOG4105C85 amino acid FDF39_12890 ENOG4105CUB amino acid FDF39_12910 ENOG4105C26 Dehydrogenase FDF39_12980 ENOG4105DD5 Flagellar motor switch protein FDF39_13005 ENOG4105F9F transposase FDF39_13015 ENOG4105NI3 Protein of unknown function (DUF3237) FDF39_13020 ENOG4105EPF Outer membrane porin FDF39_13025 ENOG4105C1G acyl-Coa dehydrogenase FDF39_13040 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase FDF39_13045 ENOG4108SC4 )-transporter FDF39_13060 ENOG4105E3J oxidoreductase FDF39_13075 ENOG4105E6M Sulphatase-modifying factor protein FDF39_13080 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FDF39_13085 ENOG4105D2S major facilitator superfamily FDF39_13090 ENOG4105EPF Outer membrane porin FDF39_13120 ENOG4105JQZ Methyltransferase FDF39_13125 ENOG4105F95 Monooxygenase FDF39_13160 ENOG4105F95 Monooxygenase FDF39_13170 ENOG4105C7N Xanthine uracil vitamin C permease FDF39_13175 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FDF39_13180 ENOG4105CPW cytochrome b561 FDF39_13190 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FDF39_13200 ENOG4105CFH Aspartokinase FDF39_13515 ENOG4105DR5 peptidase FDF39_13595 ENOG4105DFP Integrase FDF39_13605 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FDF39_13615 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FDF39_13630 ENOG4105CPC Aldo Keto reductase FDF39_13640 ENOG4108UKZ OsmC family FDF39_13660 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDF39_13690 ENOG4105CD3 dihydroorotase FDF39_13695 ENOG4108ZG0 Ompa motb domain protein FDF39_13705 ENOG4108TGY Glutathione S-transferase FDF39_13725 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FDF39_13735 ENOG4108K3A Glutathione S-transferase FDF39_13755 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FDF39_13765 ENOG4105D3R alkyl hydroperoxide reductase FDF39_13770 ENOG4105CQ7 ATP-dependent helicase FDF39_13785 ENOG4105D2S major facilitator superfamily FDF39_13790 ENOG4105DKK Benzoate FDF39_13795 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase FDF39_13805 ENOG4108UKV benzoate 1,2-dioxygenase FDF39_13810 ENOG4105FUY alpha subunit FDF39_13815 ENOG4108KB2 LysR family Transcriptional regulator FDF39_13870 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FDF39_13900 ENOG410829K Lysine exporter protein (Lyse ygga) FDF39_13905 ENOG4105VEQ Cold shock protein FDF39_13915 ENOG4105II7 pyrroline-5-carboxylate reductase FDF39_13950 ENOG4107YPT transcriptional regulator FDF39_13990 ENOG4105C2X Arabinose 5-phosphate isomerase FDF39_13995 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FDF39_14005 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FDF39_14010 ENOG4108IUZ ABC transporter FDF39_14055 ENOG4108Z4U Ferredoxin FDF39_14075 ENOG4107AQZ Membrane FDF39_14080 ENOG4105BZU Histidine kinase FDF39_14085 ENOG4105D1S lipid A biosynthesis FDF39_14100 ENOG4105D2S major facilitator superfamily FDF39_14120 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FDF39_14150 ENOG4108WAV Transcriptional regulator FDF39_14155 ENOG4105C5A transporter FDF39_14175 ENOG4108JIK carboxylase FDF39_14180 ENOG4107R4J Chloride channel FDF39_14195 ENOG4105R8C Transcriptional regulator FDF39_14205 ENOG4105E2A Dehydrogenase FDF39_14220 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FDF39_14225 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF FDF39_14245 ENOG4105MRR Transcriptional regulator (By similarity) FDF39_14255 ENOG4108HW3 (ABC) transporter FDF39_14375 ENOG4105UYK outer membrane protein a FDF39_14385 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDF39_14415 ENOG4105EMY transcriptional regulator FDF39_14425 ENOG4107Y2X deaminase FDF39_14430 ENOG4105DJ2 Major Facilitator Superfamily FDF39_14450 ENOG4105WPN DNA integration recombination invertion protein FDF39_14460 ENOG4108Z4X TRANSCRIPTIONal FDF39_14475 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDF39_14520 ENOG4105CZJ Aldehyde dehydrogenase FDF39_14525 ENOG4107QTZ amino acid FDF39_14530 ENOG4105EJQ L-serine dehydratase FDF39_14535 ENOG4105DXM phenylacetic acid degradation protein FDF39_14540 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FDF39_14545 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FDF39_14550 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FDF39_14555 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FDF39_14560 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDF39_14565 ENOG4105E39 Enoyl-CoA hydratase FDF39_14570 ENOG4108UKI Enoyl-CoA hydratase FDF39_14575 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FDF39_14580 ENOG4105CHU acetyl-coa acetyltransferase FDF39_14585 ENOG4105DZS Phenylacetate-CoA ligase FDF39_14590 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FDF39_14645 ENOG4107VGR Catalase FDF39_14650 ENOG4105CPW cytochrome b561 FDF39_14655 ENOG4105HEI LysR family (Transcriptional regulator FDF39_14665 ENOG4107HP6 Transcriptional regulator FDF39_14685 ENOG4105C4Y ABC transporter FDF39_14690 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDF39_14695 ENOG4107RCV ABC transporter, permease FDF39_14705 ENOG4107STF Involved in phosphonate degradation (By similarity) FDF39_14710 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FDF39_14715 ENOG4107RGD Major Facilitator superfamily FDF39_14720 ENOG4105C1G acyl-Coa dehydrogenase FDF39_14735 ENOG4108UKI Enoyl-CoA hydratase FDF39_14740 ENOG4105EA8 2-Nitropropane dioxygenase FDF39_14745 ENOG4105EQ0 Major Facilitator superfamily FDF39_14760 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FDF39_14765 ENOG4108R85 Short chain dehydrogenase FDF39_14770 ENOG4105E39 Enoyl-CoA hydratase FDF39_14775 ENOG4105C1G acyl-Coa dehydrogenase FDF39_14780 ENOG4107RGD Major Facilitator superfamily FDF39_14785 ENOG4107QP7 CoA-transferase subunit A FDF39_14790 ENOG4107QNJ CoA-transferase subunit B FDF39_14800 ENOG4105EQ0 Major Facilitator superfamily FDF39_14810 ENOG4105CSU acyl-Coa dehydrogenase FDF39_14825 ENOG4105CC0 LysR family Transcriptional regulator FDF39_14840 ENOG4105E39 Enoyl-CoA hydratase FDF39_14845 ENOG4107QX3 carboxylase FDF39_14850 ENOG4105C1G acyl-Coa dehydrogenase FDF39_14855 ENOG4105R8C Transcriptional regulator FDF39_14860 ENOG4105CEY Amp-dependent synthetase and ligase FDF39_14880 ENOG4105HEI LysR family (Transcriptional regulator FDF39_14925 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FDF39_14945 ENOG4105KT5 UmuD protein FDF39_14955 ENOG4105EW9 transcriptional regulator AsnC family FDF39_14965 ENOG4105BZU Histidine kinase FDF39_14970 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FDF39_14985 ENOG4105EAD ABC transporter FDF39_14990 ENOG4108HW4 amino acid AbC transporter FDF39_14995 ENOG4105CDA abc transporter atp-binding protein FDF39_15000 ENOG4107RP9 extracellular solute-binding protein, family 3 FDF39_15005 ENOG4105CT1 (ABC) transporter FDF39_15010 ENOG4105EXG Transcriptional regulator FDF39_15020 ENOG4105C9B Cysteine desulfurase FDF39_15025 ENOG4105ESN nucleotide-binding protein FDF39_15030 ENOG4105D7W serine acetyltransferase FDF39_15040 ENOG4105CHR reductase FDF39_15045 ENOG4105CBN LysR family transcriptional regulator FDF39_15050 ENOG4105CYM Glutathione S-transferase FDF39_15055 ENOG4108SHQ Glutathione S-transferase FDF39_15060 ENOG4105CMU LysR family (Transcriptional regulator FDF39_15065 ENOG4105VAW lrga family FDF39_15070 ENOG41067MG lrgb family FDF39_15075 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDF39_15090 ENOG4105DXI Major Facilitator superfamily FDF39_15100 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FDF39_15105 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) FDF39_15120 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase FDF39_15125 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FDF39_15140 ENOG4108K70 Transcriptional regulator FDF39_15145 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDF39_15155 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDF39_15160 ENOG4105C4M (Ubiquinol oxidase) subunit I FDF39_15185 ENOG4105C54 Major Facilitator superfamily FDF39_15195 ENOG4106FTQ Taurine ABC transporter, periplasmic FDF39_15200 ENOG4108IY8 ABC, transporter FDF39_15205 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FDF39_15210 ENOG4105E2B Taurine dioxygenase FDF39_15220 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FDF39_15230 ENOG4105CBN LysR family transcriptional regulator FDF39_15240 ENOG4105CPN adenine deaminase FDF39_15255 ENOG41082YX Transcriptional regulator, arsr family FDF39_15260 ENOG4105D6J arsenicaL-resistance protein FDF39_15265 ENOG4108KB2 LysR family Transcriptional regulator FDF39_15280 ENOG4108JU3 Alkyl hydroperoxide reductase FDF39_15305 ENOG4105C0B DNA polymerase III (alpha subunit) FDF39_15315 ENOG4105CK2 sodium dicarboxylate symporter FDF39_15320 ENOG4105CHM Aminotransferase FDF39_15330 ENOG4108V06 Glutathione peroxidase FDF39_15335 ENOG4105E7U AraC family transcriptional regulator FDF39_15365 ENOG4105ZED uncharacterized protein ygaH FDF39_15370 ENOG4108UMN azlc family FDF39_15395 ENOG4105C3G gtp-binding protein FDF39_15400 ENOG4108UMI ABC transporter, permease FDF39_15405 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FDF39_15410 ENOG4105D01 (LipO)protein FDF39_15415 ENOG4105D01 (LipO)protein FDF39_15430 ENOG4107T8P acyl-Coa dehydrogenase FDF39_15445 ENOG4105EAD ABC transporter FDF39_15450 ENOG4105DRP amino acid AbC transporter FDF39_15455 ENOG4105CDA abc transporter atp-binding protein FDF39_15465 ENOG4105EW9 transcriptional regulator AsnC family FDF39_15480 ENOG41067SE Tetr family transcriptional regulator FDF39_15510 ENOG4105ETS cytosine purines uracil thiamine allantoin FDF39_15520 ENOG4108IPJ Membrane FDF39_15550 ENOG4105GQR Chaperone FDF39_15555 ENOG4105X0I Fimbrial FDF39_15575 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FDF39_15580 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FDF39_15600 ENOG4108HWY Beta-lactamase FDF39_15625 ENOG4105CV1 Transketolase (EC 2.2.1.1) FDF39_15635 ENOG4108YYC ycei family FDF39_15645 ENOG4108T58 Mg2 transport protein CorA FDF39_15665 ENOG4105C26 Dehydrogenase FDF39_15670 ENOG4105EW9 transcriptional regulator AsnC family FDF39_15675 ENOG4105CK7 Sodium proline symporter FDF39_15680 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FDF39_15690 ENOG4108ZX5 transcriptional regulator FDF39_15700 ENOG4105BZ1 (ABC) transporter FDF39_15705 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FDF39_15710 ENOG4105XPP Protein of unknown function (DUF1275) FDF39_15720 ENOG41080HT Transcriptional regulator, arsr family FDF39_15730 ENOG4105EZE Cupin 4 family protein FDF39_15735 ENOG4108UHJ MAF-like protein FDF39_15755 ENOG4105D2N Aldolase FDF39_15760 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FDF39_15765 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FDF39_15770 ENOG4105EHM Aminoglycoside phosphotransferase FDF39_15775 ENOG4108S0S Nucleotidyl transferase FDF39_15785 ENOG4107QJE Chromosome Partitioning Protein FDF39_15790 ENOG4105FA0 parb-like partition protein FDF39_15805 ENOG4105BZ1 (ABC) transporter FDF39_15810 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FDF39_15820 ENOG4107QRG dna polymerase iii FDF39_15830 ENOG4105F8V Hydrolase, tatD family FDF39_15855 ENOG4108RTD type II secretion system protein K FDF39_15875 ENOG4108Z6B deaminase FDF39_15890 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FDF39_15895 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FDF39_15915 ENOG4107RN6 Monooxygenase FDF39_15925 ENOG4105D6Z AFG1 family ATPase FDF39_15930 ENOG4107QP3 malate synthase g FDF39_15940 ENOG4105SG9 biopolymer transport protein, ExbD FDF39_15975 ENOG4107QSI ABC, transporter FDF39_15980 ENOG4105DGW oligopeptidase A FDF39_16010 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FDF39_16025 ENOG4105K4T epimerase FDF39_16030 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) FDF39_16050 ENOG4108JA2 transcriptioN-repair coupling factor FDF39_16060 ENOG4105F8J Adenylate Guanylate cyclase FDF39_16065 ENOG4108ZIT Ferredoxin, 2FE-2S FDF39_16080 ENOG4108Z4V iron-sulfur cluster assembly FDF39_16085 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FDF39_16095 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family FDF39_16115 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FDF39_16120 ENOG4105E7U AraC family transcriptional regulator FDF39_16125 ENOG4105EEF Alkane 1-monooxygenase FDF39_16130 ENOG4105C1G acyl-Coa dehydrogenase FDF39_16135 ENOG4105C1G acyl-Coa dehydrogenase FDF39_16150 ENOG4108Z66 YbaK ebsC protein FDF39_16165 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDF39_16170 ENOG4105DUU IucA IucC family protein FDF39_16175 ENOG4105DJU Siderophore biosynthesis protein FDF39_16185 ENOG4105JSC dimethylmenaquinone methyltransferase FDF39_16220 ENOG4107VXZ Hydrolase FDF39_16230 ENOG4108YZT Adenosylcobinamide kinase FDF39_16235 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) FDF39_16240 ENOG4107TB6 phosphoglycerate mutase FDF39_16255 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDF39_16260 ENOG4107TSN permease FDF39_16280 ENOG4105CNM Receptor FDF39_16285 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FDF39_16300 ENOG4105CJ1 ABC, transporter FDF39_16305 ENOG4107QWP ABC-2 type transporter FDF39_16310 ENOG4107QWP ABC-2 type transporter FDF39_16335 ENOG4105K59 histidine triad (HIT) protein FDF39_16365 ENOG4105F2W methyltransferase FDF39_16385 ENOG4105C28 cystathionine FDF39_16400 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FDF39_16445 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FDF39_16450 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FDF39_16460 ENOG4105BZU Histidine kinase FDF39_16475 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FDF39_16480 ENOG4107R0V Pyruvate dehydrogenase FDF39_16485 ENOG4105CPP Dehydrogenase, E1 component FDF39_16500 ENOG4105CHR reductase FDF39_16510 ENOG4105FFC UPF0187 protein FDF39_16520 ENOG4107S76 domain protein FDF39_16530 ENOG4108VCT Sulfite exporter TauE/SafE FDF39_16545 ENOG4105UEI Transcriptional Regulator AraC Family FDF39_16550 ENOG4105KVH Transcriptional regulator FDF39_16555 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FDF39_16565 ENOG4105FDP GntR family transcriptional regulator FDF39_16580 ENOG4106FTQ Taurine ABC transporter, periplasmic FDF39_16585 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDF39_16605 ENOG4105CSH Transporter FDF39_16620 ENOG4108IJ0 Aspartate ammonia-lyase FDF39_16635 ENOG4107YNJ LysR family Transcriptional regulator FDF39_16645 ENOG4105CHU acetyl-coa acetyltransferase FDF39_16650 ENOG4105CRW Short chain fatty acid transporter FDF39_16665 ENOG4108M0I Transcriptional regulator FDF39_16675 ENOG4105CY2 Citrate transporter FDF39_16680 ENOG4105DTD Dehydrogenase FDF39_16690 ENOG4105D2S major facilitator superfamily FDF39_16710 ENOG4105CHR reductase FDF39_16735 ENOG4105F57 Anthranilate dioxygenase reductase FDF39_16740 ENOG4108YS2 small subunit FDF39_16745 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit FDF39_16750 ENOG4105F4R Transcriptional regulator mode FDF39_16755 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FDF39_16760 ENOG4105E0C molybdate abc transporter FDF39_16765 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FDF39_16770 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FDF39_16775 ENOG4105WQI isochorismatase FDF39_16785 ENOG4107T31 5'-nucleotidase FDF39_16820 ENOG4108IGT Dipeptidase FDF39_16840 ENOG4107RZC phospholipase d FDF39_16890 ENOG4105X0I Fimbrial FDF39_16920 ENOG4105CT3 Monooxygenase FDF39_16930 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDF39_16950 ENOG4108821 RND type efflux pump FDF39_16955 ENOG4108R6W Transcriptional regulator, ARAC family FDF39_16970 ENOG4105CHR reductase FDF39_16995 ENOG4105F9F transposase FDF39_17025 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FDF39_17095 ENOG4105E0A ABC, transporter FDF39_17100 ENOG4105EHG Permease protein FDF39_17110 ENOG4105DQ4 alcohol dehydrogenase FDF39_17120 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDF39_17130 ENOG4105EXW epimerase dehydratase FDF39_17135 ENOG4105DDW LysR family Transcriptional regulator FDF39_17145 ENOG4105C01 Dihydroxy-acid dehydratase FDF39_17150 ENOG4105CZJ Aldehyde dehydrogenase FDF39_17165 ENOG4105CW7 secretion protein, HlyD family FDF39_17200 ENOG4105CEY Amp-dependent synthetase and ligase FDF39_17210 ENOG4105CSU acyl-Coa dehydrogenase FDF39_17220 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr FDF39_17225 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FDF39_17230 ENOG41061TZ Short-chain dehydrogenase reductase Sdr FDF39_17240 ENOG4107Z3H Transcriptional regulator, TetR family FDF39_17280 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_17315 ENOG4107EJG GntR family transcriptional regulator FDF39_17325 ENOG4108KB2 LysR family Transcriptional regulator FDF39_17330 ENOG4105DTQ mandelate racemase muconate lactonizing FDF39_17335 ENOG4105NN7 muconolactone delta-isomerase FDF39_17345 ENOG4107QP7 CoA-transferase subunit A FDF39_17350 ENOG4107QNJ CoA-transferase subunit B FDF39_17355 ENOG4105CHU acetyl-coa acetyltransferase FDF39_17360 ENOG4105F2Z 3-oxoadipate enol-lactonase FDF39_17370 ENOG4105C26 Dehydrogenase FDF39_17380 ENOG4105F11 amine oxidase FDF39_17400 ENOG4105CHR reductase FDF39_17410 ENOG4105FUY alpha subunit FDF39_17430 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FDF39_17440 ENOG4105DNH Major Facilitator FDF39_17465 ENOG4105C1G acyl-Coa dehydrogenase FDF39_17470 ENOG4108PTX LysR family Transcriptional regulator FDF39_17475 ENOG4107HP6 Transcriptional regulator FDF39_17490 ENOG4105MD1 YeeE YedE family protein FDF39_17500 ENOG4105DZG Dehydrogenase FDF39_17505 ENOG4105TW1 Carbohydrate-selective porin OprB FDF39_17510 ENOG4106JPM 3-dehydroshikimate dehydratase FDF39_17515 ENOG4105FF2 Type I DHQase FDF39_17520 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha FDF39_17525 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta FDF39_17530 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FDF39_17535 ENOG4105D2S major facilitator superfamily FDF39_17540 ENOG4105F2Z 3-oxoadipate enol-lactonase FDF39_17545 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase FDF39_17550 ENOG4105CHU acetyl-coa acetyltransferase FDF39_17555 ENOG4107QNJ CoA-transferase subunit B FDF39_17560 ENOG4107QP7 CoA-transferase subunit A FDF39_17570 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FDF39_17575 ENOG4107VMU Membrane FDF39_17620 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDF39_17635 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDF39_17645 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDF39_17650 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FDF39_17680 ENOG4105C7B Threonine dehydratase FDF39_17690 ENOG4105CZN Potassium uptake protein FDF39_17695 ENOG4105HDD phospholipase FDF39_17705 ENOG4105E0K tonB-dependent siderophore receptor FDF39_17720 ENOG4105PV3 Inner membrane protein yqiJ FDF39_17730 ENOG4105C4M (Ubiquinol oxidase) subunit I FDF39_17735 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDF39_17755 ENOG41068P6 UPF0319 protein FDF39_17790 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FDF39_17795 ENOG4105C8Y Acetylornithine aminotransferase FDF39_17800 ENOG4105M2J Glutaredoxin FDF39_17810 ENOG4105CC0 LysR family Transcriptional regulator FDF39_17815 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FDF39_17820 ENOG4105CWM branched-chain amino acid transport system II carrier protein FDF39_17845 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FDF39_17850 ENOG4105DE4 1-phosphofructokinase FDF39_17855 ENOG4105DM4 PTS System FDF39_17870 ENOG4105BZU Histidine kinase FDF39_17880 ENOG4105D8V Glucose sorbosone dehydrogenase FDF39_17885 ENOG4108RAV Conserved protein FDF39_17890 ENOG4105CHH sulfate transporter FDF39_17910 ENOG4105C85 amino acid FDF39_17920 ENOG4105F7P transcriptional regulator AsnC family FDF39_17945 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FDF39_17950 ENOG4105VEJ Heat shock protein FDF39_17960 ENOG4105Y3E Modulates RecA activity (By similarity) FDF39_17975 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FDF39_17995 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FDF39_18010 ENOG4105KNE Phosphatidate cytidylyltransferase FDF39_18015 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FDF39_18040 ENOG4105CUX Signal transduction histidine kinase FDF39_18045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDF39_18105 ENOG4105CMR udp-glucose 4-epimerase FDF39_18110 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) FDF39_18130 ENOG4105T38 integral membrane protein FDF39_18135 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDF39_18145 ENOG4105CVM Molybdenum cofactor synthesis domain protein FDF39_18150 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FDF39_18185 ENOG4108IFG nitrite reductase, (NAD(P)H) FDF39_18190 ENOG4107QZF nitrite reductase NADPH large subunit FDF39_18200 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDF39_18220 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FDF39_18225 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FDF39_18235 ENOG4105D8G Major Facilitator superfamily FDF39_18270 ENOG4105E2A Dehydrogenase FDF39_18280 ENOG4105NVB glycoside hydrolase, family 19 FDF39_18580 ENOG4105CBC glutamate synthase FDF39_18620 ENOG4105C0A alcohol dehydrogenase FDF39_18630 ENOG4105HSS phospholipase C FDF39_18635 ENOG4107QMP dna polymerase iii subunits gamma and tau FDF39_18670 ENOG4105CHR reductase FDF39_18675 ENOG4105CHU acetyl-coa acetyltransferase FDF39_18690 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDF39_18695 ENOG4108NIW Leucine export protein LeuE FDF39_18700 ENOG4105EW9 transcriptional regulator AsnC family FDF39_18705 ENOG4105DKK Benzoate FDF39_18740 ENOG41081QV Universal stress protein FDF39_18745 ENOG4105C5H ABC transporter FDF39_18765 ENOG4105CNM Receptor FDF39_18795 ENOG4105CUY Mechanosensitive ion channel FDF39_18805 ENOG4105R8C Transcriptional regulator FDF39_18820 ENOG4105EW9 transcriptional regulator AsnC family FDF39_18825 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) FDF39_18855 ENOG4105CD8 aminopeptidase N FDF39_18880 ENOG4107QUV Domain protein FDF39_18885 ENOG4105C0A alcohol dehydrogenase FDF39_18895 ENOG4107RR1 TRANSCRIPTIONal FDF39_18905 ENOG4107R55 ethanolamine transporter FDF39_18910 ENOG4105CPD ethanolamine ammonia-lyase FDF39_18915 ENOG4107FQ9 ethanolamine ammonia-lyase FDF39_18920 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FDF39_18945 ENOG4108RCM Nitroreductase FDF39_18950 ENOG4108TZV Membrane FDF39_18955 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FDF39_18965 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FDF39_18970 ENOG4105K8N protein family UPF0079, ATPase FDF39_19005 ENOG4105DZ2 Transcriptional regulator FDF39_19050 ENOG4105K70 DNA-binding protein FDF39_19135 ENOG4108Z6H mu-like prophage Flumu protein gp27 FDF39_19140 ENOG4105CF2 Mu-like prophage FluMu protein GP28 FDF39_19155 ENOG4105QIB mu-like prophage Flumu protein gp29 FDF39_19165 ENOG4107XYH virion morphogenesis protein FDF39_19180 ENOG4105EFV Major head subunit FDF39_19280 ENOG4105F27 Major Facilitator FDF39_19285 ENOG4105EYW Ion transport protein FDF39_19295 ENOG4107QIJ Aconitate hydratase 2 FDF39_19315 ENOG4105CFU surface antigen FDF39_19320 ENOG4107S74 Lysophospholipid transporter LplT FDF39_19345 ENOG4105EEX Two component transcriptional regulator (Winged helix family FDF39_19355 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) FDF39_19360 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FDF39_19365 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FDF39_19385 ENOG4105D06 uba thif-type nad fad binding protein FDF39_19390 ENOG4108MEJ flavin reductase domain protein FDF39_19400 ENOG4105C1G acyl-Coa dehydrogenase FDF39_19415 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FDF39_19430 ENOG4105CC0 LysR family Transcriptional regulator FDF39_19460 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FDF39_19465 ENOG4105CND Glycosyl transferase, family 2 FDF39_19470 ENOG4107BJW polysaccharide deacetylase FDF39_19505 ENOG4105E2S oxidase) subunit II FDF39_19515 ENOG4105CCU oxidase (Subunit III) FDF39_19520 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FDF39_19545 ENOG4105CDU Replicative dna helicase FDF39_19550 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FDF39_19600 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FDF39_19605 ENOG4105DC1 bifunctional purine biosynthesis protein purh FDF39_19610 ENOG4105C12 Phosphoribosylglycinamide synthetase FDF39_19620 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FDF39_19625 ENOG4108UMI ABC transporter, permease FDF39_19630 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FDF39_19640 ENOG4105CK2 sodium dicarboxylate symporter FDF39_19690 ENOG4105ETX regulatoR FDF39_19695 ENOG4105DHQ Histidine kinase FDF39_19700 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FDF39_19710 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FDF39_19750 ENOG4105VT2 5-hydroxyisourate hydrolase FDF39_19760 ENOG4105DY2 Paraquat-inducible protein b FDF39_19765 ENOG4105F1S paraquat-inducible protein a FDF39_19935 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDF39_19940 ENOG4105BZS acriflavin resistance protein FDF39_19950 ENOG4105BZU Histidine kinase FDF39_19955 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDF39_20005 ENOG4108NE4 FDF39_20020 ENOG4107QJE Chromosome Partitioning Protein FDF39_20025 ENOG410636K Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)