locus-tag	class	description
FDF39_00005	COG1051	belongs to the nudix hydrolase family
FDF39_00010	COG2186	Transcriptional regulator
FDF39_00020	COG0786	glutamate:sodium symporter activity
FDF39_00025	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDF39_00050	COG3111	PFAM Bacterial OB fold (BOF) protein
FDF39_00145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDF39_00150	COG1610	YqeY-like protein
FDF39_00155	COG4783	chaperone-mediated protein folding
FDF39_00180	COG1286	toxin biosynthetic process
FDF39_00210	COG0778	Nitroreductase
FDF39_00220	COG0513	Belongs to the DEAD box helicase family
FDF39_00240	COG2363	Small membrane protein
FDF39_00270	COG4650	regulator
FDF39_00275	COG1234	tRNA 3'-trailer cleavage
FDF39_00280	COG1690	Belongs to the RtcB family
FDF39_00300	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDF39_00310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDF39_00325	COG1960	acyl-CoA dehydrogenase activity
FDF39_00330	COG1301	dicarboxylic acid transport
FDF39_00345	COG3139	Protein of unknown function (DUF1315)
FDF39_00350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDF39_00355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDF39_00365	COG0494	nUDIX hydrolase
FDF39_00375	COG0642	Histidine kinase
FDF39_00380	COG0745	RESPONSE REGULATOR receiver
FDF39_00410	COG1720	tRNA m6t6A37 methyltransferase activity
FDF39_00420	COG0384	phenazine biosynthesis protein PhzF
FDF39_00425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_00435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF39_00450	COG4160	amino acid transport
FDF39_00455	COG4215	(ABC) transporter
FDF39_00470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF39_00480	COG1538	Outer membrane efflux protein
FDF39_00520	COG1131	(ABC) transporter
FDF39_00525	COG0842	Transport permease protein
FDF39_00540	COG0772	Belongs to the SEDS family
FDF39_00545	COG2951	lytic endotransglycosylase activity
FDF39_00570	COG2207	Transcriptional regulator
FDF39_00585	COG0052	Belongs to the universal ribosomal protein uS2 family
FDF39_00590	COG0024	Methionine aminopeptidase
FDF39_00600	COG2223	nitrite transmembrane transporter activity
FDF39_00610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF39_00615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF39_00635	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDF39_00640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDF39_00665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF39_00670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDF39_00675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDF39_00710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDF39_00735	COG0512	Glutamine amidotransferase of anthranilate synthase
FDF39_00740	COG0308	aminopeptidase N
FDF39_00770	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDF39_00800	COG3739	integral membrane protein
FDF39_00815	COG1169	isochorismate synthase
FDF39_00825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FDF39_00830	COG5265	(ABC) transporter
FDF39_00835	COG1132	(ABC) transporter
FDF39_00850	COG1535	isochorismatase
FDF39_00850	COG3433	isochorismatase activity
FDF39_00855	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDF39_00860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF39_00875	COG4607	ABC-type enterochelin transport system periplasmic component
FDF39_00880	COG4604	ABC transporter, ATP-binding protein
FDF39_00885	COG4605	iron ion homeostasis
FDF39_00890	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDF39_00895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF39_00910	COG2964	Protein conserved in bacteria
FDF39_00925	COG1741	Belongs to the pirin family
FDF39_00970	COG2879	small protein
FDF39_00975	COG1966	Carbon starvation protein
FDF39_00995	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDF39_01020	COG1067	ATP-dependent peptidase activity
FDF39_01025	COG0583	DNA-binding transcription factor activity
FDF39_01050	COG1686	Belongs to the peptidase S11 family
FDF39_01055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDF39_01095	COG0616	signal peptide processing
FDF39_01100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDF39_01110	COG0573	inorganic phosphate transmembrane transporter activity
FDF39_01115	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDF39_01120	COG1113	amino acid transport
FDF39_01125	COG3961	Belongs to the TPP enzyme family
FDF39_01130	COG1522	sequence-specific DNA binding
FDF39_01140	COG0076	glutamate decarboxylase activity
FDF39_01145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF39_01155	COG1309	transcriptional regulator
FDF39_01170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF39_01205	COG0352	thiamine-phosphate diphosphorylase activity
FDF39_01230	COG0612	Peptidase, M16
FDF39_01245	COG0583	DNA-binding transcription factor activity
FDF39_01275	COG1187	pseudouridine synthase activity
FDF39_01290	COG1686	Belongs to the peptidase S11 family
FDF39_01295	COG1252	NADH dehydrogenase
FDF39_01305	COG0415	Belongs to the DNA photolyase family
FDF39_01320	COG1215	transferase activity, transferring glycosyl groups
FDF39_01405	COG0556	nucleotide-excision repair
FDF39_01435	COG0443	Heat shock 70 kDa protein
FDF39_01465	COG4221	oxidoreductase activity
FDF39_01475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDF39_01480	COG1381	Involved in DNA repair and RecF pathway recombination
FDF39_01490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDF39_01505	COG0681	Belongs to the peptidase S26 family
FDF39_01520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF39_01545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDF39_01550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FDF39_01560	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDF39_01565	COG4208	sulfate ABC transporter
FDF39_01570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDF39_01575	COG0583	DNA-binding transcription factor activity
FDF39_01580	COG4625	pathogenesis
FDF39_01595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDF39_01610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDF39_01625	COG1056	cytidyltransferase-related domain
FDF39_01625	COG1051	belongs to the nudix hydrolase family
FDF39_01630	COG1024	Enoyl-CoA hydratase
FDF39_01635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDF39_01640	COG2814	Major facilitator Superfamily
FDF39_01645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDF39_01645	COG0047	phosphoribosylformylglycinamidine synthase activity
FDF39_01665	COG1473	amidohydrolase
FDF39_01670	COG0824	Thioesterase
FDF39_01690	COG0823	Involved in the tonB-independent uptake of proteins
FDF39_01710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF39_01745	COG0628	permease
FDF39_01755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDF39_01760	COG0596	Alpha beta hydrolase
FDF39_01765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDF39_01765	COG0616	signal peptide processing
FDF39_01780	COG1136	(ABC) transporter
FDF39_01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF39_01835	COG0463	Glycosyl transferase, family 2
FDF39_01865	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDF39_01870	COG1280	lysine exporter protein (LysE YggA)
FDF39_01875	COG2267	carboxylic ester hydrolase activity
FDF39_01895	COG1113	amino acid transport
FDF39_01900	COG1115	amino acid carrier protein
FDF39_01915	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDF39_01925	COG3339	Conserved Protein
FDF39_01930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDF39_01935	COG0243	molybdopterin cofactor binding
FDF39_01955	COG0778	Nitroreductase
FDF39_01990	COG0210	DNA helicase
FDF39_02005	COG2132	Multicopper oxidase
FDF39_02020	COG2205	protein histidine kinase activity
FDF39_02025	COG2217	Heavy metal translocating P-type atpase
FDF39_02050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDF39_02075	COG0741	lytic transglycosylase activity
FDF39_02120	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF39_02140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDF39_02145	COG0477	Major facilitator Superfamily
FDF39_02195	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDF39_02205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF39_02230	COG0505	Belongs to the CarA family
FDF39_02245	COG1309	transcriptional regulator
FDF39_02250	COG0251	oxidation-reduction process
FDF39_02260	COG0589	response to stress
FDF39_02275	COG2843	Capsule synthesis protein
FDF39_02295	COG2321	neutral zinc metallopeptidase
FDF39_02300	COG2354	Protein conserved in bacteria
FDF39_02320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF39_02345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDF39_02350	COG1053	succinate dehydrogenase
FDF39_02355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDF39_02360	COG2009	succinate dehydrogenase
FDF39_02395	COG2921	Belongs to the UPF0250 family
FDF39_02400	COG0321	lipoyl(octanoyl) transferase activity
FDF39_02415	COG0531	amino acid
FDF39_02430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDF39_02435	COG1648	precorrin-2 dehydrogenase activity
FDF39_02435	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDF39_02450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDF39_02480	COG0671	phosphoesterase, PA-phosphatase related
FDF39_02485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF39_02495	COG1538	Outer membrane efflux protein
FDF39_02500	COG0393	Putative heavy-metal-binding
FDF39_02505	COG0393	Putative heavy-metal-binding
FDF39_02515	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_02525	COG0525	valine-tRNA ligase activity
FDF39_02530	COG2226	methyltransferase
FDF39_02545	COG0004	ammonium transporteR
FDF39_02555	COG0642	Histidine kinase
FDF39_02560	COG0745	RESPONSE REGULATOR receiver
FDF39_02565	COG2194	sulfuric ester hydrolase activity
FDF39_02600	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDF39_02615	COG2315	Protein conserved in bacteria
FDF39_02620	COG0142	geranyltranstransferase activity
FDF39_02625	COG2828	Protein conserved in bacteria
FDF39_02630	COG1113	amino acid transport
FDF39_02690	COG2207	Transcriptional regulator
FDF39_02715	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF39_02725	COG0560	Phosphoserine phosphatase
FDF39_02735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF39_02745	COG1530	ribonuclease E activity
FDF39_02750	COG0424	maF-like protein
FDF39_02755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDF39_02760	COG1792	Involved in formation and maintenance of cell shape
FDF39_02765	COG1077	Cell shape determining protein MreB Mrl
FDF39_02770	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF39_02780	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF39_02810	COG3590	peptidase
FDF39_02815	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDF39_02830	COG1115	amino acid carrier protein
FDF39_02850	COG2814	Major facilitator Superfamily
FDF39_02855	COG1289	transmembrane transporter activity
FDF39_02905	COG1376	ErfK ybiS ycfS ynhG family protein
FDF39_02910	COG2832	Protein of unknown function (DUF454)
FDF39_02920	COG5510	response to toxic substance
FDF39_02950	COG0840	transmembrane signaling receptor activity
FDF39_02990	COG3422	double-strand break repair
FDF39_02995	COG2824	Alkylphosphonate utilization operon protein PhnA
FDF39_03000	COG3189	MarR family transcriptional regulator
FDF39_03010	COG0354	folic acid binding
FDF39_03015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF39_03025	COG0679	Auxin Efflux Carrier
FDF39_03030	COG1902	pentaerythritol trinitrate reductase activity
FDF39_03035	COG4772	TonB-dependent receptor
FDF39_03040	COG2094	Belongs to the DNA glycosylase MPG family
FDF39_03070	COG2233	PERMEase
FDF39_03080	COG0833	amino acid
FDF39_03085	COG1690	Belongs to the RtcB family
FDF39_03090	COG2885	chlorophyll binding
FDF39_03090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDF39_03100	COG0183	Belongs to the thiolase family
FDF39_03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF39_03140	COG2207	Transcriptional regulator
FDF39_03145	COG0183	Belongs to the thiolase family
FDF39_03165	COG2153	protein acetylation
FDF39_03175	COG1272	protein, Hemolysin III
FDF39_03180	COG0477	Major facilitator Superfamily
FDF39_03195	COG0450	alkyl hydroperoxide reductase
FDF39_03215	COG0285	dihydrofolate synthase activity
FDF39_03250	COG0133	tryptophan synthase activity
FDF39_03260	COG4206	TonB-dependent receptor
FDF39_03265	COG2096	Adenosyltransferase
FDF39_03270	COG0584	glycerophosphoryl diester phosphodiesterase
FDF39_03285	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDF39_03290	COG0745	RESPONSE REGULATOR receiver
FDF39_03295	COG2205	protein histidine kinase activity
FDF39_03305	COG1960	acyl-CoA dehydrogenase activity
FDF39_03310	COG1960	acyl-CoA dehydrogenase activity
FDF39_03400	COG0438	transferase activity, transferring glycosyl groups
FDF39_03405	COG0463	Glycosyl transferase, family 2
FDF39_03410	COG0726	polysaccharide deacetylase
FDF39_03430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDF39_03435	COG2205	protein histidine kinase activity
FDF39_03470	COG1862	Preprotein translocase
FDF39_03480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDF39_03485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDF39_03495	COG3781	membrane
FDF39_03500	COG0613	PHP domain protein
FDF39_03510	COG2350	Protein conserved in bacteria
FDF39_03540	COG1607	acyl-coa hydrolase
FDF39_03555	COG3453	Protein conserved in bacteria
FDF39_03555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF39_03605	COG2199	diguanylate cyclase activity
FDF39_03615	COG1408	metallophosphoesterase
FDF39_03620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDF39_03630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDF39_03650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDF39_03655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDF39_03660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDF39_03670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDF39_03680	COG2969	positive regulation of protein catabolic process
FDF39_03700	COG1960	acyl-CoA dehydrogenase activity
FDF39_03745	COG1183	phosphatidylcholine synthase activity
FDF39_03750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDF39_03780	COG0739	heme binding
FDF39_03780	COG0741	lytic transglycosylase activity
FDF39_03780	COG1196	nuclear chromosome segregation
FDF39_03790	COG1702	phosphate starvation-inducible protein PhoH
FDF39_03825	COG1295	ribonuclease BN
FDF39_03830	COG0697	spore germination
FDF39_03835	COG2169	Transcriptional regulator
FDF39_03840	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDF39_03885	COG0557	exoribonuclease II activity
FDF39_03890	COG0339	signal peptide processing
FDF39_03895	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDF39_03925	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDF39_03930	COG1960	acyl-CoA dehydrogenase activity
FDF39_03955	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDF39_03965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDF39_04085	COG0626	cystathionine gamma-synthase activity
FDF39_04090	COG0433	COG0433 Predicted ATPase
FDF39_04095	COG1017	nitric oxide dioxygenase activity
FDF39_04095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF39_04100	COG1959	2 iron, 2 sulfur cluster binding
FDF39_04120	COG1946	Acyl-CoA thioesterase
FDF39_04140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDF39_04145	COG1040	competence protein
FDF39_04150	COG0494	nUDIX hydrolase
FDF39_04160	COG0598	Magnesium transport protein CorA
FDF39_04170	COG2854	intermembrane phospholipid transfer
FDF39_04180	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDF39_04185	COG1127	ABC transporter
FDF39_04195	COG0513	Belongs to the DEAD box helicase family
FDF39_04215	COG0408	coproporphyrinogen oxidase activity
FDF39_04240	COG1983	PspC domain protein
FDF39_04245	COG0517	IMP dehydrogenase activity
FDF39_04305	COG0583	DNA-binding transcription factor activity
FDF39_04345	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_04355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF39_04360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF39_04365	COG0833	amino acid
FDF39_04400	COG0628	permease
FDF39_04410	COG1289	transmembrane transporter activity
FDF39_04425	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF39_04430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDF39_04440	COG0277	FAD linked oxidase domain protein
FDF39_04445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDF39_04470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDF39_04475	COG5380	lipid catabolic process
FDF39_04495	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDF39_04555	COG0194	GDP metabolic process
FDF39_04565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF39_04585	COG3307	-O-antigen
FDF39_04605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDF39_04610	COG1704	LemA family
FDF39_04620	COG0493	'glutamate synthase
FDF39_04625	COG0067	glutamate synthase
FDF39_04625	COG0070	glutamate synthase
FDF39_04625	COG0069	glutamate synthase activity
FDF39_04675	COG2226	methyltransferase
FDF39_04690	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDF39_04695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDF39_04740	COG0833	amino acid
FDF39_04805	COG0488	(ABC) transporter
FDF39_04815	COG4221	oxidoreductase activity
FDF39_04820	COG0659	secondary active sulfate transmembrane transporter activity
FDF39_04830	COG0745	RESPONSE REGULATOR receiver
FDF39_04845	COG0427	acetyl-CoA hydrolase
FDF39_04875	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDF39_04895	COG1132	(ABC) transporter
FDF39_04910	COG2329	Antibiotic biosynthesis monooxygenase
FDF39_04925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDF39_04980	COG2207	Transcriptional regulator
FDF39_04990	COG1129	ABC transporter
FDF39_05015	COG0667	Aldo Keto reductase
FDF39_05065	COG0583	DNA-binding transcription factor activity
FDF39_05070	COG2814	Major facilitator Superfamily
FDF39_05100	COG1335	isochorismatase
FDF39_05110	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_05115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF39_05125	COG1113	amino acid transport
FDF39_05135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDF39_05150	COG2814	Major facilitator Superfamily
FDF39_05160	COG0352	thiamine-phosphate diphosphorylase activity
FDF39_05160	COG0351	phosphomethylpyrimidine kinase
FDF39_05160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF39_05180	COG1309	transcriptional regulator
FDF39_05185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDF39_05190	COG3706	GGDEF domain
FDF39_05200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF39_05210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF39_05215	COG3162	membrane
FDF39_05220	COG0784	Response regulator, receiver
FDF39_05220	COG2198	Histidine kinase
FDF39_05220	COG2205	protein histidine kinase activity
FDF39_05245	COG1522	sequence-specific DNA binding
FDF39_05250	COG1335	isochorismatase
FDF39_05255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF39_05265	COG0668	transmembrane transport
FDF39_05270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDF39_05280	COG1902	pentaerythritol trinitrate reductase activity
FDF39_05300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDF39_05325	COG0426	domain, Protein
FDF39_05325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF39_05330	COG4774	siderophore transport
FDF39_05335	COG2119	membrane
FDF39_05345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF39_05355	COG4942	peptidase
FDF39_05370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDF39_05380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDF39_05400	COG0189	ligase activity
FDF39_05420	COG0708	Exodeoxyribonuclease III
FDF39_05425	COG1393	Belongs to the ArsC family
FDF39_05440	COG3706	GGDEF domain
FDF39_05475	COG2351	hydroxyisourate hydrolase activity
FDF39_05480	COG2233	PERMEase
FDF39_05490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF39_05500	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDF39_05510	COG3150	esterase
FDF39_05540	COG3409	Peptidoglycan-binding domain 1 protein
FDF39_05540	COG1388	LysM domain
FDF39_05540	COG5632	N-Acetylmuramoyl-L-alanine amidase
FDF39_05545	COG3501	Rhs element vgr protein
FDF39_05555	COG2918	glutathione biosynthetic process
FDF39_05570	COG2733	membrane
FDF39_05575	COG0436	Aminotransferase
FDF39_05580	COG0534	Mate efflux family protein
FDF39_05670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDF39_05675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDF39_05685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDF39_05720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF39_05735	COG0010	Belongs to the arginase family
FDF39_05765	COG2188	Transcriptional regulator
FDF39_05775	COG0523	cobalamin synthesis protein
FDF39_05785	COG1113	amino acid transport
FDF39_05795	COG0625	glutathione transferase activity
FDF39_05820	COG0534	Mate efflux family protein
FDF39_05825	COG0385	Bile acid
FDF39_05830	COG1335	isochorismatase
FDF39_05835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF39_05855	COG2116	formate transmembrane transporter activity
FDF39_05860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDF39_05865	COG2133	pyrroloquinoline quinone binding
FDF39_05870	COG2983	Belongs to the UPF0260 family
FDF39_05890	COG1194	a g-specific adenine glycosylase
FDF39_05905	COG2818	Glycosylase
FDF39_05910	COG1064	alcohol dehydrogenase
FDF39_05915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_05935	COG0656	L-ascorbic acid biosynthetic process
FDF39_05940	COG2814	Major facilitator Superfamily
FDF39_05990	COG2233	PERMEase
FDF39_05995	COG0583	DNA-binding transcription factor activity
FDF39_06030	COG0733	neurotransmitter:sodium symporter activity
FDF39_06075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDF39_06080	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDF39_06085	COG0596	Alpha beta hydrolase
FDF39_06115	COG0488	(ABC) transporter
FDF39_06120	COG0586	Pfam SNARE associated Golgi protein
FDF39_06130	COG0187	DNA topoisomerase II activity
FDF39_06140	COG0592	DNA-directed DNA polymerase activity
FDF39_06150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FDF39_06165	COG0706	membrane insertase activity
FDF39_06180	COG1230	cation diffusion facilitator family transporter
FDF39_06185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF39_06200	COG0402	S-adenosylhomocysteine deaminase activity
FDF39_06210	COG0754	glutathionylspermidine amidase activity
FDF39_06220	COG0861	Integral membrane protein TerC family
FDF39_06225	COG0671	phosphoesterase, PA-phosphatase related
FDF39_06235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDF39_06255	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDF39_06260	COG2951	lytic endotransglycosylase activity
FDF39_06315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDF39_06355	COG1047	Peptidyl-prolyl cis-trans
FDF39_06365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDF39_06370	COG0196	riboflavin kinase activity
FDF39_06380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDF39_06385	COG1309	transcriptional regulator
FDF39_06390	COG1116	anion transmembrane transporter activity
FDF39_06395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF39_06400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF39_06405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF39_06410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF39_06430	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_06435	COG0546	phosphoglycolate phosphatase activity
FDF39_06490	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDF39_06495	COG0728	peptidoglycan biosynthetic process
FDF39_06525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDF39_06535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDF39_06540	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDF39_06545	COG2089	acid synthase
FDF39_06555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDF39_06560	COG1083	cytidylyl-transferase
FDF39_06565	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_06575	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_06610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDF39_06625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDF39_06640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDF39_06655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF39_06660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF39_06670	COG2186	Transcriptional regulator
FDF39_06680	COG0277	FAD linked oxidase domain protein
FDF39_06690	COG1802	Transcriptional regulator
FDF39_06705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDF39_06755	COG0564	pseudouridine synthase activity
FDF39_06780	COG1522	sequence-specific DNA binding
FDF39_06795	COG0251	oxidation-reduction process
FDF39_06800	COG1113	amino acid transport
FDF39_06805	COG1113	amino acid transport
FDF39_06825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF39_06830	COG1960	acyl-CoA dehydrogenase activity
FDF39_06835	COG1024	Enoyl-CoA hydratase
FDF39_06840	COG1024	Enoyl-CoA hydratase
FDF39_06845	COG0477	Major facilitator Superfamily
FDF39_06850	COG3916	Acyl-homoserine-lactone synthase
FDF39_06860	COG2197	response regulator
FDF39_06875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDF39_06875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDF39_06875	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FDF39_06875	COG3321	synthase
FDF39_06895	COG2267	carboxylic ester hydrolase activity
FDF39_06915	COG0271	Belongs to the BolA IbaG family
FDF39_06925	COG1192	Involved in chromosome partitioning
FDF39_06940	COG0586	Pfam SNARE associated Golgi protein
FDF39_06945	COG2259	Doxx family
FDF39_06950	COG4399	Belongs to the UPF0754 family
FDF39_06955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF39_06955	COG0519	Catalyzes the synthesis of GMP from XMP
FDF39_07000	COG0281	malic enzyme
FDF39_07010	COG2837	iron assimilation
FDF39_07015	COG1280	lysine exporter protein (LysE YggA)
FDF39_07020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDF39_07025	COG1121	(ABC) transporter
FDF39_07095	COG0386	Belongs to the glutathione peroxidase family
FDF39_07110	COG1309	transcriptional regulator
FDF39_07115	COG0697	spore germination
FDF39_07125	COG0758	DNA mediated transformation
FDF39_07160	COG1309	transcriptional regulator
FDF39_07195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDF39_07205	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDF39_07240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF39_07250	COG2814	Major facilitator Superfamily
FDF39_07260	COG1253	flavin adenine dinucleotide binding
FDF39_07265	COG3012	SEC-C Motif Domain Protein
FDF39_07270	COG2860	membrane
FDF39_07275	COG0477	Major facilitator Superfamily
FDF39_07285	COG0318	PFAM AMP-dependent synthetase and ligase
FDF39_07300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDF39_07315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF39_07320	COG0235	Class ii aldolase
FDF39_07325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_07330	COG0606	chelatase, subunit chli
FDF39_07375	COG0589	response to stress
FDF39_07380	COG0659	secondary active sulfate transmembrane transporter activity
FDF39_07395	COG1061	Type III restriction enzyme res subunit
FDF39_07420	COG0606	chelatase, subunit chli
FDF39_07430	COG0347	Belongs to the P(II) protein family
FDF39_07435	COG0004	ammonium transporteR
FDF39_07485	COG0795	lipopolysaccharide-transporting ATPase activity
FDF39_07490	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDF39_07495	COG0793	Belongs to the peptidase S41A family
FDF39_07510	COG2197	response regulator
FDF39_07520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDF39_07530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF39_07535	COG4974	Belongs to the 'phage' integrase family
FDF39_07560	COG0772	Belongs to the SEDS family
FDF39_07565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDF39_07570	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDF39_07575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF39_07600	COG0697	spore germination
FDF39_07605	COG1538	Outer membrane efflux protein
FDF39_07625	COG3275	phosphorelay sensor kinase activity
FDF39_07635	COG0181	hydroxymethylbilane synthase activity
FDF39_07680	COG1716	ATPase activity
FDF39_07685	COG0546	phosphoglycolate phosphatase activity
FDF39_07780	COG0596	Alpha beta hydrolase
FDF39_07785	COG2056	Na+-H+ antiporter family
FDF39_07800	COG0326	Molecular chaperone. Has ATPase activity
FDF39_07815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDF39_07880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDF39_07885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF39_07885	COG2169	Transcriptional regulator
FDF39_07915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDF39_07925	COG0497	DNA recombination
FDF39_07940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF39_08000	COG0195	Participates in both transcription termination and antitermination
FDF39_08020	COG2212	antiporter activity
FDF39_08030	COG0651	ATP synthesis coupled electron transport
FDF39_08035	COG1006	Multisubunit Na H antiporter MnhC subunit
FDF39_08040	COG2111	Na H antiporter
FDF39_08040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF39_08055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDF39_08060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF39_08075	COG2226	methyltransferase
FDF39_08095	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDF39_08100	COG1074	ATP-dependent DNA helicase activity
FDF39_08125	COG0598	Magnesium transport protein CorA
FDF39_08130	COG0789	Transcriptional regulator
FDF39_08135	COG0484	heat shock protein binding
FDF39_08150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDF39_08150	COG0475	glutathione-regulated potassium exporter activity
FDF39_08175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF39_08180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FDF39_08185	COG4535	Mg2 and Co2 transporter CorC
FDF39_08190	COG0425	Belongs to the sulfur carrier protein TusA family
FDF39_08200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDF39_08200	COG0644	oxidoreductase
FDF39_08210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF39_08225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF39_08230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDF39_08270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDF39_08285	COG0534	Mate efflux family protein
FDF39_08295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDF39_08315	COG0583	DNA-binding transcription factor activity
FDF39_08335	COG1530	ribonuclease E activity
FDF39_08350	COG0546	phosphoglycolate phosphatase activity
FDF39_08355	COG2378	regulation of single-species biofilm formation
FDF39_08360	COG0625	glutathione transferase activity
FDF39_08370	COG0583	DNA-binding transcription factor activity
FDF39_08435	COG0473	3-isopropylmalate dehydrogenase activity
FDF39_08495	COG1301	dicarboxylic acid transport
FDF39_08505	COG1560	Kdo2-lipid A biosynthetic process
FDF39_08510	COG1280	lysine exporter protein (LysE YggA)
FDF39_08535	COG1733	regulation of RNA biosynthetic process
FDF39_08560	COG0210	DNA helicase
FDF39_08565	COG0724	RNA recognition motif
FDF39_08590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FDF39_08595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDF39_08610	COG0788	formyltetrahydrofolate deformylase activity
FDF39_08715	COG2813	Specifically methylates the guanine in position
FDF39_08715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF39_08725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDF39_08755	COG0740	serine-type endopeptidase activity
FDF39_08775	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF39_08775	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF39_08780	COG0857	belongs to the CobB CobQ family
FDF39_08780	COG0280	phosphate acetyltransferase
FDF39_08785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDF39_08795	COG0800	Aldolase
FDF39_08805	COG3265	gluconokinase activity
FDF39_08810	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_08820	COG2267	carboxylic ester hydrolase activity
FDF39_08835	COG0793	Belongs to the peptidase S41A family
FDF39_08870	COG1426	Protein conserved in bacteria
FDF39_08910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDF39_08925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDF39_08940	COG1538	Outer membrane efflux protein
FDF39_08945	COG1136	(ABC) transporter
FDF39_08945	COG0577	efflux transmembrane transporter activity
FDF39_08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF39_08975	COG0028	Belongs to the TPP enzyme family
FDF39_08980	COG0440	acetolactate synthase activity
FDF39_09040	COG4221	oxidoreductase activity
FDF39_09045	COG0583	DNA-binding transcription factor activity
FDF39_09050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDF39_09055	COG3321	synthase
FDF39_09055	COG0604	alcohol dehydrogenase
FDF39_09070	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FDF39_09085	COG1979	alcohol dehydrogenase
FDF39_09095	COG1902	pentaerythritol trinitrate reductase activity
FDF39_09105	COG1309	transcriptional regulator
FDF39_09110	COG2130	NADP-dependent
FDF39_09135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDF39_09150	COG0084	hydrolase, TatD family'
FDF39_09160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDF39_09170	COG0583	DNA-binding transcription factor activity
FDF39_09180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF39_09185	COG2814	Major facilitator Superfamily
FDF39_09195	COG0697	spore germination
FDF39_09200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDF39_09205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDF39_09210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FDF39_09225	COG3622	Belongs to the hyi family
FDF39_09230	COG2084	Dehydrogenase
FDF39_09235	COG1024	Enoyl-CoA hydratase
FDF39_09240	COG2205	protein histidine kinase activity
FDF39_09240	COG5002	protein histidine kinase activity
FDF39_09240	COG0784	Response regulator, receiver
FDF39_09260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF39_09270	COG3956	TIGRFAM MazG family protein
FDF39_09275	COG1555	photosystem II stabilization
FDF39_09280	COG0617	tRNA 3'-terminal CCA addition
FDF39_09285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDF39_09305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF39_09310	COG3028	Belongs to the UPF0307 family
FDF39_09315	COG0318	PFAM AMP-dependent synthetase and ligase
FDF39_09335	COG0625	glutathione transferase activity
FDF39_09340	COG1238	metal cluster binding
FDF39_09355	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FDF39_09420	COG0037	tRNA processing
FDF39_09460	COG1764	response to oxidative stress
FDF39_09475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF39_09535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDF39_09540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDF39_09545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDF39_09555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDF39_09590	COG1214	PFAM Peptidase M22, glycoprotease
FDF39_09605	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FDF39_09615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDF39_09620	COG0561	phosphatase activity
FDF39_09630	COG2132	Multicopper oxidase
FDF39_09635	COG3667	copper resistance
FDF39_09685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF39_09690	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDF39_09695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDF39_09725	COG0583	DNA-binding transcription factor activity
FDF39_09730	COG1960	acyl-CoA dehydrogenase activity
FDF39_09735	COG2814	Major facilitator Superfamily
FDF39_09740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDF39_09750	COG1053	succinate dehydrogenase
FDF39_09755	COG0583	DNA-binding transcription factor activity
FDF39_09775	COG0583	DNA-binding transcription factor activity
FDF39_09805	COG0583	DNA-binding transcription factor activity
FDF39_09815	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDF39_09820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF39_09840	COG0384	phenazine biosynthesis protein PhzF
FDF39_09850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDF39_09870	COG0745	RESPONSE REGULATOR receiver
FDF39_09875	COG2205	protein histidine kinase activity
FDF39_09910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDF39_09940	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF39_09945	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDF39_09965	COG0583	DNA-binding transcription factor activity
FDF39_09985	COG0668	transmembrane transport
FDF39_09995	COG2081	HI0933 family
FDF39_10030	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF39_10030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF39_10040	COG0489	protein tyrosine kinase activity
FDF39_10100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF39_10110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDF39_10125	COG0730	response to heat
FDF39_10135	COG1196	nuclear chromosome segregation
FDF39_10155	COG2223	nitrite transmembrane transporter activity
FDF39_10160	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDF39_10165	COG1877	trehalose-phosphatase activity
FDF39_10170	COG2226	methyltransferase
FDF39_10170	COG0596	Alpha beta hydrolase
FDF39_10170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF39_10185	COG4106	trans-aconitate 2-methyltransferase activity
FDF39_10200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDF39_10205	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDF39_10210	COG0009	L-threonylcarbamoyladenylate synthase
FDF39_10215	COG3101	peptidyl-lysine hydroxylation
FDF39_10220	COG1399	metal-binding, possibly nucleic acid-binding protein
FDF39_10245	COG1652	LysM domain
FDF39_10250	COG0352	thiamine-phosphate diphosphorylase activity
FDF39_10250	COG0351	phosphomethylpyrimidine kinase
FDF39_10250	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF39_10260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDF39_10300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDF39_10330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDF39_10345	COG0358	DNA primase activity
FDF39_10355	COG0564	pseudouridine synthase activity
FDF39_10420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF39_10480	COG0305	Participates in initiation and elongation during chromosome replication
FDF39_10590	COG5410	chromosome segregation
FDF39_10740	COG0582	viral genome integration into host DNA
FDF39_10750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF39_10770	COG0583	DNA-binding transcription factor activity
FDF39_10775	COG0473	3-isopropylmalate dehydrogenase activity
FDF39_10795	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_10815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF39_10815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDF39_10875	COG0456	acetyltransferase
FDF39_10885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDF39_10890	COG0492	ferredoxin-NADP+ reductase activity
FDF39_10895	COG1674	ftsk spoiiie
FDF39_10895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDF39_10900	COG1280	lysine exporter protein (LysE YggA)
FDF39_10915	COG2894	cell division
FDF39_10930	COG0204	Acyl-transferase
FDF39_10935	COG2885	chlorophyll binding
FDF39_10940	COG0210	DNA helicase
FDF39_10950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF39_10965	COG0121	glutamine amidotransferase
FDF39_10990	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDF39_10995	COG0735	belongs to the Fur family
FDF39_11040	COG1090	epimerase
FDF39_11055	COG2050	protein possibly involved in aromatic compounds catabolism
FDF39_11065	COG2814	Major facilitator Superfamily
FDF39_11070	COG0405	Gamma-glutamyltransferase
FDF39_11135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF39_11225	COG1484	DNA-dependent DNA replication
FDF39_11420	COG2026	Addiction module toxin, RelE StbE family
FDF39_11460	COG0592	DNA-directed DNA polymerase activity
FDF39_11555	COG0582	viral genome integration into host DNA
FDF39_11600	COG0629	single-stranded DNA binding
FDF39_11690	COG3179	chitinase
FDF39_11760	COG0477	Major facilitator Superfamily
FDF39_11765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF39_11775	COG1595	DNA-templated transcription, initiation
FDF39_11835	COG2040	homocysteine
FDF39_11860	COG1309	transcriptional regulator
FDF39_11865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF39_11870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF39_11880	COG1607	acyl-coa hydrolase
FDF39_11890	COG0523	cobalamin synthesis protein
FDF39_11900	COG4681	YaeQ
FDF39_11915	COG1215	transferase activity, transferring glycosyl groups
FDF39_11925	COG1024	Enoyl-CoA hydratase
FDF39_11940	COG1414	Transcriptional regulator
FDF39_11960	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_11975	COG2271	Major facilitator Superfamily
FDF39_11985	COG2267	carboxylic ester hydrolase activity
FDF39_11990	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_12005	COG0028	Belongs to the TPP enzyme family
FDF39_12015	COG0477	Major facilitator Superfamily
FDF39_12020	COG0242	peptide deformylase activity
FDF39_12025	COG2066	Belongs to the glutaminase family
FDF39_12030	COG2207	Transcriptional regulator
FDF39_12035	COG2223	nitrite transmembrane transporter activity
FDF39_12070	COG0306	phosphate transporter
FDF39_12090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF39_12135	COG4181	ATPase activity
FDF39_12140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDF39_12170	COG0583	DNA-binding transcription factor activity
FDF39_12180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF39_12185	COG1773	rubredoxin
FDF39_12235	COG2851	Citrate transporter
FDF39_12245	COG1253	flavin adenine dinucleotide binding
FDF39_12285	COG0804	urea catabolic process
FDF39_12295	COG0830	nickel cation binding
FDF39_12310	COG0742	ribosomal rna small subunit methyltransferase
FDF39_12315	COG0768	penicillin binding
FDF39_12340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDF39_12345	COG2878	Part of a membrane complex involved in electron transport
FDF39_12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF39_12360	COG3384	dioxygenase
FDF39_12380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDF39_12585	COG2194	sulfuric ester hydrolase activity
FDF39_12620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF39_12625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF39_12645	COG1279	arginine transmembrane transporter activity
FDF39_12650	COG0583	DNA-binding transcription factor activity
FDF39_12690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF39_12705	COG4174	ABC transporter (Permease)
FDF39_12710	COG4239	(ABC) transporter, permease
FDF39_12715	COG4172	Belongs to the ABC transporter superfamily
FDF39_12735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF39_12745	COG3706	GGDEF domain
FDF39_12745	COG4251	negative regulation of phosphorylation
FDF39_12745	COG5001	Diguanylate cyclase
FDF39_12745	COG2203	Gaf domain
FDF39_12755	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF39_12755	COG1902	pentaerythritol trinitrate reductase activity
FDF39_12770	COG0251	oxidation-reduction process
FDF39_12780	COG0583	DNA-binding transcription factor activity
FDF39_12880	COG1113	amino acid transport
FDF39_12890	COG0531	amino acid
FDF39_12910	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_12980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FDF39_13005	COG2826	transposase and inactivated derivatives, IS30 family
FDF39_13025	COG1960	acyl-CoA dehydrogenase activity
FDF39_13035	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_13040	COG1024	Enoyl-CoA hydratase
FDF39_13045	COG2814	Major facilitator Superfamily
FDF39_13060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF39_13075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF39_13120	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDF39_13125	COG2072	flavoprotein involved in K transport
FDF39_13130	COG0300	oxidoreductase activity
FDF39_13140	COG1309	transcriptional regulator
FDF39_13145	COG1741	Belongs to the pirin family
FDF39_13160	COG2072	flavoprotein involved in K transport
FDF39_13170	COG2252	PERMEase
FDF39_13175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDF39_13180	COG3038	cytochrome b561
FDF39_13190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDF39_13515	COG0739	heme binding
FDF39_13595	COG0582	viral genome integration into host DNA
FDF39_13605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDF39_13615	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDF39_13630	COG0667	Aldo Keto reductase
FDF39_13640	COG1765	OsmC-like protein
FDF39_13695	COG2885	chlorophyll binding
FDF39_13705	COG0625	glutathione transferase activity
FDF39_13725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDF39_13755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDF39_13765	COG0450	alkyl hydroperoxide reductase
FDF39_13770	COG1643	Atp-dependent helicase
FDF39_13785	COG2814	Major facilitator Superfamily
FDF39_13790	COG3135	benzoate transporter
FDF39_13795	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_13805	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF39_13810	COG4638	Rieske (2fe-2S)
FDF39_13815	COG0583	DNA-binding transcription factor activity
FDF39_13870	COG1570	exodeoxyribonuclease VII activity
FDF39_13900	COG1280	lysine exporter protein (LysE YggA)
FDF39_13905	COG1278	Cold shock
FDF39_13945	COG2814	Major facilitator Superfamily
FDF39_13950	COG1733	regulation of RNA biosynthetic process
FDF39_13995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDF39_14005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDF39_14010	COG1137	ATPase activity
FDF39_14055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDF39_14070	COG1522	sequence-specific DNA binding
FDF39_14075	COG5006	permease, DMT superfamily
FDF39_14085	COG1560	Kdo2-lipid A biosynthetic process
FDF39_14100	COG2814	Major facilitator Superfamily
FDF39_14120	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF39_14150	COG0583	DNA-binding transcription factor activity
FDF39_14155	COG1914	H( )-stimulated, divalent metal cation uptake system
FDF39_14175	COG4770	biotin carboxylase activity
FDF39_14180	COG0038	chloride channel
FDF39_14195	COG1309	transcriptional regulator
FDF39_14205	COG1063	alcohol dehydrogenase
FDF39_14220	COG0439	Biotin carboxylase
FDF39_14225	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF39_14230	COG1733	regulation of RNA biosynthetic process
FDF39_14245	COG0864	Transcriptional regulator
FDF39_14255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF39_14375	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDF39_14375	COG2885	chlorophyll binding
FDF39_14415	COG0583	DNA-binding transcription factor activity
FDF39_14425	COG0590	tRNA wobble adenosine to inosine editing
FDF39_14430	COG2807	transmembrane transport
FDF39_14450	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDF39_14460	COG0789	Transcriptional regulator
FDF39_14475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF39_14520	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_14525	COG0531	amino acid
FDF39_14530	COG1760	l-serine dehydratase
FDF39_14535	COG2030	dehydratase
FDF39_14535	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_14540	COG3396	Phenylacetate-CoA oxygenase
FDF39_14545	COG3460	Phenylacetate-CoA oxygenase
FDF39_14550	COG3396	Phenylacetate-CoA oxygenase
FDF39_14555	COG2151	metal-sulfur cluster biosynthetic enzyme
FDF39_14560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF39_14565	COG1024	Enoyl-CoA hydratase
FDF39_14570	COG1024	Enoyl-CoA hydratase
FDF39_14575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF39_14580	COG0183	Belongs to the thiolase family
FDF39_14585	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDF39_14590	COG3327	negative regulation of DNA-templated transcription, initiation
FDF39_14645	COG0753	catalase activity
FDF39_14650	COG3038	cytochrome b561
FDF39_14655	COG0583	DNA-binding transcription factor activity
FDF39_14665	COG1414	Transcriptional regulator
FDF39_14685	COG1840	ABC-type Fe3 transport system, periplasmic component
FDF39_14690	COG3842	ATPase activity
FDF39_14705	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDF39_14710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDF39_14715	COG2814	Major facilitator Superfamily
FDF39_14720	COG1960	acyl-CoA dehydrogenase activity
FDF39_14735	COG1024	Enoyl-CoA hydratase
FDF39_14745	COG2814	Major facilitator Superfamily
FDF39_14760	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF39_14765	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_14770	COG1024	Enoyl-CoA hydratase
FDF39_14775	COG1960	acyl-CoA dehydrogenase activity
FDF39_14780	COG2814	Major facilitator Superfamily
FDF39_14785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF39_14790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF39_14800	COG2814	Major facilitator Superfamily
FDF39_14810	COG1960	acyl-CoA dehydrogenase activity
FDF39_14825	COG0583	DNA-binding transcription factor activity
FDF39_14840	COG1024	Enoyl-CoA hydratase
FDF39_14845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDF39_14850	COG1960	acyl-CoA dehydrogenase activity
FDF39_14855	COG1309	transcriptional regulator
FDF39_14860	COG0318	PFAM AMP-dependent synthetase and ligase
FDF39_14880	COG0583	DNA-binding transcription factor activity
FDF39_14925	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_14945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDF39_14965	COG0784	Response regulator, receiver
FDF39_14965	COG2205	protein histidine kinase activity
FDF39_14985	COG0765	amino acid transport
FDF39_14990	COG0765	amino acid transport
FDF39_14995	COG1126	abc transporter atp-binding protein
FDF39_15000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF39_15005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF39_15015	COG1280	lysine exporter protein (LysE YggA)
FDF39_15020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDF39_15025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF39_15030	COG1045	serine acetyltransferase
FDF39_15040	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_15045	COG0583	DNA-binding transcription factor activity
FDF39_15050	COG0625	glutathione transferase activity
FDF39_15055	COG0625	glutathione transferase activity
FDF39_15060	COG0583	DNA-binding transcription factor activity
FDF39_15070	COG1346	cytolysis
FDF39_15075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_15090	COG2814	Major facilitator Superfamily
FDF39_15100	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDF39_15105	COG3052	prosthetic group binding
FDF39_15125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDF39_15145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_15155	COG1294	oxidase, subunit
FDF39_15160	COG1271	oxidase subunit
FDF39_15185	COG0477	Major facilitator Superfamily
FDF39_15195	COG4521	taurine ABC transporter
FDF39_15200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDF39_15205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF39_15210	COG2175	clavaminate synthase activity
FDF39_15220	COG1953	Uracil, thiamine, allantoin
FDF39_15230	COG0583	DNA-binding transcription factor activity
FDF39_15240	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDF39_15255	COG0640	Transcriptional regulator
FDF39_15260	COG0798	PFAM Bile acid sodium symporter
FDF39_15265	COG0583	DNA-binding transcription factor activity
FDF39_15280	COG3634	alkyl hydroperoxide reductase activity
FDF39_15315	COG1301	dicarboxylic acid transport
FDF39_15320	COG0436	Aminotransferase
FDF39_15330	COG0386	Belongs to the glutathione peroxidase family
FDF39_15370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDF39_15395	COG0012	GTP binding
FDF39_15400	COG2011	ABC-type metal ion transport system permease component
FDF39_15405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF39_15415	COG1464	Belongs to the NlpA lipoprotein family
FDF39_15445	COG0765	amino acid transport
FDF39_15450	COG0765	amino acid transport
FDF39_15455	COG1126	abc transporter atp-binding protein
FDF39_15465	COG1522	sequence-specific DNA binding
FDF39_15480	COG1309	transcriptional regulator
FDF39_15510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDF39_15520	COG0697	spore germination
FDF39_15550	COG3121	Chaperone
FDF39_15555	COG3539	Fimbrial protein
FDF39_15580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDF39_15580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDF39_15625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDF39_15635	COG2353	YceI-like domain
FDF39_15645	COG3698	Phosphodiester glycosidase
FDF39_15665	COG0506	proline dehydrogenase activity
FDF39_15665	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF39_15665	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF39_15675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF39_15680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDF39_15700	COG1132	(ABC) transporter
FDF39_15705	COG3122	Protein conserved in bacteria
FDF39_15710	COG3619	membrane
FDF39_15720	COG0640	Transcriptional regulator
FDF39_15730	COG2850	peptidyl-arginine hydroxylation
FDF39_15735	COG0424	maF-like protein
FDF39_15755	COG0191	fructose-bisphosphate aldolase activity
FDF39_15760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF39_15775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDF39_15785	COG1192	Involved in chromosome partitioning
FDF39_15790	COG1475	DNA binding
FDF39_15795	COG0811	peptide transport
FDF39_15805	COG1132	(ABC) transporter
FDF39_15810	COG1663	tetraacyldisaccharide 4'-kinase activity
FDF39_15830	COG0084	hydrolase, TatD family'
FDF39_15845	COG2165	general secretion pathway protein
FDF39_15875	COG0590	tRNA wobble adenosine to inosine editing
FDF39_15895	COG0776	regulation of translation
FDF39_15925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDF39_15930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDF39_15975	COG4166	transmembrane transport
FDF39_15980	COG0339	signal peptide processing
FDF39_15985	COG0601	transmembrane transport
FDF39_16025	COG0702	epimerase
FDF39_16030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF39_16050	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDF39_16080	COG0316	Belongs to the HesB IscA family
FDF39_16085	COG0822	iron-sulfur transferase activity
FDF39_16115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF39_16120	COG2207	Transcriptional regulator
FDF39_16125	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDF39_16130	COG1960	acyl-CoA dehydrogenase activity
FDF39_16135	COG1960	acyl-CoA dehydrogenase activity
FDF39_16150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDF39_16165	COG2814	Major facilitator Superfamily
FDF39_16170	COG4264	IucA IucC family
FDF39_16175	COG4264	IucA IucC family
FDF39_16185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF39_16220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDF39_16235	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDF39_16240	COG0406	alpha-ribazole phosphatase activity
FDF39_16255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDF39_16260	COG0730	response to heat
FDF39_16280	COG4773	Receptor
FDF39_16285	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF39_16300	COG1131	(ABC) transporter
FDF39_16305	COG0842	Transport permease protein
FDF39_16310	COG0842	Transport permease protein
FDF39_16335	COG0537	adenosine 5'-monophosphoramidase activity
FDF39_16365	COG2226	methyltransferase
FDF39_16400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDF39_16435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF39_16445	COG0133	tryptophan synthase activity
FDF39_16460	COG3706	GGDEF domain
FDF39_16475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF39_16480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDF39_16485	COG0022	dehydrogenase e1 component
FDF39_16490	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF39_16495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF39_16505	COG1063	alcohol dehydrogenase
FDF39_16510	COG3781	membrane
FDF39_16520	COG3453	Protein conserved in bacteria
FDF39_16520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF39_16530	COG0730	response to heat
FDF39_16545	COG3708	Transcriptional regulator
FDF39_16545	COG2207	Transcriptional regulator
FDF39_16550	COG1733	regulation of RNA biosynthetic process
FDF39_16555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDF39_16580	COG4521	taurine ABC transporter
FDF39_16585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF39_16605	COG0477	Major facilitator Superfamily
FDF39_16620	COG1027	Aspartate ammonia-lyase
FDF39_16635	COG0583	DNA-binding transcription factor activity
FDF39_16640	COG0583	DNA-binding transcription factor activity
FDF39_16645	COG0183	Belongs to the thiolase family
FDF39_16650	COG2031	fatty acid transporter
FDF39_16665	COG0583	DNA-binding transcription factor activity
FDF39_16675	COG2610	gluconate transmembrane transporter activity
FDF39_16680	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_16710	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_16720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF39_16735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF39_16735	COG0543	2 iron, 2 sulfur cluster binding
FDF39_16740	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF39_16745	COG4638	Rieske (2fe-2S)
FDF39_16755	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDF39_16760	COG4149	molybdate abc transporter
FDF39_16765	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDF39_16770	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_16775	COG1535	isochorismatase
FDF39_16775	COG3433	isochorismatase activity
FDF39_16840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDF39_16855	COG0753	catalase activity
FDF39_16865	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDF39_16890	COG3539	Fimbrial protein
FDF39_16920	COG2072	flavoprotein involved in K transport
FDF39_16930	COG1538	Outer membrane efflux protein
FDF39_16955	COG2207	Transcriptional regulator
FDF39_16970	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_16995	COG2826	transposase and inactivated derivatives, IS30 family
FDF39_17025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDF39_17095	COG1120	ATPase activity
FDF39_17110	COG1064	alcohol dehydrogenase
FDF39_17120	COG2084	Dehydrogenase
FDF39_17130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDF39_17135	COG0583	DNA-binding transcription factor activity
FDF39_17145	COG0129	dihydroxy-acid dehydratase activity
FDF39_17150	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_17165	COG1566	PFAM secretion protein HlyD family protein
FDF39_17200	COG0318	PFAM AMP-dependent synthetase and ligase
FDF39_17210	COG1960	acyl-CoA dehydrogenase activity
FDF39_17220	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_17225	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_17230	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_17240	COG1309	transcriptional regulator
FDF39_17280	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF39_17280	COG1902	pentaerythritol trinitrate reductase activity
FDF39_17315	COG2186	Transcriptional regulator
FDF39_17325	COG0583	DNA-binding transcription factor activity
FDF39_17330	COG4948	Mandelate Racemase Muconate Lactonizing
FDF39_17335	COG4829	muconolactone delta-isomerase
FDF39_17345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF39_17350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF39_17355	COG0183	Belongs to the thiolase family
FDF39_17360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF39_17370	COG1012	belongs to the aldehyde dehydrogenase family
FDF39_17380	COG3733	amine oxidase
FDF39_17390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF39_17400	COG1028	Short-chain dehydrogenase reductase Sdr
FDF39_17410	COG4638	Rieske (2fe-2S)
FDF39_17430	COG0154	amidase activity
FDF39_17440	COG2814	Major facilitator Superfamily
FDF39_17465	COG1960	acyl-CoA dehydrogenase activity
FDF39_17470	COG0583	DNA-binding transcription factor activity
FDF39_17475	COG1414	Transcriptional regulator
FDF39_17490	COG2391	methyltransferase activity
FDF39_17500	COG4993	Dehydrogenase
FDF39_17505	COG3659	wide pore channel activity
FDF39_17510	COG3420	alginic acid biosynthetic process
FDF39_17515	COG0710	3-dehydroquinate dehydratase activity
FDF39_17520	COG3485	protocatechuate 3,4-dioxygenase
FDF39_17525	COG3485	protocatechuate 3,4-dioxygenase
FDF39_17530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDF39_17535	COG2271	Major facilitator Superfamily
FDF39_17540	COG0596	Alpha beta hydrolase
FDF39_17545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDF39_17550	COG0183	Belongs to the thiolase family
FDF39_17555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF39_17560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF39_17570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDF39_17575	COG2323	membrane
FDF39_17620	COG1902	pentaerythritol trinitrate reductase activity
FDF39_17620	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF39_17635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDF39_17645	COG0542	response to heat
FDF39_17650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDF39_17680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDF39_17685	COG0569	domain protein
FDF39_17690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDF39_17705	COG4774	siderophore transport
FDF39_17710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDF39_17720	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDF39_17735	COG1294	oxidase, subunit
FDF39_17740	COG4890	Cyd operon protein YbgT
FDF39_17755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDF39_17790	COG0517	IMP dehydrogenase activity
FDF39_17790	COG0516	GMP reductase activity
FDF39_17795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF39_17800	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDF39_17810	COG0583	DNA-binding transcription factor activity
FDF39_17815	COG0024	Methionine aminopeptidase
FDF39_17845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDF39_17845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF39_17850	COG1105	Belongs to the carbohydrate kinase PfkB family
FDF39_17855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF39_17855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF39_17855	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDF39_17870	COG5001	Diguanylate cyclase
FDF39_17870	COG3300	MHYT domain
FDF39_17885	COG2135	peptidase activity
FDF39_17890	COG0659	secondary active sulfate transmembrane transporter activity
FDF39_17910	COG1113	amino acid transport
FDF39_17920	COG1522	sequence-specific DNA binding
FDF39_17945	COG1011	Hydrolase
FDF39_17950	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDF39_17960	COG2137	regulation of response to DNA damage stimulus
FDF39_17975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF39_17995	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDF39_18010	COG0575	Belongs to the CDS family
FDF39_18015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDF39_18040	COG3852	Histidine kinase
FDF39_18045	COG2204	response regulator
FDF39_18105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF39_18110	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDF39_18130	COG0697	spore germination
FDF39_18135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF39_18145	COG0303	'Molybdopterin
FDF39_18150	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDF39_18150	COG0315	cyclic pyranopterin monophosphate synthase activity
FDF39_18165	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDF39_18170	COG0243	molybdopterin cofactor binding
FDF39_18180	COG0243	molybdopterin cofactor binding
FDF39_18185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF39_18190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF39_18190	COG2146	nitrite reductase [NAD(P)H] activity
FDF39_18200	COG0745	RESPONSE REGULATOR receiver
FDF39_18205	COG1116	anion transmembrane transporter activity
FDF39_18205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF39_18220	COG0511	ligase activity, forming carbon-carbon bonds
FDF39_18235	COG2814	Major facilitator Superfamily
FDF39_18265	COG3293	Transposase
FDF39_18270	COG1063	alcohol dehydrogenase
FDF39_18280	COG3179	chitinase
FDF39_18330	COG1598	PFAM Uncharacterised protein family UPF0150
FDF39_18425	COG5410	chromosome segregation
FDF39_18580	COG0069	glutamate synthase activity
FDF39_18620	COG1454	alcohol dehydrogenase
FDF39_18625	COG0824	Thioesterase
FDF39_18635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDF39_18675	COG0183	Belongs to the thiolase family
FDF39_18700	COG1522	sequence-specific DNA binding
FDF39_18705	COG3135	benzoate transporter
FDF39_18740	COG0589	response to stress
FDF39_18745	COG0488	(ABC) transporter
FDF39_18765	COG4773	Receptor
FDF39_18795	COG0668	transmembrane transport
FDF39_18805	COG1309	transcriptional regulator
FDF39_18825	COG1605	Chorismate mutase
FDF39_18855	COG0308	aminopeptidase N
FDF39_18880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDF39_18885	COG1454	alcohol dehydrogenase
FDF39_18905	COG0531	amino acid
FDF39_18910	COG4303	Ethanolamine ammonia lyase large subunit
FDF39_18915	COG4302	ethanolamine ammonia-lyase activity
FDF39_18920	COG0519	Catalyzes the synthesis of GMP from XMP
FDF39_18920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF39_18950	COG0697	spore germination
FDF39_18955	COG1923	regulation of RNA biosynthetic process
FDF39_18965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDF39_18970	COG0802	atpase or kinase
FDF39_18990	COG1187	pseudouridine synthase activity
FDF39_19005	COG0583	DNA-binding transcription factor activity
FDF39_19050	COG0776	regulation of translation
FDF39_19080	COG3267	Type II secretory pathway component ExeA
FDF39_19080	COG3409	Peptidoglycan-binding domain 1 protein
FDF39_19105	COG0681	Belongs to the peptidase S26 family
FDF39_19140	COG4373	Mu-like prophage FluMu protein gp28
FDF39_19155	COG4383	Mu-like prophage protein gp29
FDF39_19165	COG5005	Phage virion morphogenesis
FDF39_19180	COG4397	Mu-like prophage major head subunit gpT
FDF39_19280	COG2814	Major facilitator Superfamily
FDF39_19285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF39_19315	COG0729	surface antigen
FDF39_19345	COG0745	RESPONSE REGULATOR receiver
FDF39_19355	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FDF39_19360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDF39_19365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDF39_19390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF39_19395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF39_19400	COG1960	acyl-CoA dehydrogenase activity
FDF39_19430	COG0583	DNA-binding transcription factor activity
FDF39_19460	COG3658	cytochrome
FDF39_19465	COG1215	transferase activity, transferring glycosyl groups
FDF39_19470	COG0726	polysaccharide deacetylase
FDF39_19470	COG1649	PFAM Uncharacterised BCR, COG1649
FDF39_19505	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDF39_19520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDF39_19545	COG0305	Participates in initiation and elongation during chromosome replication
FDF39_19550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDF39_19560	COG1305	Transglutaminase-like
FDF39_19600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDF39_19605	COG0138	bifunctional purine biosynthesis protein purh
FDF39_19610	COG0151	Belongs to the GarS family
FDF39_19615	COG1464	Belongs to the NlpA lipoprotein family
FDF39_19620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF39_19625	COG2011	ABC-type metal ion transport system permease component
FDF39_19630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF39_19640	COG1301	dicarboxylic acid transport
FDF39_19670	COG1794	racemase activity, acting on amino acids and derivatives
FDF39_19690	COG0745	RESPONSE REGULATOR receiver
FDF39_19695	COG0642	Histidine kinase
FDF39_19700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDF39_19710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDF39_19750	COG2351	hydroxyisourate hydrolase activity
FDF39_19760	COG3008	intermembrane lipid transfer
FDF39_19760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDF39_19765	COG2995	paraquat-inducible protein a
FDF39_19825	COG2184	nucleotidyltransferase activity
FDF39_19890	COG3316	Transposase and inactivated derivatives
FDF39_19905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FDF39_19935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF39_19940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDF39_19950	COG5002	protein histidine kinase activity
FDF39_19955	COG0745	RESPONSE REGULATOR receiver
FDF39_19970	COG3316	Transposase and inactivated derivatives
FDF39_20020	COG1192	Involved in chromosome partitioning
FDF39_20025	COG1475	DNA binding