locus-tag	class	description
HBK89_00010	COG0592	DNA-directed DNA polymerase activity
HBK89_00020	COG0187	DNA topoisomerase II activity
HBK89_00030	COG0586	Pfam SNARE associated Golgi protein
HBK89_00035	COG0488	(ABC) transporter
HBK89_00060	COG0596	Alpha beta hydrolase
HBK89_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HBK89_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBK89_00110	COG1047	Peptidyl-prolyl cis-trans
HBK89_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBK89_00125	COG0196	riboflavin kinase activity
HBK89_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBK89_00140	COG1309	transcriptional regulator
HBK89_00145	COG1116	anion transmembrane transporter activity
HBK89_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBK89_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBK89_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBK89_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBK89_00185	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_00190	COG0546	phosphoglycolate phosphatase activity
HBK89_00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBK89_00250	COG0728	peptidoglycan biosynthetic process
HBK89_00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBK89_00290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HBK89_00295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBK89_00300	COG2089	acid synthase
HBK89_00310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBK89_00315	COG1083	cytidylyl-transferase
HBK89_00320	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_00330	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_00365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBK89_00380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBK89_00395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBK89_00410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBK89_00415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBK89_00425	COG2186	Transcriptional regulator
HBK89_00435	COG0277	FAD linked oxidase domain protein
HBK89_00440	COG1448	Aminotransferase
HBK89_00450	COG1802	Transcriptional regulator
HBK89_00465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBK89_00555	COG0564	pseudouridine synthase activity
HBK89_00595	COG0251	oxidation-reduction process
HBK89_00600	COG1113	amino acid transport
HBK89_00605	COG1113	amino acid transport
HBK89_00625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBK89_00630	COG1960	acyl-CoA dehydrogenase activity
HBK89_00635	COG1024	Enoyl-CoA hydratase
HBK89_00640	COG1024	Enoyl-CoA hydratase
HBK89_00645	COG0477	Major facilitator Superfamily
HBK89_00650	COG3916	Acyl-homoserine-lactone synthase
HBK89_00660	COG2197	response regulator
HBK89_00670	COG1960	acyl-CoA dehydrogenase activity
HBK89_00675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBK89_00675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBK89_00675	COG3321	synthase
HBK89_00675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBK89_00685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBK89_00700	COG2267	carboxylic ester hydrolase activity
HBK89_00755	COG2826	transposase and inactivated derivatives, IS30 family
HBK89_00775	COG0673	inositol 2-dehydrogenase activity
HBK89_00780	COG1324	tolerance protein
HBK89_00805	COG2826	transposase and inactivated derivatives, IS30 family
HBK89_00840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBK89_00860	COG0659	secondary active sulfate transmembrane transporter activity
HBK89_00870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBK89_00875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBK89_00900	COG1570	exodeoxyribonuclease VII activity
HBK89_00915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBK89_00920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBK89_00925	COG2194	sulfuric ester hydrolase activity
HBK89_00930	COG0745	RESPONSE REGULATOR receiver
HBK89_00935	COG0642	Histidine kinase
HBK89_01030	COG3756	Protein conserved in bacteria
HBK89_01065	COG0271	Belongs to the BolA IbaG family
HBK89_01075	COG1192	Involved in chromosome partitioning
HBK89_01090	COG0586	Pfam SNARE associated Golgi protein
HBK89_01095	COG2259	Doxx family
HBK89_01100	COG4399	Belongs to the UPF0754 family
HBK89_01105	COG0519	Catalyzes the synthesis of GMP from XMP
HBK89_01105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBK89_01150	COG0281	malic enzyme
HBK89_01160	COG2837	iron assimilation
HBK89_01165	COG1280	lysine exporter protein (LysE YggA)
HBK89_01170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBK89_01175	COG1121	(ABC) transporter
HBK89_01240	COG0386	Belongs to the glutathione peroxidase family
HBK89_01255	COG1309	transcriptional regulator
HBK89_01260	COG0697	spore germination
HBK89_01270	COG0758	DNA mediated transformation
HBK89_01305	COG1309	transcriptional regulator
HBK89_01340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBK89_01350	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBK89_01385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBK89_01405	COG1253	flavin adenine dinucleotide binding
HBK89_01415	COG2860	membrane
HBK89_01420	COG0477	Major facilitator Superfamily
HBK89_01430	COG0318	PFAM AMP-dependent synthetase and ligase
HBK89_01445	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBK89_01460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBK89_01475	COG0606	chelatase, subunit chli
HBK89_01505	COG0589	response to stress
HBK89_01510	COG0659	secondary active sulfate transmembrane transporter activity
HBK89_01525	COG1061	Type III restriction enzyme res subunit
HBK89_01600	COG0606	chelatase, subunit chli
HBK89_01610	COG0347	Belongs to the P(II) protein family
HBK89_01615	COG0004	ammonium transporteR
HBK89_01625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBK89_01625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBK89_01665	COG0795	lipopolysaccharide-transporting ATPase activity
HBK89_01670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBK89_01675	COG0793	Belongs to the peptidase S41A family
HBK89_01690	COG2197	response regulator
HBK89_01700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBK89_01710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBK89_01715	COG4974	Belongs to the 'phage' integrase family
HBK89_01740	COG0772	Belongs to the SEDS family
HBK89_01745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBK89_01750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBK89_01755	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBK89_01780	COG0697	spore germination
HBK89_01785	COG1538	Outer membrane efflux protein
HBK89_01805	COG3275	phosphorelay sensor kinase activity
HBK89_01815	COG0181	hydroxymethylbilane synthase activity
HBK89_01860	COG1716	ATPase activity
HBK89_01865	COG0546	phosphoglycolate phosphatase activity
HBK89_01960	COG0596	Alpha beta hydrolase
HBK89_01965	COG2056	Na+-H+ antiporter family
HBK89_01980	COG0326	Molecular chaperone. Has ATPase activity
HBK89_01995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBK89_02060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBK89_02065	COG2169	Transcriptional regulator
HBK89_02065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBK89_02095	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBK89_02105	COG0497	DNA recombination
HBK89_02120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBK89_02130	COG0237	dephospho-CoA kinase activity
HBK89_02180	COG0195	Participates in both transcription termination and antitermination
HBK89_02200	COG2212	antiporter activity
HBK89_02210	COG0651	ATP synthesis coupled electron transport
HBK89_02215	COG1006	Multisubunit Na H antiporter MnhC subunit
HBK89_02220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBK89_02220	COG2111	Na H antiporter
HBK89_02235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBK89_02240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBK89_02255	COG2226	methyltransferase
HBK89_02275	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBK89_02280	COG1074	ATP-dependent DNA helicase activity
HBK89_02285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBK89_02310	COG0598	Magnesium transport protein CorA
HBK89_02315	COG0789	Transcriptional regulator
HBK89_02320	COG0484	heat shock protein binding
HBK89_02330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBK89_02335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBK89_02335	COG0475	glutathione-regulated potassium exporter activity
HBK89_02340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBK89_02360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBK89_02370	COG4535	Mg2 and Co2 transporter CorC
HBK89_02375	COG0425	Belongs to the sulfur carrier protein TusA family
HBK89_02380	COG0644	oxidoreductase
HBK89_02380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HBK89_02390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBK89_02405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBK89_02410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HBK89_02450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HBK89_02465	COG0534	Mate efflux family protein
HBK89_02475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBK89_02480	COG4221	oxidoreductase activity
HBK89_02485	COG0583	DNA-binding transcription factor activity
HBK89_02500	COG0318	PFAM AMP-dependent synthetase and ligase
HBK89_02505	COG1530	ribonuclease E activity
HBK89_02520	COG0546	phosphoglycolate phosphatase activity
HBK89_02525	COG2378	regulation of single-species biofilm formation
HBK89_02530	COG0625	glutathione transferase activity
HBK89_02540	COG0583	DNA-binding transcription factor activity
HBK89_02605	COG0473	3-isopropylmalate dehydrogenase activity
HBK89_02660	COG1301	dicarboxylic acid transport
HBK89_02670	COG1560	Kdo2-lipid A biosynthetic process
HBK89_02675	COG1280	lysine exporter protein (LysE YggA)
HBK89_02685	COG2900	Belongs to the SlyX family
HBK89_02695	COG1733	regulation of RNA biosynthetic process
HBK89_02720	COG0210	DNA helicase
HBK89_02725	COG0724	RNA recognition motif
HBK89_02745	COG4651	solute:proton antiporter activity
HBK89_02745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBK89_02770	COG0788	formyltetrahydrofolate deformylase activity
HBK89_02870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBK89_02870	COG2813	Specifically methylates the guanine in position
HBK89_02880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBK89_02900	COG0740	serine-type endopeptidase activity
HBK89_02920	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBK89_02920	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBK89_02925	COG0280	phosphate acetyltransferase
HBK89_02925	COG0857	belongs to the CobB CobQ family
HBK89_02930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBK89_02945	COG0800	Aldolase
HBK89_02955	COG3265	gluconokinase activity
HBK89_02960	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_02970	COG2267	carboxylic ester hydrolase activity
HBK89_02985	COG0793	Belongs to the peptidase S41A family
HBK89_03020	COG1426	Protein conserved in bacteria
HBK89_03065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBK89_03075	COG0318	PFAM AMP-dependent synthetase and ligase
HBK89_03090	COG2986	histidine ammonia-lyase
HBK89_03130	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_03135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBK89_03155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBK89_03165	COG1162	GTPase activity
HBK89_03170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HBK89_03185	COG1538	Outer membrane efflux protein
HBK89_03190	COG0577	efflux transmembrane transporter activity
HBK89_03190	COG1136	(ABC) transporter
HBK89_03195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_03220	COG0028	Belongs to the TPP enzyme family
HBK89_03225	COG0440	acetolactate synthase activity
HBK89_03260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBK89_03275	COG0084	hydrolase, TatD family'
HBK89_03290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBK89_03300	COG0583	DNA-binding transcription factor activity
HBK89_03310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBK89_03315	COG2814	Major facilitator Superfamily
HBK89_03325	COG0697	spore germination
HBK89_03355	COG3622	Belongs to the hyi family
HBK89_03360	COG2084	Dehydrogenase
HBK89_03365	COG1024	Enoyl-CoA hydratase
HBK89_03370	COG0784	Response regulator, receiver
HBK89_03370	COG5002	protein histidine kinase activity
HBK89_03370	COG2205	protein histidine kinase activity
HBK89_03390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBK89_03400	COG3956	TIGRFAM MazG family protein
HBK89_03405	COG1555	photosystem II stabilization
HBK89_03410	COG0617	tRNA 3'-terminal CCA addition
HBK89_03415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBK89_03435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBK89_03440	COG3028	Belongs to the UPF0307 family
HBK89_03445	COG0318	PFAM AMP-dependent synthetase and ligase
HBK89_03460	COG0625	glutathione transferase activity
HBK89_03465	COG1238	metal cluster binding
HBK89_03505	COG0072	phenylalanine-tRNA ligase activity
HBK89_03535	COG0248	Ppx GppA phosphatase
HBK89_03545	COG0037	tRNA processing
HBK89_03595	COG1764	response to oxidative stress
HBK89_03600	COG1846	Transcriptional regulator
HBK89_03610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBK89_03670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBK89_03675	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HBK89_03680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBK89_03690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBK89_03745	COG1214	PFAM Peptidase M22, glycoprotease
HBK89_03770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBK89_03775	COG0561	phosphatase activity
HBK89_03785	COG2132	Multicopper oxidase
HBK89_03790	COG3667	copper resistance
HBK89_03805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBK89_03810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBK89_03815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBK89_03845	COG1063	alcohol dehydrogenase
HBK89_03850	COG0583	DNA-binding transcription factor activity
HBK89_03855	COG1960	acyl-CoA dehydrogenase activity
HBK89_03860	COG2814	Major facilitator Superfamily
HBK89_03865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HBK89_03875	COG1053	succinate dehydrogenase
HBK89_03880	COG0583	DNA-binding transcription factor activity
HBK89_03895	COG0583	DNA-binding transcription factor activity
HBK89_03905	COG1473	amidohydrolase
HBK89_03925	COG0583	DNA-binding transcription factor activity
HBK89_03940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBK89_03960	COG0384	phenazine biosynthesis protein PhzF
HBK89_03980	COG4993	Dehydrogenase
HBK89_04050	COG2205	protein histidine kinase activity
HBK89_04060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBK89_04080	COG0745	RESPONSE REGULATOR receiver
HBK89_04085	COG2205	protein histidine kinase activity
HBK89_04120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HBK89_04150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBK89_04155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBK89_04175	COG0583	DNA-binding transcription factor activity
HBK89_04195	COG0668	transmembrane transport
HBK89_04205	COG2081	HI0933 family
HBK89_04210	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBK89_04240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBK89_04240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBK89_04250	COG0489	protein tyrosine kinase activity
HBK89_04300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBK89_04310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBK89_04325	COG0730	response to heat
HBK89_04335	COG1196	nuclear chromosome segregation
HBK89_04355	COG2223	nitrite transmembrane transporter activity
HBK89_04360	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HBK89_04365	COG1877	trehalose-phosphatase activity
HBK89_04370	COG0596	Alpha beta hydrolase
HBK89_04370	COG2226	methyltransferase
HBK89_04370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBK89_04385	COG4106	trans-aconitate 2-methyltransferase activity
HBK89_04400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBK89_04405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBK89_04410	COG0009	L-threonylcarbamoyladenylate synthase
HBK89_04415	COG3101	peptidyl-lysine hydroxylation
HBK89_04420	COG1399	metal-binding, possibly nucleic acid-binding protein
HBK89_04445	COG1652	LysM domain
HBK89_04450	COG0351	phosphomethylpyrimidine kinase
HBK89_04450	COG0352	thiamine-phosphate diphosphorylase activity
HBK89_04450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBK89_04460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBK89_04490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBK89_04520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HBK89_04535	COG0358	DNA primase activity
HBK89_04545	COG0564	pseudouridine synthase activity
HBK89_04570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBK89_04590	COG0583	DNA-binding transcription factor activity
HBK89_04595	COG0473	3-isopropylmalate dehydrogenase activity
HBK89_04615	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_04635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HBK89_04635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBK89_04695	COG0456	acetyltransferase
HBK89_04705	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HBK89_04710	COG0492	ferredoxin-NADP+ reductase activity
HBK89_04715	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBK89_04715	COG1674	ftsk spoiiie
HBK89_04720	COG1280	lysine exporter protein (LysE YggA)
HBK89_04745	COG2894	cell division
HBK89_04760	COG0204	Acyl-transferase
HBK89_04765	COG2885	chlorophyll binding
HBK89_04770	COG0210	DNA helicase
HBK89_04780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBK89_04795	COG0121	glutamine amidotransferase
HBK89_04815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBK89_04820	COG0735	belongs to the Fur family
HBK89_04845	COG0420	3'-5' exonuclease activity
HBK89_04865	COG1090	epimerase
HBK89_04880	COG2050	protein possibly involved in aromatic compounds catabolism
HBK89_04890	COG2814	Major facilitator Superfamily
HBK89_04895	COG0405	Gamma-glutamyltransferase
HBK89_04965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBK89_05055	COG1484	DNA-dependent DNA replication
HBK89_05250	COG2026	Addiction module toxin, RelE StbE family
HBK89_05290	COG0592	DNA-directed DNA polymerase activity
HBK89_05385	COG0582	viral genome integration into host DNA
HBK89_05440	COG0629	single-stranded DNA binding
HBK89_05475	COG0084	hydrolase, TatD family'
HBK89_05495	COG0477	Major facilitator Superfamily
HBK89_05500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBK89_05510	COG1595	DNA-templated transcription, initiation
HBK89_05565	COG0531	amino acid
HBK89_05570	COG2040	homocysteine
HBK89_05595	COG1309	transcriptional regulator
HBK89_05600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBK89_05605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBK89_05615	COG1607	acyl-coa hydrolase
HBK89_05625	COG0523	cobalamin synthesis protein
HBK89_05635	COG4681	YaeQ
HBK89_05645	COG0726	polysaccharide deacetylase
HBK89_05645	COG1649	PFAM Uncharacterised BCR, COG1649
HBK89_05650	COG1215	transferase activity, transferring glycosyl groups
HBK89_05660	COG1024	Enoyl-CoA hydratase
HBK89_05675	COG1414	Transcriptional regulator
HBK89_05695	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_05705	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBK89_05710	COG2271	Major facilitator Superfamily
HBK89_05720	COG2267	carboxylic ester hydrolase activity
HBK89_05725	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_05740	COG0028	Belongs to the TPP enzyme family
HBK89_05750	COG0477	Major facilitator Superfamily
HBK89_05755	COG0242	peptide deformylase activity
HBK89_05760	COG2066	Belongs to the glutaminase family
HBK89_05765	COG2207	Transcriptional regulator
HBK89_05770	COG2223	nitrite transmembrane transporter activity
HBK89_05785	COG0583	DNA-binding transcription factor activity
HBK89_05790	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_05795	COG2271	Major facilitator Superfamily
HBK89_05800	COG3959	Transketolase, thiamine diphosphate binding domain
HBK89_05805	COG3958	Transketolase
HBK89_05815	COG0306	phosphate transporter
HBK89_05835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBK89_05880	COG4181	ATPase activity
HBK89_05885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBK89_05910	COG0583	DNA-binding transcription factor activity
HBK89_05920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBK89_05925	COG1773	rubredoxin
HBK89_05980	COG2851	Citrate transporter
HBK89_05985	COG1253	flavin adenine dinucleotide binding
HBK89_06025	COG0804	urea catabolic process
HBK89_06035	COG0830	nickel cation binding
HBK89_06050	COG0742	ribosomal rna small subunit methyltransferase
HBK89_06055	COG0768	penicillin binding
HBK89_06080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBK89_06085	COG2878	Part of a membrane complex involved in electron transport
HBK89_06090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBK89_06100	COG3384	dioxygenase
HBK89_06125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBK89_06450	COG0739	heme binding
HBK89_06500	COG2194	sulfuric ester hydrolase activity
HBK89_06535	COG0006	proline dipeptidase activity
HBK89_06540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBK89_06545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBK89_06565	COG1279	arginine transmembrane transporter activity
HBK89_06570	COG0583	DNA-binding transcription factor activity
HBK89_06610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBK89_06615	COG1388	LysM domain
HBK89_06615	COG0741	lytic transglycosylase activity
HBK89_06615	COG0741	lytic transglycosylase activity
HBK89_06615	COG1388	LysM domain
HBK89_06625	COG4174	ABC transporter (Permease)
HBK89_06630	COG4239	(ABC) transporter, permease
HBK89_06635	COG4172	Belongs to the ABC transporter superfamily
HBK89_06655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBK89_06665	COG4251	negative regulation of phosphorylation
HBK89_06665	COG5001	Diguanylate cyclase
HBK89_06665	COG3706	GGDEF domain
HBK89_06665	COG2203	Gaf domain
HBK89_06675	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBK89_06675	COG1902	pentaerythritol trinitrate reductase activity
HBK89_06715	COG1309	transcriptional regulator
HBK89_06720	COG1741	Belongs to the pirin family
HBK89_06735	COG2072	flavoprotein involved in K transport
HBK89_06745	COG2252	PERMEase
HBK89_06750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HBK89_06755	COG3038	cytochrome b561
HBK89_06765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBK89_06775	COG0527	aspartate kinase activity
HBK89_06785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBK89_06795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBK89_06810	COG0667	Aldo Keto reductase
HBK89_06825	COG1765	OsmC-like protein
HBK89_06840	COG0542	response to heat
HBK89_06875	COG2885	chlorophyll binding
HBK89_06885	COG0625	glutathione transferase activity
HBK89_06890	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HBK89_06910	COG3634	alkyl hydroperoxide reductase activity
HBK89_06920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HBK89_06930	COG0450	alkyl hydroperoxide reductase
HBK89_06935	COG1643	Atp-dependent helicase
HBK89_06950	COG2814	Major facilitator Superfamily
HBK89_06955	COG3135	benzoate transporter
HBK89_06960	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_06965	COG0633	Ferredoxin
HBK89_06965	COG0543	2 iron, 2 sulfur cluster binding
HBK89_06970	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBK89_06975	COG4638	Rieske (2fe-2S)
HBK89_06980	COG0583	DNA-binding transcription factor activity
HBK89_07030	COG1570	exodeoxyribonuclease VII activity
HBK89_07065	COG1280	lysine exporter protein (LysE YggA)
HBK89_07070	COG1278	Cold shock
HBK89_07105	COG2814	Major facilitator Superfamily
HBK89_07145	COG0517	IMP dehydrogenase activity
HBK89_07145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HBK89_07150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBK89_07160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBK89_07165	COG1137	ATPase activity
HBK89_07175	COG1538	Outer membrane efflux protein
HBK89_07205	COG4122	O-methyltransferase activity
HBK89_07215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HBK89_07230	COG1522	sequence-specific DNA binding
HBK89_07235	COG5006	permease, DMT superfamily
HBK89_07245	COG1560	Kdo2-lipid A biosynthetic process
HBK89_07255	COG2814	Major facilitator Superfamily
HBK89_07275	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBK89_07305	COG3501	Rhs element vgr protein
HBK89_07310	COG3209	COG3209 Rhs family protein
HBK89_07325	COG0583	DNA-binding transcription factor activity
HBK89_07330	COG1914	H( )-stimulated, divalent metal cation uptake system
HBK89_07350	COG4770	biotin carboxylase activity
HBK89_07355	COG0038	chloride channel
HBK89_07375	COG1309	transcriptional regulator
HBK89_07385	COG1063	alcohol dehydrogenase
HBK89_07400	COG0439	Biotin carboxylase
HBK89_07405	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBK89_07425	COG0864	Transcriptional regulator
HBK89_07435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBK89_07440	COG1116	anion transmembrane transporter activity
HBK89_07565	COG0590	tRNA wobble adenosine to inosine editing
HBK89_07570	COG2807	transmembrane transport
HBK89_07585	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBK89_07600	COG0789	Transcriptional regulator
HBK89_07610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBK89_07630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBK89_07640	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBK89_07655	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_07660	COG0531	amino acid
HBK89_07665	COG1760	l-serine dehydratase
HBK89_07670	COG2030	dehydratase
HBK89_07670	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_07675	COG3396	Phenylacetate-CoA oxygenase
HBK89_07680	COG3460	Phenylacetate-CoA oxygenase
HBK89_07685	COG3396	Phenylacetate-CoA oxygenase
HBK89_07690	COG2151	metal-sulfur cluster biosynthetic enzyme
HBK89_07695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBK89_07700	COG1024	Enoyl-CoA hydratase
HBK89_07705	COG1024	Enoyl-CoA hydratase
HBK89_07710	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBK89_07715	COG0183	Belongs to the thiolase family
HBK89_07720	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBK89_07725	COG3327	negative regulation of DNA-templated transcription, initiation
HBK89_07735	COG2050	protein possibly involved in aromatic compounds catabolism
HBK89_07770	COG0753	catalase activity
HBK89_07775	COG3038	cytochrome b561
HBK89_07795	COG2267	carboxylic ester hydrolase activity
HBK89_07800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBK89_07805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBK89_07810	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_07820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBK89_07830	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_07835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBK89_07840	COG0583	DNA-binding transcription factor activity
HBK89_07850	COG1414	Transcriptional regulator
HBK89_07855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBK89_07865	COG1840	ABC-type Fe3 transport system, periplasmic component
HBK89_07870	COG3842	ATPase activity
HBK89_07885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBK89_07890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBK89_07895	COG2814	Major facilitator Superfamily
HBK89_07900	COG1960	acyl-CoA dehydrogenase activity
HBK89_07915	COG1024	Enoyl-CoA hydratase
HBK89_07925	COG2814	Major facilitator Superfamily
HBK89_07935	COG0183	Belongs to the thiolase family
HBK89_07940	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBK89_07945	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_07950	COG1024	Enoyl-CoA hydratase
HBK89_07955	COG1960	acyl-CoA dehydrogenase activity
HBK89_07960	COG2814	Major facilitator Superfamily
HBK89_07965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBK89_07970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBK89_07980	COG2814	Major facilitator Superfamily
HBK89_07990	COG1960	acyl-CoA dehydrogenase activity
HBK89_08005	COG0583	DNA-binding transcription factor activity
HBK89_08015	COG4770	biotin carboxylase activity
HBK89_08020	COG1024	Enoyl-CoA hydratase
HBK89_08025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBK89_08030	COG1960	acyl-CoA dehydrogenase activity
HBK89_08035	COG1309	transcriptional regulator
HBK89_08040	COG0318	PFAM AMP-dependent synthetase and ligase
HBK89_08060	COG0583	DNA-binding transcription factor activity
HBK89_08110	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_08130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBK89_08150	COG2205	protein histidine kinase activity
HBK89_08150	COG0784	Response regulator, receiver
HBK89_08170	COG0765	amino acid transport
HBK89_08175	COG0765	amino acid transport
HBK89_08180	COG1126	abc transporter atp-binding protein
HBK89_08185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBK89_08190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBK89_08205	COG1280	lysine exporter protein (LysE YggA)
HBK89_08215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBK89_08220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBK89_08225	COG1045	serine acetyltransferase
HBK89_08240	COG0583	DNA-binding transcription factor activity
HBK89_08245	COG0625	glutathione transferase activity
HBK89_08250	COG0625	glutathione transferase activity
HBK89_08255	COG0583	DNA-binding transcription factor activity
HBK89_08265	COG1346	cytolysis
HBK89_08285	COG2814	Major facilitator Superfamily
HBK89_08295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HBK89_08300	COG3052	prosthetic group binding
HBK89_08320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBK89_08340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBK89_08350	COG1294	oxidase, subunit
HBK89_08355	COG1271	oxidase subunit
HBK89_08375	COG0477	Major facilitator Superfamily
HBK89_08385	COG4521	taurine ABC transporter
HBK89_08390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBK89_08395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBK89_08400	COG2175	clavaminate synthase activity
HBK89_08410	COG1953	Uracil, thiamine, allantoin
HBK89_08420	COG0583	DNA-binding transcription factor activity
HBK89_08430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBK89_08445	COG0640	Transcriptional regulator
HBK89_08450	COG0798	PFAM Bile acid sodium symporter
HBK89_08455	COG0583	DNA-binding transcription factor activity
HBK89_08470	COG3634	alkyl hydroperoxide reductase activity
HBK89_08510	COG0436	Aminotransferase
HBK89_08520	COG0386	Belongs to the glutathione peroxidase family
HBK89_08560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBK89_08585	COG0012	GTP binding
HBK89_08590	COG2011	ABC-type metal ion transport system permease component
HBK89_08595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBK89_08605	COG1464	Belongs to the NlpA lipoprotein family
HBK89_08635	COG0765	amino acid transport
HBK89_08640	COG0765	amino acid transport
HBK89_08645	COG1126	abc transporter atp-binding protein
HBK89_08655	COG1522	sequence-specific DNA binding
HBK89_08670	COG1309	transcriptional regulator
HBK89_08690	COG0583	DNA-binding transcription factor activity
HBK89_08700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBK89_08710	COG0697	spore germination
HBK89_08735	COG3121	Chaperone
HBK89_08740	COG3539	Fimbrial protein
HBK89_08765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBK89_08765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBK89_08810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBK89_08820	COG2353	YceI-like domain
HBK89_08830	COG3698	Phosphodiester glycosidase
HBK89_08845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBK89_08850	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBK89_08850	COG0506	proline dehydrogenase activity
HBK89_08850	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBK89_08860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBK89_08865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBK89_08885	COG1132	(ABC) transporter
HBK89_08890	COG3122	Protein conserved in bacteria
HBK89_08895	COG3619	membrane
HBK89_08910	COG0640	Transcriptional regulator
HBK89_08920	COG2850	peptidyl-arginine hydroxylation
HBK89_08925	COG0424	maF-like protein
HBK89_08945	COG0191	fructose-bisphosphate aldolase activity
HBK89_08950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBK89_08965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBK89_08975	COG1192	Involved in chromosome partitioning
HBK89_08980	COG1475	DNA binding
HBK89_08985	COG0811	peptide transport
HBK89_08995	COG1132	(ABC) transporter
HBK89_09000	COG1663	tetraacyldisaccharide 4'-kinase activity
HBK89_09020	COG0084	hydrolase, TatD family'
HBK89_09085	COG0776	regulation of translation
HBK89_09115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBK89_09120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBK89_09170	COG0339	signal peptide processing
HBK89_09180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBK89_09215	COG0702	epimerase
HBK89_09220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBK89_09240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBK89_09270	COG0316	Belongs to the HesB IscA family
HBK89_09275	COG0822	iron-sulfur transferase activity
HBK89_09300	COG0776	regulation of translation
HBK89_09305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBK89_09310	COG2207	Transcriptional regulator
HBK89_09315	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBK89_09320	COG1960	acyl-CoA dehydrogenase activity
HBK89_09325	COG1960	acyl-CoA dehydrogenase activity
HBK89_09340	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBK89_09360	COG4264	IucA IucC family
HBK89_09365	COG4264	IucA IucC family
HBK89_09420	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HBK89_09440	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBK89_09445	COG0730	response to heat
HBK89_09465	COG4773	Receptor
HBK89_09470	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBK89_09485	COG1131	(ABC) transporter
HBK89_09490	COG0842	Transport permease protein
HBK89_09495	COG0842	Transport permease protein
HBK89_09550	COG2226	methyltransferase
HBK89_09565	COG0133	tryptophan synthase activity
HBK89_09580	COG3706	GGDEF domain
HBK89_09595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBK89_09600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBK89_09605	COG0022	dehydrogenase e1 component
HBK89_09610	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBK89_09615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBK89_09625	COG1063	alcohol dehydrogenase
HBK89_09630	COG3781	membrane
HBK89_09640	COG3453	Protein conserved in bacteria
HBK89_09640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBK89_09650	COG0730	response to heat
HBK89_09665	COG2207	Transcriptional regulator
HBK89_09665	COG3708	Transcriptional regulator
HBK89_09670	COG1733	regulation of RNA biosynthetic process
HBK89_09675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBK89_09685	COG2188	Transcriptional regulator
HBK89_09700	COG4521	taurine ABC transporter
HBK89_09705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBK89_09725	COG0477	Major facilitator Superfamily
HBK89_09735	COG1027	Aspartate ammonia-lyase
HBK89_09750	COG0583	DNA-binding transcription factor activity
HBK89_09755	COG0583	DNA-binding transcription factor activity
HBK89_09760	COG0183	Belongs to the thiolase family
HBK89_09765	COG2031	fatty acid transporter
HBK89_09770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBK89_09780	COG0583	DNA-binding transcription factor activity
HBK89_09790	COG2610	gluconate transmembrane transporter activity
HBK89_09795	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_09805	COG2207	Transcriptional regulator
HBK89_09820	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_09845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBK89_09845	COG0543	2 iron, 2 sulfur cluster binding
HBK89_09850	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBK89_09855	COG4638	Rieske (2fe-2S)
HBK89_09865	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBK89_09870	COG4149	molybdate abc transporter
HBK89_09875	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBK89_09880	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_09885	COG1535	isochorismatase
HBK89_09885	COG3433	isochorismatase activity
HBK89_09950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBK89_09965	COG0753	catalase activity
HBK89_09975	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HBK89_10005	COG3539	Fimbrial protein
HBK89_10025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBK89_10045	COG2072	flavoprotein involved in K transport
HBK89_10055	COG1538	Outer membrane efflux protein
HBK89_10060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBK89_10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_10070	COG0745	RESPONSE REGULATOR receiver
HBK89_10075	COG2205	protein histidine kinase activity
HBK89_10085	COG2207	Transcriptional regulator
HBK89_10100	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_10150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HBK89_10270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBK89_10290	COG1120	ATPase activity
HBK89_10305	COG1064	alcohol dehydrogenase
HBK89_10320	COG2207	Transcriptional regulator
HBK89_10325	COG2084	Dehydrogenase
HBK89_10335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBK89_10340	COG0583	DNA-binding transcription factor activity
HBK89_10350	COG0129	dihydroxy-acid dehydratase activity
HBK89_10355	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_10370	COG1566	PFAM secretion protein HlyD family protein
HBK89_10390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBK89_10420	COG0583	DNA-binding transcription factor activity
HBK89_10435	COG2188	Transcriptional regulator
HBK89_10465	COG3210	domain, Protein
HBK89_10470	COG2831	hemolysin activation secretion protein
HBK89_10480	COG1473	amidohydrolase
HBK89_10490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBK89_10490	COG0475	glutathione-regulated potassium exporter activity
HBK89_10500	COG0583	DNA-binding transcription factor activity
HBK89_10505	COG1335	isochorismatase
HBK89_10515	COG1309	transcriptional regulator
HBK89_10545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBK89_10555	COG1902	pentaerythritol trinitrate reductase activity
HBK89_10555	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBK89_10560	COG1846	Transcriptional regulator
HBK89_10580	COG0753	catalase activity
HBK89_10595	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_10610	COG3162	membrane
HBK89_10620	COG3829	transcription factor binding
HBK89_10625	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_10630	COG1960	acyl-CoA dehydrogenase activity
HBK89_10650	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_10670	COG2186	Transcriptional regulator
HBK89_10680	COG0583	DNA-binding transcription factor activity
HBK89_10685	COG4948	Mandelate Racemase Muconate Lactonizing
HBK89_10690	COG4829	muconolactone delta-isomerase
HBK89_10700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBK89_10705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBK89_10710	COG0183	Belongs to the thiolase family
HBK89_10715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBK89_10725	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_10755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBK89_10765	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_10775	COG4638	Rieske (2fe-2S)
HBK89_10795	COG0154	amidase activity
HBK89_10805	COG2814	Major facilitator Superfamily
HBK89_10830	COG1960	acyl-CoA dehydrogenase activity
HBK89_10835	COG0583	DNA-binding transcription factor activity
HBK89_10840	COG1414	Transcriptional regulator
HBK89_10855	COG2391	methyltransferase activity
HBK89_10865	COG4993	Dehydrogenase
HBK89_10870	COG3659	wide pore channel activity
HBK89_10875	COG3420	alginic acid biosynthetic process
HBK89_10880	COG0710	3-dehydroquinate dehydratase activity
HBK89_10885	COG3485	protocatechuate 3,4-dioxygenase
HBK89_10890	COG3485	protocatechuate 3,4-dioxygenase
HBK89_10895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBK89_10900	COG2271	Major facilitator Superfamily
HBK89_10905	COG0596	Alpha beta hydrolase
HBK89_10910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBK89_10915	COG0183	Belongs to the thiolase family
HBK89_10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBK89_10925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBK89_10935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HBK89_10940	COG2323	membrane
HBK89_10985	COG1902	pentaerythritol trinitrate reductase activity
HBK89_10985	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBK89_11010	COG0542	response to heat
HBK89_11015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HBK89_11045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBK89_11050	COG0569	domain protein
HBK89_11055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBK89_11070	COG4774	siderophore transport
HBK89_11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBK89_11085	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBK89_11105	COG1294	oxidase, subunit
HBK89_11110	COG4890	Cyd operon protein YbgT
HBK89_11125	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HBK89_11135	COG0552	protein localization to endoplasmic reticulum
HBK89_11160	COG0517	IMP dehydrogenase activity
HBK89_11160	COG0516	GMP reductase activity
HBK89_11165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBK89_11170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBK89_11180	COG0583	DNA-binding transcription factor activity
HBK89_11185	COG0024	Methionine aminopeptidase
HBK89_11215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBK89_11215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBK89_11220	COG1105	Belongs to the carbohydrate kinase PfkB family
HBK89_11225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBK89_11225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBK89_11225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBK89_11245	COG3300	MHYT domain
HBK89_11245	COG5001	Diguanylate cyclase
HBK89_11260	COG2135	peptidase activity
HBK89_11265	COG0659	secondary active sulfate transmembrane transporter activity
HBK89_11285	COG1113	amino acid transport
HBK89_11295	COG1522	sequence-specific DNA binding
HBK89_11320	COG1011	Hydrolase
HBK89_11325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBK89_11335	COG2137	regulation of response to DNA damage stimulus
HBK89_11350	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBK89_11385	COG0575	Belongs to the CDS family
HBK89_11390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBK89_11410	COG3852	Histidine kinase
HBK89_11415	COG2204	response regulator
HBK89_11470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBK89_11475	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBK89_11495	COG0697	spore germination
HBK89_11500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBK89_11510	COG0303	'Molybdopterin
HBK89_11515	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBK89_11515	COG0315	cyclic pyranopterin monophosphate synthase activity
HBK89_11530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBK89_11535	COG0243	molybdopterin cofactor binding
HBK89_11545	COG0243	molybdopterin cofactor binding
HBK89_11550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBK89_11555	COG2146	nitrite reductase [NAD(P)H] activity
HBK89_11555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBK89_11565	COG0745	RESPONSE REGULATOR receiver
HBK89_11570	COG1116	anion transmembrane transporter activity
HBK89_11570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBK89_11590	COG0511	ligase activity, forming carbon-carbon bonds
HBK89_11605	COG2814	Major facilitator Superfamily
HBK89_11625	COG0069	glutamate synthase activity
HBK89_11645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBK89_11655	COG1454	alcohol dehydrogenase
HBK89_11660	COG0824	Thioesterase
HBK89_11675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBK89_11695	COG2030	dehydratase
HBK89_11705	COG0183	Belongs to the thiolase family
HBK89_11715	COG0583	DNA-binding transcription factor activity
HBK89_11720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBK89_11730	COG1522	sequence-specific DNA binding
HBK89_11735	COG3135	benzoate transporter
HBK89_11745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBK89_11770	COG0589	response to stress
HBK89_11775	COG0488	(ABC) transporter
HBK89_11795	COG4773	Receptor
HBK89_11830	COG0668	transmembrane transport
HBK89_11840	COG1309	transcriptional regulator
HBK89_11855	COG1605	Chorismate mutase
HBK89_11885	COG0308	aminopeptidase N
HBK89_11905	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBK89_11915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBK89_11920	COG1454	alcohol dehydrogenase
HBK89_11940	COG0531	amino acid
HBK89_11945	COG4303	Ethanolamine ammonia lyase large subunit
HBK89_11950	COG4302	ethanolamine ammonia-lyase activity
HBK89_11955	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBK89_11955	COG0519	Catalyzes the synthesis of GMP from XMP
HBK89_11960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBK89_11970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBK89_11985	COG0697	spore germination
HBK89_11990	COG1923	regulation of RNA biosynthetic process
HBK89_12000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBK89_12005	COG0802	atpase or kinase
HBK89_12025	COG1187	pseudouridine synthase activity
HBK89_12040	COG0583	DNA-binding transcription factor activity
HBK89_12055	COG2814	Major facilitator Superfamily
HBK89_12060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBK89_12085	COG0729	surface antigen
HBK89_12105	COG0174	glutamine synthetase
HBK89_12110	COG0745	RESPONSE REGULATOR receiver
HBK89_12115	COG2205	protein histidine kinase activity
HBK89_12125	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HBK89_12130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HBK89_12155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBK89_12160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBK89_12165	COG1960	acyl-CoA dehydrogenase activity
HBK89_12180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBK89_12205	COG0583	DNA-binding transcription factor activity
HBK89_12220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBK89_12230	COG3658	cytochrome
HBK89_12235	COG1215	transferase activity, transferring glycosyl groups
HBK89_12240	COG1649	PFAM Uncharacterised BCR, COG1649
HBK89_12240	COG0726	polysaccharide deacetylase
HBK89_12265	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBK89_12270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBK89_12280	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBK89_12305	COG0305	Participates in initiation and elongation during chromosome replication
HBK89_12310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBK89_12320	COG1305	Transglutaminase-like
HBK89_12330	COG2308	Evidence 4 Homologs of previously reported genes of
HBK89_12360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HBK89_12365	COG0138	bifunctional purine biosynthesis protein purh
HBK89_12370	COG0151	Belongs to the GarS family
HBK89_12375	COG1464	Belongs to the NlpA lipoprotein family
HBK89_12380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBK89_12385	COG2011	ABC-type metal ion transport system permease component
HBK89_12390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBK89_12405	COG1301	dicarboxylic acid transport
HBK89_12445	COG2433	Pfam Transposase IS66
HBK89_12455	COG3173	Aminoglycoside phosphotransferase
HBK89_12475	COG0482	sulfurtransferase activity
HBK89_12495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBK89_12495	COG3008	intermembrane lipid transfer
HBK89_12500	COG2995	paraquat-inducible protein a
HBK89_12510	COG2985	domain, Protein
HBK89_12535	COG0477	Major facilitator Superfamily
HBK89_12585	COG2186	Transcriptional regulator
HBK89_12595	COG0786	glutamate:sodium symporter activity
HBK89_12600	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBK89_12625	COG3111	PFAM Bacterial OB fold (BOF) protein
HBK89_12725	COG1610	YqeY-like protein
HBK89_12730	COG4783	chaperone-mediated protein folding
HBK89_12755	COG1286	toxin biosynthetic process
HBK89_12785	COG0778	Nitroreductase
HBK89_12795	COG0513	Belongs to the DEAD box helicase family
HBK89_12815	COG2363	Small membrane protein
HBK89_12845	COG1234	tRNA 3'-trailer cleavage
HBK89_12850	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBK89_12860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HBK89_12870	COG2819	hydrolase of the alpha beta superfamily
HBK89_12875	COG1960	acyl-CoA dehydrogenase activity
HBK89_12880	COG1301	dicarboxylic acid transport
HBK89_12885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBK89_12890	COG3139	Protein of unknown function (DUF1315)
HBK89_12895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBK89_12900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBK89_12910	COG0494	nUDIX hydrolase
HBK89_12920	COG0642	Histidine kinase
HBK89_12925	COG0745	RESPONSE REGULATOR receiver
HBK89_12945	COG1720	tRNA m6t6A37 methyltransferase activity
HBK89_12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBK89_12970	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBK89_12980	COG4598	ABC transporter
HBK89_12985	COG4160	amino acid transport
HBK89_12990	COG4215	(ABC) transporter
HBK89_13005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_13050	COG1131	(ABC) transporter
HBK89_13055	COG0842	Transport permease protein
HBK89_13070	COG0772	Belongs to the SEDS family
HBK89_13075	COG2951	lytic endotransglycosylase activity
HBK89_13100	COG2207	Transcriptional regulator
HBK89_13115	COG0052	Belongs to the universal ribosomal protein uS2 family
HBK89_13120	COG0024	Methionine aminopeptidase
HBK89_13130	COG2223	nitrite transmembrane transporter activity
HBK89_13140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBK89_13145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBK89_13150	COG1960	acyl-CoA dehydrogenase activity
HBK89_13165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBK89_13170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBK89_13175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBK89_13195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBK89_13200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBK89_13205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBK89_13240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBK89_13250	COG0174	glutamine synthetase
HBK89_13255	COG3104	oligopeptide transport
HBK89_13265	COG0512	Glutamine amidotransferase of anthranilate synthase
HBK89_13270	COG0308	aminopeptidase N
HBK89_13300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HBK89_13345	COG3739	integral membrane protein
HBK89_13360	COG1169	isochorismate synthase
HBK89_13370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBK89_13380	COG1132	(ABC) transporter
HBK89_13395	COG1535	isochorismatase
HBK89_13395	COG3433	isochorismatase activity
HBK89_13400	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBK89_13405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBK89_13415	COG4774	siderophore transport
HBK89_13420	COG4607	ABC-type enterochelin transport system periplasmic component
HBK89_13425	COG4604	ABC transporter, ATP-binding protein
HBK89_13430	COG4605	iron ion homeostasis
HBK89_13435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBK89_13440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBK89_13455	COG2964	Protein conserved in bacteria
HBK89_13465	COG1741	Belongs to the pirin family
HBK89_13485	COG1309	transcriptional regulator
HBK89_13495	COG4948	Mandelate Racemase Muconate Lactonizing
HBK89_13500	COG2814	Major facilitator Superfamily
HBK89_13545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBK89_13545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HBK89_13550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBK89_13555	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_13565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBK89_13570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBK89_13575	COG0583	DNA-binding transcription factor activity
HBK89_13580	COG1113	amino acid transport
HBK89_13600	COG2508	Transcriptional regulator
HBK89_13600	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBK89_13635	COG2879	small protein
HBK89_13640	COG1966	Carbon starvation protein
HBK89_13685	COG1067	ATP-dependent peptidase activity
HBK89_13690	COG0583	DNA-binding transcription factor activity
HBK89_13715	COG1686	Belongs to the peptidase S11 family
HBK89_13720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBK89_13750	COG3328	transposase activity
HBK89_13760	COG0616	signal peptide processing
HBK89_13765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBK89_13775	COG0573	inorganic phosphate transmembrane transporter activity
HBK89_13780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBK89_13785	COG1113	amino acid transport
HBK89_13790	COG3961	Belongs to the TPP enzyme family
HBK89_13795	COG1522	sequence-specific DNA binding
HBK89_13805	COG0076	glutamate decarboxylase activity
HBK89_13810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBK89_13820	COG1309	transcriptional regulator
HBK89_13835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBK89_13870	COG0352	thiamine-phosphate diphosphorylase activity
HBK89_13895	COG0612	Peptidase, M16
HBK89_13910	COG0583	DNA-binding transcription factor activity
HBK89_13915	COG0477	Major facilitator Superfamily
HBK89_13940	COG1187	pseudouridine synthase activity
HBK89_13955	COG1686	Belongs to the peptidase S11 family
HBK89_13960	COG1252	NADH dehydrogenase
HBK89_13970	COG0415	Belongs to the DNA photolyase family
HBK89_13985	COG1215	transferase activity, transferring glycosyl groups
HBK89_14015	COG2070	2-Nitropropane dioxygenase
HBK89_14070	COG0556	nucleotide-excision repair
HBK89_14090	COG0436	Aminotransferase
HBK89_14120	COG4221	oxidoreductase activity
HBK89_14130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBK89_14135	COG1381	Involved in DNA repair and RecF pathway recombination
HBK89_14145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBK89_14160	COG0681	Belongs to the peptidase S26 family
HBK89_14175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBK89_14195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBK89_14200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBK89_14205	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBK89_14215	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBK89_14220	COG4208	sulfate ABC transporter
HBK89_14225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBK89_14230	COG0583	DNA-binding transcription factor activity
HBK89_14235	COG4625	pathogenesis
HBK89_14250	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBK89_14265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBK89_14275	COG1056	cytidyltransferase-related domain
HBK89_14275	COG1051	belongs to the nudix hydrolase family
HBK89_14280	COG1024	Enoyl-CoA hydratase
HBK89_14290	COG2814	Major facilitator Superfamily
HBK89_14295	COG0047	phosphoribosylformylglycinamidine synthase activity
HBK89_14295	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBK89_14315	COG1473	amidohydrolase
HBK89_14320	COG0824	Thioesterase
HBK89_14340	COG0823	Involved in the tonB-independent uptake of proteins
HBK89_14360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBK89_14395	COG0628	permease
HBK89_14405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBK89_14410	COG0596	Alpha beta hydrolase
HBK89_14415	COG0616	signal peptide processing
HBK89_14415	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HBK89_14425	COG0658	competence protein
HBK89_14425	COG2333	competence protein COMEC
HBK89_14430	COG1136	(ABC) transporter
HBK89_14435	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBK89_14470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_14490	COG0463	Glycosyl transferase, family 2
HBK89_14520	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBK89_14525	COG1280	lysine exporter protein (LysE YggA)
HBK89_14535	COG0019	diaminopimelate decarboxylase activity
HBK89_14545	COG1113	amino acid transport
HBK89_14560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HBK89_14570	COG3339	Conserved Protein
HBK89_14575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBK89_14580	COG0243	molybdopterin cofactor binding
HBK89_14585	COG1929	Belongs to the glycerate kinase type-1 family
HBK89_14600	COG0778	Nitroreductase
HBK89_14625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBK89_14640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBK89_14660	COG0741	lytic transglycosylase activity
HBK89_14680	COG0584	glycerophosphoryl diester phosphodiesterase
HBK89_14710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBK89_14715	COG1597	lipid kinase activity
HBK89_14730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBK89_14735	COG0477	Major facilitator Superfamily
HBK89_14785	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBK89_14790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBK89_14815	COG0505	Belongs to the CarA family
HBK89_14835	COG0589	response to stress
HBK89_14850	COG2843	Capsule synthesis protein
HBK89_14890	COG2321	neutral zinc metallopeptidase
HBK89_14895	COG2354	Protein conserved in bacteria
HBK89_14915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBK89_14940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBK89_14945	COG1053	succinate dehydrogenase
HBK89_14950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBK89_14955	COG2009	succinate dehydrogenase
HBK89_14995	COG2921	Belongs to the UPF0250 family
HBK89_15000	COG0321	lipoyl(octanoyl) transferase activity
HBK89_15015	COG0531	amino acid
HBK89_15025	COG1733	regulation of RNA biosynthetic process
HBK89_15030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBK89_15035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBK89_15035	COG1648	precorrin-2 dehydrogenase activity
HBK89_15050	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBK89_15080	COG0671	phosphoesterase, PA-phosphatase related
HBK89_15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_15095	COG1538	Outer membrane efflux protein
HBK89_15100	COG0393	Putative heavy-metal-binding
HBK89_15105	COG0393	Putative heavy-metal-binding
HBK89_15115	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_15125	COG0525	valine-tRNA ligase activity
HBK89_15145	COG0583	DNA-binding transcription factor activity
HBK89_15150	COG0004	ammonium transporteR
HBK89_15160	COG0642	Histidine kinase
HBK89_15165	COG0745	RESPONSE REGULATOR receiver
HBK89_15170	COG2194	sulfuric ester hydrolase activity
HBK89_15190	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBK89_15205	COG2315	Protein conserved in bacteria
HBK89_15210	COG0142	geranyltranstransferase activity
HBK89_15215	COG2828	Protein conserved in bacteria
HBK89_15220	COG1113	amino acid transport
HBK89_15240	COG2207	Transcriptional regulator
HBK89_15265	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBK89_15275	COG0560	Phosphoserine phosphatase
HBK89_15285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBK89_15295	COG1530	ribonuclease E activity
HBK89_15300	COG0424	maF-like protein
HBK89_15305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBK89_15310	COG1792	Involved in formation and maintenance of cell shape
HBK89_15315	COG1077	Cell shape determining protein MreB Mrl
HBK89_15320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBK89_15330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBK89_15370	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBK89_15375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBK89_15380	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBK89_15385	COG1115	amino acid carrier protein
HBK89_15405	COG2814	Major facilitator Superfamily
HBK89_15410	COG1289	transmembrane transporter activity
HBK89_15420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBK89_15460	COG1376	ErfK ybiS ycfS ynhG family protein
HBK89_15465	COG2832	Protein of unknown function (DUF454)
HBK89_15475	COG5510	response to toxic substance
HBK89_15495	COG0840	transmembrane signaling receptor activity
HBK89_15535	COG3422	double-strand break repair
HBK89_15540	COG2824	Alkylphosphonate utilization operon protein PhnA
HBK89_15545	COG3189	MarR family transcriptional regulator
HBK89_15555	COG0354	folic acid binding
HBK89_15560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBK89_15575	COG1902	pentaerythritol trinitrate reductase activity
HBK89_15590	COG4772	TonB-dependent receptor
HBK89_15595	COG2094	Belongs to the DNA glycosylase MPG family
HBK89_15625	COG2233	PERMEase
HBK89_15635	COG0833	amino acid
HBK89_15640	COG1690	Belongs to the RtcB family
HBK89_15650	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBK89_15650	COG2885	chlorophyll binding
HBK89_15660	COG0183	Belongs to the thiolase family
HBK89_15680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBK89_15700	COG2207	Transcriptional regulator
HBK89_15705	COG0183	Belongs to the thiolase family
HBK89_15740	COG1272	protein, Hemolysin III
HBK89_15745	COG0477	Major facilitator Superfamily
HBK89_15760	COG0450	alkyl hydroperoxide reductase
HBK89_15780	COG0285	dihydrofolate synthase activity
HBK89_15830	COG2096	Adenosyltransferase
HBK89_15850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HBK89_15855	COG0745	RESPONSE REGULATOR receiver
HBK89_15860	COG2205	protein histidine kinase activity
HBK89_15870	COG1960	acyl-CoA dehydrogenase activity
HBK89_15875	COG1960	acyl-CoA dehydrogenase activity
HBK89_15880	COG0583	DNA-binding transcription factor activity
HBK89_15885	COG0625	glutathione transferase activity
HBK89_15950	COG0438	transferase activity, transferring glycosyl groups
HBK89_15955	COG0463	Glycosyl transferase, family 2
HBK89_15960	COG0726	polysaccharide deacetylase
HBK89_15980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HBK89_15985	COG2205	protein histidine kinase activity
HBK89_16015	COG1862	Preprotein translocase
HBK89_16025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBK89_16030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBK89_16040	COG3781	membrane
HBK89_16045	COG0613	PHP domain protein
HBK89_16055	COG2350	Protein conserved in bacteria
HBK89_16085	COG1607	acyl-coa hydrolase
HBK89_16145	COG2199	diguanylate cyclase activity
HBK89_16155	COG1408	metallophosphoesterase
HBK89_16160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBK89_16170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBK89_16190	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBK89_16195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HBK89_16210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HBK89_16220	COG2969	positive regulation of protein catabolic process
HBK89_16240	COG1960	acyl-CoA dehydrogenase activity
HBK89_16245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBK89_16260	COG1309	transcriptional regulator
HBK89_16265	COG1960	acyl-CoA dehydrogenase activity
HBK89_16310	COG1183	phosphatidylcholine synthase activity
HBK89_16315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBK89_16345	COG1196	nuclear chromosome segregation
HBK89_16345	COG0739	heme binding
HBK89_16345	COG0741	lytic transglycosylase activity
HBK89_16355	COG1702	phosphate starvation-inducible protein PhoH
HBK89_16390	COG1295	ribonuclease BN
HBK89_16395	COG0697	spore germination
HBK89_16400	COG2169	Transcriptional regulator
HBK89_16405	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBK89_16450	COG0557	exoribonuclease II activity
HBK89_16455	COG0339	signal peptide processing
HBK89_16460	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBK89_16490	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBK89_16495	COG1960	acyl-CoA dehydrogenase activity
HBK89_16650	COG0626	cystathionine gamma-synthase activity
HBK89_16655	COG0433	COG0433 Predicted ATPase
HBK89_16660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBK89_16660	COG1017	nitric oxide dioxygenase activity
HBK89_16665	COG1959	2 iron, 2 sulfur cluster binding
HBK89_16680	COG1301	dicarboxylic acid transport
HBK89_16685	COG1946	Acyl-CoA thioesterase
HBK89_16705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBK89_16710	COG1040	competence protein
HBK89_16715	COG0494	nUDIX hydrolase
HBK89_16725	COG0598	Magnesium transport protein CorA
HBK89_16735	COG2854	intermembrane phospholipid transfer
HBK89_16745	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBK89_16750	COG1127	ABC transporter
HBK89_16760	COG0513	Belongs to the DEAD box helicase family
HBK89_16780	COG0408	coproporphyrinogen oxidase activity
HBK89_16795	COG1960	acyl-CoA dehydrogenase activity
HBK89_16805	COG1983	PspC domain protein
HBK89_16810	COG0517	IMP dehydrogenase activity
HBK89_16855	COG0583	DNA-binding transcription factor activity
HBK89_16895	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_16905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBK89_16910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBK89_16915	COG0833	amino acid
HBK89_16945	COG1192	Involved in chromosome partitioning
HBK89_16950	COG0628	permease
HBK89_16960	COG1289	transmembrane transporter activity
HBK89_16975	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBK89_16980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBK89_16990	COG0277	FAD linked oxidase domain protein
HBK89_16995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBK89_17020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBK89_17025	COG5380	lipid catabolic process
HBK89_17045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBK89_17095	COG0194	GDP metabolic process
HBK89_17110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBK89_17130	COG3307	-O-antigen
HBK89_17160	COG1061	Type III restriction enzyme res subunit
HBK89_17180	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBK89_17185	COG1704	LemA family
HBK89_17195	COG0493	'glutamate synthase
HBK89_17200	COG0070	glutamate synthase
HBK89_17200	COG0069	glutamate synthase activity
HBK89_17200	COG0067	glutamate synthase
HBK89_17250	COG2226	methyltransferase
HBK89_17265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBK89_17270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBK89_17315	COG0833	amino acid
HBK89_17400	COG0488	(ABC) transporter
HBK89_17405	COG2873	o-acetylhomoserine
HBK89_17410	COG4221	oxidoreductase activity
HBK89_17415	COG0659	secondary active sulfate transmembrane transporter activity
HBK89_17425	COG0745	RESPONSE REGULATOR receiver
HBK89_17440	COG0427	acetyl-CoA hydrolase
HBK89_17470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBK89_17500	COG2329	Antibiotic biosynthesis monooxygenase
HBK89_17515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBK89_17580	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBK89_17585	COG1733	regulation of RNA biosynthetic process
HBK89_17615	COG0667	Aldo Keto reductase
HBK89_17635	COG0583	DNA-binding transcription factor activity
HBK89_17640	COG2814	Major facilitator Superfamily
HBK89_17670	COG1335	isochorismatase
HBK89_17680	COG1012	belongs to the aldehyde dehydrogenase family
HBK89_17685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBK89_17695	COG1113	amino acid transport
HBK89_17705	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBK89_17720	COG2814	Major facilitator Superfamily
HBK89_17730	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBK89_17730	COG0352	thiamine-phosphate diphosphorylase activity
HBK89_17730	COG0351	phosphomethylpyrimidine kinase
HBK89_17750	COG1309	transcriptional regulator
HBK89_17755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBK89_17765	COG3706	GGDEF domain
HBK89_17775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBK89_17785	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBK89_17790	COG3162	membrane
HBK89_17795	COG2205	protein histidine kinase activity
HBK89_17795	COG0784	Response regulator, receiver
HBK89_17795	COG2198	Histidine kinase
HBK89_17820	COG3328	transposase activity
HBK89_17825	COG1522	sequence-specific DNA binding
HBK89_17830	COG1335	isochorismatase
HBK89_17835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBK89_17845	COG0668	transmembrane transport
HBK89_17850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBK89_17855	COG1519	Transferase
HBK89_17860	COG1902	pentaerythritol trinitrate reductase activity
HBK89_17880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBK89_17905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBK89_17905	COG0426	domain, Protein
HBK89_17910	COG4774	siderophore transport
HBK89_17915	COG2119	membrane
HBK89_17925	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBK89_17935	COG4942	peptidase
HBK89_17950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBK89_17960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HBK89_17980	COG0189	ligase activity
HBK89_18000	COG0708	Exodeoxyribonuclease III
HBK89_18005	COG1393	Belongs to the ArsC family
HBK89_18020	COG3706	GGDEF domain
HBK89_18055	COG2351	hydroxyisourate hydrolase activity
HBK89_18060	COG2233	PERMEase
HBK89_18070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBK89_18080	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HBK89_18085	COG1028	Short-chain dehydrogenase reductase Sdr
HBK89_18095	COG3150	esterase
HBK89_18110	COG0791	NLP P60 protein
HBK89_18110	COG1388	LysM domain
HBK89_18115	COG3501	Rhs element vgr protein
HBK89_18125	COG2918	glutathione biosynthetic process
HBK89_18140	COG2733	membrane
HBK89_18145	COG0436	Aminotransferase
HBK89_18150	COG0534	Mate efflux family protein
HBK89_18250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBK89_18255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBK89_18265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBK89_18270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBK89_18285	COG0010	Belongs to the arginase family
HBK89_18315	COG2188	Transcriptional regulator
HBK89_18325	COG0523	cobalamin synthesis protein
HBK89_18335	COG1113	amino acid transport
HBK89_18345	COG0625	glutathione transferase activity
HBK89_18365	COG1683	Conserved Protein
HBK89_18370	COG0534	Mate efflux family protein
HBK89_18375	COG0385	Bile acid
HBK89_18380	COG1335	isochorismatase
HBK89_18385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBK89_18405	COG2116	formate transmembrane transporter activity
HBK89_18410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBK89_18415	COG2133	pyrroloquinoline quinone binding
HBK89_18420	COG2983	Belongs to the UPF0260 family
HBK89_18440	COG1194	a g-specific adenine glycosylase
HBK89_18455	COG2818	Glycosylase
HBK89_18460	COG1064	alcohol dehydrogenase
HBK89_18465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBK89_18480	COG0583	DNA-binding transcription factor activity
HBK89_18485	COG0656	L-ascorbic acid biosynthetic process
HBK89_18490	COG2814	Major facilitator Superfamily
HBK89_18525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBK89_18540	COG2233	PERMEase
HBK89_18545	COG0583	DNA-binding transcription factor activity
HBK89_18580	COG0733	neurotransmitter:sodium symporter activity
HBK89_18620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBK89_18675	COG2951	lytic endotransglycosylase activity
HBK89_18680	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBK89_18695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBK89_18705	COG0671	phosphoesterase, PA-phosphatase related
HBK89_18710	COG0861	Integral membrane protein TerC family
HBK89_18720	COG0754	glutathionylspermidine amidase activity
HBK89_18730	COG0402	S-adenosylhomocysteine deaminase activity
HBK89_18745	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBK89_18750	COG1230	cation diffusion facilitator family transporter
HBK89_18765	COG0706	membrane insertase activity
HBK89_18850	COG2832	Protein of unknown function (DUF454)