locus-tag	class	description
HBM81_00010	COG0592	DNA-directed DNA polymerase activity
HBM81_00020	COG0187	DNA topoisomerase II activity
HBM81_00030	COG0586	Pfam SNARE associated Golgi protein
HBM81_00035	COG0488	(ABC) transporter
HBM81_00060	COG0596	Alpha beta hydrolase
HBM81_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HBM81_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBM81_00110	COG2826	transposase and inactivated derivatives, IS30 family
HBM81_00120	COG0733	neurotransmitter:sodium symporter activity
HBM81_00160	COG2233	PERMEase
HBM81_00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_00210	COG2814	Major facilitator Superfamily
HBM81_00215	COG0656	L-ascorbic acid biosynthetic process
HBM81_00220	COG0583	DNA-binding transcription factor activity
HBM81_00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM81_00240	COG1064	alcohol dehydrogenase
HBM81_00245	COG2818	Glycosylase
HBM81_00260	COG1194	a g-specific adenine glycosylase
HBM81_00280	COG2983	Belongs to the UPF0260 family
HBM81_00285	COG2133	pyrroloquinoline quinone binding
HBM81_00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBM81_00295	COG2116	formate transmembrane transporter activity
HBM81_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM81_00320	COG1335	isochorismatase
HBM81_00325	COG0385	Bile acid
HBM81_00330	COG0534	Mate efflux family protein
HBM81_00335	COG1683	Conserved Protein
HBM81_00355	COG0625	glutathione transferase activity
HBM81_00365	COG1113	amino acid transport
HBM81_00375	COG0523	cobalamin synthesis protein
HBM81_00385	COG2188	Transcriptional regulator
HBM81_00415	COG0010	Belongs to the arginase family
HBM81_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBM81_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBM81_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBM81_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBM81_00550	COG0534	Mate efflux family protein
HBM81_00555	COG0436	Aminotransferase
HBM81_00560	COG2733	membrane
HBM81_00575	COG2918	glutathione biosynthetic process
HBM81_00585	COG3501	Rhs element vgr protein
HBM81_00590	COG1388	LysM domain
HBM81_00590	COG0791	NLP P60 protein
HBM81_00605	COG3150	esterase
HBM81_00615	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HBM81_00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM81_00640	COG2233	PERMEase
HBM81_00645	COG2351	hydroxyisourate hydrolase activity
HBM81_00680	COG3706	GGDEF domain
HBM81_00695	COG1393	Belongs to the ArsC family
HBM81_00700	COG0708	Exodeoxyribonuclease III
HBM81_00720	COG0189	ligase activity
HBM81_00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HBM81_00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBM81_00765	COG4942	peptidase
HBM81_00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBM81_00785	COG2119	membrane
HBM81_00790	COG4774	siderophore transport
HBM81_00795	COG0426	domain, Protein
HBM81_00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM81_00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBM81_00840	COG1902	pentaerythritol trinitrate reductase activity
HBM81_00845	COG1519	Transferase
HBM81_00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBM81_00855	COG0668	transmembrane transport
HBM81_00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM81_00870	COG1335	isochorismatase
HBM81_00875	COG1522	sequence-specific DNA binding
HBM81_00880	COG3328	transposase activity
HBM81_00905	COG0784	Response regulator, receiver
HBM81_00905	COG2198	Histidine kinase
HBM81_00905	COG2205	protein histidine kinase activity
HBM81_00910	COG3162	membrane
HBM81_00915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBM81_00925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM81_00935	COG3706	GGDEF domain
HBM81_00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBM81_00950	COG1309	transcriptional regulator
HBM81_00970	COG0351	phosphomethylpyrimidine kinase
HBM81_00970	COG0352	thiamine-phosphate diphosphorylase activity
HBM81_00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBM81_00980	COG2814	Major facilitator Superfamily
HBM81_00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBM81_01005	COG1113	amino acid transport
HBM81_01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBM81_01020	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_01030	COG1335	isochorismatase
HBM81_01060	COG2814	Major facilitator Superfamily
HBM81_01065	COG0583	DNA-binding transcription factor activity
HBM81_01085	COG0667	Aldo Keto reductase
HBM81_01115	COG1733	regulation of RNA biosynthetic process
HBM81_01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM81_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBM81_01200	COG2329	Antibiotic biosynthesis monooxygenase
HBM81_01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBM81_01260	COG0427	acetyl-CoA hydrolase
HBM81_01275	COG0745	RESPONSE REGULATOR receiver
HBM81_01285	COG0659	secondary active sulfate transmembrane transporter activity
HBM81_01290	COG4221	oxidoreductase activity
HBM81_01295	COG2873	o-acetylhomoserine
HBM81_01300	COG0488	(ABC) transporter
HBM81_01385	COG0833	amino acid
HBM81_01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBM81_01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBM81_01450	COG2226	methyltransferase
HBM81_01500	COG0067	glutamate synthase
HBM81_01500	COG0070	glutamate synthase
HBM81_01500	COG0069	glutamate synthase activity
HBM81_01505	COG0493	'glutamate synthase
HBM81_01515	COG1704	LemA family
HBM81_01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBM81_01540	COG1061	Type III restriction enzyme res subunit
HBM81_01570	COG3307	-O-antigen
HBM81_01590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBM81_01605	COG0194	GDP metabolic process
HBM81_01655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBM81_01675	COG5380	lipid catabolic process
HBM81_01680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBM81_01705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBM81_01710	COG0277	FAD linked oxidase domain protein
HBM81_01720	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBM81_01725	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM81_01740	COG1289	transmembrane transporter activity
HBM81_01750	COG0628	permease
HBM81_01755	COG1192	Involved in chromosome partitioning
HBM81_01785	COG0833	amino acid
HBM81_01790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBM81_01795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBM81_01805	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_01845	COG0583	DNA-binding transcription factor activity
HBM81_01890	COG0517	IMP dehydrogenase activity
HBM81_01895	COG1983	PspC domain protein
HBM81_01915	COG1960	acyl-CoA dehydrogenase activity
HBM81_01930	COG0408	coproporphyrinogen oxidase activity
HBM81_01950	COG0513	Belongs to the DEAD box helicase family
HBM81_01960	COG1127	ABC transporter
HBM81_01965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBM81_01975	COG2854	intermembrane phospholipid transfer
HBM81_01985	COG0598	Magnesium transport protein CorA
HBM81_01995	COG0494	nUDIX hydrolase
HBM81_02000	COG1040	competence protein
HBM81_02005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBM81_02025	COG1946	Acyl-CoA thioesterase
HBM81_02030	COG1301	dicarboxylic acid transport
HBM81_02045	COG1959	2 iron, 2 sulfur cluster binding
HBM81_02050	COG1017	nitric oxide dioxygenase activity
HBM81_02050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM81_02055	COG0433	COG0433 Predicted ATPase
HBM81_02060	COG0626	cystathionine gamma-synthase activity
HBM81_02215	COG1960	acyl-CoA dehydrogenase activity
HBM81_02220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBM81_02250	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBM81_02255	COG0339	signal peptide processing
HBM81_02260	COG0557	exoribonuclease II activity
HBM81_02305	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBM81_02310	COG2169	Transcriptional regulator
HBM81_02315	COG0697	spore germination
HBM81_02320	COG1295	ribonuclease BN
HBM81_02355	COG1702	phosphate starvation-inducible protein PhoH
HBM81_02365	COG0739	heme binding
HBM81_02365	COG1196	nuclear chromosome segregation
HBM81_02365	COG0741	lytic transglycosylase activity
HBM81_02395	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBM81_02400	COG1183	phosphatidylcholine synthase activity
HBM81_02445	COG1960	acyl-CoA dehydrogenase activity
HBM81_02450	COG1309	transcriptional regulator
HBM81_02465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBM81_02470	COG1960	acyl-CoA dehydrogenase activity
HBM81_02490	COG2969	positive regulation of protein catabolic process
HBM81_02500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HBM81_02515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HBM81_02520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBM81_02540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBM81_02550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBM81_02555	COG1408	metallophosphoesterase
HBM81_02565	COG2199	diguanylate cyclase activity
HBM81_02625	COG1607	acyl-coa hydrolase
HBM81_02655	COG2350	Protein conserved in bacteria
HBM81_02665	COG0613	PHP domain protein
HBM81_02670	COG3781	membrane
HBM81_02680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBM81_02685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBM81_02695	COG1862	Preprotein translocase
HBM81_02725	COG2205	protein histidine kinase activity
HBM81_02730	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HBM81_02750	COG0726	polysaccharide deacetylase
HBM81_02755	COG0463	Glycosyl transferase, family 2
HBM81_02760	COG0438	transferase activity, transferring glycosyl groups
HBM81_02825	COG0625	glutathione transferase activity
HBM81_02830	COG0583	DNA-binding transcription factor activity
HBM81_02835	COG1960	acyl-CoA dehydrogenase activity
HBM81_02840	COG1960	acyl-CoA dehydrogenase activity
HBM81_02850	COG2205	protein histidine kinase activity
HBM81_02855	COG0745	RESPONSE REGULATOR receiver
HBM81_02860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HBM81_02880	COG2096	Adenosyltransferase
HBM81_02930	COG0285	dihydrofolate synthase activity
HBM81_02950	COG0450	alkyl hydroperoxide reductase
HBM81_02965	COG0477	Major facilitator Superfamily
HBM81_02970	COG1272	protein, Hemolysin III
HBM81_03005	COG0183	Belongs to the thiolase family
HBM81_03010	COG2207	Transcriptional regulator
HBM81_03030	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM81_03050	COG0183	Belongs to the thiolase family
HBM81_03060	COG2885	chlorophyll binding
HBM81_03060	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBM81_03070	COG1690	Belongs to the RtcB family
HBM81_03075	COG0833	amino acid
HBM81_03085	COG2233	PERMEase
HBM81_03115	COG2094	Belongs to the DNA glycosylase MPG family
HBM81_03120	COG4772	TonB-dependent receptor
HBM81_03135	COG1902	pentaerythritol trinitrate reductase activity
HBM81_03150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM81_03155	COG0354	folic acid binding
HBM81_03165	COG3189	MarR family transcriptional regulator
HBM81_03170	COG2824	Alkylphosphonate utilization operon protein PhnA
HBM81_03175	COG3422	double-strand break repair
HBM81_03215	COG0840	transmembrane signaling receptor activity
HBM81_03235	COG5510	response to toxic substance
HBM81_03245	COG2832	Protein of unknown function (DUF454)
HBM81_03250	COG1376	ErfK ybiS ycfS ynhG family protein
HBM81_03290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBM81_03300	COG1289	transmembrane transporter activity
HBM81_03305	COG2814	Major facilitator Superfamily
HBM81_03325	COG1115	amino acid carrier protein
HBM81_03330	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBM81_03335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBM81_03340	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBM81_03380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBM81_03390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBM81_03395	COG1077	Cell shape determining protein MreB Mrl
HBM81_03400	COG1792	Involved in formation and maintenance of cell shape
HBM81_03405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBM81_03410	COG0424	maF-like protein
HBM81_03415	COG1530	ribonuclease E activity
HBM81_03425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM81_03435	COG0560	Phosphoserine phosphatase
HBM81_03445	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM81_03470	COG2207	Transcriptional regulator
HBM81_03490	COG1113	amino acid transport
HBM81_03495	COG2828	Protein conserved in bacteria
HBM81_03500	COG0142	geranyltranstransferase activity
HBM81_03505	COG2315	Protein conserved in bacteria
HBM81_03520	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBM81_03540	COG2194	sulfuric ester hydrolase activity
HBM81_03545	COG0745	RESPONSE REGULATOR receiver
HBM81_03550	COG0642	Histidine kinase
HBM81_03560	COG0004	ammonium transporteR
HBM81_03565	COG0583	DNA-binding transcription factor activity
HBM81_03585	COG0525	valine-tRNA ligase activity
HBM81_03595	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_03605	COG0393	Putative heavy-metal-binding
HBM81_03610	COG0393	Putative heavy-metal-binding
HBM81_03615	COG1538	Outer membrane efflux protein
HBM81_03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_03630	COG0671	phosphoesterase, PA-phosphatase related
HBM81_03660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBM81_03675	COG1648	precorrin-2 dehydrogenase activity
HBM81_03675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBM81_03680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBM81_03685	COG1733	regulation of RNA biosynthetic process
HBM81_03695	COG0531	amino acid
HBM81_03710	COG0321	lipoyl(octanoyl) transferase activity
HBM81_03715	COG2921	Belongs to the UPF0250 family
HBM81_03755	COG2009	succinate dehydrogenase
HBM81_03760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBM81_03765	COG1053	succinate dehydrogenase
HBM81_03770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBM81_03795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM81_03815	COG2354	Protein conserved in bacteria
HBM81_03820	COG2321	neutral zinc metallopeptidase
HBM81_03835	COG3328	transposase activity
HBM81_03845	COG2843	Capsule synthesis protein
HBM81_03860	COG0589	response to stress
HBM81_03880	COG0505	Belongs to the CarA family
HBM81_03905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBM81_03910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBM81_03960	COG0477	Major facilitator Superfamily
HBM81_03965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBM81_03980	COG1597	lipid kinase activity
HBM81_03985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBM81_04015	COG0584	glycerophosphoryl diester phosphodiesterase
HBM81_04035	COG0741	lytic transglycosylase activity
HBM81_04055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBM81_04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM81_04095	COG0778	Nitroreductase
HBM81_04110	COG1929	Belongs to the glycerate kinase type-1 family
HBM81_04115	COG0243	molybdopterin cofactor binding
HBM81_04120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBM81_04125	COG3339	Conserved Protein
HBM81_04135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HBM81_04150	COG1113	amino acid transport
HBM81_04160	COG0019	diaminopimelate decarboxylase activity
HBM81_04170	COG1280	lysine exporter protein (LysE YggA)
HBM81_04175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBM81_04205	COG0463	Glycosyl transferase, family 2
HBM81_04225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_04260	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBM81_04265	COG1136	(ABC) transporter
HBM81_04270	COG2333	competence protein COMEC
HBM81_04270	COG0658	competence protein
HBM81_04280	COG0616	signal peptide processing
HBM81_04280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HBM81_04285	COG0596	Alpha beta hydrolase
HBM81_04290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBM81_04300	COG0628	permease
HBM81_04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBM81_04355	COG0823	Involved in the tonB-independent uptake of proteins
HBM81_04375	COG0824	Thioesterase
HBM81_04380	COG1473	amidohydrolase
HBM81_04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBM81_04400	COG0047	phosphoribosylformylglycinamidine synthase activity
HBM81_04405	COG2814	Major facilitator Superfamily
HBM81_04415	COG1024	Enoyl-CoA hydratase
HBM81_04420	COG1056	cytidyltransferase-related domain
HBM81_04420	COG1051	belongs to the nudix hydrolase family
HBM81_04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBM81_04445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBM81_04460	COG4625	pathogenesis
HBM81_04465	COG0583	DNA-binding transcription factor activity
HBM81_04470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBM81_04475	COG4208	sulfate ABC transporter
HBM81_04480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBM81_04490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBM81_04495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBM81_04500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBM81_04520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBM81_04535	COG0681	Belongs to the peptidase S26 family
HBM81_04550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBM81_04560	COG1381	Involved in DNA repair and RecF pathway recombination
HBM81_04565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBM81_04575	COG4221	oxidoreductase activity
HBM81_04605	COG0436	Aminotransferase
HBM81_04625	COG0556	nucleotide-excision repair
HBM81_04825	COG5410	chromosome segregation
HBM81_04915	COG1598	PFAM Uncharacterised protein family UPF0150
HBM81_04985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBM81_05005	COG2070	2-Nitropropane dioxygenase
HBM81_05035	COG1215	transferase activity, transferring glycosyl groups
HBM81_05050	COG0415	Belongs to the DNA photolyase family
HBM81_05060	COG1252	NADH dehydrogenase
HBM81_05065	COG1686	Belongs to the peptidase S11 family
HBM81_05080	COG1187	pseudouridine synthase activity
HBM81_05280	COG5410	chromosome segregation
HBM81_05390	COG3561	AntA/AntB antirepressor
HBM81_05450	COG0582	viral genome integration into host DNA
HBM81_05475	COG0477	Major facilitator Superfamily
HBM81_05480	COG0583	DNA-binding transcription factor activity
HBM81_05495	COG0612	Peptidase, M16
HBM81_05520	COG0352	thiamine-phosphate diphosphorylase activity
HBM81_05555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM81_05570	COG1309	transcriptional regulator
HBM81_05580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBM81_05585	COG0076	glutamate decarboxylase activity
HBM81_05595	COG1522	sequence-specific DNA binding
HBM81_05600	COG3961	Belongs to the TPP enzyme family
HBM81_05605	COG1113	amino acid transport
HBM81_05610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBM81_05615	COG0573	inorganic phosphate transmembrane transporter activity
HBM81_05625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBM81_05630	COG0616	signal peptide processing
HBM81_05640	COG3328	transposase activity
HBM81_05670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBM81_05675	COG1686	Belongs to the peptidase S11 family
HBM81_05700	COG0583	DNA-binding transcription factor activity
HBM81_05705	COG1067	ATP-dependent peptidase activity
HBM81_05750	COG1966	Carbon starvation protein
HBM81_05755	COG2879	small protein
HBM81_05790	COG2508	Transcriptional regulator
HBM81_05790	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBM81_05810	COG1113	amino acid transport
HBM81_05815	COG0583	DNA-binding transcription factor activity
HBM81_05820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM81_05825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM81_05835	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_05840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM81_05845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM81_05845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HBM81_05880	COG2814	Major facilitator Superfamily
HBM81_05885	COG4948	Mandelate Racemase Muconate Lactonizing
HBM81_05895	COG1309	transcriptional regulator
HBM81_05915	COG1741	Belongs to the pirin family
HBM81_05925	COG2964	Protein conserved in bacteria
HBM81_05940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM81_05945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBM81_05950	COG4605	iron ion homeostasis
HBM81_05955	COG4604	ABC transporter, ATP-binding protein
HBM81_05960	COG4607	ABC-type enterochelin transport system periplasmic component
HBM81_05965	COG4774	siderophore transport
HBM81_05975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBM81_05980	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBM81_05985	COG1535	isochorismatase
HBM81_05985	COG3433	isochorismatase activity
HBM81_06000	COG1132	(ABC) transporter
HBM81_06010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBM81_06020	COG1169	isochorismate synthase
HBM81_06035	COG3739	integral membrane protein
HBM81_06070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HBM81_06100	COG0308	aminopeptidase N
HBM81_06105	COG0512	Glutamine amidotransferase of anthranilate synthase
HBM81_06285	COG5410	chromosome segregation
HBM81_06405	COG0739	heme binding
HBM81_06455	COG0582	viral genome integration into host DNA
HBM81_06465	COG3104	oligopeptide transport
HBM81_06470	COG0174	glutamine synthetase
HBM81_06480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBM81_06515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBM81_06520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBM81_06525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBM81_06545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBM81_06550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBM81_06555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBM81_06570	COG1960	acyl-CoA dehydrogenase activity
HBM81_06575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBM81_06580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM81_06590	COG2223	nitrite transmembrane transporter activity
HBM81_06600	COG0024	Methionine aminopeptidase
HBM81_06605	COG0052	Belongs to the universal ribosomal protein uS2 family
HBM81_06620	COG2207	Transcriptional regulator
HBM81_06645	COG2951	lytic endotransglycosylase activity
HBM81_06650	COG0772	Belongs to the SEDS family
HBM81_06665	COG0842	Transport permease protein
HBM81_06670	COG1131	(ABC) transporter
HBM81_06715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_06730	COG4215	(ABC) transporter
HBM81_06735	COG4160	amino acid transport
HBM81_06740	COG4598	ABC transporter
HBM81_06750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBM81_06760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM81_06775	COG1720	tRNA m6t6A37 methyltransferase activity
HBM81_06795	COG0745	RESPONSE REGULATOR receiver
HBM81_06800	COG0642	Histidine kinase
HBM81_06810	COG0494	nUDIX hydrolase
HBM81_06820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBM81_06825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBM81_06830	COG3139	Protein of unknown function (DUF1315)
HBM81_06835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBM81_06840	COG1301	dicarboxylic acid transport
HBM81_06845	COG1960	acyl-CoA dehydrogenase activity
HBM81_06850	COG2819	hydrolase of the alpha beta superfamily
HBM81_06860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HBM81_06870	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBM81_06875	COG1234	tRNA 3'-trailer cleavage
HBM81_06905	COG2363	Small membrane protein
HBM81_06925	COG0513	Belongs to the DEAD box helicase family
HBM81_06935	COG0778	Nitroreductase
HBM81_06965	COG1286	toxin biosynthetic process
HBM81_06990	COG4783	chaperone-mediated protein folding
HBM81_06995	COG1610	YqeY-like protein
HBM81_07095	COG3111	PFAM Bacterial OB fold (BOF) protein
HBM81_07120	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBM81_07125	COG0786	glutamate:sodium symporter activity
HBM81_07135	COG2186	Transcriptional regulator
HBM81_07185	COG0477	Major facilitator Superfamily
HBM81_07210	COG2985	domain, Protein
HBM81_07220	COG2995	paraquat-inducible protein a
HBM81_07225	COG3008	intermembrane lipid transfer
HBM81_07225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBM81_07245	COG0482	sulfurtransferase activity
HBM81_07265	COG3173	Aminoglycoside phosphotransferase
HBM81_07275	COG2433	Pfam Transposase IS66
HBM81_07315	COG1301	dicarboxylic acid transport
HBM81_07325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM81_07330	COG2011	ABC-type metal ion transport system permease component
HBM81_07335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBM81_07340	COG1464	Belongs to the NlpA lipoprotein family
HBM81_07345	COG0151	Belongs to the GarS family
HBM81_07350	COG0138	bifunctional purine biosynthesis protein purh
HBM81_07355	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HBM81_07385	COG2308	Evidence 4 Homologs of previously reported genes of
HBM81_07395	COG1305	Transglutaminase-like
HBM81_07405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBM81_07410	COG0305	Participates in initiation and elongation during chromosome replication
HBM81_07435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBM81_07445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBM81_07450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBM81_07475	COG0726	polysaccharide deacetylase
HBM81_07475	COG1649	PFAM Uncharacterised BCR, COG1649
HBM81_07480	COG1215	transferase activity, transferring glycosyl groups
HBM81_07485	COG3658	cytochrome
HBM81_07495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM81_07510	COG0583	DNA-binding transcription factor activity
HBM81_07530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM81_07535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM81_07550	COG1960	acyl-CoA dehydrogenase activity
HBM81_07555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM81_07560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM81_07585	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HBM81_07590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HBM81_07600	COG2205	protein histidine kinase activity
HBM81_07605	COG0745	RESPONSE REGULATOR receiver
HBM81_07610	COG0174	glutamine synthetase
HBM81_07630	COG0729	surface antigen
HBM81_07655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBM81_07660	COG2814	Major facilitator Superfamily
HBM81_07675	COG0583	DNA-binding transcription factor activity
HBM81_07690	COG1187	pseudouridine synthase activity
HBM81_07710	COG0802	atpase or kinase
HBM81_07715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBM81_07725	COG1923	regulation of RNA biosynthetic process
HBM81_07730	COG0697	spore germination
HBM81_07745	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM81_07755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBM81_07760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBM81_07760	COG0519	Catalyzes the synthesis of GMP from XMP
HBM81_07765	COG4302	ethanolamine ammonia-lyase activity
HBM81_07770	COG4303	Ethanolamine ammonia lyase large subunit
HBM81_07775	COG0531	amino acid
HBM81_07795	COG1454	alcohol dehydrogenase
HBM81_07800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBM81_07810	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBM81_07830	COG0308	aminopeptidase N
HBM81_07860	COG1605	Chorismate mutase
HBM81_07875	COG1309	transcriptional regulator
HBM81_07885	COG0668	transmembrane transport
HBM81_07920	COG4773	Receptor
HBM81_07940	COG0488	(ABC) transporter
HBM81_07945	COG0589	response to stress
HBM81_07970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBM81_07980	COG3135	benzoate transporter
HBM81_07985	COG1522	sequence-specific DNA binding
HBM81_07995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBM81_08000	COG0583	DNA-binding transcription factor activity
HBM81_08010	COG0183	Belongs to the thiolase family
HBM81_08020	COG2030	dehydratase
HBM81_08040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBM81_08050	COG0824	Thioesterase
HBM81_08055	COG1454	alcohol dehydrogenase
HBM81_08065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBM81_08085	COG0069	glutamate synthase activity
HBM81_08105	COG2814	Major facilitator Superfamily
HBM81_08120	COG0511	ligase activity, forming carbon-carbon bonds
HBM81_08140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM81_08140	COG1116	anion transmembrane transporter activity
HBM81_08145	COG0745	RESPONSE REGULATOR receiver
HBM81_08155	COG2146	nitrite reductase [NAD(P)H] activity
HBM81_08155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM81_08160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM81_08165	COG0243	molybdopterin cofactor binding
HBM81_08175	COG0243	molybdopterin cofactor binding
HBM81_08180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBM81_08195	COG0315	cyclic pyranopterin monophosphate synthase activity
HBM81_08195	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBM81_08200	COG0303	'Molybdopterin
HBM81_08210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM81_08215	COG0697	spore germination
HBM81_08235	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBM81_08240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBM81_08295	COG2204	response regulator
HBM81_08300	COG3852	Histidine kinase
HBM81_08320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBM81_08325	COG0575	Belongs to the CDS family
HBM81_08360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM81_08375	COG2137	regulation of response to DNA damage stimulus
HBM81_08385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBM81_08390	COG1011	Hydrolase
HBM81_08415	COG1522	sequence-specific DNA binding
HBM81_08425	COG1113	amino acid transport
HBM81_08440	COG0659	secondary active sulfate transmembrane transporter activity
HBM81_08445	COG2135	peptidase activity
HBM81_08460	COG5001	Diguanylate cyclase
HBM81_08460	COG3300	MHYT domain
HBM81_08480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBM81_08480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBM81_08480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBM81_08485	COG1105	Belongs to the carbohydrate kinase PfkB family
HBM81_08490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBM81_08490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBM81_08520	COG0024	Methionine aminopeptidase
HBM81_08525	COG0583	DNA-binding transcription factor activity
HBM81_08535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBM81_08540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBM81_08545	COG0516	GMP reductase activity
HBM81_08545	COG0517	IMP dehydrogenase activity
HBM81_08570	COG0552	protein localization to endoplasmic reticulum
HBM81_08580	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HBM81_08595	COG4890	Cyd operon protein YbgT
HBM81_08600	COG1294	oxidase, subunit
HBM81_08615	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBM81_08625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBM81_08630	COG4774	siderophore transport
HBM81_08645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBM81_08650	COG0569	domain protein
HBM81_08655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBM81_08685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HBM81_08690	COG0542	response to heat
HBM81_08715	COG1902	pentaerythritol trinitrate reductase activity
HBM81_08715	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM81_08760	COG2323	membrane
HBM81_08765	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HBM81_08775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM81_08780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM81_08785	COG0183	Belongs to the thiolase family
HBM81_08790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBM81_08795	COG0596	Alpha beta hydrolase
HBM81_08800	COG2271	Major facilitator Superfamily
HBM81_08805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBM81_08810	COG3485	protocatechuate 3,4-dioxygenase
HBM81_08815	COG3485	protocatechuate 3,4-dioxygenase
HBM81_08820	COG0710	3-dehydroquinate dehydratase activity
HBM81_08825	COG3420	alginic acid biosynthetic process
HBM81_08830	COG3659	wide pore channel activity
HBM81_08835	COG4993	Dehydrogenase
HBM81_08845	COG2391	methyltransferase activity
HBM81_08860	COG1414	Transcriptional regulator
HBM81_08865	COG0583	DNA-binding transcription factor activity
HBM81_08870	COG1960	acyl-CoA dehydrogenase activity
HBM81_08895	COG2814	Major facilitator Superfamily
HBM81_08905	COG0154	amidase activity
HBM81_08925	COG4638	Rieske (2fe-2S)
HBM81_08935	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_08945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM81_08955	COG3733	amine oxidase
HBM81_08965	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_08975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM81_08980	COG0183	Belongs to the thiolase family
HBM81_08985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM81_08990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM81_09000	COG4829	muconolactone delta-isomerase
HBM81_09005	COG4948	Mandelate Racemase Muconate Lactonizing
HBM81_09010	COG0583	DNA-binding transcription factor activity
HBM81_09020	COG2186	Transcriptional regulator
HBM81_09040	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_09060	COG1960	acyl-CoA dehydrogenase activity
HBM81_09065	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_09070	COG3829	transcription factor binding
HBM81_09080	COG3162	membrane
HBM81_09095	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_09110	COG0753	catalase activity
HBM81_09130	COG1846	Transcriptional regulator
HBM81_09135	COG1902	pentaerythritol trinitrate reductase activity
HBM81_09135	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM81_09145	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBM81_09175	COG1309	transcriptional regulator
HBM81_09185	COG1335	isochorismatase
HBM81_09190	COG0583	DNA-binding transcription factor activity
HBM81_09200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM81_09200	COG0475	glutathione-regulated potassium exporter activity
HBM81_09210	COG1473	amidohydrolase
HBM81_09220	COG2831	hemolysin activation secretion protein
HBM81_09225	COG3210	domain, Protein
HBM81_09255	COG2188	Transcriptional regulator
HBM81_09270	COG0583	DNA-binding transcription factor activity
HBM81_09300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBM81_09320	COG1566	PFAM secretion protein HlyD family protein
HBM81_09335	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_09340	COG0129	dihydroxy-acid dehydratase activity
HBM81_09350	COG0583	DNA-binding transcription factor activity
HBM81_09355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBM81_09365	COG2084	Dehydrogenase
HBM81_09370	COG2207	Transcriptional regulator
HBM81_09385	COG1064	alcohol dehydrogenase
HBM81_09400	COG1120	ATPase activity
HBM81_09420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBM81_09535	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HBM81_09585	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_09600	COG2207	Transcriptional regulator
HBM81_09610	COG2205	protein histidine kinase activity
HBM81_09615	COG0745	RESPONSE REGULATOR receiver
HBM81_09620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_09625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBM81_09630	COG1538	Outer membrane efflux protein
HBM81_09640	COG2072	flavoprotein involved in K transport
HBM81_09660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM81_09680	COG3539	Fimbrial protein
HBM81_09710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HBM81_09720	COG0753	catalase activity
HBM81_09735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBM81_09800	COG3433	isochorismatase activity
HBM81_09800	COG1535	isochorismatase
HBM81_09805	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_09810	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBM81_09815	COG4149	molybdate abc transporter
HBM81_09820	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBM81_09830	COG4638	Rieske (2fe-2S)
HBM81_09835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBM81_09840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM81_09840	COG0543	2 iron, 2 sulfur cluster binding
HBM81_09865	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_09880	COG2207	Transcriptional regulator
HBM81_09890	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_09895	COG2610	gluconate transmembrane transporter activity
HBM81_09905	COG0583	DNA-binding transcription factor activity
HBM81_09915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM81_09920	COG2031	fatty acid transporter
HBM81_09925	COG0183	Belongs to the thiolase family
HBM81_09930	COG0583	DNA-binding transcription factor activity
HBM81_09935	COG0583	DNA-binding transcription factor activity
HBM81_09950	COG1027	Aspartate ammonia-lyase
HBM81_09960	COG0477	Major facilitator Superfamily
HBM81_09980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM81_09985	COG4521	taurine ABC transporter
HBM81_10000	COG2188	Transcriptional regulator
HBM81_10010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBM81_10015	COG1733	regulation of RNA biosynthetic process
HBM81_10020	COG3708	Transcriptional regulator
HBM81_10020	COG2207	Transcriptional regulator
HBM81_10035	COG0730	response to heat
HBM81_10045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM81_10045	COG3453	Protein conserved in bacteria
HBM81_10060	COG1063	alcohol dehydrogenase
HBM81_10070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBM81_10075	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBM81_10080	COG0022	dehydrogenase e1 component
HBM81_10085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBM81_10090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBM81_10105	COG3706	GGDEF domain
HBM81_10120	COG0133	tryptophan synthase activity
HBM81_10130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBM81_10165	COG2826	transposase and inactivated derivatives, IS30 family
HBM81_10175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBM81_10200	COG2226	methyltransferase
HBM81_10255	COG0842	Transport permease protein
HBM81_10260	COG0842	Transport permease protein
HBM81_10265	COG1131	(ABC) transporter
HBM81_10280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBM81_10285	COG4773	Receptor
HBM81_10305	COG0730	response to heat
HBM81_10310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBM81_10330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HBM81_10385	COG4264	IucA IucC family
HBM81_10390	COG4264	IucA IucC family
HBM81_10410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBM81_10425	COG1960	acyl-CoA dehydrogenase activity
HBM81_10430	COG1960	acyl-CoA dehydrogenase activity
HBM81_10435	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBM81_10440	COG2207	Transcriptional regulator
HBM81_10445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBM81_10450	COG0776	regulation of translation
HBM81_10475	COG0822	iron-sulfur transferase activity
HBM81_10480	COG0316	Belongs to the HesB IscA family
HBM81_10510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBM81_10530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBM81_10535	COG0702	epimerase
HBM81_10570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBM81_10580	COG0339	signal peptide processing
HBM81_10630	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBM81_10635	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBM81_10665	COG0776	regulation of translation
HBM81_10730	COG0084	hydrolase, TatD family'
HBM81_10750	COG1663	tetraacyldisaccharide 4'-kinase activity
HBM81_10755	COG1132	(ABC) transporter
HBM81_10765	COG0811	peptide transport
HBM81_10770	COG1475	DNA binding
HBM81_10775	COG1192	Involved in chromosome partitioning
HBM81_10785	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBM81_10800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBM81_10805	COG0191	fructose-bisphosphate aldolase activity
HBM81_10825	COG0424	maF-like protein
HBM81_10830	COG2850	peptidyl-arginine hydroxylation
HBM81_10840	COG0640	Transcriptional regulator
HBM81_10855	COG3619	membrane
HBM81_10860	COG3122	Protein conserved in bacteria
HBM81_10865	COG1132	(ABC) transporter
HBM81_10885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBM81_10890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBM81_10900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBM81_10900	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBM81_10900	COG0506	proline dehydrogenase activity
HBM81_10905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBM81_10920	COG3698	Phosphodiester glycosidase
HBM81_10930	COG2353	YceI-like domain
HBM81_10940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBM81_10985	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBM81_10985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBM81_11010	COG3539	Fimbrial protein
HBM81_11015	COG3121	Chaperone
HBM81_11040	COG0697	spore germination
HBM81_11050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBM81_11060	COG0583	DNA-binding transcription factor activity
HBM81_11080	COG1309	transcriptional regulator
HBM81_11095	COG1522	sequence-specific DNA binding
HBM81_11105	COG1126	abc transporter atp-binding protein
HBM81_11110	COG0765	amino acid transport
HBM81_11115	COG0765	amino acid transport
HBM81_11145	COG1464	Belongs to the NlpA lipoprotein family
HBM81_11155	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBM81_11160	COG2011	ABC-type metal ion transport system permease component
HBM81_11165	COG0012	GTP binding
HBM81_11190	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBM81_11230	COG0386	Belongs to the glutathione peroxidase family
HBM81_11240	COG0436	Aminotransferase
HBM81_11280	COG3634	alkyl hydroperoxide reductase activity
HBM81_11295	COG0583	DNA-binding transcription factor activity
HBM81_11300	COG0798	PFAM Bile acid sodium symporter
HBM81_11305	COG0640	Transcriptional regulator
HBM81_11320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBM81_11330	COG0583	DNA-binding transcription factor activity
HBM81_11340	COG1953	Uracil, thiamine, allantoin
HBM81_11350	COG2175	clavaminate synthase activity
HBM81_11355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM81_11360	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBM81_11365	COG4521	taurine ABC transporter
HBM81_11375	COG0477	Major facilitator Superfamily
HBM81_11395	COG1271	oxidase subunit
HBM81_11400	COG1294	oxidase, subunit
HBM81_11410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBM81_11430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBM81_11450	COG3052	prosthetic group binding
HBM81_11455	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HBM81_11465	COG2814	Major facilitator Superfamily
HBM81_11485	COG1346	cytolysis
HBM81_11495	COG0583	DNA-binding transcription factor activity
HBM81_11500	COG0625	glutathione transferase activity
HBM81_11505	COG0625	glutathione transferase activity
HBM81_11510	COG0583	DNA-binding transcription factor activity
HBM81_11525	COG1045	serine acetyltransferase
HBM81_11530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBM81_11535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBM81_11545	COG1280	lysine exporter protein (LysE YggA)
HBM81_11560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM81_11565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM81_11570	COG1126	abc transporter atp-binding protein
HBM81_11575	COG0765	amino acid transport
HBM81_11580	COG0765	amino acid transport
HBM81_11600	COG0784	Response regulator, receiver
HBM81_11600	COG2205	protein histidine kinase activity
HBM81_11620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBM81_11640	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_11690	COG0583	DNA-binding transcription factor activity
HBM81_11710	COG0318	PFAM AMP-dependent synthetase and ligase
HBM81_11715	COG1309	transcriptional regulator
HBM81_11720	COG1960	acyl-CoA dehydrogenase activity
HBM81_11725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBM81_11730	COG1024	Enoyl-CoA hydratase
HBM81_11735	COG4770	biotin carboxylase activity
HBM81_11745	COG0583	DNA-binding transcription factor activity
HBM81_11760	COG1960	acyl-CoA dehydrogenase activity
HBM81_11770	COG2814	Major facilitator Superfamily
HBM81_11780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBM81_11785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBM81_11790	COG2814	Major facilitator Superfamily
HBM81_11795	COG1960	acyl-CoA dehydrogenase activity
HBM81_11800	COG1024	Enoyl-CoA hydratase
HBM81_11805	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_11810	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM81_11815	COG0183	Belongs to the thiolase family
HBM81_11825	COG2814	Major facilitator Superfamily
HBM81_11835	COG1024	Enoyl-CoA hydratase
HBM81_11850	COG1960	acyl-CoA dehydrogenase activity
HBM81_11855	COG2814	Major facilitator Superfamily
HBM81_11860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBM81_11865	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBM81_11880	COG3842	ATPase activity
HBM81_11885	COG1840	ABC-type Fe3 transport system, periplasmic component
HBM81_11895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM81_11900	COG1414	Transcriptional regulator
HBM81_11910	COG0583	DNA-binding transcription factor activity
HBM81_11915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBM81_11920	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_11930	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBM81_11940	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_11945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM81_11950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM81_11955	COG2267	carboxylic ester hydrolase activity
HBM81_11975	COG3038	cytochrome b561
HBM81_11980	COG0753	catalase activity
HBM81_12015	COG2050	protein possibly involved in aromatic compounds catabolism
HBM81_12025	COG3327	negative regulation of DNA-templated transcription, initiation
HBM81_12030	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBM81_12035	COG0183	Belongs to the thiolase family
HBM81_12040	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM81_12045	COG1024	Enoyl-CoA hydratase
HBM81_12050	COG1024	Enoyl-CoA hydratase
HBM81_12055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBM81_12060	COG2151	metal-sulfur cluster biosynthetic enzyme
HBM81_12065	COG3396	Phenylacetate-CoA oxygenase
HBM81_12070	COG3460	Phenylacetate-CoA oxygenase
HBM81_12075	COG3396	Phenylacetate-CoA oxygenase
HBM81_12080	COG2030	dehydratase
HBM81_12080	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_12085	COG1760	l-serine dehydratase
HBM81_12090	COG0531	amino acid
HBM81_12095	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_12110	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM81_12120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBM81_12140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM81_12150	COG0789	Transcriptional regulator
HBM81_12165	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBM81_12180	COG2807	transmembrane transport
HBM81_12185	COG0590	tRNA wobble adenosine to inosine editing
HBM81_12300	COG1116	anion transmembrane transporter activity
HBM81_12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBM81_12315	COG0864	Transcriptional regulator
HBM81_12335	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBM81_12340	COG0439	Biotin carboxylase
HBM81_12355	COG1063	alcohol dehydrogenase
HBM81_12365	COG1309	transcriptional regulator
HBM81_12385	COG0038	chloride channel
HBM81_12390	COG4770	biotin carboxylase activity
HBM81_12410	COG1914	H( )-stimulated, divalent metal cation uptake system
HBM81_12415	COG0583	DNA-binding transcription factor activity
HBM81_12430	COG3209	COG3209 Rhs family protein
HBM81_12435	COG3501	Rhs element vgr protein
HBM81_12465	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBM81_12485	COG2814	Major facilitator Superfamily
HBM81_12495	COG1560	Kdo2-lipid A biosynthetic process
HBM81_12505	COG5006	permease, DMT superfamily
HBM81_12510	COG1522	sequence-specific DNA binding
HBM81_12525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HBM81_12535	COG4122	O-methyltransferase activity
HBM81_12565	COG1538	Outer membrane efflux protein
HBM81_12575	COG1137	ATPase activity
HBM81_12580	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBM81_12590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBM81_12595	COG0517	IMP dehydrogenase activity
HBM81_12595	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HBM81_12635	COG2814	Major facilitator Superfamily
HBM81_12670	COG1278	Cold shock
HBM81_12675	COG1280	lysine exporter protein (LysE YggA)
HBM81_12710	COG1570	exodeoxyribonuclease VII activity
HBM81_12760	COG0583	DNA-binding transcription factor activity
HBM81_12765	COG4638	Rieske (2fe-2S)
HBM81_12770	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBM81_12775	COG0543	2 iron, 2 sulfur cluster binding
HBM81_12775	COG0633	Ferredoxin
HBM81_12780	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_12785	COG3135	benzoate transporter
HBM81_12790	COG2814	Major facilitator Superfamily
HBM81_12805	COG1643	Atp-dependent helicase
HBM81_12810	COG0450	alkyl hydroperoxide reductase
HBM81_12820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HBM81_12830	COG3634	alkyl hydroperoxide reductase activity
HBM81_12850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HBM81_12855	COG0625	glutathione transferase activity
HBM81_12865	COG2885	chlorophyll binding
HBM81_12900	COG0542	response to heat
HBM81_12915	COG1765	OsmC-like protein
HBM81_12930	COG0667	Aldo Keto reductase
HBM81_12945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBM81_12955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBM81_12965	COG0527	aspartate kinase activity
HBM81_12975	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBM81_12985	COG3038	cytochrome b561
HBM81_12990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HBM81_12995	COG2252	PERMEase
HBM81_13005	COG2072	flavoprotein involved in K transport
HBM81_13020	COG1741	Belongs to the pirin family
HBM81_13025	COG1309	transcriptional regulator
HBM81_13050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBM81_13075	COG5001	Diguanylate cyclase
HBM81_13075	COG4251	negative regulation of phosphorylation
HBM81_13075	COG3706	GGDEF domain
HBM81_13075	COG2203	Gaf domain
HBM81_13085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBM81_13105	COG4172	Belongs to the ABC transporter superfamily
HBM81_13110	COG4239	(ABC) transporter, permease
HBM81_13115	COG4174	ABC transporter (Permease)
HBM81_13125	COG1388	LysM domain
HBM81_13125	COG1388	LysM domain
HBM81_13125	COG0741	lytic transglycosylase activity
HBM81_13125	COG0741	lytic transglycosylase activity
HBM81_13130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBM81_13170	COG0583	DNA-binding transcription factor activity
HBM81_13175	COG1279	arginine transmembrane transporter activity
HBM81_13195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM81_13200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM81_13205	COG0006	proline dipeptidase activity
HBM81_13240	COG2194	sulfuric ester hydrolase activity
HBM81_13285	COG0739	heme binding
HBM81_13610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBM81_13635	COG3384	dioxygenase
HBM81_13645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBM81_13650	COG2878	Part of a membrane complex involved in electron transport
HBM81_13655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBM81_13680	COG0768	penicillin binding
HBM81_13685	COG0742	ribosomal rna small subunit methyltransferase
HBM81_13700	COG0830	nickel cation binding
HBM81_13710	COG0804	urea catabolic process
HBM81_13750	COG1253	flavin adenine dinucleotide binding
HBM81_13755	COG2851	Citrate transporter
HBM81_13810	COG1773	rubredoxin
HBM81_13815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBM81_13825	COG0583	DNA-binding transcription factor activity
HBM81_13850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBM81_13855	COG4181	ATPase activity
HBM81_13900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBM81_13920	COG0306	phosphate transporter
HBM81_13930	COG3958	Transketolase
HBM81_13935	COG3959	Transketolase, thiamine diphosphate binding domain
HBM81_13940	COG2271	Major facilitator Superfamily
HBM81_13945	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_13950	COG0583	DNA-binding transcription factor activity
HBM81_13965	COG2223	nitrite transmembrane transporter activity
HBM81_13970	COG2207	Transcriptional regulator
HBM81_13975	COG2066	Belongs to the glutaminase family
HBM81_13980	COG0242	peptide deformylase activity
HBM81_13985	COG0477	Major facilitator Superfamily
HBM81_13995	COG0028	Belongs to the TPP enzyme family
HBM81_14010	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_14015	COG2267	carboxylic ester hydrolase activity
HBM81_14025	COG2271	Major facilitator Superfamily
HBM81_14030	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBM81_14040	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_14060	COG1414	Transcriptional regulator
HBM81_14075	COG1024	Enoyl-CoA hydratase
HBM81_14085	COG1215	transferase activity, transferring glycosyl groups
HBM81_14090	COG0726	polysaccharide deacetylase
HBM81_14090	COG1649	PFAM Uncharacterised BCR, COG1649
HBM81_14100	COG4681	YaeQ
HBM81_14110	COG0523	cobalamin synthesis protein
HBM81_14120	COG1607	acyl-coa hydrolase
HBM81_14130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM81_14135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBM81_14140	COG1309	transcriptional regulator
HBM81_14165	COG2040	homocysteine
HBM81_14170	COG0531	amino acid
HBM81_14225	COG1595	DNA-templated transcription, initiation
HBM81_14235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM81_14240	COG0477	Major facilitator Superfamily
HBM81_14260	COG0084	hydrolase, TatD family'
HBM81_14295	COG0629	single-stranded DNA binding
HBM81_14350	COG0582	viral genome integration into host DNA
HBM81_14445	COG0592	DNA-directed DNA polymerase activity
HBM81_14485	COG2026	Addiction module toxin, RelE StbE family
HBM81_14665	COG0405	Gamma-glutamyltransferase
HBM81_14670	COG2814	Major facilitator Superfamily
HBM81_14680	COG2050	protein possibly involved in aromatic compounds catabolism
HBM81_14695	COG1090	epimerase
HBM81_14715	COG0420	3'-5' exonuclease activity
HBM81_14740	COG0735	belongs to the Fur family
HBM81_14745	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBM81_14765	COG0121	glutamine amidotransferase
HBM81_14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBM81_14790	COG0210	DNA helicase
HBM81_14795	COG2885	chlorophyll binding
HBM81_14800	COG0204	Acyl-transferase
HBM81_14815	COG2894	cell division
HBM81_14840	COG1280	lysine exporter protein (LysE YggA)
HBM81_14845	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBM81_14845	COG1674	ftsk spoiiie
HBM81_14850	COG0492	ferredoxin-NADP+ reductase activity
HBM81_14855	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HBM81_14865	COG0456	acetyltransferase
HBM81_14925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HBM81_14925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBM81_14945	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_14965	COG0473	3-isopropylmalate dehydrogenase activity
HBM81_14970	COG0583	DNA-binding transcription factor activity
HBM81_14990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBM81_15015	COG0564	pseudouridine synthase activity
HBM81_15025	COG0358	DNA primase activity
HBM81_15040	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HBM81_15070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBM81_15100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBM81_15110	COG0352	thiamine-phosphate diphosphorylase activity
HBM81_15110	COG0351	phosphomethylpyrimidine kinase
HBM81_15110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBM81_15115	COG1652	LysM domain
HBM81_15140	COG1399	metal-binding, possibly nucleic acid-binding protein
HBM81_15145	COG3101	peptidyl-lysine hydroxylation
HBM81_15150	COG0009	L-threonylcarbamoyladenylate synthase
HBM81_15155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBM81_15160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBM81_15175	COG4106	trans-aconitate 2-methyltransferase activity
HBM81_15190	COG0596	Alpha beta hydrolase
HBM81_15190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM81_15190	COG2226	methyltransferase
HBM81_15195	COG1877	trehalose-phosphatase activity
HBM81_15200	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HBM81_15205	COG2223	nitrite transmembrane transporter activity
HBM81_15225	COG1196	nuclear chromosome segregation
HBM81_15235	COG0730	response to heat
HBM81_15250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBM81_15260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBM81_15310	COG0489	protein tyrosine kinase activity
HBM81_15320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM81_15320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM81_15350	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBM81_15355	COG2081	HI0933 family
HBM81_15365	COG0668	transmembrane transport
HBM81_15385	COG0583	DNA-binding transcription factor activity
HBM81_15405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBM81_15410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBM81_15440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HBM81_15475	COG2205	protein histidine kinase activity
HBM81_15480	COG0745	RESPONSE REGULATOR receiver
HBM81_15500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBM81_15510	COG2205	protein histidine kinase activity
HBM81_15580	COG4993	Dehydrogenase
HBM81_15600	COG0384	phenazine biosynthesis protein PhzF
HBM81_15620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBM81_15635	COG0583	DNA-binding transcription factor activity
HBM81_15655	COG1473	amidohydrolase
HBM81_15665	COG0583	DNA-binding transcription factor activity
HBM81_15680	COG0583	DNA-binding transcription factor activity
HBM81_15685	COG1053	succinate dehydrogenase
HBM81_15695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HBM81_15700	COG2814	Major facilitator Superfamily
HBM81_15705	COG1960	acyl-CoA dehydrogenase activity
HBM81_15710	COG0583	DNA-binding transcription factor activity
HBM81_15715	COG1063	alcohol dehydrogenase
HBM81_15745	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBM81_15750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBM81_15755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBM81_15770	COG3667	copper resistance
HBM81_15775	COG2132	Multicopper oxidase
HBM81_15785	COG0561	phosphatase activity
HBM81_15790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBM81_15815	COG1214	PFAM Peptidase M22, glycoprotease
HBM81_15870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBM81_15880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBM81_15885	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HBM81_15890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBM81_15950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBM81_15960	COG1846	Transcriptional regulator
HBM81_15965	COG1764	response to oxidative stress
HBM81_16015	COG0037	tRNA processing
HBM81_16025	COG0248	Ppx GppA phosphatase
HBM81_16055	COG0072	phenylalanine-tRNA ligase activity
HBM81_16095	COG1238	metal cluster binding
HBM81_16100	COG0625	glutathione transferase activity
HBM81_16115	COG0318	PFAM AMP-dependent synthetase and ligase
HBM81_16120	COG3028	Belongs to the UPF0307 family
HBM81_16125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBM81_16145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBM81_16150	COG0617	tRNA 3'-terminal CCA addition
HBM81_16155	COG1555	photosystem II stabilization
HBM81_16160	COG3956	TIGRFAM MazG family protein
HBM81_16170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBM81_16190	COG5002	protein histidine kinase activity
HBM81_16190	COG2205	protein histidine kinase activity
HBM81_16190	COG0784	Response regulator, receiver
HBM81_16195	COG1024	Enoyl-CoA hydratase
HBM81_16200	COG2084	Dehydrogenase
HBM81_16205	COG3622	Belongs to the hyi family
HBM81_16235	COG0697	spore germination
HBM81_16245	COG2814	Major facilitator Superfamily
HBM81_16250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBM81_16260	COG0583	DNA-binding transcription factor activity
HBM81_16270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBM81_16285	COG0084	hydrolase, TatD family'
HBM81_16300	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBM81_16330	COG0440	acetolactate synthase activity
HBM81_16335	COG0028	Belongs to the TPP enzyme family
HBM81_16360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBM81_16365	COG0577	efflux transmembrane transporter activity
HBM81_16365	COG1136	(ABC) transporter
HBM81_16370	COG1538	Outer membrane efflux protein
HBM81_16385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HBM81_16390	COG1162	GTPase activity
HBM81_16400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBM81_16420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBM81_16425	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_16470	COG2986	histidine ammonia-lyase
HBM81_16485	COG0318	PFAM AMP-dependent synthetase and ligase
HBM81_16495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBM81_16540	COG1426	Protein conserved in bacteria
HBM81_16575	COG0793	Belongs to the peptidase S41A family
HBM81_16590	COG2267	carboxylic ester hydrolase activity
HBM81_16600	COG1012	belongs to the aldehyde dehydrogenase family
HBM81_16605	COG3265	gluconokinase activity
HBM81_16615	COG0800	Aldolase
HBM81_16630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBM81_16635	COG0280	phosphate acetyltransferase
HBM81_16635	COG0857	belongs to the CobB CobQ family
HBM81_16640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBM81_16640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBM81_16660	COG0740	serine-type endopeptidase activity
HBM81_16680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBM81_16690	COG2813	Specifically methylates the guanine in position
HBM81_16690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBM81_16790	COG0788	formyltetrahydrofolate deformylase activity
HBM81_16815	COG4651	solute:proton antiporter activity
HBM81_16815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM81_16835	COG0724	RNA recognition motif
HBM81_16840	COG0210	DNA helicase
HBM81_16865	COG1733	regulation of RNA biosynthetic process
HBM81_16875	COG2900	Belongs to the SlyX family
HBM81_16885	COG1280	lysine exporter protein (LysE YggA)
HBM81_16890	COG1560	Kdo2-lipid A biosynthetic process
HBM81_16900	COG1301	dicarboxylic acid transport
HBM81_16955	COG0473	3-isopropylmalate dehydrogenase activity
HBM81_17020	COG0583	DNA-binding transcription factor activity
HBM81_17030	COG0625	glutathione transferase activity
HBM81_17035	COG2378	regulation of single-species biofilm formation
HBM81_17040	COG0546	phosphoglycolate phosphatase activity
HBM81_17055	COG1530	ribonuclease E activity
HBM81_17060	COG0318	PFAM AMP-dependent synthetase and ligase
HBM81_17075	COG0583	DNA-binding transcription factor activity
HBM81_17080	COG4221	oxidoreductase activity
HBM81_17085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBM81_17095	COG0534	Mate efflux family protein
HBM81_17110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HBM81_17150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HBM81_17155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBM81_17170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBM81_17180	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HBM81_17180	COG0644	oxidoreductase
HBM81_17185	COG0425	Belongs to the sulfur carrier protein TusA family
HBM81_17190	COG4535	Mg2 and Co2 transporter CorC
HBM81_17200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBM81_17220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBM81_17225	COG0475	glutathione-regulated potassium exporter activity
HBM81_17225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBM81_17230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBM81_17240	COG0484	heat shock protein binding
HBM81_17245	COG0789	Transcriptional regulator
HBM81_17250	COG0598	Magnesium transport protein CorA
HBM81_17270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBM81_17275	COG1074	ATP-dependent DNA helicase activity
HBM81_17280	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBM81_17300	COG2226	methyltransferase
HBM81_17315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBM81_17320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBM81_17335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBM81_17335	COG2111	Na H antiporter
HBM81_17340	COG1006	Multisubunit Na H antiporter MnhC subunit
HBM81_17345	COG0651	ATP synthesis coupled electron transport
HBM81_17355	COG2212	antiporter activity
HBM81_17375	COG0195	Participates in both transcription termination and antitermination
HBM81_17425	COG0237	dephospho-CoA kinase activity
HBM81_17435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBM81_17450	COG0497	DNA recombination
HBM81_17460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBM81_17490	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBM81_17490	COG2169	Transcriptional regulator
HBM81_17495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBM81_17560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBM81_17575	COG0326	Molecular chaperone. Has ATPase activity
HBM81_17590	COG2056	Na+-H+ antiporter family
HBM81_17595	COG0596	Alpha beta hydrolase
HBM81_17690	COG0546	phosphoglycolate phosphatase activity
HBM81_17695	COG1716	ATPase activity
HBM81_17740	COG0181	hydroxymethylbilane synthase activity
HBM81_17750	COG3275	phosphorelay sensor kinase activity
HBM81_17770	COG1538	Outer membrane efflux protein
HBM81_17775	COG0697	spore germination
HBM81_17800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBM81_17805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBM81_17810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBM81_17815	COG0772	Belongs to the SEDS family
HBM81_17840	COG4974	Belongs to the 'phage' integrase family
HBM81_17845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM81_17855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBM81_17865	COG2197	response regulator
HBM81_17880	COG0793	Belongs to the peptidase S41A family
HBM81_17885	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBM81_17890	COG0795	lipopolysaccharide-transporting ATPase activity
HBM81_17930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBM81_17930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBM81_17940	COG0004	ammonium transporteR
HBM81_17945	COG0347	Belongs to the P(II) protein family
HBM81_17955	COG0606	chelatase, subunit chli
HBM81_18030	COG1061	Type III restriction enzyme res subunit
HBM81_18045	COG0659	secondary active sulfate transmembrane transporter activity
HBM81_18050	COG0589	response to stress
HBM81_18080	COG0606	chelatase, subunit chli
HBM81_18095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBM81_18110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBM81_18125	COG0318	PFAM AMP-dependent synthetase and ligase
HBM81_18135	COG0477	Major facilitator Superfamily
HBM81_18140	COG2860	membrane
HBM81_18150	COG1253	flavin adenine dinucleotide binding
HBM81_18170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBM81_18205	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBM81_18215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBM81_18250	COG1309	transcriptional regulator
HBM81_18285	COG0758	DNA mediated transformation
HBM81_18295	COG0697	spore germination
HBM81_18300	COG1309	transcriptional regulator
HBM81_18315	COG0386	Belongs to the glutathione peroxidase family
HBM81_18380	COG1121	(ABC) transporter
HBM81_18385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBM81_18390	COG1280	lysine exporter protein (LysE YggA)
HBM81_18395	COG2837	iron assimilation
HBM81_18405	COG0281	malic enzyme
HBM81_18450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBM81_18450	COG0519	Catalyzes the synthesis of GMP from XMP
HBM81_18455	COG4399	Belongs to the UPF0754 family
HBM81_18460	COG2259	Doxx family
HBM81_18465	COG0586	Pfam SNARE associated Golgi protein
HBM81_18480	COG1192	Involved in chromosome partitioning
HBM81_18490	COG0271	Belongs to the BolA IbaG family
HBM81_18525	COG3756	Protein conserved in bacteria
HBM81_18620	COG0642	Histidine kinase
HBM81_18625	COG0745	RESPONSE REGULATOR receiver
HBM81_18630	COG2194	sulfuric ester hydrolase activity
HBM81_18635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBM81_18640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBM81_18655	COG1570	exodeoxyribonuclease VII activity
HBM81_18680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBM81_18685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBM81_18695	COG0659	secondary active sulfate transmembrane transporter activity
HBM81_18715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBM81_18750	COG2826	transposase and inactivated derivatives, IS30 family
HBM81_18780	COG1324	tolerance protein
HBM81_18785	COG0673	inositol 2-dehydrogenase activity
HBM81_18805	COG2826	transposase and inactivated derivatives, IS30 family
HBM81_18860	COG2267	carboxylic ester hydrolase activity
HBM81_18880	COG3321	synthase
HBM81_18880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBM81_18880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBM81_18880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBM81_18885	COG1960	acyl-CoA dehydrogenase activity
HBM81_18895	COG2197	response regulator
HBM81_18905	COG3916	Acyl-homoserine-lactone synthase
HBM81_18910	COG0477	Major facilitator Superfamily
HBM81_18915	COG1024	Enoyl-CoA hydratase
HBM81_18920	COG1024	Enoyl-CoA hydratase
HBM81_18925	COG1960	acyl-CoA dehydrogenase activity
HBM81_18930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBM81_18950	COG1113	amino acid transport
HBM81_18955	COG1113	amino acid transport
HBM81_18960	COG0251	oxidation-reduction process
HBM81_19000	COG0564	pseudouridine synthase activity
HBM81_19060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBM81_19075	COG1802	Transcriptional regulator
HBM81_19085	COG1448	Aminotransferase
HBM81_19090	COG0277	FAD linked oxidase domain protein
HBM81_19100	COG2186	Transcriptional regulator
HBM81_19110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBM81_19115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBM81_19130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBM81_19135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBM81_19140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBM81_19155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBM81_19195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBM81_19200	COG1596	polysaccharide export
HBM81_19225	COG0728	peptidoglycan biosynthetic process
HBM81_19230	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBM81_19285	COG0546	phosphoglycolate phosphatase activity
HBM81_19290	COG1028	Short-chain dehydrogenase reductase Sdr
HBM81_19310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM81_19315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBM81_19320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBM81_19325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBM81_19330	COG1116	anion transmembrane transporter activity
HBM81_19335	COG1309	transcriptional regulator
HBM81_19340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBM81_19350	COG0196	riboflavin kinase activity
HBM81_19355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBM81_19365	COG1047	Peptidyl-prolyl cis-trans
HBM81_19405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBM81_19460	COG2951	lytic endotransglycosylase activity
HBM81_19465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBM81_19480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBM81_19490	COG0671	phosphoesterase, PA-phosphatase related
HBM81_19495	COG0861	Integral membrane protein TerC family
HBM81_19505	COG0754	glutathionylspermidine amidase activity
HBM81_19515	COG0402	S-adenosylhomocysteine deaminase activity
HBM81_19530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBM81_19535	COG1230	cation diffusion facilitator family transporter
HBM81_19550	COG0706	membrane insertase activity