locus-tag class description FDB76_00090 ENOG4105DR5 peptidase FDB76_00180 ENOG4105CBP Major Facilitator FDB76_00185 ENOG4105EGI Transcriptional regulator FDB76_00190 ENOG4108ETY sodium dicarboxylate symporter FDB76_00195 ENOG4105JAB phenazine biosynthesis protein, phzf family FDB76_00225 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) FDB76_00240 ENOG4105D3G Pseudouridine synthase FDB76_00245 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) FDB76_00260 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDB76_00285 ENOG4108JPW Aminotransferase FDB76_00290 ENOG4105DY8 decarboxylase FDB76_00300 ENOG4105F7P transcriptional regulator AsnC family FDB76_00305 ENOG4107RA9 decarboxylase FDB76_00315 ENOG4105CVA phosphate FDB76_00320 ENOG4105C8U phosphate abc transporter FDB76_00330 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FDB76_00335 ENOG4105ERU peptidase FDB76_00345 ENOG4105D5G Transposase FDB76_00355 ENOG4107QTF adenylosuccinate lyase FDB76_00375 ENOG4108Z0R Transferase FDB76_00380 ENOG4105DZ1 carboxypeptidase FDB76_00400 ENOG4108K5P (LipO)protein FDB76_00405 ENOG4105EJC lysr family transcriptional regulator FDB76_00410 ENOG4105DAN ATP-dependent protease FDB76_00425 ENOG4105DHU Bile acid FDB76_00445 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FDB76_00455 ENOG4105D22 carbon starvation protein FDB76_00460 ENOG4105VCD cytoplasmic protein FDB76_00495 ENOG4108K8K Transcriptional regulator FDB76_00510 ENOG4105C26 Dehydrogenase FDB76_00515 ENOG4105C85 amino acid FDB76_00520 ENOG4105ETT transcriptional Regulator, LysR family FDB76_00525 ENOG4105C94 Transporter FDB76_00530 ENOG4105C94 Transporter FDB76_00540 ENOG4105C26 Dehydrogenase FDB76_00545 ENOG4107QZF nitrite reductase NADPH large subunit FDB76_00550 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) FDB76_00590 ENOG41060M8 Pfam:PhdYeFM FDB76_00595 ENOG4107QNK )-transporter FDB76_00600 ENOG4107WEA mandelate racemase muconate lactonizing FDB76_00610 ENOG4105J7D transcriptional regulator FDB76_00630 ENOG4105C2I pirin domain protein FDB76_00640 ENOG4105WWK YheO domain protein FDB76_00655 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_00670 ENOG4108IPW abc transporter atp-binding protein FDB76_00690 ENOG4105C0W non-ribosomal peptide synthetase FDB76_00695 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FDB76_00700 ENOG4105WQI isochorismatase FDB76_00715 ENOG4105BZ1 (ABC) transporter FDB76_00735 ENOG4105E4F Isochorismate synthase FDB76_00750 ENOG4105NX3 Membrane FDB76_00785 ENOG4105EUJ GTP cyclohydrolase i FDB76_00795 ENOG4105C7W Xanthine dehydrogenase FDB76_00830 ENOG4105DDQ anthranilate synthase FDB76_00840 ENOG4105DUX Transporter FDB76_00845 ENOG4105C5F glutamine synthetase FDB76_00855 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) FDB76_00890 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDB76_00895 ENOG4107QNR UPF0135 protein FDB76_00900 ENOG4105C0H protease FDB76_00910 ENOG4105C6K Malic enzyme FDB76_00915 ENOG4105BZU Histidine kinase FDB76_00920 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FDB76_00925 ENOG4105SYT Methylenetetrahydrofolate reductase FDB76_00930 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) FDB76_00945 ENOG4107QPN acyl-Coa dehydrogenase FDB76_00950 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FDB76_00955 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FDB76_00965 ENOG4107RNU major facilitator superfamily MFS_1 FDB76_00975 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FDB76_00980 ENOG4105CE9 30S ribosomal protein S2 FDB76_01020 ENOG4105CVE Lytic murein transglycosylase FDB76_01025 ENOG4105CNI cell division protein FtsW FDB76_01040 ENOG4105E3A (ABC) transporter FDB76_01045 ENOG4105DA5 (ABC) transporter FDB76_01080 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDB76_01090 ENOG4105ENT Efflux transporter rnd family, mfp subunit FDB76_01100 ENOG4105E89 ABC transporter FDB76_01105 ENOG4105DSP amino acid AbC transporter FDB76_01110 ENOG4106YG3 ABC transporter FDB76_01115 ENOG4108JEH abc transporter atp-binding protein FDB76_01125 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FDB76_01130 ENOG4105CFP Peptidase U32 FDB76_01135 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDB76_01140 ENOG4105JAB phenazine biosynthesis protein, phzf family FDB76_01145 ENOG4105DP0 ferredoxin-NADP reductase FDB76_01150 ENOG4108R96 Methyltransferase, YaeB family FDB76_01160 ENOG4107QHF type ii secretion system protein e FDB76_01170 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDB76_01175 ENOG4105DHQ Histidine kinase FDB76_01185 ENOG4105M6F mutator MutT protein FDB76_01195 ENOG4105BZ4 penicillin-binding protein FDB76_01200 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FDB76_01205 ENOG4105VUT cytoplasmic protein FDB76_01210 ENOG4107QYG anthranilate phosphoribosyltransferase FDB76_01220 ENOG4105CK2 sodium dicarboxylate symporter FDB76_01225 ENOG4105C1G acyl-Coa dehydrogenase FDB76_01230 ENOG4105NIV Esterase FDB76_01235 ENOG4105CQC Prephenate dehydratase FDB76_01240 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase FDB76_01250 ENOG4105CIN aminoacyl-histidine dipeptidase FDB76_01255 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FDB76_01285 ENOG4105M08 Membrane FDB76_01290 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDB76_01300 ENOG4105VEQ Cold shock protein FDB76_01305 ENOG4105C1J atp-dependent rna helicase FDB76_01315 ENOG41069NU Nitroreductase FDB76_01350 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase FDB76_01365 ENOG4105C5I Dehydrogenase FDB76_01370 ENOG4105ERG peptidase m48, ste24p FDB76_01375 ENOG4105KTH gatB Yqey FDB76_01380 ENOG4105VCC 30S ribosomal protein S21 FDB76_01405 ENOG4105D9P serine threonine protein kinase FDB76_01430 ENOG4105EVZ LysR family transcriptional regulator FDB76_01435 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FDB76_01440 ENOG4105C26 Dehydrogenase FDB76_01475 ENOG4105H4F exported protein FDB76_01505 ENOG4105D6U Sodium Glutamate Symporter FDB76_01515 ENOG4105JXH GntR family transcriptional regulator FDB76_01565 ENOG4105CSH Transporter FDB76_01590 ENOG4105CEB Aspartate aminotransferase FDB76_01605 ENOG4105F1S paraquat-inducible protein a FDB76_01610 ENOG4105DY2 Paraquat-inducible protein b FDB76_01635 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FDB76_01710 ENOG4105CK2 sodium dicarboxylate symporter FDB76_01725 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FDB76_01730 ENOG4108UMI ABC transporter, permease FDB76_01735 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FDB76_01745 ENOG4105C12 Phosphoribosylglycinamide synthetase FDB76_01750 ENOG4105DC1 bifunctional purine biosynthesis protein purh FDB76_01755 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) FDB76_01805 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FDB76_01810 ENOG4105CDU Replicative dna helicase FDB76_01835 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) FDB76_01840 ENOG4105CCU oxidase (Subunit III) FDB76_01845 ENOG4105BZ9 Cytochrome C oxidase, subunit I FDB76_01850 ENOG4105E2S oxidase) subunit II FDB76_01875 ENOG4107BJW polysaccharide deacetylase FDB76_01880 ENOG4105CND Glycosyl transferase, family 2 FDB76_01885 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD FDB76_01895 ENOG4105DEN Luciferase family FDB76_01915 ENOG4105CC0 LysR family Transcriptional regulator FDB76_01930 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FDB76_01935 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDB76_01940 ENOG4105GVF (ABC) transporter FDB76_01955 ENOG4105C1G acyl-Coa dehydrogenase FDB76_01965 ENOG4108MEJ flavin reductase domain protein FDB76_01970 ENOG4105D06 uba thif-type nad fad binding protein FDB76_01990 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FDB76_01995 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) FDB76_02005 ENOG4105C08 Histidine kinase FDB76_02010 ENOG4105EEX Two component transcriptional regulator (Winged helix family FDB76_02015 ENOG4105CFQ glutamine synthetase FDB76_02030 ENOG4107S74 Lysophospholipid transporter LplT FDB76_02035 ENOG4105CFU surface antigen FDB76_02055 ENOG4107QIJ Aconitate hydratase 2 FDB76_02065 ENOG4105EYW Ion transport protein FDB76_02070 ENOG4105F27 Major Facilitator FDB76_02085 ENOG4105DZ2 Transcriptional regulator FDB76_02120 ENOG4105K8N protein family UPF0079, ATPase FDB76_02125 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) FDB76_02135 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FDB76_02140 ENOG4108TZV Membrane FDB76_02145 ENOG4108RCM Nitroreductase FDB76_02155 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) FDB76_02170 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FDB76_02175 ENOG4107FQ9 ethanolamine ammonia-lyase FDB76_02180 ENOG4105CPD ethanolamine ammonia-lyase FDB76_02185 ENOG4107R55 ethanolamine transporter FDB76_02195 ENOG4107RR1 TRANSCRIPTIONal FDB76_02205 ENOG4105C0A alcohol dehydrogenase FDB76_02210 ENOG4107QUV Domain protein FDB76_02220 ENOG4105F4I Transcriptional regulator FDB76_02240 ENOG4105CD8 aminopeptidase N FDB76_02270 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) FDB76_02275 ENOG4105EW9 transcriptional regulator AsnC family FDB76_02290 ENOG4105R8C Transcriptional regulator FDB76_02300 ENOG4105CUY Mechanosensitive ion channel FDB76_02335 ENOG4105CNM Receptor FDB76_02355 ENOG4105C5H ABC transporter FDB76_02360 ENOG41081QV Universal stress protein FDB76_02375 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FDB76_02385 ENOG4105DKK Benzoate FDB76_02390 ENOG4105EW9 transcriptional regulator AsnC family FDB76_02395 ENOG4108NIW Leucine export protein LeuE FDB76_02400 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FDB76_02405 ENOG4105C5Q Transcriptional regulator FDB76_02415 ENOG4105CHU acetyl-coa acetyltransferase FDB76_02420 ENOG4105CHR reductase FDB76_02445 ENOG4107QMP dna polymerase iii subunits gamma and tau FDB76_02450 ENOG4105HSS phospholipase C FDB76_02460 ENOG4105C0A alcohol dehydrogenase FDB76_02490 ENOG4105CBC glutamate synthase FDB76_02510 ENOG4105D8G Major Facilitator superfamily FDB76_02520 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FDB76_02525 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein FDB76_02545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDB76_02555 ENOG4107QZF nitrite reductase NADPH large subunit FDB76_02560 ENOG4108IFG nitrite reductase, (NAD(P)H) FDB76_02580 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FDB76_02595 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FDB76_02600 ENOG4105CVM Molybdenum cofactor synthesis domain protein FDB76_02610 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDB76_02635 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) FDB76_02640 ENOG4105CMR udp-glucose 4-epimerase FDB76_02700 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDB76_02705 ENOG4105CUX Signal transduction histidine kinase FDB76_02730 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FDB76_02735 ENOG4105KNE Phosphatidate cytidylyltransferase FDB76_02770 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FDB76_02785 ENOG4105Y3E Modulates RecA activity (By similarity) FDB76_02795 ENOG4105VEJ Heat shock protein FDB76_02800 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 FDB76_02825 ENOG4105F7P transcriptional regulator AsnC family FDB76_02835 ENOG4105C85 amino acid FDB76_02850 ENOG4105CHH sulfate transporter FDB76_02855 ENOG4108RAV Conserved protein FDB76_02860 ENOG4105D8V Glucose sorbosone dehydrogenase FDB76_02870 ENOG4105BZU Histidine kinase FDB76_02890 ENOG4105DM4 PTS System FDB76_02895 ENOG4105DE4 1-phosphofructokinase FDB76_02900 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FDB76_02925 ENOG4105CWM branched-chain amino acid transport system II carrier protein FDB76_02930 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FDB76_02935 ENOG4105CC0 LysR family Transcriptional regulator FDB76_02945 ENOG4105M2J Glutaredoxin FDB76_02950 ENOG4105C8Y Acetylornithine aminotransferase FDB76_02955 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FDB76_02980 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FDB76_02990 ENOG41068P6 UPF0319 protein FDB76_03010 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDB76_03015 ENOG4105C4M (Ubiquinol oxidase) subunit I FDB76_03035 ENOG4105PV3 Inner membrane protein yqiJ FDB76_03050 ENOG4105E0K tonB-dependent siderophore receptor FDB76_03060 ENOG4105HDD phospholipase FDB76_03065 ENOG4105CZN Potassium uptake protein FDB76_03075 ENOG4105C7B Threonine dehydratase FDB76_03105 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) FDB76_03110 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDB76_03120 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDB76_03135 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDB76_03180 ENOG4107VMU Membrane FDB76_03185 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) FDB76_03195 ENOG4107QP7 CoA-transferase subunit A FDB76_03200 ENOG4107QNJ CoA-transferase subunit B FDB76_03205 ENOG4105CHU acetyl-coa acetyltransferase FDB76_03210 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase FDB76_03215 ENOG4105F2Z 3-oxoadipate enol-lactonase FDB76_03220 ENOG4105D2S major facilitator superfamily FDB76_03225 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FDB76_03230 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta FDB76_03235 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha FDB76_03240 ENOG4105FF2 Type I DHQase FDB76_03245 ENOG4106JPM 3-dehydroshikimate dehydratase FDB76_03250 ENOG4105TW1 Carbohydrate-selective porin OprB FDB76_03255 ENOG4105DZG Dehydrogenase FDB76_03265 ENOG4105MD1 YeeE YedE family protein FDB76_03280 ENOG4107HP6 Transcriptional regulator FDB76_03285 ENOG4108PTX LysR family Transcriptional regulator FDB76_03290 ENOG4105C1G acyl-Coa dehydrogenase FDB76_03315 ENOG4105DNH Major Facilitator FDB76_03325 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FDB76_03345 ENOG4105FUY alpha subunit FDB76_03355 ENOG4105CHR reductase FDB76_03395 ENOG4105C26 Dehydrogenase FDB76_03405 ENOG4105F2Z 3-oxoadipate enol-lactonase FDB76_03410 ENOG4105CHU acetyl-coa acetyltransferase FDB76_03415 ENOG4107QNJ CoA-transferase subunit B FDB76_03420 ENOG4107QP7 CoA-transferase subunit A FDB76_03430 ENOG4105NN7 muconolactone delta-isomerase FDB76_03435 ENOG4105DTQ mandelate racemase muconate lactonizing FDB76_03440 ENOG4108KB2 LysR family Transcriptional regulator FDB76_03450 ENOG4107EJG GntR family transcriptional regulator FDB76_03470 ENOG4105CZJ Aldehyde dehydrogenase FDB76_03490 ENOG4105C1G acyl-Coa dehydrogenase FDB76_03495 ENOG4105CHR reductase FDB76_03500 ENOG4108JU7 Transcriptional regulator FDB76_03510 ENOG41062QD Membrane FDB76_03525 ENOG4107RGH Aldehyde dehydrogenase FDB76_03540 ENOG4105CH6 catalase FDB76_03565 ENOG4105K56 Transcriptional regulator FDB76_03570 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDB76_03580 ENOG4105NAE bifunctional deaminase-reductase domain protein FDB76_03610 ENOG4107Z3H Transcriptional regulator, TetR family FDB76_03620 ENOG4105CHJ isochorismatase hydrolase FDB76_03630 ENOG4105D8V Glucose sorbosone dehydrogenase FDB76_03635 ENOG4105CKD glutathione-regulated potassium-efflux system protein FDB76_03645 ENOG4105CH2 amidohydrolase FDB76_03660 ENOG4105D5K Hemolysin activator protein FDB76_03665 ENOG4105CKT filamentous hemagglutinin FDB76_03695 ENOG4105FDP GntR family transcriptional regulator FDB76_03710 ENOG4106KR7 LysR family Transcriptional regulator FDB76_03735 ENOG4108JQ1 Dehydrogenase FDB76_03740 ENOG4105JSC dimethylmenaquinone methyltransferase FDB76_03760 ENOG4105CW7 secretion protein, HlyD family FDB76_03775 ENOG4105CZJ Aldehyde dehydrogenase FDB76_03780 ENOG4105C01 Dihydroxy-acid dehydratase FDB76_03790 ENOG4105DDW LysR family Transcriptional regulator FDB76_03805 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDB76_03810 ENOG4105CF7 AraC family transcriptional regulator FDB76_03825 ENOG4105DQ4 alcohol dehydrogenase FDB76_03835 ENOG4105EHG Permease protein FDB76_03840 ENOG4105E0A ABC, transporter FDB76_03860 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FDB76_03945 ENOG4108UAJ Transcriptional regulator FDB76_03985 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) FDB76_04040 ENOG4108BAS reductase FDB76_04055 ENOG4108R6W Transcriptional regulator, ARAC family FDB76_04060 ENOG4108821 RND type efflux pump FDB76_04065 ENOG4105E0F Histidine kinase FDB76_04070 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDB76_04075 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDB76_04085 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDB76_04095 ENOG4105CT3 Monooxygenase FDB76_04115 ENOG4105CJP fad dependent oxidoreductase FDB76_04135 ENOG4105X0I Fimbrial FDB76_04190 ENOG4107RZC phospholipase d FDB76_04210 ENOG4108IGT Dipeptidase FDB76_04255 ENOG4105WQI isochorismatase FDB76_04260 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FDB76_04265 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) FDB76_04275 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FDB76_04280 ENOG4105F4R Transcriptional regulator mode FDB76_04285 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit FDB76_04290 ENOG4108YS2 small subunit FDB76_04295 ENOG4105F57 Anthranilate dioxygenase reductase FDB76_04320 ENOG4105CHR reductase FDB76_04335 ENOG4105CF7 AraC family transcriptional regulator FDB76_04345 ENOG4105DTD Dehydrogenase FDB76_04350 ENOG4105CY2 Citrate transporter FDB76_04360 ENOG4108M0I Transcriptional regulator FDB76_04370 ENOG4107QNJ CoA-transferase subunit B FDB76_04375 ENOG4105CRW Short chain fatty acid transporter FDB76_04380 ENOG4105CHU acetyl-coa acetyltransferase FDB76_04390 ENOG4107YNJ LysR family Transcriptional regulator FDB76_04405 ENOG4108IJ0 Aspartate ammonia-lyase FDB76_04415 ENOG4105CSH Transporter FDB76_04435 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDB76_04440 ENOG4106FTQ Taurine ABC transporter, periplasmic FDB76_04455 ENOG4105FDP GntR family transcriptional regulator FDB76_04465 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FDB76_04470 ENOG4105KVH Transcriptional regulator FDB76_04475 ENOG4105UEI Transcriptional Regulator AraC Family FDB76_04490 ENOG4108VCT Sulfite exporter TauE/SafE FDB76_04500 ENOG4107QPB Beta-lactamase domain protein FDB76_04510 ENOG4105FFC UPF0187 protein FDB76_04520 ENOG4105CHR reductase FDB76_04535 ENOG4105CPP Dehydrogenase, E1 component FDB76_04540 ENOG4107R0V Pyruvate dehydrogenase FDB76_04545 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) FDB76_04560 ENOG4105BZU Histidine kinase FDB76_04570 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) FDB76_04575 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FDB76_04620 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) FDB76_04635 ENOG4105C28 cystathionine FDB76_04645 ENOG4105F2W methyltransferase FDB76_04680 ENOG4105K59 histidine triad (HIT) protein FDB76_04705 ENOG4107QWP ABC-2 type transporter FDB76_04710 ENOG4107QWP ABC-2 type transporter FDB76_04730 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) FDB76_04735 ENOG4105CNM Receptor FDB76_04755 ENOG4107TSN permease FDB76_04760 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) FDB76_04780 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) FDB76_04785 ENOG4108YZT Adenosylcobinamide kinase FDB76_04840 ENOG4105DJU Siderophore biosynthesis protein FDB76_04845 ENOG4105DUU IucA IucC family protein FDB76_04865 ENOG4108Z66 YbaK ebsC protein FDB76_04880 ENOG4105C1G acyl-Coa dehydrogenase FDB76_04885 ENOG4105C1G acyl-Coa dehydrogenase FDB76_04890 ENOG4105EEF Alkane 1-monooxygenase FDB76_04895 ENOG4105E7U AraC family transcriptional regulator FDB76_04900 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FDB76_04905 ENOG4105K70 DNA-binding protein FDB76_04920 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family FDB76_04930 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins FDB76_04935 ENOG4108Z4V iron-sulfur cluster assembly FDB76_04950 ENOG4108ZIT Ferredoxin, 2FE-2S FDB76_04955 ENOG4105F8J Adenylate Guanylate cyclase FDB76_04965 ENOG4108JA2 transcriptioN-repair coupling factor FDB76_04985 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) FDB76_04990 ENOG4105K4T epimerase FDB76_05005 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase FDB76_05025 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FDB76_05035 ENOG4105DGW oligopeptidase A FDB76_05075 ENOG4105SG9 biopolymer transport protein, ExbD FDB76_05085 ENOG4107QP3 malate synthase g FDB76_05090 ENOG4105D6Z AFG1 family ATPase FDB76_05100 ENOG4107RN6 Monooxygenase FDB76_05120 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) FDB76_05125 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) FDB76_05140 ENOG4108Z6B deaminase FDB76_05160 ENOG4108RTD type II secretion system protein K FDB76_05185 ENOG4105F8V Hydrolase, tatD family FDB76_05195 ENOG4107QRG dna polymerase iii FDB76_05205 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) FDB76_05210 ENOG4105BZ1 (ABC) transporter FDB76_05225 ENOG4105FA0 parb-like partition protein FDB76_05230 ENOG4107QJE Chromosome Partitioning Protein FDB76_05240 ENOG4108S0S Nucleotidyl transferase FDB76_05245 ENOG4105EHM Aminoglycoside phosphotransferase FDB76_05250 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) FDB76_05255 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) FDB76_05260 ENOG4105D2N Aldolase FDB76_05280 ENOG4108UHJ MAF-like protein FDB76_05285 ENOG4105EZE Cupin 4 family protein FDB76_05295 ENOG41080HT Transcriptional regulator, arsr family FDB76_05310 ENOG4105XPP Protein of unknown function (DUF1275) FDB76_05315 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme FDB76_05320 ENOG4105BZ1 (ABC) transporter FDB76_05330 ENOG4108ZX5 transcriptional regulator FDB76_05340 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FDB76_05345 ENOG4105CK7 Sodium proline symporter FDB76_05350 ENOG4105EW9 transcriptional regulator AsnC family FDB76_05355 ENOG4105C26 Dehydrogenase FDB76_05360 ENOG4105YGK Pfam:UPF0157 FDB76_05375 ENOG4108T58 Mg2 transport protein CorA FDB76_05385 ENOG4108YYC ycei family FDB76_05395 ENOG4105CV1 Transketolase (EC 2.2.1.1) FDB76_05420 ENOG4108HWY Beta-lactamase FDB76_05440 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) FDB76_05445 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FDB76_05465 ENOG4105X0I Fimbrial FDB76_05470 ENOG4105GQR Chaperone FDB76_05500 ENOG4108IPJ Membrane FDB76_05510 ENOG4105ETS cytosine purines uracil thiamine allantoin FDB76_05520 ENOG4105CC0 LysR family Transcriptional regulator FDB76_05540 ENOG41067SE Tetr family transcriptional regulator FDB76_05555 ENOG4105EW9 transcriptional regulator AsnC family FDB76_05565 ENOG4105CDA abc transporter atp-binding protein FDB76_05570 ENOG4105DRP amino acid AbC transporter FDB76_05575 ENOG4105EAD ABC transporter FDB76_05590 ENOG4107T8P acyl-Coa dehydrogenase FDB76_05605 ENOG4105D01 (LipO)protein FDB76_05610 ENOG4105D01 (LipO)protein FDB76_05615 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FDB76_05620 ENOG4108UMI ABC transporter, permease FDB76_05625 ENOG4105C3G gtp-binding protein FDB76_05650 ENOG4108UMN azlc family FDB76_05655 ENOG4105ZED uncharacterized protein ygaH FDB76_05685 ENOG4105E7U AraC family transcriptional regulator FDB76_05690 ENOG4108V06 Glutathione peroxidase FDB76_05700 ENOG4105CHM Aminotransferase FDB76_05715 ENOG4105C0B DNA polymerase III (alpha subunit) FDB76_05740 ENOG4108JU3 Alkyl hydroperoxide reductase FDB76_05755 ENOG4108KB2 LysR family Transcriptional regulator FDB76_05760 ENOG4105D6J arsenicaL-resistance protein FDB76_05765 ENOG41082YX Transcriptional regulator, arsr family FDB76_05780 ENOG4105CPN adenine deaminase FDB76_05790 ENOG4105CBN LysR family transcriptional regulator FDB76_05800 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease FDB76_05810 ENOG4105E2B Taurine dioxygenase FDB76_05815 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FDB76_05820 ENOG4108IY8 ABC, transporter FDB76_05825 ENOG4106FTQ Taurine ABC transporter, periplasmic FDB76_05835 ENOG4105C54 Major Facilitator superfamily FDB76_05860 ENOG4105C4M (Ubiquinol oxidase) subunit I FDB76_05865 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FDB76_05875 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FDB76_05880 ENOG4108K70 Transcriptional regulator FDB76_05895 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FDB76_05900 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase FDB76_05915 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) FDB76_05920 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase FDB76_05930 ENOG4105DXI Major Facilitator superfamily FDB76_05950 ENOG41067MG lrgb family FDB76_05955 ENOG4105VAW lrga family FDB76_05960 ENOG4105CMU LysR family (Transcriptional regulator FDB76_05965 ENOG4108SHQ Glutathione S-transferase FDB76_05970 ENOG4105CYM Glutathione S-transferase FDB76_05975 ENOG4105CBN LysR family transcriptional regulator FDB76_05980 ENOG4105CHR reductase FDB76_05990 ENOG4105D7W serine acetyltransferase FDB76_05995 ENOG4105ESN nucleotide-binding protein FDB76_06000 ENOG4105C9B Cysteine desulfurase FDB76_06015 ENOG4105EXG Transcriptional regulator FDB76_06025 ENOG4105CT1 (ABC) transporter FDB76_06030 ENOG4107RP9 extracellular solute-binding protein, family 3 FDB76_06035 ENOG4105CDA abc transporter atp-binding protein FDB76_06040 ENOG4108HW4 amino acid AbC transporter FDB76_06045 ENOG4105EAD ABC transporter FDB76_06060 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FDB76_06065 ENOG4105BZU Histidine kinase FDB76_06075 ENOG4105EW9 transcriptional regulator AsnC family FDB76_06085 ENOG4105KT5 UmuD protein FDB76_06110 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FDB76_06155 ENOG4105HEI LysR family (Transcriptional regulator FDB76_06175 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_06180 ENOG4105R8C Transcriptional regulator FDB76_06185 ENOG4105C1G acyl-Coa dehydrogenase FDB76_06190 ENOG4107QX3 carboxylase FDB76_06195 ENOG4105E39 Enoyl-CoA hydratase FDB76_06210 ENOG4105CC0 LysR family Transcriptional regulator FDB76_06225 ENOG4105CSU acyl-Coa dehydrogenase FDB76_06235 ENOG4105EQ0 Major Facilitator superfamily FDB76_06245 ENOG4107QNJ CoA-transferase subunit B FDB76_06250 ENOG4107QP7 CoA-transferase subunit A FDB76_06255 ENOG4107RGD Major Facilitator superfamily FDB76_06260 ENOG4105C1G acyl-Coa dehydrogenase FDB76_06265 ENOG4105E39 Enoyl-CoA hydratase FDB76_06270 ENOG4105CHR reductase FDB76_06275 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FDB76_06280 ENOG4105CHU acetyl-coa acetyltransferase FDB76_06290 ENOG4105EQ0 Major Facilitator superfamily FDB76_06295 ENOG4105EA8 2-Nitropropane dioxygenase FDB76_06300 ENOG4108UKI Enoyl-CoA hydratase FDB76_06315 ENOG4105C1G acyl-Coa dehydrogenase FDB76_06320 ENOG4107RGD Major Facilitator superfamily FDB76_06325 ENOG4108KAZ Involved in phosphonate degradation (By similarity) FDB76_06330 ENOG4107STF Involved in phosphonate degradation (By similarity) FDB76_06340 ENOG4107RCV ABC transporter, permease FDB76_06345 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FDB76_06350 ENOG4105C4Y ABC transporter FDB76_06360 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase FDB76_06365 ENOG4107HP6 Transcriptional regulator FDB76_06375 ENOG4105HEI LysR family (Transcriptional regulator FDB76_06380 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase FDB76_06385 ENOG4105C26 Dehydrogenase FDB76_06395 ENOG4105ETS cytosine purines uracil thiamine allantoin FDB76_06405 ENOG4105C26 Dehydrogenase FDB76_06410 ENOG4108M8W Monooxygenase FDB76_06415 ENOG4105MXW flavin reductase domain protein, FMN-binding FDB76_06420 ENOG4108MXF Alpha Beta Hydrolase FDB76_06440 ENOG4105CPW cytochrome b561 FDB76_06445 ENOG4107VGR Catalase FDB76_06485 ENOG4107YAU phenylacetic acid degradation protein FDB76_06495 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein FDB76_06500 ENOG4105DZS Phenylacetate-CoA ligase FDB76_06505 ENOG4105CHU acetyl-coa acetyltransferase FDB76_06510 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FDB76_06515 ENOG4108UKI Enoyl-CoA hydratase FDB76_06520 ENOG4105E39 Enoyl-CoA hydratase FDB76_06525 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FDB76_06530 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit FDB76_06535 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit FDB76_06540 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit FDB76_06545 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit FDB76_06550 ENOG4105DXM phenylacetic acid degradation protein FDB76_06555 ENOG4105EJQ L-serine dehydratase FDB76_06560 ENOG4107QTZ amino acid FDB76_06565 ENOG4105CZJ Aldehyde dehydrogenase FDB76_06590 ENOG4105MWK D-amino acid dehydrogenase, small subunit FDB76_06610 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDB76_06625 ENOG4108Z4X TRANSCRIPTIONal FDB76_06640 ENOG4105WPN DNA integration recombination invertion protein FDB76_06655 ENOG4105DJ2 Major Facilitator Superfamily FDB76_06660 ENOG4107Y2X deaminase FDB76_06670 ENOG4105EMY transcriptional regulator FDB76_06700 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDB76_06710 ENOG4105UYK outer membrane protein a FDB76_06795 ENOG4108HW3 (ABC) transporter FDB76_06805 ENOG4105MRR Transcriptional regulator (By similarity) FDB76_06825 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF FDB76_06830 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FDB76_06845 ENOG4105E2A Dehydrogenase FDB76_06855 ENOG4105R8C Transcriptional regulator FDB76_06880 ENOG4107R4J Chloride channel FDB76_06885 ENOG4108JIK carboxylase FDB76_06905 ENOG4105C5A transporter FDB76_06910 ENOG4108WAV Transcriptional regulator FDB76_06925 ENOG4105CNA YD repeat protein FDB76_06965 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) FDB76_06985 ENOG4105D2S major facilitator superfamily FDB76_07000 ENOG4105D1S lipid A biosynthesis FDB76_07005 ENOG4105BZU Histidine kinase FDB76_07010 ENOG4107AQZ Membrane FDB76_07030 ENOG4108Z4U Ferredoxin FDB76_07070 ENOG4105DFG type I secretion outer membrane protein FDB76_07075 ENOG4108IUZ ABC transporter FDB76_07080 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA FDB76_07090 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase FDB76_07095 ENOG4105C2X Arabinose 5-phosphate isomerase FDB76_07130 ENOG4107YPT transcriptional regulator FDB76_07165 ENOG4105II7 pyrroline-5-carboxylate reductase FDB76_07175 ENOG4105VEQ Cold shock protein FDB76_07180 ENOG410829K Lysine exporter protein (Lyse ygga) FDB76_07215 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FDB76_07270 ENOG4108KB2 LysR family Transcriptional regulator FDB76_07275 ENOG4105FUY alpha subunit FDB76_07280 ENOG4108UKV benzoate 1,2-dioxygenase FDB76_07285 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein FDB76_07290 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase FDB76_07295 ENOG4105DKK Benzoate FDB76_07300 ENOG4105D2S major facilitator superfamily FDB76_07315 ENOG4105CQ7 ATP-dependent helicase FDB76_07330 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FDB76_07340 ENOG4108JU3 Alkyl hydroperoxide reductase FDB76_07350 ENOG4108K3A Glutathione S-transferase FDB76_07360 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) FDB76_07365 ENOG4108TGY Glutathione S-transferase FDB76_07375 ENOG4108ZG0 Ompa motb domain protein FDB76_07380 ENOG4105CD3 dihydroorotase FDB76_07410 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FDB76_07425 ENOG4108UKZ OsmC family FDB76_07430 ENOG4107RYR Transcriptional regulator, Crp Fnr family FDB76_07440 ENOG4105CPC Aldo Keto reductase FDB76_07455 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FDB76_07465 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FDB76_07475 ENOG4105CFH Aspartokinase FDB76_07485 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FDB76_07495 ENOG4105CPW cytochrome b561 FDB76_07500 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) FDB76_07505 ENOG4105C7N Xanthine uracil vitamin C permease FDB76_07515 ENOG4105F95 Monooxygenase FDB76_07590 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDB76_07610 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) FDB76_07635 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component FDB76_07640 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component FDB76_07650 ENOG4105E9H Lytic Murein transglycosylase FDB76_07650 ENOG4105E9H Lytic Murein transglycosylase FDB76_07655 ENOG4107RZZ dna polymerase iii epsilon subunit FDB76_07665 ENOG4105E09 nadh pyrophosphatase FDB76_07675 ENOG4105W4M Transport-associated protein FDB76_07685 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FDB76_07695 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) FDB76_07700 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FDB76_07720 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family FDB76_07725 ENOG4105D0A hydroxylase FDB76_07730 ENOG4107RAQ aminopeptidase FDB76_08145 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FDB76_08170 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FDB76_08180 ENOG4105D82 Glutamate dehydrogenase FDB76_08185 ENOG4108R3D Electron transport complex FDB76_08190 ENOG4105CSM endonuclease III FDB76_08215 ENOG4105CJN penicillin-binding protein FDB76_08220 ENOG4106H78 methyltransferase FDB76_08235 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FDB76_08245 ENOG4105CQM Urea amidohydrolase subunit alpha FDB76_08275 ENOG4107RET Isocitrate lyase FDB76_08285 ENOG4105C37 (CBS) domain FDB76_08295 ENOG4105D4T Citrate transporter FDB76_08310 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) FDB76_08330 ENOG4108MRJ FDB76_08350 ENOG4105VCQ rubredoxin FDB76_08355 ENOG4107QZF nitrite reductase NADPH large subunit FDB76_08365 ENOG4105C5Q Transcriptional regulator FDB76_08385 ENOG4107U91 Rhomboid family FDB76_08390 ENOG4105CV6 ABC transporter, permease FDB76_08395 ENOG4108I0Y (ABC) transporter FDB76_08420 ENOG4107RNH Outer membrane receptor FepA FDB76_08435 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) FDB76_08440 ENOG4105E6M Sulphatase-modifying factor protein FDB76_08460 ENOG4105CJ3 phosphate transporter FDB76_08480 ENOG4105CSP Major Facilitator Superfamily FDB76_08490 ENOG4108PZW LysR family Transcriptional regulator FDB76_08505 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) FDB76_08510 ENOG4105EU0 Major facilitator Superfamily FDB76_08515 ENOG4108R6W Transcriptional regulator, ARAC family FDB76_08520 ENOG4105CSV Glutaminase FDB76_08525 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FDB76_08530 ENOG4105CSH Transporter FDB76_08540 ENOG4105C7K acetolactate synthase FDB76_08555 ENOG4105CHR reductase FDB76_08560 ENOG4108MXF Alpha Beta Hydrolase FDB76_08570 ENOG4105DJB Major Facilitator Superfamily FDB76_08575 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase FDB76_08585 ENOG4105CHR reductase FDB76_08605 ENOG41069M3 Transcriptional regulator FDB76_08620 ENOG4106YT9 Enoyl-CoA hydratase FDB76_08630 ENOG4105CND Glycosyl transferase, family 2 FDB76_08635 ENOG4107BJW polysaccharide deacetylase FDB76_08645 ENOG4108VWS Yaeq family FDB76_08655 ENOG4105CKI cobalamin synthesis protein FDB76_08675 ENOG4105C94 Transporter FDB76_08680 ENOG4105C94 Transporter FDB76_08685 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FDB76_08710 ENOG4107QK5 Homocysteine s-methyltransferase FDB76_08715 ENOG4105D5Q Arginine ornithine antiporter FDB76_08740 ENOG4108YNN Heme oxygenase FDB76_08770 ENOG4108SF5 RNA Polymerase FDB76_08780 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDB76_08785 ENOG4105C54 Major Facilitator superfamily FDB76_08805 ENOG4105F8V Hydrolase, tatD family FDB76_08895 ENOG4105DFP Integrase FDB76_09030 ENOG4105K4U addiction module toxin, RelE StbE family FDB76_09315 ENOG41083X2 DNA polymerase III, epsilon subunit FDB76_09380 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) FDB76_09385 ENOG4105C0R drug resistance transporter emrb qaca subfamily FDB76_09390 ENOG4105CW7 secretion protein, HlyD family FDB76_09395 ENOG4108VUY thioesterase Superfamily protein FDB76_09400 ENOG4105D52 delta-aminolevulinic acid dehydratase FDB76_09405 ENOG4105MWK D-amino acid dehydrogenase, small subunit FDB76_09410 ENOG4105ECP epimerase FDB76_09435 ENOG4107RH8 nuclease SbcCD subunit D FDB76_09440 ENOG4105EYH Exonuclease FDB76_09445 ENOG4105DFA alanine racemase domain protein FDB76_09450 ENOG4105CZX twitching motility protein FDB76_09455 ENOG4105CZX twitching motility protein FDB76_09460 ENOG41090R7 Ferric uptake FDB76_09490 ENOG4105E7A Glutamine amidotransferase FDB76_09505 ENOG4107QKV phosphomannomutase FDB76_09515 ENOG4105C4R Atp-dependent dna helicase FDB76_09520 ENOG4108ZG0 Ompa motb domain protein FDB76_09525 ENOG4106HNH Acyl-transferase FDB76_09540 ENOG4107QMS site-determining protein FDB76_09565 ENOG4105CNU cell division protein FtsK FDB76_09570 ENOG4105C3M thioredoxin reductase FDB76_09575 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) FDB76_09585 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FDB76_09630 ENOG4108YXA Membrane FDB76_09635 ENOG4105EUB pirin domain protein FDB76_09645 ENOG4105C4K Nad synthetase FDB76_09660 ENOG4105E3J oxidoreductase FDB76_09665 ENOG4105C26 Dehydrogenase FDB76_09670 ENOG4105DVW rieske (2Fe-2S) FDB76_09680 ENOG4105C94 Transporter FDB76_09685 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDB76_09690 ENOG4105EJC lysr family transcriptional regulator FDB76_09710 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding FDB76_09730 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FDB76_09735 ENOG4105C34 Pseudouridine synthase FDB76_09740 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane FDB76_09745 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FDB76_09760 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) FDB76_09790 ENOG4105C5T Phosphoribosyl pyrophosphate synthase FDB76_09820 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FDB76_09830 ENOG4105DWF phosphomethylpyrimidine kinase FDB76_09835 ENOG4109066 lysm domain bon superfamily protein FDB76_09845 ENOG4105CHR reductase FDB76_09850 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FDB76_09860 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein FDB76_09865 ENOG4108BPE -transporting atpase FDB76_09870 ENOG4107RTD sua5 ycio yrdc ywlc family protein FDB76_09875 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) FDB76_09880 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) FDB76_09885 ENOG4105FE9 pseudouridine synthase FDB76_09895 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FDB76_09900 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FDB76_09910 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FDB76_09915 ENOG4108K4C ec 3.1.3.12 FDB76_09920 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase FDB76_09925 ENOG4106UW1 Major Facilitator superfamily FDB76_09945 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FDB76_09955 ENOG4105HF0 Membrane FDB76_09970 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY FDB76_09980 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) FDB76_10040 ENOG4105D1F ATP-binding protein FDB76_10050 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FDB76_10080 ENOG4105K6H D-cysteine desulfhydrase FDB76_10085 ENOG4105CBX hi0933 family FDB76_10110 ENOG4105DP0 ferredoxin-NADP reductase FDB76_10115 ENOG4105DUM transcriptional regulator, lysR family FDB76_10135 ENOG4105C8S subunit m FDB76_10140 ENOG4105D65 subunit l FDB76_10150 ENOG4107UFS subunit j FDB76_10165 ENOG4108IEH NADH dehydrogenase subunit g FDB76_10170 ENOG4107QIZ NADH dehydrogenase FDB76_10175 ENOG4105GKE subunit e FDB76_10195 ENOG4105BZU Histidine kinase FDB76_10205 ENOG4105E0F Histidine kinase FDB76_10210 ENOG4107EXC regulatoR FDB76_10220 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDB76_10230 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FDB76_10310 ENOG4105DZG Dehydrogenase FDB76_10330 ENOG4105JAB phenazine biosynthesis protein, phzf family FDB76_10360 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) FDB76_10365 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FDB76_10375 ENOG4105ETT transcriptional Regulator, LysR family FDB76_10395 ENOG4105CH2 amidohydrolase FDB76_10405 ENOG4106P55 Transcriptional regulator FDB76_10425 ENOG4106P55 Transcriptional regulator FDB76_10430 ENOG4107EFR Flavocytochrome c FDB76_10440 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F FDB76_10445 ENOG4107RGD Major Facilitator superfamily FDB76_10450 ENOG4105C1G acyl-Coa dehydrogenase FDB76_10455 ENOG4105ETT transcriptional Regulator, LysR family FDB76_10490 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FDB76_10495 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FDB76_10500 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDB76_10515 ENOG4105VR0 copper resistance FDB76_10520 ENOG4105E3B Multicopper oxidase FDB76_10530 ENOG4108HCJ Hydrolase FDB76_10535 ENOG4105DJV ribulose-phosphate 3-epimerase FDB76_10560 ENOG41072GX Peptidase M22 Glycoprotease FDB76_10565 ENOG4108Z0R Transferase FDB76_10625 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FDB76_10630 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FDB76_10635 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FDB76_10705 ENOG4105K56 Transcriptional regulator FDB76_10710 ENOG4108ZHJ Organic hydroperoxide resistance protein FDB76_10715 ENOG4107QHF type ii secretion system protein e FDB76_10745 ENOG4105C2M dna polymerase I FDB76_10750 ENOG4108VIA integral membrane protein FDB76_10755 ENOG4105II7 pyrroline-5-carboxylate reductase FDB76_10760 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FDB76_10770 ENOG4105C9X ppx gppa phosphatase FDB76_10780 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FDB76_10800 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FDB76_10825 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) FDB76_10840 ENOG4105W39 Membrane FDB76_10845 ENOG4105CYM Glutathione S-transferase FDB76_10865 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_10870 ENOG4105N42 UPF0307 protein FDB76_10875 ENOG41080Z8 PHOSPHOCARRIER protein FDB76_10895 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FDB76_10900 ENOG4105DJ0 Poly(A) Polymerase FDB76_10905 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein FDB76_10910 ENOG4105DXN mazG family FDB76_10920 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDB76_10935 ENOG4105C6T cysteine synthase FDB76_10940 ENOG4105BZU Histidine kinase FDB76_10945 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase FDB76_10950 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDB76_10955 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) FDB76_10970 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDB76_10975 ENOG4105W8H transhydrogenase (subunit alpha FDB76_10980 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) FDB76_10985 ENOG4106UX7 integral membrane protein FDB76_11000 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDB76_11010 ENOG4107RSM transcriptional regulator FDB76_11020 ENOG4105CUZ uba thif-type nad fad binding protein FDB76_11030 ENOG4107QM5 aconitate hydratase FDB76_11035 ENOG4105F8V Hydrolase, tatD family FDB76_11050 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) FDB76_11080 ENOG4105BZU Histidine kinase FDB76_11090 ENOG4108ZP8 Acetolactate synthase small subunit FDB76_11095 ENOG4105C7K acetolactate synthase FDB76_11120 ENOG4105DJY efflux transporter, rnd family, mfp subunit FDB76_11125 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FDB76_11130 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDB76_11135 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH FDB76_11145 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) FDB76_11150 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FDB76_11160 ENOG4105VW4 glutaredoxin 3 FDB76_11180 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDB76_11185 ENOG4105C2D reductase FDB76_11195 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FDB76_11225 ENOG4105C84 Histidine ammonia-lyase FDB76_11240 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_11255 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) FDB76_11275 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) FDB76_11295 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) FDB76_11315 ENOG4105WVQ Fe-S assembly protein IscX FDB76_11345 ENOG4106HB6 Alpha beta hydrolase FDB76_11355 ENOG4105C26 Dehydrogenase FDB76_11360 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family FDB76_11365 ENOG4105C6Z Gluconate FDB76_11370 ENOG4108UHU Aldolase FDB76_11375 ENOG4105C01 Dihydroxy-acid dehydratase FDB76_11385 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FDB76_11390 ENOG4108DNC Involved in acetate metabolism (By similarity) FDB76_11395 ENOG4107GFK fumarate FDB76_11415 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FDB76_11435 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) FDB76_11445 ENOG4105DWV Homoserine O-trans-acetylase FDB76_11545 ENOG4105CIY formyltetrahydrofolate deformylase FDB76_11555 ENOG4107RGH Aldehyde dehydrogenase FDB76_11560 ENOG4105KDC 50s ribosomal protein l28 FDB76_11565 ENOG4105W0E 50S ribosomal protein L33 FDB76_11570 ENOG4105CKD glutathione-regulated potassium-efflux system protein FDB76_11590 ENOG4105VFU Rna-binding protein FDB76_11595 ENOG4105C4R Atp-dependent dna helicase FDB76_11610 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FDB76_11620 ENOG4105KVH Transcriptional regulator FDB76_11630 ENOG41069P5 Protein slyX homolog FDB76_11635 ENOG4105C5H ABC transporter FDB76_11640 ENOG4105N14 lysine exporter protein LysE YggA FDB76_11645 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase FDB76_11655 ENOG4105CK2 sodium dicarboxylate symporter FDB76_11710 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) FDB76_11735 ENOG4105DUM transcriptional regulator, lysR family FDB76_11760 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase FDB76_11775 ENOG4108W5M transcriptional regulator FDB76_11790 ENOG4105D29 Helix-turn-helix type 11 domain protein FDB76_11795 ENOG4107XGZ Hydrolase FDB76_11800 ENOG4105EI2 Pseudouridine synthase FDB76_11810 ENOG4105C03 ribonuclease FDB76_11830 ENOG4105CBN LysR family transcriptional regulator FDB76_11835 ENOG4105EMU Dehydrogenase FDB76_11840 ENOG4105CSA Coproporphyrinogen iii oxidase FDB76_11850 ENOG4107QI1 Mate efflux family protein FDB76_11860 ENOG4107T8P acyl-Coa dehydrogenase FDB76_11905 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) FDB76_11910 ENOG4105C5X domain protein FDB76_11925 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FDB76_11935 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase FDB76_11940 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) FDB76_11945 ENOG4108JU5 Magnesium and cobalt efflux protein FDB76_11950 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) FDB76_11955 ENOG4108Z7R Chaperone CsaA FDB76_11965 ENOG4108VAU general secretion pathway protein G FDB76_11970 ENOG4105D7Q type ii secretion system FDB76_11975 ENOG4105C25 Primosomal protein n' FDB76_11980 ENOG4105CKD glutathione-regulated potassium-efflux system protein FDB76_11985 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) FDB76_11995 ENOG4105DVC DnaJ domain protein FDB76_12000 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) FDB76_12005 ENOG4107QUT magnesium and cobalt transport protein CorA FDB76_12025 ENOG4107QYX exodeoxyribonuclease v alpha FDB76_12030 ENOG4107QKA exodeoxyribonuclease V beta FDB76_12035 ENOG4105DSY exodeoxyribonuclease V, gamma FDB76_12045 ENOG4105CSR polyphosphate kinase 2 FDB76_12055 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FDB76_12070 ENOG41061H0 Monooxygenase FDB76_12075 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase FDB76_12090 ENOG4105D65 subunit l FDB76_12095 ENOG4108ZE9 Monovalent cation H antiporter subunit C FDB76_12100 ENOG4107R4Z monovalent cation h antiporter subunit d FDB76_12105 ENOG4105SC1 monovalent cation H antiporter subunit E FDB76_12110 ENOG4105W4C monovalent cation H antiporter subunit F FDB76_12115 ENOG4105KJM monovalent cation h antiporter subunit g FDB76_12130 ENOG4105CHV Transcription elongation factor NusA FDB76_12155 ENOG4107EJC Preprotein translocase subunit SecG FDB76_12165 ENOG4107QHF type ii secretion system protein e FDB76_12180 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FDB76_12190 ENOG4105C2N RNA methyltransferase TrmH family group 3 FDB76_12205 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FDB76_12215 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) FDB76_12245 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FDB76_12250 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FDB76_12320 ENOG4107ZXU DSBA oxidoreductase FDB76_12335 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) FDB76_12350 ENOG4105D3Y Na H antiporter FDB76_12355 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FDB76_12405 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FDB76_12410 ENOG4105PM1 preprotein translocase subunit SecE FDB76_12450 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FDB76_12455 ENOG4105TV9 FHA Domain-Containing protein FDB76_12460 ENOG4105GVR general secretion pathway protein D FDB76_12475 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FDB76_12500 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) FDB76_12505 ENOG4108NEV two component transcriptional regulator, LytTR family FDB76_12510 ENOG4108HRK Histidine kinase FDB76_12525 ENOG4108UTW Plays a role in the regulation of phosphate uptake FDB76_12530 ENOG4105DFG type I secretion outer membrane protein FDB76_12535 ENOG4108RNG Permease of the drug metabolite transporter FDB76_12560 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FDB76_12565 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters FDB76_12570 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) FDB76_12575 ENOG4105CNI cell division protein FtsW FDB76_12590 ENOG4105CE1 Ferrous iron transport protein b FDB76_12600 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDB76_12605 ENOG4105T95 Thiol disulfide interChange protein FDB76_12610 ENOG4105D6E homoserine dehydrogenase FDB76_12620 ENOG41061WM D-Alanyl-D-Alanine FDB76_12630 ENOG4107TUY Histidine kinase FDB76_12635 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FDB76_12640 ENOG4105CN1 protease FDB76_12645 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FDB76_12650 ENOG4108K5H permease YjgP YjgQ family protein FDB76_12690 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FDB76_12700 ENOG4105BZU Histidine kinase FDB76_12715 ENOG4105C0P Mg chelatase subunit ChlI FDB76_12725 ENOG4108R0M Aminoglycoside FDB76_12780 ENOG4108HWY Beta-lactamase FDB76_12795 ENOG4105F6A helicase FDB76_12810 ENOG4105CHH sulfate transporter FDB76_12845 ENOG4105C0P Mg chelatase subunit ChlI FDB76_12905 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDB76_12915 ENOG4105EPF Outer membrane porin FDB76_12920 ENOG4105F0N pyrophosphate phospho-hydrolase FDB76_12935 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_12940 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDB76_12945 ENOG41079KZ Major Facilitator Superfamily FDB76_12950 ENOG4105EN6 Membrane FDB76_12960 ENOG4105EE5 Membrane protein terC FDB76_12965 ENOG4108URH decarboxylase FDB76_12980 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FDB76_12995 ENOG4105CCT upf0313 protein FDB76_13015 ENOG4105CS1 NAD(P)H quinone oxidoreductase FDB76_13025 ENOG4105C6T cysteine synthase FDB76_13060 ENOG4105Y7M Transcriptional regulator, TetR family FDB76_13095 ENOG4105C79 DNA protecting protein DprA FDB76_13110 ENOG4108IND Tetr family transcriptional regulator FDB76_13115 ENOG4107RTG Major Facilitator superfamily FDB76_13125 ENOG4108V06 Glutathione peroxidase FDB76_13165 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) FDB76_13195 ENOG4105FAV ABC, transporter FDB76_13205 ENOG4105EZR dyp-type peroxidase family protein FDB76_13215 ENOG4107R1I NAD-dependent malic enzyme FDB76_13240 ENOG4105EUB pirin domain protein FDB76_13260 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FDB76_13265 ENOG4106MP8 UPF0754 membrane protein FDB76_13270 ENOG4108VBZ doxx family FDB76_13275 ENOG4105DQR SNARE associated Golgi FDB76_13290 ENOG4107QJE Chromosome Partitioning Protein FDB76_13300 ENOG4107PSF BolA-like protein FDB76_13335 ENOG4105ZTP Protein of unknown function (DUF1376) FDB76_13420 ENOG41080IJ Diacylglycerol kinase FDB76_13430 ENOG4105DHQ Histidine kinase FDB76_13435 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDB76_13440 ENOG4105DIJ Phosphoethanolamine transferase FDB76_13450 ENOG4105KT5 UmuD protein FDB76_13455 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FDB76_13470 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) FDB76_13500 ENOG4107Z6W Protein CrcB homolog FDB76_13510 ENOG4105CHH sulfate transporter FDB76_13530 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) FDB76_13565 ENOG4105F9F transposase FDB76_13590 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) FDB76_13595 ENOG4105VF7 tolerance protein FDB76_13600 ENOG4105EPC oxidoreductase FDB76_13605 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase FDB76_13670 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FDB76_13695 ENOG4105C1G acyl-Coa dehydrogenase FDB76_13725 ENOG4105E39 Enoyl-CoA hydratase FDB76_13730 ENOG4105E39 Enoyl-CoA hydratase FDB76_13735 ENOG4105C1G acyl-Coa dehydrogenase FDB76_13745 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FDB76_13750 ENOG4105C26 Dehydrogenase FDB76_13760 ENOG4105C85 amino acid FDB76_13765 ENOG4105C85 amino acid FDB76_13770 ENOG4105M4H endoribonuclease L-psp FDB76_13785 ENOG4105EW9 transcriptional regulator AsnC family FDB76_13810 ENOG4105D3G Pseudouridine synthase FDB76_13865 ENOG4105DQ6 Transposase FDB76_13900 ENOG4108I0Z Aconitate hydratase FDB76_13905 ENOG4105BZN citrate synthase FDB76_13910 ENOG4105CR4 methylisocitrate lyase FDB76_13915 ENOG4105DRR Transcriptional regulator, GntR family FDB76_13925 ENOG4105CGF Aromatic amino acid aminotransferase FDB76_13930 ENOG4105CXG d-lactate dehydrogenase FDB76_13940 ENOG41073TP transcriptional regulator FDB76_13945 ENOG4105DAA L-lactate FDB76_13950 ENOG4107QKV phosphomannomutase FDB76_13955 ENOG4105CMR udp-glucose 4-epimerase FDB76_13965 ENOG4105C6Y Udp-glucose 6-dehydrogenase FDB76_13970 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FDB76_13985 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) FDB76_14000 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FDB76_14055 ENOG4105F0R Cytidylyltransferase FDB76_14070 ENOG4105D2T synthase FDB76_14075 ENOG4107SE4 UDP-N-acetylglucosamine 2-epimerase FDB76_14080 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase FDB76_14090 ENOG4107QQG Dehydrogenase FDB76_14095 ENOG4105DAY polysaccharide export protein FDB76_14105 ENOG4105D75 Capsular exopolysaccharide family FDB76_14110 ENOG4108V1T peptidylprolyl cis-trans isomerase FDB76_14115 ENOG4108V1T peptidylprolyl cis-trans isomerase FDB76_14120 ENOG4105CJR Integral membrane protein (MviN FDB76_14125 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase FDB76_14130 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FDB76_14140 ENOG4105HSS phospholipase C FDB76_14165 ENOG41062JF Transcriptional regulator FDB76_14185 ENOG4105UBK short-chain dehydrogenase reductase FDB76_14200 ENOG4107QZM n-acetylglutamate synthase FDB76_14205 ENOG4105GVF (ABC) transporter FDB76_14210 ENOG4105GVF (ABC) transporter FDB76_14215 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FDB76_14220 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FDB76_14225 ENOG4108VM9 ABC, transporter FDB76_14230 ENOG4108R86 Transcriptional regulator FDB76_14235 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FDB76_14245 ENOG4105DTN riboflavin biosynthesis protein ribF FDB76_14250 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FDB76_14260 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase FDB76_14425 ENOG4105C1G acyl-Coa dehydrogenase FDB76_14430 ENOG4108RZE Tetr family transcriptional regulator FDB76_14450 ENOG4107QX3 carboxylase FDB76_14455 ENOG4105C1G acyl-Coa dehydrogenase FDB76_14475 ENOG4105KB2 stringent starvation protein b FDB76_14480 ENOG4107MKT Stringent starvation protein a FDB76_14485 ENOG4108UJD 30S ribosomal protein S9 FDB76_14495 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) FDB76_14500 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) FDB76_14505 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FDB76_14525 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FDB76_14535 ENOG4107RZC phospholipase d FDB76_14545 ENOG4105UYK outer membrane protein a FDB76_14550 ENOG4108KHX Diguanylate cyclase FDB76_14585 ENOG4107QN2 dihydrolipoyl dehydrogenase FDB76_14595 ENOG4107QPB Beta-lactamase domain protein FDB76_14600 ENOG4107U2T alpha beta FDB76_14610 ENOG4105NAU thioesterase Superfamily protein FDB76_14640 ENOG4105K9H YciI-like protein FDB76_14650 ENOG4105DB7 PHP domain protein FDB76_14655 ENOG4105FFC UPF0187 protein FDB76_14665 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FDB76_14670 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDB76_14675 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FDB76_14680 ENOG4105VIE preprotein translocase, subunit YajC FDB76_14710 ENOG4105BZU Histidine kinase FDB76_14715 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) FDB76_14720 ENOG4105CM2 brancheD-chain amino acid aminotransferase FDB76_14735 ENOG4107BJW polysaccharide deacetylase FDB76_14790 ENOG4105UGU tonB-dependent Receptor FDB76_14810 ENOG4108VY7 phosphate-starvation-inducible protein PsiE FDB76_14815 ENOG4108K3A Glutathione S-transferase FDB76_14820 ENOG4108R4R Iron-regulated virulence regulatory protein FDB76_14825 ENOG4105CSU acyl-Coa dehydrogenase FDB76_14830 ENOG4105CSU acyl-Coa dehydrogenase FDB76_14840 ENOG4105EB3 Histidine kinase FDB76_14850 ENOG4105CNG UPF0061 protein FDB76_14870 ENOG4108WBT adenosyltransferase FDB76_14885 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) FDB76_14920 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FDB76_14940 ENOG4105D3R alkyl hydroperoxide reductase FDB76_14955 ENOG4105CSH Transporter FDB76_14960 ENOG4108UT2 hemolysin iii FDB76_14990 ENOG4105CHU acetyl-coa acetyltransferase FDB76_14995 ENOG4108R6W Transcriptional regulator, ARAC family FDB76_15005 ENOG4105TW1 Carbohydrate-selective porin OprB FDB76_15010 ENOG4105DZG Dehydrogenase FDB76_15015 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FDB76_15025 ENOG410814C multidrug resistance protein FDB76_15035 ENOG4105CHU acetyl-coa acetyltransferase FDB76_15045 ENOG4108WHA ompa motb domain protein FDB76_15055 ENOG4105E0Y RtcB Protein FDB76_15060 ENOG4108IQI permease FDB76_15070 ENOG4105C2W permease FDB76_15090 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FDB76_15100 ENOG4108VX5 3-methyladenine DNA glycosylase FDB76_15105 ENOG4105CHB tonB-dependent Receptor FDB76_15120 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDB76_15135 ENOG4105T95 Thiol disulfide interChange protein FDB76_15140 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) FDB76_15150 ENOG4105K78 MarR family Transcriptional regulator FDB76_15155 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FDB76_15160 ENOG4105KWI UPF0339 protein FDB76_15185 ENOG4108UNF response regulator FDB76_15190 ENOG4105M3Z response regulator FDB76_15200 ENOG4105C8Q Methyl-accepting chemotaxis FDB76_15205 ENOG4105CBS Chea signal transduction histidine kinase FDB76_15220 ENOG4106HKS Entericidin EcnA/B family FDB76_15230 ENOG4105WD1 Membrane FDB76_15235 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FDB76_15275 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FDB76_15285 ENOG4105EM2 membrane FDB76_15290 ENOG4105C2C drug resistance transporter, Bcr CflA FDB76_15310 ENOG4105BZG amino acid carrier protein FDB76_15315 ENOG4105D78 K07001 NTE family protein FDB76_15320 ENOG4105C7B Threonine dehydratase FDB76_15365 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FDB76_15375 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) FDB76_15380 ENOG4105DFF Rod shape-determining protein mreb FDB76_15385 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) FDB76_15390 ENOG4105VQ7 Rod shape-determining protein MreD FDB76_15395 ENOG4108Z03 MAF-like protein FDB76_15400 ENOG4105C03 ribonuclease FDB76_15410 ENOG4105D8T Acyltransferase FDB76_15420 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein FDB76_15430 ENOG4108X0B nad(p)h dehydrogenase (quinone) FDB76_15455 ENOG4105CF7 AraC family transcriptional regulator FDB76_15475 ENOG4105C85 amino acid FDB76_15480 ENOG4105C7F AcnD-accessory protein PrpF FDB76_15485 ENOG4105CTB Polyprenyl synthetase FDB76_15490 ENOG4105MSB protein, conserved in bacteria FDB76_15505 ENOG4105D78 K07001 NTE family protein FDB76_15530 ENOG4105XJC Two component transcriptional regulator (Winged helix family FDB76_15535 ENOG4105DHQ Histidine kinase FDB76_15555 ENOG4108M0I Transcriptional regulator FDB76_15575 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FDB76_15600 ENOG4105K8R UPF0145 protein FDB76_15605 ENOG4105ENJ RND efflux system, outer membrane lipoprotein FDB76_15610 ENOG4105BZS acriflavin resistance protein FDB76_15615 ENOG4105C1P efflux transporter, rnd family, mfp subunit FDB76_15620 ENOG410841Q phosphoesterase PA-phosphatase related protein FDB76_15650 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) FDB76_15665 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FDB76_15670 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FDB76_15685 ENOG4105CUB amino acid FDB76_15700 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) FDB76_15705 ENOG41084BA UPF0250 protein FDB76_15710 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FDB76_15745 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit FDB76_15750 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein FDB76_15760 ENOG4105E33 succinate dehydrogenase FDB76_15775 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FDB76_15780 ENOG4105C7S Dehydrogenase FDB76_15785 ENOG4107QN2 dihydrolipoyl dehydrogenase FDB76_15795 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FDB76_15805 ENOG4105CKW Inner membrane protein yedI FDB76_15810 ENOG4105CGZ zinc metallopeptidase FDB76_15815 ENOG4105EEQ Na H antiporter FDB76_15870 ENOG41080TK Universal stress protein FDB76_15885 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FDB76_15890 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain FDB76_15905 ENOG4105HBR Rna-binding protein FDB76_15915 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FDB76_15920 ENOG4105EEI dihydropteroate synthase FDB76_15970 ENOG4105CSH Transporter FDB76_15975 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) FDB76_15980 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FDB76_15995 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) FDB76_16015 ENOG41080IJ Diacylglycerol kinase FDB76_16025 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase FDB76_16030 ENOG4105BZS acriflavin resistance protein FDB76_16045 ENOG4105E4C Lytic transglycosylase catalytic FDB76_16070 ENOG4108RRZ Transcription elongation factor GreB FDB76_16085 ENOG4105CEY Amp-dependent synthetase and ligase FDB76_16130 ENOG4105BZW Glycerate kinase FDB76_16135 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit FDB76_16140 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FDB76_16155 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) FDB76_16165 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FDB76_16170 ENOG4105C85 amino acid FDB76_16180 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FDB76_16190 ENOG4105N14 lysine exporter protein LysE YggA FDB76_16195 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FDB76_16200 ENOG4105BZJ Electron transfer flavoprotein FDB76_16205 ENOG4105C10 Electron transfer flavoprotein FDB76_16210 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDB76_16245 ENOG4107KET secretion protein, HlyD family FDB76_16275 ENOG4105D60 lipoprotein releasing system transmembrane protein FDB76_16280 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FDB76_16285 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FDB76_16295 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) FDB76_16300 ENOG4107R6F Alpha Beta Hydrolase Fold protein FDB76_16305 ENOG4108V3E phosphoribosylglycinamide formyltransferase FDB76_16315 ENOG4105C02 permease FDB76_16365 ENOG4105KCK Peptidoglycan-associated lipoprotein FDB76_16370 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) FDB76_16380 ENOG4105M8F Biopolymer transport protein exbD tolR FDB76_16385 ENOG4105E02 MotA TolQ exbB proton channel FDB76_16390 ENOG4107YD3 Thioesterase FDB76_16395 ENOG4105CH2 amidohydrolase FDB76_16415 ENOG4108ETH Formylglycinamide ribotide synthetase FDB76_16420 ENOG4105C2C drug resistance transporter, Bcr CflA FDB76_16425 ENOG4105EGD dinuclear metal center protein, YbgI family FDB76_16430 ENOG4108UKI Enoyl-CoA hydratase FDB76_16445 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FDB76_16460 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FDB76_16465 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FDB76_16480 ENOG4107R11 Transcriptional regulator FDB76_16485 ENOG4108IJ6 ABC transporter FDB76_16495 ENOG4108I5D sulfate abc transporter FDB76_16505 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FDB76_16510 ENOG4105YAZ 4-amino-4-deoxychorismate lyase FDB76_16515 ENOG4105HHA aminodeoxychorismate lyase FDB76_16530 ENOG4108IYU L-aspartate oxidase FDB76_16535 ENOG4105C0H protease FDB76_16550 ENOG4105C3F Signal peptidase i FDB76_16565 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FDB76_16575 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) FDB76_16580 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) FDB76_16585 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase FDB76_16590 ENOG4105EMU Dehydrogenase FDB76_16640 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FDB76_16650 ENOG4105DTR rard protein FDB76_16685 ENOG4107QS8 (LipO)protein FDB76_16690 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FDB76_16695 ENOG4105EA8 2-Nitropropane dioxygenase FDB76_16725 ENOG4107R8N Glycosyl transferase, family 2 FDB76_16740 ENOG4105CVP deoxyribo-dipyrimidine photolyase FDB76_16745 ENOG4108YZY peptidylprolyl cis-trans isomerase FDB76_16750 ENOG4105CEP NADH dehydrogenase FDB76_16755 ENOG4105DZ1 carboxypeptidase FDB76_16765 ENOG4105E9K Isocitrate dehydrogenase FDB76_16770 ENOG4108R99 pseudouridine synthase FDB76_17030 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FDB76_17035 ENOG4105D6S protein involved in catabolism of external DNA FDB76_17065 ENOG4105E4C Lytic transglycosylase catalytic FDB76_17075 ENOG4105C9A Phoh family FDB76_17105 ENOG4105CS1 NAD(P)H quinone oxidoreductase FDB76_17120 ENOG4108K2B transcriptional regulator FDB76_17125 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase FDB76_17170 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FDB76_17175 ENOG4105DGW oligopeptidase A FDB76_17180 ENOG4105VKU nucleicacid-binding protein FDB76_17215 ENOG4105C1G acyl-Coa dehydrogenase FDB76_17240 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) FDB76_17250 ENOG41067V7 50S ribosomal protein L36 FDB76_17255 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FDB76_17365 ENOG41089BK Glutamine amido-transferase FDB76_17370 ENOG4105C28 cystathionine FDB76_17385 ENOG4105KPV Transcriptional regulator FDB76_17400 ENOG4105CK2 sodium dicarboxylate symporter FDB76_17405 ENOG4105C29 acyl-CoA thioesterase FDB76_17425 ENOG4105CB5 ATP-dependent DNA helicase recG FDB76_17450 ENOG4108URH decarboxylase FDB76_17455 ENOG4105D7N magnesium and cobalt transport protein CorA FDB76_17475 ENOG4105CY3 ABC transporter, permease FDB76_17480 ENOG4105DHJ ABC, transporter FDB76_17490 ENOG4105C1J atp-dependent rna helicase FDB76_17495 ENOG4105ECY inositol monophosphatase FDB76_17510 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) FDB76_17525 ENOG4105CSU acyl-Coa dehydrogenase FDB76_17535 ENOG41067S9 phage shock protein C, PspC FDB76_17540 ENOG4105W87 Cbs domain FDB76_17600 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin FDB76_17625 ENOG4105C26 Dehydrogenase FDB76_17635 ENOG4105C8Y Acetylornithine aminotransferase FDB76_17640 ENOG4105D82 Glutamate dehydrogenase FDB76_17645 ENOG4108IQI permease FDB76_17675 ENOG4107SKI cobyrinic Acid a,c-diamide synthase FDB76_17680 ENOG4105IPI Membrane FDB76_17685 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FDB76_17690 ENOG4105EM2 membrane FDB76_17695 ENOG4107QF7 multi-drug FDB76_17705 ENOG4105NF4 modulator of drug activity FDB76_17710 ENOG4105VRH Antibiotic biosynthesis monooxygenase FDB76_17720 ENOG4105CQB FAD linked oxidase domain protein FDB76_17725 ENOG4108JQ1 Dehydrogenase FDB76_17750 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FDB76_17755 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) FDB76_17760 ENOG4107IFA Lipase (EC 3.1.1.3) FDB76_17775 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) FDB76_17825 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) FDB76_17840 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FDB76_17845 ENOG4105KME endoribonuclease L-psp FDB76_17855 ENOG4108UQY Iron-storage protein FDB76_17860 ENOG4108YSG O-Antigen polymerase FDB76_17880 ENOG4108HWY Beta-lactamase FDB76_17910 ENOG4105HA9 of methanol dehydrogenase type FDB76_17915 ENOG4108V0P LemA family FDB76_17925 ENOG4105BZ8 glutamate synthase FDB76_17930 ENOG4105CBC glutamate synthase FDB76_17950 ENOG4105E4G Type IV pilus FDB76_17975 ENOG4108JQC penicillin-binding protein 1A FDB76_17980 ENOG4105DHI Methyltransferase FDB76_17995 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) FDB76_18000 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FDB76_18005 ENOG4105CJN penicillin-binding protein FDB76_18020 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FDB76_18045 ENOG4108IQI permease FDB76_18130 ENOG4105C5H ABC transporter FDB76_18140 ENOG4105PDP Short chain dehydrogenase FDB76_18145 ENOG4105CHH sulfate transporter FDB76_18155 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FDB76_18160 ENOG4105E0F Histidine kinase FDB76_18170 ENOG4105CYC Transferase FDB76_18200 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FDB76_18230 ENOG41061CK Antibiotic biosynthesis monooxygenase FDB76_18245 ENOG4105CUV Homoserine Kinase FDB76_18310 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FDB76_18320 ENOG4105KVH Transcriptional regulator FDB76_18355 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) FDB76_18360 ENOG4105CPC Aldo Keto reductase FDB76_18380 ENOG4106NZI LysR family Transcriptional regulator FDB76_18385 ENOG4105D94 Major Facilitator Superfamily FDB76_18410 ENOG4105EUB pirin domain protein FDB76_18415 ENOG4105CHJ isochorismatase hydrolase FDB76_18425 ENOG4105C26 Dehydrogenase FDB76_18430 ENOG4108JPW Aminotransferase FDB76_18440 ENOG4105C85 amino acid FDB76_18450 ENOG4108UMN azlc family FDB76_18460 ENOG4108UUM single-stranded DNA-binding protein FDB76_18465 ENOG4107RDB Major Facilitator FDB76_18475 ENOG4105DWF phosphomethylpyrimidine kinase FDB76_18480 ENOG4105RA2 Membrane FDB76_18490 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FDB76_18495 ENOG4108WUH Transcriptional regulator, TetR family FDB76_18500 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FDB76_18510 ENOG4105BZU Histidine kinase FDB76_18520 ENOG4105C94 Transporter FDB76_18530 ENOG4107QN1 sodium solute FDB76_18535 ENOG41062QD Membrane FDB76_18540 ENOG4105BZU Histidine kinase FDB76_18555 ENOG4108UZX fmn reductase FDB76_18560 ENOG4105FBW Monooxygenase FDB76_18575 ENOG4108W2Y isochorismatase FDB76_18580 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FDB76_18590 ENOG4105D64 Mechanosensitive ion channel FDB76_18600 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase FDB76_18605 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FDB76_18625 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FDB76_18640 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FDB76_18655 ENOG4105E0K tonB-dependent siderophore receptor FDB76_18670 ENOG4107QSN dihydrolipoamide acetyltransferase FDB76_18675 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) FDB76_18680 ENOG41063SB peptidase FDB76_18695 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FDB76_18700 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FDB76_18705 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) FDB76_18725 ENOG4105D7Z glutathione synthase FDB76_18745 ENOG4105CGK Exodeoxyribonuclease III FDB76_18750 ENOG4105KUZ arsenate reductase FDB76_18765 ENOG4105BZU Histidine kinase FDB76_18770 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) FDB76_18800 ENOG41084YZ Hydrolase FDB76_18815 ENOG41061H0 Monooxygenase FDB76_18825 ENOG4108Z2U ureidoglycolate hydrolase FDB76_18830 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FDB76_18840 ENOG4105IPS esterase FDB76_18865 ENOG4105CS6 Rhs element vgr protein FDB76_18875 ENOG4105D9M gamma-glutamylcysteine synthetase FDB76_18890 ENOG4106BRA Membrane FDB76_18895 ENOG4105CHM Aminotransferase FDB76_18900 ENOG4107QJQ Mate efflux family protein FDB76_18915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FDB76_18920 ENOG4105BZU Histidine kinase FDB76_18950 ENOG4105KHC sulfurtransferase FDB76_18990 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FDB76_19005 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) FDB76_19010 ENOG4108ZAI phosphatidylglycerophosphatase a FDB76_19020 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FDB76_19025 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FDB76_19040 ENOG41088SP formiminoglutamate hydrolase FDB76_19050 ENOG4105C85 amino acid FDB76_19065 ENOG41090B9 response to stress FDB76_19070 ENOG4105CZE histidine utilization repressor FDB76_19080 ENOG4105CKI cobalamin synthesis protein FDB76_19090 ENOG4105C85 amino acid FDB76_19100 ENOG4108RXX maleylacetoacetate isomerase FDB76_19120 ENOG4105EWC Purine nucleoside phosphorylase FDB76_19130 ENOG4105C09 Bile acid FDB76_19135 ENOG4108RWI nicotinamidase FDB76_19140 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FDB76_19160 ENOG4105S64 Formate nitrite transporter FDB76_19165 ENOG4105D1H recombination factor protein RarA FDB76_19175 ENOG4108ZZ3 UPF0260 protein FDB76_19195 ENOG4105CEN a g-specific adenine glycosylase FDB76_19210 ENOG4108R3E Dna-3-methyladenine glycosylase i FDB76_19215 ENOG4105DQ4 alcohol dehydrogenase FDB76_19235 ENOG4105HEI LysR family (Transcriptional regulator FDB76_19240 ENOG4105CV8 reductase FDB76_19245 ENOG4105F27 Major Facilitator FDB76_19280 ENOG4105DJY efflux transporter, rnd family, mfp subunit FDB76_19285 ENOG4108IG5 Transcriptional regulator FDB76_19295 ENOG4105C2W permease FDB76_19300 ENOG4108W5M transcriptional regulator FDB76_19325 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FDB76_19335 ENOG4105C8J )-transporter FDB76_19375 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) FDB76_19425 ENOG4105CVE Lytic murein transglycosylase FDB76_19430 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FDB76_19435 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FDB76_19450 ENOG4105DFU Cell wall formation (By similarity) FDB76_19460 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FDB76_19465 ENOG4105DU1 integral membrane protein, terc FDB76_19475 ENOG4106032 Glutathionylspermidine synthase FDB76_19485 ENOG4107QUY Guanine deaminase FDB76_19490 ENOG4108UGV hypoxanthine phosphoribosyltransferase FDB76_19500 ENOG4105T95 Thiol disulfide interChange protein FDB76_19505 ENOG4105PGM cation diffusion facilitator family transporter FDB76_19520 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FDB76_19535 ENOG4105VG0 50S ribosomal protein l34 FDB76_19545 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FDB76_19555 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FDB76_19565 ENOG4105DQR SNARE associated Golgi FDB76_19570 ENOG4105C5H ABC transporter FDB76_19575 ENOG4108821 RND type efflux pump FDB76_19580 ENOG4108821 RND type efflux pump FDB76_19585 ENOG4108821 RND type efflux pump FDB76_19600 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) FDB76_19605 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FDB76_19725 ENOG4105KK6 nuclease FDB76_19730 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS FDB76_19785 ENOG4105FA0 parb-like partition protein FDB76_19805 ENOG4105CDW Resistance protein FDB76_19850 ENOG4105F9F transposase FDB76_19910 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) FDB76_20075 ENOG4105K5T PilT protein FDB76_20110 ENOG4105T95 Thiol disulfide interChange protein FDB76_20240 ENOG4105NVB glycoside hydrolase, family 19 FDB76_20730 ENOG4105WD1 Membrane