locus-tag	class	description
C5B74_00045	COG3077	Addiction module antitoxin, RelB DinJ family
C5B74_00050	COG0659	secondary active sulfate transmembrane transporter activity
C5B74_00055	COG0589	response to stress
C5B74_00065	COG3316	Transposase and inactivated derivatives
C5B74_00080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5B74_00095	COG0583	DNA-binding transcription factor activity
C5B74_00120	COG3316	Transposase and inactivated derivatives
C5B74_00140	COG3316	Transposase and inactivated derivatives
C5B74_00170	COG1192	Involved in chromosome partitioning
C5B74_00195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C5B74_00215	COG2433	Pfam Transposase IS66
C5B74_00225	COG3316	Transposase and inactivated derivatives
C5B74_00300	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5B74_00305	COG3657	addiction module killer protein
C5B74_00340	COG0592	DNA-directed DNA polymerase activity
C5B74_00350	COG0187	DNA topoisomerase II activity
C5B74_00360	COG0586	Pfam SNARE associated Golgi protein
C5B74_00365	COG0488	(ABC) transporter
C5B74_00390	COG0596	Alpha beta hydrolase
C5B74_00395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C5B74_00400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5B74_00445	COG0733	neurotransmitter:sodium symporter activity
C5B74_00485	COG2233	PERMEase
C5B74_00500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_00535	COG2814	Major facilitator Superfamily
C5B74_00540	COG0656	L-ascorbic acid biosynthetic process
C5B74_00545	COG0583	DNA-binding transcription factor activity
C5B74_00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5B74_00565	COG1064	alcohol dehydrogenase
C5B74_00570	COG2818	Glycosylase
C5B74_00585	COG1194	a g-specific adenine glycosylase
C5B74_00605	COG2983	Belongs to the UPF0260 family
C5B74_00610	COG2133	pyrroloquinoline quinone binding
C5B74_00615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5B74_00620	COG2116	formate transmembrane transporter activity
C5B74_00640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5B74_00645	COG1335	isochorismatase
C5B74_00650	COG0385	Bile acid
C5B74_00655	COG0534	Mate efflux family protein
C5B74_00660	COG1683	Conserved Protein
C5B74_00680	COG0625	glutathione transferase activity
C5B74_00690	COG1113	amino acid transport
C5B74_00700	COG0523	cobalamin synthesis protein
C5B74_00710	COG2188	Transcriptional regulator
C5B74_00740	COG0010	Belongs to the arginase family
C5B74_00760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5B74_00765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C5B74_00775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5B74_00780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C5B74_00885	COG0534	Mate efflux family protein
C5B74_00890	COG0436	Aminotransferase
C5B74_00895	COG2733	membrane
C5B74_00910	COG2918	glutathione biosynthetic process
C5B74_00920	COG3501	Rhs element vgr protein
C5B74_00925	COG0791	NLP P60 protein
C5B74_00925	COG1388	LysM domain
C5B74_00945	COG3150	esterase
C5B74_00955	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_00960	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
C5B74_00970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5B74_00980	COG2233	PERMEase
C5B74_00985	COG2351	hydroxyisourate hydrolase activity
C5B74_01020	COG3706	GGDEF domain
C5B74_01035	COG1393	Belongs to the ArsC family
C5B74_01040	COG0708	Exodeoxyribonuclease III
C5B74_01060	COG0189	ligase activity
C5B74_01080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5B74_01090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5B74_01105	COG4942	peptidase
C5B74_01115	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5B74_01125	COG2119	membrane
C5B74_01130	COG4774	siderophore transport
C5B74_01135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_01135	COG0426	domain, Protein
C5B74_01160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5B74_01180	COG1902	pentaerythritol trinitrate reductase activity
C5B74_01185	COG1519	Transferase
C5B74_01190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5B74_01195	COG0668	transmembrane transport
C5B74_01205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5B74_01210	COG1335	isochorismatase
C5B74_01215	COG1522	sequence-specific DNA binding
C5B74_01220	COG3328	transposase activity
C5B74_01245	COG2205	protein histidine kinase activity
C5B74_01245	COG2198	Histidine kinase
C5B74_01245	COG0784	Response regulator, receiver
C5B74_01250	COG3162	membrane
C5B74_01255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5B74_01265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5B74_01275	COG3706	GGDEF domain
C5B74_01285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5B74_01290	COG1309	transcriptional regulator
C5B74_01310	COG0351	phosphomethylpyrimidine kinase
C5B74_01310	COG0352	thiamine-phosphate diphosphorylase activity
C5B74_01310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C5B74_01320	COG2814	Major facilitator Superfamily
C5B74_01335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C5B74_01345	COG1113	amino acid transport
C5B74_01355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5B74_01360	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_01370	COG1335	isochorismatase
C5B74_01400	COG2814	Major facilitator Superfamily
C5B74_01405	COG0583	DNA-binding transcription factor activity
C5B74_01425	COG0667	Aldo Keto reductase
C5B74_01460	COG1733	regulation of RNA biosynthetic process
C5B74_01470	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5B74_01535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5B74_01550	COG2329	Antibiotic biosynthesis monooxygenase
C5B74_01580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C5B74_01610	COG0427	acetyl-CoA hydrolase
C5B74_01625	COG0745	RESPONSE REGULATOR receiver
C5B74_01635	COG0659	secondary active sulfate transmembrane transporter activity
C5B74_01640	COG4221	oxidoreductase activity
C5B74_01650	COG0488	(ABC) transporter
C5B74_01735	COG0833	amino acid
C5B74_01780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C5B74_01785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5B74_01800	COG2226	methyltransferase
C5B74_01850	COG0070	glutamate synthase
C5B74_01850	COG0067	glutamate synthase
C5B74_01850	COG0069	glutamate synthase activity
C5B74_01855	COG0493	'glutamate synthase
C5B74_01865	COG1704	LemA family
C5B74_01870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5B74_01885	COG3307	-O-antigen
C5B74_01905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5B74_01920	COG0194	GDP metabolic process
C5B74_01970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5B74_01990	COG5380	lipid catabolic process
C5B74_01995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C5B74_02020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5B74_02025	COG0277	FAD linked oxidase domain protein
C5B74_02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5B74_02040	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5B74_02055	COG1289	transmembrane transporter activity
C5B74_02065	COG0628	permease
C5B74_02070	COG1192	Involved in chromosome partitioning
C5B74_02100	COG0833	amino acid
C5B74_02105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5B74_02110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5B74_02120	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_02160	COG0583	DNA-binding transcription factor activity
C5B74_02205	COG0517	IMP dehydrogenase activity
C5B74_02210	COG1983	PspC domain protein
C5B74_02220	COG1960	acyl-CoA dehydrogenase activity
C5B74_02235	COG0408	coproporphyrinogen oxidase activity
C5B74_02255	COG0513	Belongs to the DEAD box helicase family
C5B74_02260	COG1127	ABC transporter
C5B74_02265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C5B74_02275	COG2854	intermembrane phospholipid transfer
C5B74_02285	COG0598	Magnesium transport protein CorA
C5B74_02295	COG0494	nUDIX hydrolase
C5B74_02300	COG1040	competence protein
C5B74_02305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5B74_02325	COG1946	Acyl-CoA thioesterase
C5B74_02330	COG1301	dicarboxylic acid transport
C5B74_02345	COG1959	2 iron, 2 sulfur cluster binding
C5B74_02350	COG1017	nitric oxide dioxygenase activity
C5B74_02350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5B74_02355	COG0433	COG0433 Predicted ATPase
C5B74_02360	COG0626	cystathionine gamma-synthase activity
C5B74_02480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5B74_02490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5B74_02515	COG1960	acyl-CoA dehydrogenase activity
C5B74_02520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C5B74_02550	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C5B74_02555	COG0339	signal peptide processing
C5B74_02560	COG0557	exoribonuclease II activity
C5B74_02605	COG0179	Fumarylacetoacetate (FAA) hydrolase
C5B74_02610	COG2169	Transcriptional regulator
C5B74_02615	COG0697	spore germination
C5B74_02620	COG1295	ribonuclease BN
C5B74_02655	COG1702	phosphate starvation-inducible protein PhoH
C5B74_02665	COG0741	lytic transglycosylase activity
C5B74_02665	COG1196	nuclear chromosome segregation
C5B74_02665	COG0739	heme binding
C5B74_02695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C5B74_02700	COG1183	phosphatidylcholine synthase activity
C5B74_02745	COG1960	acyl-CoA dehydrogenase activity
C5B74_02750	COG1309	transcriptional regulator
C5B74_02765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5B74_02770	COG1960	acyl-CoA dehydrogenase activity
C5B74_02790	COG2969	positive regulation of protein catabolic process
C5B74_02800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C5B74_02815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5B74_02820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5B74_02840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5B74_02850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5B74_02855	COG1408	metallophosphoesterase
C5B74_02865	COG2199	diguanylate cyclase activity
C5B74_02910	COG3453	Protein conserved in bacteria
C5B74_02910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5B74_02925	COG1607	acyl-coa hydrolase
C5B74_02955	COG2350	Protein conserved in bacteria
C5B74_02965	COG0613	PHP domain protein
C5B74_02970	COG3781	membrane
C5B74_02980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5B74_02985	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5B74_02995	COG1862	Preprotein translocase
C5B74_03045	COG2205	protein histidine kinase activity
C5B74_03050	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5B74_03070	COG0726	polysaccharide deacetylase
C5B74_03075	COG0463	Glycosyl transferase, family 2
C5B74_03080	COG0438	transferase activity, transferring glycosyl groups
C5B74_03145	COG0625	glutathione transferase activity
C5B74_03150	COG0583	DNA-binding transcription factor activity
C5B74_03155	COG1960	acyl-CoA dehydrogenase activity
C5B74_03160	COG1960	acyl-CoA dehydrogenase activity
C5B74_03170	COG2205	protein histidine kinase activity
C5B74_03175	COG0745	RESPONSE REGULATOR receiver
C5B74_03180	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C5B74_03200	COG2096	Adenosyltransferase
C5B74_03215	COG0133	tryptophan synthase activity
C5B74_03250	COG0285	dihydrofolate synthase activity
C5B74_03270	COG0450	alkyl hydroperoxide reductase
C5B74_03285	COG0477	Major facilitator Superfamily
C5B74_03290	COG1272	protein, Hemolysin III
C5B74_03320	COG0183	Belongs to the thiolase family
C5B74_03325	COG2207	Transcriptional regulator
C5B74_03345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5B74_03365	COG0183	Belongs to the thiolase family
C5B74_03375	COG2885	chlorophyll binding
C5B74_03375	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C5B74_03385	COG1690	Belongs to the RtcB family
C5B74_03390	COG0833	amino acid
C5B74_03400	COG2233	PERMEase
C5B74_03430	COG2094	Belongs to the DNA glycosylase MPG family
C5B74_03435	COG4772	TonB-dependent receptor
C5B74_03440	COG1902	pentaerythritol trinitrate reductase activity
C5B74_03455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5B74_03460	COG0354	folic acid binding
C5B74_03470	COG3189	MarR family transcriptional regulator
C5B74_03475	COG2824	Alkylphosphonate utilization operon protein PhnA
C5B74_03480	COG3422	double-strand break repair
C5B74_03520	COG0840	transmembrane signaling receptor activity
C5B74_03540	COG5510	response to toxic substance
C5B74_03550	COG2832	Protein of unknown function (DUF454)
C5B74_03555	COG1376	ErfK ybiS ycfS ynhG family protein
C5B74_03605	COG1289	transmembrane transporter activity
C5B74_03610	COG2814	Major facilitator Superfamily
C5B74_03630	COG1115	amino acid carrier protein
C5B74_03635	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5B74_03640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5B74_03645	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C5B74_03675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5B74_03685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C5B74_03690	COG1077	Cell shape determining protein MreB Mrl
C5B74_03695	COG1792	Involved in formation and maintenance of cell shape
C5B74_03700	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C5B74_03705	COG0424	maF-like protein
C5B74_03710	COG1530	ribonuclease E activity
C5B74_03720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5B74_03740	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5B74_03765	COG2207	Transcriptional regulator
C5B74_03785	COG1113	amino acid transport
C5B74_03790	COG2828	Protein conserved in bacteria
C5B74_03795	COG0142	geranyltranstransferase activity
C5B74_03800	COG2315	Protein conserved in bacteria
C5B74_03815	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5B74_03840	COG2194	sulfuric ester hydrolase activity
C5B74_03845	COG0745	RESPONSE REGULATOR receiver
C5B74_03850	COG0642	Histidine kinase
C5B74_03860	COG0004	ammonium transporteR
C5B74_03870	COG0583	DNA-binding transcription factor activity
C5B74_03890	COG0525	valine-tRNA ligase activity
C5B74_03900	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_03910	COG0393	Putative heavy-metal-binding
C5B74_03915	COG0393	Putative heavy-metal-binding
C5B74_03920	COG1538	Outer membrane efflux protein
C5B74_03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_03935	COG0671	phosphoesterase, PA-phosphatase related
C5B74_03965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5B74_03980	COG1648	precorrin-2 dehydrogenase activity
C5B74_03980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5B74_03985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C5B74_03990	COG1733	regulation of RNA biosynthetic process
C5B74_04000	COG0531	amino acid
C5B74_04015	COG0321	lipoyl(octanoyl) transferase activity
C5B74_04020	COG2921	Belongs to the UPF0250 family
C5B74_04060	COG2009	succinate dehydrogenase
C5B74_04065	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C5B74_04070	COG1053	succinate dehydrogenase
C5B74_04075	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5B74_04100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5B74_04120	COG2354	Protein conserved in bacteria
C5B74_04125	COG2321	neutral zinc metallopeptidase
C5B74_04160	COG2843	Capsule synthesis protein
C5B74_04175	COG0589	response to stress
C5B74_04195	COG0505	Belongs to the CarA family
C5B74_04220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5B74_04225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5B74_04275	COG0477	Major facilitator Superfamily
C5B74_04280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5B74_04300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5B74_04330	COG2433	Pfam Transposase IS66
C5B74_04340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5B74_04345	COG0584	glycerophosphoryl diester phosphodiesterase
C5B74_04365	COG0741	lytic transglycosylase activity
C5B74_04390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5B74_04405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5B74_04435	COG0778	Nitroreductase
C5B74_04450	COG1929	Belongs to the glycerate kinase type-1 family
C5B74_04455	COG0243	molybdopterin cofactor binding
C5B74_04460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5B74_04465	COG3339	Conserved Protein
C5B74_04475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C5B74_04490	COG1113	amino acid transport
C5B74_04500	COG0019	diaminopimelate decarboxylase activity
C5B74_04510	COG1280	lysine exporter protein (LysE YggA)
C5B74_04515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C5B74_04545	COG0463	Glycosyl transferase, family 2
C5B74_04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_04595	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5B74_04600	COG1136	(ABC) transporter
C5B74_04605	COG2333	competence protein COMEC
C5B74_04605	COG0658	competence protein
C5B74_04615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5B74_04615	COG0616	signal peptide processing
C5B74_04620	COG0596	Alpha beta hydrolase
C5B74_04625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5B74_04635	COG0628	permease
C5B74_04670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5B74_04690	COG0823	Involved in the tonB-independent uptake of proteins
C5B74_04710	COG0824	Thioesterase
C5B74_04715	COG1473	amidohydrolase
C5B74_04735	COG0047	phosphoribosylformylglycinamidine synthase activity
C5B74_04735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5B74_04740	COG2814	Major facilitator Superfamily
C5B74_04745	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5B74_04750	COG1024	Enoyl-CoA hydratase
C5B74_04755	COG1051	belongs to the nudix hydrolase family
C5B74_04755	COG1056	cytidyltransferase-related domain
C5B74_04765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5B74_04780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C5B74_04795	COG4625	pathogenesis
C5B74_04800	COG0583	DNA-binding transcription factor activity
C5B74_04805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C5B74_04810	COG4208	sulfate ABC transporter
C5B74_04815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C5B74_04825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C5B74_04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5B74_04835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5B74_04855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5B74_04870	COG0681	Belongs to the peptidase S26 family
C5B74_04885	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C5B74_04895	COG1381	Involved in DNA repair and RecF pathway recombination
C5B74_04900	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C5B74_04910	COG4221	oxidoreductase activity
C5B74_04960	COG0556	nucleotide-excision repair
C5B74_05155	COG5410	chromosome segregation
C5B74_05345	COG2070	2-Nitropropane dioxygenase
C5B74_05375	COG1215	transferase activity, transferring glycosyl groups
C5B74_05390	COG0415	Belongs to the DNA photolyase family
C5B74_05400	COG1252	NADH dehydrogenase
C5B74_05405	COG1686	Belongs to the peptidase S11 family
C5B74_05420	COG1187	pseudouridine synthase activity
C5B74_05445	COG0477	Major facilitator Superfamily
C5B74_05450	COG0583	DNA-binding transcription factor activity
C5B74_05465	COG0612	Peptidase, M16
C5B74_05490	COG0352	thiamine-phosphate diphosphorylase activity
C5B74_05525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5B74_05540	COG1309	transcriptional regulator
C5B74_05550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C5B74_05555	COG0076	glutamate decarboxylase activity
C5B74_05565	COG1522	sequence-specific DNA binding
C5B74_05570	COG3961	Belongs to the TPP enzyme family
C5B74_05575	COG1113	amino acid transport
C5B74_05580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C5B74_05585	COG0573	inorganic phosphate transmembrane transporter activity
C5B74_05595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5B74_05600	COG0616	signal peptide processing
C5B74_05635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C5B74_05640	COG1686	Belongs to the peptidase S11 family
C5B74_05665	COG0583	DNA-binding transcription factor activity
C5B74_05670	COG1067	ATP-dependent peptidase activity
C5B74_05715	COG1966	Carbon starvation protein
C5B74_05720	COG2879	small protein
C5B74_05755	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C5B74_05755	COG2508	Transcriptional regulator
C5B74_05775	COG1113	amino acid transport
C5B74_05780	COG0583	DNA-binding transcription factor activity
C5B74_05785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5B74_05790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5B74_05805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5B74_05810	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C5B74_05810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5B74_05845	COG2814	Major facilitator Superfamily
C5B74_05850	COG4948	Mandelate Racemase Muconate Lactonizing
C5B74_05860	COG1309	transcriptional regulator
C5B74_05880	COG1741	Belongs to the pirin family
C5B74_05890	COG2964	Protein conserved in bacteria
C5B74_05905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5B74_05910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5B74_05915	COG4605	iron ion homeostasis
C5B74_05920	COG4604	ABC transporter, ATP-binding protein
C5B74_05925	COG4607	ABC-type enterochelin transport system periplasmic component
C5B74_05930	COG4774	siderophore transport
C5B74_05940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5B74_05945	COG1021	2,3-dihydroxybenzoate-AMP ligase
C5B74_05950	COG1535	isochorismatase
C5B74_05950	COG3433	isochorismatase activity
C5B74_05965	COG1132	(ABC) transporter
C5B74_05975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C5B74_05985	COG1169	isochorismate synthase
C5B74_06000	COG3739	integral membrane protein
C5B74_06030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C5B74_06060	COG0308	aminopeptidase N
C5B74_06065	COG0512	Glutamine amidotransferase of anthranilate synthase
C5B74_06075	COG3104	oligopeptide transport
C5B74_06090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C5B74_06125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5B74_06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5B74_06135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5B74_06155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5B74_06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C5B74_06165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C5B74_06180	COG1960	acyl-CoA dehydrogenase activity
C5B74_06185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5B74_06190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5B74_06200	COG2223	nitrite transmembrane transporter activity
C5B74_06210	COG0024	Methionine aminopeptidase
C5B74_06215	COG0052	Belongs to the universal ribosomal protein uS2 family
C5B74_06230	COG2207	Transcriptional regulator
C5B74_06255	COG2951	lytic endotransglycosylase activity
C5B74_06260	COG0772	Belongs to the SEDS family
C5B74_06275	COG0842	Transport permease protein
C5B74_06280	COG1131	(ABC) transporter
C5B74_06315	COG1538	Outer membrane efflux protein
C5B74_06325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_06350	COG4215	(ABC) transporter
C5B74_06355	COG4160	amino acid transport
C5B74_06360	COG4598	ABC transporter
C5B74_06370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5B74_06380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5B74_06395	COG1720	tRNA m6t6A37 methyltransferase activity
C5B74_06415	COG0745	RESPONSE REGULATOR receiver
C5B74_06420	COG0642	Histidine kinase
C5B74_06430	COG0494	nUDIX hydrolase
C5B74_06440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5B74_06445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5B74_06450	COG3139	Protein of unknown function (DUF1315)
C5B74_06455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5B74_06465	COG1301	dicarboxylic acid transport
C5B74_06470	COG1960	acyl-CoA dehydrogenase activity
C5B74_06475	COG2819	hydrolase of the alpha beta superfamily
C5B74_06485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5B74_06495	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5B74_06500	COG1234	tRNA 3'-trailer cleavage
C5B74_06530	COG2363	Small membrane protein
C5B74_06550	COG0513	Belongs to the DEAD box helicase family
C5B74_06560	COG0778	Nitroreductase
C5B74_06590	COG1286	toxin biosynthetic process
C5B74_06615	COG4783	chaperone-mediated protein folding
C5B74_06620	COG1610	YqeY-like protein
C5B74_06625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C5B74_06720	COG3111	PFAM Bacterial OB fold (BOF) protein
C5B74_06745	COG3243	poly(R)-hydroxyalkanoic acid synthase
C5B74_06750	COG0786	glutamate:sodium symporter activity
C5B74_06760	COG2186	Transcriptional regulator
C5B74_06810	COG0477	Major facilitator Superfamily
C5B74_06840	COG2985	domain, Protein
C5B74_06850	COG2995	paraquat-inducible protein a
C5B74_06855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5B74_06855	COG3008	intermembrane lipid transfer
C5B74_06865	COG1794	racemase activity, acting on amino acids and derivatives
C5B74_06895	COG1301	dicarboxylic acid transport
C5B74_06905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5B74_06910	COG2011	ABC-type metal ion transport system permease component
C5B74_06915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5B74_06920	COG1464	Belongs to the NlpA lipoprotein family
C5B74_06925	COG0151	Belongs to the GarS family
C5B74_06930	COG0138	bifunctional purine biosynthesis protein purh
C5B74_06935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C5B74_06965	COG2308	Evidence 4 Homologs of previously reported genes of
C5B74_06975	COG1305	Transglutaminase-like
C5B74_06985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5B74_06990	COG0305	Participates in initiation and elongation during chromosome replication
C5B74_07015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C5B74_07025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5B74_07030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5B74_07055	COG0726	polysaccharide deacetylase
C5B74_07055	COG1649	PFAM Uncharacterised BCR, COG1649
C5B74_07060	COG1215	transferase activity, transferring glycosyl groups
C5B74_07065	COG3658	cytochrome
C5B74_07075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5B74_07095	COG0583	DNA-binding transcription factor activity
C5B74_07115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5B74_07120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5B74_07135	COG1960	acyl-CoA dehydrogenase activity
C5B74_07140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5B74_07145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_07170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C5B74_07175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C5B74_07185	COG2205	protein histidine kinase activity
C5B74_07190	COG0745	RESPONSE REGULATOR receiver
C5B74_07195	COG0174	glutamine synthetase
C5B74_07215	COG0729	surface antigen
C5B74_07245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5B74_07250	COG2814	Major facilitator Superfamily
C5B74_07265	COG0583	DNA-binding transcription factor activity
C5B74_07280	COG1187	pseudouridine synthase activity
C5B74_07300	COG0802	atpase or kinase
C5B74_07305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5B74_07315	COG1923	regulation of RNA biosynthetic process
C5B74_07320	COG0697	spore germination
C5B74_07335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5B74_07350	COG0519	Catalyzes the synthesis of GMP from XMP
C5B74_07350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5B74_07355	COG4302	ethanolamine ammonia-lyase activity
C5B74_07360	COG4303	Ethanolamine ammonia lyase large subunit
C5B74_07365	COG0531	amino acid
C5B74_07385	COG1454	alcohol dehydrogenase
C5B74_07390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5B74_07400	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C5B74_07420	COG0308	aminopeptidase N
C5B74_07430	COG4221	oxidoreductase activity
C5B74_07440	COG1605	Chorismate mutase
C5B74_07460	COG1309	transcriptional regulator
C5B74_07470	COG0668	transmembrane transport
C5B74_07500	COG4773	Receptor
C5B74_07520	COG0488	(ABC) transporter
C5B74_07525	COG0589	response to stress
C5B74_07540	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C5B74_07550	COG3135	benzoate transporter
C5B74_07555	COG1522	sequence-specific DNA binding
C5B74_07570	COG0583	DNA-binding transcription factor activity
C5B74_07580	COG0183	Belongs to the thiolase family
C5B74_07610	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5B74_07620	COG0824	Thioesterase
C5B74_07625	COG1454	alcohol dehydrogenase
C5B74_07635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C5B74_07655	COG0069	glutamate synthase activity
C5B74_07675	COG2814	Major facilitator Superfamily
C5B74_07690	COG0511	ligase activity, forming carbon-carbon bonds
C5B74_07710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5B74_07710	COG1116	anion transmembrane transporter activity
C5B74_07715	COG0745	RESPONSE REGULATOR receiver
C5B74_07725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5B74_07725	COG2146	nitrite reductase [NAD(P)H] activity
C5B74_07730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5B74_07735	COG0243	molybdopterin cofactor binding
C5B74_07745	COG0243	molybdopterin cofactor binding
C5B74_07750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C5B74_07765	COG0315	cyclic pyranopterin monophosphate synthase activity
C5B74_07765	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5B74_07770	COG0303	'Molybdopterin
C5B74_07780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5B74_07785	COG0697	spore germination
C5B74_07805	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C5B74_07810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5B74_07870	COG2204	response regulator
C5B74_07875	COG3852	Histidine kinase
C5B74_07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5B74_07905	COG0575	Belongs to the CDS family
C5B74_07940	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5B74_07955	COG2137	regulation of response to DNA damage stimulus
C5B74_07965	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C5B74_07970	COG1011	Hydrolase
C5B74_07995	COG1522	sequence-specific DNA binding
C5B74_08005	COG1113	amino acid transport
C5B74_08020	COG0659	secondary active sulfate transmembrane transporter activity
C5B74_08035	COG3316	Transposase and inactivated derivatives
C5B74_08065	COG1132	(ABC) transporter
C5B74_08120	COG0482	sulfurtransferase activity
C5B74_08140	COG3173	Aminoglycoside phosphotransferase
C5B74_08150	COG2433	Pfam Transposase IS66
C5B74_08175	COG3316	Transposase and inactivated derivatives
C5B74_08195	COG5001	Diguanylate cyclase
C5B74_08195	COG3300	MHYT domain
C5B74_08215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5B74_08215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5B74_08215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C5B74_08220	COG1105	Belongs to the carbohydrate kinase PfkB family
C5B74_08225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5B74_08225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5B74_08255	COG0024	Methionine aminopeptidase
C5B74_08260	COG0583	DNA-binding transcription factor activity
C5B74_08270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C5B74_08275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5B74_08280	COG0517	IMP dehydrogenase activity
C5B74_08280	COG0516	GMP reductase activity
C5B74_08305	COG0552	protein localization to endoplasmic reticulum
C5B74_08315	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C5B74_08330	COG4890	Cyd operon protein YbgT
C5B74_08335	COG1294	oxidase, subunit
C5B74_08350	COG1585	Membrane protein implicated in regulation of membrane protease activity
C5B74_08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5B74_08365	COG4774	siderophore transport
C5B74_08380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5B74_08385	COG0569	domain protein
C5B74_08390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C5B74_08420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C5B74_08425	COG0542	response to heat
C5B74_08435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5B74_08450	COG1902	pentaerythritol trinitrate reductase activity
C5B74_08450	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5B74_08495	COG2323	membrane
C5B74_08500	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5B74_08510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5B74_08515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5B74_08520	COG0183	Belongs to the thiolase family
C5B74_08525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5B74_08530	COG0596	Alpha beta hydrolase
C5B74_08535	COG2271	Major facilitator Superfamily
C5B74_08540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5B74_08545	COG3485	protocatechuate 3,4-dioxygenase
C5B74_08550	COG3485	protocatechuate 3,4-dioxygenase
C5B74_08555	COG0710	3-dehydroquinate dehydratase activity
C5B74_08560	COG3420	alginic acid biosynthetic process
C5B74_08565	COG3659	wide pore channel activity
C5B74_08570	COG4993	Dehydrogenase
C5B74_08580	COG2391	methyltransferase activity
C5B74_08595	COG1414	Transcriptional regulator
C5B74_08600	COG0583	DNA-binding transcription factor activity
C5B74_08605	COG1960	acyl-CoA dehydrogenase activity
C5B74_08630	COG2814	Major facilitator Superfamily
C5B74_08640	COG0154	amidase activity
C5B74_08660	COG4638	Rieske (2fe-2S)
C5B74_08670	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_08680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_08690	COG3733	amine oxidase
C5B74_08700	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_08710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5B74_08715	COG0183	Belongs to the thiolase family
C5B74_08720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5B74_08725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5B74_08735	COG4829	muconolactone delta-isomerase
C5B74_08740	COG4948	Mandelate Racemase Muconate Lactonizing
C5B74_08745	COG0583	DNA-binding transcription factor activity
C5B74_08755	COG2186	Transcriptional regulator
C5B74_08775	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_08795	COG1960	acyl-CoA dehydrogenase activity
C5B74_08800	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_08805	COG3829	transcription factor binding
C5B74_08815	COG3162	membrane
C5B74_08830	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_08845	COG0753	catalase activity
C5B74_08870	COG1846	Transcriptional regulator
C5B74_08875	COG1902	pentaerythritol trinitrate reductase activity
C5B74_08875	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5B74_08885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5B74_08915	COG1309	transcriptional regulator
C5B74_08925	COG1335	isochorismatase
C5B74_08930	COG0583	DNA-binding transcription factor activity
C5B74_08940	COG0475	glutathione-regulated potassium exporter activity
C5B74_08940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5B74_08950	COG1473	amidohydrolase
C5B74_08965	COG2831	hemolysin activation secretion protein
C5B74_08970	COG3210	domain, Protein
C5B74_09015	COG0583	DNA-binding transcription factor activity
C5B74_09040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5B74_09045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5B74_09065	COG1566	PFAM secretion protein HlyD family protein
C5B74_09080	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_09085	COG0129	dihydroxy-acid dehydratase activity
C5B74_09095	COG0583	DNA-binding transcription factor activity
C5B74_09100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5B74_09110	COG2084	Dehydrogenase
C5B74_09115	COG2207	Transcriptional regulator
C5B74_09130	COG1064	alcohol dehydrogenase
C5B74_09145	COG1120	ATPase activity
C5B74_09165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5B74_09285	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C5B74_09340	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_09355	COG2207	Transcriptional regulator
C5B74_09365	COG2205	protein histidine kinase activity
C5B74_09370	COG0745	RESPONSE REGULATOR receiver
C5B74_09375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_09380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5B74_09385	COG1538	Outer membrane efflux protein
C5B74_09395	COG2072	flavoprotein involved in K transport
C5B74_09415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5B74_09435	COG3539	Fimbrial protein
C5B74_09465	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C5B74_09475	COG0753	catalase activity
C5B74_09490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5B74_09555	COG3433	isochorismatase activity
C5B74_09555	COG1535	isochorismatase
C5B74_09560	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_09565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C5B74_09570	COG4149	molybdate abc transporter
C5B74_09575	COG0725	ABC transporter, periplasmic molybdate-binding protein
C5B74_09585	COG4638	Rieske (2fe-2S)
C5B74_09590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C5B74_09595	COG0543	2 iron, 2 sulfur cluster binding
C5B74_09595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5B74_09610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_09620	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_09625	COG0412	Dienelactone hydrolase
C5B74_09635	COG2207	Transcriptional regulator
C5B74_09645	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_09650	COG2610	gluconate transmembrane transporter activity
C5B74_09660	COG0583	DNA-binding transcription factor activity
C5B74_09670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5B74_09675	COG2031	fatty acid transporter
C5B74_09680	COG0183	Belongs to the thiolase family
C5B74_09685	COG0583	DNA-binding transcription factor activity
C5B74_09690	COG0583	DNA-binding transcription factor activity
C5B74_09705	COG1027	Aspartate ammonia-lyase
C5B74_09715	COG0477	Major facilitator Superfamily
C5B74_09735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5B74_09740	COG4521	taurine ABC transporter
C5B74_09765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5B74_09770	COG1733	regulation of RNA biosynthetic process
C5B74_09775	COG3708	Transcriptional regulator
C5B74_09775	COG2207	Transcriptional regulator
C5B74_09790	COG0730	response to heat
C5B74_09800	COG3453	Protein conserved in bacteria
C5B74_09800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5B74_09810	COG3781	membrane
C5B74_09815	COG1063	alcohol dehydrogenase
C5B74_09825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5B74_09830	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5B74_09835	COG0022	dehydrogenase e1 component
C5B74_09840	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C5B74_09845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5B74_09860	COG3706	GGDEF domain
C5B74_09875	COG0133	tryptophan synthase activity
C5B74_09885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C5B74_09920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5B74_09945	COG2226	methyltransferase
C5B74_10000	COG0842	Transport permease protein
C5B74_10005	COG0842	Transport permease protein
C5B74_10010	COG1131	(ABC) transporter
C5B74_10025	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5B74_10030	COG4773	Receptor
C5B74_10050	COG0730	response to heat
C5B74_10055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5B74_10075	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C5B74_10135	COG4264	IucA IucC family
C5B74_10140	COG4264	IucA IucC family
C5B74_10160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5B74_10175	COG1960	acyl-CoA dehydrogenase activity
C5B74_10180	COG1960	acyl-CoA dehydrogenase activity
C5B74_10185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5B74_10190	COG2207	Transcriptional regulator
C5B74_10195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5B74_10200	COG0776	regulation of translation
C5B74_10225	COG0822	iron-sulfur transferase activity
C5B74_10230	COG0316	Belongs to the HesB IscA family
C5B74_10260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5B74_10280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5B74_10285	COG0702	epimerase
C5B74_10320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5B74_10330	COG0339	signal peptide processing
C5B74_10380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C5B74_10385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C5B74_10415	COG0776	regulation of translation
C5B74_10435	COG0590	tRNA wobble adenosine to inosine editing
C5B74_10465	COG2165	general secretion pathway protein
C5B74_10480	COG0084	hydrolase, TatD family'
C5B74_10500	COG1663	tetraacyldisaccharide 4'-kinase activity
C5B74_10505	COG1132	(ABC) transporter
C5B74_10515	COG0811	peptide transport
C5B74_10520	COG1475	DNA binding
C5B74_10525	COG1192	Involved in chromosome partitioning
C5B74_10535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5B74_10550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5B74_10555	COG0191	fructose-bisphosphate aldolase activity
C5B74_10575	COG0424	maF-like protein
C5B74_10580	COG2850	peptidyl-arginine hydroxylation
C5B74_10590	COG0640	Transcriptional regulator
C5B74_10600	COG3619	membrane
C5B74_10605	COG3122	Protein conserved in bacteria
C5B74_10610	COG1132	(ABC) transporter
C5B74_10630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C5B74_10635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5B74_10645	COG0506	proline dehydrogenase activity
C5B74_10645	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5B74_10645	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5B74_10650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C5B74_10665	COG3698	Phosphodiester glycosidase
C5B74_10675	COG2353	YceI-like domain
C5B74_10685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5B74_10730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C5B74_10730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C5B74_10755	COG3539	Fimbrial protein
C5B74_10760	COG3121	Chaperone
C5B74_10790	COG0697	spore germination
C5B74_10800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C5B74_10810	COG0583	DNA-binding transcription factor activity
C5B74_10830	COG1309	transcriptional regulator
C5B74_10845	COG1522	sequence-specific DNA binding
C5B74_10855	COG1126	abc transporter atp-binding protein
C5B74_10860	COG0765	amino acid transport
C5B74_10865	COG0765	amino acid transport
C5B74_10895	COG1464	Belongs to the NlpA lipoprotein family
C5B74_10905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C5B74_10910	COG2011	ABC-type metal ion transport system permease component
C5B74_10915	COG0012	GTP binding
C5B74_10940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C5B74_10980	COG0386	Belongs to the glutathione peroxidase family
C5B74_10990	COG0436	Aminotransferase
C5B74_11030	COG3634	alkyl hydroperoxide reductase activity
C5B74_11045	COG0583	DNA-binding transcription factor activity
C5B74_11050	COG0798	PFAM Bile acid sodium symporter
C5B74_11055	COG0640	Transcriptional regulator
C5B74_11070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C5B74_11080	COG0583	DNA-binding transcription factor activity
C5B74_11090	COG1953	Uracil, thiamine, allantoin
C5B74_11100	COG2175	clavaminate synthase activity
C5B74_11105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5B74_11110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C5B74_11115	COG4521	taurine ABC transporter
C5B74_11125	COG0477	Major facilitator Superfamily
C5B74_11150	COG1271	oxidase subunit
C5B74_11155	COG1294	oxidase, subunit
C5B74_11165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5B74_11185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C5B74_11205	COG3052	prosthetic group binding
C5B74_11210	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C5B74_11220	COG2814	Major facilitator Superfamily
C5B74_11240	COG1346	cytolysis
C5B74_11250	COG0583	DNA-binding transcription factor activity
C5B74_11255	COG0625	glutathione transferase activity
C5B74_11260	COG0625	glutathione transferase activity
C5B74_11265	COG0583	DNA-binding transcription factor activity
C5B74_11280	COG1045	serine acetyltransferase
C5B74_11285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5B74_11290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5B74_11300	COG1280	lysine exporter protein (LysE YggA)
C5B74_11315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5B74_11320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5B74_11325	COG1126	abc transporter atp-binding protein
C5B74_11330	COG0765	amino acid transport
C5B74_11335	COG0765	amino acid transport
C5B74_11355	COG2205	protein histidine kinase activity
C5B74_11355	COG0784	Response regulator, receiver
C5B74_11375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5B74_11395	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_11440	COG0583	DNA-binding transcription factor activity
C5B74_11460	COG0318	PFAM AMP-dependent synthetase and ligase
C5B74_11465	COG1309	transcriptional regulator
C5B74_11470	COG1960	acyl-CoA dehydrogenase activity
C5B74_11475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5B74_11480	COG1024	Enoyl-CoA hydratase
C5B74_11495	COG0583	DNA-binding transcription factor activity
C5B74_11510	COG1960	acyl-CoA dehydrogenase activity
C5B74_11520	COG2814	Major facilitator Superfamily
C5B74_11530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C5B74_11535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C5B74_11540	COG2814	Major facilitator Superfamily
C5B74_11545	COG1960	acyl-CoA dehydrogenase activity
C5B74_11550	COG1024	Enoyl-CoA hydratase
C5B74_11555	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_11560	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5B74_11565	COG0183	Belongs to the thiolase family
C5B74_11575	COG2814	Major facilitator Superfamily
C5B74_11585	COG1024	Enoyl-CoA hydratase
C5B74_11600	COG1960	acyl-CoA dehydrogenase activity
C5B74_11605	COG2814	Major facilitator Superfamily
C5B74_11610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5B74_11615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C5B74_11630	COG3842	ATPase activity
C5B74_11635	COG1840	ABC-type Fe3 transport system, periplasmic component
C5B74_11645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5B74_11650	COG1414	Transcriptional regulator
C5B74_11660	COG0583	DNA-binding transcription factor activity
C5B74_11665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5B74_11670	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_11680	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C5B74_11690	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_11695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5B74_11700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_11705	COG2267	carboxylic ester hydrolase activity
C5B74_11725	COG3038	cytochrome b561
C5B74_11730	COG0753	catalase activity
C5B74_11770	COG2050	protein possibly involved in aromatic compounds catabolism
C5B74_11780	COG3327	negative regulation of DNA-templated transcription, initiation
C5B74_11785	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C5B74_11790	COG0183	Belongs to the thiolase family
C5B74_11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5B74_11800	COG1024	Enoyl-CoA hydratase
C5B74_11805	COG1024	Enoyl-CoA hydratase
C5B74_11810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5B74_11815	COG2151	metal-sulfur cluster biosynthetic enzyme
C5B74_11820	COG3396	Phenylacetate-CoA oxygenase
C5B74_11825	COG3460	Phenylacetate-CoA oxygenase
C5B74_11830	COG3396	Phenylacetate-CoA oxygenase
C5B74_11835	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_11835	COG2030	dehydratase
C5B74_11840	COG1760	l-serine dehydratase
C5B74_11845	COG0531	amino acid
C5B74_11850	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_11865	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5B74_11875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5B74_11895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5B74_11910	COG0789	Transcriptional regulator
C5B74_11925	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C5B74_11940	COG2807	transmembrane transport
C5B74_11945	COG0590	tRNA wobble adenosine to inosine editing
C5B74_11955	COG0583	DNA-binding transcription factor activity
C5B74_11995	COG2885	chlorophyll binding
C5B74_11995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C5B74_12065	COG1116	anion transmembrane transporter activity
C5B74_12070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5B74_12080	COG0864	Transcriptional regulator
C5B74_12100	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5B74_12105	COG0439	Biotin carboxylase
C5B74_12120	COG1063	alcohol dehydrogenase
C5B74_12130	COG1309	transcriptional regulator
C5B74_12155	COG0038	chloride channel
C5B74_12160	COG4770	biotin carboxylase activity
C5B74_12180	COG1914	H( )-stimulated, divalent metal cation uptake system
C5B74_12185	COG0583	DNA-binding transcription factor activity
C5B74_12200	COG3209	COG3209 Rhs family protein
C5B74_12205	COG3501	Rhs element vgr protein
C5B74_12240	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5B74_12260	COG2814	Major facilitator Superfamily
C5B74_12270	COG1560	Kdo2-lipid A biosynthetic process
C5B74_12280	COG5006	permease, DMT superfamily
C5B74_12285	COG1522	sequence-specific DNA binding
C5B74_12300	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C5B74_12340	COG1538	Outer membrane efflux protein
C5B74_12345	COG1137	ATPase activity
C5B74_12350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C5B74_12360	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C5B74_12365	COG0517	IMP dehydrogenase activity
C5B74_12365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5B74_12400	COG1733	regulation of RNA biosynthetic process
C5B74_12405	COG2814	Major facilitator Superfamily
C5B74_12445	COG1278	Cold shock
C5B74_12450	COG1280	lysine exporter protein (LysE YggA)
C5B74_12485	COG1570	exodeoxyribonuclease VII activity
C5B74_12540	COG0583	DNA-binding transcription factor activity
C5B74_12545	COG4638	Rieske (2fe-2S)
C5B74_12550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C5B74_12555	COG0543	2 iron, 2 sulfur cluster binding
C5B74_12555	COG0633	Ferredoxin
C5B74_12560	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_12565	COG3135	benzoate transporter
C5B74_12570	COG2814	Major facilitator Superfamily
C5B74_12585	COG1643	Atp-dependent helicase
C5B74_12590	COG0450	alkyl hydroperoxide reductase
C5B74_12600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C5B74_12610	COG3634	alkyl hydroperoxide reductase activity
C5B74_12630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5B74_12635	COG0625	glutathione transferase activity
C5B74_12645	COG2885	chlorophyll binding
C5B74_12695	COG1765	OsmC-like protein
C5B74_12705	COG0667	Aldo Keto reductase
C5B74_12720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C5B74_12730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5B74_12750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5B74_12760	COG3038	cytochrome b561
C5B74_12765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C5B74_12770	COG2252	PERMEase
C5B74_12780	COG2072	flavoprotein involved in K transport
C5B74_12795	COG3316	Transposase and inactivated derivatives
C5B74_12805	COG1309	transcriptional regulator
C5B74_12815	COG0300	oxidoreductase activity
C5B74_12825	COG3316	Transposase and inactivated derivatives
C5B74_12835	COG3316	Transposase and inactivated derivatives
C5B74_12920	COG3316	Transposase and inactivated derivatives
C5B74_12940	COG3316	Transposase and inactivated derivatives
C5B74_12945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C5B74_12955	COG3316	Transposase and inactivated derivatives
C5B74_12980	COG3316	Transposase and inactivated derivatives
C5B74_12985	COG1113	amino acid transport
C5B74_13005	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_13025	COG0531	amino acid
C5B74_13035	COG1113	amino acid transport
C5B74_13080	COG3209	COG3209 Rhs family protein
C5B74_13085	COG3501	Rhs element vgr protein
C5B74_13105	COG4269	membrane
C5B74_13120	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5B74_13120	COG1902	pentaerythritol trinitrate reductase activity
C5B74_13130	COG3706	GGDEF domain
C5B74_13130	COG5001	Diguanylate cyclase
C5B74_13130	COG2203	Gaf domain
C5B74_13130	COG4251	negative regulation of phosphorylation
C5B74_13140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5B74_13160	COG4172	Belongs to the ABC transporter superfamily
C5B74_13165	COG4239	(ABC) transporter, permease
C5B74_13170	COG4174	ABC transporter (Permease)
C5B74_13180	COG0741	lytic transglycosylase activity
C5B74_13180	COG1388	LysM domain
C5B74_13180	COG0741	lytic transglycosylase activity
C5B74_13180	COG1388	LysM domain
C5B74_13185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5B74_13225	COG0583	DNA-binding transcription factor activity
C5B74_13230	COG1279	arginine transmembrane transporter activity
C5B74_13250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5B74_13255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5B74_13260	COG0006	proline dipeptidase activity
C5B74_13295	COG2194	sulfuric ester hydrolase activity
C5B74_13340	COG0739	heme binding
C5B74_13665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C5B74_13690	COG3384	dioxygenase
C5B74_13700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5B74_13705	COG2878	Part of a membrane complex involved in electron transport
C5B74_13710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5B74_13735	COG0768	penicillin binding
C5B74_13740	COG0742	ribosomal rna small subunit methyltransferase
C5B74_13755	COG0830	nickel cation binding
C5B74_13765	COG0804	urea catabolic process
C5B74_13805	COG1253	flavin adenine dinucleotide binding
C5B74_13815	COG2851	Citrate transporter
C5B74_13865	COG1773	rubredoxin
C5B74_13870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5B74_13880	COG0583	DNA-binding transcription factor activity
C5B74_13905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C5B74_13910	COG4181	ATPase activity
C5B74_13955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C5B74_13975	COG0306	phosphate transporter
C5B74_13985	COG3958	Transketolase
C5B74_13990	COG3959	Transketolase, thiamine diphosphate binding domain
C5B74_13995	COG2271	Major facilitator Superfamily
C5B74_14000	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_14005	COG0583	DNA-binding transcription factor activity
C5B74_14025	COG2223	nitrite transmembrane transporter activity
C5B74_14030	COG2207	Transcriptional regulator
C5B74_14035	COG2066	Belongs to the glutaminase family
C5B74_14040	COG0242	peptide deformylase activity
C5B74_14045	COG0477	Major facilitator Superfamily
C5B74_14055	COG0028	Belongs to the TPP enzyme family
C5B74_14070	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_14075	COG2267	carboxylic ester hydrolase activity
C5B74_14085	COG2271	Major facilitator Superfamily
C5B74_14090	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5B74_14100	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_14120	COG1414	Transcriptional regulator
C5B74_14135	COG1024	Enoyl-CoA hydratase
C5B74_14145	COG1215	transferase activity, transferring glycosyl groups
C5B74_14150	COG0726	polysaccharide deacetylase
C5B74_14150	COG1649	PFAM Uncharacterised BCR, COG1649
C5B74_14160	COG4681	YaeQ
C5B74_14170	COG0523	cobalamin synthesis protein
C5B74_14180	COG1607	acyl-coa hydrolase
C5B74_14190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5B74_14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C5B74_14200	COG1309	transcriptional regulator
C5B74_14225	COG2040	homocysteine
C5B74_14230	COG0531	amino acid
C5B74_14255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5B74_14260	COG0477	Major facilitator Superfamily
C5B74_14320	COG0405	Gamma-glutamyltransferase
C5B74_14325	COG2814	Major facilitator Superfamily
C5B74_14335	COG2050	protein possibly involved in aromatic compounds catabolism
C5B74_14350	COG1090	epimerase
C5B74_14370	COG0420	3'-5' exonuclease activity
C5B74_14395	COG0735	belongs to the Fur family
C5B74_14400	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5B74_14425	COG0121	glutamine amidotransferase
C5B74_14440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5B74_14450	COG0210	DNA helicase
C5B74_14455	COG2885	chlorophyll binding
C5B74_14460	COG0204	Acyl-transferase
C5B74_14475	COG2894	cell division
C5B74_14495	COG1280	lysine exporter protein (LysE YggA)
C5B74_14500	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5B74_14500	COG1674	ftsk spoiiie
C5B74_14505	COG0492	ferredoxin-NADP+ reductase activity
C5B74_14510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C5B74_14520	COG0456	acetyltransferase
C5B74_14580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5B74_14580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C5B74_14600	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_14620	COG0473	3-isopropylmalate dehydrogenase activity
C5B74_14625	COG0583	DNA-binding transcription factor activity
C5B74_14645	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5B74_14670	COG0564	pseudouridine synthase activity
C5B74_14680	COG0358	DNA primase activity
C5B74_14695	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C5B74_14725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5B74_14755	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5B74_14765	COG0352	thiamine-phosphate diphosphorylase activity
C5B74_14765	COG0351	phosphomethylpyrimidine kinase
C5B74_14765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C5B74_14770	COG1652	LysM domain
C5B74_14795	COG1399	metal-binding, possibly nucleic acid-binding protein
C5B74_14800	COG3101	peptidyl-lysine hydroxylation
C5B74_14805	COG0009	L-threonylcarbamoyladenylate synthase
C5B74_14810	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C5B74_14815	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5B74_14830	COG4106	trans-aconitate 2-methyltransferase activity
C5B74_14845	COG2226	methyltransferase
C5B74_14845	COG0596	Alpha beta hydrolase
C5B74_14845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5B74_14850	COG1877	trehalose-phosphatase activity
C5B74_14855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C5B74_14860	COG2223	nitrite transmembrane transporter activity
C5B74_14880	COG1196	nuclear chromosome segregation
C5B74_14890	COG0730	response to heat
C5B74_14905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5B74_14915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5B74_14975	COG0489	protein tyrosine kinase activity
C5B74_14985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5B74_14985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5B74_15015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C5B74_15020	COG2081	HI0933 family
C5B74_15030	COG0668	transmembrane transport
C5B74_15050	COG0583	DNA-binding transcription factor activity
C5B74_15070	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5B74_15075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C5B74_15105	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C5B74_15140	COG2205	protein histidine kinase activity
C5B74_15145	COG0745	RESPONSE REGULATOR receiver
C5B74_15165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5B74_15175	COG2205	protein histidine kinase activity
C5B74_15255	COG4993	Dehydrogenase
C5B74_15275	COG0384	phenazine biosynthesis protein PhzF
C5B74_15305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C5B74_15310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5B74_15320	COG0583	DNA-binding transcription factor activity
C5B74_15340	COG1473	amidohydrolase
C5B74_15350	COG0583	DNA-binding transcription factor activity
C5B74_15370	COG0583	DNA-binding transcription factor activity
C5B74_15375	COG1053	succinate dehydrogenase
C5B74_15385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C5B74_15390	COG2814	Major facilitator Superfamily
C5B74_15395	COG1960	acyl-CoA dehydrogenase activity
C5B74_15400	COG0583	DNA-binding transcription factor activity
C5B74_15405	COG1063	alcohol dehydrogenase
C5B74_15435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C5B74_15440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C5B74_15445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5B74_15460	COG3667	copper resistance
C5B74_15465	COG2132	Multicopper oxidase
C5B74_15475	COG0561	phosphatase activity
C5B74_15480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5B74_15505	COG1214	PFAM Peptidase M22, glycoprotease
C5B74_15555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5B74_15565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5B74_15570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C5B74_15575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5B74_15635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5B74_15645	COG1846	Transcriptional regulator
C5B74_15650	COG1764	response to oxidative stress
C5B74_15690	COG0037	tRNA processing
C5B74_15700	COG0248	Ppx GppA phosphatase
C5B74_15730	COG0072	phenylalanine-tRNA ligase activity
C5B74_15755	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5B74_15770	COG1238	metal cluster binding
C5B74_15775	COG0625	glutathione transferase activity
C5B74_15795	COG0318	PFAM AMP-dependent synthetase and ligase
C5B74_15800	COG3028	Belongs to the UPF0307 family
C5B74_15805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5B74_15825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5B74_15830	COG0617	tRNA 3'-terminal CCA addition
C5B74_15835	COG1555	photosystem II stabilization
C5B74_15840	COG3956	TIGRFAM MazG family protein
C5B74_15850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5B74_15870	COG5002	protein histidine kinase activity
C5B74_15870	COG2205	protein histidine kinase activity
C5B74_15870	COG0784	Response regulator, receiver
C5B74_15875	COG1024	Enoyl-CoA hydratase
C5B74_15880	COG2084	Dehydrogenase
C5B74_15885	COG3622	Belongs to the hyi family
C5B74_15900	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C5B74_15905	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C5B74_15910	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C5B74_15915	COG0697	spore germination
C5B74_15925	COG2814	Major facilitator Superfamily
C5B74_15930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5B74_15940	COG0583	DNA-binding transcription factor activity
C5B74_15950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5B74_15965	COG0084	hydrolase, TatD family'
C5B74_15980	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C5B74_16015	COG0440	acetolactate synthase activity
C5B74_16020	COG0028	Belongs to the TPP enzyme family
C5B74_16045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5B74_16050	COG0577	efflux transmembrane transporter activity
C5B74_16050	COG1136	(ABC) transporter
C5B74_16055	COG1538	Outer membrane efflux protein
C5B74_16070	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C5B74_16075	COG1162	GTPase activity
C5B74_16085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5B74_16105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5B74_16110	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_16150	COG2986	histidine ammonia-lyase
C5B74_16165	COG0318	PFAM AMP-dependent synthetase and ligase
C5B74_16175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5B74_16180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5B74_16220	COG1426	Protein conserved in bacteria
C5B74_16255	COG0793	Belongs to the peptidase S41A family
C5B74_16270	COG2267	carboxylic ester hydrolase activity
C5B74_16280	COG1012	belongs to the aldehyde dehydrogenase family
C5B74_16285	COG3265	gluconokinase activity
C5B74_16295	COG0800	Aldolase
C5B74_16305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C5B74_16310	COG0280	phosphate acetyltransferase
C5B74_16310	COG0857	belongs to the CobB CobQ family
C5B74_16315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C5B74_16315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C5B74_16335	COG0740	serine-type endopeptidase activity
C5B74_16345	COG4774	siderophore transport
C5B74_16355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5B74_16365	COG2813	Specifically methylates the guanine in position
C5B74_16365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C5B74_16465	COG0788	formyltetrahydrofolate deformylase activity
C5B74_16480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5B74_16485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5B74_16490	COG4651	solute:proton antiporter activity
C5B74_16490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5B74_16510	COG0724	RNA recognition motif
C5B74_16515	COG0210	DNA helicase
C5B74_16540	COG1733	regulation of RNA biosynthetic process
C5B74_16560	COG1280	lysine exporter protein (LysE YggA)
C5B74_16565	COG1560	Kdo2-lipid A biosynthetic process
C5B74_16575	COG1301	dicarboxylic acid transport
C5B74_16630	COG0473	3-isopropylmalate dehydrogenase activity
C5B74_16695	COG0583	DNA-binding transcription factor activity
C5B74_16705	COG0625	glutathione transferase activity
C5B74_16710	COG2378	regulation of single-species biofilm formation
C5B74_16715	COG0546	phosphoglycolate phosphatase activity
C5B74_16730	COG1530	ribonuclease E activity
C5B74_16750	COG0583	DNA-binding transcription factor activity
C5B74_16755	COG4221	oxidoreductase activity
C5B74_16760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5B74_16770	COG0534	Mate efflux family protein
C5B74_16785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C5B74_16825	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C5B74_16830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5B74_16845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5B74_16855	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C5B74_16855	COG0644	oxidoreductase
C5B74_16860	COG0425	Belongs to the sulfur carrier protein TusA family
C5B74_16865	COG4535	Mg2 and Co2 transporter CorC
C5B74_16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5B74_16895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5B74_16900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5B74_16900	COG0475	glutathione-regulated potassium exporter activity
C5B74_16905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5B74_16915	COG0484	heat shock protein binding
C5B74_16920	COG0789	Transcriptional regulator
C5B74_16925	COG0598	Magnesium transport protein CorA
C5B74_16945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5B74_16950	COG1074	ATP-dependent DNA helicase activity
C5B74_16955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C5B74_16985	COG2226	methyltransferase
C5B74_17000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5B74_17005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5B74_17020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C5B74_17020	COG2111	Na H antiporter
C5B74_17025	COG1006	Multisubunit Na H antiporter MnhC subunit
C5B74_17030	COG0651	ATP synthesis coupled electron transport
C5B74_17040	COG2212	antiporter activity
C5B74_17060	COG0195	Participates in both transcription termination and antitermination
C5B74_17110	COG0237	dephospho-CoA kinase activity
C5B74_17120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5B74_17135	COG0497	DNA recombination
C5B74_17145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C5B74_17175	COG2169	Transcriptional regulator
C5B74_17175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5B74_17180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5B74_17250	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C5B74_17265	COG0326	Molecular chaperone. Has ATPase activity
C5B74_17280	COG2056	Na+-H+ antiporter family
C5B74_17285	COG0596	Alpha beta hydrolase
C5B74_17380	COG0546	phosphoglycolate phosphatase activity
C5B74_17385	COG1716	ATPase activity
C5B74_17430	COG0181	hydroxymethylbilane synthase activity
C5B74_17440	COG3275	phosphorelay sensor kinase activity
C5B74_17460	COG1538	Outer membrane efflux protein
C5B74_17465	COG0697	spore germination
C5B74_17490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C5B74_17495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5B74_17500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5B74_17505	COG0772	Belongs to the SEDS family
C5B74_17530	COG4974	Belongs to the 'phage' integrase family
C5B74_17535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5B74_17545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5B74_17555	COG2197	response regulator
C5B74_17570	COG0793	Belongs to the peptidase S41A family
C5B74_17575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C5B74_17580	COG0795	lipopolysaccharide-transporting ATPase activity
C5B74_17620	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5B74_17620	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5B74_17630	COG0004	ammonium transporteR
C5B74_17635	COG0347	Belongs to the P(II) protein family
C5B74_17645	COG0606	chelatase, subunit chli
C5B74_17700	COG0659	secondary active sulfate transmembrane transporter activity
C5B74_17705	COG0589	response to stress
C5B74_17755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5B74_17810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C5B74_17840	COG0659	secondary active sulfate transmembrane transporter activity
C5B74_17845	COG0589	response to stress
C5B74_17875	COG0606	chelatase, subunit chli
C5B74_17880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5B74_17890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5B74_17905	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C5B74_17920	COG0318	PFAM AMP-dependent synthetase and ligase
C5B74_17930	COG0477	Major facilitator Superfamily
C5B74_17935	COG2860	membrane
C5B74_17945	COG1253	flavin adenine dinucleotide binding
C5B74_17965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5B74_18000	COG0655	NAD(P)H dehydrogenase (quinone) activity
C5B74_18010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5B74_18045	COG1309	transcriptional regulator
C5B74_18080	COG0758	DNA mediated transformation
C5B74_18090	COG0697	spore germination
C5B74_18095	COG1309	transcriptional regulator
C5B74_18110	COG0386	Belongs to the glutathione peroxidase family
C5B74_18175	COG1121	(ABC) transporter
C5B74_18180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5B74_18185	COG1280	lysine exporter protein (LysE YggA)
C5B74_18190	COG2837	iron assimilation
C5B74_18200	COG0281	malic enzyme
C5B74_18245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5B74_18245	COG0519	Catalyzes the synthesis of GMP from XMP
C5B74_18250	COG4399	Belongs to the UPF0754 family
C5B74_18255	COG2259	Doxx family
C5B74_18260	COG0586	Pfam SNARE associated Golgi protein
C5B74_18275	COG1192	Involved in chromosome partitioning
C5B74_18285	COG0271	Belongs to the BolA IbaG family
C5B74_18305	COG2267	carboxylic ester hydrolase activity
C5B74_18325	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_18325	COG0318	PFAM AMP-dependent synthetase and ligase
C5B74_18325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5B74_18325	COG3321	synthase
C5B74_18325	COG0300	oxidoreductase activity
C5B74_18330	COG1960	acyl-CoA dehydrogenase activity
C5B74_18340	COG2197	response regulator
C5B74_18350	COG3916	Acyl-homoserine-lactone synthase
C5B74_18355	COG0477	Major facilitator Superfamily
C5B74_18360	COG1024	Enoyl-CoA hydratase
C5B74_18365	COG1024	Enoyl-CoA hydratase
C5B74_18370	COG1960	acyl-CoA dehydrogenase activity
C5B74_18375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5B74_18395	COG1113	amino acid transport
C5B74_18400	COG1113	amino acid transport
C5B74_18405	COG0251	oxidation-reduction process
C5B74_18420	COG1522	sequence-specific DNA binding
C5B74_18445	COG0564	pseudouridine synthase activity
C5B74_18510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C5B74_18525	COG1802	Transcriptional regulator
C5B74_18535	COG1448	Aminotransferase
C5B74_18540	COG0277	FAD linked oxidase domain protein
C5B74_18550	COG2186	Transcriptional regulator
C5B74_18560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5B74_18565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5B74_18580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5B74_18590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5B74_18600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5B74_18605	COG0438	transferase activity, transferring glycosyl groups
C5B74_18625	COG1216	Glycosyl transferase, family 2
C5B74_18630	COG5039	Polysaccharide pyruvyl transferase
C5B74_18640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C5B74_18645	COG1596	polysaccharide export
C5B74_18670	COG0728	peptidoglycan biosynthetic process
C5B74_18675	COG3023	N-Acetylmuramoyl-L-alanine amidase
C5B74_18735	COG0546	phosphoglycolate phosphatase activity
C5B74_18740	COG1028	Short-chain dehydrogenase reductase Sdr
C5B74_18760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5B74_18765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C5B74_18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5B74_18775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C5B74_18780	COG1116	anion transmembrane transporter activity
C5B74_18785	COG1309	transcriptional regulator
C5B74_18790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5B74_18800	COG0196	riboflavin kinase activity
C5B74_18805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5B74_18815	COG1047	Peptidyl-prolyl cis-trans
C5B74_18855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5B74_18910	COG2951	lytic endotransglycosylase activity
C5B74_18915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5B74_18935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5B74_18945	COG0671	phosphoesterase, PA-phosphatase related
C5B74_18950	COG0861	Integral membrane protein TerC family
C5B74_18960	COG0754	glutathionylspermidine amidase activity
C5B74_18970	COG0402	S-adenosylhomocysteine deaminase activity
C5B74_18985	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5B74_18990	COG1230	cation diffusion facilitator family transporter
C5B74_19005	COG0706	membrane insertase activity
C5B74_19020	COG0230	Belongs to the bacterial ribosomal protein bL34 family