locus-tag class description B7L35_00080 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) B7L35_00100 ENOG4107RZZ dna polymerase iii epsilon subunit B7L35_00125 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD B7L35_00135 ENOG4105DEN Luciferase family B7L35_00155 ENOG4105CC0 LysR family Transcriptional regulator B7L35_00170 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) B7L35_00185 ENOG4105C1G acyl-Coa dehydrogenase B7L35_00195 ENOG4108MEJ flavin reductase domain protein B7L35_00200 ENOG4105D06 uba thif-type nad fad binding protein B7L35_00220 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) B7L35_00225 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) B7L35_00230 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) B7L35_00235 ENOG4105C08 Histidine kinase B7L35_00240 ENOG4105EEX Two component transcriptional regulator (Winged helix family B7L35_00245 ENOG4105CFQ glutamine synthetase B7L35_00260 ENOG4107S74 Lysophospholipid transporter LplT B7L35_00265 ENOG4105CFU surface antigen B7L35_00285 ENOG4107QIJ Aconitate hydratase 2 B7L35_00295 ENOG4105EYW Ion transport protein B7L35_00300 ENOG4105F27 Major Facilitator B7L35_00315 ENOG4105DZ2 Transcriptional regulator B7L35_00350 ENOG4105K8N protein family UPF0079, ATPase B7L35_00355 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) B7L35_00365 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) B7L35_00370 ENOG4108TZV Membrane B7L35_00375 ENOG4108RCM Nitroreductase B7L35_00385 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) B7L35_00400 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) B7L35_00405 ENOG4107FQ9 ethanolamine ammonia-lyase B7L35_00410 ENOG4105CPD ethanolamine ammonia-lyase B7L35_00415 ENOG4107R55 ethanolamine transporter B7L35_00425 ENOG4107RR1 TRANSCRIPTIONal B7L35_00435 ENOG4105C0A alcohol dehydrogenase B7L35_00440 ENOG4107QUV Domain protein B7L35_00465 ENOG4105CD8 aminopeptidase N B7L35_00480 ENOG4108D1K outer membrane usher protein B7L35_00505 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) B7L35_00510 ENOG4105EW9 transcriptional regulator AsnC family B7L35_00525 ENOG4105R8C Transcriptional regulator B7L35_00535 ENOG4105CUY Mechanosensitive ion channel B7L35_00565 ENOG4105CNM Receptor B7L35_00580 ENOG4105C5H ABC transporter B7L35_00585 ENOG41081QV Universal stress protein B7L35_00600 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic B7L35_00605 ENOG4105D5G Transposase B7L35_00620 ENOG4105DKK Benzoate B7L35_00625 ENOG4105EW9 transcriptional regulator AsnC family B7L35_00630 ENOG4108NIW Leucine export protein LeuE B7L35_00635 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) B7L35_00640 ENOG4105CC0 LysR family Transcriptional regulator B7L35_00650 ENOG4105CHU acetyl-coa acetyltransferase B7L35_00655 ENOG4105CHR reductase B7L35_00690 ENOG4107QMP dna polymerase iii subunits gamma and tau B7L35_00695 ENOG4105HSS phospholipase C B7L35_00705 ENOG4105C0A alcohol dehydrogenase B7L35_00745 ENOG4105CBC glutamate synthase B7L35_01095 ENOG4105DIJ Phosphoethanolamine transferase B7L35_01105 ENOG4105D8G Major Facilitator superfamily B7L35_01115 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase B7L35_01120 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein B7L35_01140 ENOG4105CK6 Two component transcriptional regulator (Winged helix family B7L35_01150 ENOG4107QZF nitrite reductase NADPH large subunit B7L35_01155 ENOG4108IFG nitrite reductase, (NAD(P)H) B7L35_01175 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) B7L35_01190 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) B7L35_01195 ENOG4105CVM Molybdenum cofactor synthesis domain protein B7L35_01205 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7L35_01210 ENOG4105T38 integral membrane protein B7L35_01230 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) B7L35_01235 ENOG4105CMR udp-glucose 4-epimerase B7L35_01295 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7L35_01300 ENOG4105CUX Signal transduction histidine kinase B7L35_01320 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) B7L35_01325 ENOG4105KNE Phosphatidate cytidylyltransferase B7L35_01335 ENOG4105DZP Membrane-associated zinc metalloprotease B7L35_01340 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane B7L35_01360 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) B7L35_01375 ENOG4105Y3E Modulates RecA activity (By similarity) B7L35_01385 ENOG4105VEJ Heat shock protein B7L35_01390 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 B7L35_01415 ENOG4105F7P transcriptional regulator AsnC family B7L35_01425 ENOG4105C85 amino acid B7L35_01440 ENOG4105CHH sulfate transporter B7L35_01445 ENOG4108RAV Conserved protein B7L35_01450 ENOG4105D8V Glucose sorbosone dehydrogenase B7L35_01465 ENOG4105D5G Transposase B7L35_01485 ENOG4105DM4 PTS System B7L35_01490 ENOG4105DE4 1-phosphofructokinase B7L35_01495 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) B7L35_01520 ENOG4105CWM branched-chain amino acid transport system II carrier protein B7L35_01525 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) B7L35_01530 ENOG4105CC0 LysR family Transcriptional regulator B7L35_01540 ENOG4105M2J Glutaredoxin B7L35_01545 ENOG4105C8Y Acetylornithine aminotransferase B7L35_01550 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) B7L35_01580 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) B7L35_01590 ENOG41068P6 UPF0319 protein B7L35_01610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii B7L35_01615 ENOG4105C4M (Ubiquinol oxidase) subunit I B7L35_01630 ENOG4105PV3 Inner membrane protein yqiJ B7L35_01645 ENOG4105E0K tonB-dependent siderophore receptor B7L35_01655 ENOG4105HDD phospholipase B7L35_01660 ENOG4105CZN Potassium uptake protein B7L35_01670 ENOG4105C7B Threonine dehydratase B7L35_01700 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) B7L35_01705 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit B7L35_01715 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) B7L35_01730 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_01775 ENOG4107VMU Membrane B7L35_01780 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) B7L35_01790 ENOG4107QP7 CoA-transferase subunit A B7L35_01795 ENOG4107QNJ CoA-transferase subunit B B7L35_01800 ENOG4105CHU acetyl-coa acetyltransferase B7L35_01805 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase B7L35_01810 ENOG4105F2Z 3-oxoadipate enol-lactonase B7L35_01815 ENOG4105D2S major facilitator superfamily B7L35_01820 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase B7L35_01825 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta B7L35_01830 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha B7L35_01835 ENOG4105FF2 Type I DHQase B7L35_01840 ENOG4106JPM 3-dehydroshikimate dehydratase B7L35_01845 ENOG4105TW1 Carbohydrate-selective porin OprB B7L35_01850 ENOG4105DZG Dehydrogenase B7L35_01860 ENOG4105MD1 YeeE YedE family protein B7L35_01875 ENOG4107HP6 Transcriptional regulator B7L35_01880 ENOG4108PTX LysR family Transcriptional regulator B7L35_01885 ENOG4105C1G acyl-Coa dehydrogenase B7L35_01910 ENOG4105DNH Major Facilitator B7L35_01920 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) B7L35_01940 ENOG4105FUY alpha subunit B7L35_01950 ENOG4105CHR reductase B7L35_01970 ENOG4105F11 amine oxidase B7L35_01980 ENOG4105C26 Dehydrogenase B7L35_01990 ENOG4105F2Z 3-oxoadipate enol-lactonase B7L35_01995 ENOG4105CHU acetyl-coa acetyltransferase B7L35_02000 ENOG4107QNJ CoA-transferase subunit B B7L35_02005 ENOG4107QP7 CoA-transferase subunit A B7L35_02015 ENOG4105NN7 muconolactone delta-isomerase B7L35_02020 ENOG4105DTQ mandelate racemase muconate lactonizing B7L35_02025 ENOG4108KB2 LysR family Transcriptional regulator B7L35_02035 ENOG4107EJG GntR family transcriptional regulator B7L35_02055 ENOG4105CZJ Aldehyde dehydrogenase B7L35_02070 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_02110 ENOG4107Z3H Transcriptional regulator, TetR family B7L35_02115 ENOG4108PTX LysR family Transcriptional regulator B7L35_02120 ENOG41061TZ Short-chain dehydrogenase reductase Sdr B7L35_02125 ENOG41061TZ Short-chain dehydrogenase reductase Sdr B7L35_02130 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr B7L35_02140 ENOG4105CSU acyl-Coa dehydrogenase B7L35_02150 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_02195 ENOG4105FDP GntR family transcriptional regulator B7L35_02210 ENOG4106KR7 LysR family Transcriptional regulator B7L35_02230 ENOG4105DUY Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein B7L35_02240 ENOG4105EHG Permease protein B7L35_02245 ENOG4105E0A ABC, transporter B7L35_02265 ENOG4105C5T Phosphoribosyl pyrophosphate synthase B7L35_02315 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) B7L35_02360 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7L35_02370 ENOG4105CT3 Monooxygenase B7L35_02440 ENOG4105X0I Fimbrial B7L35_02490 ENOG4107RZC phospholipase d B7L35_02505 ENOG4108IGT Dipeptidase B7L35_02540 ENOG4107T31 5'-nucleotidase B7L35_02550 ENOG4105WQI isochorismatase B7L35_02555 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase B7L35_02560 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) B7L35_02565 ENOG4105E0C molybdate abc transporter B7L35_02570 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein B7L35_02575 ENOG4105F4R Transcriptional regulator mode B7L35_02580 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit B7L35_02585 ENOG4108YS2 small subunit B7L35_02590 ENOG4105F57 Anthranilate dioxygenase reductase B7L35_02615 ENOG4105CHR reductase B7L35_02625 ENOG4105D2S major facilitator superfamily B7L35_02630 ENOG4105CF7 AraC family transcriptional regulator B7L35_02635 ENOG4105DTD Dehydrogenase B7L35_02640 ENOG4105CY2 Citrate transporter B7L35_02650 ENOG4108M0I Transcriptional regulator B7L35_02665 ENOG4105CRW Short chain fatty acid transporter B7L35_02670 ENOG4105CHU acetyl-coa acetyltransferase B7L35_02680 ENOG4107YNJ LysR family Transcriptional regulator B7L35_02695 ENOG4108IJ0 Aspartate ammonia-lyase B7L35_02705 ENOG4105CSH Transporter B7L35_02725 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component B7L35_02730 ENOG4106FTQ Taurine ABC transporter, periplasmic B7L35_02745 ENOG4105FDP GntR family transcriptional regulator B7L35_02755 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) B7L35_02760 ENOG4105KVH Transcriptional regulator B7L35_02765 ENOG4105UEI Transcriptional Regulator AraC Family B7L35_02780 ENOG4108VCT Sulfite exporter TauE/SafE B7L35_02790 ENOG4107S76 domain protein B7L35_02800 ENOG4105FFC UPF0187 protein B7L35_02810 ENOG4105CHR reductase B7L35_02825 ENOG4105CPP Dehydrogenase, E1 component B7L35_02830 ENOG4107R0V Pyruvate dehydrogenase B7L35_02835 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) B7L35_02850 ENOG4105BZU Histidine kinase B7L35_02860 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) B7L35_02865 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) B7L35_02905 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) B7L35_02920 ENOG4105C28 cystathionine B7L35_02930 ENOG4105F2W methyltransferase B7L35_02960 ENOG4105K59 histidine triad (HIT) protein B7L35_02985 ENOG4107QWP ABC-2 type transporter B7L35_02990 ENOG4107QWP ABC-2 type transporter B7L35_02995 ENOG4105CJ1 ABC, transporter B7L35_03010 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) B7L35_03015 ENOG4105CNM Receptor B7L35_03035 ENOG4107TSN permease B7L35_03040 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) B7L35_03055 ENOG4107TB6 phosphoglycerate mutase B7L35_03060 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) B7L35_03065 ENOG4108YZT Adenosylcobinamide kinase B7L35_03075 ENOG4107VXZ Hydrolase B7L35_03110 ENOG4105JSC dimethylmenaquinone methyltransferase B7L35_03120 ENOG4105DJU Siderophore biosynthesis protein B7L35_03125 ENOG4105DUU IucA IucC family protein B7L35_03130 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7L35_03145 ENOG4108Z66 YbaK ebsC protein B7L35_03160 ENOG4105C1G acyl-Coa dehydrogenase B7L35_03165 ENOG4105C1G acyl-Coa dehydrogenase B7L35_03170 ENOG4105EEF Alkane 1-monooxygenase B7L35_03175 ENOG4105E7U AraC family transcriptional regulator B7L35_03180 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) B7L35_03185 ENOG4105K70 DNA-binding protein B7L35_03200 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family B7L35_03210 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins B7L35_03215 ENOG4108Z4V iron-sulfur cluster assembly B7L35_03230 ENOG4108ZIT Ferredoxin, 2FE-2S B7L35_03235 ENOG4105F8J Adenylate Guanylate cyclase B7L35_03245 ENOG4108JA2 transcriptioN-repair coupling factor B7L35_03250 ENOG4105D5G Transposase B7L35_03260 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) B7L35_03265 ENOG4105K4T epimerase B7L35_03280 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase B7L35_03310 ENOG4105DGW oligopeptidase A B7L35_03315 ENOG4107QSI ABC, transporter B7L35_03345 ENOG4105SG9 biopolymer transport protein, ExbD B7L35_03355 ENOG4107QP3 malate synthase g B7L35_03360 ENOG4105D6Z AFG1 family ATPase B7L35_03370 ENOG4107RN6 Monooxygenase B7L35_03390 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) B7L35_03395 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) B7L35_03410 ENOG4108Z6B deaminase B7L35_03430 ENOG4108RTD type II secretion system protein K B7L35_03455 ENOG4105F8V Hydrolase, tatD family B7L35_03465 ENOG4107QRG dna polymerase iii B7L35_03475 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) B7L35_03480 ENOG4105BZ1 (ABC) transporter B7L35_03495 ENOG4105FA0 parb-like partition protein B7L35_03500 ENOG4107QJE Chromosome Partitioning Protein B7L35_03510 ENOG4108S0S Nucleotidyl transferase B7L35_03515 ENOG4105EHM Aminoglycoside phosphotransferase B7L35_03520 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) B7L35_03525 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) B7L35_03530 ENOG4105D2N Aldolase B7L35_03550 ENOG4108UHJ MAF-like protein B7L35_03555 ENOG4105EZE Cupin 4 family protein B7L35_03565 ENOG41080HT Transcriptional regulator, arsr family B7L35_03575 ENOG4105XPP Protein of unknown function (DUF1275) B7L35_03580 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme B7L35_03585 ENOG4105BZ1 (ABC) transporter B7L35_03595 ENOG4108ZX5 transcriptional regulator B7L35_03605 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) B7L35_03610 ENOG4105CK7 Sodium proline symporter B7L35_03615 ENOG4105EW9 transcriptional regulator AsnC family B7L35_03620 ENOG4105C26 Dehydrogenase B7L35_03625 ENOG4105YGK Pfam:UPF0157 B7L35_03640 ENOG4108T58 Mg2 transport protein CorA B7L35_03650 ENOG4108YYC ycei family B7L35_03660 ENOG4105CV1 Transketolase (EC 2.2.1.1) B7L35_03685 ENOG4108HWY Beta-lactamase B7L35_03705 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) B7L35_03710 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) B7L35_03730 ENOG4105X0I Fimbrial B7L35_03735 ENOG4105GQR Chaperone B7L35_03765 ENOG4108IPJ Membrane B7L35_03775 ENOG4105ETS cytosine purines uracil thiamine allantoin B7L35_03785 ENOG4105CC0 LysR family Transcriptional regulator B7L35_03805 ENOG41067SE Tetr family transcriptional regulator B7L35_03820 ENOG4105EW9 transcriptional regulator AsnC family B7L35_03830 ENOG4105CDA abc transporter atp-binding protein B7L35_03835 ENOG4105DRP amino acid AbC transporter B7L35_03840 ENOG4105EAD ABC transporter B7L35_03855 ENOG4107T8P acyl-Coa dehydrogenase B7L35_03870 ENOG4105D01 (LipO)protein B7L35_03875 ENOG4105D01 (LipO)protein B7L35_03880 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) B7L35_03885 ENOG4108UMI ABC transporter, permease B7L35_03890 ENOG4105C3G gtp-binding protein B7L35_03915 ENOG4108UMN azlc family B7L35_03920 ENOG4105ZED uncharacterized protein ygaH B7L35_03950 ENOG4105E7U AraC family transcriptional regulator B7L35_03955 ENOG4108V06 Glutathione peroxidase B7L35_03965 ENOG4105CHM Aminotransferase B7L35_03980 ENOG4105C0B DNA polymerase III (alpha subunit) B7L35_04005 ENOG4108JU3 Alkyl hydroperoxide reductase B7L35_04020 ENOG4108KB2 LysR family Transcriptional regulator B7L35_04025 ENOG4105D6J arsenicaL-resistance protein B7L35_04030 ENOG41082YX Transcriptional regulator, arsr family B7L35_04045 ENOG4105CPN adenine deaminase B7L35_04055 ENOG4105CBN LysR family transcriptional regulator B7L35_04065 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease B7L35_04075 ENOG4105E2B Taurine dioxygenase B7L35_04080 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component B7L35_04085 ENOG4108IY8 ABC, transporter B7L35_04090 ENOG4106FTQ Taurine ABC transporter, periplasmic B7L35_04100 ENOG4105C54 Major Facilitator superfamily B7L35_04125 ENOG4105C4M (Ubiquinol oxidase) subunit I B7L35_04130 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii B7L35_04135 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7L35_04140 ENOG4108K70 Transcriptional regulator B7L35_04160 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) B7L35_04165 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase B7L35_04175 ENOG4105DXI Major Facilitator superfamily B7L35_04190 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7L35_04195 ENOG41067MG lrgb family B7L35_04200 ENOG4105VAW lrga family B7L35_04205 ENOG4105CMU LysR family (Transcriptional regulator B7L35_04210 ENOG4108SHQ Glutathione S-transferase B7L35_04215 ENOG4105CYM Glutathione S-transferase B7L35_04220 ENOG4105CBN LysR family transcriptional regulator B7L35_04225 ENOG4105CHR reductase B7L35_04235 ENOG4105D7W serine acetyltransferase B7L35_04240 ENOG4105ESN nucleotide-binding protein B7L35_04245 ENOG4105C9B Cysteine desulfurase B7L35_04255 ENOG4105EXG Transcriptional regulator B7L35_04260 ENOG4105CT1 (ABC) transporter B7L35_04265 ENOG4107RP9 extracellular solute-binding protein, family 3 B7L35_04270 ENOG4105CDA abc transporter atp-binding protein B7L35_04275 ENOG4108HW4 amino acid AbC transporter B7L35_04280 ENOG4105EAD ABC transporter B7L35_04290 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase B7L35_04295 ENOG4105BZU Histidine kinase B7L35_04305 ENOG4105EW9 transcriptional regulator AsnC family B7L35_04315 ENOG4105KT5 UmuD protein B7L35_04335 ENOG4105CYX Short-chain dehydrogenase reductase Sdr B7L35_04380 ENOG4105HEI LysR family (Transcriptional regulator B7L35_04400 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_04405 ENOG4105R8C Transcriptional regulator B7L35_04410 ENOG4105C1G acyl-Coa dehydrogenase B7L35_04415 ENOG4107QX3 carboxylase B7L35_04420 ENOG4105E39 Enoyl-CoA hydratase B7L35_04435 ENOG4105CC0 LysR family Transcriptional regulator B7L35_04450 ENOG4105CSU acyl-Coa dehydrogenase B7L35_04460 ENOG4105EQ0 Major Facilitator superfamily B7L35_04470 ENOG4107QNJ CoA-transferase subunit B B7L35_04475 ENOG4107QP7 CoA-transferase subunit A B7L35_04480 ENOG4107RGD Major Facilitator superfamily B7L35_04485 ENOG4105C1G acyl-Coa dehydrogenase B7L35_04490 ENOG4105E39 Enoyl-CoA hydratase B7L35_04495 ENOG4108R85 Short chain dehydrogenase B7L35_04500 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7L35_04505 ENOG4105CHU acetyl-coa acetyltransferase B7L35_04515 ENOG4105EQ0 Major Facilitator superfamily B7L35_04520 ENOG4105EA8 2-Nitropropane dioxygenase B7L35_04525 ENOG4108UKI Enoyl-CoA hydratase B7L35_04540 ENOG4105C1G acyl-Coa dehydrogenase B7L35_04545 ENOG4107RGD Major Facilitator superfamily B7L35_04550 ENOG4108KAZ Involved in phosphonate degradation (By similarity) B7L35_04555 ENOG4107STF Involved in phosphonate degradation (By similarity) B7L35_04565 ENOG4107RCV ABC transporter, permease B7L35_04570 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) B7L35_04575 ENOG4105C4Y ABC transporter B7L35_04590 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase B7L35_04595 ENOG4107HP6 Transcriptional regulator B7L35_04605 ENOG4105HEI LysR family (Transcriptional regulator B7L35_04610 ENOG4105CPW cytochrome b561 B7L35_04615 ENOG4107VGR Catalase B7L35_04655 ENOG4108TGR phosphatase B7L35_04670 ENOG4107YAU phenylacetic acid degradation protein B7L35_04680 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein B7L35_04685 ENOG4105DZS Phenylacetate-CoA ligase B7L35_04690 ENOG4105CHU acetyl-coa acetyltransferase B7L35_04695 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7L35_04700 ENOG4108UKI Enoyl-CoA hydratase B7L35_04705 ENOG4105E39 Enoyl-CoA hydratase B7L35_04710 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) B7L35_04715 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit B7L35_04720 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit B7L35_04725 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit B7L35_04730 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit B7L35_04735 ENOG4105DXM phenylacetic acid degradation protein B7L35_04740 ENOG4105EJQ L-serine dehydratase B7L35_04745 ENOG4107QTZ amino acid B7L35_04750 ENOG4105CZJ Aldehyde dehydrogenase B7L35_04775 ENOG4105MWK D-amino acid dehydrogenase, small subunit B7L35_04795 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7L35_04810 ENOG4108Z4X TRANSCRIPTIONal B7L35_04820 ENOG4105WPN DNA integration recombination invertion protein B7L35_04835 ENOG4105EMY transcriptional regulator B7L35_04865 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit B7L35_04875 ENOG4105UYK outer membrane protein a B7L35_04955 ENOG4108HW3 (ABC) transporter B7L35_04965 ENOG4105MRR Transcriptional regulator (By similarity) B7L35_04985 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF B7L35_04990 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase B7L35_05005 ENOG4105E2A Dehydrogenase B7L35_05015 ENOG4105R8C Transcriptional regulator B7L35_05020 ENOG4105D5G Transposase B7L35_05035 ENOG4107R4J Chloride channel B7L35_05040 ENOG4108JIK carboxylase B7L35_05060 ENOG4105C5A transporter B7L35_05065 ENOG4108WAV Transcriptional regulator B7L35_05095 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) B7L35_05115 ENOG4105D2S major facilitator superfamily B7L35_05130 ENOG4105D1S lipid A biosynthesis B7L35_05135 ENOG4105BZU Histidine kinase B7L35_05140 ENOG4107AQZ Membrane B7L35_05160 ENOG4108Z4U Ferredoxin B7L35_05205 ENOG4108IUZ ABC transporter B7L35_05210 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA B7L35_05220 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase B7L35_05225 ENOG4105C2X Arabinose 5-phosphate isomerase B7L35_05265 ENOG4107YPT transcriptional regulator B7L35_05295 ENOG4105II7 pyrroline-5-carboxylate reductase B7L35_05305 ENOG4105VEQ Cold shock protein B7L35_05310 ENOG410829K Lysine exporter protein (Lyse ygga) B7L35_05340 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) B7L35_05395 ENOG4108KB2 LysR family Transcriptional regulator B7L35_05400 ENOG4105FUY alpha subunit B7L35_05405 ENOG4108UKV benzoate 1,2-dioxygenase B7L35_05410 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein B7L35_05415 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase B7L35_05420 ENOG4105DKK Benzoate B7L35_05425 ENOG4105D2S major facilitator superfamily B7L35_05440 ENOG4105CQ7 ATP-dependent helicase B7L35_05445 ENOG4105D3R alkyl hydroperoxide reductase B7L35_05455 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) B7L35_05465 ENOG4108JU3 Alkyl hydroperoxide reductase B7L35_05475 ENOG4108K3A Glutathione S-transferase B7L35_05485 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) B7L35_05505 ENOG4108TGY Glutathione S-transferase B7L35_05515 ENOG4108ZG0 Ompa motb domain protein B7L35_05520 ENOG4105CD3 dihydroorotase B7L35_05550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit B7L35_05565 ENOG4108UKZ OsmC family B7L35_05570 ENOG4107RYR Transcriptional regulator, Crp Fnr family B7L35_05575 ENOG4105CPC Aldo Keto reductase B7L35_05590 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis B7L35_05600 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase B7L35_05610 ENOG4105DFP Integrase B7L35_05640 ENOG4105E2A Dehydrogenase B7L35_05690 ENOG4105E4C Lytic transglycosylase catalytic B7L35_05850 ENOG4105CFH Aspartokinase B7L35_05860 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) B7L35_05870 ENOG4105CPW cytochrome b561 B7L35_05875 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) B7L35_05880 ENOG4105C7N Xanthine uracil vitamin C permease B7L35_05890 ENOG4105F95 Monooxygenase B7L35_05925 ENOG4105F95 Monooxygenase B7L35_05930 ENOG4105JQZ Methyltransferase B7L35_05960 ENOG4105EPF Outer membrane porin B7L35_05965 ENOG4105D2S major facilitator superfamily B7L35_05970 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) B7L35_05975 ENOG4105E6M Sulphatase-modifying factor protein B7L35_05990 ENOG4105E3J oxidoreductase B7L35_06005 ENOG4108SC4 )-transporter B7L35_06010 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase B7L35_06025 ENOG4105C1G acyl-Coa dehydrogenase B7L35_06030 ENOG4105EPF Outer membrane porin B7L35_06035 ENOG4105NI3 Protein of unknown function (DUF3237) B7L35_06050 ENOG4105JXH GntR family transcriptional regulator B7L35_06055 ENOG4105CZJ Aldehyde dehydrogenase B7L35_06065 ENOG4105EQX glucarate dehydratase B7L35_06070 ENOG4105DJB Major Facilitator Superfamily B7L35_06075 ENOG4105CTX dehydratase B7L35_06080 ENOG4105DJP Membrane B7L35_06085 ENOG4108ZX5 transcriptional regulator B7L35_06090 ENOG4107RGH Aldehyde dehydrogenase B7L35_06105 ENOG4105C85 amino acid B7L35_06125 ENOG4105C26 Dehydrogenase B7L35_06145 ENOG4105CUB amino acid B7L35_06155 ENOG4105C85 amino acid B7L35_06170 ENOG4105D5G Transposase B7L35_06225 ENOG4105D01 (LipO)protein B7L35_06230 ENOG4108M3P Membrane B7L35_06395 ENOG4105DFP Integrase B7L35_06405 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_06425 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) B7L35_06445 ENOG4108JQ5 ABC transporter B7L35_06450 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component B7L35_06455 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component B7L35_06465 ENOG4105E9H Lytic Murein transglycosylase B7L35_06470 ENOG4107RZZ dna polymerase iii epsilon subunit B7L35_06480 ENOG4105E09 nadh pyrophosphatase B7L35_06490 ENOG4105W4M Transport-associated protein B7L35_06500 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) B7L35_06510 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) B7L35_06515 ENOG4108ZUB Lysine exporter protein (Lyse ygga) B7L35_06535 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family B7L35_06540 ENOG4105D0A hydroxylase B7L35_06545 ENOG4107RAQ aminopeptidase B7L35_06580 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase B7L35_06595 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b B7L35_06605 ENOG4105D82 Glutamate dehydrogenase B7L35_06610 ENOG4108R3D Electron transport complex B7L35_06615 ENOG4105CSM endonuclease III B7L35_06635 ENOG4105CJN penicillin-binding protein B7L35_06640 ENOG4106H78 methyltransferase B7L35_06655 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) B7L35_06665 ENOG4105CQM Urea amidohydrolase subunit alpha B7L35_06695 ENOG4107RET Isocitrate lyase B7L35_06705 ENOG4105C37 (CBS) domain B7L35_06715 ENOG4105D4T Citrate transporter B7L35_06730 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) B7L35_06740 ENOG4108MRJ B7L35_06760 ENOG4105VCQ rubredoxin B7L35_06765 ENOG4107QZF nitrite reductase NADPH large subunit B7L35_06775 ENOG4105C5Q Transcriptional regulator B7L35_06795 ENOG4107U91 Rhomboid family B7L35_06800 ENOG4105CV6 ABC transporter, permease B7L35_06805 ENOG4108I0Y (ABC) transporter B7L35_06810 ENOG4108UJV acyl-CoA thioesterase i B7L35_06830 ENOG4107RNH Outer membrane receptor FepA B7L35_06845 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) B7L35_06850 ENOG4105E6M Sulphatase-modifying factor protein B7L35_06865 ENOG4105CJ3 phosphate transporter B7L35_06870 ENOG4105C3R Methionine synthase B7L35_06890 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) B7L35_06895 ENOG4105EU0 Major facilitator Superfamily B7L35_06900 ENOG4108R6W Transcriptional regulator, ARAC family B7L35_06905 ENOG4105CSV Glutaminase B7L35_06910 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) B7L35_06915 ENOG4105CSH Transporter B7L35_06925 ENOG4105C7K acetolactate synthase B7L35_06940 ENOG4105CHR reductase B7L35_06945 ENOG4108MXF Alpha Beta Hydrolase B7L35_06955 ENOG4105DJB Major Facilitator Superfamily B7L35_06970 ENOG4105CHR reductase B7L35_06990 ENOG41069M3 Transcriptional regulator B7L35_07005 ENOG4106YT9 Enoyl-CoA hydratase B7L35_07015 ENOG4105CND Glycosyl transferase, family 2 B7L35_07020 ENOG4107BJW polysaccharide deacetylase B7L35_07030 ENOG4108VWS Yaeq family B7L35_07040 ENOG4105CKI cobalamin synthesis protein B7L35_07060 ENOG4105C94 Transporter B7L35_07065 ENOG4105C94 Transporter B7L35_07070 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) B7L35_07095 ENOG4107QK5 Homocysteine s-methyltransferase B7L35_07100 ENOG4105D5Q Arginine ornithine antiporter B7L35_07125 ENOG4108YNN Heme oxygenase B7L35_07155 ENOG4108SF5 RNA Polymerase B7L35_07165 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7L35_07170 ENOG4105C54 Major Facilitator superfamily B7L35_07185 ENOG4105CAQ asparagine synthetase B7L35_07200 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) B7L35_07205 ENOG4108SUT Major Facilitator Superfamily B7L35_07210 ENOG4105KVH Transcriptional regulator B7L35_07275 ENOG4105DFP Integrase B7L35_07370 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) B7L35_07410 ENOG4105K4U addiction module toxin, RelE StbE family B7L35_07465 ENOG4105D5G Transposase B7L35_07730 ENOG41083X2 DNA polymerase III, epsilon subunit B7L35_07760 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) B7L35_07765 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7L35_07770 ENOG4105CW7 secretion protein, HlyD family B7L35_07775 ENOG4108VUY thioesterase Superfamily protein B7L35_07780 ENOG4105D52 delta-aminolevulinic acid dehydratase B7L35_07785 ENOG4105MWK D-amino acid dehydrogenase, small subunit B7L35_07790 ENOG4105ECP epimerase B7L35_07810 ENOG4107RH8 nuclease SbcCD subunit D B7L35_07815 ENOG4105EYH Exonuclease B7L35_07820 ENOG4105DFA alanine racemase domain protein B7L35_07825 ENOG4105CZX twitching motility protein B7L35_07830 ENOG4105CZX twitching motility protein B7L35_07835 ENOG41090R7 Ferric uptake B7L35_07865 ENOG4105E7A Glutamine amidotransferase B7L35_07880 ENOG4107QKV phosphomannomutase B7L35_07890 ENOG4105C4R Atp-dependent dna helicase B7L35_07895 ENOG4108ZG0 Ompa motb domain protein B7L35_07900 ENOG4106HNH Acyl-transferase B7L35_07915 ENOG4107QMS site-determining protein B7L35_07935 ENOG4105CNU cell division protein FtsK B7L35_07940 ENOG4105C3M thioredoxin reductase B7L35_07945 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) B7L35_07955 ENOG4105KEG ribosomal-protein-alanine acetyltransferase B7L35_08000 ENOG4108YXA Membrane B7L35_08005 ENOG4105EUB pirin domain protein B7L35_08015 ENOG4105C4K Nad synthetase B7L35_08030 ENOG4105E3J oxidoreductase B7L35_08035 ENOG4105C26 Dehydrogenase B7L35_08040 ENOG4105DVW rieske (2Fe-2S) B7L35_08050 ENOG4105C94 Transporter B7L35_08055 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) B7L35_08060 ENOG4105EJC lysr family transcriptional regulator B7L35_08080 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding B7L35_08100 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase B7L35_08105 ENOG4105C34 Pseudouridine synthase B7L35_08110 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane B7L35_08115 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) B7L35_08130 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) B7L35_08160 ENOG4105C5T Phosphoribosyl pyrophosphate synthase B7L35_08190 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) B7L35_08200 ENOG4105DWF phosphomethylpyrimidine kinase B7L35_08205 ENOG4109066 lysm domain bon superfamily protein B7L35_08215 ENOG4105CHR reductase B7L35_08220 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase B7L35_08230 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein B7L35_08235 ENOG4108BPE -transporting atpase B7L35_08240 ENOG4107RTD sua5 ycio yrdc ywlc family protein B7L35_08245 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) B7L35_08250 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) B7L35_08255 ENOG4105FE9 pseudouridine synthase B7L35_08265 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) B7L35_08270 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) B7L35_08280 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) B7L35_08285 ENOG4108K4C ec 3.1.3.12 B7L35_08290 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase B7L35_08295 ENOG4106UW1 Major Facilitator superfamily B7L35_08315 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) B7L35_08325 ENOG4105HF0 Membrane B7L35_08340 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY B7L35_08350 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) B7L35_08405 ENOG4105D1F ATP-binding protein B7L35_08415 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) B7L35_08445 ENOG4105K6H D-cysteine desulfhydrase B7L35_08450 ENOG4105CBX hi0933 family B7L35_08470 ENOG4105DP0 ferredoxin-NADP reductase B7L35_08475 ENOG4105DUM transcriptional regulator, lysR family B7L35_08495 ENOG4105C8S subunit m B7L35_08500 ENOG4105D65 subunit l B7L35_08510 ENOG4107UFS subunit j B7L35_08525 ENOG4108IEH NADH dehydrogenase subunit g B7L35_08530 ENOG4107QIZ NADH dehydrogenase B7L35_08535 ENOG4105GKE subunit e B7L35_08555 ENOG4105BZU Histidine kinase B7L35_08565 ENOG4105E0F Histidine kinase B7L35_08570 ENOG4107EXC regulatoR B7L35_08580 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) B7L35_08590 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) B7L35_08600 ENOG4105JAB phenazine biosynthesis protein, phzf family B7L35_08640 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) B7L35_08645 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) B7L35_08655 ENOG4105DZ2 Transcriptional regulator B7L35_08685 ENOG4106P55 Transcriptional regulator B7L35_08705 ENOG4106P55 Transcriptional regulator B7L35_08710 ENOG4107EFR Flavocytochrome c B7L35_08720 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F B7L35_08725 ENOG4107RGD Major Facilitator superfamily B7L35_08730 ENOG4105C1G acyl-Coa dehydrogenase B7L35_08735 ENOG4105ETT transcriptional Regulator, LysR family B7L35_08775 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) B7L35_08780 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) B7L35_08785 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) B7L35_08800 ENOG4105VR0 copper resistance B7L35_08805 ENOG4105E3B Multicopper oxidase B7L35_08815 ENOG4108HCJ Hydrolase B7L35_08820 ENOG4105DJV ribulose-phosphate 3-epimerase B7L35_08830 ENOG4105C4W S-formylglutathione hydrolase B7L35_08845 ENOG41072GX Peptidase M22 Glycoprotease B7L35_08850 ENOG4108Z0R Transferase B7L35_08870 ENOG4105CRQ synthase (Component I) B7L35_08880 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) B7L35_08885 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) B7L35_08890 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) B7L35_08960 ENOG4105K56 Transcriptional regulator B7L35_08965 ENOG4108ZHJ Organic hydroperoxide resistance protein B7L35_08970 ENOG4107QHF type ii secretion system protein e B7L35_08990 ENOG4105C2M dna polymerase I B7L35_08995 ENOG4108VIA integral membrane protein B7L35_09000 ENOG4105II7 pyrroline-5-carboxylate reductase B7L35_09005 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) B7L35_09015 ENOG4105C9X ppx gppa phosphatase B7L35_09025 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) B7L35_09040 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) B7L35_09065 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) B7L35_09085 ENOG4105W39 Membrane B7L35_09090 ENOG4105CYM Glutathione S-transferase B7L35_09110 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_09115 ENOG4105N42 UPF0307 protein B7L35_09120 ENOG41080Z8 PHOSPHOCARRIER protein B7L35_09140 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase B7L35_09145 ENOG4105DJ0 Poly(A) Polymerase B7L35_09150 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein B7L35_09155 ENOG4105DXN mazG family B7L35_09165 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) B7L35_09180 ENOG4105C6T cysteine synthase B7L35_09185 ENOG4105BZU Histidine kinase B7L35_09190 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase B7L35_09195 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7L35_09200 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) B7L35_09215 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) B7L35_09220 ENOG4105W8H transhydrogenase (subunit alpha B7L35_09225 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) B7L35_09230 ENOG4106UX7 integral membrane protein B7L35_09250 ENOG4105H3G oxidoreductase B7L35_09255 ENOG4105C3M thioredoxin reductase B7L35_09260 ENOG4105CAU Arsenical resistance protein, ArsH B7L35_09265 ENOG4105D6J arsenicaL-resistance protein B7L35_09275 ENOG4105KBH arsR family transcriptional regulator B7L35_09300 ENOG4105CE1 Ferrous iron transport protein b B7L35_09345 ENOG4105E3B Multicopper oxidase B7L35_09360 ENOG4105GR3 Histidine kinase B7L35_09400 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) B7L35_09410 ENOG4107RSM transcriptional regulator B7L35_09415 ENOG4105CUZ uba thif-type nad fad binding protein B7L35_09420 ENOG4107QM5 aconitate hydratase B7L35_09425 ENOG4105F8V Hydrolase, tatD family B7L35_09440 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) B7L35_09455 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium B7L35_09465 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein B7L35_09470 ENOG4108WUH Transcriptional regulator, TetR family B7L35_09480 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_09490 ENOG4108I6A alcohol dehydrogenase B7L35_09500 ENOG4105C4W S-formylglutathione hydrolase B7L35_09515 ENOG4108JA1 polyketide synthase B7L35_09520 ENOG4107QPD alcohol dehydrogenase B7L35_09525 ENOG410810E transcriptional regulator, lysR family B7L35_09530 ENOG4105EMU Dehydrogenase B7L35_09580 ENOG4105BZU Histidine kinase B7L35_09590 ENOG4108ZP8 Acetolactate synthase small subunit B7L35_09595 ENOG4105C7K acetolactate synthase B7L35_09625 ENOG4105DJY efflux transporter, rnd family, mfp subunit B7L35_09630 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) B7L35_09635 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7L35_09640 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH B7L35_09650 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) B7L35_09655 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) B7L35_09665 ENOG4105VW4 glutaredoxin 3 B7L35_09685 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) B7L35_09705 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) B7L35_09725 ENOG4105WVQ Fe-S assembly protein IscX B7L35_09740 ENOG4105CN1 protease B7L35_09755 ENOG4106HB6 Alpha beta hydrolase B7L35_09765 ENOG4105C26 Dehydrogenase B7L35_09770 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family B7L35_09775 ENOG4105C6Z Gluconate B7L35_09780 ENOG4108UHU Aldolase B7L35_09785 ENOG4105C01 Dihydroxy-acid dehydratase B7L35_09790 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) B7L35_09795 ENOG4108DNC Involved in acetate metabolism (By similarity) B7L35_09800 ENOG4107GFK fumarate B7L35_09820 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) B7L35_09830 ENOG4108ESX Receptor B7L35_09840 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) B7L35_09850 ENOG4105DWV Homoserine O-trans-acetylase B7L35_09955 ENOG4105CIY formyltetrahydrofolate deformylase B7L35_09965 ENOG4107RGH Aldehyde dehydrogenase B7L35_09970 ENOG4105KDC 50s ribosomal protein l28 B7L35_09975 ENOG4105W0E 50S ribosomal protein L33 B7L35_09980 ENOG4105CKD glutathione-regulated potassium-efflux system protein B7L35_10000 ENOG4105VFU Rna-binding protein B7L35_10005 ENOG4105C4R Atp-dependent dna helicase B7L35_10020 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) B7L35_10030 ENOG4105KVH Transcriptional regulator B7L35_10040 ENOG41069P5 Protein slyX homolog B7L35_10045 ENOG4105C5H ABC transporter B7L35_10050 ENOG4105N14 lysine exporter protein LysE YggA B7L35_10055 ENOG4105D1S lipid A biosynthesis B7L35_10065 ENOG4105CK2 sodium dicarboxylate symporter B7L35_10120 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) B7L35_10145 ENOG4105DUM transcriptional regulator, lysR family B7L35_10170 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase B7L35_10185 ENOG4108W5M transcriptional regulator B7L35_10200 ENOG4105D29 Helix-turn-helix type 11 domain protein B7L35_10205 ENOG4107XGZ Hydrolase B7L35_10210 ENOG4105EI2 Pseudouridine synthase B7L35_10220 ENOG4105C03 ribonuclease B7L35_10240 ENOG4105CBN LysR family transcriptional regulator B7L35_10245 ENOG4105EMU Dehydrogenase B7L35_10250 ENOG4105CSA Coproporphyrinogen iii oxidase B7L35_10260 ENOG4107QI1 Mate efflux family protein B7L35_10270 ENOG4107T8P acyl-Coa dehydrogenase B7L35_10300 ENOG4105BZ8 glutamate synthase B7L35_10310 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) B7L35_10315 ENOG4105C5X domain protein B7L35_10330 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) B7L35_10340 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase B7L35_10350 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) B7L35_10355 ENOG4108JU5 Magnesium and cobalt efflux protein B7L35_10360 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) B7L35_10365 ENOG4108Z7R Chaperone CsaA B7L35_10375 ENOG4108VAU general secretion pathway protein G B7L35_10380 ENOG4105D7Q type ii secretion system B7L35_10385 ENOG4105C25 Primosomal protein n' B7L35_10390 ENOG4105CKD glutathione-regulated potassium-efflux system protein B7L35_10405 ENOG4105DVC DnaJ domain protein B7L35_10410 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) B7L35_10415 ENOG4107QUT magnesium and cobalt transport protein CorA B7L35_10435 ENOG4107QYX exodeoxyribonuclease v alpha B7L35_10440 ENOG4107QKA exodeoxyribonuclease V beta B7L35_10445 ENOG4105DSY exodeoxyribonuclease V, gamma B7L35_10455 ENOG4105CSR polyphosphate kinase 2 B7L35_10465 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) B7L35_10480 ENOG41061H0 Monooxygenase B7L35_10485 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase B7L35_10500 ENOG4105D65 subunit l B7L35_10505 ENOG4108ZE9 Monovalent cation H antiporter subunit C B7L35_10510 ENOG4107R4Z monovalent cation h antiporter subunit d B7L35_10515 ENOG4105SC1 monovalent cation H antiporter subunit E B7L35_10520 ENOG4105W4C monovalent cation H antiporter subunit F B7L35_10525 ENOG4105KJM monovalent cation h antiporter subunit g B7L35_10540 ENOG4105CHV Transcription elongation factor NusA B7L35_10565 ENOG4107EJC Preprotein translocase subunit SecG B7L35_10575 ENOG4107QHF type ii secretion system protein e B7L35_10590 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) B7L35_10600 ENOG4105C2N RNA methyltransferase TrmH family group 3 B7L35_10615 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) B7L35_10625 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) B7L35_10655 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) B7L35_10660 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase B7L35_10720 ENOG4107ZXU DSBA oxidoreductase B7L35_10735 ENOG4105D5G Transposase B7L35_10745 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) B7L35_10760 ENOG4105D3Y Na H antiporter B7L35_10765 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) B7L35_10815 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) B7L35_10820 ENOG4105PM1 preprotein translocase subunit SecE B7L35_10860 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) B7L35_10865 ENOG4105TV9 FHA Domain-Containing protein B7L35_10870 ENOG4105GVR general secretion pathway protein D B7L35_10885 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS B7L35_10910 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) B7L35_10915 ENOG4108NEV two component transcriptional regulator, LytTR family B7L35_10920 ENOG4108HRK Histidine kinase B7L35_10935 ENOG4108UTW Plays a role in the regulation of phosphate uptake B7L35_10940 ENOG4105DFG type I secretion outer membrane protein B7L35_10945 ENOG4108RNG Permease of the drug metabolite transporter B7L35_10970 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) B7L35_10975 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters B7L35_10980 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) B7L35_10985 ENOG4105CNI cell division protein FtsW B7L35_11000 ENOG4105CE1 Ferrous iron transport protein b B7L35_11010 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) B7L35_11015 ENOG4105T95 Thiol disulfide interChange protein B7L35_11020 ENOG4105D6E homoserine dehydrogenase B7L35_11030 ENOG41061WM D-Alanyl-D-Alanine B7L35_11040 ENOG4107TUY Histidine kinase B7L35_11045 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family B7L35_11050 ENOG4105CN1 protease B7L35_11055 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) B7L35_11060 ENOG4108K5H permease YjgP YjgQ family protein B7L35_11100 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) B7L35_11110 ENOG4105BZU Histidine kinase B7L35_11140 ENOG4108HWY Beta-lactamase B7L35_11150 ENOG4105F6A helicase B7L35_11165 ENOG4105CHH sulfate transporter B7L35_11210 ENOG4105C0P Mg chelatase subunit ChlI B7L35_11215 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7L35_11220 ENOG4105FB2 class II Aldolase B7L35_11225 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7L35_11235 ENOG41090KI Outer membrane porin B7L35_11240 ENOG4105F0N pyrophosphate phospho-hydrolase B7L35_11255 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_11260 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7L35_11265 ENOG41079KZ Major Facilitator Superfamily B7L35_11270 ENOG4105EN6 Membrane B7L35_11275 ENOG4105K5B UPF0225 protein B7L35_11280 ENOG4105EE5 Membrane protein terC B7L35_11285 ENOG4108URH decarboxylase B7L35_11290 ENOG4105C0R drug resistance transporter emrb qaca subfamily B7L35_11300 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) B7L35_11315 ENOG4105CCT upf0313 protein B7L35_11335 ENOG4105CS1 NAD(P)H quinone oxidoreductase B7L35_11345 ENOG4105C6T cysteine synthase B7L35_11380 ENOG4105Y7M Transcriptional regulator, TetR family B7L35_11415 ENOG4105C79 DNA protecting protein DprA B7L35_11430 ENOG4108IND Tetr family transcriptional regulator B7L35_11435 ENOG4107RTG Major Facilitator superfamily B7L35_11445 ENOG4108V06 Glutathione peroxidase B7L35_11455 ENOG41090VV Protein of unknown function (DUF2846) B7L35_11490 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) B7L35_11515 ENOG4105FDK ABC transporter B7L35_11520 ENOG4105FAV ABC, transporter B7L35_11530 ENOG4105EZR dyp-type peroxidase family protein B7L35_11540 ENOG4107R1I NAD-dependent malic enzyme B7L35_11565 ENOG4105EUB pirin domain protein B7L35_11585 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) B7L35_11590 ENOG4106MP8 UPF0754 membrane protein B7L35_11595 ENOG4108VBZ doxx family B7L35_11600 ENOG4105DQR SNARE associated Golgi B7L35_11615 ENOG4107QJE Chromosome Partitioning Protein B7L35_11625 ENOG4107PSF BolA-like protein B7L35_11640 ENOG4105CSH Transporter B7L35_11645 ENOG4105E39 Enoyl-CoA hydratase B7L35_11650 ENOG4105E39 Enoyl-CoA hydratase B7L35_11655 ENOG4105C1G acyl-Coa dehydrogenase B7L35_11665 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase B7L35_11670 ENOG4105C26 Dehydrogenase B7L35_11680 ENOG4105C85 amino acid B7L35_11685 ENOG4105C85 amino acid B7L35_11690 ENOG4105M4H endoribonuclease L-psp B7L35_11705 ENOG4105EW9 transcriptional regulator AsnC family B7L35_11730 ENOG4105D3G Pseudouridine synthase B7L35_11805 ENOG4108I0Z Aconitate hydratase B7L35_11810 ENOG4105BZN citrate synthase B7L35_11815 ENOG4105CR4 methylisocitrate lyase B7L35_11820 ENOG4105DRR Transcriptional regulator, GntR family B7L35_11825 ENOG4105CGF Aromatic amino acid aminotransferase B7L35_11830 ENOG4105CXG d-lactate dehydrogenase B7L35_11840 ENOG41073TP transcriptional regulator B7L35_11845 ENOG4105DAA L-lactate B7L35_11850 ENOG4107QKV phosphomannomutase B7L35_11855 ENOG4105CMR udp-glucose 4-epimerase B7L35_11865 ENOG4105C6Y Udp-glucose 6-dehydrogenase B7L35_11870 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase B7L35_11875 ENOG4105D3Q Sugar transferase B7L35_11880 ENOG4107UKG Glycosyl transferase, family 4 B7L35_11895 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase B7L35_11930 ENOG4105F0R Cytidylyltransferase B7L35_11935 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) B7L35_11945 ENOG4105D7W serine acetyltransferase B7L35_11950 ENOG4105D2T synthase B7L35_11955 ENOG4107SE4 UDP-N-acetylglucosamine 2-epimerase B7L35_11960 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase B7L35_11970 ENOG4107QQG Dehydrogenase B7L35_11975 ENOG4105DAY polysaccharide export protein B7L35_11985 ENOG4105D75 Capsular exopolysaccharide family B7L35_11990 ENOG4108V1T peptidylprolyl cis-trans isomerase B7L35_11995 ENOG4108V1T peptidylprolyl cis-trans isomerase B7L35_12000 ENOG4105CJR Integral membrane protein (MviN B7L35_12005 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase B7L35_12010 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase B7L35_12040 ENOG41062JF Transcriptional regulator B7L35_12055 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) B7L35_12060 ENOG4105UBK short-chain dehydrogenase reductase B7L35_12075 ENOG4107QZM n-acetylglutamate synthase B7L35_12080 ENOG4105GVF (ABC) transporter B7L35_12085 ENOG4105GVF (ABC) transporter B7L35_12090 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) B7L35_12095 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component B7L35_12100 ENOG4108VM9 ABC, transporter B7L35_12105 ENOG4108R86 Transcriptional regulator B7L35_12110 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) B7L35_12120 ENOG4105DTN riboflavin biosynthesis protein ribF B7L35_12125 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) B7L35_12135 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase B7L35_12175 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) B7L35_12180 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) B7L35_12185 ENOG4105D74 hydrolase B7L35_12195 ENOG4108821 RND type efflux pump B7L35_12200 ENOG4108821 RND type efflux pump B7L35_12205 ENOG4108821 RND type efflux pump B7L35_12210 ENOG4105C5H ABC transporter B7L35_12215 ENOG4105DQR SNARE associated Golgi B7L35_12225 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7L35_12235 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) B7L35_12245 ENOG4105VG0 50S ribosomal protein l34 B7L35_12260 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins B7L35_12275 ENOG4105PGM cation diffusion facilitator family transporter B7L35_12280 ENOG4105T95 Thiol disulfide interChange protein B7L35_12290 ENOG4108UGV hypoxanthine phosphoribosyltransferase B7L35_12295 ENOG4107QUY Guanine deaminase B7L35_12305 ENOG4106032 Glutathionylspermidine synthase B7L35_12315 ENOG4105DU1 integral membrane protein, terc B7L35_12320 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase B7L35_12330 ENOG4105DFU Cell wall formation (By similarity) B7L35_12345 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) B7L35_12350 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit B7L35_12355 ENOG4105CVE Lytic murein transglycosylase B7L35_12410 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) B7L35_12450 ENOG4105C8J )-transporter B7L35_12460 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B B7L35_12485 ENOG4108W5M transcriptional regulator B7L35_12490 ENOG4105C2W permease B7L35_12500 ENOG4108IG5 Transcriptional regulator B7L35_12505 ENOG4105DJY efflux transporter, rnd family, mfp subunit B7L35_12540 ENOG4105F27 Major Facilitator B7L35_12545 ENOG4105CV8 reductase B7L35_12550 ENOG4105HEI LysR family (Transcriptional regulator B7L35_12570 ENOG4105DQ4 alcohol dehydrogenase B7L35_12575 ENOG4108R3E Dna-3-methyladenine glycosylase i B7L35_12590 ENOG4105CEN a g-specific adenine glycosylase B7L35_12610 ENOG4108ZZ3 UPF0260 protein B7L35_12620 ENOG4105D1H recombination factor protein RarA B7L35_12625 ENOG4105S64 Formate nitrite transporter B7L35_12645 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) B7L35_12650 ENOG4108RWI nicotinamidase B7L35_12655 ENOG4105C09 Bile acid B7L35_12660 ENOG4107QI1 Mate efflux family protein B7L35_12665 ENOG4105EWC Purine nucleoside phosphorylase B7L35_12685 ENOG4108RXX maleylacetoacetate isomerase B7L35_12695 ENOG4105C85 amino acid B7L35_12705 ENOG4105CKI cobalamin synthesis protein B7L35_12715 ENOG4105CZE histidine utilization repressor B7L35_12720 ENOG41090B9 response to stress B7L35_12735 ENOG4105C85 amino acid B7L35_12745 ENOG41088SP formiminoglutamate hydrolase B7L35_12760 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) B7L35_12765 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) B7L35_12775 ENOG4108ZAI phosphatidylglycerophosphatase a B7L35_12780 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) B7L35_12795 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) B7L35_12835 ENOG4105KHC sulfurtransferase B7L35_12850 ENOG4105BZU Histidine kinase B7L35_12855 ENOG4105CK6 Two component transcriptional regulator (Winged helix family B7L35_12870 ENOG4107QJQ Mate efflux family protein B7L35_12875 ENOG4105CHM Aminotransferase B7L35_12880 ENOG4106BRA Membrane B7L35_12895 ENOG4105D9M gamma-glutamylcysteine synthetase B7L35_12905 ENOG4105CS6 Rhs element vgr protein B7L35_12970 ENOG4105IPS esterase B7L35_12975 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7L35_13025 ENOG4105EWI Short-chain dehydrogenase reductase Sdr B7L35_13030 ENOG4108Z2U ureidoglycolate hydrolase B7L35_13040 ENOG41061H0 Monooxygenase B7L35_13055 ENOG41084YZ Hydrolase B7L35_13085 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) B7L35_13090 ENOG4105BZU Histidine kinase B7L35_13105 ENOG4105KUZ arsenate reductase B7L35_13110 ENOG4105CGK Exodeoxyribonuclease III B7L35_13135 ENOG4105D7Z glutathione synthase B7L35_13155 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) B7L35_13160 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) B7L35_13165 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) B7L35_13180 ENOG41063SB peptidase B7L35_13185 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) B7L35_13190 ENOG4107QSN dihydrolipoamide acetyltransferase B7L35_13205 ENOG4105E0K tonB-dependent siderophore receptor B7L35_13220 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) B7L35_13235 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) B7L35_13255 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_13260 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase B7L35_13270 ENOG4105D64 Mechanosensitive ion channel B7L35_13280 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) B7L35_13285 ENOG4108W2Y isochorismatase B7L35_13295 ENOG4105FBW Monooxygenase B7L35_13300 ENOG4108UZX fmn reductase B7L35_13315 ENOG4105BZU Histidine kinase B7L35_13320 ENOG41062QD Membrane B7L35_13325 ENOG4107QN1 sodium solute B7L35_13335 ENOG4105C94 Transporter B7L35_13345 ENOG4105BZU Histidine kinase B7L35_13350 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) B7L35_13355 ENOG4108WUH Transcriptional regulator, TetR family B7L35_13360 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein B7L35_13370 ENOG4105RA2 Membrane B7L35_13375 ENOG4105DWF phosphomethylpyrimidine kinase B7L35_13385 ENOG4107RDB Major Facilitator B7L35_13390 ENOG4108UUM single-stranded DNA-binding protein B7L35_13400 ENOG4108UMN azlc family B7L35_13410 ENOG4105C85 amino acid B7L35_13420 ENOG4108JPW Aminotransferase B7L35_13425 ENOG4105C26 Dehydrogenase B7L35_13435 ENOG4105CHJ isochorismatase hydrolase B7L35_13440 ENOG4105EUB pirin domain protein B7L35_13465 ENOG4105D94 Major Facilitator Superfamily B7L35_13470 ENOG4106NZI LysR family Transcriptional regulator B7L35_13520 ENOG4105CPC Aldo Keto reductase B7L35_13545 ENOG4105C2J ABC transporter B7L35_13555 ENOG4108UQN AraC family transcriptional regulator B7L35_13610 ENOG4105CUV Homoserine Kinase B7L35_13625 ENOG41061CK Antibiotic biosynthesis monooxygenase B7L35_13640 ENOG4105BZ1 (ABC) transporter B7L35_13660 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) B7L35_13690 ENOG4105CYC Transferase B7L35_13695 ENOG4105E0F Histidine kinase B7L35_13700 ENOG4105DPZ Two component transcriptional regulator (Winged helix family B7L35_13710 ENOG4105CHH sulfate transporter B7L35_13715 ENOG4105PDP Short chain dehydrogenase B7L35_13725 ENOG4105C5H ABC transporter B7L35_13790 ENOG4108IQI permease B7L35_13815 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein B7L35_13830 ENOG4105CJN penicillin-binding protein B7L35_13835 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) B7L35_13840 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) B7L35_13855 ENOG4105DHI Methyltransferase B7L35_13860 ENOG4108JQC penicillin-binding protein 1A B7L35_13885 ENOG4105E4G Type IV pilus B7L35_13905 ENOG4105CBC glutamate synthase B7L35_13910 ENOG4105BZ8 glutamate synthase B7L35_13920 ENOG4108V0P LemA family B7L35_13925 ENOG4105HA9 of methanol dehydrogenase type B7L35_13945 ENOG4108YSG O-Antigen polymerase B7L35_13950 ENOG4108UQY Iron-storage protein B7L35_13960 ENOG4105KME endoribonuclease L-psp B7L35_13965 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) B7L35_13975 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) B7L35_14025 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) B7L35_14040 ENOG4107IFA Lipase (EC 3.1.1.3) B7L35_14045 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) B7L35_14050 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) B7L35_14075 ENOG4108JQ1 Dehydrogenase B7L35_14080 ENOG4105CQB FAD linked oxidase domain protein B7L35_14090 ENOG4105VRH Antibiotic biosynthesis monooxygenase B7L35_14095 ENOG4105NF4 modulator of drug activity B7L35_14105 ENOG4107QF7 multi-drug B7L35_14110 ENOG4105EM2 membrane B7L35_14115 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) B7L35_14120 ENOG4105IPI Membrane B7L35_14125 ENOG4107SKI cobyrinic Acid a,c-diamide synthase B7L35_14155 ENOG4108IQI permease B7L35_14160 ENOG4105D82 Glutamate dehydrogenase B7L35_14165 ENOG4105C8Y Acetylornithine aminotransferase B7L35_14175 ENOG4105C26 Dehydrogenase B7L35_14200 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin B7L35_14235 ENOG4105D5G Transposase B7L35_14275 ENOG4105W87 Cbs domain B7L35_14280 ENOG41067S9 phage shock protein C, PspC B7L35_14290 ENOG4105CSU acyl-Coa dehydrogenase B7L35_14305 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) B7L35_14320 ENOG4105ECY inositol monophosphatase B7L35_14325 ENOG4105C1J atp-dependent rna helicase B7L35_14330 ENOG4105DHJ ABC, transporter B7L35_14335 ENOG4105CY3 ABC transporter, permease B7L35_14345 ENOG4105E3I toluene tolerance B7L35_14355 ENOG4105D7N magnesium and cobalt transport protein CorA B7L35_14360 ENOG4108URH decarboxylase B7L35_14370 ENOG4105MJ2 Competence protein B7L35_14375 ENOG4105CB5 ATP-dependent DNA helicase recG B7L35_14395 ENOG4105C29 acyl-CoA thioesterase B7L35_14400 ENOG4105CK2 sodium dicarboxylate symporter B7L35_14415 ENOG4105KPV Transcriptional regulator B7L35_14425 ENOG4105D7A ATP-binding protein B7L35_14430 ENOG4105C28 cystathionine B7L35_14435 ENOG41089BK Glutamine amido-transferase B7L35_14545 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) B7L35_14550 ENOG41067V7 50S ribosomal protein L36 B7L35_14560 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) B7L35_14585 ENOG4105C1G acyl-Coa dehydrogenase B7L35_14620 ENOG4105VKU nucleicacid-binding protein B7L35_14625 ENOG4105DGW oligopeptidase A B7L35_14630 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) B7L35_14675 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase B7L35_14680 ENOG4108K2B transcriptional regulator B7L35_14690 ENOG4107S2Z UPF0761 membrane protein B7L35_14695 ENOG4105CS1 NAD(P)H quinone oxidoreductase B7L35_14725 ENOG4105C9A Phoh family B7L35_14735 ENOG4105E4C Lytic transglycosylase catalytic B7L35_14765 ENOG4105D6S protein involved in catabolism of external DNA B7L35_14770 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase B7L35_14815 ENOG4105C1G acyl-Coa dehydrogenase B7L35_14835 ENOG4105KB2 stringent starvation protein b B7L35_14840 ENOG4107MKT Stringent starvation protein a B7L35_14845 ENOG4108UJD 30S ribosomal protein S9 B7L35_14855 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) B7L35_14860 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) B7L35_14865 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) B7L35_14885 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) B7L35_14895 ENOG4107RZC phospholipase d B7L35_14905 ENOG4105UYK outer membrane protein a B7L35_14910 ENOG4108KHX Diguanylate cyclase B7L35_14945 ENOG4107QN2 dihydrolipoyl dehydrogenase B7L35_14955 ENOG4107QPB Beta-lactamase domain protein B7L35_14960 ENOG4107U2T alpha beta B7L35_14970 ENOG4105NAU thioesterase Superfamily protein B7L35_15000 ENOG4105K9H YciI-like protein B7L35_15010 ENOG4105DB7 PHP domain protein B7L35_15015 ENOG4105FFC UPF0187 protein B7L35_15025 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase B7L35_15030 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) B7L35_15035 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) B7L35_15040 ENOG4105VIE preprotein translocase, subunit YajC B7L35_15075 ENOG4105BZU Histidine kinase B7L35_15080 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) B7L35_15085 ENOG4105CM2 brancheD-chain amino acid aminotransferase B7L35_15100 ENOG4107BJW polysaccharide deacetylase B7L35_15110 ENOG4108PQP glycosyl transferase group 1 B7L35_15125 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase B7L35_15150 ENOG4105UGU tonB-dependent Receptor B7L35_15170 ENOG4108VY7 phosphate-starvation-inducible protein PsiE B7L35_15175 ENOG4105CSU acyl-Coa dehydrogenase B7L35_15180 ENOG4105CSU acyl-Coa dehydrogenase B7L35_15190 ENOG4105EB3 Histidine kinase B7L35_15195 ENOG4105E3W Two component transcriptional regulator (Winged helix family B7L35_15200 ENOG4105CNG UPF0061 protein B7L35_15220 ENOG4108WBT adenosyltransferase B7L35_15225 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) B7L35_15235 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) B7L35_15270 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase B7L35_15290 ENOG4105D3R alkyl hydroperoxide reductase B7L35_15305 ENOG4105CSH Transporter B7L35_15310 ENOG4108UT2 hemolysin iii B7L35_15335 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase B7L35_15340 ENOG4105CHU acetyl-coa acetyltransferase B7L35_15345 ENOG4108R6W Transcriptional regulator, ARAC family B7L35_15355 ENOG4105TW1 Carbohydrate-selective porin OprB B7L35_15360 ENOG4105DZG Dehydrogenase B7L35_15365 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) B7L35_15375 ENOG410814C multidrug resistance protein B7L35_15385 ENOG4105CHU acetyl-coa acetyltransferase B7L35_15395 ENOG4108WHA ompa motb domain protein B7L35_15400 ENOG4105E0Y RtcB Protein B7L35_15405 ENOG4108IQI permease B7L35_15415 ENOG4105C2W permease B7L35_15435 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) B7L35_15445 ENOG4108VX5 3-methyladenine DNA glycosylase B7L35_15450 ENOG4105CHB tonB-dependent Receptor B7L35_15455 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase B7L35_15470 ENOG4105T95 Thiol disulfide interChange protein B7L35_15475 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) B7L35_15485 ENOG4105K78 MarR family Transcriptional regulator B7L35_15490 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA B7L35_15495 ENOG4105KWI UPF0339 protein B7L35_15520 ENOG4108UNF response regulator B7L35_15525 ENOG4105M3Z response regulator B7L35_15530 ENOG4108ZGA chew protein B7L35_15535 ENOG4105C8Q Methyl-accepting chemotaxis B7L35_15540 ENOG4105CBS Chea signal transduction histidine kinase B7L35_15555 ENOG4106HKS Entericidin EcnA/B family B7L35_15565 ENOG4105WD1 Membrane B7L35_15570 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein B7L35_15610 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) B7L35_15620 ENOG4105EM2 membrane B7L35_15625 ENOG4105C2C drug resistance transporter, Bcr CflA B7L35_15640 ENOG4105BZG amino acid carrier protein B7L35_15645 ENOG4105D78 K07001 NTE family protein B7L35_15650 ENOG4105C7B Threonine dehydratase B7L35_15660 ENOG4105C9K Endothelin-converting enzyme 1 B7L35_15685 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) B7L35_15695 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) B7L35_15700 ENOG4105DFF Rod shape-determining protein mreb B7L35_15705 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) B7L35_15710 ENOG4105VQ7 Rod shape-determining protein MreD B7L35_15715 ENOG4108Z03 MAF-like protein B7L35_15720 ENOG4105C03 ribonuclease B7L35_15725 ENOG4105D8T Acyltransferase B7L35_15735 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein B7L35_15745 ENOG4108X0B nad(p)h dehydrogenase (quinone) B7L35_15770 ENOG4105CF7 AraC family transcriptional regulator B7L35_15835 ENOG4105C85 amino acid B7L35_15840 ENOG4105C7F AcnD-accessory protein PrpF B7L35_15845 ENOG4105CTB Polyprenyl synthetase B7L35_15865 ENOG4105D78 K07001 NTE family protein B7L35_15885 ENOG4105DIJ Phosphoethanolamine transferase B7L35_15890 ENOG4105XJC Two component transcriptional regulator (Winged helix family B7L35_15895 ENOG4105DHQ Histidine kinase B7L35_15915 ENOG4108M0I Transcriptional regulator B7L35_15930 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) B7L35_15935 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) B7L35_15955 ENOG4105K8R UPF0145 protein B7L35_15960 ENOG4105K8R UPF0145 protein B7L35_15965 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7L35_15970 ENOG4105BZS acriflavin resistance protein B7L35_15975 ENOG4105C1P efflux transporter, rnd family, mfp subunit B7L35_15980 ENOG410841Q phosphoesterase PA-phosphatase related protein B7L35_16010 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) B7L35_16025 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) B7L35_16030 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) B7L35_16045 ENOG4105CUB amino acid B7L35_16060 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) B7L35_16065 ENOG41084BA UPF0250 protein B7L35_16070 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) B7L35_16100 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit B7L35_16105 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein B7L35_16115 ENOG4105E33 succinate dehydrogenase B7L35_16125 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 B7L35_16130 ENOG4105C7S Dehydrogenase B7L35_16135 ENOG4107QN2 dihydrolipoyl dehydrogenase B7L35_16145 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha B7L35_16155 ENOG4105CKW Inner membrane protein yedI B7L35_16160 ENOG4105CGZ zinc metallopeptidase B7L35_16165 ENOG4105EEQ Na H antiporter B7L35_16180 ENOG4105PNM synthesis protein B7L35_16195 ENOG41080TK Universal stress protein B7L35_16205 ENOG4108UQ8 endoribonuclease L-psp B7L35_16210 ENOG4108IG5 Transcriptional regulator B7L35_16220 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain B7L35_16225 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain B7L35_16245 ENOG4105HBR Rna-binding protein B7L35_16255 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) B7L35_16260 ENOG4105EEI dihydropteroate synthase B7L35_16310 ENOG4105CSH Transporter B7L35_16315 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) B7L35_16320 ENOG4105C6V Glycerol-3-phosphate dehydrogenase B7L35_16335 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) B7L35_16350 ENOG41080IJ Diacylglycerol kinase B7L35_16360 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase B7L35_16365 ENOG4105BZS acriflavin resistance protein B7L35_16380 ENOG4105E4C Lytic transglycosylase catalytic B7L35_16405 ENOG4108RRZ Transcription elongation factor GreB B7L35_16420 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_16455 ENOG4105BZW Glycerate kinase B7L35_16460 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit B7L35_16465 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) B7L35_16480 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) B7L35_16490 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) B7L35_16495 ENOG4105BZG amino acid carrier protein B7L35_16500 ENOG4105C85 amino acid B7L35_16510 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) B7L35_16520 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) B7L35_16525 ENOG4105N14 lysine exporter protein LysE YggA B7L35_16530 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) B7L35_16535 ENOG4105BZJ Electron transfer flavoprotein B7L35_16540 ENOG4105C10 Electron transfer flavoprotein B7L35_16545 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) B7L35_16580 ENOG4107KET secretion protein, HlyD family B7L35_16610 ENOG4105D60 lipoprotein releasing system transmembrane protein B7L35_16615 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) B7L35_16630 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) B7L35_16635 ENOG4107R6F Alpha Beta Hydrolase Fold protein B7L35_16640 ENOG4108V3E phosphoribosylglycinamide formyltransferase B7L35_16650 ENOG4105C02 permease B7L35_16705 ENOG4105KCK Peptidoglycan-associated lipoprotein B7L35_16710 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) B7L35_16720 ENOG4105M8F Biopolymer transport protein exbD tolR B7L35_16725 ENOG4105E02 MotA TolQ exbB proton channel B7L35_16730 ENOG4107YD3 Thioesterase B7L35_16735 ENOG4105CH2 amidohydrolase B7L35_16755 ENOG4108ETH Formylglycinamide ribotide synthetase B7L35_16760 ENOG4105C2C drug resistance transporter, Bcr CflA B7L35_16765 ENOG4105EGD dinuclear metal center protein, YbgI family B7L35_16770 ENOG4108UKI Enoyl-CoA hydratase B7L35_16785 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen B7L35_16800 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) B7L35_16805 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) B7L35_16820 ENOG4107R11 Transcriptional regulator B7L35_16825 ENOG4108IJ6 ABC transporter B7L35_16835 ENOG4108I5D sulfate abc transporter B7L35_16845 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein B7L35_16850 ENOG4105YAZ 4-amino-4-deoxychorismate lyase B7L35_16855 ENOG4105HHA aminodeoxychorismate lyase B7L35_16870 ENOG4108IYU L-aspartate oxidase B7L35_16875 ENOG4105C0H protease B7L35_16890 ENOG4105C3F Signal peptidase i B7L35_16905 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) B7L35_16915 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) B7L35_16920 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) B7L35_16925 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase B7L35_16930 ENOG4105EMU Dehydrogenase B7L35_16955 ENOG4105F7F Chaperone B7L35_16975 ENOG4105BZU Histidine kinase B7L35_16985 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) B7L35_16995 ENOG4105DTR rard protein B7L35_17030 ENOG4107QS8 (LipO)protein B7L35_17035 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) B7L35_17040 ENOG4105EA8 2-Nitropropane dioxygenase B7L35_17070 ENOG4107R8N Glycosyl transferase, family 2 B7L35_17085 ENOG4105CVP deoxyribo-dipyrimidine photolyase B7L35_17090 ENOG4108YZY peptidylprolyl cis-trans isomerase B7L35_17095 ENOG4105CEP NADH dehydrogenase B7L35_17100 ENOG4105DZ1 carboxypeptidase B7L35_17110 ENOG4105E9K Isocitrate dehydrogenase B7L35_17115 ENOG4108R99 pseudouridine synthase B7L35_17135 ENOG4105CBP Major Facilitator B7L35_17140 ENOG4105EGI Transcriptional regulator B7L35_17145 ENOG4108ETY sodium dicarboxylate symporter B7L35_17150 ENOG4105JAB phenazine biosynthesis protein, phzf family B7L35_17180 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) B7L35_17195 ENOG4105D3G Pseudouridine synthase B7L35_17200 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) B7L35_17215 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) B7L35_17240 ENOG4108JPW Aminotransferase B7L35_17245 ENOG4105DY8 decarboxylase B7L35_17255 ENOG4105F7P transcriptional regulator AsnC family B7L35_17260 ENOG4107RA9 decarboxylase B7L35_17265 ENOG4105C85 amino acid B7L35_17270 ENOG4105CVA phosphate B7L35_17275 ENOG4105C8U phosphate abc transporter B7L35_17285 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) B7L35_17290 ENOG4105ERU peptidase B7L35_17305 ENOG4107QTF adenylosuccinate lyase B7L35_17325 ENOG4108Z0R Transferase B7L35_17330 ENOG4105DZ1 carboxypeptidase B7L35_17350 ENOG4108K5P (LipO)protein B7L35_17355 ENOG4105EJC lysr family transcriptional regulator B7L35_17360 ENOG4105DAN ATP-dependent protease B7L35_17375 ENOG4105DHU Bile acid B7L35_17385 ENOG41066DG (EAL) domain protein B7L35_17395 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein B7L35_17405 ENOG4105D22 carbon starvation protein B7L35_17410 ENOG4105VCD cytoplasmic protein B7L35_17450 ENOG4105C2I pirin domain protein B7L35_17460 ENOG4105WWK YheO domain protein B7L35_17475 ENOG4105CEY Amp-dependent synthetase and ligase B7L35_17490 ENOG4108IPW abc transporter atp-binding protein B7L35_17510 ENOG4105C0W non-ribosomal peptide synthetase B7L35_17515 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase B7L35_17520 ENOG4105WQI isochorismatase B7L35_17530 ENOG4105BZ1 (ABC) transporter B7L35_17535 ENOG4108JJ7 ABC transporter B7L35_17550 ENOG4105E4F Isochorismate synthase B7L35_17565 ENOG4105NX3 Membrane B7L35_17585 ENOG4105EUJ GTP cyclohydrolase i B7L35_17595 ENOG4105C7W Xanthine dehydrogenase B7L35_17625 ENOG4105CD8 aminopeptidase N B7L35_17630 ENOG4105DDQ anthranilate synthase B7L35_17640 ENOG4105DUX Transporter B7L35_17645 ENOG4105C5F glutamine synthetase B7L35_17655 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) B7L35_17690 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) B7L35_17695 ENOG4107QNR UPF0135 protein B7L35_17700 ENOG4105C0H protease B7L35_17710 ENOG4105C6K Malic enzyme B7L35_17715 ENOG4105BZU Histidine kinase B7L35_17720 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) B7L35_17725 ENOG4105SYT Methylenetetrahydrofolate reductase B7L35_17730 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) B7L35_17745 ENOG4107QPN acyl-Coa dehydrogenase B7L35_17750 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) B7L35_17755 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) B7L35_17765 ENOG4107RNU major facilitator superfamily MFS_1 B7L35_17775 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) B7L35_17780 ENOG4105CE9 30S ribosomal protein S2 B7L35_17820 ENOG4105CVE Lytic murein transglycosylase B7L35_17825 ENOG4105CNI cell division protein FtsW B7L35_17840 ENOG4105E3A (ABC) transporter B7L35_17845 ENOG4105DA5 (ABC) transporter B7L35_17875 ENOG4105ENJ RND efflux system, outer membrane lipoprotein B7L35_17885 ENOG4105ENT Efflux transporter rnd family, mfp subunit B7L35_17900 ENOG4105E89 ABC transporter B7L35_17905 ENOG4105DSP amino acid AbC transporter B7L35_17910 ENOG4106YG3 ABC transporter B7L35_17915 ENOG4108JEH abc transporter atp-binding protein B7L35_17925 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding B7L35_17930 ENOG4105CFP Peptidase U32 B7L35_17935 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family B7L35_17940 ENOG4105JAB phenazine biosynthesis protein, phzf family B7L35_17945 ENOG4105DP0 ferredoxin-NADP reductase B7L35_17950 ENOG4108R96 Methyltransferase, YaeB family B7L35_17960 ENOG4107QHF type ii secretion system protein e B7L35_17970 ENOG4105XJC Two component transcriptional regulator (Winged helix family B7L35_17975 ENOG4105DHQ Histidine kinase B7L35_17985 ENOG4105M6F mutator MutT protein B7L35_17995 ENOG4105BZ4 penicillin-binding protein B7L35_18000 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) B7L35_18005 ENOG4105VUT cytoplasmic protein B7L35_18020 ENOG4105CK2 sodium dicarboxylate symporter B7L35_18025 ENOG4105C1G acyl-Coa dehydrogenase B7L35_18035 ENOG4105CQC Prephenate dehydratase B7L35_18040 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase B7L35_18050 ENOG4105CIN aminoacyl-histidine dipeptidase B7L35_18070 ENOG4105E0Y RtcB Protein B7L35_18075 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) B7L35_18080 ENOG4105CYB regulatoR B7L35_18110 ENOG4105M08 Membrane B7L35_18115 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) B7L35_18125 ENOG4105VEQ Cold shock protein B7L35_18130 ENOG4105C1J atp-dependent rna helicase B7L35_18140 ENOG41069NU Nitroreductase B7L35_18175 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase B7L35_18190 ENOG4105C5I Dehydrogenase B7L35_18195 ENOG4105ERG peptidase m48, ste24p B7L35_18200 ENOG4105KTH gatB Yqey B7L35_18205 ENOG4105VCC 30S ribosomal protein S21 B7L35_18230 ENOG4105D9P serine threonine protein kinase B7L35_18255 ENOG4105EVZ LysR family transcriptional regulator B7L35_18260 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) B7L35_18265 ENOG4105C26 Dehydrogenase B7L35_18300 ENOG4105H4F exported protein B7L35_18330 ENOG4105D6U Sodium Glutamate Symporter B7L35_18340 ENOG4105JXH GntR family transcriptional regulator B7L35_18375 ENOG4105F1S paraquat-inducible protein a B7L35_18380 ENOG4105DY2 Paraquat-inducible protein b B7L35_18390 ENOG4105VT2 5-hydroxyisourate hydrolase B7L35_18430 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase B7L35_18440 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase B7L35_18445 ENOG4105DHQ Histidine kinase B7L35_18450 ENOG4105ETX regulatoR B7L35_18500 ENOG4105CK2 sodium dicarboxylate symporter B7L35_18510 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) B7L35_18515 ENOG4108UMI ABC transporter, permease B7L35_18520 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) B7L35_18530 ENOG4105C12 Phosphoribosylglycinamide synthetase B7L35_18535 ENOG4105DC1 bifunctional purine biosynthesis protein purh B7L35_18540 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) B7L35_18590 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) B7L35_18595 ENOG4105CDU Replicative dna helicase B7L35_18620 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) B7L35_18625 ENOG4105CCU oxidase (Subunit III) B7L35_18630 ENOG4105BZ9 Cytochrome C oxidase, subunit I B7L35_18635 ENOG4105E2S oxidase) subunit II B7L35_18660 ENOG4107BJW polysaccharide deacetylase B7L35_18665 ENOG4105CND Glycosyl transferase, family 2