locus-tag class description WP8W18E11_00020 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) WP8W18E11_00040 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) WP8W18E11_00060 ENOG4105DQR SNARE associated Golgi WP8W18E11_00070 ENOG4105C5H ABC transporter WP8W18E11_00080 ENOG4108821 RND type efflux pump WP8W18E11_00090 ENOG4108821 RND type efflux pump WP8W18E11_00100 ENOG4108821 RND type efflux pump WP8W18E11_00120 ENOG4105D74 hydrolase WP8W18E11_00130 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) WP8W18E11_00140 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) WP8W18E11_00170 ENOG4105C8J )-transporter WP8W18E11_00190 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B WP8W18E11_00240 ENOG4108W5M transcriptional regulator WP8W18E11_00250 ENOG4105C2W permease WP8W18E11_00270 ENOG4108IG5 Transcriptional regulator WP8W18E11_00280 ENOG4105DJY efflux transporter, rnd family, mfp subunit WP8W18E11_00350 ENOG4105F27 Major Facilitator WP8W18E11_00360 ENOG4105CV8 reductase WP8W18E11_00370 ENOG4105HEI LysR family (Transcriptional regulator WP8W18E11_00400 ENOG4105DQ4 alcohol dehydrogenase WP8W18E11_00410 ENOG4108R3E Dna-3-methyladenine glycosylase i WP8W18E11_00440 ENOG4105CEN a g-specific adenine glycosylase WP8W18E11_00480 ENOG4108ZZ3 UPF0260 protein WP8W18E11_00500 ENOG4105D1H recombination factor protein RarA WP8W18E11_00510 ENOG4105S64 Formate nitrite transporter WP8W18E11_00550 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) WP8W18E11_00560 ENOG4108RWI nicotinamidase WP8W18E11_00570 ENOG4105C09 Bile acid WP8W18E11_00580 ENOG4107QI1 Mate efflux family protein WP8W18E11_00590 ENOG4105EWC Purine nucleoside phosphorylase WP8W18E11_00630 ENOG4108RXX maleylacetoacetate isomerase WP8W18E11_00650 ENOG4105C85 amino acid WP8W18E11_00670 ENOG4105CKI cobalamin synthesis protein WP8W18E11_00690 ENOG4105CZE histidine utilization repressor WP8W18E11_00700 ENOG41090B9 response to stress WP8W18E11_00730 ENOG4105C85 amino acid WP8W18E11_00750 ENOG41088SP formiminoglutamate hydrolase WP8W18E11_00770 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 WP8W18E11_00780 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) WP8W18E11_00790 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) WP8W18E11_00810 ENOG4108ZAI phosphatidylglycerophosphatase a WP8W18E11_00820 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) WP8W18E11_00850 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) WP8W18E11_00940 ENOG4105KHC sulfurtransferase WP8W18E11_00970 ENOG4105BZU Histidine kinase WP8W18E11_00980 ENOG4105CK6 Two component transcriptional regulator (Winged helix family WP8W18E11_01010 ENOG4107QJQ Mate efflux family protein WP8W18E11_01020 ENOG4105CHM Aminotransferase WP8W18E11_01030 ENOG4106BRA Membrane WP8W18E11_01060 ENOG4105D9M gamma-glutamylcysteine synthetase WP8W18E11_01080 ENOG4105CS6 Rhs element vgr protein WP8W18E11_01090 ENOG4105NVB glycoside hydrolase, family 19 WP8W18E11_01130 ENOG4105IPS esterase WP8W18E11_01140 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) WP8W18E11_01150 ENOG4108Z2U ureidoglycolate hydrolase WP8W18E11_01170 ENOG41061H0 Monooxygenase WP8W18E11_01200 ENOG41084YZ Hydrolase WP8W18E11_01260 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) WP8W18E11_01270 ENOG4105BZU Histidine kinase WP8W18E11_01300 ENOG4105KUZ arsenate reductase WP8W18E11_01310 ENOG4105CGK Exodeoxyribonuclease III WP8W18E11_01360 ENOG4105D7Z glutathione synthase WP8W18E11_01400 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) WP8W18E11_01410 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) WP8W18E11_01420 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) WP8W18E11_01450 ENOG41063SB peptidase WP8W18E11_01460 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) WP8W18E11_01470 ENOG4107QSN dihydrolipoamide acetyltransferase WP8W18E11_01500 ENOG4105E0K tonB-dependent siderophore receptor WP8W18E11_01530 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) WP8W18E11_01560 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) WP8W18E11_01590 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) WP8W18E11_01620 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase WP8W18E11_01630 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase WP8W18E11_01650 ENOG4105D64 Mechanosensitive ion channel WP8W18E11_01670 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) WP8W18E11_01680 ENOG4108W2Y isochorismatase WP8W18E11_01700 ENOG4105FBW Monooxygenase WP8W18E11_01710 ENOG4108UZX fmn reductase WP8W18E11_01740 ENOG4105BZU Histidine kinase WP8W18E11_01750 ENOG41062QD Membrane WP8W18E11_01760 ENOG4107QN1 sodium solute WP8W18E11_01780 ENOG4105C94 Transporter WP8W18E11_01800 ENOG4105BZU Histidine kinase WP8W18E11_01810 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) WP8W18E11_01820 ENOG4108WUH Transcriptional regulator, TetR family WP8W18E11_01830 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein WP8W18E11_01850 ENOG4105RA2 Membrane WP8W18E11_01860 ENOG4105DWF phosphomethylpyrimidine kinase WP8W18E11_01880 ENOG4107RDB Major Facilitator WP8W18E11_01890 ENOG4108UUM single-stranded DNA-binding protein WP8W18E11_01920 ENOG4108UMN azlc family WP8W18E11_01940 ENOG4105C85 amino acid WP8W18E11_01960 ENOG4108JPW Aminotransferase WP8W18E11_01970 ENOG4105C26 Dehydrogenase WP8W18E11_01990 ENOG4105CHJ isochorismatase hydrolase WP8W18E11_02000 ENOG4105EUB pirin domain protein WP8W18E11_02040 ENOG4105D94 Major Facilitator Superfamily WP8W18E11_02050 ENOG4106NZI LysR family Transcriptional regulator WP8W18E11_02090 ENOG4105CPC Aldo Keto reductase WP8W18E11_02100 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) WP8W18E11_02130 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) WP8W18E11_02160 ENOG4105KVH Transcriptional regulator WP8W18E11_02170 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein WP8W18E11_02180 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_02190 ENOG4108V1U phospholipid-binding protein WP8W18E11_02210 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain WP8W18E11_02220 ENOG4108UQN AraC family transcriptional regulator WP8W18E11_02320 ENOG4105CUV Homoserine Kinase WP8W18E11_02400 ENOG4105BZ1 (ABC) transporter WP8W18E11_02440 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) WP8W18E11_02470 ENOG4108R6G acetyltransferase WP8W18E11_02480 ENOG4105CYC Transferase WP8W18E11_02490 ENOG4105E0F Histidine kinase WP8W18E11_02520 ENOG4105CHH sulfate transporter WP8W18E11_02530 ENOG4105PDP Short chain dehydrogenase WP8W18E11_02550 ENOG4105C5H ABC transporter WP8W18E11_02660 ENOG4108IQI permease WP8W18E11_02690 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein WP8W18E11_02720 ENOG4105CJN penicillin-binding protein WP8W18E11_02730 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) WP8W18E11_02740 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) WP8W18E11_02770 ENOG4105DHI Methyltransferase WP8W18E11_02780 ENOG4108JQC penicillin-binding protein 1A WP8W18E11_02830 ENOG4105E4G Type IV pilus WP8W18E11_02870 ENOG4105CBC glutamate synthase WP8W18E11_02880 ENOG4105BZ8 glutamate synthase WP8W18E11_02900 ENOG4108V0P LemA family WP8W18E11_02910 ENOG4105HA9 of methanol dehydrogenase type WP8W18E11_02950 ENOG4108YSG O-Antigen polymerase WP8W18E11_02960 ENOG4108UQY Iron-storage protein WP8W18E11_02980 ENOG4105KME endoribonuclease L-psp WP8W18E11_02990 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) WP8W18E11_03010 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) WP8W18E11_03110 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) WP8W18E11_03140 ENOG4107IFA Lipase (EC 3.1.1.3) WP8W18E11_03150 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) WP8W18E11_03160 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) WP8W18E11_03210 ENOG4108JQ1 Dehydrogenase WP8W18E11_03220 ENOG4105CQB FAD linked oxidase domain protein WP8W18E11_03240 ENOG4105VRH Antibiotic biosynthesis monooxygenase WP8W18E11_03250 ENOG4105NF4 modulator of drug activity WP8W18E11_03270 ENOG4107QF7 multi-drug WP8W18E11_03280 ENOG4105EM2 membrane WP8W18E11_03290 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) WP8W18E11_03300 ENOG4105IPI Membrane WP8W18E11_03370 ENOG4108IQI permease WP8W18E11_03380 ENOG4105D82 Glutamate dehydrogenase WP8W18E11_03390 ENOG4105C8Y Acetylornithine aminotransferase WP8W18E11_03410 ENOG4105C26 Dehydrogenase WP8W18E11_03540 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit WP8W18E11_03590 ENOG4105W87 Cbs domain WP8W18E11_03600 ENOG41067S9 phage shock protein C, PspC WP8W18E11_03620 ENOG4105CSU acyl-Coa dehydrogenase WP8W18E11_03650 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) WP8W18E11_03680 ENOG4105ECY inositol monophosphatase WP8W18E11_03690 ENOG4105C1J atp-dependent rna helicase WP8W18E11_03710 ENOG4105DHJ ABC, transporter WP8W18E11_03720 ENOG4105CY3 ABC transporter, permease WP8W18E11_03740 ENOG4105E3I toluene tolerance WP8W18E11_03760 ENOG4105D7N magnesium and cobalt transport protein CorA WP8W18E11_03770 ENOG4108URH decarboxylase WP8W18E11_03790 ENOG4105MJ2 Competence protein WP8W18E11_03800 ENOG4105CB5 ATP-dependent DNA helicase recG WP8W18E11_03840 ENOG4105C29 acyl-CoA thioesterase WP8W18E11_03850 ENOG4105CK2 sodium dicarboxylate symporter WP8W18E11_03880 ENOG4105KPV Transcriptional regulator WP8W18E11_03900 ENOG4105D7A ATP-binding protein WP8W18E11_03920 ENOG41089BK Glutamine amido-transferase WP8W18E11_04140 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) WP8W18E11_04220 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_04300 ENOG4105VKU nucleicacid-binding protein WP8W18E11_04310 ENOG4105DGW oligopeptidase A WP8W18E11_04320 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) WP8W18E11_04370 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase WP8W18E11_04380 ENOG4108K2B transcriptional regulator WP8W18E11_04400 ENOG4107S2Z UPF0761 membrane protein WP8W18E11_04410 ENOG4105CS1 NAD(P)H quinone oxidoreductase WP8W18E11_04470 ENOG4105C9A Phoh family WP8W18E11_04490 ENOG4105E4C Lytic transglycosylase catalytic WP8W18E11_04550 ENOG4105D6S protein involved in catabolism of external DNA WP8W18E11_04560 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase WP8W18E11_04600 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_04610 ENOG4108RZE Tetr family transcriptional regulator WP8W18E11_04640 ENOG4107QX3 carboxylase WP8W18E11_04650 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_04690 ENOG4105KB2 stringent starvation protein b WP8W18E11_04700 ENOG4107MKT Stringent starvation protein a WP8W18E11_04710 ENOG4108UJD 30S ribosomal protein S9 WP8W18E11_04730 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) WP8W18E11_04740 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) WP8W18E11_04750 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) WP8W18E11_04790 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) WP8W18E11_04810 ENOG4107RZC phospholipase d WP8W18E11_04830 ENOG4105UYK outer membrane protein a WP8W18E11_04840 ENOG4108KHX Diguanylate cyclase WP8W18E11_04860 ENOG4107QN2 dihydrolipoyl dehydrogenase WP8W18E11_04890 ENOG4107U2T alpha beta WP8W18E11_04910 ENOG4105NAU thioesterase Superfamily protein WP8W18E11_04970 ENOG4105K9H YciI-like protein WP8W18E11_04990 ENOG4105DB7 PHP domain protein WP8W18E11_05000 ENOG4105FFC UPF0187 protein WP8W18E11_05020 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase WP8W18E11_05030 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) WP8W18E11_05040 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) WP8W18E11_05050 ENOG4105VIE preprotein translocase, subunit YajC WP8W18E11_05160 ENOG4105BZU Histidine kinase WP8W18E11_05170 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) WP8W18E11_05180 ENOG4105CM2 brancheD-chain amino acid aminotransferase WP8W18E11_05200 ENOG4107BJW polysaccharide deacetylase WP8W18E11_05210 ENOG4107TYR Glycosyl Transferase WP8W18E11_05230 ENOG4105C1B dTDP-glucose 4-6-dehydratase WP8W18E11_05240 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase WP8W18E11_05260 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase WP8W18E11_05320 ENOG4105UGU tonB-dependent Receptor WP8W18E11_05360 ENOG4108VY7 phosphate-starvation-inducible protein PsiE WP8W18E11_05370 ENOG4105CSU acyl-Coa dehydrogenase WP8W18E11_05380 ENOG4105CSU acyl-Coa dehydrogenase WP8W18E11_05400 ENOG4105EB3 Histidine kinase WP8W18E11_05410 ENOG4105E3W Two component transcriptional regulator (Winged helix family WP8W18E11_05420 ENOG4105CNG UPF0061 protein WP8W18E11_05460 ENOG4108WBT adenosyltransferase WP8W18E11_05470 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) WP8W18E11_05560 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase WP8W18E11_05600 ENOG4105D3R alkyl hydroperoxide reductase WP8W18E11_05630 ENOG4105CSH Transporter WP8W18E11_05640 ENOG4108UT2 hemolysin iii WP8W18E11_05700 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_05710 ENOG4108R6W Transcriptional regulator, ARAC family WP8W18E11_05730 ENOG4105TW1 Carbohydrate-selective porin OprB WP8W18E11_05740 ENOG4105DZG Dehydrogenase WP8W18E11_05750 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) WP8W18E11_05790 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_05810 ENOG4108WHA ompa motb domain protein WP8W18E11_05830 ENOG4105E0Y RtcB Protein WP8W18E11_05840 ENOG4108IQI permease WP8W18E11_05860 ENOG4105C2W permease WP8W18E11_05870 ENOG4105CI3 gtp-binding protein typa WP8W18E11_05900 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) WP8W18E11_05920 ENOG4108VX5 3-methyladenine DNA glycosylase WP8W18E11_05930 ENOG4105CHB tonB-dependent Receptor WP8W18E11_05940 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase WP8W18E11_05950 ENOG4108N2Y auxin Efflux WP8W18E11_05970 ENOG4105T95 Thiol disulfide interChange protein WP8W18E11_05980 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) WP8W18E11_06000 ENOG4105K78 MarR family Transcriptional regulator WP8W18E11_06010 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA WP8W18E11_06020 ENOG4105KWI UPF0339 protein WP8W18E11_06070 ENOG4108UNF response regulator WP8W18E11_06080 ENOG4105M3Z response regulator WP8W18E11_06090 ENOG4108ZGA chew protein WP8W18E11_06100 ENOG4105C8Q Methyl-accepting chemotaxis WP8W18E11_06110 ENOG4105CBS Chea signal transduction histidine kinase WP8W18E11_06150 ENOG4107PEH Entericidin EcnA/B family WP8W18E11_06170 ENOG4105WD1 Membrane WP8W18E11_06180 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein WP8W18E11_06220 ENOG4105EM2 membrane WP8W18E11_06230 ENOG4105C2C drug resistance transporter, Bcr CflA WP8W18E11_06260 ENOG4105BZG amino acid carrier protein WP8W18E11_06270 ENOG4105D78 K07001 NTE family protein WP8W18E11_06280 ENOG4105C7B Threonine dehydratase WP8W18E11_06300 ENOG4105C9K Endothelin-converting enzyme 1 WP8W18E11_06350 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) WP8W18E11_06370 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) WP8W18E11_06390 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) WP8W18E11_06400 ENOG4105VQ7 Rod shape-determining protein MreD WP8W18E11_06410 ENOG4108Z03 MAF-like protein WP8W18E11_06420 ENOG4105C03 ribonuclease WP8W18E11_06440 ENOG4105D8T Acyltransferase WP8W18E11_06460 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein WP8W18E11_06480 ENOG4108X0B nad(p)h dehydrogenase (quinone) WP8W18E11_06530 ENOG4105CF7 AraC family transcriptional regulator WP8W18E11_06560 ENOG4105C85 amino acid WP8W18E11_06570 ENOG4105C7F AcnD-accessory protein PrpF WP8W18E11_06580 ENOG4105CTB Polyprenyl synthetase WP8W18E11_06590 ENOG4105MSB protein, conserved in bacteria WP8W18E11_06620 ENOG4105D78 K07001 NTE family protein WP8W18E11_06660 ENOG4105DIJ Phosphoethanolamine transferase WP8W18E11_06670 ENOG4105XJC Two component transcriptional regulator (Winged helix family WP8W18E11_06680 ENOG4105DHQ Histidine kinase WP8W18E11_06710 ENOG4108M0I Transcriptional regulator WP8W18E11_06750 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) WP8W18E11_06790 ENOG4105K8R UPF0145 protein WP8W18E11_06800 ENOG4105K8R UPF0145 protein WP8W18E11_06810 ENOG4105ENJ RND efflux system, outer membrane lipoprotein WP8W18E11_06820 ENOG4105BZS acriflavin resistance protein WP8W18E11_06830 ENOG4105C1P efflux transporter, rnd family, mfp subunit WP8W18E11_06840 ENOG410841Q phosphoesterase PA-phosphatase related protein WP8W18E11_06890 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) WP8W18E11_06920 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) WP8W18E11_06930 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) WP8W18E11_06940 ENOG4105KVH Transcriptional regulator WP8W18E11_06960 ENOG4105CUB amino acid WP8W18E11_06990 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) WP8W18E11_07000 ENOG41084BA UPF0250 protein WP8W18E11_07010 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) WP8W18E11_07080 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit WP8W18E11_07090 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein WP8W18E11_07110 ENOG4105E33 succinate dehydrogenase WP8W18E11_07120 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 WP8W18E11_07130 ENOG4105C7S Dehydrogenase WP8W18E11_07140 ENOG4107QN2 dihydrolipoyl dehydrogenase WP8W18E11_07160 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha WP8W18E11_07180 ENOG4105CKW Inner membrane protein yedI WP8W18E11_07190 ENOG4105CGZ zinc metallopeptidase WP8W18E11_07200 ENOG4105EEQ Na H antiporter WP8W18E11_07240 ENOG4105PNM synthesis protein WP8W18E11_07270 ENOG41080TK Universal stress protein WP8W18E11_07290 ENOG4108UQ8 endoribonuclease L-psp WP8W18E11_07300 ENOG4108IG5 Transcriptional regulator WP8W18E11_07320 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain WP8W18E11_07330 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain WP8W18E11_07360 ENOG4105HBR Rna-binding protein WP8W18E11_07380 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) WP8W18E11_07390 ENOG4105EEI dihydropteroate synthase WP8W18E11_07460 ENOG4105CSH Transporter WP8W18E11_07470 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) WP8W18E11_07480 ENOG4105C6V Glycerol-3-phosphate dehydrogenase WP8W18E11_07510 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) WP8W18E11_07540 ENOG41080IJ Diacylglycerol kinase WP8W18E11_07560 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase WP8W18E11_07570 ENOG4105BZS acriflavin resistance protein WP8W18E11_07600 ENOG4105E4C Lytic transglycosylase catalytic WP8W18E11_07640 ENOG4108RRZ Transcription elongation factor GreB WP8W18E11_07660 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_07680 ENOG4105YCT UPF0386 protein WP8W18E11_07850 ENOG4105BZW Glycerate kinase WP8W18E11_07860 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit WP8W18E11_07870 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) WP8W18E11_07900 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) WP8W18E11_07920 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) WP8W18E11_07930 ENOG4105C85 amino acid WP8W18E11_07950 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) WP8W18E11_07970 ENOG4105N14 lysine exporter protein LysE YggA WP8W18E11_07980 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) WP8W18E11_07990 ENOG4105BZJ Electron transfer flavoprotein WP8W18E11_08000 ENOG4105C10 Electron transfer flavoprotein WP8W18E11_08010 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) WP8W18E11_08080 ENOG4107KET secretion protein, HlyD family WP8W18E11_08150 ENOG4105D60 lipoprotein releasing system transmembrane protein WP8W18E11_08160 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) WP8W18E11_08170 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 WP8W18E11_08190 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) WP8W18E11_08200 ENOG4107R6F Alpha Beta Hydrolase Fold protein WP8W18E11_08210 ENOG4108V3E phosphoribosylglycinamide formyltransferase WP8W18E11_08230 ENOG4105C02 permease WP8W18E11_08330 ENOG4105KCK Peptidoglycan-associated lipoprotein WP8W18E11_08340 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) WP8W18E11_08360 ENOG4105M8F Biopolymer transport protein exbD tolR WP8W18E11_08370 ENOG4105E02 MotA TolQ exbB proton channel WP8W18E11_08380 ENOG4107YD3 Thioesterase WP8W18E11_08390 ENOG4105CH2 amidohydrolase WP8W18E11_08430 ENOG4108ETH Formylglycinamide ribotide synthetase WP8W18E11_08440 ENOG4105C2C drug resistance transporter, Bcr CflA WP8W18E11_08460 ENOG4108UKI Enoyl-CoA hydratase WP8W18E11_08490 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen WP8W18E11_08520 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) WP8W18E11_08530 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) WP8W18E11_08560 ENOG4107R11 Transcriptional regulator WP8W18E11_08570 ENOG4108IJ6 ABC transporter WP8W18E11_08590 ENOG4108I5D sulfate abc transporter WP8W18E11_08610 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein WP8W18E11_08620 ENOG4105YAZ 4-amino-4-deoxychorismate lyase WP8W18E11_08630 ENOG4105HHA aminodeoxychorismate lyase WP8W18E11_08660 ENOG4108IYU L-aspartate oxidase WP8W18E11_08670 ENOG4105C0H protease WP8W18E11_08690 ENOG41068WN WP8W18E11_08710 ENOG4105C3F Signal peptidase i WP8W18E11_08740 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) WP8W18E11_08760 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) WP8W18E11_08770 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) WP8W18E11_08780 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase WP8W18E11_08790 ENOG4105EMU Dehydrogenase WP8W18E11_08830 ENOG4105F7F Chaperone WP8W18E11_08870 ENOG4105BZU Histidine kinase WP8W18E11_08890 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) WP8W18E11_08910 ENOG4105DTR rard protein WP8W18E11_08980 ENOG4107QS8 (LipO)protein WP8W18E11_08990 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) WP8W18E11_09000 ENOG4105EA8 2-Nitropropane dioxygenase WP8W18E11_09060 ENOG4107R8N Glycosyl transferase, family 2 WP8W18E11_09090 ENOG4105CVP deoxyribo-dipyrimidine photolyase WP8W18E11_09100 ENOG4108YZY peptidylprolyl cis-trans isomerase WP8W18E11_09110 ENOG4105CEP NADH dehydrogenase WP8W18E11_09120 ENOG4105DZ1 carboxypeptidase WP8W18E11_09140 ENOG4105E9K Isocitrate dehydrogenase WP8W18E11_09150 ENOG4108R99 pseudouridine synthase WP8W18E11_09200 ENOG4105CBP Major Facilitator WP8W18E11_09210 ENOG4105EGI Transcriptional regulator WP8W18E11_09220 ENOG4108ETY sodium dicarboxylate symporter WP8W18E11_09230 ENOG4105JAB phenazine biosynthesis protein, phzf family WP8W18E11_09290 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) WP8W18E11_09320 ENOG4105D3G Pseudouridine synthase WP8W18E11_09330 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) WP8W18E11_09360 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) WP8W18E11_09380 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein WP8W18E11_09410 ENOG4108JPW Aminotransferase WP8W18E11_09420 ENOG4105DY8 decarboxylase WP8W18E11_09440 ENOG4105F7P transcriptional regulator AsnC family WP8W18E11_09450 ENOG4107RA9 decarboxylase WP8W18E11_09460 ENOG4105C85 amino acid WP8W18E11_09470 ENOG4105CVA phosphate WP8W18E11_09480 ENOG4105C8U phosphate abc transporter WP8W18E11_09500 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_09510 ENOG4105ERU peptidase WP8W18E11_09540 ENOG4107QTF adenylosuccinate lyase WP8W18E11_09580 ENOG4108Z0R Transferase WP8W18E11_09590 ENOG4105DZ1 carboxypeptidase WP8W18E11_09630 ENOG4108K5P (LipO)protein WP8W18E11_09640 ENOG4105EJC lysr family transcriptional regulator WP8W18E11_09650 ENOG4105DAN ATP-dependent protease WP8W18E11_09680 ENOG4105DHU Bile acid WP8W18E11_09700 ENOG41066DG (EAL) domain protein WP8W18E11_09720 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein WP8W18E11_09740 ENOG4105D22 carbon starvation protein WP8W18E11_09750 ENOG4105VCD cytoplasmic protein WP8W18E11_09820 ENOG4105CHJ isochorismatase hydrolase WP8W18E11_09830 ENOG4105CR8 Transcriptional regulator WP8W18E11_09850 ENOG4107RN6 Monooxygenase WP8W18E11_09860 ENOG4105D74 hydrolase WP8W18E11_09950 ENOG4105C2I pirin domain protein WP8W18E11_09970 ENOG4105WWK YheO domain protein WP8W18E11_10000 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_10050 ENOG4108IPW abc transporter atp-binding protein WP8W18E11_10090 ENOG4105C0W non-ribosomal peptide synthetase WP8W18E11_10100 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase WP8W18E11_10110 ENOG4105WQI isochorismatase WP8W18E11_10140 ENOG4105BZ1 (ABC) transporter WP8W18E11_10210 ENOG4105NX3 Membrane WP8W18E11_10250 ENOG4105EUJ GTP cyclohydrolase i WP8W18E11_10270 ENOG4105C7W Xanthine dehydrogenase WP8W18E11_10330 ENOG4105CD8 aminopeptidase N WP8W18E11_10340 ENOG4105DDQ anthranilate synthase WP8W18E11_10360 ENOG4105DUX Transporter WP8W18E11_10390 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) WP8W18E11_10430 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) WP8W18E11_10440 ENOG4107QNR UPF0135 protein WP8W18E11_10450 ENOG4105C0H protease WP8W18E11_10470 ENOG4105C6K Malic enzyme WP8W18E11_10480 ENOG4105BZU Histidine kinase WP8W18E11_10490 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) WP8W18E11_10500 ENOG4105SYT Methylenetetrahydrofolate reductase WP8W18E11_10510 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) WP8W18E11_10540 ENOG4107QPN acyl-Coa dehydrogenase WP8W18E11_10550 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) WP8W18E11_10560 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) WP8W18E11_10590 ENOG4107RNU major facilitator superfamily MFS_1 WP8W18E11_10610 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) WP8W18E11_10620 ENOG4105CE9 30S ribosomal protein S2 WP8W18E11_10710 ENOG4105CVE Lytic murein transglycosylase WP8W18E11_10720 ENOG4105CNI cell division protein FtsW WP8W18E11_10750 ENOG4105E3A (ABC) transporter WP8W18E11_10760 ENOG4105DA5 (ABC) transporter WP8W18E11_10810 ENOG4105ENJ RND efflux system, outer membrane lipoprotein WP8W18E11_10830 ENOG4105ENT Efflux transporter rnd family, mfp subunit WP8W18E11_10850 ENOG4105E89 ABC transporter WP8W18E11_10860 ENOG4105DSP amino acid AbC transporter WP8W18E11_10870 ENOG4106YG3 ABC transporter WP8W18E11_10880 ENOG4108JEH abc transporter atp-binding protein WP8W18E11_10900 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding WP8W18E11_10910 ENOG4105CFP Peptidase U32 WP8W18E11_10920 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family WP8W18E11_10930 ENOG4105JAB phenazine biosynthesis protein, phzf family WP8W18E11_10940 ENOG4105JAB phenazine biosynthesis protein, phzf family WP8W18E11_10950 ENOG4105DP0 ferredoxin-NADP reductase WP8W18E11_10960 ENOG4108R96 Methyltransferase, YaeB family WP8W18E11_10980 ENOG4107QHF type ii secretion system protein e WP8W18E11_11000 ENOG4105XJC Two component transcriptional regulator (Winged helix family WP8W18E11_11010 ENOG4105DHQ Histidine kinase WP8W18E11_11030 ENOG4105M6F mutator MutT protein WP8W18E11_11050 ENOG4105BZ4 penicillin-binding protein WP8W18E11_11060 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) WP8W18E11_11070 ENOG4105VUT cytoplasmic protein WP8W18E11_11080 ENOG4108I0Q anthranilate phosphoribosyltransferase WP8W18E11_11090 ENOG4105CK2 sodium dicarboxylate symporter WP8W18E11_11100 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_11110 ENOG4105NIV Esterase WP8W18E11_11120 ENOG4105CQC Prephenate dehydratase WP8W18E11_11130 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase WP8W18E11_11150 ENOG4105CIN aminoacyl-histidine dipeptidase WP8W18E11_11190 ENOG4105E0Y RtcB Protein WP8W18E11_11200 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) WP8W18E11_11210 ENOG4105CYB regulatoR WP8W18E11_11270 ENOG4105M08 Membrane WP8W18E11_11280 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) WP8W18E11_11300 ENOG4105VEQ Cold shock protein WP8W18E11_11310 ENOG4105C1J atp-dependent rna helicase WP8W18E11_11330 ENOG41069NU Nitroreductase WP8W18E11_11400 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase WP8W18E11_11430 ENOG4105C5I Dehydrogenase WP8W18E11_11440 ENOG4105ERG peptidase m48, ste24p WP8W18E11_11450 ENOG4105KTH gatB Yqey WP8W18E11_11510 ENOG4105D9P serine threonine protein kinase WP8W18E11_11520 ENOG4105EVZ LysR family transcriptional regulator WP8W18E11_11530 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) WP8W18E11_11540 ENOG4105C26 Dehydrogenase WP8W18E11_11610 ENOG4105H4F exported protein WP8W18E11_11670 ENOG4105D6U Sodium Glutamate Symporter WP8W18E11_11690 ENOG4105JXH GntR family transcriptional regulator WP8W18E11_11790 ENOG4105CSH Transporter WP8W18E11_11860 ENOG4105F1S paraquat-inducible protein a WP8W18E11_11870 ENOG4105DY2 Paraquat-inducible protein b WP8W18E11_11980 ENOG4105CK2 sodium dicarboxylate symporter WP8W18E11_12000 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) WP8W18E11_12010 ENOG4108UMI ABC transporter, permease WP8W18E11_12020 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_12040 ENOG4105C12 Phosphoribosylglycinamide synthetase WP8W18E11_12050 ENOG4105DC1 bifunctional purine biosynthesis protein purh WP8W18E11_12060 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) WP8W18E11_12160 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) WP8W18E11_12170 ENOG4105CDU Replicative dna helicase WP8W18E11_12220 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) WP8W18E11_12230 ENOG4105CCU oxidase (Subunit III) WP8W18E11_12240 ENOG4105BZ9 Cytochrome C oxidase, subunit I WP8W18E11_12250 ENOG4105E2S oxidase) subunit II WP8W18E11_12300 ENOG4107BJW polysaccharide deacetylase WP8W18E11_12310 ENOG4105CND Glycosyl transferase, family 2 WP8W18E11_12320 ENOG4105CND Glycosyl transferase, family 2 WP8W18E11_12350 ENOG4105DEN Luciferase family WP8W18E11_12380 ENOG4105CC0 LysR family Transcriptional regulator WP8W18E11_12410 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) WP8W18E11_12440 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_12460 ENOG4108MEJ flavin reductase domain protein WP8W18E11_12470 ENOG4105D06 uba thif-type nad fad binding protein WP8W18E11_12490 ENOG4105KRF dihydroneopterin aldolase WP8W18E11_12520 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) WP8W18E11_12530 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) WP8W18E11_12540 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) WP8W18E11_12550 ENOG4105C08 Histidine kinase WP8W18E11_12560 ENOG4105EEX Two component transcriptional regulator (Winged helix family WP8W18E11_12570 ENOG4105CFQ glutamine synthetase WP8W18E11_12600 ENOG4107S74 Lysophospholipid transporter LplT WP8W18E11_12610 ENOG4105CFU surface antigen WP8W18E11_12640 ENOG4107QIJ Aconitate hydratase 2 WP8W18E11_12660 ENOG4105EYW Ion transport protein WP8W18E11_12670 ENOG4105F27 Major Facilitator WP8W18E11_12700 ENOG4105DZ2 Transcriptional regulator WP8W18E11_12770 ENOG4105K8N protein family UPF0079, ATPase WP8W18E11_12780 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) WP8W18E11_12800 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) WP8W18E11_12810 ENOG4108TZV Membrane WP8W18E11_12820 ENOG4108RCM Nitroreductase WP8W18E11_12860 ENOG4105CX6 glutaminyL-tRNA synthetase WP8W18E11_12870 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) WP8W18E11_12880 ENOG4107FQ9 ethanolamine ammonia-lyase WP8W18E11_12890 ENOG4105CPD ethanolamine ammonia-lyase WP8W18E11_12900 ENOG4107R55 ethanolamine transporter WP8W18E11_12920 ENOG4107RR1 TRANSCRIPTIONal WP8W18E11_12940 ENOG4105C0A alcohol dehydrogenase WP8W18E11_12950 ENOG4107QUV Domain protein WP8W18E11_13000 ENOG4105CD8 aminopeptidase N WP8W18E11_13040 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) WP8W18E11_13050 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_13090 ENOG4105R8C Transcriptional regulator WP8W18E11_13140 ENOG4105CUY Mechanosensitive ion channel WP8W18E11_13200 ENOG4105CNM Receptor WP8W18E11_13240 ENOG4105C5H ABC transporter WP8W18E11_13250 ENOG41081QV Universal stress protein WP8W18E11_13300 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic WP8W18E11_13320 ENOG4105DKK Benzoate WP8W18E11_13330 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_13340 ENOG4108NIW Leucine export protein LeuE WP8W18E11_13360 ENOG4105C5Q Transcriptional regulator WP8W18E11_13380 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_13390 ENOG4105CHR reductase WP8W18E11_13440 ENOG4107QMP dna polymerase iii subunits gamma and tau WP8W18E11_13460 ENOG4105HSS phospholipase C WP8W18E11_13480 ENOG4105C0A alcohol dehydrogenase WP8W18E11_13540 ENOG4105CBC glutamate synthase WP8W18E11_13560 ENOG4105ESI atpase involved in dna repair WP8W18E11_13570 ENOG4105CB5 ATP-dependent DNA helicase recG WP8W18E11_13610 ENOG4105D8G Major Facilitator superfamily WP8W18E11_13630 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase WP8W18E11_13640 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein WP8W18E11_13680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family WP8W18E11_13700 ENOG4107QZF nitrite reductase NADPH large subunit WP8W18E11_13710 ENOG4108IFG nitrite reductase, (NAD(P)H) WP8W18E11_13780 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) WP8W18E11_13790 ENOG4105CVM Molybdenum cofactor synthesis domain protein WP8W18E11_13810 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family WP8W18E11_13820 ENOG4105T38 integral membrane protein WP8W18E11_13860 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) WP8W18E11_13870 ENOG4105CMR udp-glucose 4-epimerase WP8W18E11_13980 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family WP8W18E11_13990 ENOG4105CUX Signal transduction histidine kinase WP8W18E11_14030 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) WP8W18E11_14040 ENOG4105KNE Phosphatidate cytidylyltransferase WP8W18E11_14060 ENOG4105DZP Membrane-associated zinc metalloprotease WP8W18E11_14070 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane WP8W18E11_14110 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) WP8W18E11_14130 ENOG4105Y3E Modulates RecA activity (By similarity) WP8W18E11_14150 ENOG4105VEJ Heat shock protein WP8W18E11_14160 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 WP8W18E11_14210 ENOG4105F7P transcriptional regulator AsnC family WP8W18E11_14230 ENOG4105C85 amino acid WP8W18E11_14260 ENOG4105CHH sulfate transporter WP8W18E11_14270 ENOG4108RAV Conserved protein WP8W18E11_14280 ENOG4105D8V Glucose sorbosone dehydrogenase WP8W18E11_14300 ENOG4105BZU Histidine kinase WP8W18E11_14340 ENOG4105DM4 PTS System WP8W18E11_14350 ENOG4105DE4 1-phosphofructokinase WP8W18E11_14360 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) WP8W18E11_14410 ENOG4105CWM branched-chain amino acid transport system II carrier protein WP8W18E11_14420 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) WP8W18E11_14430 ENOG4105CC0 LysR family Transcriptional regulator WP8W18E11_14450 ENOG4105M2J Glutaredoxin WP8W18E11_14460 ENOG4105C8Y Acetylornithine aminotransferase WP8W18E11_14470 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) WP8W18E11_14520 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) WP8W18E11_14540 ENOG41068P6 UPF0319 protein WP8W18E11_14580 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii WP8W18E11_14590 ENOG4105C4M (Ubiquinol oxidase) subunit I WP8W18E11_14610 ENOG4105PV3 Inner membrane protein yqiJ WP8W18E11_14640 ENOG4105E0K tonB-dependent siderophore receptor WP8W18E11_14660 ENOG4105HDD phospholipase WP8W18E11_14670 ENOG4105CZN Potassium uptake protein WP8W18E11_14690 ENOG4105C7B Threonine dehydratase WP8W18E11_14750 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) WP8W18E11_14760 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit WP8W18E11_14780 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) WP8W18E11_14810 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase WP8W18E11_14900 ENOG4107VMU Membrane WP8W18E11_14910 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) WP8W18E11_14930 ENOG4107QP7 CoA-transferase subunit A WP8W18E11_14940 ENOG4107QNJ CoA-transferase subunit B WP8W18E11_14950 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_14960 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase WP8W18E11_14970 ENOG4105F2Z 3-oxoadipate enol-lactonase WP8W18E11_14980 ENOG4105D2S major facilitator superfamily WP8W18E11_14990 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase WP8W18E11_15000 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta WP8W18E11_15010 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha WP8W18E11_15020 ENOG4105FF2 Type I DHQase WP8W18E11_15030 ENOG4106JPM 3-dehydroshikimate dehydratase WP8W18E11_15040 ENOG4105TW1 Carbohydrate-selective porin OprB WP8W18E11_15050 ENOG4105DZG Dehydrogenase WP8W18E11_15070 ENOG4105MD1 YeeE YedE family protein WP8W18E11_15100 ENOG4107HP6 Transcriptional regulator WP8W18E11_15110 ENOG4108PTX LysR family Transcriptional regulator WP8W18E11_15120 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_15170 ENOG4105DNH Major Facilitator WP8W18E11_15190 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) WP8W18E11_15230 ENOG4105FUY alpha subunit WP8W18E11_15250 ENOG4105CHR reductase WP8W18E11_15290 ENOG4105F11 amine oxidase WP8W18E11_15310 ENOG4105C26 Dehydrogenase WP8W18E11_15330 ENOG4105F2Z 3-oxoadipate enol-lactonase WP8W18E11_15340 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_15350 ENOG4107QNJ CoA-transferase subunit B WP8W18E11_15360 ENOG4107QP7 CoA-transferase subunit A WP8W18E11_15380 ENOG4105NN7 muconolactone delta-isomerase WP8W18E11_15390 ENOG4105DTQ mandelate racemase muconate lactonizing WP8W18E11_15400 ENOG4108KB2 LysR family Transcriptional regulator WP8W18E11_15420 ENOG4107EJG GntR family transcriptional regulator WP8W18E11_15460 ENOG4105CZJ Aldehyde dehydrogenase WP8W18E11_15490 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase WP8W18E11_15510 ENOG4105NAE bifunctional deaminase-reductase domain protein WP8W18E11_15530 ENOG4108Z6Z Transcriptional regulator WP8W18E11_15580 ENOG4107Z3H Transcriptional regulator, TetR family WP8W18E11_15590 ENOG4108PTX LysR family Transcriptional regulator WP8W18E11_15600 ENOG41061TZ Short-chain dehydrogenase reductase Sdr WP8W18E11_15610 ENOG41061TZ Short-chain dehydrogenase reductase Sdr WP8W18E11_15620 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr WP8W18E11_15640 ENOG4105CSU acyl-Coa dehydrogenase WP8W18E11_15660 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_15850 ENOG4106P55 Transcriptional regulator WP8W18E11_15880 ENOG4105CW7 secretion protein, HlyD family WP8W18E11_15910 ENOG4105CZJ Aldehyde dehydrogenase WP8W18E11_15940 ENOG4105DDW LysR family Transcriptional regulator WP8W18E11_15950 ENOG4105EXW epimerase dehydratase WP8W18E11_15970 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase WP8W18E11_15980 ENOG4105CF7 AraC family transcriptional regulator WP8W18E11_15990 ENOG4105DQ4 alcohol dehydrogenase WP8W18E11_16010 ENOG4105EHG Permease protein WP8W18E11_16020 ENOG4105E0A ABC, transporter WP8W18E11_16060 ENOG4105C5T Phosphoribosyl pyrophosphate synthase WP8W18E11_16220 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) WP8W18E11_16290 ENOG4105M03 Domain of unknown function (DUF955) WP8W18E11_16390 ENOG4108R6W Transcriptional regulator, ARAC family WP8W18E11_16400 ENOG4108821 RND type efflux pump WP8W18E11_16420 ENOG4105E0F Histidine kinase WP8W18E11_16430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family WP8W18E11_16440 ENOG4105C1P efflux transporter, rnd family, mfp subunit WP8W18E11_16450 ENOG4105BZS acriflavin resistance protein WP8W18E11_16510 ENOG4105X0I Fimbrial WP8W18E11_16630 ENOG4107RZC phospholipase d WP8W18E11_16670 ENOG4108IGT Dipeptidase WP8W18E11_16730 ENOG4107T31 5'-nucleotidase WP8W18E11_16750 ENOG4105WQI isochorismatase WP8W18E11_16760 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase WP8W18E11_16770 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_16780 ENOG4105E0C molybdate abc transporter WP8W18E11_16790 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein WP8W18E11_16800 ENOG4105F4R Transcriptional regulator mode WP8W18E11_16810 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit WP8W18E11_16820 ENOG4108YS2 small subunit WP8W18E11_16830 ENOG4105F57 Anthranilate dioxygenase reductase WP8W18E11_16880 ENOG4105CHR reductase WP8W18E11_16900 ENOG4105D2S major facilitator superfamily WP8W18E11_16910 ENOG4105CF7 AraC family transcriptional regulator WP8W18E11_16920 ENOG4105DTD Dehydrogenase WP8W18E11_16930 ENOG4105CY2 Citrate transporter WP8W18E11_16950 ENOG4108IND Tetr family transcriptional regulator WP8W18E11_17000 ENOG4108M0I Transcriptional regulator WP8W18E11_17030 ENOG4105CRW Short chain fatty acid transporter WP8W18E11_17040 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_17060 ENOG4107YNJ LysR family Transcriptional regulator WP8W18E11_17090 ENOG4108IJ0 Aspartate ammonia-lyase WP8W18E11_17110 ENOG4105CSH Transporter WP8W18E11_17150 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component WP8W18E11_17160 ENOG4106FTQ Taurine ABC transporter, periplasmic WP8W18E11_17210 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) WP8W18E11_17220 ENOG4105KVH Transcriptional regulator WP8W18E11_17230 ENOG4105UEI Transcriptional Regulator AraC Family WP8W18E11_17260 ENOG4108VCT Sulfite exporter TauE/SafE WP8W18E11_17280 ENOG4107S76 domain protein WP8W18E11_17300 ENOG4105FFC UPF0187 protein WP8W18E11_17320 ENOG4105CHR reductase WP8W18E11_17350 ENOG4105CPP Dehydrogenase, E1 component WP8W18E11_17360 ENOG4107R0V Pyruvate dehydrogenase WP8W18E11_17370 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) WP8W18E11_17400 ENOG4105BZU Histidine kinase WP8W18E11_17420 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) WP8W18E11_17430 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) WP8W18E11_17450 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) WP8W18E11_17510 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) WP8W18E11_17520 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) WP8W18E11_17550 ENOG4105C28 cystathionine WP8W18E11_17570 ENOG4105F2W methyltransferase WP8W18E11_17630 ENOG4105K59 histidine triad (HIT) protein WP8W18E11_17680 ENOG4107QWP ABC-2 type transporter WP8W18E11_17690 ENOG4107QWP ABC-2 type transporter WP8W18E11_17700 ENOG4105CJ1 ABC, transporter WP8W18E11_17730 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) WP8W18E11_17740 ENOG4105CNM Receptor WP8W18E11_17780 ENOG4107TSN permease WP8W18E11_17790 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) WP8W18E11_17820 ENOG4107TB6 phosphoglycerate mutase WP8W18E11_17830 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) WP8W18E11_17840 ENOG4108YZT Adenosylcobinamide kinase WP8W18E11_17860 ENOG4107VXZ Hydrolase WP8W18E11_17920 ENOG4105JSC dimethylmenaquinone methyltransferase WP8W18E11_17940 ENOG4105DJU Siderophore biosynthesis protein WP8W18E11_17950 ENOG4105DUU IucA IucC family protein WP8W18E11_17960 ENOG4105C0R drug resistance transporter emrb qaca subfamily WP8W18E11_17990 ENOG4108Z66 YbaK ebsC protein WP8W18E11_18020 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_18030 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_18040 ENOG4105EEF Alkane 1-monooxygenase WP8W18E11_18050 ENOG4105E7U AraC family transcriptional regulator WP8W18E11_18060 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) WP8W18E11_18070 ENOG4105K70 DNA-binding protein WP8W18E11_18100 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family WP8W18E11_18120 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins WP8W18E11_18130 ENOG4108Z4V iron-sulfur cluster assembly WP8W18E11_18160 ENOG4108ZIT Ferredoxin, 2FE-2S WP8W18E11_18170 ENOG4105F8J Adenylate Guanylate cyclase WP8W18E11_18190 ENOG4108JA2 transcriptioN-repair coupling factor WP8W18E11_18230 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) WP8W18E11_18240 ENOG4105K4T epimerase WP8W18E11_18270 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase WP8W18E11_18310 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component WP8W18E11_18330 ENOG4105DGW oligopeptidase A WP8W18E11_18410 ENOG4105SG9 biopolymer transport protein, ExbD WP8W18E11_18430 ENOG4107QP3 malate synthase g WP8W18E11_18440 ENOG4105D6Z AFG1 family ATPase WP8W18E11_18460 ENOG4107RN6 Monooxygenase WP8W18E11_18500 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) WP8W18E11_18510 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) WP8W18E11_18540 ENOG4108Z6B deaminase WP8W18E11_18580 ENOG4108RTD type II secretion system protein K WP8W18E11_18630 ENOG4105F8V Hydrolase, tatD family WP8W18E11_18650 ENOG4107QRG dna polymerase iii WP8W18E11_18670 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) WP8W18E11_18680 ENOG4105BZ1 (ABC) transporter WP8W18E11_18710 ENOG4105FA0 parb-like partition protein WP8W18E11_18720 ENOG4107QJE Chromosome Partitioning Protein WP8W18E11_18740 ENOG4108S0S Nucleotidyl transferase WP8W18E11_18750 ENOG4105EHM Aminoglycoside phosphotransferase WP8W18E11_18760 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) WP8W18E11_18770 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) WP8W18E11_18780 ENOG4105D2N Aldolase WP8W18E11_18820 ENOG4108UHJ MAF-like protein WP8W18E11_18830 ENOG4105EZE Cupin 4 family protein WP8W18E11_18850 ENOG41080HT Transcriptional regulator, arsr family WP8W18E11_18870 ENOG4105XPP Protein of unknown function (DUF1275) WP8W18E11_18880 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme WP8W18E11_18890 ENOG4105BZ1 (ABC) transporter WP8W18E11_18910 ENOG4108ZX5 transcriptional regulator WP8W18E11_18930 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) WP8W18E11_18940 ENOG4105CK7 Sodium proline symporter WP8W18E11_18950 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_18960 ENOG4105C26 Dehydrogenase WP8W18E11_18970 ENOG4105YGK Pfam:UPF0157 WP8W18E11_19000 ENOG4108T58 Mg2 transport protein CorA WP8W18E11_19020 ENOG4108YYC ycei family WP8W18E11_19040 ENOG4105CV1 Transketolase (EC 2.2.1.1) WP8W18E11_19090 ENOG4108HWY Beta-lactamase WP8W18E11_19130 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) WP8W18E11_19140 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) WP8W18E11_19180 ENOG4105X0I Fimbrial WP8W18E11_19190 ENOG4105GQR Chaperone WP8W18E11_19240 ENOG4108IPJ Membrane WP8W18E11_19260 ENOG4105ETS cytosine purines uracil thiamine allantoin WP8W18E11_19280 ENOG4105CC0 LysR family Transcriptional regulator WP8W18E11_19320 ENOG41067SE Tetr family transcriptional regulator WP8W18E11_19350 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_19370 ENOG4105CDA abc transporter atp-binding protein WP8W18E11_19380 ENOG4105DRP amino acid AbC transporter WP8W18E11_19390 ENOG4105EAD ABC transporter WP8W18E11_19420 ENOG4107T8P acyl-Coa dehydrogenase WP8W18E11_19450 ENOG4105D01 (LipO)protein WP8W18E11_19460 ENOG4105D01 (LipO)protein WP8W18E11_19470 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_19480 ENOG4108UMI ABC transporter, permease WP8W18E11_19490 ENOG4105C3G gtp-binding protein WP8W18E11_19540 ENOG4108UMN azlc family WP8W18E11_19550 ENOG4105ZED uncharacterized protein ygaH WP8W18E11_19610 ENOG4105E7U AraC family transcriptional regulator WP8W18E11_19620 ENOG4108V06 Glutathione peroxidase WP8W18E11_19640 ENOG4105CHM Aminotransferase WP8W18E11_19650 ENOG4105CK2 sodium dicarboxylate symporter WP8W18E11_19670 ENOG4105C0B DNA polymerase III (alpha subunit) WP8W18E11_19720 ENOG4108JU3 Alkyl hydroperoxide reductase WP8W18E11_19750 ENOG4108KB2 LysR family Transcriptional regulator WP8W18E11_19760 ENOG4105D6J arsenicaL-resistance protein WP8W18E11_19770 ENOG41082YX Transcriptional regulator, arsr family WP8W18E11_19800 ENOG4105CPN adenine deaminase WP8W18E11_19820 ENOG4105CBN LysR family transcriptional regulator WP8W18E11_19840 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease WP8W18E11_19870 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component WP8W18E11_19880 ENOG4108IY8 ABC, transporter WP8W18E11_19890 ENOG4106FTQ Taurine ABC transporter, periplasmic WP8W18E11_19910 ENOG4105C54 Major Facilitator superfamily WP8W18E11_19950 ENOG4105C4M (Ubiquinol oxidase) subunit I WP8W18E11_19960 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii WP8W18E11_19970 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family WP8W18E11_19980 ENOG4108K70 Transcriptional regulator WP8W18E11_20010 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase WP8W18E11_20020 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase WP8W18E11_20050 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) WP8W18E11_20060 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase WP8W18E11_20080 ENOG4105ETT transcriptional Regulator, LysR family WP8W18E11_20100 ENOG4105DXI Major Facilitator superfamily WP8W18E11_20130 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family WP8W18E11_20140 ENOG41067MG lrgb family WP8W18E11_20150 ENOG4105VAW lrga family WP8W18E11_20160 ENOG4105CMU LysR family (Transcriptional regulator WP8W18E11_20170 ENOG4108SHQ Glutathione S-transferase WP8W18E11_20180 ENOG4105CYM Glutathione S-transferase WP8W18E11_20190 ENOG4105CBN LysR family transcriptional regulator WP8W18E11_20200 ENOG4105CHR reductase WP8W18E11_20220 ENOG4105D7W serine acetyltransferase WP8W18E11_20230 ENOG4105ESN nucleotide-binding protein WP8W18E11_20240 ENOG4105C9B Cysteine desulfurase WP8W18E11_20260 ENOG4105EXG Transcriptional regulator WP8W18E11_20270 ENOG4105CT1 (ABC) transporter WP8W18E11_20280 ENOG4107RP9 extracellular solute-binding protein, family 3 WP8W18E11_20300 ENOG4108HW4 amino acid AbC transporter WP8W18E11_20310 ENOG4105EAD ABC transporter WP8W18E11_20330 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase WP8W18E11_20340 ENOG4105BZU Histidine kinase WP8W18E11_20360 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_20420 ENOG4105CYX Short-chain dehydrogenase reductase Sdr WP8W18E11_20530 ENOG4105HEI LysR family (Transcriptional regulator WP8W18E11_20570 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_20580 ENOG4105R8C Transcriptional regulator WP8W18E11_20590 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_20600 ENOG4107QX3 carboxylase WP8W18E11_20610 ENOG4105E39 Enoyl-CoA hydratase WP8W18E11_20640 ENOG4105CC0 LysR family Transcriptional regulator WP8W18E11_20670 ENOG4105CSU acyl-Coa dehydrogenase WP8W18E11_20710 ENOG4107QNJ CoA-transferase subunit B WP8W18E11_20720 ENOG4107QP7 CoA-transferase subunit A WP8W18E11_20730 ENOG4107RGD Major Facilitator superfamily WP8W18E11_20740 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_20750 ENOG4105E39 Enoyl-CoA hydratase WP8W18E11_20760 ENOG4108R85 Short chain dehydrogenase WP8W18E11_20770 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase WP8W18E11_20780 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_20800 ENOG4105EQ0 Major Facilitator superfamily WP8W18E11_20810 ENOG4105EA8 2-Nitropropane dioxygenase WP8W18E11_20820 ENOG4108UKI Enoyl-CoA hydratase WP8W18E11_20850 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_20860 ENOG4107RGD Major Facilitator superfamily WP8W18E11_20870 ENOG4108KAZ Involved in phosphonate degradation (By similarity) WP8W18E11_20880 ENOG4107STF Involved in phosphonate degradation (By similarity) WP8W18E11_20900 ENOG4107RCV ABC transporter, permease WP8W18E11_20910 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_20920 ENOG4105C4Y ABC transporter WP8W18E11_20940 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase WP8W18E11_20950 ENOG4107HP6 Transcriptional regulator WP8W18E11_20970 ENOG4105HEI LysR family (Transcriptional regulator WP8W18E11_20980 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase WP8W18E11_20990 ENOG4105C26 Dehydrogenase WP8W18E11_21010 ENOG4105ETS cytosine purines uracil thiamine allantoin WP8W18E11_21020 ENOG4105C26 Dehydrogenase WP8W18E11_21030 ENOG4108M8W Monooxygenase WP8W18E11_21040 ENOG4105MXW flavin reductase domain protein, FMN-binding WP8W18E11_21050 ENOG4108MXF Alpha Beta Hydrolase WP8W18E11_21090 ENOG4105CPW cytochrome b561 WP8W18E11_21100 ENOG4107VGR Catalase WP8W18E11_21110 ENOG4105CSP Major Facilitator Superfamily WP8W18E11_21120 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase WP8W18E11_21130 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F WP8W18E11_21160 ENOG4105CF7 AraC family transcriptional regulator WP8W18E11_21230 ENOG4107YAU phenylacetic acid degradation protein WP8W18E11_21240 ENOG4108Z0R Transferase WP8W18E11_21250 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein WP8W18E11_21260 ENOG4105DZS Phenylacetate-CoA ligase WP8W18E11_21270 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_21280 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase WP8W18E11_21290 ENOG4108UKI Enoyl-CoA hydratase WP8W18E11_21300 ENOG4105E39 Enoyl-CoA hydratase WP8W18E11_21310 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) WP8W18E11_21320 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit WP8W18E11_21330 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit WP8W18E11_21340 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit WP8W18E11_21350 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit WP8W18E11_21360 ENOG4105DXM phenylacetic acid degradation protein WP8W18E11_21370 ENOG4105EJQ L-serine dehydratase WP8W18E11_21380 ENOG4107QTZ amino acid WP8W18E11_21390 ENOG4105CZJ Aldehyde dehydrogenase WP8W18E11_21440 ENOG4105MWK D-amino acid dehydrogenase, small subunit WP8W18E11_21480 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) WP8W18E11_21510 ENOG4108Z4X TRANSCRIPTIONal WP8W18E11_21530 ENOG4105WPN DNA integration recombination invertion protein WP8W18E11_21560 ENOG4105DJ2 Major Facilitator Superfamily WP8W18E11_21570 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase WP8W18E11_21580 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase WP8W18E11_21610 ENOG4105E2A Dehydrogenase WP8W18E11_21630 ENOG4105R8C Transcriptional regulator WP8W18E11_21650 ENOG4107R4J Chloride channel WP8W18E11_21660 ENOG4108JIK carboxylase WP8W18E11_21700 ENOG4105C5A transporter WP8W18E11_21710 ENOG4108WAV Transcriptional regulator WP8W18E11_21740 ENOG4105PAD Hydrolase WP8W18E11_21770 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) WP8W18E11_21830 ENOG4107TXC Transcriptional regulator WP8W18E11_21880 ENOG4106FTQ Taurine ABC transporter, periplasmic WP8W18E11_21890 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component WP8W18E11_21930 ENOG4105D2S major facilitator superfamily WP8W18E11_21950 ENOG4105D1S lipid A biosynthesis WP8W18E11_21960 ENOG4105BZU Histidine kinase WP8W18E11_21970 ENOG4107AQZ Membrane WP8W18E11_22010 ENOG4108Z4U Ferredoxin WP8W18E11_22090 ENOG4105DFG type I secretion outer membrane protein WP8W18E11_22100 ENOG4108IUZ ABC transporter WP8W18E11_22110 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA WP8W18E11_22140 ENOG4105C2X Arabinose 5-phosphate isomerase WP8W18E11_22270 ENOG4105II7 pyrroline-5-carboxylate reductase WP8W18E11_22290 ENOG4105VEQ Cold shock protein WP8W18E11_22300 ENOG410829K Lysine exporter protein (Lyse ygga) WP8W18E11_22360 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) WP8W18E11_22470 ENOG4108KB2 LysR family Transcriptional regulator WP8W18E11_22480 ENOG4105FUY alpha subunit WP8W18E11_22490 ENOG4108UKV benzoate 1,2-dioxygenase WP8W18E11_22500 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein WP8W18E11_22510 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase WP8W18E11_22520 ENOG4105DKK Benzoate WP8W18E11_22530 ENOG4105D2S major facilitator superfamily WP8W18E11_22560 ENOG4105CQ7 ATP-dependent helicase WP8W18E11_22570 ENOG4105D3R alkyl hydroperoxide reductase WP8W18E11_22590 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) WP8W18E11_22610 ENOG4108JU3 Alkyl hydroperoxide reductase WP8W18E11_22630 ENOG4108K3A Glutathione S-transferase WP8W18E11_22650 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) WP8W18E11_22660 ENOG4108TGY Glutathione S-transferase WP8W18E11_22680 ENOG4108ZG0 Ompa motb domain protein WP8W18E11_22690 ENOG4105CD3 dihydroorotase WP8W18E11_22750 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit WP8W18E11_22780 ENOG4108UKZ OsmC family WP8W18E11_22790 ENOG4107RYR Transcriptional regulator, Crp Fnr family WP8W18E11_22800 ENOG4105CPC Aldo Keto reductase WP8W18E11_22830 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis WP8W18E11_22850 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase WP8W18E11_22870 ENOG4105CFH Aspartokinase WP8W18E11_22890 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) WP8W18E11_22910 ENOG4105CPW cytochrome b561 WP8W18E11_22920 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) WP8W18E11_22930 ENOG4105C7N Xanthine uracil vitamin C permease WP8W18E11_22960 ENOG4105C26 Dehydrogenase WP8W18E11_23000 ENOG4105CUB amino acid WP8W18E11_23020 ENOG4105C85 amino acid WP8W18E11_23040 ENOG4107Y60 (LipO)protein WP8W18E11_23060 ENOG4106B0W Curli production assembly transport component CsgG WP8W18E11_23140 ENOG4105D01 (LipO)protein WP8W18E11_23170 ENOG4105DZR Type I site-specific deoxyribonuclease WP8W18E11_23180 ENOG4105CB5 ATP-dependent DNA helicase recG WP8W18E11_23190 ENOG4105ESI atpase involved in dna repair WP8W18E11_23340 ENOG4108UZX fmn reductase WP8W18E11_23380 ENOG4108W2Y isochorismatase WP8W18E11_23480 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase WP8W18E11_23520 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) WP8W18E11_23550 ENOG4108JQ5 ABC transporter WP8W18E11_23560 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component WP8W18E11_23570 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component WP8W18E11_23590 ENOG4105E9H Lytic Murein transglycosylase WP8W18E11_23590 ENOG4105E9H Lytic Murein transglycosylase WP8W18E11_23600 ENOG4107RZZ dna polymerase iii epsilon subunit WP8W18E11_23620 ENOG4105E09 nadh pyrophosphatase WP8W18E11_23640 ENOG4105W4M Transport-associated protein WP8W18E11_23660 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) WP8W18E11_23680 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) WP8W18E11_23690 ENOG4108ZUB Lysine exporter protein (Lyse ygga) WP8W18E11_23730 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family WP8W18E11_23740 ENOG4105D0A hydroxylase WP8W18E11_23750 ENOG4107RAQ aminopeptidase WP8W18E11_23820 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase WP8W18E11_23880 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b WP8W18E11_23900 ENOG4105D82 Glutamate dehydrogenase WP8W18E11_23910 ENOG4108R3D Electron transport complex WP8W18E11_23920 ENOG4105CSM endonuclease III WP8W18E11_23960 ENOG4105CJN penicillin-binding protein WP8W18E11_23970 ENOG4106H78 methyltransferase WP8W18E11_24000 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) WP8W18E11_24020 ENOG4105CQM Urea amidohydrolase subunit alpha WP8W18E11_24090 ENOG4107RET Isocitrate lyase WP8W18E11_24110 ENOG4105C37 (CBS) domain WP8W18E11_24120 ENOG4105D4T Citrate transporter WP8W18E11_24150 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) WP8W18E11_24180 ENOG4108MRJ WP8W18E11_24220 ENOG4105VCQ rubredoxin WP8W18E11_24230 ENOG4107QZF nitrite reductase NADPH large subunit WP8W18E11_24250 ENOG4105C5Q Transcriptional regulator WP8W18E11_24290 ENOG4107U91 Rhomboid family WP8W18E11_24300 ENOG4105CV6 ABC transporter, permease WP8W18E11_24310 ENOG4108I0Y (ABC) transporter WP8W18E11_24320 ENOG4108UJV acyl-CoA thioesterase i WP8W18E11_24360 ENOG4107RNH Outer membrane receptor FepA WP8W18E11_24390 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) WP8W18E11_24400 ENOG4105E6M Sulphatase-modifying factor protein WP8W18E11_24440 ENOG4105CJ3 phosphate transporter WP8W18E11_24450 ENOG4105C3R Methionine synthase WP8W18E11_24480 ENOG4105CSP Major Facilitator Superfamily WP8W18E11_24500 ENOG4108PZW LysR family Transcriptional regulator WP8W18E11_24520 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) WP8W18E11_24540 ENOG4105EU0 Major facilitator Superfamily WP8W18E11_24550 ENOG4108R6W Transcriptional regulator, ARAC family WP8W18E11_24560 ENOG4105CSV Glutaminase WP8W18E11_24570 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) WP8W18E11_24580 ENOG4105CSH Transporter WP8W18E11_24600 ENOG4105C7K acetolactate synthase WP8W18E11_24630 ENOG4105CHR reductase WP8W18E11_24640 ENOG4108MXF Alpha Beta Hydrolase WP8W18E11_24660 ENOG4105DJB Major Facilitator Superfamily WP8W18E11_24670 ENOG4108DNI pyridine nucleotide-disulfide oxidoreductase WP8W18E11_24690 ENOG4105CHR reductase WP8W18E11_24730 ENOG41069M3 Transcriptional regulator WP8W18E11_24760 ENOG4106YT9 Enoyl-CoA hydratase WP8W18E11_24780 ENOG4105CND Glycosyl transferase, family 2 WP8W18E11_24790 ENOG4107BJW polysaccharide deacetylase WP8W18E11_24810 ENOG4108VWS Yaeq family WP8W18E11_24830 ENOG4105CKI cobalamin synthesis protein WP8W18E11_24850 ENOG4108S4H thioesterase Superfamily protein WP8W18E11_24870 ENOG4105C94 Transporter WP8W18E11_24880 ENOG4105C94 Transporter WP8W18E11_24890 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) WP8W18E11_24940 ENOG4107QK5 Homocysteine s-methyltransferase WP8W18E11_24950 ENOG4105D5Q Arginine ornithine antiporter WP8W18E11_25010 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) WP8W18E11_25020 ENOG4105C54 Major Facilitator superfamily WP8W18E11_25090 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) WP8W18E11_25330 ENOG4105EFC phage portal protein HK97 family WP8W18E11_25340 ENOG4105CAR Terminase, large subunit WP8W18E11_25540 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) WP8W18E11_25550 ENOG4107R3N Filamentation induced by cAMP protein fic WP8W18E11_25560 ENOG4105F04 LysR family Transcriptional regulator WP8W18E11_25570 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_25590 ENOG4108M9J MaoC like domain protein WP8W18E11_25600 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F WP8W18E11_25630 ENOG4107QNJ CoA-transferase subunit B WP8W18E11_25660 ENOG4105NN7 muconolactone delta-isomerase WP8W18E11_25670 ENOG4105CYC Transferase WP8W18E11_25680 ENOG4105CHU acetyl-coa acetyltransferase WP8W18E11_25700 ENOG4105J5J Outer membrane porin WP8W18E11_25840 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) WP8W18E11_25980 ENOG4105DFP Integrase WP8W18E11_25990 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) WP8W18E11_26000 ENOG4105C0R drug resistance transporter emrb qaca subfamily WP8W18E11_26010 ENOG4105CW7 secretion protein, HlyD family WP8W18E11_26020 ENOG4108VUY thioesterase Superfamily protein WP8W18E11_26030 ENOG4105D52 delta-aminolevulinic acid dehydratase WP8W18E11_26040 ENOG4105MWK D-amino acid dehydrogenase, small subunit WP8W18E11_26050 ENOG4105ECP epimerase WP8W18E11_26090 ENOG4107RH8 nuclease SbcCD subunit D WP8W18E11_26100 ENOG4105EYH Exonuclease WP8W18E11_26110 ENOG4105DFA alanine racemase domain protein WP8W18E11_26120 ENOG4105CZX twitching motility protein WP8W18E11_26130 ENOG4105CZX twitching motility protein WP8W18E11_26140 ENOG41090R7 Ferric uptake WP8W18E11_26160 ENOG4105VDB UPF0125 protein WP8W18E11_26190 ENOG4105E7A Glutamine amidotransferase WP8W18E11_26220 ENOG4107QKV phosphomannomutase WP8W18E11_26240 ENOG4105C4R Atp-dependent dna helicase WP8W18E11_26250 ENOG4108ZG0 Ompa motb domain protein WP8W18E11_26260 ENOG4106HNH Acyl-transferase WP8W18E11_26290 ENOG4107QMS site-determining protein WP8W18E11_26320 ENOG4105CCF Lysine exporter protein (Lyse ygga) WP8W18E11_26330 ENOG4105CNU cell division protein FtsK WP8W18E11_26340 ENOG4105C3M thioredoxin reductase WP8W18E11_26350 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) WP8W18E11_26370 ENOG4105KEG ribosomal-protein-alanine acetyltransferase WP8W18E11_26460 ENOG4108YXA Membrane WP8W18E11_26470 ENOG4105EUB pirin domain protein WP8W18E11_26490 ENOG4105C4K Nad synthetase WP8W18E11_26510 ENOG4105E3J oxidoreductase WP8W18E11_26520 ENOG4105C26 Dehydrogenase WP8W18E11_26530 ENOG4105DVW rieske (2Fe-2S) WP8W18E11_26550 ENOG4105C94 Transporter WP8W18E11_26560 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) WP8W18E11_26570 ENOG4105EJC lysr family transcriptional regulator WP8W18E11_26590 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding WP8W18E11_26630 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase WP8W18E11_26640 ENOG4105C34 Pseudouridine synthase WP8W18E11_26650 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane WP8W18E11_26660 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) WP8W18E11_26690 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) WP8W18E11_26710 ENOG4105C5T Phosphoribosyl pyrophosphate synthase WP8W18E11_26770 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) WP8W18E11_26790 ENOG4105DWF phosphomethylpyrimidine kinase WP8W18E11_26800 ENOG4109066 lysm domain bon superfamily protein WP8W18E11_26820 ENOG4105CHR reductase WP8W18E11_26830 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase WP8W18E11_26850 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein WP8W18E11_26860 ENOG4108BPE -transporting atpase WP8W18E11_26870 ENOG4107RTD sua5 ycio yrdc ywlc family protein WP8W18E11_26880 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) WP8W18E11_26890 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) WP8W18E11_26900 ENOG4105FE9 pseudouridine synthase WP8W18E11_26920 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) WP8W18E11_26930 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) WP8W18E11_26950 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) WP8W18E11_26960 ENOG4108K4C ec 3.1.3.12 WP8W18E11_26970 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase WP8W18E11_26980 ENOG4106UW1 Major Facilitator superfamily WP8W18E11_27020 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) WP8W18E11_27040 ENOG4105HF0 Membrane WP8W18E11_27070 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY WP8W18E11_27090 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) WP8W18E11_27210 ENOG4105D1F ATP-binding protein WP8W18E11_27230 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) WP8W18E11_27290 ENOG4105K6H D-cysteine desulfhydrase WP8W18E11_27300 ENOG4105CBX hi0933 family WP8W18E11_27350 ENOG4105DP0 ferredoxin-NADP reductase WP8W18E11_27360 ENOG4105DUM transcriptional regulator, lysR family WP8W18E11_27410 ENOG4105C8S subunit m WP8W18E11_27420 ENOG4105D65 subunit l WP8W18E11_27440 ENOG4107UFS subunit j WP8W18E11_27470 ENOG4108IEH NADH dehydrogenase subunit g WP8W18E11_27480 ENOG4107QIZ NADH dehydrogenase WP8W18E11_27490 ENOG4105GKE subunit e WP8W18E11_27530 ENOG4105BZU Histidine kinase WP8W18E11_27550 ENOG4105E0F Histidine kinase WP8W18E11_27560 ENOG4107EXC regulatoR WP8W18E11_27570 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) WP8W18E11_27590 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) WP8W18E11_27680 ENOG4105DZR Type I site-specific deoxyribonuclease WP8W18E11_27800 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) WP8W18E11_27830 ENOG4105ETT transcriptional Regulator, LysR family WP8W18E11_27870 ENOG4105CH2 amidohydrolase WP8W18E11_27890 ENOG4106P55 Transcriptional regulator WP8W18E11_27920 ENOG4106P55 Transcriptional regulator WP8W18E11_27930 ENOG4107EFR Flavocytochrome c WP8W18E11_27950 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F WP8W18E11_27960 ENOG4107RGD Major Facilitator superfamily WP8W18E11_27970 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_27980 ENOG4105ETT transcriptional Regulator, LysR family WP8W18E11_28010 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) WP8W18E11_28020 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) WP8W18E11_28030 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) WP8W18E11_28070 ENOG4105E3B Multicopper oxidase WP8W18E11_28090 ENOG4108HCJ Hydrolase WP8W18E11_28100 ENOG4105DJV ribulose-phosphate 3-epimerase WP8W18E11_28150 ENOG41072GX Peptidase M22 Glycoprotease WP8W18E11_28160 ENOG4108Z0R Transferase WP8W18E11_28260 ENOG4105CRQ synthase (Component I) WP8W18E11_28280 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) WP8W18E11_28290 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) WP8W18E11_28300 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) WP8W18E11_28390 ENOG4105K56 Transcriptional regulator WP8W18E11_28400 ENOG4108ZHJ Organic hydroperoxide resistance protein WP8W18E11_28410 ENOG4107QHF type ii secretion system protein e WP8W18E11_28450 ENOG4105C2M dna polymerase I WP8W18E11_28460 ENOG4108VIA integral membrane protein WP8W18E11_28470 ENOG4105II7 pyrroline-5-carboxylate reductase WP8W18E11_28480 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) WP8W18E11_28500 ENOG4105C9X ppx gppa phosphatase WP8W18E11_28520 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) WP8W18E11_28550 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) WP8W18E11_28640 ENOG4105W39 Membrane WP8W18E11_28650 ENOG4105CYM Glutathione S-transferase WP8W18E11_28680 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_28690 ENOG4105N42 UPF0307 protein WP8W18E11_28700 ENOG41080Z8 PHOSPHOCARRIER protein WP8W18E11_28740 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase WP8W18E11_28750 ENOG4105DJ0 Poly(A) Polymerase WP8W18E11_28760 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein WP8W18E11_28770 ENOG4105DXN mazG family WP8W18E11_28790 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) WP8W18E11_28820 ENOG4105C6T cysteine synthase WP8W18E11_28830 ENOG4105BZU Histidine kinase WP8W18E11_28840 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase WP8W18E11_28850 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase WP8W18E11_28860 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) WP8W18E11_28890 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) WP8W18E11_28900 ENOG4105W8H transhydrogenase (subunit alpha WP8W18E11_28910 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) WP8W18E11_28920 ENOG4106UX7 integral membrane protein WP8W18E11_28950 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) WP8W18E11_28970 ENOG4107RSM transcriptional regulator WP8W18E11_28980 ENOG4105CUZ uba thif-type nad fad binding protein WP8W18E11_28990 ENOG4107QM5 aconitate hydratase WP8W18E11_29000 ENOG4105F8V Hydrolase, tatD family WP8W18E11_29030 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) WP8W18E11_29110 ENOG4105BZU Histidine kinase WP8W18E11_29140 ENOG4108ZP8 Acetolactate synthase small subunit WP8W18E11_29150 ENOG4105C7K acetolactate synthase WP8W18E11_29200 ENOG4105DJY efflux transporter, rnd family, mfp subunit WP8W18E11_29210 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) WP8W18E11_29220 ENOG4105ENJ RND efflux system, outer membrane lipoprotein WP8W18E11_29230 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH WP8W18E11_29250 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) WP8W18E11_29260 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) WP8W18E11_29280 ENOG4105VW4 glutaredoxin 3 WP8W18E11_29320 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) WP8W18E11_29330 ENOG4105C2D reductase WP8W18E11_29350 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) WP8W18E11_29410 ENOG4105C84 Histidine ammonia-lyase WP8W18E11_29430 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) WP8W18E11_29440 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_29470 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) WP8W18E11_29510 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) WP8W18E11_29550 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) WP8W18E11_29590 ENOG4105WVQ Fe-S assembly protein IscX WP8W18E11_29620 ENOG4105CN1 protease WP8W18E11_29650 ENOG4106HB6 Alpha beta hydrolase WP8W18E11_29670 ENOG4105C26 Dehydrogenase WP8W18E11_29680 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family WP8W18E11_29690 ENOG4105C6Z Gluconate WP8W18E11_29700 ENOG4108UHU Aldolase WP8W18E11_29710 ENOG4105C01 Dihydroxy-acid dehydratase WP8W18E11_29720 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) WP8W18E11_29730 ENOG4108DNC Involved in acetate metabolism (By similarity) WP8W18E11_29740 ENOG4107GFK fumarate WP8W18E11_29780 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) WP8W18E11_29800 ENOG4108ESX Receptor WP8W18E11_29820 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) WP8W18E11_29840 ENOG4105DWV Homoserine O-trans-acetylase WP8W18E11_30040 ENOG4105CIY formyltetrahydrofolate deformylase WP8W18E11_30060 ENOG4107RGH Aldehyde dehydrogenase WP8W18E11_30090 ENOG4105CKD glutathione-regulated potassium-efflux system protein WP8W18E11_30130 ENOG4105VFU Rna-binding protein WP8W18E11_30140 ENOG4105C4R Atp-dependent dna helicase WP8W18E11_30170 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) WP8W18E11_30190 ENOG4105KVH Transcriptional regulator WP8W18E11_30220 ENOG4105C5H ABC transporter WP8W18E11_30230 ENOG4105N14 lysine exporter protein LysE YggA WP8W18E11_30240 ENOG4105D1S lipid A biosynthesis WP8W18E11_30260 ENOG4105CK2 sodium dicarboxylate symporter WP8W18E11_30370 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) WP8W18E11_30420 ENOG4105DUM transcriptional regulator, lysR family WP8W18E11_30450 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase WP8W18E11_30480 ENOG4108W5M transcriptional regulator WP8W18E11_30510 ENOG4105D29 Helix-turn-helix type 11 domain protein WP8W18E11_30520 ENOG4107XGZ Hydrolase WP8W18E11_30530 ENOG4105EI2 Pseudouridine synthase WP8W18E11_30540 ENOG4105C03 ribonuclease WP8W18E11_30550 ENOG4105J5T Amp-dependent synthetase and ligase WP8W18E11_30560 ENOG4105CBN LysR family transcriptional regulator WP8W18E11_30580 ENOG4105CSA Coproporphyrinogen iii oxidase WP8W18E11_30600 ENOG4107QI1 Mate efflux family protein WP8W18E11_30620 ENOG4107T8P acyl-Coa dehydrogenase WP8W18E11_30680 ENOG4105BZ8 glutamate synthase WP8W18E11_30700 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) WP8W18E11_30710 ENOG4105C5X domain protein WP8W18E11_30740 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) WP8W18E11_30760 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase WP8W18E11_30780 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) WP8W18E11_30790 ENOG4108JU5 Magnesium and cobalt efflux protein WP8W18E11_30800 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) WP8W18E11_30810 ENOG4108Z7R Chaperone CsaA WP8W18E11_30830 ENOG4108VAU general secretion pathway protein G WP8W18E11_30840 ENOG4105D7Q type ii secretion system WP8W18E11_30850 ENOG4105C25 Primosomal protein n' WP8W18E11_30860 ENOG4105CKD glutathione-regulated potassium-efflux system protein WP8W18E11_30890 ENOG4105DVC DnaJ domain protein WP8W18E11_30900 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) WP8W18E11_30910 ENOG4107QUT magnesium and cobalt transport protein CorA WP8W18E11_30950 ENOG4107QYX exodeoxyribonuclease v alpha WP8W18E11_30960 ENOG4107QKA exodeoxyribonuclease V beta WP8W18E11_30970 ENOG4105DSY exodeoxyribonuclease V, gamma WP8W18E11_30990 ENOG4105CSR polyphosphate kinase 2 WP8W18E11_31010 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) WP8W18E11_31040 ENOG41061H0 Monooxygenase WP8W18E11_31050 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase WP8W18E11_31080 ENOG4105D65 subunit l WP8W18E11_31090 ENOG4108ZE9 Monovalent cation H antiporter subunit C WP8W18E11_31100 ENOG4107R4Z monovalent cation h antiporter subunit d WP8W18E11_31110 ENOG4105SC1 monovalent cation H antiporter subunit E WP8W18E11_31120 ENOG4105W4C monovalent cation H antiporter subunit F WP8W18E11_31130 ENOG4105KJM monovalent cation h antiporter subunit g WP8W18E11_31160 ENOG4105CHV Transcription elongation factor NusA WP8W18E11_31180 ENOG4107EJC Preprotein translocase subunit SecG WP8W18E11_31200 ENOG4107QHF type ii secretion system protein e WP8W18E11_31230 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) WP8W18E11_31250 ENOG4105C2N RNA methyltransferase TrmH family group 3 WP8W18E11_31280 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) WP8W18E11_31300 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) WP8W18E11_31360 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) WP8W18E11_31370 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase WP8W18E11_31500 ENOG4107ZXU DSBA oxidoreductase WP8W18E11_31530 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) WP8W18E11_31560 ENOG4105D3Y Na H antiporter WP8W18E11_31570 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) WP8W18E11_31670 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) WP8W18E11_31680 ENOG4105PM1 preprotein translocase subunit SecE WP8W18E11_31710 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) WP8W18E11_31720 ENOG4105TV9 FHA Domain-Containing protein WP8W18E11_31730 ENOG4105GVR general secretion pathway protein D WP8W18E11_31760 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS WP8W18E11_31810 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) WP8W18E11_31820 ENOG4108NEV two component transcriptional regulator, LytTR family WP8W18E11_31830 ENOG4108HRK Histidine kinase WP8W18E11_31860 ENOG4108UTW Plays a role in the regulation of phosphate uptake WP8W18E11_31870 ENOG4105DFG type I secretion outer membrane protein WP8W18E11_31880 ENOG4108RNG Permease of the drug metabolite transporter WP8W18E11_31930 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) WP8W18E11_31950 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) WP8W18E11_31960 ENOG4105CNI cell division protein FtsW WP8W18E11_31990 ENOG4105CE1 Ferrous iron transport protein b WP8W18E11_32010 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) WP8W18E11_32020 ENOG4105T95 Thiol disulfide interChange protein WP8W18E11_32030 ENOG4105D6E homoserine dehydrogenase WP8W18E11_32050 ENOG41061WM D-Alanyl-D-Alanine WP8W18E11_32070 ENOG4107TUY Histidine kinase WP8W18E11_32080 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family WP8W18E11_32090 ENOG4105CN1 protease WP8W18E11_32100 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) WP8W18E11_32110 ENOG4108K5H permease YjgP YjgQ family protein WP8W18E11_32190 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) WP8W18E11_32210 ENOG4105BZU Histidine kinase WP8W18E11_32240 ENOG4105C0P Mg chelatase subunit ChlI WP8W18E11_32250 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family WP8W18E11_32270 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) WP8W18E11_32290 ENOG4105EPF Outer membrane porin WP8W18E11_32300 ENOG4105F0N pyrophosphate phospho-hydrolase WP8W18E11_32330 ENOG4105CEY Amp-dependent synthetase and ligase WP8W18E11_32340 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) WP8W18E11_32350 ENOG41079KZ Major Facilitator Superfamily WP8W18E11_32360 ENOG4105EN6 Membrane WP8W18E11_32370 ENOG4105K5B UPF0225 protein WP8W18E11_32380 ENOG4105EE5 Membrane protein terC WP8W18E11_32390 ENOG4108URH decarboxylase WP8W18E11_32400 ENOG4105C0R drug resistance transporter emrb qaca subfamily WP8W18E11_32420 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) WP8W18E11_32430 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) WP8W18E11_32460 ENOG4105CCT upf0313 protein WP8W18E11_32500 ENOG4105CS1 NAD(P)H quinone oxidoreductase WP8W18E11_32520 ENOG4105C6T cysteine synthase WP8W18E11_32540 ENOG4105Y7M Transcriptional regulator, TetR family WP8W18E11_32620 ENOG4108IND Tetr family transcriptional regulator WP8W18E11_32630 ENOG4107RTG Major Facilitator superfamily WP8W18E11_32650 ENOG4108V06 Glutathione peroxidase WP8W18E11_32670 ENOG41090VV Protein of unknown function (DUF2846) WP8W18E11_32790 ENOG4105FDK ABC transporter WP8W18E11_32800 ENOG4105FAV ABC, transporter WP8W18E11_32810 ENOG410829K Lysine exporter protein (Lyse ygga) WP8W18E11_32820 ENOG4105EZR dyp-type peroxidase family protein WP8W18E11_32830 ENOG4107R1I NAD-dependent malic enzyme WP8W18E11_32880 ENOG4105EUB pirin domain protein WP8W18E11_32920 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) WP8W18E11_32930 ENOG4106MP8 UPF0754 membrane protein WP8W18E11_32940 ENOG4108VBZ doxx family WP8W18E11_32950 ENOG4105DQR SNARE associated Golgi WP8W18E11_32980 ENOG4107QJE Chromosome Partitioning Protein WP8W18E11_33000 ENOG4107PSF BolA-like protein WP8W18E11_33060 ENOG4107SQU synthase WP8W18E11_33070 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_33120 ENOG4105CSH Transporter WP8W18E11_33130 ENOG4105E39 Enoyl-CoA hydratase WP8W18E11_33140 ENOG4105E39 Enoyl-CoA hydratase WP8W18E11_33150 ENOG4105C1G acyl-Coa dehydrogenase WP8W18E11_33170 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase WP8W18E11_33180 ENOG4105C26 Dehydrogenase WP8W18E11_33200 ENOG4105C85 amino acid WP8W18E11_33210 ENOG4105C85 amino acid WP8W18E11_33220 ENOG4105M4H endoribonuclease L-psp WP8W18E11_33250 ENOG4105EW9 transcriptional regulator AsnC family WP8W18E11_33300 ENOG4105D3G Pseudouridine synthase WP8W18E11_33380 ENOG4108I0Z Aconitate hydratase WP8W18E11_33390 ENOG4105BZN citrate synthase WP8W18E11_33400 ENOG4105CR4 methylisocitrate lyase WP8W18E11_33410 ENOG4105DRR Transcriptional regulator, GntR family WP8W18E11_33420 ENOG4105CGF Aromatic amino acid aminotransferase WP8W18E11_33430 ENOG4105CXG d-lactate dehydrogenase WP8W18E11_33450 ENOG41073TP transcriptional regulator WP8W18E11_33460 ENOG4105DAA L-lactate WP8W18E11_33470 ENOG4107QKV phosphomannomutase WP8W18E11_33490 ENOG4105CMR udp-glucose 4-epimerase WP8W18E11_33510 ENOG4105C6Y Udp-glucose 6-dehydrogenase WP8W18E11_33520 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase WP8W18E11_33530 ENOG4105D3Q Sugar transferase WP8W18E11_33540 ENOG4108RYC glycosyltransferase WP8W18E11_33550 ENOG4105CG5 Glycosyl transferase (Group 1 WP8W18E11_33580 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase WP8W18E11_33590 ENOG4108UW5 maltose o-acetyltransferase WP8W18E11_33610 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase WP8W18E11_33620 ENOG4105J5G Transferase hexapeptide repeat containing protein WP8W18E11_33630 ENOG4107R5Z Oxidoreductase domain protein WP8W18E11_33640 ENOG4107QQG Dehydrogenase WP8W18E11_33650 ENOG4105DAY polysaccharide export protein WP8W18E11_33670 ENOG4105D75 Capsular exopolysaccharide family WP8W18E11_33680 ENOG4108V1T peptidylprolyl cis-trans isomerase WP8W18E11_33690 ENOG4108V1T peptidylprolyl cis-trans isomerase WP8W18E11_33700 ENOG4105CJR Integral membrane protein (MviN WP8W18E11_33710 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase WP8W18E11_33720 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase WP8W18E11_33740 ENOG4105HSS phospholipase C WP8W18E11_33790 ENOG41062JF Transcriptional regulator WP8W18E11_33800 ENOG4108Z33 Thiol disulfide Interchange Protein WP8W18E11_33820 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) WP8W18E11_33830 ENOG4105UBK short-chain dehydrogenase reductase WP8W18E11_33860 ENOG4107QZM n-acetylglutamate synthase WP8W18E11_33870 ENOG4105GVF (ABC) transporter WP8W18E11_33880 ENOG4105GVF (ABC) transporter WP8W18E11_33890 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) WP8W18E11_33900 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component WP8W18E11_33910 ENOG4108VM9 ABC, transporter WP8W18E11_33920 ENOG4108R86 Transcriptional regulator WP8W18E11_33930 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) WP8W18E11_33950 ENOG4105DTN riboflavin biosynthesis protein ribF WP8W18E11_33960 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) WP8W18E11_33980 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase WP8W18E11_34010 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) WP8W18E11_34120 ENOG4105CVE Lytic murein transglycosylase WP8W18E11_34140 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit WP8W18E11_34150 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) WP8W18E11_34170 ENOG4105DFU Cell wall formation (By similarity) WP8W18E11_34190 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase WP8W18E11_34200 ENOG4105DU1 integral membrane protein, terc WP8W18E11_34220 ENOG4106032 Glutathionylspermidine synthase WP8W18E11_34240 ENOG4107QUY Guanine deaminase WP8W18E11_34260 ENOG4108UGV hypoxanthine phosphoribosyltransferase WP8W18E11_34280 ENOG4105T95 Thiol disulfide interChange protein WP8W18E11_34290 ENOG4105PGM cation diffusion facilitator family transporter WP8W18E11_34320 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins WP8W18E11_P10070 ENOG4108JA2 transcriptioN-repair coupling factor WP8W18E11_P10110 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) WP8W18E11_P10460 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) WP8W18E11_P10580 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) WP8W18E11_P10650 ENOG4106J5W DNA polymerase III (alpha subunit) WP8W18E11_P10670 ENOG4105C0B DNA polymerase III (alpha subunit) WP8W18E11_P10800 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) WP8W18E11_P10810 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) WP8W18E11_P10880 ENOG4108BUD transposase WP8W18E11_P10900 ENOG4105DIJ Phosphoethanolamine transferase WP8W18E11_P10930 ENOG4107RZZ dna polymerase iii epsilon subunit WP8W18E11_P11070 ENOG4105D5G Transposase WP8W18E11_P11110 ENOG4105CVR type I restriction-modification system WP8W18E11_P11120 ENOG4107SCJ type I restriction enzyme EcoKI subunit R WP8W18E11_P20010 ENOG4105CH6 catalase WP8W18E11_P20120 ENOG4105C4W S-formylglutathione hydrolase