locus-tag	class	description
WP8W18E11_00020	COG0592	DNA-directed DNA polymerase activity
WP8W18E11_00040	COG0187	DNA topoisomerase II activity
WP8W18E11_00060	COG0586	Pfam SNARE associated Golgi protein
WP8W18E11_00070	COG0488	(ABC) transporter
WP8W18E11_00120	COG0596	Alpha beta hydrolase
WP8W18E11_00130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WP8W18E11_00140	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP8W18E11_00170	COG0733	neurotransmitter:sodium symporter activity
WP8W18E11_00240	COG0583	DNA-binding transcription factor activity
WP8W18E11_00250	COG2233	PERMEase
WP8W18E11_00280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_00350	COG2814	Major facilitator Superfamily
WP8W18E11_00360	COG0656	L-ascorbic acid biosynthetic process
WP8W18E11_00370	COG0583	DNA-binding transcription factor activity
WP8W18E11_00390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_00400	COG1064	alcohol dehydrogenase
WP8W18E11_00410	COG2818	Glycosylase
WP8W18E11_00440	COG1194	a g-specific adenine glycosylase
WP8W18E11_00480	COG2983	Belongs to the UPF0260 family
WP8W18E11_00490	COG2133	pyrroloquinoline quinone binding
WP8W18E11_00500	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WP8W18E11_00510	COG2116	formate transmembrane transporter activity
WP8W18E11_00550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP8W18E11_00560	COG1335	isochorismatase
WP8W18E11_00570	COG0385	Bile acid
WP8W18E11_00580	COG0534	Mate efflux family protein
WP8W18E11_00590	COG1683	Conserved Protein
WP8W18E11_00630	COG0625	glutathione transferase activity
WP8W18E11_00650	COG1113	amino acid transport
WP8W18E11_00670	COG0523	cobalamin synthesis protein
WP8W18E11_00690	COG2188	Transcriptional regulator
WP8W18E11_00750	COG0010	Belongs to the arginase family
WP8W18E11_00770	COG0546	phosphoglycolate phosphatase activity
WP8W18E11_00780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WP8W18E11_00790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WP8W18E11_00810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WP8W18E11_00820	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WP8W18E11_00910	COG0753	catalase activity
WP8W18E11_01010	COG0534	Mate efflux family protein
WP8W18E11_01020	COG0436	Aminotransferase
WP8W18E11_01030	COG2733	membrane
WP8W18E11_01060	COG2918	glutathione biosynthetic process
WP8W18E11_01080	COG3501	Rhs element vgr protein
WP8W18E11_01090	COG3179	chitinase
WP8W18E11_01130	COG3150	esterase
WP8W18E11_01150	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
WP8W18E11_01170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP8W18E11_01190	COG2233	PERMEase
WP8W18E11_01200	COG2351	hydroxyisourate hydrolase activity
WP8W18E11_01270	COG3706	GGDEF domain
WP8W18E11_01300	COG1393	Belongs to the ArsC family
WP8W18E11_01310	COG0708	Exodeoxyribonuclease III
WP8W18E11_01360	COG0189	ligase activity
WP8W18E11_01400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
WP8W18E11_01420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WP8W18E11_01450	COG4942	peptidase
WP8W18E11_01470	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP8W18E11_01490	COG2119	membrane
WP8W18E11_01500	COG4774	siderophore transport
WP8W18E11_01510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_01510	COG0426	domain, Protein
WP8W18E11_01560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WP8W18E11_01620	COG1902	pentaerythritol trinitrate reductase activity
WP8W18E11_01630	COG1519	Transferase
WP8W18E11_01640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP8W18E11_01650	COG0668	transmembrane transport
WP8W18E11_01670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP8W18E11_01680	COG1335	isochorismatase
WP8W18E11_01690	COG1522	sequence-specific DNA binding
WP8W18E11_01740	COG2205	protein histidine kinase activity
WP8W18E11_01740	COG2198	Histidine kinase
WP8W18E11_01740	COG0784	Response regulator, receiver
WP8W18E11_01750	COG3162	membrane
WP8W18E11_01760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP8W18E11_01780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WP8W18E11_01800	COG3706	GGDEF domain
WP8W18E11_01810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP8W18E11_01820	COG1309	transcriptional regulator
WP8W18E11_01860	COG0351	phosphomethylpyrimidine kinase
WP8W18E11_01860	COG0352	thiamine-phosphate diphosphorylase activity
WP8W18E11_01860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WP8W18E11_01880	COG2814	Major facilitator Superfamily
WP8W18E11_01920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WP8W18E11_01940	COG1113	amino acid transport
WP8W18E11_01960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WP8W18E11_01970	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_01990	COG1335	isochorismatase
WP8W18E11_02040	COG2814	Major facilitator Superfamily
WP8W18E11_02050	COG0583	DNA-binding transcription factor activity
WP8W18E11_02090	COG0667	Aldo Keto reductase
WP8W18E11_02160	COG1733	regulation of RNA biosynthetic process
WP8W18E11_02170	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP8W18E11_02180	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_02190	COG1881	PFAM PEBP family protein
WP8W18E11_02210	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WP8W18E11_02220	COG2207	Transcriptional regulator
WP8W18E11_02320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WP8W18E11_02400	COG1132	(ABC) transporter
WP8W18E11_02440	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WP8W18E11_02480	COG0427	acetyl-CoA hydrolase
WP8W18E11_02500	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_02520	COG0659	secondary active sulfate transmembrane transporter activity
WP8W18E11_02530	COG4221	oxidoreductase activity
WP8W18E11_02540	COG2873	o-acetylhomoserine
WP8W18E11_02550	COG0488	(ABC) transporter
WP8W18E11_02660	COG0833	amino acid
WP8W18E11_02730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WP8W18E11_02740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WP8W18E11_02770	COG2226	methyltransferase
WP8W18E11_02870	COG0070	glutamate synthase
WP8W18E11_02870	COG0067	glutamate synthase
WP8W18E11_02870	COG0069	glutamate synthase activity
WP8W18E11_02880	COG0493	'glutamate synthase
WP8W18E11_02900	COG1704	LemA family
WP8W18E11_02910	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WP8W18E11_02950	COG3307	-O-antigen
WP8W18E11_02990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP8W18E11_03010	COG0194	GDP metabolic process
WP8W18E11_03110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WP8W18E11_03150	COG5380	lipid catabolic process
WP8W18E11_03160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WP8W18E11_03210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP8W18E11_03220	COG0277	FAD linked oxidase domain protein
WP8W18E11_03240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
WP8W18E11_03250	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP8W18E11_03280	COG1289	transmembrane transporter activity
WP8W18E11_03300	COG0628	permease
WP8W18E11_03370	COG0833	amino acid
WP8W18E11_03380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WP8W18E11_03390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP8W18E11_03410	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_03490	COG0583	DNA-binding transcription factor activity
WP8W18E11_03540	COG0752	glycyl-tRNA synthetase alpha subunit
WP8W18E11_03590	COG0517	IMP dehydrogenase activity
WP8W18E11_03600	COG1983	PspC domain protein
WP8W18E11_03620	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_03650	COG0408	coproporphyrinogen oxidase activity
WP8W18E11_03690	COG0513	Belongs to the DEAD box helicase family
WP8W18E11_03710	COG1127	ABC transporter
WP8W18E11_03720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WP8W18E11_03740	COG2854	intermembrane phospholipid transfer
WP8W18E11_03760	COG0598	Magnesium transport protein CorA
WP8W18E11_03790	COG1040	competence protein
WP8W18E11_03800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WP8W18E11_03840	COG1946	Acyl-CoA thioesterase
WP8W18E11_03850	COG1301	dicarboxylic acid transport
WP8W18E11_03880	COG1959	2 iron, 2 sulfur cluster binding
WP8W18E11_03890	COG1017	nitric oxide dioxygenase activity
WP8W18E11_03890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP8W18E11_03900	COG0433	COG0433 Predicted ATPase
WP8W18E11_03910	COG0626	cystathionine gamma-synthase activity
WP8W18E11_04220	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_04230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WP8W18E11_04300	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WP8W18E11_04310	COG0339	signal peptide processing
WP8W18E11_04320	COG0557	exoribonuclease II activity
WP8W18E11_04370	COG0179	Fumarylacetoacetate (FAA) hydrolase
WP8W18E11_04380	COG2169	Transcriptional regulator
WP8W18E11_04390	COG0697	spore germination
WP8W18E11_04400	COG1295	ribonuclease BN
WP8W18E11_04470	COG1702	phosphate starvation-inducible protein PhoH
WP8W18E11_04490	COG1196	nuclear chromosome segregation
WP8W18E11_04490	COG0741	lytic transglycosylase activity
WP8W18E11_04490	COG0739	heme binding
WP8W18E11_04550	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WP8W18E11_04560	COG1183	phosphatidylcholine synthase activity
WP8W18E11_04600	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_04610	COG1309	transcriptional regulator
WP8W18E11_04640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP8W18E11_04650	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_04690	COG2969	positive regulation of protein catabolic process
WP8W18E11_04710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WP8W18E11_04730	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WP8W18E11_04740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP8W18E11_04750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP8W18E11_04790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WP8W18E11_04810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP8W18E11_04820	COG1408	metallophosphoesterase
WP8W18E11_04840	COG2199	diguanylate cyclase activity
WP8W18E11_04910	COG1607	acyl-coa hydrolase
WP8W18E11_04970	COG2350	Protein conserved in bacteria
WP8W18E11_04990	COG0613	PHP domain protein
WP8W18E11_05000	COG3781	membrane
WP8W18E11_05020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WP8W18E11_05030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP8W18E11_05050	COG1862	Preprotein translocase
WP8W18E11_05100	COG0582	viral genome integration into host DNA
WP8W18E11_05160	COG2205	protein histidine kinase activity
WP8W18E11_05170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WP8W18E11_05200	COG0726	polysaccharide deacetylase
WP8W18E11_05210	COG0438	transferase activity, transferring glycosyl groups
WP8W18E11_05240	COG1091	dTDP-4-dehydrorhamnose reductase activity
WP8W18E11_05270	COG1215	transferase activity, transferring glycosyl groups
WP8W18E11_05370	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_05380	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_05400	COG2205	protein histidine kinase activity
WP8W18E11_05410	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_05420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WP8W18E11_05460	COG2096	Adenosyltransferase
WP8W18E11_05470	COG4206	TonB-dependent receptor
WP8W18E11_05560	COG0285	dihydrofolate synthase activity
WP8W18E11_05600	COG0450	alkyl hydroperoxide reductase
WP8W18E11_05630	COG0477	Major facilitator Superfamily
WP8W18E11_05640	COG1272	protein, Hemolysin III
WP8W18E11_05700	COG0183	Belongs to the thiolase family
WP8W18E11_05710	COG2207	Transcriptional regulator
WP8W18E11_05750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP8W18E11_05790	COG0183	Belongs to the thiolase family
WP8W18E11_05810	COG2885	chlorophyll binding
WP8W18E11_05810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WP8W18E11_05830	COG1690	Belongs to the RtcB family
WP8W18E11_05840	COG0833	amino acid
WP8W18E11_05860	COG2233	PERMEase
WP8W18E11_05920	COG2094	Belongs to the DNA glycosylase MPG family
WP8W18E11_05930	COG4772	TonB-dependent receptor
WP8W18E11_05940	COG1902	pentaerythritol trinitrate reductase activity
WP8W18E11_05950	COG0679	Auxin Efflux Carrier
WP8W18E11_05970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP8W18E11_05980	COG0354	folic acid binding
WP8W18E11_06000	COG3189	MarR family transcriptional regulator
WP8W18E11_06010	COG2824	Alkylphosphonate utilization operon protein PhnA
WP8W18E11_06020	COG3422	double-strand break repair
WP8W18E11_06100	COG0840	transmembrane signaling receptor activity
WP8W18E11_06150	COG5510	response to toxic substance
WP8W18E11_06170	COG2832	Protein of unknown function (DUF454)
WP8W18E11_06180	COG1376	ErfK ybiS ycfS ynhG family protein
WP8W18E11_06200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP8W18E11_06220	COG1289	transmembrane transporter activity
WP8W18E11_06230	COG2814	Major facilitator Superfamily
WP8W18E11_06260	COG1115	amino acid carrier protein
WP8W18E11_06270	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP8W18E11_06280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP8W18E11_06290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
WP8W18E11_06300	COG3590	peptidase
WP8W18E11_06350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WP8W18E11_06370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
WP8W18E11_06380	COG1077	Cell shape determining protein MreB Mrl
WP8W18E11_06390	COG1792	Involved in formation and maintenance of cell shape
WP8W18E11_06400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WP8W18E11_06410	COG0424	maF-like protein
WP8W18E11_06420	COG1530	ribonuclease E activity
WP8W18E11_06440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP8W18E11_06460	COG0560	Phosphoserine phosphatase
WP8W18E11_06480	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP8W18E11_06530	COG2207	Transcriptional regulator
WP8W18E11_06560	COG1113	amino acid transport
WP8W18E11_06570	COG2828	Protein conserved in bacteria
WP8W18E11_06580	COG0142	geranyltranstransferase activity
WP8W18E11_06590	COG2315	Protein conserved in bacteria
WP8W18E11_06620	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP8W18E11_06660	COG2194	sulfuric ester hydrolase activity
WP8W18E11_06670	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_06680	COG0642	Histidine kinase
WP8W18E11_06700	COG0004	ammonium transporteR
WP8W18E11_06710	COG0583	DNA-binding transcription factor activity
WP8W18E11_06750	COG0525	valine-tRNA ligase activity
WP8W18E11_06770	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_06790	COG0393	Putative heavy-metal-binding
WP8W18E11_06800	COG0393	Putative heavy-metal-binding
WP8W18E11_06810	COG1538	Outer membrane efflux protein
WP8W18E11_06830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_06840	COG0671	phosphoesterase, PA-phosphatase related
WP8W18E11_06890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WP8W18E11_06920	COG1648	precorrin-2 dehydrogenase activity
WP8W18E11_06920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP8W18E11_06930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WP8W18E11_06940	COG1733	regulation of RNA biosynthetic process
WP8W18E11_06960	COG0531	amino acid
WP8W18E11_06990	COG0321	lipoyl(octanoyl) transferase activity
WP8W18E11_07000	COG2921	Belongs to the UPF0250 family
WP8W18E11_07080	COG2009	succinate dehydrogenase
WP8W18E11_07090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WP8W18E11_07100	COG1053	succinate dehydrogenase
WP8W18E11_07110	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WP8W18E11_07140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP8W18E11_07180	COG2354	Protein conserved in bacteria
WP8W18E11_07190	COG2321	neutral zinc metallopeptidase
WP8W18E11_07240	COG2843	Capsule synthesis protein
WP8W18E11_07270	COG0589	response to stress
WP8W18E11_07290	COG0251	oxidation-reduction process
WP8W18E11_07300	COG1309	transcriptional regulator
WP8W18E11_07330	COG0505	Belongs to the CarA family
WP8W18E11_07380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WP8W18E11_07390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WP8W18E11_07460	COG0477	Major facilitator Superfamily
WP8W18E11_07470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WP8W18E11_07500	COG1597	lipid kinase activity
WP8W18E11_07510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WP8W18E11_07550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP8W18E11_07560	COG0584	glycerophosphoryl diester phosphodiesterase
WP8W18E11_07600	COG0741	lytic transglycosylase activity
WP8W18E11_07640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP8W18E11_07660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP8W18E11_07680	COG3811	Belongs to the UPF0386 family
WP8W18E11_07820	COG0778	Nitroreductase
WP8W18E11_07850	COG1929	Belongs to the glycerate kinase type-1 family
WP8W18E11_07860	COG0243	molybdopterin cofactor binding
WP8W18E11_07870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP8W18E11_07880	COG3339	Conserved Protein
WP8W18E11_07900	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
WP8W18E11_07930	COG1113	amino acid transport
WP8W18E11_07950	COG0019	diaminopimelate decarboxylase activity
WP8W18E11_07970	COG1280	lysine exporter protein (LysE YggA)
WP8W18E11_07980	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WP8W18E11_08040	COG0463	Glycosyl transferase, family 2
WP8W18E11_08080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_08150	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP8W18E11_08160	COG1136	(ABC) transporter
WP8W18E11_08170	COG2333	competence protein COMEC
WP8W18E11_08170	COG0658	competence protein
WP8W18E11_08190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP8W18E11_08190	COG0616	signal peptide processing
WP8W18E11_08200	COG0596	Alpha beta hydrolase
WP8W18E11_08210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WP8W18E11_08230	COG0628	permease
WP8W18E11_08300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP8W18E11_08340	COG0823	Involved in the tonB-independent uptake of proteins
WP8W18E11_08380	COG0824	Thioesterase
WP8W18E11_08390	COG1473	amidohydrolase
WP8W18E11_08430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WP8W18E11_08430	COG0047	phosphoribosylformylglycinamidine synthase activity
WP8W18E11_08440	COG2814	Major facilitator Superfamily
WP8W18E11_08460	COG1024	Enoyl-CoA hydratase
WP8W18E11_08470	COG1051	belongs to the nudix hydrolase family
WP8W18E11_08470	COG1056	cytidyltransferase-related domain
WP8W18E11_08490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP8W18E11_08520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WP8W18E11_08550	COG4625	pathogenesis
WP8W18E11_08560	COG0583	DNA-binding transcription factor activity
WP8W18E11_08570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WP8W18E11_08580	COG4208	sulfate ABC transporter
WP8W18E11_08590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WP8W18E11_08610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WP8W18E11_08620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WP8W18E11_08630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WP8W18E11_08670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP8W18E11_08690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP8W18E11_08710	COG0681	Belongs to the peptidase S26 family
WP8W18E11_08740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WP8W18E11_08760	COG1381	Involved in DNA repair and RecF pathway recombination
WP8W18E11_08770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WP8W18E11_08790	COG4221	oxidoreductase activity
WP8W18E11_08830	COG0443	Heat shock 70 kDa protein
WP8W18E11_08850	COG0436	Aminotransferase
WP8W18E11_08890	COG0556	nucleotide-excision repair
WP8W18E11_09000	COG2070	2-Nitropropane dioxygenase
WP8W18E11_09060	COG1215	transferase activity, transferring glycosyl groups
WP8W18E11_09090	COG0415	Belongs to the DNA photolyase family
WP8W18E11_09110	COG1252	NADH dehydrogenase
WP8W18E11_09120	COG1686	Belongs to the peptidase S11 family
WP8W18E11_09150	COG1187	pseudouridine synthase activity
WP8W18E11_09200	COG0477	Major facilitator Superfamily
WP8W18E11_09210	COG0583	DNA-binding transcription factor activity
WP8W18E11_09240	COG0612	Peptidase, M16
WP8W18E11_09290	COG0352	thiamine-phosphate diphosphorylase activity
WP8W18E11_09360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP8W18E11_09380	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP8W18E11_09410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WP8W18E11_09420	COG0076	glutamate decarboxylase activity
WP8W18E11_09440	COG1522	sequence-specific DNA binding
WP8W18E11_09450	COG3961	Belongs to the TPP enzyme family
WP8W18E11_09460	COG1113	amino acid transport
WP8W18E11_09470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WP8W18E11_09480	COG0573	inorganic phosphate transmembrane transporter activity
WP8W18E11_09500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WP8W18E11_09510	COG0616	signal peptide processing
WP8W18E11_09580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WP8W18E11_09590	COG1686	Belongs to the peptidase S11 family
WP8W18E11_09640	COG0583	DNA-binding transcription factor activity
WP8W18E11_09650	COG1067	ATP-dependent peptidase activity
WP8W18E11_09700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
WP8W18E11_09740	COG1966	Carbon starvation protein
WP8W18E11_09750	COG2879	small protein
WP8W18E11_09820	COG1335	isochorismatase
WP8W18E11_09830	COG0583	DNA-binding transcription factor activity
WP8W18E11_09860	COG0596	Alpha beta hydrolase
WP8W18E11_09880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP8W18E11_09950	COG1741	Belongs to the pirin family
WP8W18E11_09970	COG2964	Protein conserved in bacteria
WP8W18E11_10000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP8W18E11_10030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP8W18E11_10040	COG4605	iron ion homeostasis
WP8W18E11_10050	COG4604	ABC transporter, ATP-binding protein
WP8W18E11_10060	COG4607	ABC-type enterochelin transport system periplasmic component
WP8W18E11_10070	COG4774	siderophore transport
WP8W18E11_10090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WP8W18E11_10100	COG1021	2,3-dihydroxybenzoate-AMP ligase
WP8W18E11_10110	COG1535	isochorismatase
WP8W18E11_10110	COG3433	isochorismatase activity
WP8W18E11_10140	COG1132	(ABC) transporter
WP8W18E11_10160	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
WP8W18E11_10210	COG3739	integral membrane protein
WP8W18E11_10270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP8W18E11_10330	COG0308	aminopeptidase N
WP8W18E11_10340	COG0512	Glutamine amidotransferase of anthranilate synthase
WP8W18E11_10360	COG3104	oligopeptide transport
WP8W18E11_10370	COG0174	glutamine synthetase
WP8W18E11_10390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WP8W18E11_10430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WP8W18E11_10440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WP8W18E11_10450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP8W18E11_10490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP8W18E11_10500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WP8W18E11_10510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WP8W18E11_10540	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_10550	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP8W18E11_10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP8W18E11_10590	COG2223	nitrite transmembrane transporter activity
WP8W18E11_10610	COG0024	Methionine aminopeptidase
WP8W18E11_10620	COG0052	Belongs to the universal ribosomal protein uS2 family
WP8W18E11_10650	COG2207	Transcriptional regulator
WP8W18E11_10710	COG2951	lytic endotransglycosylase activity
WP8W18E11_10720	COG0772	Belongs to the SEDS family
WP8W18E11_10750	COG0842	Transport permease protein
WP8W18E11_10760	COG1131	(ABC) transporter
WP8W18E11_10830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_10860	COG4215	(ABC) transporter
WP8W18E11_10870	COG4160	amino acid transport
WP8W18E11_10880	COG4598	ABC transporter
WP8W18E11_10900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP8W18E11_10920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_10930	COG0384	phenazine biosynthesis protein PhzF
WP8W18E11_10940	COG0384	phenazine biosynthesis protein PhzF
WP8W18E11_10960	COG1720	tRNA m6t6A37 methyltransferase activity
WP8W18E11_11000	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_11010	COG0642	Histidine kinase
WP8W18E11_11030	COG0494	nUDIX hydrolase
WP8W18E11_11050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP8W18E11_11060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WP8W18E11_11070	COG3139	Protein of unknown function (DUF1315)
WP8W18E11_11080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP8W18E11_11090	COG1301	dicarboxylic acid transport
WP8W18E11_11100	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_11110	COG2819	hydrolase of the alpha beta superfamily
WP8W18E11_11130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WP8W18E11_11150	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP8W18E11_11190	COG1690	Belongs to the RtcB family
WP8W18E11_11200	COG1234	tRNA 3'-trailer cleavage
WP8W18E11_11210	COG4650	regulator
WP8W18E11_11270	COG2363	Small membrane protein
WP8W18E11_11310	COG0513	Belongs to the DEAD box helicase family
WP8W18E11_11330	COG0778	Nitroreductase
WP8W18E11_11390	COG1286	toxin biosynthetic process
WP8W18E11_11440	COG4783	chaperone-mediated protein folding
WP8W18E11_11450	COG1610	YqeY-like protein
WP8W18E11_11510	COG2815	serine threonine protein kinase
WP8W18E11_11510	COG0515	serine threonine protein kinase
WP8W18E11_11610	COG3111	PFAM Bacterial OB fold (BOF) protein
WP8W18E11_11660	COG3243	poly(R)-hydroxyalkanoic acid synthase
WP8W18E11_11670	COG0786	glutamate:sodium symporter activity
WP8W18E11_11690	COG2186	Transcriptional regulator
WP8W18E11_11790	COG0477	Major facilitator Superfamily
WP8W18E11_11800	COG1051	belongs to the nudix hydrolase family
WP8W18E11_11860	COG2995	paraquat-inducible protein a
WP8W18E11_11870	COG3008	intermembrane lipid transfer
WP8W18E11_11870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP8W18E11_11900	COG1794	racemase activity, acting on amino acids and derivatives
WP8W18E11_11980	COG1301	dicarboxylic acid transport
WP8W18E11_12000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP8W18E11_12010	COG2011	ABC-type metal ion transport system permease component
WP8W18E11_12020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP8W18E11_12030	COG1464	Belongs to the NlpA lipoprotein family
WP8W18E11_12040	COG0151	Belongs to the GarS family
WP8W18E11_12050	COG0138	bifunctional purine biosynthesis protein purh
WP8W18E11_12060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WP8W18E11_12120	COG2308	Evidence 4 Homologs of previously reported genes of
WP8W18E11_12140	COG1305	Transglutaminase-like
WP8W18E11_12160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP8W18E11_12170	COG0305	Participates in initiation and elongation during chromosome replication
WP8W18E11_12220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WP8W18E11_12240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WP8W18E11_12250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WP8W18E11_12300	COG1649	PFAM Uncharacterised BCR, COG1649
WP8W18E11_12300	COG0726	polysaccharide deacetylase
WP8W18E11_12310	COG1215	transferase activity, transferring glycosyl groups
WP8W18E11_12320	COG1215	transferase activity, transferring glycosyl groups
WP8W18E11_12330	COG3658	cytochrome
WP8W18E11_12350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP8W18E11_12380	COG0583	DNA-binding transcription factor activity
WP8W18E11_12440	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_12450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP8W18E11_12460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_12490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WP8W18E11_12520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
WP8W18E11_12530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
WP8W18E11_12540	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
WP8W18E11_12550	COG2205	protein histidine kinase activity
WP8W18E11_12560	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_12570	COG0174	glutamine synthetase
WP8W18E11_12610	COG0729	surface antigen
WP8W18E11_12660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP8W18E11_12670	COG2814	Major facilitator Superfamily
WP8W18E11_12700	COG0583	DNA-binding transcription factor activity
WP8W18E11_12730	COG1187	pseudouridine synthase activity
WP8W18E11_12770	COG0802	atpase or kinase
WP8W18E11_12780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP8W18E11_12800	COG1923	regulation of RNA biosynthetic process
WP8W18E11_12810	COG0697	spore germination
WP8W18E11_12860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP8W18E11_12870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP8W18E11_12870	COG0519	Catalyzes the synthesis of GMP from XMP
WP8W18E11_12880	COG4302	ethanolamine ammonia-lyase activity
WP8W18E11_12890	COG4303	Ethanolamine ammonia lyase large subunit
WP8W18E11_12900	COG0531	amino acid
WP8W18E11_12940	COG1454	alcohol dehydrogenase
WP8W18E11_12950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP8W18E11_13000	COG0308	aminopeptidase N
WP8W18E11_13040	COG1605	Chorismate mutase
WP8W18E11_13090	COG1309	transcriptional regulator
WP8W18E11_13140	COG0668	transmembrane transport
WP8W18E11_13200	COG4773	Receptor
WP8W18E11_13240	COG0488	(ABC) transporter
WP8W18E11_13250	COG0589	response to stress
WP8W18E11_13300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WP8W18E11_13320	COG3135	benzoate transporter
WP8W18E11_13330	COG1522	sequence-specific DNA binding
WP8W18E11_13350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP8W18E11_13360	COG0583	DNA-binding transcription factor activity
WP8W18E11_13380	COG0183	Belongs to the thiolase family
WP8W18E11_13400	COG2030	dehydratase
WP8W18E11_13440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WP8W18E11_13470	COG0824	Thioesterase
WP8W18E11_13480	COG1454	alcohol dehydrogenase
WP8W18E11_13500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WP8W18E11_13540	COG0069	glutamate synthase activity
WP8W18E11_13560	COG1196	nuclear chromosome segregation
WP8W18E11_13610	COG2814	Major facilitator Superfamily
WP8W18E11_13640	COG0511	ligase activity, forming carbon-carbon bonds
WP8W18E11_13670	COG1116	anion transmembrane transporter activity
WP8W18E11_13670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WP8W18E11_13680	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_13700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP8W18E11_13700	COG2146	nitrite reductase [NAD(P)H] activity
WP8W18E11_13710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP8W18E11_13720	COG0243	molybdopterin cofactor binding
WP8W18E11_13740	COG0243	molybdopterin cofactor binding
WP8W18E11_13750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WP8W18E11_13780	COG0315	cyclic pyranopterin monophosphate synthase activity
WP8W18E11_13780	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP8W18E11_13790	COG0303	'Molybdopterin
WP8W18E11_13810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_13820	COG0697	spore germination
WP8W18E11_13860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP8W18E11_13870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP8W18E11_13980	COG2204	response regulator
WP8W18E11_13990	COG3852	Histidine kinase
WP8W18E11_14030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WP8W18E11_14040	COG0575	Belongs to the CDS family
WP8W18E11_14070	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP8W18E11_14110	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP8W18E11_14130	COG2137	regulation of response to DNA damage stimulus
WP8W18E11_14150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WP8W18E11_14160	COG1011	Hydrolase
WP8W18E11_14210	COG1522	sequence-specific DNA binding
WP8W18E11_14230	COG1113	amino acid transport
WP8W18E11_14260	COG0659	secondary active sulfate transmembrane transporter activity
WP8W18E11_14270	COG2135	peptidase activity
WP8W18E11_14300	COG5001	Diguanylate cyclase
WP8W18E11_14300	COG3300	MHYT domain
WP8W18E11_14340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP8W18E11_14340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP8W18E11_14340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WP8W18E11_14350	COG1105	Belongs to the carbohydrate kinase PfkB family
WP8W18E11_14360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP8W18E11_14360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP8W18E11_14420	COG0024	Methionine aminopeptidase
WP8W18E11_14430	COG0583	DNA-binding transcription factor activity
WP8W18E11_14450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WP8W18E11_14460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP8W18E11_14470	COG0516	GMP reductase activity
WP8W18E11_14470	COG0517	IMP dehydrogenase activity
WP8W18E11_14520	COG0552	protein localization to endoplasmic reticulum
WP8W18E11_14540	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
WP8W18E11_14570	COG4890	Cyd operon protein YbgT
WP8W18E11_14580	COG1294	oxidase, subunit
WP8W18E11_14610	COG1585	Membrane protein implicated in regulation of membrane protease activity
WP8W18E11_14630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP8W18E11_14640	COG4774	siderophore transport
WP8W18E11_14670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP8W18E11_14680	COG0569	domain protein
WP8W18E11_14690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP8W18E11_14750	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WP8W18E11_14760	COG0542	response to heat
WP8W18E11_14810	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP8W18E11_14810	COG1902	pentaerythritol trinitrate reductase activity
WP8W18E11_14900	COG2323	membrane
WP8W18E11_14910	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WP8W18E11_14930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WP8W18E11_14940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WP8W18E11_14950	COG0183	Belongs to the thiolase family
WP8W18E11_14960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WP8W18E11_14970	COG0596	Alpha beta hydrolase
WP8W18E11_14980	COG2271	Major facilitator Superfamily
WP8W18E11_14990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP8W18E11_15000	COG3485	protocatechuate 3,4-dioxygenase
WP8W18E11_15010	COG3485	protocatechuate 3,4-dioxygenase
WP8W18E11_15020	COG0710	3-dehydroquinate dehydratase activity
WP8W18E11_15030	COG3420	alginic acid biosynthetic process
WP8W18E11_15040	COG3659	wide pore channel activity
WP8W18E11_15050	COG4993	Dehydrogenase
WP8W18E11_15070	COG2391	methyltransferase activity
WP8W18E11_15100	COG1414	Transcriptional regulator
WP8W18E11_15110	COG0583	DNA-binding transcription factor activity
WP8W18E11_15120	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_15170	COG2814	Major facilitator Superfamily
WP8W18E11_15190	COG0154	amidase activity
WP8W18E11_15230	COG4638	Rieske (2fe-2S)
WP8W18E11_15250	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_15270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_15290	COG3733	amine oxidase
WP8W18E11_15310	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_15330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WP8W18E11_15340	COG0183	Belongs to the thiolase family
WP8W18E11_15350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WP8W18E11_15360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WP8W18E11_15380	COG4829	muconolactone delta-isomerase
WP8W18E11_15390	COG4948	Mandelate Racemase Muconate Lactonizing
WP8W18E11_15400	COG0583	DNA-binding transcription factor activity
WP8W18E11_15420	COG2186	Transcriptional regulator
WP8W18E11_15460	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_15490	COG1902	pentaerythritol trinitrate reductase activity
WP8W18E11_15490	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP8W18E11_15510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WP8W18E11_15530	COG0789	Transcriptional regulator
WP8W18E11_15580	COG1309	transcriptional regulator
WP8W18E11_15590	COG0583	DNA-binding transcription factor activity
WP8W18E11_15600	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_15610	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_15620	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_15640	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_15660	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_15820	COG2188	Transcriptional regulator
WP8W18E11_15850	COG0583	DNA-binding transcription factor activity
WP8W18E11_15880	COG1566	PFAM secretion protein HlyD family protein
WP8W18E11_15910	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_15920	COG0129	dihydroxy-acid dehydratase activity
WP8W18E11_15940	COG0583	DNA-binding transcription factor activity
WP8W18E11_15950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP8W18E11_15970	COG2084	Dehydrogenase
WP8W18E11_15980	COG2207	Transcriptional regulator
WP8W18E11_15990	COG1064	alcohol dehydrogenase
WP8W18E11_16020	COG1120	ATPase activity
WP8W18E11_16220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WP8W18E11_16290	COG2856	Zn peptidase
WP8W18E11_16390	COG2207	Transcriptional regulator
WP8W18E11_16420	COG2205	protein histidine kinase activity
WP8W18E11_16430	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_16440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_16450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP8W18E11_16510	COG3539	Fimbrial protein
WP8W18E11_16580	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
WP8W18E11_16600	COG0753	catalase activity
WP8W18E11_16630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP8W18E11_16750	COG1535	isochorismatase
WP8W18E11_16750	COG3433	isochorismatase activity
WP8W18E11_16760	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_16770	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WP8W18E11_16780	COG4149	molybdate abc transporter
WP8W18E11_16790	COG0725	ABC transporter, periplasmic molybdate-binding protein
WP8W18E11_16810	COG4638	Rieske (2fe-2S)
WP8W18E11_16820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WP8W18E11_16830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP8W18E11_16830	COG0543	2 iron, 2 sulfur cluster binding
WP8W18E11_16860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_16880	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_16910	COG2207	Transcriptional regulator
WP8W18E11_16920	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_16930	COG2610	gluconate transmembrane transporter activity
WP8W18E11_16950	COG1309	transcriptional regulator
WP8W18E11_17000	COG0583	DNA-binding transcription factor activity
WP8W18E11_17030	COG2031	fatty acid transporter
WP8W18E11_17040	COG0183	Belongs to the thiolase family
WP8W18E11_17050	COG0583	DNA-binding transcription factor activity
WP8W18E11_17060	COG0583	DNA-binding transcription factor activity
WP8W18E11_17090	COG1027	Aspartate ammonia-lyase
WP8W18E11_17110	COG0477	Major facilitator Superfamily
WP8W18E11_17150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP8W18E11_17160	COG4521	taurine ABC transporter
WP8W18E11_17190	COG2188	Transcriptional regulator
WP8W18E11_17210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WP8W18E11_17220	COG1733	regulation of RNA biosynthetic process
WP8W18E11_17230	COG2207	Transcriptional regulator
WP8W18E11_17230	COG3708	Transcriptional regulator
WP8W18E11_17260	COG0730	response to heat
WP8W18E11_17280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP8W18E11_17280	COG3453	Protein conserved in bacteria
WP8W18E11_17300	COG3781	membrane
WP8W18E11_17310	COG1063	alcohol dehydrogenase
WP8W18E11_17330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP8W18E11_17340	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP8W18E11_17350	COG0022	dehydrogenase e1 component
WP8W18E11_17360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WP8W18E11_17370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP8W18E11_17400	COG3706	GGDEF domain
WP8W18E11_17430	COG0133	tryptophan synthase activity
WP8W18E11_17450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WP8W18E11_17510	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WP8W18E11_17520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WP8W18E11_17570	COG2226	methyltransferase
WP8W18E11_17680	COG0842	Transport permease protein
WP8W18E11_17690	COG0842	Transport permease protein
WP8W18E11_17700	COG1131	(ABC) transporter
WP8W18E11_17730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP8W18E11_17740	COG4773	Receptor
WP8W18E11_17780	COG0730	response to heat
WP8W18E11_17790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP8W18E11_17820	COG0406	alpha-ribazole phosphatase activity
WP8W18E11_17830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
WP8W18E11_17860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP8W18E11_17920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP8W18E11_17940	COG4264	IucA IucC family
WP8W18E11_17950	COG4264	IucA IucC family
WP8W18E11_17960	COG2814	Major facilitator Superfamily
WP8W18E11_17990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WP8W18E11_18020	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_18030	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_18040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP8W18E11_18050	COG2207	Transcriptional regulator
WP8W18E11_18060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP8W18E11_18070	COG0776	regulation of translation
WP8W18E11_18120	COG0822	iron-sulfur transferase activity
WP8W18E11_18130	COG0316	Belongs to the HesB IscA family
WP8W18E11_18190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP8W18E11_18230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP8W18E11_18240	COG0702	epimerase
WP8W18E11_18310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP8W18E11_18330	COG0339	signal peptide processing
WP8W18E11_18430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WP8W18E11_18440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WP8W18E11_18500	COG0776	regulation of translation
WP8W18E11_18630	COG0084	hydrolase, TatD family'
WP8W18E11_18670	COG1663	tetraacyldisaccharide 4'-kinase activity
WP8W18E11_18680	COG1132	(ABC) transporter
WP8W18E11_18700	COG0811	peptide transport
WP8W18E11_18710	COG1475	DNA binding
WP8W18E11_18720	COG1192	Involved in chromosome partitioning
WP8W18E11_18740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP8W18E11_18770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP8W18E11_18780	COG0191	fructose-bisphosphate aldolase activity
WP8W18E11_18820	COG0424	maF-like protein
WP8W18E11_18830	COG2850	peptidyl-arginine hydroxylation
WP8W18E11_18850	COG0640	Transcriptional regulator
WP8W18E11_18870	COG3619	membrane
WP8W18E11_18880	COG3122	Protein conserved in bacteria
WP8W18E11_18890	COG1132	(ABC) transporter
WP8W18E11_18930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
WP8W18E11_18940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP8W18E11_18960	COG0506	proline dehydrogenase activity
WP8W18E11_18960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WP8W18E11_18960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WP8W18E11_18970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WP8W18E11_19000	COG3698	Phosphodiester glycosidase
WP8W18E11_19020	COG2353	YceI-like domain
WP8W18E11_19040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP8W18E11_19130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP8W18E11_19130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP8W18E11_19180	COG3539	Fimbrial protein
WP8W18E11_19190	COG3121	Chaperone
WP8W18E11_19240	COG0697	spore germination
WP8W18E11_19260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WP8W18E11_19280	COG0583	DNA-binding transcription factor activity
WP8W18E11_19320	COG1309	transcriptional regulator
WP8W18E11_19350	COG1522	sequence-specific DNA binding
WP8W18E11_19370	COG1126	abc transporter atp-binding protein
WP8W18E11_19380	COG0765	amino acid transport
WP8W18E11_19390	COG0765	amino acid transport
WP8W18E11_19450	COG1464	Belongs to the NlpA lipoprotein family
WP8W18E11_19470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP8W18E11_19480	COG2011	ABC-type metal ion transport system permease component
WP8W18E11_19490	COG0012	GTP binding
WP8W18E11_19540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
WP8W18E11_19620	COG0386	Belongs to the glutathione peroxidase family
WP8W18E11_19640	COG0436	Aminotransferase
WP8W18E11_19650	COG1301	dicarboxylic acid transport
WP8W18E11_19720	COG3634	alkyl hydroperoxide reductase activity
WP8W18E11_19750	COG0583	DNA-binding transcription factor activity
WP8W18E11_19760	COG0798	PFAM Bile acid sodium symporter
WP8W18E11_19770	COG0640	Transcriptional regulator
WP8W18E11_19800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WP8W18E11_19820	COG0583	DNA-binding transcription factor activity
WP8W18E11_19840	COG1953	Uracil, thiamine, allantoin
WP8W18E11_19860	COG2175	clavaminate synthase activity
WP8W18E11_19870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP8W18E11_19880	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WP8W18E11_19890	COG4521	taurine ABC transporter
WP8W18E11_19910	COG0477	Major facilitator Superfamily
WP8W18E11_19950	COG1271	oxidase subunit
WP8W18E11_19960	COG1294	oxidase, subunit
WP8W18E11_19970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_20010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WP8W18E11_20050	COG3052	prosthetic group binding
WP8W18E11_20060	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
WP8W18E11_20080	COG0583	DNA-binding transcription factor activity
WP8W18E11_20100	COG2814	Major facilitator Superfamily
WP8W18E11_20130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_20140	COG1346	cytolysis
WP8W18E11_20160	COG0583	DNA-binding transcription factor activity
WP8W18E11_20170	COG0625	glutathione transferase activity
WP8W18E11_20180	COG0625	glutathione transferase activity
WP8W18E11_20190	COG0583	DNA-binding transcription factor activity
WP8W18E11_20220	COG1045	serine acetyltransferase
WP8W18E11_20230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP8W18E11_20240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP8W18E11_20270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP8W18E11_20280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP8W18E11_20300	COG0765	amino acid transport
WP8W18E11_20310	COG0765	amino acid transport
WP8W18E11_20340	COG2205	protein histidine kinase activity
WP8W18E11_20340	COG0784	Response regulator, receiver
WP8W18E11_20420	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_20530	COG0583	DNA-binding transcription factor activity
WP8W18E11_20570	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_20580	COG1309	transcriptional regulator
WP8W18E11_20590	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_20600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP8W18E11_20610	COG1024	Enoyl-CoA hydratase
WP8W18E11_20620	COG4770	biotin carboxylase activity
WP8W18E11_20640	COG0583	DNA-binding transcription factor activity
WP8W18E11_20670	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_20690	COG2814	Major facilitator Superfamily
WP8W18E11_20710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WP8W18E11_20720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WP8W18E11_20730	COG2814	Major facilitator Superfamily
WP8W18E11_20740	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_20750	COG1024	Enoyl-CoA hydratase
WP8W18E11_20760	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_20770	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP8W18E11_20780	COG0183	Belongs to the thiolase family
WP8W18E11_20800	COG2814	Major facilitator Superfamily
WP8W18E11_20820	COG1024	Enoyl-CoA hydratase
WP8W18E11_20850	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_20860	COG2814	Major facilitator Superfamily
WP8W18E11_20870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP8W18E11_20880	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WP8W18E11_20910	COG3842	ATPase activity
WP8W18E11_20920	COG1840	ABC-type Fe3 transport system, periplasmic component
WP8W18E11_20940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP8W18E11_20950	COG1414	Transcriptional regulator
WP8W18E11_20970	COG0583	DNA-binding transcription factor activity
WP8W18E11_20980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP8W18E11_20990	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_21010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WP8W18E11_21020	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_21030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP8W18E11_21040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_21050	COG2267	carboxylic ester hydrolase activity
WP8W18E11_21090	COG3038	cytochrome b561
WP8W18E11_21100	COG0753	catalase activity
WP8W18E11_21110	COG2271	Major facilitator Superfamily
WP8W18E11_21120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP8W18E11_21130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WP8W18E11_21160	COG2207	Transcriptional regulator
WP8W18E11_21220	COG3209	COG3209 Rhs family protein
WP8W18E11_21230	COG2050	protein possibly involved in aromatic compounds catabolism
WP8W18E11_21250	COG3327	negative regulation of DNA-templated transcription, initiation
WP8W18E11_21260	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
WP8W18E11_21270	COG0183	Belongs to the thiolase family
WP8W18E11_21280	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP8W18E11_21290	COG1024	Enoyl-CoA hydratase
WP8W18E11_21300	COG1024	Enoyl-CoA hydratase
WP8W18E11_21310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP8W18E11_21320	COG2151	metal-sulfur cluster biosynthetic enzyme
WP8W18E11_21330	COG3396	Phenylacetate-CoA oxygenase
WP8W18E11_21340	COG3460	Phenylacetate-CoA oxygenase
WP8W18E11_21350	COG3396	Phenylacetate-CoA oxygenase
WP8W18E11_21360	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_21360	COG2030	dehydratase
WP8W18E11_21370	COG1760	l-serine dehydratase
WP8W18E11_21380	COG0531	amino acid
WP8W18E11_21390	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_21440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP8W18E11_21480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP8W18E11_21510	COG0789	Transcriptional regulator
WP8W18E11_21530	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
WP8W18E11_21560	COG2807	transmembrane transport
WP8W18E11_21570	COG0439	Biotin carboxylase
WP8W18E11_21580	COG0439	Biotin carboxylase
WP8W18E11_21610	COG1063	alcohol dehydrogenase
WP8W18E11_21630	COG1309	transcriptional regulator
WP8W18E11_21650	COG0038	chloride channel
WP8W18E11_21660	COG4770	biotin carboxylase activity
WP8W18E11_21700	COG1914	H( )-stimulated, divalent metal cation uptake system
WP8W18E11_21710	COG0583	DNA-binding transcription factor activity
WP8W18E11_21740	COG1011	Hydrolase
WP8W18E11_21770	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP8W18E11_21830	COG0789	Transcriptional regulator
WP8W18E11_21880	COG4521	taurine ABC transporter
WP8W18E11_21890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP8W18E11_21900	COG1116	anion transmembrane transporter activity
WP8W18E11_21910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WP8W18E11_21930	COG2814	Major facilitator Superfamily
WP8W18E11_21950	COG1560	Kdo2-lipid A biosynthetic process
WP8W18E11_21970	COG5006	permease, DMT superfamily
WP8W18E11_21980	COG1522	sequence-specific DNA binding
WP8W18E11_22010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WP8W18E11_22030	COG4122	O-methyltransferase activity
WP8W18E11_22090	COG1538	Outer membrane efflux protein
WP8W18E11_22100	COG1137	ATPase activity
WP8W18E11_22110	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WP8W18E11_22130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WP8W18E11_22220	COG2814	Major facilitator Superfamily
WP8W18E11_22290	COG1278	Cold shock
WP8W18E11_22300	COG1280	lysine exporter protein (LysE YggA)
WP8W18E11_22360	COG1570	exodeoxyribonuclease VII activity
WP8W18E11_22470	COG0583	DNA-binding transcription factor activity
WP8W18E11_22480	COG4638	Rieske (2fe-2S)
WP8W18E11_22490	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
WP8W18E11_22500	COG0633	Ferredoxin
WP8W18E11_22500	COG0543	2 iron, 2 sulfur cluster binding
WP8W18E11_22510	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_22520	COG3135	benzoate transporter
WP8W18E11_22530	COG2814	Major facilitator Superfamily
WP8W18E11_22560	COG1643	Atp-dependent helicase
WP8W18E11_22570	COG0450	alkyl hydroperoxide reductase
WP8W18E11_22590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WP8W18E11_22610	COG3634	alkyl hydroperoxide reductase activity
WP8W18E11_22650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WP8W18E11_22660	COG0625	glutathione transferase activity
WP8W18E11_22680	COG2885	chlorophyll binding
WP8W18E11_22750	COG0542	response to heat
WP8W18E11_22780	COG1765	OsmC-like protein
WP8W18E11_22800	COG0667	Aldo Keto reductase
WP8W18E11_22830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WP8W18E11_22850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP8W18E11_22870	COG0527	aspartate kinase activity
WP8W18E11_22890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WP8W18E11_22910	COG3038	cytochrome b561
WP8W18E11_22920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP8W18E11_22930	COG2252	PERMEase
WP8W18E11_22960	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_23000	COG0531	amino acid
WP8W18E11_23020	COG1113	amino acid transport
WP8W18E11_23170	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP8W18E11_23190	COG1196	nuclear chromosome segregation
WP8W18E11_23340	COG0431	NADPH-dependent FMN reductase
WP8W18E11_23370	COG2207	Transcriptional regulator
WP8W18E11_23380	COG1335	isochorismatase
WP8W18E11_23480	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP8W18E11_23480	COG1902	pentaerythritol trinitrate reductase activity
WP8W18E11_23500	COG5001	Diguanylate cyclase
WP8W18E11_23500	COG2203	Gaf domain
WP8W18E11_23500	COG3706	GGDEF domain
WP8W18E11_23500	COG4251	negative regulation of phosphorylation
WP8W18E11_23520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP8W18E11_23550	COG4172	Belongs to the ABC transporter superfamily
WP8W18E11_23560	COG4239	(ABC) transporter, permease
WP8W18E11_23570	COG4174	ABC transporter (Permease)
WP8W18E11_23590	COG1388	LysM domain
WP8W18E11_23590	COG0741	lytic transglycosylase activity
WP8W18E11_23590	COG1388	LysM domain
WP8W18E11_23590	COG0741	lytic transglycosylase activity
WP8W18E11_23600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP8W18E11_23680	COG0583	DNA-binding transcription factor activity
WP8W18E11_23690	COG1279	arginine transmembrane transporter activity
WP8W18E11_23730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP8W18E11_23740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP8W18E11_23750	COG0006	proline dipeptidase activity
WP8W18E11_23820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WP8W18E11_23880	COG3384	dioxygenase
WP8W18E11_23900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WP8W18E11_23910	COG2878	Part of a membrane complex involved in electron transport
WP8W18E11_23920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WP8W18E11_23960	COG0768	penicillin binding
WP8W18E11_23970	COG0742	ribosomal rna small subunit methyltransferase
WP8W18E11_24000	COG0830	nickel cation binding
WP8W18E11_24020	COG0804	urea catabolic process
WP8W18E11_24110	COG1253	flavin adenine dinucleotide binding
WP8W18E11_24120	COG2851	Citrate transporter
WP8W18E11_24220	COG1773	rubredoxin
WP8W18E11_24230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP8W18E11_24250	COG0583	DNA-binding transcription factor activity
WP8W18E11_24300	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WP8W18E11_24310	COG4181	ATPase activity
WP8W18E11_24400	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WP8W18E11_24440	COG0306	phosphate transporter
WP8W18E11_24460	COG3958	Transketolase
WP8W18E11_24470	COG3959	Transketolase, thiamine diphosphate binding domain
WP8W18E11_24480	COG2271	Major facilitator Superfamily
WP8W18E11_24490	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_24500	COG0583	DNA-binding transcription factor activity
WP8W18E11_24540	COG2223	nitrite transmembrane transporter activity
WP8W18E11_24550	COG2207	Transcriptional regulator
WP8W18E11_24560	COG2066	Belongs to the glutaminase family
WP8W18E11_24570	COG0242	peptide deformylase activity
WP8W18E11_24580	COG0477	Major facilitator Superfamily
WP8W18E11_24600	COG0028	Belongs to the TPP enzyme family
WP8W18E11_24630	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_24640	COG2267	carboxylic ester hydrolase activity
WP8W18E11_24660	COG2271	Major facilitator Superfamily
WP8W18E11_24670	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP8W18E11_24690	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_24730	COG1414	Transcriptional regulator
WP8W18E11_24760	COG1024	Enoyl-CoA hydratase
WP8W18E11_24780	COG1215	transferase activity, transferring glycosyl groups
WP8W18E11_24790	COG1649	PFAM Uncharacterised BCR, COG1649
WP8W18E11_24790	COG0726	polysaccharide deacetylase
WP8W18E11_24810	COG4681	YaeQ
WP8W18E11_24830	COG0523	cobalamin synthesis protein
WP8W18E11_24850	COG1607	acyl-coa hydrolase
WP8W18E11_24870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WP8W18E11_24880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WP8W18E11_24890	COG1309	transcriptional regulator
WP8W18E11_24940	COG2040	homocysteine
WP8W18E11_24950	COG0531	amino acid
WP8W18E11_25010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP8W18E11_25020	COG0477	Major facilitator Superfamily
WP8W18E11_25090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP8W18E11_25330	COG4695	Portal protein
WP8W18E11_25340	COG1802	Transcriptional regulator
WP8W18E11_25340	COG4626	Terminase
WP8W18E11_25540	COG0582	viral genome integration into host DNA
WP8W18E11_25550	COG3177	Filamentation induced by cAMP protein fic
WP8W18E11_25560	COG0583	DNA-binding transcription factor activity
WP8W18E11_25570	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_25590	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
WP8W18E11_25600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WP8W18E11_25610	COG0583	DNA-binding transcription factor activity
WP8W18E11_25630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WP8W18E11_25640	COG2814	Major facilitator Superfamily
WP8W18E11_25660	COG4829	muconolactone delta-isomerase
WP8W18E11_25670	COG0427	acetyl-CoA hydrolase
WP8W18E11_25680	COG0183	Belongs to the thiolase family
WP8W18E11_25740	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
WP8W18E11_25740	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
WP8W18E11_25840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP8W18E11_25980	COG0582	viral genome integration into host DNA
WP8W18E11_25990	COG0405	Gamma-glutamyltransferase
WP8W18E11_26000	COG2814	Major facilitator Superfamily
WP8W18E11_26020	COG2050	protein possibly involved in aromatic compounds catabolism
WP8W18E11_26050	COG1090	epimerase
WP8W18E11_26090	COG0420	3'-5' exonuclease activity
WP8W18E11_26140	COG0735	belongs to the Fur family
WP8W18E11_26150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP8W18E11_26190	COG0121	glutamine amidotransferase
WP8W18E11_26220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP8W18E11_26240	COG0210	DNA helicase
WP8W18E11_26250	COG2885	chlorophyll binding
WP8W18E11_26260	COG0204	Acyl-transferase
WP8W18E11_26290	COG2894	cell division
WP8W18E11_26320	COG1280	lysine exporter protein (LysE YggA)
WP8W18E11_26330	COG1674	ftsk spoiiie
WP8W18E11_26330	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP8W18E11_26340	COG0492	ferredoxin-NADP+ reductase activity
WP8W18E11_26350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WP8W18E11_26370	COG0456	acetyltransferase
WP8W18E11_26490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP8W18E11_26490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WP8W18E11_26520	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_26560	COG0473	3-isopropylmalate dehydrogenase activity
WP8W18E11_26570	COG0583	DNA-binding transcription factor activity
WP8W18E11_26590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP8W18E11_26640	COG0564	pseudouridine synthase activity
WP8W18E11_26660	COG0358	DNA primase activity
WP8W18E11_26690	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WP8W18E11_26710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WP8W18E11_26770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP8W18E11_26790	COG0351	phosphomethylpyrimidine kinase
WP8W18E11_26790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WP8W18E11_26790	COG0352	thiamine-phosphate diphosphorylase activity
WP8W18E11_26800	COG1652	LysM domain
WP8W18E11_26850	COG1399	metal-binding, possibly nucleic acid-binding protein
WP8W18E11_26860	COG3101	peptidyl-lysine hydroxylation
WP8W18E11_26870	COG0009	L-threonylcarbamoyladenylate synthase
WP8W18E11_26880	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
WP8W18E11_26890	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WP8W18E11_26920	COG4106	trans-aconitate 2-methyltransferase activity
WP8W18E11_26950	COG2226	methyltransferase
WP8W18E11_26950	COG0596	Alpha beta hydrolase
WP8W18E11_26950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WP8W18E11_26960	COG1877	trehalose-phosphatase activity
WP8W18E11_26970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
WP8W18E11_26980	COG2223	nitrite transmembrane transporter activity
WP8W18E11_27020	COG1196	nuclear chromosome segregation
WP8W18E11_27040	COG0730	response to heat
WP8W18E11_27070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP8W18E11_27090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP8W18E11_27210	COG0489	protein tyrosine kinase activity
WP8W18E11_27230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP8W18E11_27230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP8W18E11_27290	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WP8W18E11_27300	COG2081	HI0933 family
WP8W18E11_27320	COG0668	transmembrane transport
WP8W18E11_27360	COG0583	DNA-binding transcription factor activity
WP8W18E11_27410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP8W18E11_27420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WP8W18E11_27480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WP8W18E11_27550	COG2205	protein histidine kinase activity
WP8W18E11_27560	COG0745	RESPONSE REGULATOR receiver
WP8W18E11_27590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP8W18E11_27680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP8W18E11_27800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WP8W18E11_27830	COG0583	DNA-binding transcription factor activity
WP8W18E11_27870	COG1473	amidohydrolase
WP8W18E11_27890	COG0583	DNA-binding transcription factor activity
WP8W18E11_27920	COG0583	DNA-binding transcription factor activity
WP8W18E11_27930	COG1053	succinate dehydrogenase
WP8W18E11_27950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WP8W18E11_27960	COG2814	Major facilitator Superfamily
WP8W18E11_27970	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_27980	COG0583	DNA-binding transcription factor activity
WP8W18E11_27990	COG1063	alcohol dehydrogenase
WP8W18E11_28010	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WP8W18E11_28020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
WP8W18E11_28030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WP8W18E11_28070	COG2132	Multicopper oxidase
WP8W18E11_28090	COG0561	phosphatase activity
WP8W18E11_28100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WP8W18E11_28150	COG1214	PFAM Peptidase M22, glycoprotease
WP8W18E11_28260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WP8W18E11_28280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WP8W18E11_28290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WP8W18E11_28300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WP8W18E11_28370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP8W18E11_28390	COG1846	Transcriptional regulator
WP8W18E11_28400	COG1764	response to oxidative stress
WP8W18E11_28480	COG0037	tRNA processing
WP8W18E11_28500	COG0248	Ppx GppA phosphatase
WP8W18E11_28550	COG0072	phenylalanine-tRNA ligase activity
WP8W18E11_28640	COG1238	metal cluster binding
WP8W18E11_28650	COG0625	glutathione transferase activity
WP8W18E11_28680	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_28690	COG3028	Belongs to the UPF0307 family
WP8W18E11_28700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP8W18E11_28740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WP8W18E11_28750	COG0617	tRNA 3'-terminal CCA addition
WP8W18E11_28760	COG1555	photosystem II stabilization
WP8W18E11_28770	COG3956	TIGRFAM MazG family protein
WP8W18E11_28790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP8W18E11_28830	COG5002	protein histidine kinase activity
WP8W18E11_28830	COG2205	protein histidine kinase activity
WP8W18E11_28830	COG0784	Response regulator, receiver
WP8W18E11_28840	COG1024	Enoyl-CoA hydratase
WP8W18E11_28850	COG2084	Dehydrogenase
WP8W18E11_28860	COG3622	Belongs to the hyi family
WP8W18E11_28920	COG0697	spore germination
WP8W18E11_28940	COG2814	Major facilitator Superfamily
WP8W18E11_28950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP8W18E11_28970	COG0583	DNA-binding transcription factor activity
WP8W18E11_28980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WP8W18E11_29000	COG0084	hydrolase, TatD family'
WP8W18E11_29030	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WP8W18E11_29070	COG3501	Rhs element vgr protein
WP8W18E11_29140	COG0440	acetolactate synthase activity
WP8W18E11_29150	COG0028	Belongs to the TPP enzyme family
WP8W18E11_29200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP8W18E11_29210	COG0577	efflux transmembrane transporter activity
WP8W18E11_29210	COG1136	(ABC) transporter
WP8W18E11_29220	COG1538	Outer membrane efflux protein
WP8W18E11_29250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WP8W18E11_29260	COG1162	GTPase activity
WP8W18E11_29280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP8W18E11_29320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP8W18E11_29330	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_29410	COG2986	histidine ammonia-lyase
WP8W18E11_29430	COG1216	Glycosyl transferase, family 2
WP8W18E11_29440	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_29460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP8W18E11_29550	COG1426	Protein conserved in bacteria
WP8W18E11_29620	COG0793	Belongs to the peptidase S41A family
WP8W18E11_29650	COG2267	carboxylic ester hydrolase activity
WP8W18E11_29670	COG1012	belongs to the aldehyde dehydrogenase family
WP8W18E11_29680	COG3265	gluconokinase activity
WP8W18E11_29700	COG0800	Aldolase
WP8W18E11_29720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP8W18E11_29730	COG0280	phosphate acetyltransferase
WP8W18E11_29730	COG0857	belongs to the CobB CobQ family
WP8W18E11_29740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WP8W18E11_29740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WP8W18E11_29780	COG0740	serine-type endopeptidase activity
WP8W18E11_29800	COG4774	siderophore transport
WP8W18E11_29820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP8W18E11_29840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WP8W18E11_29840	COG2813	Specifically methylates the guanine in position
WP8W18E11_30040	COG0788	formyltetrahydrofolate deformylase activity
WP8W18E11_30090	COG4651	solute:proton antiporter activity
WP8W18E11_30090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP8W18E11_30130	COG0724	RNA recognition motif
WP8W18E11_30140	COG0210	DNA helicase
WP8W18E11_30190	COG1733	regulation of RNA biosynthetic process
WP8W18E11_30210	COG2900	Belongs to the SlyX family
WP8W18E11_30230	COG1280	lysine exporter protein (LysE YggA)
WP8W18E11_30240	COG1560	Kdo2-lipid A biosynthetic process
WP8W18E11_30260	COG1301	dicarboxylic acid transport
WP8W18E11_30370	COG0473	3-isopropylmalate dehydrogenase activity
WP8W18E11_30480	COG0583	DNA-binding transcription factor activity
WP8W18E11_30500	COG0625	glutathione transferase activity
WP8W18E11_30510	COG2378	regulation of single-species biofilm formation
WP8W18E11_30520	COG0546	phosphoglycolate phosphatase activity
WP8W18E11_30540	COG1530	ribonuclease E activity
WP8W18E11_30550	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_30560	COG0583	DNA-binding transcription factor activity
WP8W18E11_30570	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_30580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP8W18E11_30600	COG0534	Mate efflux family protein
WP8W18E11_30630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WP8W18E11_30700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WP8W18E11_30710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP8W18E11_30740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
WP8W18E11_30760	COG0644	oxidoreductase
WP8W18E11_30760	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
WP8W18E11_30780	COG0425	Belongs to the sulfur carrier protein TusA family
WP8W18E11_30790	COG4535	Mg2 and Co2 transporter CorC
WP8W18E11_30810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP8W18E11_30850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WP8W18E11_30860	COG0475	glutathione-regulated potassium exporter activity
WP8W18E11_30860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP8W18E11_30890	COG0484	heat shock protein binding
WP8W18E11_30900	COG0789	Transcriptional regulator
WP8W18E11_30910	COG0598	Magnesium transport protein CorA
WP8W18E11_30950	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP8W18E11_30960	COG1074	ATP-dependent DNA helicase activity
WP8W18E11_30970	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WP8W18E11_31010	COG2226	methyltransferase
WP8W18E11_31040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP8W18E11_31050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WP8W18E11_31080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WP8W18E11_31080	COG2111	Na H antiporter
WP8W18E11_31090	COG1006	Multisubunit Na H antiporter MnhC subunit
WP8W18E11_31100	COG0651	ATP synthesis coupled electron transport
WP8W18E11_31120	COG2212	antiporter activity
WP8W18E11_31160	COG0195	Participates in both transcription termination and antitermination
WP8W18E11_31230	COG0237	dephospho-CoA kinase activity
WP8W18E11_31250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP8W18E11_31280	COG0497	DNA recombination
WP8W18E11_31300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP8W18E11_31360	COG2169	Transcriptional regulator
WP8W18E11_31360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WP8W18E11_31370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WP8W18E11_31500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WP8W18E11_31530	COG0326	Molecular chaperone. Has ATPase activity
WP8W18E11_31560	COG2056	Na+-H+ antiporter family
WP8W18E11_31570	COG0596	Alpha beta hydrolase
WP8W18E11_31710	COG0546	phosphoglycolate phosphatase activity
WP8W18E11_31720	COG1716	ATPase activity
WP8W18E11_31810	COG0181	hydroxymethylbilane synthase activity
WP8W18E11_31830	COG3275	phosphorelay sensor kinase activity
WP8W18E11_31870	COG1538	Outer membrane efflux protein
WP8W18E11_31880	COG0697	spore germination
WP8W18E11_31930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WP8W18E11_31940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP8W18E11_31950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP8W18E11_31960	COG0772	Belongs to the SEDS family
WP8W18E11_32010	COG4974	Belongs to the 'phage' integrase family
WP8W18E11_32020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP8W18E11_32040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP8W18E11_32060	COG2197	response regulator
WP8W18E11_32090	COG0793	Belongs to the peptidase S41A family
WP8W18E11_32100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WP8W18E11_32110	COG0795	lipopolysaccharide-transporting ATPase activity
WP8W18E11_32190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP8W18E11_32190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP8W18E11_32210	COG0004	ammonium transporteR
WP8W18E11_32220	COG0347	Belongs to the P(II) protein family
WP8W18E11_32240	COG0606	chelatase, subunit chli
WP8W18E11_32250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP8W18E11_32270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP8W18E11_32300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WP8W18E11_32330	COG0318	PFAM AMP-dependent synthetase and ligase
WP8W18E11_32350	COG0477	Major facilitator Superfamily
WP8W18E11_32360	COG2860	membrane
WP8W18E11_32370	COG3012	SEC-C Motif Domain Protein
WP8W18E11_32380	COG1253	flavin adenine dinucleotide binding
WP8W18E11_32400	COG0477	Major facilitator Superfamily
WP8W18E11_32420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP8W18E11_32430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP8W18E11_32500	COG0655	NAD(P)H dehydrogenase (quinone) activity
WP8W18E11_32520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WP8W18E11_32540	COG1309	transcriptional regulator
WP8W18E11_32610	COG0697	spore germination
WP8W18E11_32620	COG1309	transcriptional regulator
WP8W18E11_32650	COG0386	Belongs to the glutathione peroxidase family
WP8W18E11_32790	COG1121	(ABC) transporter
WP8W18E11_32800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WP8W18E11_32810	COG1280	lysine exporter protein (LysE YggA)
WP8W18E11_32820	COG2837	iron assimilation
WP8W18E11_32830	COG0281	malic enzyme
WP8W18E11_32920	COG0519	Catalyzes the synthesis of GMP from XMP
WP8W18E11_32920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP8W18E11_32930	COG4399	Belongs to the UPF0754 family
WP8W18E11_32940	COG2259	Doxx family
WP8W18E11_32950	COG0586	Pfam SNARE associated Golgi protein
WP8W18E11_32980	COG1192	Involved in chromosome partitioning
WP8W18E11_33000	COG0271	Belongs to the BolA IbaG family
WP8W18E11_33060	COG0300	oxidoreductase activity
WP8W18E11_33060	COG3321	synthase
WP8W18E11_33060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP8W18E11_33060	COG4221	oxidoreductase activity
WP8W18E11_33070	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_33090	COG2197	response regulator
WP8W18E11_33110	COG3916	Acyl-homoserine-lactone synthase
WP8W18E11_33120	COG0477	Major facilitator Superfamily
WP8W18E11_33130	COG1024	Enoyl-CoA hydratase
WP8W18E11_33140	COG1024	Enoyl-CoA hydratase
WP8W18E11_33150	COG1960	acyl-CoA dehydrogenase activity
WP8W18E11_33160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP8W18E11_33200	COG1113	amino acid transport
WP8W18E11_33210	COG1113	amino acid transport
WP8W18E11_33220	COG0251	oxidation-reduction process
WP8W18E11_33300	COG0564	pseudouridine synthase activity
WP8W18E11_33380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WP8W18E11_33410	COG1802	Transcriptional regulator
WP8W18E11_33420	COG1448	Aminotransferase
WP8W18E11_33430	COG0277	FAD linked oxidase domain protein
WP8W18E11_33450	COG2186	Transcriptional regulator
WP8W18E11_33470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP8W18E11_33480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
WP8W18E11_33490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP8W18E11_33520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP8W18E11_33530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WP8W18E11_33540	COG1216	Glycosyl transferase, family 2
WP8W18E11_33550	COG0438	transferase activity, transferring glycosyl groups
WP8W18E11_33640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
WP8W18E11_33700	COG0728	peptidoglycan biosynthetic process
WP8W18E11_33710	COG3023	N-Acetylmuramoyl-L-alanine amidase
WP8W18E11_33820	COG0546	phosphoglycolate phosphatase activity
WP8W18E11_33830	COG1028	Short-chain dehydrogenase reductase Sdr
WP8W18E11_33870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WP8W18E11_33880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WP8W18E11_33890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP8W18E11_33900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP8W18E11_33910	COG1116	anion transmembrane transporter activity
WP8W18E11_33920	COG1309	transcriptional regulator
WP8W18E11_33930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP8W18E11_33950	COG0196	riboflavin kinase activity
WP8W18E11_33960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WP8W18E11_33980	COG1047	Peptidyl-prolyl cis-trans
WP8W18E11_34010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP8W18E11_34060	COG0583	DNA-binding transcription factor activity
WP8W18E11_34120	COG2951	lytic endotransglycosylase activity
WP8W18E11_34140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WP8W18E11_34170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP8W18E11_34190	COG0671	phosphoesterase, PA-phosphatase related
WP8W18E11_34200	COG0861	Integral membrane protein TerC family
WP8W18E11_34220	COG0754	glutathionylspermidine amidase activity
WP8W18E11_34240	COG0402	S-adenosylhomocysteine deaminase activity
WP8W18E11_34280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP8W18E11_34290	COG1230	cation diffusion facilitator family transporter
WP8W18E11_34320	COG0706	membrane insertase activity
WP8W18E11_P10070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP8W18E11_P10110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP8W18E11_P10460	COG0358	DNA primase activity
WP8W18E11_P10580	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
WP8W18E11_P10670	COG0587	DNA-directed DNA polymerase activity
WP8W18E11_P10700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP8W18E11_P10700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP8W18E11_P10800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP8W18E11_P10800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WP8W18E11_P10810	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP8W18E11_P10900	COG2194	sulfuric ester hydrolase activity
WP8W18E11_P10930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP8W18E11_P11070	COG3328	transposase activity
WP8W18E11_P11120	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
WP8W18E11_P20010	COG0753	catalase activity
WP8W18E11_P20120	COG0627	Serine hydrolase involved in the detoxification of formaldehyde