locus-tag	class	description
IEE82_00020	COG0733	neurotransmitter:sodium symporter activity
IEE82_00115	COG0656	L-ascorbic acid biosynthetic process
IEE82_00120	COG0583	DNA-binding transcription factor activity
IEE82_00180	COG2983	Belongs to the UPF0260 family
IEE82_00195	COG2116	formate transmembrane transporter activity
IEE82_00220	COG1335	isochorismatase
IEE82_00275	COG0523	cobalamin synthesis protein
IEE82_00360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IEE82_00410	COG0753	catalase activity
IEE82_00535	COG3150	esterase
IEE82_00670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IEE82_00715	COG2119	membrane
IEE82_00725	COG0426	domain, Protein
IEE82_00725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEE82_00805	COG1522	sequence-specific DNA binding
IEE82_00890	COG0351	phosphomethylpyrimidine kinase
IEE82_00890	COG0352	thiamine-phosphate diphosphorylase activity
IEE82_00890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEE82_00940	COG1012	belongs to the aldehyde dehydrogenase family
IEE82_01070	COG1733	regulation of RNA biosynthetic process
IEE82_01075	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEE82_01095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IEE82_01175	COG2329	Antibiotic biosynthesis monooxygenase
IEE82_01205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEE82_01265	COG4221	oxidoreductase activity
IEE82_01405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IEE82_01485	COG1704	LemA family
IEE82_01490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IEE82_01500	COG4969	Belongs to the N-Me-Phe pilin family
IEE82_01525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEE82_01535	COG0194	GDP metabolic process
IEE82_01585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEE82_01650	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IEE82_01670	COG1289	transmembrane transporter activity
IEE82_01785	COG0583	DNA-binding transcription factor activity
IEE82_01885	COG0513	Belongs to the DEAD box helicase family
IEE82_01895	COG1127	ABC transporter
IEE82_01900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IEE82_01930	COG0494	nUDIX hydrolase
IEE82_01960	COG1946	Acyl-CoA thioesterase
IEE82_01980	COG1959	2 iron, 2 sulfur cluster binding
IEE82_01985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEE82_01985	COG1017	nitric oxide dioxygenase activity
IEE82_02155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IEE82_02185	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IEE82_02295	COG1702	phosphate starvation-inducible protein PhoH
IEE82_02385	COG1960	acyl-CoA dehydrogenase activity
IEE82_02390	COG1309	transcriptional regulator
IEE82_02430	COG2969	positive regulation of protein catabolic process
IEE82_02440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IEE82_02830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEE82_03255	COG1690	Belongs to the RtcB family
IEE82_03275	COG1217	gtp-binding protein TYPA
IEE82_03345	COG3189	MarR family transcriptional regulator
IEE82_03350	COG2824	Alkylphosphonate utilization operon protein PhnA
IEE82_03425	COG2832	Protein of unknown function (DUF454)
IEE82_03560	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEE82_03570	COG1792	Involved in formation and maintenance of cell shape
IEE82_03580	COG0424	maF-like protein
IEE82_03640	COG2207	Transcriptional regulator
IEE82_03715	COG0745	RESPONSE REGULATOR receiver
IEE82_03780	COG0393	Putative heavy-metal-binding
IEE82_03830	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IEE82_03850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IEE82_03855	COG1733	regulation of RNA biosynthetic process
IEE82_03880	COG0321	lipoyl(octanoyl) transferase activity
IEE82_03885	COG2921	Belongs to the UPF0250 family
IEE82_03925	COG2009	succinate dehydrogenase
IEE82_04020	COG0589	response to stress
IEE82_04245	COG3811	Belongs to the UPF0386 family
IEE82_04300	COG0778	Nitroreductase
IEE82_04325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEE82_04340	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IEE82_04465	COG1136	(ABC) transporter
IEE82_04575	COG0824	Thioesterase
IEE82_04600	COG0047	phosphoribosylformylglycinamidine synthase activity
IEE82_04600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEE82_04635	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_04820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IEE82_04840	COG0583	DNA-binding transcription factor activity
IEE82_04855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IEE82_04865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IEE82_04930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEE82_04940	COG1381	Involved in DNA repair and RecF pathway recombination
IEE82_04945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IEE82_04955	COG4221	oxidoreductase activity
IEE82_05015	COG0556	nucleotide-excision repair
IEE82_05130	COG1686	Belongs to the peptidase S11 family
IEE82_05145	COG1187	pseudouridine synthase activity
IEE82_05180	COG1823	symporter activity
IEE82_05260	COG2249	NAD(P)H dehydrogenase (quinone) activity
IEE82_05290	COG1522	sequence-specific DNA binding
IEE82_05390	COG0583	DNA-binding transcription factor activity
IEE82_05445	COG2879	small protein
IEE82_05545	COG1741	Belongs to the pirin family
IEE82_05555	COG2964	Protein conserved in bacteria
IEE82_05580	COG4605	iron ion homeostasis
IEE82_05585	COG4604	ABC transporter, ATP-binding protein
IEE82_05635	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IEE82_05680	COG0302	gtp cyclohydrolase
IEE82_05725	COG0512	Glutamine amidotransferase of anthranilate synthase
IEE82_05740	COG0174	glutamine synthetase
IEE82_05785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEE82_05845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEE82_05940	COG1131	(ABC) transporter
IEE82_06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEE82_06080	COG0494	nUDIX hydrolase
IEE82_06090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IEE82_06110	COG1301	dicarboxylic acid transport
IEE82_06160	COG1690	Belongs to the RtcB family
IEE82_06165	COG1234	tRNA 3'-trailer cleavage
IEE82_06215	COG1278	Cold shock
IEE82_06230	COG0778	Nitroreductase
IEE82_06290	COG1610	YqeY-like protein
IEE82_06545	COG2186	Transcriptional regulator
IEE82_06660	COG2186	Transcriptional regulator
IEE82_06885	COG1794	racemase activity, acting on amino acids and derivatives
IEE82_06930	COG2011	ABC-type metal ion transport system permease component
IEE82_06955	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IEE82_07035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IEE82_07085	COG3658	cytochrome
IEE82_07095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEE82_07145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IEE82_07165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEE82_07315	COG1923	regulation of RNA biosynthetic process
IEE82_07345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEE82_07355	COG4302	ethanolamine ammonia-lyase activity
IEE82_07510	COG4773	Receptor
IEE82_07630	COG0824	Thioesterase
IEE82_07635	COG1454	alcohol dehydrogenase
IEE82_07810	COG3617	BRO family, N-terminal domain
IEE82_07960	COG1598	PFAM Uncharacterised protein family UPF0150
IEE82_08055	COG0511	ligase activity, forming carbon-carbon bonds
IEE82_08090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEE82_08090	COG2146	nitrite reductase [NAD(P)H] activity
IEE82_08110	COG0243	molybdopterin cofactor binding
IEE82_08115	COG0243	molybdopterin cofactor binding
IEE82_08190	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IEE82_08195	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IEE82_08280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEE82_08285	COG0575	Belongs to the CDS family
IEE82_08320	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IEE82_08335	COG2137	regulation of response to DNA damage stimulus
IEE82_08405	COG2135	peptidase activity
IEE82_08485	COG0024	Methionine aminopeptidase
IEE82_08505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IEE82_08510	COG0516	GMP reductase activity
IEE82_08510	COG0517	IMP dehydrogenase activity
IEE82_08545	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IEE82_08560	COG4890	Cyd operon protein YbgT
IEE82_08565	COG1294	oxidase, subunit
IEE82_08650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IEE82_08680	COG0446	pyridine nucleotide-disulphide oxidoreductase
IEE82_08680	COG1902	pentaerythritol trinitrate reductase activity
IEE82_08730	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IEE82_08740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEE82_08745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEE82_08755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEE82_08770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEE82_08780	COG3485	protocatechuate 3,4-dioxygenase
IEE82_08795	COG3659	wide pore channel activity
IEE82_08810	COG2391	methyltransferase activity
IEE82_08860	COG2814	Major facilitator Superfamily
IEE82_08940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEE82_08950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IEE82_08965	COG4829	muconolactone delta-isomerase
IEE82_09035	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEE82_09045	COG0789	Transcriptional regulator
IEE82_09080	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_09085	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_09090	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_09255	COG0583	DNA-binding transcription factor activity
IEE82_09270	COG2084	Dehydrogenase
IEE82_09280	COG1064	alcohol dehydrogenase
IEE82_09290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEE82_09470	COG2207	Transcriptional regulator
IEE82_09490	COG0745	RESPONSE REGULATOR receiver
IEE82_09580	COG3539	Fimbrial protein
IEE82_09605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IEE82_09630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEE82_09635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEE82_09750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEE82_09780	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_09910	COG2188	Transcriptional regulator
IEE82_09920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEE82_09925	COG1733	regulation of RNA biosynthetic process
IEE82_09945	COG0730	response to heat
IEE82_09990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEE82_09995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IEE82_10005	COG0508	dehydrogenase complex catalyzes the overall conversion of
IEE82_10015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IEE82_10350	COG1960	acyl-CoA dehydrogenase activity
IEE82_10395	COG0822	iron-sulfur transferase activity
IEE82_11005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IEE82_11025	COG0191	fructose-bisphosphate aldolase activity
IEE82_11100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEE82_11105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEE82_11150	COG2353	YceI-like domain
IEE82_11300	COG1309	transcriptional regulator
IEE82_11375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEE82_11450	COG0386	Belongs to the glutathione peroxidase family
IEE82_11520	COG0798	PFAM Bile acid sodium symporter
IEE82_11525	COG0640	Transcriptional regulator
IEE82_11580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IEE82_11630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IEE82_11675	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IEE82_11730	COG0625	glutathione transferase activity
IEE82_11760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IEE82_11810	COG0765	amino acid transport
IEE82_11965	COG1960	acyl-CoA dehydrogenase activity
IEE82_12015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IEE82_12065	COG0583	DNA-binding transcription factor activity
IEE82_12070	COG3038	cytochrome b561
IEE82_12105	COG2050	protein possibly involved in aromatic compounds catabolism
IEE82_12140	COG1024	Enoyl-CoA hydratase
IEE82_12145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEE82_12190	COG1012	belongs to the aldehyde dehydrogenase family
IEE82_12425	COG0864	Transcriptional regulator
IEE82_12445	COG1733	regulation of RNA biosynthetic process
IEE82_12470	COG1063	alcohol dehydrogenase
IEE82_12480	COG1309	transcriptional regulator
IEE82_12630	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IEE82_12695	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IEE82_12735	COG2814	Major facilitator Superfamily
IEE82_12770	COG1278	Cold shock
IEE82_12870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IEE82_12880	COG1028	Short-chain dehydrogenase reductase Sdr
IEE82_12910	COG0450	alkyl hydroperoxide reductase
IEE82_12955	COG0625	glutathione transferase activity
IEE82_13045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEE82_13065	COG0582	viral genome integration into host DNA
IEE82_13220	COG3567	Phage-associated protein, HI1409 family
IEE82_13295	COG4197	protein conserved in bacteria, prophage-related
IEE82_13300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEE82_13345	COG0527	aspartate kinase activity
IEE82_13365	COG3038	cytochrome b561
IEE82_13370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IEE82_13400	COG1741	Belongs to the pirin family
IEE82_13495	COG1024	Enoyl-CoA hydratase
IEE82_13700	COG0251	oxidation-reduction process
IEE82_13920	COG1279	arginine transmembrane transporter activity
IEE82_14030	COG2878	Part of a membrane complex involved in electron transport
IEE82_14035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEE82_14080	COG0830	nickel cation binding
IEE82_14190	COG1773	rubredoxin
IEE82_14195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEE82_14240	COG4181	ATPase activity
IEE82_14320	COG3958	Transketolase
IEE82_14360	COG2223	nitrite transmembrane transporter activity
IEE82_14375	COG0242	peptide deformylase activity
IEE82_14505	COG0523	cobalamin synthesis protein
IEE82_14515	COG1607	acyl-coa hydrolase
IEE82_14710	COG0735	belongs to the Fur family
IEE82_14765	COG2885	chlorophyll binding
IEE82_14770	COG0204	Acyl-transferase
IEE82_14815	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IEE82_14870	COG1981	membrane
IEE82_14950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IEE82_15000	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IEE82_15075	COG1652	LysM domain
IEE82_15110	COG0009	L-threonylcarbamoyladenylate synthase
IEE82_15270	COG0489	protein tyrosine kinase activity
IEE82_15375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IEE82_15445	COG0745	RESPONSE REGULATOR receiver
IEE82_15460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEE82_15520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEE82_15600	COG2814	Major facilitator Superfamily
IEE82_15610	COG0583	DNA-binding transcription factor activity
IEE82_15615	COG1063	alcohol dehydrogenase
IEE82_15655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEE82_15715	COG1214	PFAM Peptidase M22, glycoprotease
IEE82_15845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IEE82_15860	COG1764	response to oxidative stress
IEE82_15980	COG1238	metal cluster binding
IEE82_15985	COG0625	glutathione transferase activity
IEE82_16005	COG3028	Belongs to the UPF0307 family
IEE82_16010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IEE82_16145	COG0583	DNA-binding transcription factor activity
IEE82_16230	COG0440	acetolactate synthase activity
IEE82_16300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IEE82_16390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEE82_16530	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IEE82_16530	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IEE82_16560	COG4774	siderophore transport
IEE82_16730	COG0724	RNA recognition motif
IEE82_16760	COG1733	regulation of RNA biosynthetic process
IEE82_16850	COG0473	3-isopropylmalate dehydrogenase activity
IEE82_16915	COG0625	glutathione transferase activity
IEE82_16935	COG1530	ribonuclease E activity
IEE82_16940	COG0318	PFAM AMP-dependent synthetase and ligase
IEE82_17025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IEE82_17065	COG0425	Belongs to the sulfur carrier protein TusA family
IEE82_17080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEE82_17125	COG0789	Transcriptional regulator
IEE82_17180	COG2226	methyltransferase
IEE82_17315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEE82_17375	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEE82_17465	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IEE82_17500	COG0596	Alpha beta hydrolase
IEE82_17595	COG0546	phosphoglycolate phosphatase activity
IEE82_17600	COG1716	ATPase activity
IEE82_17655	COG0181	hydroxymethylbilane synthase activity
IEE82_17780	COG2197	response regulator
IEE82_17805	COG0795	lipopolysaccharide-transporting ATPase activity
IEE82_17855	COG0004	ammonium transporteR
IEE82_17860	COG0347	Belongs to the P(II) protein family
IEE82_17985	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IEE82_18015	COG2860	membrane
IEE82_18025	COG1253	flavin adenine dinucleotide binding
IEE82_18190	COG0386	Belongs to the glutathione peroxidase family
IEE82_18265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IEE82_18280	COG0281	malic enzyme
IEE82_18365	COG0271	Belongs to the BolA IbaG family
IEE82_18405	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IEE82_18405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IEE82_18405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEE82_18405	COG3321	synthase
IEE82_18445	COG1024	Enoyl-CoA hydratase
IEE82_18450	COG1024	Enoyl-CoA hydratase
IEE82_18490	COG0251	oxidation-reduction process
IEE82_18625	COG1802	Transcriptional regulator
IEE82_18680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IEE82_18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IEE82_18870	COG1116	anion transmembrane transporter activity
IEE82_18875	COG1309	transcriptional regulator
IEE82_18905	COG1047	Peptidyl-prolyl cis-trans
IEE82_19020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IEE82_19580	COG1061	Type III restriction enzyme res subunit
IEE82_19585	COG1061	Type III restriction enzyme res subunit
IEE82_19605	COG1061	Type III restriction enzyme res subunit
IEE82_19630	COG1061	Type III restriction enzyme res subunit
IEE82_19635	COG1061	Type III restriction enzyme res subunit
