locus-tag	class	description
M2J07_00090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M2J07_00125	COG0741	lytic transglycosylase activity
M2J07_00210	COG0484	heat shock protein binding
M2J07_00305	COG3853	Toxic anion resistance protein (TelA)
M2J07_00320	COG1475	DNA binding
M2J07_00385	COG1525	nuclease
M2J07_00525	COG2050	protein possibly involved in aromatic compounds catabolism
M2J07_00535	COG2814	Major facilitator Superfamily
M2J07_00540	COG0405	Gamma-glutamyltransferase
M2J07_00575	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M2J07_00690	COG1484	DNA-dependent DNA replication
M2J07_00735	COG3755	Protein conserved in bacteria
M2J07_00885	COG2026	Addiction module toxin, RelE StbE family
M2J07_00925	COG0592	DNA-directed DNA polymerase activity
M2J07_01010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M2J07_01070	COG0477	Major facilitator Superfamily
M2J07_01075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M2J07_01085	COG1595	DNA-templated transcription, initiation
M2J07_01140	COG0531	amino acid
M2J07_01145	COG2040	homocysteine
M2J07_01170	COG1309	transcriptional regulator
M2J07_01175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2J07_01180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2J07_01190	COG1607	acyl-coa hydrolase
M2J07_01200	COG0523	cobalamin synthesis protein
M2J07_01210	COG4681	YaeQ
M2J07_01220	COG0726	polysaccharide deacetylase
M2J07_01220	COG1649	PFAM Uncharacterised BCR, COG1649
M2J07_01225	COG1215	transferase activity, transferring glycosyl groups
M2J07_01235	COG1024	Enoyl-CoA hydratase
M2J07_01250	COG1414	Transcriptional regulator
M2J07_01270	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_01280	COG0446	pyridine nucleotide-disulphide oxidoreductase
M2J07_01285	COG2271	Major facilitator Superfamily
M2J07_01295	COG2267	carboxylic ester hydrolase activity
M2J07_01300	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_01315	COG0028	Belongs to the TPP enzyme family
M2J07_01325	COG0477	Major facilitator Superfamily
M2J07_01330	COG0242	peptide deformylase activity
M2J07_01335	COG2066	Belongs to the glutaminase family
M2J07_01340	COG2207	Transcriptional regulator
M2J07_01345	COG2223	nitrite transmembrane transporter activity
M2J07_01360	COG0583	DNA-binding transcription factor activity
M2J07_01365	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_01370	COG2271	Major facilitator Superfamily
M2J07_01375	COG3959	Transketolase, thiamine diphosphate binding domain
M2J07_01380	COG3958	Transketolase
M2J07_01390	COG0306	phosphate transporter
M2J07_01410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M2J07_01455	COG4181	ATPase activity
M2J07_01460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M2J07_01485	COG0583	DNA-binding transcription factor activity
M2J07_01495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2J07_01500	COG1773	rubredoxin
M2J07_01550	COG2851	Citrate transporter
M2J07_01555	COG1253	flavin adenine dinucleotide binding
M2J07_01595	COG0804	urea catabolic process
M2J07_01605	COG0830	nickel cation binding
M2J07_01620	COG0742	ribosomal rna small subunit methyltransferase
M2J07_01625	COG0768	penicillin binding
M2J07_01650	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M2J07_01655	COG2878	Part of a membrane complex involved in electron transport
M2J07_01660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M2J07_01670	COG3384	dioxygenase
M2J07_01695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M2J07_02070	COG2194	sulfuric ester hydrolase activity
M2J07_02110	COG0006	proline dipeptidase activity
M2J07_02115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2J07_02120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2J07_02140	COG1279	arginine transmembrane transporter activity
M2J07_02145	COG0583	DNA-binding transcription factor activity
M2J07_02185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M2J07_02190	COG0741	lytic transglycosylase activity
M2J07_02190	COG0741	lytic transglycosylase activity
M2J07_02190	COG1388	LysM domain
M2J07_02190	COG1388	LysM domain
M2J07_02200	COG4174	ABC transporter (Permease)
M2J07_02205	COG4239	(ABC) transporter, permease
M2J07_02210	COG4172	Belongs to the ABC transporter superfamily
M2J07_02230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M2J07_02240	COG4251	negative regulation of phosphorylation
M2J07_02240	COG3706	GGDEF domain
M2J07_02240	COG2203	Gaf domain
M2J07_02240	COG5001	Diguanylate cyclase
M2J07_02250	COG0446	pyridine nucleotide-disulphide oxidoreductase
M2J07_02250	COG1902	pentaerythritol trinitrate reductase activity
M2J07_02265	COG4269	membrane
M2J07_02295	COG3209	COG3209 Rhs family protein
M2J07_02335	COG1113	amino acid transport
M2J07_02395	COG2072	flavoprotein involved in K transport
M2J07_02405	COG2252	PERMEase
M2J07_02410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M2J07_02415	COG3038	cytochrome b561
M2J07_02425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M2J07_02435	COG0527	aspartate kinase activity
M2J07_02445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M2J07_02455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M2J07_02470	COG0667	Aldo Keto reductase
M2J07_02485	COG1765	OsmC-like protein
M2J07_02500	COG0542	response to heat
M2J07_02535	COG2885	chlorophyll binding
M2J07_02545	COG0625	glutathione transferase activity
M2J07_02550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M2J07_02570	COG3634	alkyl hydroperoxide reductase activity
M2J07_02580	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M2J07_02590	COG0450	alkyl hydroperoxide reductase
M2J07_02595	COG1643	Atp-dependent helicase
M2J07_02610	COG2814	Major facilitator Superfamily
M2J07_02615	COG3135	benzoate transporter
M2J07_02620	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_02625	COG0633	Ferredoxin
M2J07_02625	COG0543	2 iron, 2 sulfur cluster binding
M2J07_02635	COG4638	Rieske (2fe-2S)
M2J07_02645	COG0583	DNA-binding transcription factor activity
M2J07_02655	COG2871	sodium ion transport
M2J07_02740	COG1570	exodeoxyribonuclease VII activity
M2J07_02770	COG1280	lysine exporter protein (LysE YggA)
M2J07_02775	COG1278	Cold shock
M2J07_02810	COG2814	Major facilitator Superfamily
M2J07_02845	COG0517	IMP dehydrogenase activity
M2J07_02845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M2J07_02850	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M2J07_02860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M2J07_02865	COG1137	ATPase activity
M2J07_02870	COG1538	Outer membrane efflux protein
M2J07_02900	COG4122	O-methyltransferase activity
M2J07_02910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M2J07_02925	COG1522	sequence-specific DNA binding
M2J07_02930	COG5006	permease, DMT superfamily
M2J07_02940	COG1560	Kdo2-lipid A biosynthetic process
M2J07_02955	COG2814	Major facilitator Superfamily
M2J07_02975	COG1250	3-hydroxyacyl-CoA dehydrogenase
M2J07_03025	COG0583	DNA-binding transcription factor activity
M2J07_03030	COG1914	H( )-stimulated, divalent metal cation uptake system
M2J07_03050	COG4770	biotin carboxylase activity
M2J07_03055	COG0038	chloride channel
M2J07_03075	COG1309	transcriptional regulator
M2J07_03085	COG1063	alcohol dehydrogenase
M2J07_03100	COG0439	Biotin carboxylase
M2J07_03105	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2J07_03125	COG0864	Transcriptional regulator
M2J07_03135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M2J07_03140	COG1116	anion transmembrane transporter activity
M2J07_03260	COG0590	tRNA wobble adenosine to inosine editing
M2J07_03265	COG2807	transmembrane transport
M2J07_03280	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M2J07_03295	COG0789	Transcriptional regulator
M2J07_03305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M2J07_03325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2J07_03335	COG0446	pyridine nucleotide-disulphide oxidoreductase
M2J07_03350	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_03355	COG0531	amino acid
M2J07_03360	COG1760	l-serine dehydratase
M2J07_03365	COG2030	dehydratase
M2J07_03365	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_03370	COG3396	Phenylacetate-CoA oxygenase
M2J07_03375	COG3460	Phenylacetate-CoA oxygenase
M2J07_03380	COG3396	Phenylacetate-CoA oxygenase
M2J07_03385	COG2151	metal-sulfur cluster biosynthetic enzyme
M2J07_03390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2J07_03395	COG1024	Enoyl-CoA hydratase
M2J07_03400	COG1024	Enoyl-CoA hydratase
M2J07_03405	COG1250	3-hydroxyacyl-CoA dehydrogenase
M2J07_03410	COG0183	Belongs to the thiolase family
M2J07_03415	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M2J07_03420	COG3327	negative regulation of DNA-templated transcription, initiation
M2J07_03430	COG2050	protein possibly involved in aromatic compounds catabolism
M2J07_03465	COG0753	catalase activity
M2J07_03470	COG3038	cytochrome b561
M2J07_03520	COG1132	(ABC) transporter
M2J07_03565	COG1132	(ABC) transporter
M2J07_03620	COG0488	(ABC) transporter
M2J07_03625	COG3173	Aminoglycoside phosphotransferase
M2J07_03635	COG2433	Pfam Transposase IS66
M2J07_03670	COG2204	response regulator
M2J07_03675	COG3852	Histidine kinase
M2J07_03695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M2J07_03700	COG0575	Belongs to the CDS family
M2J07_03735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M2J07_03750	COG2137	regulation of response to DNA damage stimulus
M2J07_03760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M2J07_03765	COG1011	Hydrolase
M2J07_03790	COG1522	sequence-specific DNA binding
M2J07_03800	COG1113	amino acid transport
M2J07_03820	COG0659	secondary active sulfate transmembrane transporter activity
M2J07_03840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M2J07_03855	COG0640	Transcriptional regulator
M2J07_03860	COG0798	PFAM Bile acid sodium symporter
M2J07_03865	COG0583	DNA-binding transcription factor activity
M2J07_03880	COG3634	alkyl hydroperoxide reductase activity
M2J07_03920	COG0436	Aminotransferase
M2J07_03930	COG0386	Belongs to the glutathione peroxidase family
M2J07_03970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M2J07_03995	COG0012	GTP binding
M2J07_04000	COG2011	ABC-type metal ion transport system permease component
M2J07_04005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M2J07_04015	COG1464	Belongs to the NlpA lipoprotein family
M2J07_04045	COG0765	amino acid transport
M2J07_04050	COG0765	amino acid transport
M2J07_04055	COG1126	abc transporter atp-binding protein
M2J07_04065	COG1522	sequence-specific DNA binding
M2J07_04080	COG1309	transcriptional regulator
M2J07_04110	COG0583	DNA-binding transcription factor activity
M2J07_04120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M2J07_04130	COG0697	spore germination
M2J07_04155	COG3121	Chaperone
M2J07_04160	COG3539	Fimbrial protein
M2J07_04185	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M2J07_04185	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M2J07_04230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M2J07_04240	COG2353	YceI-like domain
M2J07_04250	COG3698	Phosphodiester glycosidase
M2J07_04265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M2J07_04270	COG0506	proline dehydrogenase activity
M2J07_04270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M2J07_04270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M2J07_04280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2J07_04285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M2J07_04305	COG1132	(ABC) transporter
M2J07_04310	COG3122	Protein conserved in bacteria
M2J07_04315	COG3619	membrane
M2J07_04325	COG0640	Transcriptional regulator
M2J07_04335	COG2850	peptidyl-arginine hydroxylation
M2J07_04340	COG0424	maF-like protein
M2J07_04360	COG0191	fructose-bisphosphate aldolase activity
M2J07_04365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M2J07_04380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M2J07_04390	COG1192	Involved in chromosome partitioning
M2J07_04395	COG1475	DNA binding
M2J07_04400	COG0811	peptide transport
M2J07_04410	COG1132	(ABC) transporter
M2J07_04415	COG1663	tetraacyldisaccharide 4'-kinase activity
M2J07_04435	COG0084	hydrolase, TatD family'
M2J07_04500	COG0776	regulation of translation
M2J07_04530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M2J07_04535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M2J07_04585	COG0339	signal peptide processing
M2J07_04595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M2J07_04630	COG0702	epimerase
M2J07_04635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M2J07_04655	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M2J07_04685	COG0316	Belongs to the HesB IscA family
M2J07_04690	COG0822	iron-sulfur transferase activity
M2J07_04715	COG0776	regulation of translation
M2J07_04720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M2J07_04725	COG2207	Transcriptional regulator
M2J07_04730	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M2J07_04735	COG1960	acyl-CoA dehydrogenase activity
M2J07_04740	COG1960	acyl-CoA dehydrogenase activity
M2J07_04755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M2J07_04775	COG4264	IucA IucC family
M2J07_04780	COG4264	IucA IucC family
M2J07_04820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M2J07_04835	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M2J07_04855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M2J07_04860	COG0730	response to heat
M2J07_04880	COG4773	Receptor
M2J07_04885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M2J07_04900	COG1131	(ABC) transporter
M2J07_04905	COG0842	Transport permease protein
M2J07_04910	COG0842	Transport permease protein
M2J07_04970	COG2226	methyltransferase
M2J07_04995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M2J07_05030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M2J07_05040	COG0133	tryptophan synthase activity
M2J07_05055	COG3706	GGDEF domain
M2J07_05070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M2J07_05075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M2J07_05080	COG0022	dehydrogenase e1 component
M2J07_05085	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2J07_05090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2J07_05100	COG1063	alcohol dehydrogenase
M2J07_05105	COG3781	membrane
M2J07_05115	COG3453	Protein conserved in bacteria
M2J07_05115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2J07_05130	COG0730	response to heat
M2J07_05145	COG2207	Transcriptional regulator
M2J07_05145	COG3708	Transcriptional regulator
M2J07_05150	COG1733	regulation of RNA biosynthetic process
M2J07_05155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M2J07_05165	COG2188	Transcriptional regulator
M2J07_05180	COG4521	taurine ABC transporter
M2J07_05185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M2J07_05205	COG0477	Major facilitator Superfamily
M2J07_05215	COG1027	Aspartate ammonia-lyase
M2J07_05230	COG0583	DNA-binding transcription factor activity
M2J07_05235	COG0583	DNA-binding transcription factor activity
M2J07_05240	COG0183	Belongs to the thiolase family
M2J07_05245	COG2031	fatty acid transporter
M2J07_05250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M2J07_05260	COG0583	DNA-binding transcription factor activity
M2J07_05270	COG2610	gluconate transmembrane transporter activity
M2J07_05275	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_05285	COG2207	Transcriptional regulator
M2J07_05300	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_05325	COG0543	2 iron, 2 sulfur cluster binding
M2J07_05325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2J07_05330	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M2J07_05335	COG4638	Rieske (2fe-2S)
M2J07_05345	COG0725	ABC transporter, periplasmic molybdate-binding protein
M2J07_05350	COG4149	molybdate abc transporter
M2J07_05355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M2J07_05360	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_05365	COG1535	isochorismatase
M2J07_05365	COG3433	isochorismatase activity
M2J07_05425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M2J07_05440	COG0753	catalase activity
M2J07_05450	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M2J07_05480	COG3539	Fimbrial protein
M2J07_05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2J07_05520	COG2072	flavoprotein involved in K transport
M2J07_05530	COG1538	Outer membrane efflux protein
M2J07_05535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M2J07_05540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_05545	COG0745	RESPONSE REGULATOR receiver
M2J07_05550	COG2205	protein histidine kinase activity
M2J07_05560	COG2207	Transcriptional regulator
M2J07_05575	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_05625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M2J07_05745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M2J07_05765	COG1120	ATPase activity
M2J07_05770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2J07_05780	COG1064	alcohol dehydrogenase
M2J07_05795	COG2207	Transcriptional regulator
M2J07_05800	COG2084	Dehydrogenase
M2J07_05810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M2J07_05815	COG0583	DNA-binding transcription factor activity
M2J07_05825	COG0129	dihydroxy-acid dehydratase activity
M2J07_05830	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_05845	COG1566	PFAM secretion protein HlyD family protein
M2J07_05875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M2J07_05905	COG0583	DNA-binding transcription factor activity
M2J07_05920	COG2188	Transcriptional regulator
M2J07_05950	COG3210	domain, Protein
M2J07_05955	COG2831	hemolysin activation secretion protein
M2J07_05965	COG1473	amidohydrolase
M2J07_05975	COG0475	glutathione-regulated potassium exporter activity
M2J07_05975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M2J07_05985	COG0583	DNA-binding transcription factor activity
M2J07_05990	COG1335	isochorismatase
M2J07_06000	COG1309	transcriptional regulator
M2J07_06030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M2J07_06040	COG0446	pyridine nucleotide-disulphide oxidoreductase
M2J07_06040	COG1902	pentaerythritol trinitrate reductase activity
M2J07_06045	COG1846	Transcriptional regulator
M2J07_06065	COG0753	catalase activity
M2J07_06080	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_06095	COG3162	membrane
M2J07_06105	COG3829	transcription factor binding
M2J07_06110	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_06115	COG1960	acyl-CoA dehydrogenase activity
M2J07_06135	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_06155	COG2186	Transcriptional regulator
M2J07_06165	COG0583	DNA-binding transcription factor activity
M2J07_06170	COG4948	Mandelate Racemase Muconate Lactonizing
M2J07_06175	COG4829	muconolactone delta-isomerase
M2J07_06185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M2J07_06190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M2J07_06195	COG0183	Belongs to the thiolase family
M2J07_06200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M2J07_06210	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_06220	COG3733	amine oxidase
M2J07_06230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M2J07_06240	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_06250	COG4638	Rieske (2fe-2S)
M2J07_06270	COG0154	amidase activity
M2J07_06280	COG2814	Major facilitator Superfamily
M2J07_06305	COG1960	acyl-CoA dehydrogenase activity
M2J07_06310	COG0583	DNA-binding transcription factor activity
M2J07_06315	COG1414	Transcriptional regulator
M2J07_06330	COG2391	methyltransferase activity
M2J07_06340	COG4993	Dehydrogenase
M2J07_06345	COG3659	wide pore channel activity
M2J07_06350	COG3420	alginic acid biosynthetic process
M2J07_06355	COG0710	3-dehydroquinate dehydratase activity
M2J07_06360	COG3485	protocatechuate 3,4-dioxygenase
M2J07_06365	COG3485	protocatechuate 3,4-dioxygenase
M2J07_06370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M2J07_06375	COG2271	Major facilitator Superfamily
M2J07_06380	COG0596	Alpha beta hydrolase
M2J07_06385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M2J07_06390	COG0183	Belongs to the thiolase family
M2J07_06395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M2J07_06400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M2J07_06410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M2J07_06415	COG2323	membrane
M2J07_06460	COG1902	pentaerythritol trinitrate reductase activity
M2J07_06460	COG0446	pyridine nucleotide-disulphide oxidoreductase
M2J07_06485	COG0542	response to heat
M2J07_06490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M2J07_06520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M2J07_06525	COG0569	domain protein
M2J07_06530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M2J07_06545	COG4774	siderophore transport
M2J07_06550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M2J07_06560	COG1585	Membrane protein implicated in regulation of membrane protease activity
M2J07_06575	COG1294	oxidase, subunit
M2J07_06580	COG4890	Cyd operon protein YbgT
M2J07_06595	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M2J07_06605	COG0552	protein localization to endoplasmic reticulum
M2J07_06630	COG0517	IMP dehydrogenase activity
M2J07_06630	COG0516	GMP reductase activity
M2J07_06635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M2J07_06640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M2J07_06650	COG0583	DNA-binding transcription factor activity
M2J07_06655	COG0024	Methionine aminopeptidase
M2J07_06685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2J07_06685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M2J07_06690	COG1105	Belongs to the carbohydrate kinase PfkB family
M2J07_06695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2J07_06695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M2J07_06695	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M2J07_06715	COG3300	MHYT domain
M2J07_06715	COG5001	Diguanylate cyclase
M2J07_06730	COG2135	peptidase activity
M2J07_06785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M2J07_06790	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M2J07_06810	COG0697	spore germination
M2J07_06815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2J07_06825	COG0303	'Molybdopterin
M2J07_06830	COG0521	Mo-molybdopterin cofactor biosynthetic process
M2J07_06830	COG0315	cyclic pyranopterin monophosphate synthase activity
M2J07_06845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M2J07_06850	COG0243	molybdopterin cofactor binding
M2J07_06860	COG0243	molybdopterin cofactor binding
M2J07_06865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2J07_06870	COG2146	nitrite reductase [NAD(P)H] activity
M2J07_06870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2J07_06880	COG0745	RESPONSE REGULATOR receiver
M2J07_06885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2J07_06885	COG1116	anion transmembrane transporter activity
M2J07_06905	COG0511	ligase activity, forming carbon-carbon bonds
M2J07_06920	COG2814	Major facilitator Superfamily
M2J07_07010	COG1598	PFAM Uncharacterised protein family UPF0150
M2J07_07115	COG5410	chromosome segregation
M2J07_07290	COG0069	glutamate synthase activity
M2J07_07310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M2J07_07320	COG1454	alcohol dehydrogenase
M2J07_07325	COG0824	Thioesterase
M2J07_07335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M2J07_07350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2J07_07355	COG2030	dehydratase
M2J07_07365	COG0183	Belongs to the thiolase family
M2J07_07375	COG0583	DNA-binding transcription factor activity
M2J07_07380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M2J07_07390	COG1522	sequence-specific DNA binding
M2J07_07395	COG3135	benzoate transporter
M2J07_07405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M2J07_07430	COG0589	response to stress
M2J07_07435	COG0488	(ABC) transporter
M2J07_07455	COG4773	Receptor
M2J07_07490	COG0668	transmembrane transport
M2J07_07500	COG1309	transcriptional regulator
M2J07_07520	COG1605	Chorismate mutase
M2J07_07530	COG4221	oxidoreductase activity
M2J07_07540	COG0308	aminopeptidase N
M2J07_07560	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M2J07_07570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M2J07_07575	COG1454	alcohol dehydrogenase
M2J07_07595	COG0531	amino acid
M2J07_07600	COG4303	Ethanolamine ammonia lyase large subunit
M2J07_07605	COG4302	ethanolamine ammonia-lyase activity
M2J07_07610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M2J07_07610	COG0519	Catalyzes the synthesis of GMP from XMP
M2J07_07615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M2J07_07625	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M2J07_07640	COG0697	spore germination
M2J07_07645	COG1923	regulation of RNA biosynthetic process
M2J07_07655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M2J07_07660	COG0802	atpase or kinase
M2J07_07680	COG1187	pseudouridine synthase activity
M2J07_07695	COG0583	DNA-binding transcription factor activity
M2J07_07710	COG2814	Major facilitator Superfamily
M2J07_07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M2J07_07740	COG0729	surface antigen
M2J07_07760	COG0174	glutamine synthetase
M2J07_07765	COG0745	RESPONSE REGULATOR receiver
M2J07_07770	COG2205	protein histidine kinase activity
M2J07_07780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M2J07_07785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M2J07_07810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M2J07_07815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M2J07_07820	COG1960	acyl-CoA dehydrogenase activity
M2J07_07835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2J07_07840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M2J07_07860	COG0583	DNA-binding transcription factor activity
M2J07_07875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2J07_07885	COG3658	cytochrome
M2J07_07890	COG1215	transferase activity, transferring glycosyl groups
M2J07_07895	COG0726	polysaccharide deacetylase
M2J07_07895	COG1649	PFAM Uncharacterised BCR, COG1649
M2J07_07920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M2J07_07925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M2J07_07935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M2J07_07960	COG0305	Participates in initiation and elongation during chromosome replication
M2J07_07965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M2J07_07975	COG1305	Transglutaminase-like
M2J07_07985	COG2308	Evidence 4 Homologs of previously reported genes of
M2J07_08015	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M2J07_08020	COG0138	bifunctional purine biosynthesis protein purh
M2J07_08025	COG0151	Belongs to the GarS family
M2J07_08030	COG1464	Belongs to the NlpA lipoprotein family
M2J07_08035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M2J07_08040	COG2011	ABC-type metal ion transport system permease component
M2J07_08045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2J07_08055	COG1301	dicarboxylic acid transport
M2J07_08085	COG1794	racemase activity, acting on amino acids and derivatives
M2J07_08095	COG3008	intermembrane lipid transfer
M2J07_08095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M2J07_08100	COG2995	paraquat-inducible protein a
M2J07_08110	COG2985	domain, Protein
M2J07_08140	COG0477	Major facilitator Superfamily
M2J07_08190	COG2186	Transcriptional regulator
M2J07_08200	COG0786	glutamate:sodium symporter activity
M2J07_08205	COG3243	poly(R)-hydroxyalkanoic acid synthase
M2J07_08230	COG3111	PFAM Bacterial OB fold (BOF) protein
M2J07_08330	COG1610	YqeY-like protein
M2J07_08335	COG4783	chaperone-mediated protein folding
M2J07_08360	COG1286	toxin biosynthetic process
M2J07_08390	COG0778	Nitroreductase
M2J07_08400	COG0513	Belongs to the DEAD box helicase family
M2J07_08425	COG2363	Small membrane protein
M2J07_08455	COG1234	tRNA 3'-trailer cleavage
M2J07_08460	COG2195	Cleaves the N-terminal amino acid of tripeptides
M2J07_08470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M2J07_08480	COG2819	hydrolase of the alpha beta superfamily
M2J07_08485	COG1960	acyl-CoA dehydrogenase activity
M2J07_08490	COG1301	dicarboxylic acid transport
M2J07_08495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M2J07_08500	COG3139	Protein of unknown function (DUF1315)
M2J07_08505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M2J07_08510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M2J07_08520	COG0494	nUDIX hydrolase
M2J07_08530	COG0642	Histidine kinase
M2J07_08545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M2J07_08555	COG1720	tRNA m6t6A37 methyltransferase activity
M2J07_08570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2J07_08575	COG0826	peptidase U32
M2J07_08580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M2J07_08590	COG4598	ABC transporter
M2J07_08595	COG4160	amino acid transport
M2J07_08600	COG4215	(ABC) transporter
M2J07_08625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_08670	COG1131	(ABC) transporter
M2J07_08675	COG0842	Transport permease protein
M2J07_08690	COG0772	Belongs to the SEDS family
M2J07_08695	COG2951	lytic endotransglycosylase activity
M2J07_08720	COG2207	Transcriptional regulator
M2J07_08735	COG0052	Belongs to the universal ribosomal protein uS2 family
M2J07_08740	COG0024	Methionine aminopeptidase
M2J07_08750	COG2223	nitrite transmembrane transporter activity
M2J07_08760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2J07_08765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M2J07_08770	COG1960	acyl-CoA dehydrogenase activity
M2J07_08785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M2J07_08790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M2J07_08795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M2J07_08815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2J07_08820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M2J07_08825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M2J07_08860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M2J07_08870	COG0174	glutamine synthetase
M2J07_08885	COG0512	Glutamine amidotransferase of anthranilate synthase
M2J07_08890	COG0308	aminopeptidase N
M2J07_08920	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M2J07_08930	COG0302	gtp cyclohydrolase
M2J07_08950	COG3739	integral membrane protein
M2J07_08965	COG1169	isochorismate synthase
M2J07_08975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M2J07_08980	COG1132	(ABC) transporter
M2J07_08985	COG1132	(ABC) transporter
M2J07_09000	COG3433	isochorismatase activity
M2J07_09000	COG1535	isochorismatase
M2J07_09005	COG1021	2,3-dihydroxybenzoate-AMP ligase
M2J07_09010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2J07_09020	COG4774	siderophore transport
M2J07_09025	COG4607	ABC-type enterochelin transport system periplasmic component
M2J07_09030	COG4604	ABC transporter, ATP-binding protein
M2J07_09035	COG4605	iron ion homeostasis
M2J07_09040	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M2J07_09045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2J07_09060	COG2964	Protein conserved in bacteria
M2J07_09070	COG1741	Belongs to the pirin family
M2J07_09090	COG1309	transcriptional regulator
M2J07_09100	COG4948	Mandelate Racemase Muconate Lactonizing
M2J07_09105	COG2814	Major facilitator Superfamily
M2J07_09140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M2J07_09140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M2J07_09145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2J07_09155	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_09165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2J07_09170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2J07_09175	COG0583	DNA-binding transcription factor activity
M2J07_09180	COG1113	amino acid transport
M2J07_09200	COG2508	Transcriptional regulator
M2J07_09200	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M2J07_09235	COG2879	small protein
M2J07_09240	COG1966	Carbon starvation protein
M2J07_09285	COG1067	ATP-dependent peptidase activity
M2J07_09290	COG0583	DNA-binding transcription factor activity
M2J07_09315	COG1686	Belongs to the peptidase S11 family
M2J07_09320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M2J07_09355	COG0616	signal peptide processing
M2J07_09360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M2J07_09370	COG0573	inorganic phosphate transmembrane transporter activity
M2J07_09375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M2J07_09380	COG1113	amino acid transport
M2J07_09385	COG3961	Belongs to the TPP enzyme family
M2J07_09390	COG1522	sequence-specific DNA binding
M2J07_09400	COG0076	glutamate decarboxylase activity
M2J07_09405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M2J07_09415	COG1309	transcriptional regulator
M2J07_09430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2J07_09465	COG0352	thiamine-phosphate diphosphorylase activity
M2J07_09490	COG0612	Peptidase, M16
M2J07_09500	COG1823	symporter activity
M2J07_09505	COG0583	DNA-binding transcription factor activity
M2J07_09510	COG0477	Major facilitator Superfamily
M2J07_09535	COG1187	pseudouridine synthase activity
M2J07_09550	COG1686	Belongs to the peptidase S11 family
M2J07_09555	COG1252	NADH dehydrogenase
M2J07_09565	COG0415	Belongs to the DNA photolyase family
M2J07_09580	COG1215	transferase activity, transferring glycosyl groups
M2J07_09610	COG2070	2-Nitropropane dioxygenase
M2J07_09665	COG0556	nucleotide-excision repair
M2J07_09685	COG0436	Aminotransferase
M2J07_09715	COG4221	oxidoreductase activity
M2J07_09725	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M2J07_09730	COG1381	Involved in DNA repair and RecF pathway recombination
M2J07_09740	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M2J07_09755	COG0681	Belongs to the peptidase S26 family
M2J07_09770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M2J07_09790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M2J07_09795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M2J07_09800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M2J07_09810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M2J07_09815	COG4208	sulfate ABC transporter
M2J07_09820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M2J07_09825	COG0583	DNA-binding transcription factor activity
M2J07_09830	COG4625	pathogenesis
M2J07_09845	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M2J07_09860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M2J07_09870	COG1056	cytidyltransferase-related domain
M2J07_09870	COG1051	belongs to the nudix hydrolase family
M2J07_09875	COG1024	Enoyl-CoA hydratase
M2J07_09885	COG2814	Major facilitator Superfamily
M2J07_09890	COG0047	phosphoribosylformylglycinamidine synthase activity
M2J07_09890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M2J07_09910	COG1473	amidohydrolase
M2J07_09915	COG0824	Thioesterase
M2J07_09935	COG0823	Involved in the tonB-independent uptake of proteins
M2J07_09955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M2J07_09990	COG0628	permease
M2J07_10000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M2J07_10005	COG0596	Alpha beta hydrolase
M2J07_10010	COG0616	signal peptide processing
M2J07_10010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M2J07_10020	COG0658	competence protein
M2J07_10020	COG2333	competence protein COMEC
M2J07_10025	COG1136	(ABC) transporter
M2J07_10030	COG4591	ABC-type transport system involved in lipoprotein release permease component
M2J07_10065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_10085	COG0463	Glycosyl transferase, family 2
M2J07_10115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M2J07_10120	COG1280	lysine exporter protein (LysE YggA)
M2J07_10130	COG0019	diaminopimelate decarboxylase activity
M2J07_10140	COG1113	amino acid transport
M2J07_10155	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M2J07_10165	COG3339	Conserved Protein
M2J07_10170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M2J07_10175	COG0243	molybdopterin cofactor binding
M2J07_10180	COG1929	Belongs to the glycerate kinase type-1 family
M2J07_10195	COG0778	Nitroreductase
M2J07_10225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2J07_10240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M2J07_10260	COG0741	lytic transglycosylase activity
M2J07_10280	COG0584	glycerophosphoryl diester phosphodiesterase
M2J07_10285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2J07_10310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M2J07_10315	COG1597	lipid kinase activity
M2J07_10330	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M2J07_10335	COG0477	Major facilitator Superfamily
M2J07_10385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M2J07_10390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M2J07_10415	COG0505	Belongs to the CarA family
M2J07_10435	COG0589	response to stress
M2J07_10450	COG2843	Capsule synthesis protein
M2J07_10470	COG2321	neutral zinc metallopeptidase
M2J07_10475	COG2354	Protein conserved in bacteria
M2J07_10495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M2J07_10520	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M2J07_10525	COG1053	succinate dehydrogenase
M2J07_10530	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M2J07_10535	COG2009	succinate dehydrogenase
M2J07_10575	COG2921	Belongs to the UPF0250 family
M2J07_10580	COG0321	lipoyl(octanoyl) transferase activity
M2J07_10595	COG0531	amino acid
M2J07_10605	COG1733	regulation of RNA biosynthetic process
M2J07_10610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M2J07_10615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M2J07_10615	COG1648	precorrin-2 dehydrogenase activity
M2J07_10630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M2J07_10660	COG0671	phosphoesterase, PA-phosphatase related
M2J07_10665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_10675	COG1538	Outer membrane efflux protein
M2J07_10680	COG0393	Putative heavy-metal-binding
M2J07_10685	COG0393	Putative heavy-metal-binding
M2J07_10695	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_10705	COG0525	valine-tRNA ligase activity
M2J07_10725	COG0583	DNA-binding transcription factor activity
M2J07_10730	COG0004	ammonium transporteR
M2J07_10740	COG0642	Histidine kinase
M2J07_10745	COG0745	RESPONSE REGULATOR receiver
M2J07_10750	COG2194	sulfuric ester hydrolase activity
M2J07_10775	COG1752	Esterase of the alpha-beta hydrolase superfamily
M2J07_10790	COG2315	Protein conserved in bacteria
M2J07_10795	COG0142	geranyltranstransferase activity
M2J07_10800	COG2828	Protein conserved in bacteria
M2J07_10805	COG1113	amino acid transport
M2J07_10825	COG2207	Transcriptional regulator
M2J07_10850	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2J07_10860	COG0560	Phosphoserine phosphatase
M2J07_10870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M2J07_10880	COG1530	ribonuclease E activity
M2J07_10885	COG0424	maF-like protein
M2J07_10890	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M2J07_10895	COG1792	Involved in formation and maintenance of cell shape
M2J07_10900	COG1077	Cell shape determining protein MreB Mrl
M2J07_10905	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M2J07_10915	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M2J07_10945	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M2J07_10950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M2J07_10955	COG1752	Esterase of the alpha-beta hydrolase superfamily
M2J07_10960	COG1115	amino acid carrier protein
M2J07_10980	COG2814	Major facilitator Superfamily
M2J07_10985	COG1289	transmembrane transporter activity
M2J07_10995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M2J07_11035	COG1376	ErfK ybiS ycfS ynhG family protein
M2J07_11040	COG2832	Protein of unknown function (DUF454)
M2J07_11050	COG5510	response to toxic substance
M2J07_11070	COG0840	transmembrane signaling receptor activity
M2J07_11110	COG3422	double-strand break repair
M2J07_11115	COG2824	Alkylphosphonate utilization operon protein PhnA
M2J07_11120	COG3189	MarR family transcriptional regulator
M2J07_11130	COG0354	folic acid binding
M2J07_11135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M2J07_11145	COG0679	Auxin Efflux Carrier
M2J07_11150	COG1902	pentaerythritol trinitrate reductase activity
M2J07_11155	COG4772	TonB-dependent receptor
M2J07_11160	COG2094	Belongs to the DNA glycosylase MPG family
M2J07_11185	COG1217	gtp-binding protein TYPA
M2J07_11190	COG2233	PERMEase
M2J07_11200	COG0833	amino acid
M2J07_11205	COG1690	Belongs to the RtcB family
M2J07_11215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M2J07_11215	COG2885	chlorophyll binding
M2J07_11225	COG0183	Belongs to the thiolase family
M2J07_11245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M2J07_11265	COG2207	Transcriptional regulator
M2J07_11270	COG0183	Belongs to the thiolase family
M2J07_11300	COG1272	protein, Hemolysin III
M2J07_11305	COG0477	Major facilitator Superfamily
M2J07_11320	COG0450	alkyl hydroperoxide reductase
M2J07_11340	COG0285	dihydrofolate synthase activity
M2J07_11390	COG2096	Adenosyltransferase
M2J07_11410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M2J07_11415	COG0745	RESPONSE REGULATOR receiver
M2J07_11420	COG2205	protein histidine kinase activity
M2J07_11430	COG1960	acyl-CoA dehydrogenase activity
M2J07_11435	COG1960	acyl-CoA dehydrogenase activity
M2J07_11440	COG0583	DNA-binding transcription factor activity
M2J07_11445	COG0625	glutathione transferase activity
M2J07_11510	COG0438	transferase activity, transferring glycosyl groups
M2J07_11515	COG0463	Glycosyl transferase, family 2
M2J07_11520	COG0726	polysaccharide deacetylase
M2J07_11540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M2J07_11545	COG2205	protein histidine kinase activity
M2J07_11595	COG1862	Preprotein translocase
M2J07_11605	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M2J07_11610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M2J07_11620	COG3781	membrane
M2J07_11625	COG0613	PHP domain protein
M2J07_11635	COG2350	Protein conserved in bacteria
M2J07_11665	COG1607	acyl-coa hydrolase
M2J07_11725	COG2199	diguanylate cyclase activity
M2J07_11735	COG1408	metallophosphoesterase
M2J07_11740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M2J07_11750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M2J07_11775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M2J07_11780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M2J07_11795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M2J07_11805	COG2969	positive regulation of protein catabolic process
M2J07_11825	COG1960	acyl-CoA dehydrogenase activity
M2J07_11830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M2J07_11845	COG1309	transcriptional regulator
M2J07_11850	COG1960	acyl-CoA dehydrogenase activity
M2J07_11895	COG1183	phosphatidylcholine synthase activity
M2J07_11900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M2J07_11930	COG0739	heme binding
M2J07_11930	COG0741	lytic transglycosylase activity
M2J07_11930	COG1196	nuclear chromosome segregation
M2J07_11940	COG1702	phosphate starvation-inducible protein PhoH
M2J07_11975	COG1295	ribonuclease BN
M2J07_11980	COG0697	spore germination
M2J07_11985	COG2169	Transcriptional regulator
M2J07_11990	COG0179	Fumarylacetoacetate (FAA) hydrolase
M2J07_12035	COG0557	exoribonuclease II activity
M2J07_12040	COG0339	signal peptide processing
M2J07_12045	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M2J07_12075	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M2J07_12080	COG1960	acyl-CoA dehydrogenase activity
M2J07_12235	COG0626	cystathionine gamma-synthase activity
M2J07_12240	COG0433	COG0433 Predicted ATPase
M2J07_12245	COG1017	nitric oxide dioxygenase activity
M2J07_12245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M2J07_12250	COG1959	2 iron, 2 sulfur cluster binding
M2J07_12265	COG1301	dicarboxylic acid transport
M2J07_12270	COG1946	Acyl-CoA thioesterase
M2J07_12290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M2J07_12295	COG1040	competence protein
M2J07_12300	COG0494	nUDIX hydrolase
M2J07_12310	COG0598	Magnesium transport protein CorA
M2J07_12320	COG2854	intermembrane phospholipid transfer
M2J07_12330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M2J07_12335	COG1127	ABC transporter
M2J07_12345	COG0513	Belongs to the DEAD box helicase family
M2J07_12365	COG0408	coproporphyrinogen oxidase activity
M2J07_12380	COG1960	acyl-CoA dehydrogenase activity
M2J07_12390	COG1983	PspC domain protein
M2J07_12395	COG0517	IMP dehydrogenase activity
M2J07_12440	COG0583	DNA-binding transcription factor activity
M2J07_12480	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_12490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M2J07_12495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M2J07_12500	COG0833	amino acid
M2J07_12530	COG1192	Involved in chromosome partitioning
M2J07_12535	COG0628	permease
M2J07_12545	COG1289	transmembrane transporter activity
M2J07_12560	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2J07_12565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M2J07_12575	COG0277	FAD linked oxidase domain protein
M2J07_12580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M2J07_12615	COG1061	Type III restriction enzyme res subunit
M2J07_12625	COG1192	Involved in chromosome partitioning
M2J07_12630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M2J07_12640	COG1061	Type III restriction enzyme res subunit
M2J07_12660	COG1061	Type III restriction enzyme res subunit
M2J07_12670	COG1192	Involved in chromosome partitioning
M2J07_12675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M2J07_12685	COG1061	Type III restriction enzyme res subunit
M2J07_12700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M2J07_12705	COG5380	lipid catabolic process
M2J07_12725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M2J07_12775	COG0194	GDP metabolic process
M2J07_12790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M2J07_12810	COG3307	-O-antigen
M2J07_12815	COG4969	Belongs to the N-Me-Phe pilin family
M2J07_12825	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M2J07_12830	COG1704	LemA family
M2J07_12840	COG0493	'glutamate synthase
M2J07_12845	COG0067	glutamate synthase
M2J07_12845	COG0069	glutamate synthase activity
M2J07_12845	COG0070	glutamate synthase
M2J07_12895	COG2226	methyltransferase
M2J07_12910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M2J07_12915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M2J07_12960	COG0833	amino acid
M2J07_13045	COG0488	(ABC) transporter
M2J07_13050	COG2873	o-acetylhomoserine
M2J07_13055	COG4221	oxidoreductase activity
M2J07_13060	COG0659	secondary active sulfate transmembrane transporter activity
M2J07_13085	COG0427	acetyl-CoA hydrolase
M2J07_13115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M2J07_13145	COG2329	Antibiotic biosynthesis monooxygenase
M2J07_13160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M2J07_13225	COG2249	NAD(P)H dehydrogenase (quinone) activity
M2J07_13230	COG1733	regulation of RNA biosynthetic process
M2J07_13265	COG0667	Aldo Keto reductase
M2J07_13290	COG0583	DNA-binding transcription factor activity
M2J07_13295	COG2814	Major facilitator Superfamily
M2J07_13325	COG1335	isochorismatase
M2J07_13335	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_13340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M2J07_13350	COG1113	amino acid transport
M2J07_13360	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M2J07_13375	COG2814	Major facilitator Superfamily
M2J07_13385	COG0351	phosphomethylpyrimidine kinase
M2J07_13385	COG0352	thiamine-phosphate diphosphorylase activity
M2J07_13385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M2J07_13405	COG1309	transcriptional regulator
M2J07_13410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M2J07_13430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M2J07_13440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M2J07_13445	COG3162	membrane
M2J07_13450	COG2198	Histidine kinase
M2J07_13450	COG2205	protein histidine kinase activity
M2J07_13450	COG0784	Response regulator, receiver
M2J07_13475	COG3328	transposase activity
M2J07_13480	COG1522	sequence-specific DNA binding
M2J07_13485	COG1335	isochorismatase
M2J07_13490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M2J07_13500	COG0668	transmembrane transport
M2J07_13505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M2J07_13510	COG1519	Transferase
M2J07_13515	COG1902	pentaerythritol trinitrate reductase activity
M2J07_13535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M2J07_13560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M2J07_13560	COG0426	domain, Protein
M2J07_13565	COG4774	siderophore transport
M2J07_13570	COG2119	membrane
M2J07_13580	COG0508	dehydrogenase complex catalyzes the overall conversion of
M2J07_13590	COG4942	peptidase
M2J07_13605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M2J07_13615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M2J07_13635	COG0189	ligase activity
M2J07_13655	COG0708	Exodeoxyribonuclease III
M2J07_13660	COG1393	Belongs to the ArsC family
M2J07_13675	COG3706	GGDEF domain
M2J07_13710	COG2351	hydroxyisourate hydrolase activity
M2J07_13715	COG2233	PERMEase
M2J07_13725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2J07_13735	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M2J07_13740	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_13750	COG3150	esterase
M2J07_13780	COG2918	glutathione biosynthetic process
M2J07_13795	COG2733	membrane
M2J07_13800	COG0436	Aminotransferase
M2J07_13805	COG0534	Mate efflux family protein
M2J07_13905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M2J07_13910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M2J07_13920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M2J07_13925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M2J07_13945	COG0010	Belongs to the arginase family
M2J07_13975	COG2188	Transcriptional regulator
M2J07_13985	COG0523	cobalamin synthesis protein
M2J07_13995	COG1113	amino acid transport
M2J07_14005	COG0625	glutathione transferase activity
M2J07_14025	COG1683	Conserved Protein
M2J07_14030	COG0534	Mate efflux family protein
M2J07_14035	COG0385	Bile acid
M2J07_14040	COG1335	isochorismatase
M2J07_14045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M2J07_14065	COG2116	formate transmembrane transporter activity
M2J07_14070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M2J07_14075	COG2133	pyrroloquinoline quinone binding
M2J07_14080	COG2983	Belongs to the UPF0260 family
M2J07_14100	COG1194	a g-specific adenine glycosylase
M2J07_14115	COG2818	Glycosylase
M2J07_14120	COG1064	alcohol dehydrogenase
M2J07_14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2J07_14140	COG0583	DNA-binding transcription factor activity
M2J07_14145	COG0656	L-ascorbic acid biosynthetic process
M2J07_14150	COG2814	Major facilitator Superfamily
M2J07_14185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_14200	COG2233	PERMEase
M2J07_14240	COG0733	neurotransmitter:sodium symporter activity
M2J07_14280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M2J07_14285	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M2J07_14290	COG0596	Alpha beta hydrolase
M2J07_14315	COG0488	(ABC) transporter
M2J07_14320	COG0586	Pfam SNARE associated Golgi protein
M2J07_14330	COG0187	DNA topoisomerase II activity
M2J07_14340	COG0592	DNA-directed DNA polymerase activity
M2J07_14365	COG0706	membrane insertase activity
M2J07_14380	COG1230	cation diffusion facilitator family transporter
M2J07_14385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M2J07_14400	COG0402	S-adenosylhomocysteine deaminase activity
M2J07_14410	COG0754	glutathionylspermidine amidase activity
M2J07_14420	COG0861	Integral membrane protein TerC family
M2J07_14425	COG0671	phosphoesterase, PA-phosphatase related
M2J07_14435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M2J07_14450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M2J07_14455	COG2951	lytic endotransglycosylase activity
M2J07_14485	COG0583	DNA-binding transcription factor activity
M2J07_14505	COG0657	acetylesterase activity
M2J07_14510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M2J07_14550	COG1047	Peptidyl-prolyl cis-trans
M2J07_14560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M2J07_14565	COG0196	riboflavin kinase activity
M2J07_14575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M2J07_14580	COG1309	transcriptional regulator
M2J07_14585	COG1116	anion transmembrane transporter activity
M2J07_14590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M2J07_14595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M2J07_14600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2J07_14605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M2J07_14625	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_14630	COG0546	phosphoglycolate phosphatase activity
M2J07_14685	COG3023	N-Acetylmuramoyl-L-alanine amidase
M2J07_14690	COG0728	peptidoglycan biosynthetic process
M2J07_14715	COG1596	polysaccharide export
M2J07_14720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M2J07_14730	COG5039	Polysaccharide pyruvyl transferase
M2J07_14735	COG1216	Glycosyl transferase, family 2
M2J07_14755	COG0438	transferase activity, transferring glycosyl groups
M2J07_14760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M2J07_14770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M2J07_14780	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M2J07_14795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M2J07_14800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M2J07_14810	COG2186	Transcriptional regulator
M2J07_14820	COG0277	FAD linked oxidase domain protein
M2J07_14825	COG1448	Aminotransferase
M2J07_14835	COG1802	Transcriptional regulator
M2J07_14850	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M2J07_14910	COG0564	pseudouridine synthase activity
M2J07_14950	COG0251	oxidation-reduction process
M2J07_14955	COG1113	amino acid transport
M2J07_14960	COG1113	amino acid transport
M2J07_14980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M2J07_14985	COG1960	acyl-CoA dehydrogenase activity
M2J07_14990	COG1024	Enoyl-CoA hydratase
M2J07_14995	COG1024	Enoyl-CoA hydratase
M2J07_15000	COG0477	Major facilitator Superfamily
M2J07_15005	COG3916	Acyl-homoserine-lactone synthase
M2J07_15015	COG2197	response regulator
M2J07_15025	COG1960	acyl-CoA dehydrogenase activity
M2J07_15030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M2J07_15030	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M2J07_15030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2J07_15030	COG3321	synthase
M2J07_15050	COG2267	carboxylic ester hydrolase activity
M2J07_15070	COG0271	Belongs to the BolA IbaG family
M2J07_15080	COG1192	Involved in chromosome partitioning
M2J07_15095	COG0586	Pfam SNARE associated Golgi protein
M2J07_15100	COG2259	Doxx family
M2J07_15105	COG4399	Belongs to the UPF0754 family
M2J07_15110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M2J07_15110	COG0519	Catalyzes the synthesis of GMP from XMP
M2J07_15155	COG0281	malic enzyme
M2J07_15165	COG2837	iron assimilation
M2J07_15170	COG1280	lysine exporter protein (LysE YggA)
M2J07_15175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M2J07_15180	COG1121	(ABC) transporter
M2J07_15245	COG0386	Belongs to the glutathione peroxidase family
M2J07_15260	COG1309	transcriptional regulator
M2J07_15265	COG0697	spore germination
M2J07_15275	COG0758	DNA mediated transformation
M2J07_15345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M2J07_15355	COG0655	NAD(P)H dehydrogenase (quinone) activity
M2J07_15395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M2J07_15415	COG1253	flavin adenine dinucleotide binding
M2J07_15425	COG2860	membrane
M2J07_15430	COG0477	Major facilitator Superfamily
M2J07_15440	COG0318	PFAM AMP-dependent synthetase and ligase
M2J07_15455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M2J07_15475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M2J07_15485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M2J07_15520	COG0589	response to stress
M2J07_15525	COG0659	secondary active sulfate transmembrane transporter activity
M2J07_15585	COG0347	Belongs to the P(II) protein family
M2J07_15590	COG0004	ammonium transporteR
M2J07_15600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M2J07_15600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M2J07_15640	COG0795	lipopolysaccharide-transporting ATPase activity
M2J07_15645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M2J07_15650	COG0793	Belongs to the peptidase S41A family
M2J07_15665	COG2197	response regulator
M2J07_15675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M2J07_15685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M2J07_15690	COG4974	Belongs to the 'phage' integrase family
M2J07_15715	COG0772	Belongs to the SEDS family
M2J07_15720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M2J07_15725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M2J07_15730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M2J07_15755	COG0697	spore germination
M2J07_15760	COG1538	Outer membrane efflux protein
M2J07_15780	COG3275	phosphorelay sensor kinase activity
M2J07_15790	COG0181	hydroxymethylbilane synthase activity
M2J07_15835	COG1716	ATPase activity
M2J07_15840	COG0546	phosphoglycolate phosphatase activity
M2J07_15935	COG0596	Alpha beta hydrolase
M2J07_15940	COG2056	Na+-H+ antiporter family
M2J07_15955	COG0326	Molecular chaperone. Has ATPase activity
M2J07_15970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M2J07_16035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M2J07_16040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M2J07_16040	COG2169	Transcriptional regulator
M2J07_16070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M2J07_16080	COG0497	DNA recombination
M2J07_16095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M2J07_16105	COG0237	dephospho-CoA kinase activity
M2J07_16110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M2J07_16160	COG0195	Participates in both transcription termination and antitermination
M2J07_16175	COG1320	monovalent cation:proton antiporter activity
M2J07_16180	COG2212	antiporter activity
M2J07_16185	COG1863	multisubunit Na H antiporter MnhE subunit
M2J07_16190	COG0651	ATP synthesis coupled electron transport
M2J07_16195	COG1006	Multisubunit Na H antiporter MnhC subunit
M2J07_16200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M2J07_16200	COG2111	Na H antiporter
M2J07_16215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M2J07_16220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M2J07_16235	COG2226	methyltransferase
M2J07_16255	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M2J07_16260	COG1074	ATP-dependent DNA helicase activity
M2J07_16265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M2J07_16270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M2J07_16285	COG0598	Magnesium transport protein CorA
M2J07_16290	COG0789	Transcriptional regulator
M2J07_16295	COG0484	heat shock protein binding
M2J07_16305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M2J07_16310	COG0475	glutathione-regulated potassium exporter activity
M2J07_16310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M2J07_16315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M2J07_16335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2J07_16345	COG4535	Mg2 and Co2 transporter CorC
M2J07_16350	COG0425	Belongs to the sulfur carrier protein TusA family
M2J07_16355	COG0644	oxidoreductase
M2J07_16355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M2J07_16365	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M2J07_16380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M2J07_16385	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M2J07_16425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M2J07_16440	COG0534	Mate efflux family protein
M2J07_16450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M2J07_16455	COG4221	oxidoreductase activity
M2J07_16460	COG0583	DNA-binding transcription factor activity
M2J07_16475	COG0318	PFAM AMP-dependent synthetase and ligase
M2J07_16480	COG1530	ribonuclease E activity
M2J07_16490	COG0546	phosphoglycolate phosphatase activity
M2J07_16495	COG2378	regulation of single-species biofilm formation
M2J07_16500	COG0625	glutathione transferase activity
M2J07_16510	COG0583	DNA-binding transcription factor activity
M2J07_16575	COG0473	3-isopropylmalate dehydrogenase activity
M2J07_16630	COG1301	dicarboxylic acid transport
M2J07_16640	COG1560	Kdo2-lipid A biosynthetic process
M2J07_16645	COG1280	lysine exporter protein (LysE YggA)
M2J07_16650	COG0488	(ABC) transporter
M2J07_16655	COG2900	Belongs to the SlyX family
M2J07_16665	COG1733	regulation of RNA biosynthetic process
M2J07_16690	COG0210	DNA helicase
M2J07_16695	COG0724	RNA recognition motif
M2J07_16715	COG4651	solute:proton antiporter activity
M2J07_16715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M2J07_16740	COG0788	formyltetrahydrofolate deformylase activity
M2J07_16840	COG2813	Specifically methylates the guanine in position
M2J07_16840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M2J07_16850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M2J07_16860	COG4774	siderophore transport
M2J07_16870	COG0740	serine-type endopeptidase activity
M2J07_16890	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M2J07_16890	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M2J07_16895	COG0280	phosphate acetyltransferase
M2J07_16895	COG0857	belongs to the CobB CobQ family
M2J07_16900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M2J07_16910	COG0800	Aldolase
M2J07_16920	COG3265	gluconokinase activity
M2J07_16925	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_16935	COG2267	carboxylic ester hydrolase activity
M2J07_16950	COG0793	Belongs to the peptidase S41A family
M2J07_16985	COG1426	Protein conserved in bacteria
M2J07_17030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M2J07_17040	COG0318	PFAM AMP-dependent synthetase and ligase
M2J07_17055	COG2986	histidine ammonia-lyase
M2J07_17095	COG1028	Short-chain dehydrogenase reductase Sdr
M2J07_17100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M2J07_17120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M2J07_17130	COG1162	GTPase activity
M2J07_17135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M2J07_17150	COG1538	Outer membrane efflux protein
M2J07_17155	COG1136	(ABC) transporter
M2J07_17155	COG0577	efflux transmembrane transporter activity
M2J07_17160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M2J07_17185	COG0028	Belongs to the TPP enzyme family
M2J07_17190	COG0440	acetolactate synthase activity
M2J07_17225	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M2J07_17240	COG0084	hydrolase, TatD family'
M2J07_17255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M2J07_17265	COG0583	DNA-binding transcription factor activity
M2J07_17275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M2J07_17280	COG2814	Major facilitator Superfamily
M2J07_17290	COG0697	spore germination
M2J07_17320	COG3622	Belongs to the hyi family
M2J07_17325	COG2084	Dehydrogenase
M2J07_17330	COG1024	Enoyl-CoA hydratase
M2J07_17335	COG2205	protein histidine kinase activity
M2J07_17335	COG0784	Response regulator, receiver
M2J07_17335	COG5002	protein histidine kinase activity
M2J07_17355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M2J07_17365	COG3956	TIGRFAM MazG family protein
M2J07_17370	COG1555	photosystem II stabilization
M2J07_17375	COG0617	tRNA 3'-terminal CCA addition
M2J07_17380	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M2J07_17400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M2J07_17405	COG3028	Belongs to the UPF0307 family
M2J07_17410	COG0318	PFAM AMP-dependent synthetase and ligase
M2J07_17425	COG0625	glutathione transferase activity
M2J07_17430	COG1238	metal cluster binding
M2J07_17475	COG0072	phenylalanine-tRNA ligase activity
M2J07_17505	COG0248	Ppx GppA phosphatase
M2J07_17515	COG0037	tRNA processing
M2J07_17565	COG1764	response to oxidative stress
M2J07_17570	COG1846	Transcriptional regulator
M2J07_17580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M2J07_17640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M2J07_17645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M2J07_17650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M2J07_17660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M2J07_17710	COG1214	PFAM Peptidase M22, glycoprotease
M2J07_17735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M2J07_17740	COG0561	phosphatase activity
M2J07_17750	COG2132	Multicopper oxidase
M2J07_17755	COG3667	copper resistance
M2J07_17770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M2J07_17775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M2J07_17780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M2J07_17810	COG1063	alcohol dehydrogenase
M2J07_17815	COG0583	DNA-binding transcription factor activity
M2J07_17820	COG1960	acyl-CoA dehydrogenase activity
M2J07_17825	COG2814	Major facilitator Superfamily
M2J07_17830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M2J07_17840	COG1053	succinate dehydrogenase
M2J07_17845	COG0583	DNA-binding transcription factor activity
M2J07_17860	COG0583	DNA-binding transcription factor activity
M2J07_17890	COG0583	DNA-binding transcription factor activity
M2J07_17905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M2J07_17930	COG0384	phenazine biosynthesis protein PhzF
M2J07_17955	COG4993	Dehydrogenase
M2J07_18025	COG2205	protein histidine kinase activity
M2J07_18035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M2J07_18055	COG0745	RESPONSE REGULATOR receiver
M2J07_18095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M2J07_18125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M2J07_18130	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M2J07_18150	COG0583	DNA-binding transcription factor activity
M2J07_18170	COG0668	transmembrane transport
M2J07_18180	COG2081	HI0933 family
M2J07_18185	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M2J07_18215	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2J07_18215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M2J07_18225	COG0489	protein tyrosine kinase activity
M2J07_18275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M2J07_18285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M2J07_18300	COG0730	response to heat
M2J07_18310	COG1196	nuclear chromosome segregation
M2J07_18330	COG2223	nitrite transmembrane transporter activity
M2J07_18335	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M2J07_18340	COG1877	trehalose-phosphatase activity
M2J07_18345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M2J07_18345	COG2226	methyltransferase
M2J07_18345	COG0596	Alpha beta hydrolase
M2J07_18360	COG4106	trans-aconitate 2-methyltransferase activity
M2J07_18375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M2J07_18380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M2J07_18385	COG0009	L-threonylcarbamoyladenylate synthase
M2J07_18390	COG3101	peptidyl-lysine hydroxylation
M2J07_18395	COG1399	metal-binding, possibly nucleic acid-binding protein
M2J07_18420	COG1652	LysM domain
M2J07_18425	COG0351	phosphomethylpyrimidine kinase
M2J07_18425	COG0352	thiamine-phosphate diphosphorylase activity
M2J07_18425	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M2J07_18435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M2J07_18465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M2J07_18490	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M2J07_18505	COG0358	DNA primase activity
M2J07_18515	COG0564	pseudouridine synthase activity
M2J07_18540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M2J07_18560	COG0583	DNA-binding transcription factor activity
M2J07_18565	COG0473	3-isopropylmalate dehydrogenase activity
M2J07_18575	COG0657	acetylesterase activity
M2J07_18585	COG1012	belongs to the aldehyde dehydrogenase family
M2J07_18605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M2J07_18605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M2J07_18620	COG1981	membrane
M2J07_18665	COG0456	acetyltransferase
M2J07_18675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M2J07_18680	COG0492	ferredoxin-NADP+ reductase activity
M2J07_18685	COG1674	ftsk spoiiie
M2J07_18685	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M2J07_18690	COG1280	lysine exporter protein (LysE YggA)
M2J07_18710	COG2894	cell division
M2J07_18725	COG0204	Acyl-transferase
M2J07_18730	COG2885	chlorophyll binding
M2J07_18735	COG0210	DNA helicase
M2J07_18745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M2J07_18760	COG0121	glutamine amidotransferase
M2J07_18780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M2J07_18785	COG0735	belongs to the Fur family
M2J07_18810	COG0420	3'-5' exonuclease activity