locus-tag	class	description
LRX85_00015	COG4584	PFAM Integrase catalytic
LRX85_00025	COG1484	DNA-dependent DNA replication
LRX85_00045	COG2826	transposase and inactivated derivatives, IS30 family
LRX85_00065	COG0673	inositol 2-dehydrogenase activity
LRX85_00070	COG1324	tolerance protein
LRX85_00080	COG1484	DNA-dependent DNA replication
LRX85_00115	COG2826	transposase and inactivated derivatives, IS30 family
LRX85_00120	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LRX85_00130	COG2826	transposase and inactivated derivatives, IS30 family
LRX85_00180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LRX85_00190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LRX85_00195	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LRX85_00240	COG0753	catalase activity
LRX85_00290	COG0534	Mate efflux family protein
LRX85_00295	COG0436	Aminotransferase
LRX85_00300	COG2733	membrane
LRX85_00315	COG2918	glutathione biosynthetic process
LRX85_00400	COG3150	esterase
LRX85_00410	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_00415	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LRX85_00425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRX85_00435	COG2233	PERMEase
LRX85_00440	COG2351	hydroxyisourate hydrolase activity
LRX85_00475	COG3706	GGDEF domain
LRX85_00490	COG1393	Belongs to the ArsC family
LRX85_00495	COG0708	Exodeoxyribonuclease III
LRX85_00520	COG0189	ligase activity
LRX85_00540	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LRX85_00550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LRX85_00565	COG4942	peptidase
LRX85_00575	COG0508	dehydrogenase complex catalyzes the overall conversion of
LRX85_00585	COG2119	membrane
LRX85_00595	COG0426	domain, Protein
LRX85_00595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRX85_00620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LRX85_00640	COG1902	pentaerythritol trinitrate reductase activity
LRX85_00645	COG1519	Transferase
LRX85_00650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LRX85_00655	COG0668	transmembrane transport
LRX85_00670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LRX85_00675	COG1335	isochorismatase
LRX85_00680	COG1522	sequence-specific DNA binding
LRX85_00705	COG0784	Response regulator, receiver
LRX85_00705	COG2198	Histidine kinase
LRX85_00705	COG2205	protein histidine kinase activity
LRX85_00710	COG3162	membrane
LRX85_00715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LRX85_00725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRX85_00740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LRX85_00745	COG1309	transcriptional regulator
LRX85_00765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LRX85_00765	COG0351	phosphomethylpyrimidine kinase
LRX85_00765	COG0352	thiamine-phosphate diphosphorylase activity
LRX85_00775	COG2814	Major facilitator Superfamily
LRX85_00790	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LRX85_00800	COG1113	amino acid transport
LRX85_00810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LRX85_00815	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_00825	COG1335	isochorismatase
LRX85_00875	COG2814	Major facilitator Superfamily
LRX85_00880	COG0583	DNA-binding transcription factor activity
LRX85_00900	COG0667	Aldo Keto reductase
LRX85_00935	COG1733	regulation of RNA biosynthetic process
LRX85_00940	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRX85_01010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LRX85_01025	COG2329	Antibiotic biosynthesis monooxygenase
LRX85_01040	COG1132	(ABC) transporter
LRX85_01060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LRX85_01090	COG0427	acetyl-CoA hydrolase
LRX85_01115	COG0659	secondary active sulfate transmembrane transporter activity
LRX85_01120	COG4221	oxidoreductase activity
LRX85_01125	COG2873	o-acetylhomoserine
LRX85_01130	COG0488	(ABC) transporter
LRX85_01215	COG0833	amino acid
LRX85_01260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LRX85_01265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LRX85_01280	COG2226	methyltransferase
LRX85_01330	COG0069	glutamate synthase activity
LRX85_01330	COG0070	glutamate synthase
LRX85_01330	COG0067	glutamate synthase
LRX85_01335	COG0493	'glutamate synthase
LRX85_01345	COG1704	LemA family
LRX85_01350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LRX85_01370	COG3307	-O-antigen
LRX85_01390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LRX85_01405	COG0194	GDP metabolic process
LRX85_01455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LRX85_01475	COG5380	lipid catabolic process
LRX85_01480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LRX85_01505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LRX85_01510	COG0277	FAD linked oxidase domain protein
LRX85_01520	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LRX85_01525	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRX85_01540	COG1289	transmembrane transporter activity
LRX85_01545	COG2032	superoxide dismutase activity
LRX85_01550	COG0628	permease
LRX85_01555	COG1192	Involved in chromosome partitioning
LRX85_01585	COG0833	amino acid
LRX85_01590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LRX85_01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LRX85_01605	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_01645	COG0583	DNA-binding transcription factor activity
LRX85_01700	COG0517	IMP dehydrogenase activity
LRX85_01705	COG1983	PspC domain protein
LRX85_01715	COG1960	acyl-CoA dehydrogenase activity
LRX85_01730	COG0408	coproporphyrinogen oxidase activity
LRX85_01750	COG0513	Belongs to the DEAD box helicase family
LRX85_01760	COG1127	ABC transporter
LRX85_01765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LRX85_01775	COG2854	intermembrane phospholipid transfer
LRX85_01785	COG0598	Magnesium transport protein CorA
LRX85_01795	COG0494	nUDIX hydrolase
LRX85_01800	COG1040	competence protein
LRX85_01805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LRX85_01825	COG1946	Acyl-CoA thioesterase
LRX85_01830	COG1301	dicarboxylic acid transport
LRX85_01845	COG1959	2 iron, 2 sulfur cluster binding
LRX85_01850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRX85_01850	COG1017	nitric oxide dioxygenase activity
LRX85_01860	COG0433	COG0433 Predicted ATPase
LRX85_01865	COG0626	cystathionine gamma-synthase activity
LRX85_02020	COG1960	acyl-CoA dehydrogenase activity
LRX85_02025	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LRX85_02055	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LRX85_02060	COG0339	signal peptide processing
LRX85_02065	COG0557	exoribonuclease II activity
LRX85_02110	COG0179	Fumarylacetoacetate (FAA) hydrolase
LRX85_02115	COG2169	Transcriptional regulator
LRX85_02120	COG0697	spore germination
LRX85_02125	COG1295	ribonuclease BN
LRX85_02160	COG1702	phosphate starvation-inducible protein PhoH
LRX85_02170	COG0741	lytic transglycosylase activity
LRX85_02170	COG0739	heme binding
LRX85_02170	COG1196	nuclear chromosome segregation
LRX85_02200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LRX85_02205	COG1183	phosphatidylcholine synthase activity
LRX85_02250	COG1960	acyl-CoA dehydrogenase activity
LRX85_02255	COG1309	transcriptional regulator
LRX85_02270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LRX85_02275	COG1960	acyl-CoA dehydrogenase activity
LRX85_02295	COG2969	positive regulation of protein catabolic process
LRX85_02305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LRX85_02315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LRX85_02320	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LRX85_02325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LRX85_02345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LRX85_02355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LRX85_02360	COG1408	metallophosphoesterase
LRX85_02370	COG2199	diguanylate cyclase activity
LRX85_02405	COG3328	transposase activity
LRX85_02435	COG1607	acyl-coa hydrolase
LRX85_02465	COG2350	Protein conserved in bacteria
LRX85_02475	COG0613	PHP domain protein
LRX85_02480	COG3781	membrane
LRX85_02490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LRX85_02500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LRX85_02510	COG1862	Preprotein translocase
LRX85_02550	COG2205	protein histidine kinase activity
LRX85_02555	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LRX85_02570	COG0726	polysaccharide deacetylase
LRX85_02575	COG0438	transferase activity, transferring glycosyl groups
LRX85_02585	COG0438	transferase activity, transferring glycosyl groups
LRX85_02610	COG1442	glycosyl transferase family 8
LRX85_02665	COG1960	acyl-CoA dehydrogenase activity
LRX85_02670	COG1960	acyl-CoA dehydrogenase activity
LRX85_02680	COG2205	protein histidine kinase activity
LRX85_02685	COG0745	RESPONSE REGULATOR receiver
LRX85_02690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LRX85_02705	COG0584	glycerophosphoryl diester phosphodiesterase
LRX85_02710	COG2096	Adenosyltransferase
LRX85_02760	COG0285	dihydrofolate synthase activity
LRX85_02780	COG0450	alkyl hydroperoxide reductase
LRX85_02795	COG0477	Major facilitator Superfamily
LRX85_02800	COG1272	protein, Hemolysin III
LRX85_02830	COG0183	Belongs to the thiolase family
LRX85_02835	COG2207	Transcriptional regulator
LRX85_02855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRX85_02875	COG0183	Belongs to the thiolase family
LRX85_02885	COG2885	chlorophyll binding
LRX85_02885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LRX85_02895	COG1690	Belongs to the RtcB family
LRX85_02900	COG0833	amino acid
LRX85_02910	COG2233	PERMEase
LRX85_02915	COG1217	gtp-binding protein TYPA
LRX85_02940	COG2094	Belongs to the DNA glycosylase MPG family
LRX85_02950	COG1902	pentaerythritol trinitrate reductase activity
LRX85_02965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LRX85_02970	COG0354	folic acid binding
LRX85_02980	COG3189	MarR family transcriptional regulator
LRX85_02985	COG2824	Alkylphosphonate utilization operon protein PhnA
LRX85_02990	COG3422	double-strand break repair
LRX85_03010	COG1002	Type II restriction enzyme, methylase subunits
LRX85_03015	COG1061	Type III restriction enzyme res subunit
LRX85_03065	COG0840	transmembrane signaling receptor activity
LRX85_03085	COG5510	response to toxic substance
LRX85_03095	COG2832	Protein of unknown function (DUF454)
LRX85_03100	COG1376	ErfK ybiS ycfS ynhG family protein
LRX85_03140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LRX85_03150	COG1289	transmembrane transporter activity
LRX85_03155	COG2814	Major facilitator Superfamily
LRX85_03175	COG1115	amino acid carrier protein
LRX85_03180	COG1752	Esterase of the alpha-beta hydrolase superfamily
LRX85_03185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LRX85_03190	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LRX85_03215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LRX85_03225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LRX85_03230	COG1077	Cell shape determining protein MreB Mrl
LRX85_03235	COG1792	Involved in formation and maintenance of cell shape
LRX85_03240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LRX85_03245	COG0424	maF-like protein
LRX85_03250	COG1530	ribonuclease E activity
LRX85_03260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRX85_03270	COG0560	Phosphoserine phosphatase
LRX85_03280	COG2249	NAD(P)H dehydrogenase (quinone) activity
LRX85_03305	COG2207	Transcriptional regulator
LRX85_03325	COG1113	amino acid transport
LRX85_03330	COG2828	Protein conserved in bacteria
LRX85_03335	COG0142	geranyltranstransferase activity
LRX85_03340	COG2315	Protein conserved in bacteria
LRX85_03355	COG1752	Esterase of the alpha-beta hydrolase superfamily
LRX85_03375	COG2194	sulfuric ester hydrolase activity
LRX85_03380	COG0745	RESPONSE REGULATOR receiver
LRX85_03385	COG0642	Histidine kinase
LRX85_03395	COG0004	ammonium transporteR
LRX85_03400	COG0583	DNA-binding transcription factor activity
LRX85_03420	COG0525	valine-tRNA ligase activity
LRX85_03430	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_03440	COG0393	Putative heavy-metal-binding
LRX85_03445	COG0393	Putative heavy-metal-binding
LRX85_03450	COG1538	Outer membrane efflux protein
LRX85_03460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_03465	COG0671	phosphoesterase, PA-phosphatase related
LRX85_03495	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LRX85_03510	COG1648	precorrin-2 dehydrogenase activity
LRX85_03510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LRX85_03515	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LRX85_03530	COG0531	amino acid
LRX85_03545	COG0321	lipoyl(octanoyl) transferase activity
LRX85_03550	COG2921	Belongs to the UPF0250 family
LRX85_03585	COG2009	succinate dehydrogenase
LRX85_03590	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LRX85_03595	COG1053	succinate dehydrogenase
LRX85_03600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LRX85_03625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRX85_03645	COG2354	Protein conserved in bacteria
LRX85_03650	COG2321	neutral zinc metallopeptidase
LRX85_03670	COG2843	Capsule synthesis protein
LRX85_03685	COG0589	response to stress
LRX85_03705	COG0505	Belongs to the CarA family
LRX85_03730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LRX85_03735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LRX85_03785	COG0477	Major facilitator Superfamily
LRX85_03790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LRX85_03805	COG1597	lipid kinase activity
LRX85_03810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LRX85_03830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRX85_03835	COG0584	glycerophosphoryl diester phosphodiesterase
LRX85_03855	COG0741	lytic transglycosylase activity
LRX85_03875	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LRX85_03890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRX85_03900	COG3811	Belongs to the UPF0386 family
LRX85_03935	COG0778	Nitroreductase
LRX85_03950	COG1929	Belongs to the glycerate kinase type-1 family
LRX85_03955	COG0243	molybdopterin cofactor binding
LRX85_03960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LRX85_03975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LRX85_03990	COG1113	amino acid transport
LRX85_04000	COG0019	diaminopimelate decarboxylase activity
LRX85_04010	COG1280	lysine exporter protein (LysE YggA)
LRX85_04015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LRX85_04045	COG0463	Glycosyl transferase, family 2
LRX85_04065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_04100	COG4591	ABC-type transport system involved in lipoprotein release permease component
LRX85_04105	COG1136	(ABC) transporter
LRX85_04110	COG0658	competence protein
LRX85_04110	COG2333	competence protein COMEC
LRX85_04120	COG0616	signal peptide processing
LRX85_04120	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LRX85_04125	COG0596	Alpha beta hydrolase
LRX85_04130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LRX85_04140	COG0628	permease
LRX85_04165	COG2826	transposase and inactivated derivatives, IS30 family
LRX85_04195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LRX85_04215	COG0823	Involved in the tonB-independent uptake of proteins
LRX85_04235	COG0824	Thioesterase
LRX85_04240	COG1473	amidohydrolase
LRX85_04265	COG0047	phosphoribosylformylglycinamidine synthase activity
LRX85_04265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LRX85_04270	COG2814	Major facilitator Superfamily
LRX85_04280	COG1024	Enoyl-CoA hydratase
LRX85_04285	COG1051	belongs to the nudix hydrolase family
LRX85_04285	COG1056	cytidyltransferase-related domain
LRX85_04295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LRX85_04310	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LRX85_04325	COG4625	pathogenesis
LRX85_04330	COG0583	DNA-binding transcription factor activity
LRX85_04335	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LRX85_04340	COG4208	sulfate ABC transporter
LRX85_04345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LRX85_04355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LRX85_04360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LRX85_04365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LRX85_04385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LRX85_04400	COG0681	Belongs to the peptidase S26 family
LRX85_04415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LRX85_04425	COG1381	Involved in DNA repair and RecF pathway recombination
LRX85_04430	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LRX85_04440	COG4221	oxidoreductase activity
LRX85_04470	COG0436	Aminotransferase
LRX85_04490	COG0556	nucleotide-excision repair
LRX85_04545	COG2070	2-Nitropropane dioxygenase
LRX85_04575	COG1215	transferase activity, transferring glycosyl groups
LRX85_04590	COG0415	Belongs to the DNA photolyase family
LRX85_04600	COG1252	NADH dehydrogenase
LRX85_04605	COG1686	Belongs to the peptidase S11 family
LRX85_04620	COG1187	pseudouridine synthase activity
LRX85_04645	COG0477	Major facilitator Superfamily
LRX85_04650	COG0583	DNA-binding transcription factor activity
LRX85_04655	COG1823	symporter activity
LRX85_04665	COG0612	Peptidase, M16
LRX85_04690	COG0352	thiamine-phosphate diphosphorylase activity
LRX85_04725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRX85_04740	COG1309	transcriptional regulator
LRX85_04755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LRX85_04760	COG0076	glutamate decarboxylase activity
LRX85_04770	COG1522	sequence-specific DNA binding
LRX85_04775	COG3961	Belongs to the TPP enzyme family
LRX85_04780	COG1113	amino acid transport
LRX85_04785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LRX85_04790	COG0573	inorganic phosphate transmembrane transporter activity
LRX85_04800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LRX85_04805	COG0616	signal peptide processing
LRX85_04840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LRX85_04845	COG1686	Belongs to the peptidase S11 family
LRX85_04870	COG0583	DNA-binding transcription factor activity
LRX85_04875	COG1067	ATP-dependent peptidase activity
LRX85_04900	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LRX85_04920	COG1966	Carbon starvation protein
LRX85_04925	COG2879	small protein
LRX85_04940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LRX85_04950	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LRX85_04955	COG1396	sequence-specific DNA binding
LRX85_04980	COG1741	Belongs to the pirin family
LRX85_04990	COG2964	Protein conserved in bacteria
LRX85_05005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRX85_05010	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LRX85_05015	COG4605	iron ion homeostasis
LRX85_05020	COG4604	ABC transporter, ATP-binding protein
LRX85_05025	COG4607	ABC-type enterochelin transport system periplasmic component
LRX85_05030	COG4774	siderophore transport
LRX85_05040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LRX85_05045	COG1021	2,3-dihydroxybenzoate-AMP ligase
LRX85_05050	COG3433	isochorismatase activity
LRX85_05050	COG1535	isochorismatase
LRX85_05065	COG1132	(ABC) transporter
LRX85_05070	COG1132	(ABC) transporter
LRX85_05075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LRX85_05085	COG1169	isochorismate synthase
LRX85_05100	COG3739	integral membrane protein
LRX85_05120	COG0302	gtp cyclohydrolase
LRX85_05130	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LRX85_05165	COG0512	Glutamine amidotransferase of anthranilate synthase
LRX85_05180	COG0174	glutamine synthetase
LRX85_05190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LRX85_05225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LRX85_05230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LRX85_05235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LRX85_05255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LRX85_05260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LRX85_05265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LRX85_05280	COG1960	acyl-CoA dehydrogenase activity
LRX85_05285	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LRX85_05290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRX85_05300	COG2223	nitrite transmembrane transporter activity
LRX85_05310	COG0024	Methionine aminopeptidase
LRX85_05315	COG0052	Belongs to the universal ribosomal protein uS2 family
LRX85_05330	COG2207	Transcriptional regulator
LRX85_05355	COG2951	lytic endotransglycosylase activity
LRX85_05360	COG0772	Belongs to the SEDS family
LRX85_05375	COG0842	Transport permease protein
LRX85_05380	COG1131	(ABC) transporter
LRX85_05390	COG1002	Type II restriction enzyme, methylase subunits
LRX85_05395	COG1061	Type III restriction enzyme res subunit
LRX85_05415	COG0582	viral genome integration into host DNA
LRX85_05450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LRX85_05760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_05775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LRX85_05780	COG0826	peptidase U32
LRX85_05785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRX85_05800	COG1720	tRNA m6t6A37 methyltransferase activity
LRX85_05810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LRX85_05825	COG0642	Histidine kinase
LRX85_05835	COG0494	nUDIX hydrolase
LRX85_05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LRX85_05850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LRX85_05855	COG3139	Protein of unknown function (DUF1315)
LRX85_05865	COG1301	dicarboxylic acid transport
LRX85_05870	COG1960	acyl-CoA dehydrogenase activity
LRX85_05875	COG2819	hydrolase of the alpha beta superfamily
LRX85_05885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LRX85_05895	COG2195	Cleaves the N-terminal amino acid of tripeptides
LRX85_05900	COG1234	tRNA 3'-trailer cleavage
LRX85_05930	COG2363	Small membrane protein
LRX85_05955	COG0513	Belongs to the DEAD box helicase family
LRX85_05965	COG0778	Nitroreductase
LRX85_05995	COG1286	toxin biosynthetic process
LRX85_06020	COG4783	chaperone-mediated protein folding
LRX85_06025	COG1610	YqeY-like protein
LRX85_06080	COG2831	hemolysin activation secretion protein
LRX85_06085	COG3210	domain, Protein
LRX85_06085	COG3210	domain, Protein
LRX85_06155	COG3111	PFAM Bacterial OB fold (BOF) protein
LRX85_06180	COG3243	poly(R)-hydroxyalkanoic acid synthase
LRX85_06185	COG0786	glutamate:sodium symporter activity
LRX85_06195	COG2186	Transcriptional regulator
LRX85_06245	COG0477	Major facilitator Superfamily
LRX85_06270	COG2995	paraquat-inducible protein a
LRX85_06275	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LRX85_06275	COG3008	intermembrane lipid transfer
LRX85_06285	COG2351	hydroxyisourate hydrolase activity
LRX85_06325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LRX85_06335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LRX85_06340	COG0642	Histidine kinase
LRX85_06345	COG0745	RESPONSE REGULATOR receiver
LRX85_06365	COG1794	racemase activity, acting on amino acids and derivatives
LRX85_06405	COG1301	dicarboxylic acid transport
LRX85_06420	COG2011	ABC-type metal ion transport system permease component
LRX85_06425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LRX85_06430	COG1464	Belongs to the NlpA lipoprotein family
LRX85_06435	COG0151	Belongs to the GarS family
LRX85_06440	COG0138	bifunctional purine biosynthesis protein purh
LRX85_06445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LRX85_06475	COG2308	Evidence 4 Homologs of previously reported genes of
LRX85_06485	COG1305	Transglutaminase-like
LRX85_06495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LRX85_06500	COG0305	Participates in initiation and elongation during chromosome replication
LRX85_06525	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LRX85_06535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LRX85_06540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LRX85_06565	COG0726	polysaccharide deacetylase
LRX85_06565	COG1649	PFAM Uncharacterised BCR, COG1649
LRX85_06570	COG1215	transferase activity, transferring glycosyl groups
LRX85_06575	COG3658	cytochrome
LRX85_06585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRX85_06600	COG0583	DNA-binding transcription factor activity
LRX85_06630	COG1960	acyl-CoA dehydrogenase activity
LRX85_06635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LRX85_06640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRX85_06665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LRX85_06670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LRX85_06680	COG2205	protein histidine kinase activity
LRX85_06685	COG0745	RESPONSE REGULATOR receiver
LRX85_06690	COG0174	glutamine synthetase
LRX85_06710	COG0729	surface antigen
LRX85_06735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LRX85_06740	COG2814	Major facilitator Superfamily
LRX85_06755	COG0583	DNA-binding transcription factor activity
LRX85_06770	COG1187	pseudouridine synthase activity
LRX85_06790	COG0802	atpase or kinase
LRX85_06795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LRX85_06805	COG1923	regulation of RNA biosynthetic process
LRX85_06810	COG0697	spore germination
LRX85_06820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRX85_06830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LRX85_06835	COG0519	Catalyzes the synthesis of GMP from XMP
LRX85_06835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LRX85_06840	COG4302	ethanolamine ammonia-lyase activity
LRX85_06845	COG4303	Ethanolamine ammonia lyase large subunit
LRX85_06850	COG0531	amino acid
LRX85_06870	COG1454	alcohol dehydrogenase
LRX85_06875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LRX85_06900	COG0308	aminopeptidase N
LRX85_06940	COG1605	Chorismate mutase
LRX85_06960	COG1309	transcriptional regulator
LRX85_06970	COG0668	transmembrane transport
LRX85_07000	COG4773	Receptor
LRX85_07020	COG0488	(ABC) transporter
LRX85_07025	COG0589	response to stress
LRX85_07050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LRX85_07075	COG1522	sequence-specific DNA binding
LRX85_07085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LRX85_07090	COG0583	DNA-binding transcription factor activity
LRX85_07100	COG0183	Belongs to the thiolase family
LRX85_07110	COG2030	dehydratase
LRX85_07115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LRX85_07130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LRX85_07140	COG0824	Thioesterase
LRX85_07145	COG1454	alcohol dehydrogenase
LRX85_07155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LRX85_07175	COG0069	glutamate synthase activity
LRX85_07195	COG2814	Major facilitator Superfamily
LRX85_07210	COG0511	ligase activity, forming carbon-carbon bonds
LRX85_07230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRX85_07230	COG1116	anion transmembrane transporter activity
LRX85_07235	COG0745	RESPONSE REGULATOR receiver
LRX85_07245	COG2146	nitrite reductase [NAD(P)H] activity
LRX85_07245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRX85_07250	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRX85_07255	COG0243	molybdopterin cofactor binding
LRX85_07265	COG0243	molybdopterin cofactor binding
LRX85_07270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LRX85_07285	COG0315	cyclic pyranopterin monophosphate synthase activity
LRX85_07285	COG0521	Mo-molybdopterin cofactor biosynthetic process
LRX85_07290	COG0303	'Molybdopterin
LRX85_07300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRX85_07305	COG0697	spore germination
LRX85_07325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LRX85_07330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LRX85_07385	COG2204	response regulator
LRX85_07390	COG3852	Histidine kinase
LRX85_07410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LRX85_07415	COG0575	Belongs to the CDS family
LRX85_07430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LRX85_07450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRX85_07465	COG2137	regulation of response to DNA damage stimulus
LRX85_07475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LRX85_07505	COG1522	sequence-specific DNA binding
LRX85_07515	COG1113	amino acid transport
LRX85_07535	COG0659	secondary active sulfate transmembrane transporter activity
LRX85_07540	COG2135	peptidase activity
LRX85_07555	COG3300	MHYT domain
LRX85_07555	COG5001	Diguanylate cyclase
LRX85_07570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LRX85_07570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LRX85_07570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LRX85_07575	COG1105	Belongs to the carbohydrate kinase PfkB family
LRX85_07580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LRX85_07580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LRX85_07610	COG0024	Methionine aminopeptidase
LRX85_07615	COG0583	DNA-binding transcription factor activity
LRX85_07625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LRX85_07630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LRX85_07635	COG0517	IMP dehydrogenase activity
LRX85_07635	COG0516	GMP reductase activity
LRX85_07660	COG0552	protein localization to endoplasmic reticulum
LRX85_07670	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LRX85_07680	COG4890	Cyd operon protein YbgT
LRX85_07685	COG1294	oxidase, subunit
LRX85_07700	COG1585	Membrane protein implicated in regulation of membrane protease activity
LRX85_07710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LRX85_07715	COG4774	siderophore transport
LRX85_07730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LRX85_07735	COG0569	domain protein
LRX85_07740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LRX85_07770	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LRX85_07775	COG0542	response to heat
LRX85_07800	COG1902	pentaerythritol trinitrate reductase activity
LRX85_07800	COG0446	pyridine nucleotide-disulphide oxidoreductase
LRX85_07845	COG2323	membrane
LRX85_07850	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LRX85_07860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRX85_07865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRX85_07870	COG0183	Belongs to the thiolase family
LRX85_07875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LRX85_07880	COG0596	Alpha beta hydrolase
LRX85_07885	COG2271	Major facilitator Superfamily
LRX85_07890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LRX85_07895	COG3485	protocatechuate 3,4-dioxygenase
LRX85_07900	COG3485	protocatechuate 3,4-dioxygenase
LRX85_07905	COG0710	3-dehydroquinate dehydratase activity
LRX85_07910	COG3420	alginic acid biosynthetic process
LRX85_07915	COG3659	wide pore channel activity
LRX85_07920	COG4993	Dehydrogenase
LRX85_07930	COG2391	methyltransferase activity
LRX85_07945	COG1414	Transcriptional regulator
LRX85_07950	COG0583	DNA-binding transcription factor activity
LRX85_07955	COG1960	acyl-CoA dehydrogenase activity
LRX85_07980	COG2814	Major facilitator Superfamily
LRX85_07990	COG0154	amidase activity
LRX85_08010	COG4638	Rieske (2fe-2S)
LRX85_08020	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_08030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRX85_08040	COG3733	amine oxidase
LRX85_08050	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_08060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRX85_08065	COG0183	Belongs to the thiolase family
LRX85_08070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRX85_08075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRX85_08085	COG4829	muconolactone delta-isomerase
LRX85_08090	COG4948	Mandelate Racemase Muconate Lactonizing
LRX85_08095	COG0583	DNA-binding transcription factor activity
LRX85_08105	COG2186	Transcriptional regulator
LRX85_08125	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_08140	COG1902	pentaerythritol trinitrate reductase activity
LRX85_08140	COG0446	pyridine nucleotide-disulphide oxidoreductase
LRX85_08155	COG0789	Transcriptional regulator
LRX85_08180	COG1309	transcriptional regulator
LRX85_08225	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LRX85_08230	COG2259	Doxx family
LRX85_08245	COG1733	regulation of RNA biosynthetic process
LRX85_08250	COG4993	Dehydrogenase
LRX85_08290	COG2188	Transcriptional regulator
LRX85_08305	COG0583	DNA-binding transcription factor activity
LRX85_08320	COG1566	PFAM secretion protein HlyD family protein
LRX85_08335	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_08340	COG0129	dihydroxy-acid dehydratase activity
LRX85_08350	COG0583	DNA-binding transcription factor activity
LRX85_08355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LRX85_08365	COG2084	Dehydrogenase
LRX85_08370	COG2207	Transcriptional regulator
LRX85_08380	COG1064	alcohol dehydrogenase
LRX85_08390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LRX85_08395	COG1120	ATPase activity
LRX85_08415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LRX85_08465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LRX85_08535	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_08550	COG2207	Transcriptional regulator
LRX85_08560	COG2205	protein histidine kinase activity
LRX85_08565	COG0745	RESPONSE REGULATOR receiver
LRX85_08575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_08580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRX85_08595	COG3539	Fimbrial protein
LRX85_08620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LRX85_08630	COG0753	catalase activity
LRX85_08645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LRX85_08705	COG3433	isochorismatase activity
LRX85_08705	COG1535	isochorismatase
LRX85_08710	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_08715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LRX85_08720	COG4149	molybdate abc transporter
LRX85_08725	COG0725	ABC transporter, periplasmic molybdate-binding protein
LRX85_08735	COG4638	Rieske (2fe-2S)
LRX85_08740	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LRX85_08745	COG0543	2 iron, 2 sulfur cluster binding
LRX85_08745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRX85_08760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRX85_08770	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_08785	COG2207	Transcriptional regulator
LRX85_08790	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_08795	COG2610	gluconate transmembrane transporter activity
LRX85_08805	COG1309	transcriptional regulator
LRX85_08825	COG0583	DNA-binding transcription factor activity
LRX85_08840	COG2031	fatty acid transporter
LRX85_08845	COG0183	Belongs to the thiolase family
LRX85_08850	COG0583	DNA-binding transcription factor activity
LRX85_08855	COG0583	DNA-binding transcription factor activity
LRX85_08870	COG1027	Aspartate ammonia-lyase
LRX85_08880	COG0477	Major facilitator Superfamily
LRX85_08900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRX85_08905	COG4521	taurine ABC transporter
LRX85_08920	COG2188	Transcriptional regulator
LRX85_08930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LRX85_08935	COG1733	regulation of RNA biosynthetic process
LRX85_08940	COG3708	Transcriptional regulator
LRX85_08940	COG2207	Transcriptional regulator
LRX85_08970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRX85_08970	COG3453	Protein conserved in bacteria
LRX85_08980	COG3781	membrane
LRX85_08985	COG1063	alcohol dehydrogenase
LRX85_08995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LRX85_09000	COG0508	dehydrogenase complex catalyzes the overall conversion of
LRX85_09005	COG0022	dehydrogenase e1 component
LRX85_09010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LRX85_09015	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LRX85_09030	COG3706	GGDEF domain
LRX85_09045	COG0133	tryptophan synthase activity
LRX85_09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LRX85_09090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LRX85_09115	COG2226	methyltransferase
LRX85_09170	COG0842	Transport permease protein
LRX85_09175	COG0842	Transport permease protein
LRX85_09180	COG1131	(ABC) transporter
LRX85_09195	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LRX85_09230	COG0730	response to heat
LRX85_09235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LRX85_09270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LRX85_09300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LRX85_09310	COG4264	IucA IucC family
LRX85_09315	COG4264	IucA IucC family
LRX85_09320	COG2814	Major facilitator Superfamily
LRX85_09335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LRX85_09380	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LRX85_09385	COG2207	Transcriptional regulator
LRX85_09390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LRX85_09395	COG0776	regulation of translation
LRX85_09420	COG0822	iron-sulfur transferase activity
LRX85_09425	COG0316	Belongs to the HesB IscA family
LRX85_09455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LRX85_09475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LRX85_09480	COG0702	epimerase
LRX85_09515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LRX85_09525	COG0339	signal peptide processing
LRX85_09570	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LRX85_09575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LRX85_09605	COG0776	regulation of translation
LRX85_09670	COG0084	hydrolase, TatD family'
LRX85_09690	COG1663	tetraacyldisaccharide 4'-kinase activity
LRX85_09695	COG1132	(ABC) transporter
LRX85_09705	COG0811	peptide transport
LRX85_09710	COG1475	DNA binding
LRX85_09715	COG1192	Involved in chromosome partitioning
LRX85_09725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LRX85_09740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LRX85_09745	COG0191	fructose-bisphosphate aldolase activity
LRX85_09765	COG0424	maF-like protein
LRX85_09770	COG2850	peptidyl-arginine hydroxylation
LRX85_09780	COG0640	Transcriptional regulator
LRX85_09790	COG3619	membrane
LRX85_09795	COG3122	Protein conserved in bacteria
LRX85_09800	COG1132	(ABC) transporter
LRX85_09820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LRX85_09825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LRX85_09835	COG0506	proline dehydrogenase activity
LRX85_09835	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LRX85_09835	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LRX85_09840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LRX85_09855	COG3698	Phosphodiester glycosidase
LRX85_09865	COG2353	YceI-like domain
LRX85_09875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LRX85_09920	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LRX85_09920	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LRX85_09945	COG3539	Fimbrial protein
LRX85_09950	COG3121	Chaperone
LRX85_09975	COG0697	spore germination
LRX85_09985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LRX85_09995	COG0583	DNA-binding transcription factor activity
LRX85_10015	COG1309	transcriptional regulator
LRX85_10030	COG1522	sequence-specific DNA binding
LRX85_10040	COG1126	abc transporter atp-binding protein
LRX85_10045	COG0765	amino acid transport
LRX85_10050	COG0765	amino acid transport
LRX85_10080	COG1464	Belongs to the NlpA lipoprotein family
LRX85_10090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LRX85_10095	COG2011	ABC-type metal ion transport system permease component
LRX85_10100	COG0012	GTP binding
LRX85_10125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LRX85_10165	COG0386	Belongs to the glutathione peroxidase family
LRX85_10175	COG0436	Aminotransferase
LRX85_10215	COG3634	alkyl hydroperoxide reductase activity
LRX85_10230	COG0583	DNA-binding transcription factor activity
LRX85_10235	COG0798	PFAM Bile acid sodium symporter
LRX85_10240	COG0640	Transcriptional regulator
LRX85_10255	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LRX85_10265	COG0583	DNA-binding transcription factor activity
LRX85_10275	COG1953	Uracil, thiamine, allantoin
LRX85_10285	COG2175	clavaminate synthase activity
LRX85_10290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRX85_10295	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LRX85_10300	COG4521	taurine ABC transporter
LRX85_10315	COG0477	Major facilitator Superfamily
LRX85_10335	COG1271	oxidase subunit
LRX85_10340	COG1294	oxidase, subunit
LRX85_10380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LRX85_10400	COG3052	prosthetic group binding
LRX85_10405	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LRX85_10415	COG0583	DNA-binding transcription factor activity
LRX85_10425	COG2814	Major facilitator Superfamily
LRX85_10445	COG1346	cytolysis
LRX85_10455	COG0583	DNA-binding transcription factor activity
LRX85_10460	COG0625	glutathione transferase activity
LRX85_10465	COG0625	glutathione transferase activity
LRX85_10470	COG0583	DNA-binding transcription factor activity
LRX85_10485	COG1045	serine acetyltransferase
LRX85_10490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LRX85_10495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LRX85_10500	COG1280	lysine exporter protein (LysE YggA)
LRX85_10515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRX85_10520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LRX85_10525	COG1126	abc transporter atp-binding protein
LRX85_10530	COG0765	amino acid transport
LRX85_10535	COG0765	amino acid transport
LRX85_10555	COG0784	Response regulator, receiver
LRX85_10555	COG2205	protein histidine kinase activity
LRX85_10575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LRX85_10600	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_10650	COG0583	DNA-binding transcription factor activity
LRX85_10670	COG0318	PFAM AMP-dependent synthetase and ligase
LRX85_10675	COG1309	transcriptional regulator
LRX85_10680	COG1960	acyl-CoA dehydrogenase activity
LRX85_10685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LRX85_10690	COG1024	Enoyl-CoA hydratase
LRX85_10695	COG4770	biotin carboxylase activity
LRX85_10705	COG0583	DNA-binding transcription factor activity
LRX85_10720	COG1960	acyl-CoA dehydrogenase activity
LRX85_10730	COG2814	Major facilitator Superfamily
LRX85_10740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LRX85_10745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LRX85_10750	COG2814	Major facilitator Superfamily
LRX85_10755	COG1960	acyl-CoA dehydrogenase activity
LRX85_10760	COG1024	Enoyl-CoA hydratase
LRX85_10765	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_10770	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRX85_10775	COG0183	Belongs to the thiolase family
LRX85_10785	COG2814	Major facilitator Superfamily
LRX85_10810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LRX85_10815	COG1960	acyl-CoA dehydrogenase activity
LRX85_10820	COG2814	Major facilitator Superfamily
LRX85_10825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LRX85_10830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LRX85_10845	COG3842	ATPase activity
LRX85_10850	COG1840	ABC-type Fe3 transport system, periplasmic component
LRX85_10860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRX85_10865	COG1414	Transcriptional regulator
LRX85_10875	COG0583	DNA-binding transcription factor activity
LRX85_10880	COG3038	cytochrome b561
LRX85_10885	COG0753	catalase activity
LRX85_10890	COG2271	Major facilitator Superfamily
LRX85_10895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LRX85_10900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LRX85_10915	COG2207	Transcriptional regulator
LRX85_10950	COG2050	protein possibly involved in aromatic compounds catabolism
LRX85_10960	COG3327	negative regulation of DNA-templated transcription, initiation
LRX85_10965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LRX85_10970	COG0183	Belongs to the thiolase family
LRX85_10975	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRX85_10980	COG1024	Enoyl-CoA hydratase
LRX85_10985	COG1024	Enoyl-CoA hydratase
LRX85_10990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRX85_10995	COG2151	metal-sulfur cluster biosynthetic enzyme
LRX85_11000	COG3396	Phenylacetate-CoA oxygenase
LRX85_11005	COG3460	Phenylacetate-CoA oxygenase
LRX85_11010	COG3396	Phenylacetate-CoA oxygenase
LRX85_11015	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_11015	COG2030	dehydratase
LRX85_11020	COG1760	l-serine dehydratase
LRX85_11025	COG0531	amino acid
LRX85_11030	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_11055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LRX85_11075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRX85_11085	COG0789	Transcriptional regulator
LRX85_11095	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LRX85_11110	COG1063	alcohol dehydrogenase
LRX85_11130	COG0038	chloride channel
LRX85_11135	COG4770	biotin carboxylase activity
LRX85_11155	COG1914	H( )-stimulated, divalent metal cation uptake system
LRX85_11160	COG0583	DNA-binding transcription factor activity
LRX85_11195	COG1250	3-hydroxyacyl-CoA dehydrogenase
LRX85_11215	COG2814	Major facilitator Superfamily
LRX85_11230	COG0598	Magnesium transport protein CorA
LRX85_11235	COG1560	Kdo2-lipid A biosynthetic process
LRX85_11245	COG5006	permease, DMT superfamily
LRX85_11250	COG1522	sequence-specific DNA binding
LRX85_11265	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LRX85_11275	COG4122	O-methyltransferase activity
LRX85_11305	COG1538	Outer membrane efflux protein
LRX85_11310	COG1137	ATPase activity
LRX85_11315	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LRX85_11325	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LRX85_11380	COG2814	Major facilitator Superfamily
LRX85_11415	COG1278	Cold shock
LRX85_11420	COG1280	lysine exporter protein (LysE YggA)
LRX85_11450	COG1570	exodeoxyribonuclease VII activity
LRX85_11500	COG0583	DNA-binding transcription factor activity
LRX85_11505	COG4638	Rieske (2fe-2S)
LRX85_11510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LRX85_11515	COG0633	Ferredoxin
LRX85_11515	COG0543	2 iron, 2 sulfur cluster binding
LRX85_11520	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_11525	COG3135	benzoate transporter
LRX85_11530	COG2814	Major facilitator Superfamily
LRX85_11545	COG1643	Atp-dependent helicase
LRX85_11550	COG0450	alkyl hydroperoxide reductase
LRX85_11560	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LRX85_11570	COG3634	alkyl hydroperoxide reductase activity
LRX85_11590	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LRX85_11595	COG0625	glutathione transferase activity
LRX85_11605	COG2885	chlorophyll binding
LRX85_11640	COG0542	response to heat
LRX85_11655	COG1765	OsmC-like protein
LRX85_11670	COG0667	Aldo Keto reductase
LRX85_11685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LRX85_11695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LRX85_11705	COG0582	viral genome integration into host DNA
LRX85_12050	COG0527	aspartate kinase activity
LRX85_12060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LRX85_12070	COG3038	cytochrome b561
LRX85_12080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LRX85_12085	COG2252	PERMEase
LRX85_12095	COG2072	flavoprotein involved in K transport
LRX85_12110	COG1741	Belongs to the pirin family
LRX85_12115	COG1309	transcriptional regulator
LRX85_12125	COG0300	oxidoreductase activity
LRX85_12130	COG2072	flavoprotein involved in K transport
LRX85_12135	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LRX85_12180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LRX85_12195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LRX85_12210	COG2814	Major facilitator Superfamily
LRX85_12215	COG1024	Enoyl-CoA hydratase
LRX85_12220	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_12230	COG1960	acyl-CoA dehydrogenase activity
LRX85_12255	COG2186	Transcriptional regulator
LRX85_12260	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_12270	COG4948	Mandelate Racemase Muconate Lactonizing
LRX85_12275	COG2271	Major facilitator Superfamily
LRX85_12280	COG2721	sulfolactate sulfo-lyase activity
LRX85_12285	COG0697	spore germination
LRX85_12300	COG1113	amino acid transport
LRX85_12320	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_12340	COG0531	amino acid
LRX85_12350	COG1113	amino acid transport
LRX85_12415	COG3209	COG3209 Rhs family protein
LRX85_12525	COG1902	pentaerythritol trinitrate reductase activity
LRX85_12525	COG0446	pyridine nucleotide-disulphide oxidoreductase
LRX85_12535	COG3706	GGDEF domain
LRX85_12535	COG5001	Diguanylate cyclase
LRX85_12535	COG2203	Gaf domain
LRX85_12535	COG4251	negative regulation of phosphorylation
LRX85_12545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LRX85_12565	COG4172	Belongs to the ABC transporter superfamily
LRX85_12570	COG4239	(ABC) transporter, permease
LRX85_12575	COG4174	ABC transporter (Permease)
LRX85_12585	COG1388	LysM domain
LRX85_12585	COG0741	lytic transglycosylase activity
LRX85_12585	COG0741	lytic transglycosylase activity
LRX85_12585	COG1388	LysM domain
LRX85_12590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LRX85_12630	COG0583	DNA-binding transcription factor activity
LRX85_12635	COG1279	arginine transmembrane transporter activity
LRX85_12655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRX85_12660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LRX85_12665	COG0006	proline dipeptidase activity
LRX85_12705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LRX85_12740	COG3384	dioxygenase
LRX85_12750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LRX85_12755	COG2878	Part of a membrane complex involved in electron transport
LRX85_12760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LRX85_12785	COG0768	penicillin binding
LRX85_12790	COG0742	ribosomal rna small subunit methyltransferase
LRX85_12805	COG0830	nickel cation binding
LRX85_12815	COG0804	urea catabolic process
LRX85_12855	COG1253	flavin adenine dinucleotide binding
LRX85_12860	COG2851	Citrate transporter
LRX85_12910	COG1773	rubredoxin
LRX85_12915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LRX85_12925	COG0583	DNA-binding transcription factor activity
LRX85_12950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LRX85_12955	COG4181	ATPase activity
LRX85_12980	COG4771	TonB-dependent receptor
LRX85_13000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LRX85_13020	COG0306	phosphate transporter
LRX85_13045	COG3958	Transketolase
LRX85_13050	COG3959	Transketolase, thiamine diphosphate binding domain
LRX85_13060	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_13065	COG0583	DNA-binding transcription factor activity
LRX85_13080	COG2223	nitrite transmembrane transporter activity
LRX85_13085	COG2207	Transcriptional regulator
LRX85_13090	COG2066	Belongs to the glutaminase family
LRX85_13095	COG0242	peptide deformylase activity
LRX85_13100	COG0477	Major facilitator Superfamily
LRX85_13110	COG0028	Belongs to the TPP enzyme family
LRX85_13125	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_13130	COG2267	carboxylic ester hydrolase activity
LRX85_13140	COG2271	Major facilitator Superfamily
LRX85_13155	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_13175	COG1414	Transcriptional regulator
LRX85_13190	COG1024	Enoyl-CoA hydratase
LRX85_13200	COG1215	transferase activity, transferring glycosyl groups
LRX85_13205	COG0726	polysaccharide deacetylase
LRX85_13205	COG1649	PFAM Uncharacterised BCR, COG1649
LRX85_13215	COG4681	YaeQ
LRX85_13225	COG0523	cobalamin synthesis protein
LRX85_13235	COG1607	acyl-coa hydrolase
LRX85_13245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRX85_13250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LRX85_13255	COG1309	transcriptional regulator
LRX85_13280	COG2040	homocysteine
LRX85_13285	COG0531	amino acid
LRX85_13340	COG1595	DNA-templated transcription, initiation
LRX85_13350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRX85_13355	COG0477	Major facilitator Superfamily
LRX85_13395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LRX85_13410	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LRX85_13420	COG1401	restriction endodeoxyribonuclease activity
LRX85_13420	COG1401	restriction endodeoxyribonuclease activity
LRX85_13430	COG0405	Gamma-glutamyltransferase
LRX85_13435	COG2814	Major facilitator Superfamily
LRX85_13445	COG2050	protein possibly involved in aromatic compounds catabolism
LRX85_13460	COG1090	epimerase
LRX85_13480	COG0420	3'-5' exonuclease activity
LRX85_13505	COG0735	belongs to the Fur family
LRX85_13510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LRX85_13530	COG0121	glutamine amidotransferase
LRX85_13545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LRX85_13555	COG0210	DNA helicase
LRX85_13560	COG2885	chlorophyll binding
LRX85_13565	COG0204	Acyl-transferase
LRX85_13580	COG2894	cell division
LRX85_13595	COG1280	lysine exporter protein (LysE YggA)
LRX85_13600	COG1674	ftsk spoiiie
LRX85_13600	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LRX85_13605	COG0492	ferredoxin-NADP+ reductase activity
LRX85_13610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LRX85_13620	COG0456	acetyltransferase
LRX85_13665	COG1981	membrane
LRX85_13680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LRX85_13680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LRX85_13700	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_13710	COG0657	acetylesterase activity
LRX85_13720	COG0473	3-isopropylmalate dehydrogenase activity
LRX85_13725	COG0583	DNA-binding transcription factor activity
LRX85_13745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LRX85_13770	COG0564	pseudouridine synthase activity
LRX85_13780	COG0358	DNA primase activity
LRX85_13795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LRX85_13825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LRX85_13855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LRX85_13865	COG0351	phosphomethylpyrimidine kinase
LRX85_13865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LRX85_13865	COG0352	thiamine-phosphate diphosphorylase activity
LRX85_13870	COG1652	LysM domain
LRX85_13895	COG1399	metal-binding, possibly nucleic acid-binding protein
LRX85_13900	COG3101	peptidyl-lysine hydroxylation
LRX85_13905	COG0009	L-threonylcarbamoyladenylate synthase
LRX85_13910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LRX85_13915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LRX85_13935	COG4106	trans-aconitate 2-methyltransferase activity
LRX85_13950	COG2226	methyltransferase
LRX85_13950	COG0596	Alpha beta hydrolase
LRX85_13950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRX85_13955	COG1877	trehalose-phosphatase activity
LRX85_13960	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LRX85_13965	COG2223	nitrite transmembrane transporter activity
LRX85_13985	COG1196	nuclear chromosome segregation
LRX85_13995	COG0730	response to heat
LRX85_14010	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LRX85_14020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LRX85_14075	COG0489	protein tyrosine kinase activity
LRX85_14085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRX85_14085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRX85_14115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LRX85_14120	COG2081	HI0933 family
LRX85_14130	COG0668	transmembrane transport
LRX85_14150	COG0583	DNA-binding transcription factor activity
LRX85_14170	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LRX85_14175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LRX85_14205	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LRX85_14245	COG0745	RESPONSE REGULATOR receiver
LRX85_14265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LRX85_14315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LRX85_14330	COG0583	DNA-binding transcription factor activity
LRX85_14340	COG0583	DNA-binding transcription factor activity
LRX85_14355	COG0583	DNA-binding transcription factor activity
LRX85_14360	COG1053	succinate dehydrogenase
LRX85_14375	COG1309	transcriptional regulator
LRX85_14380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LRX85_14385	COG2814	Major facilitator Superfamily
LRX85_14390	COG1960	acyl-CoA dehydrogenase activity
LRX85_14395	COG0583	DNA-binding transcription factor activity
LRX85_14400	COG1063	alcohol dehydrogenase
LRX85_14415	COG0582	viral genome integration into host DNA
LRX85_14425	COG0629	single-stranded DNA binding
LRX85_14560	COG5301	cellulose 1,4-beta-cellobiosidase activity
LRX85_14640	COG4695	Portal protein
LRX85_14650	COG1724	mRNA binding
LRX85_14655	COG1598	PFAM Uncharacterised protein family UPF0150
LRX85_14680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LRX85_14685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LRX85_14690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LRX85_14710	COG2132	Multicopper oxidase
LRX85_14720	COG0561	phosphatase activity
LRX85_14725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LRX85_14750	COG1214	PFAM Peptidase M22, glycoprotease
LRX85_14810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LRX85_14815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LRX85_14820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LRX85_14880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LRX85_14890	COG1846	Transcriptional regulator
LRX85_14895	COG1764	response to oxidative stress
LRX85_14935	COG0037	tRNA processing
LRX85_14945	COG0248	Ppx GppA phosphatase
LRX85_14975	COG0072	phenylalanine-tRNA ligase activity
LRX85_15020	COG1238	metal cluster binding
LRX85_15025	COG0625	glutathione transferase activity
LRX85_15040	COG0318	PFAM AMP-dependent synthetase and ligase
LRX85_15045	COG3028	Belongs to the UPF0307 family
LRX85_15050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LRX85_15070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LRX85_15075	COG0617	tRNA 3'-terminal CCA addition
LRX85_15080	COG1555	photosystem II stabilization
LRX85_15085	COG3956	TIGRFAM MazG family protein
LRX85_15095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LRX85_15115	COG5002	protein histidine kinase activity
LRX85_15115	COG2205	protein histidine kinase activity
LRX85_15115	COG0784	Response regulator, receiver
LRX85_15120	COG1024	Enoyl-CoA hydratase
LRX85_15125	COG2084	Dehydrogenase
LRX85_15130	COG3622	Belongs to the hyi family
LRX85_15160	COG0697	spore germination
LRX85_15170	COG2814	Major facilitator Superfamily
LRX85_15175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LRX85_15185	COG0583	DNA-binding transcription factor activity
LRX85_15195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LRX85_15210	COG0084	hydrolase, TatD family'
LRX85_15225	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LRX85_15260	COG0440	acetolactate synthase activity
LRX85_15265	COG0028	Belongs to the TPP enzyme family
LRX85_15290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_15295	COG0577	efflux transmembrane transporter activity
LRX85_15295	COG1136	(ABC) transporter
LRX85_15300	COG1538	Outer membrane efflux protein
LRX85_15315	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LRX85_15320	COG1162	GTPase activity
LRX85_15330	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LRX85_15370	COG1426	Protein conserved in bacteria
LRX85_15405	COG0793	Belongs to the peptidase S41A family
LRX85_15420	COG2267	carboxylic ester hydrolase activity
LRX85_15430	COG1012	belongs to the aldehyde dehydrogenase family
LRX85_15435	COG3265	gluconokinase activity
LRX85_15445	COG0800	Aldolase
LRX85_15455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LRX85_15460	COG0857	belongs to the CobB CobQ family
LRX85_15460	COG0280	phosphate acetyltransferase
LRX85_15465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LRX85_15465	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LRX85_15485	COG0740	serine-type endopeptidase activity
LRX85_15495	COG4774	siderophore transport
LRX85_15505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LRX85_15515	COG2813	Specifically methylates the guanine in position
LRX85_15515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LRX85_15615	COG0788	formyltetrahydrofolate deformylase activity
LRX85_15640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LRX85_15640	COG4651	solute:proton antiporter activity
LRX85_15660	COG0724	RNA recognition motif
LRX85_15665	COG0210	DNA helicase
LRX85_15690	COG1733	regulation of RNA biosynthetic process
LRX85_15700	COG2900	Belongs to the SlyX family
LRX85_15705	COG0488	(ABC) transporter
LRX85_15715	COG1280	lysine exporter protein (LysE YggA)
LRX85_15720	COG1560	Kdo2-lipid A biosynthetic process
LRX85_15730	COG1301	dicarboxylic acid transport
LRX85_15785	COG0473	3-isopropylmalate dehydrogenase activity
LRX85_15840	COG0583	DNA-binding transcription factor activity
LRX85_15850	COG0625	glutathione transferase activity
LRX85_15855	COG2378	regulation of single-species biofilm formation
LRX85_15860	COG0546	phosphoglycolate phosphatase activity
LRX85_15870	COG1530	ribonuclease E activity
LRX85_15875	COG0318	PFAM AMP-dependent synthetase and ligase
LRX85_15890	COG0583	DNA-binding transcription factor activity
LRX85_15895	COG4221	oxidoreductase activity
LRX85_15900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LRX85_15910	COG0534	Mate efflux family protein
LRX85_15925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LRX85_15950	COG0493	'glutamate synthase
LRX85_15950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LRX85_15960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LRX85_15965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LRX85_15980	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LRX85_15990	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LRX85_15990	COG0644	oxidoreductase
LRX85_16000	COG0425	Belongs to the sulfur carrier protein TusA family
LRX85_16005	COG4535	Mg2 and Co2 transporter CorC
LRX85_16015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LRX85_16035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LRX85_16040	COG0475	glutathione-regulated potassium exporter activity
LRX85_16040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LRX85_16055	COG0484	heat shock protein binding
LRX85_16060	COG0789	Transcriptional regulator
LRX85_16065	COG0598	Magnesium transport protein CorA
LRX85_16080	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LRX85_16085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LRX85_16090	COG1074	ATP-dependent DNA helicase activity
LRX85_16095	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LRX85_16115	COG2226	methyltransferase
LRX85_16135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LRX85_16150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LRX85_16150	COG2111	Na H antiporter
LRX85_16155	COG1006	Multisubunit Na H antiporter MnhC subunit
LRX85_16160	COG0651	ATP synthesis coupled electron transport
LRX85_16165	COG1863	multisubunit Na H antiporter MnhE subunit
LRX85_16170	COG2212	antiporter activity
LRX85_16175	COG1320	monovalent cation:proton antiporter activity
LRX85_16190	COG0195	Participates in both transcription termination and antitermination
LRX85_16240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LRX85_16245	COG0237	dephospho-CoA kinase activity
LRX85_16255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LRX85_16270	COG0497	DNA recombination
LRX85_16280	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LRX85_16310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LRX85_16310	COG2169	Transcriptional regulator
LRX85_16315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LRX85_16385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LRX85_16400	COG0326	Molecular chaperone. Has ATPase activity
LRX85_16415	COG2056	Na+-H+ antiporter family
LRX85_16515	COG0546	phosphoglycolate phosphatase activity
LRX85_16520	COG1716	ATPase activity
LRX85_16565	COG0181	hydroxymethylbilane synthase activity
LRX85_16575	COG3275	phosphorelay sensor kinase activity
LRX85_16595	COG1538	Outer membrane efflux protein
LRX85_16600	COG0697	spore germination
LRX85_16625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LRX85_16630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LRX85_16635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LRX85_16640	COG0772	Belongs to the SEDS family
LRX85_16665	COG4974	Belongs to the 'phage' integrase family
LRX85_16670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LRX85_16680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LRX85_16690	COG2197	response regulator
LRX85_16705	COG0793	Belongs to the peptidase S41A family
LRX85_16710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LRX85_16715	COG0795	lipopolysaccharide-transporting ATPase activity
LRX85_16755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LRX85_16755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LRX85_16765	COG0004	ammonium transporteR
LRX85_16770	COG0347	Belongs to the P(II) protein family
LRX85_16780	COG0606	chelatase, subunit chli
LRX85_16790	COG0235	Class ii aldolase
LRX85_16795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRX85_16810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LRX85_16825	COG0318	PFAM AMP-dependent synthetase and ligase
LRX85_16835	COG0477	Major facilitator Superfamily
LRX85_16840	COG2860	membrane
LRX85_16850	COG1253	flavin adenine dinucleotide binding
LRX85_16860	COG2814	Major facilitator Superfamily
LRX85_16870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LRX85_16910	COG0655	NAD(P)H dehydrogenase (quinone) activity
LRX85_16920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LRX85_16970	COG4771	TonB-dependent receptor
LRX85_16990	COG0758	DNA mediated transformation
LRX85_17000	COG0697	spore germination
LRX85_17005	COG1309	transcriptional regulator
LRX85_17020	COG0386	Belongs to the glutathione peroxidase family
LRX85_17085	COG1121	(ABC) transporter
LRX85_17090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LRX85_17095	COG1280	lysine exporter protein (LysE YggA)
LRX85_17100	COG2837	iron assimilation
LRX85_17105	COG0281	malic enzyme
LRX85_17150	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LRX85_17150	COG0519	Catalyzes the synthesis of GMP from XMP
LRX85_17155	COG4399	Belongs to the UPF0754 family
LRX85_17160	COG2259	Doxx family
LRX85_17165	COG0586	Pfam SNARE associated Golgi protein
LRX85_17180	COG1192	Involved in chromosome partitioning
LRX85_17190	COG0271	Belongs to the BolA IbaG family
LRX85_17230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LRX85_17230	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LRX85_17230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LRX85_17230	COG3321	synthase
LRX85_17235	COG1960	acyl-CoA dehydrogenase activity
LRX85_17245	COG2197	response regulator
LRX85_17255	COG3916	Acyl-homoserine-lactone synthase
LRX85_17260	COG0477	Major facilitator Superfamily
LRX85_17265	COG1024	Enoyl-CoA hydratase
LRX85_17270	COG1024	Enoyl-CoA hydratase
LRX85_17275	COG1960	acyl-CoA dehydrogenase activity
LRX85_17280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LRX85_17300	COG1113	amino acid transport
LRX85_17310	COG0251	oxidation-reduction process
LRX85_17350	COG0564	pseudouridine synthase activity
LRX85_17420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LRX85_17435	COG1802	Transcriptional regulator
LRX85_17445	COG1448	Aminotransferase
LRX85_17450	COG0277	FAD linked oxidase domain protein
LRX85_17460	COG2186	Transcriptional regulator
LRX85_17470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LRX85_17480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LRX85_17495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LRX85_17500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LRX85_17510	COG0438	transferase activity, transferring glycosyl groups
LRX85_17520	COG0438	transferase activity, transferring glycosyl groups
LRX85_17525	COG1215	transferase activity, transferring glycosyl groups
LRX85_17535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LRX85_17565	COG0728	peptidoglycan biosynthetic process
LRX85_17570	COG3023	N-Acetylmuramoyl-L-alanine amidase
LRX85_17625	COG0546	phosphoglycolate phosphatase activity
LRX85_17630	COG1028	Short-chain dehydrogenase reductase Sdr
LRX85_17665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LRX85_17670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LRX85_17675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LRX85_17680	COG1116	anion transmembrane transporter activity
LRX85_17685	COG1309	transcriptional regulator
LRX85_17690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LRX85_17700	COG0196	riboflavin kinase activity
LRX85_17705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LRX85_17715	COG1047	Peptidyl-prolyl cis-trans
LRX85_17755	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LRX85_17760	COG0657	acetylesterase activity
LRX85_17780	COG0583	DNA-binding transcription factor activity
LRX85_17810	COG2951	lytic endotransglycosylase activity
LRX85_17815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LRX85_17830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LRX85_17840	COG0671	phosphoesterase, PA-phosphatase related
LRX85_17845	COG0861	Integral membrane protein TerC family
LRX85_17855	COG0754	glutathionylspermidine amidase activity
LRX85_17865	COG0402	S-adenosylhomocysteine deaminase activity
LRX85_17880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LRX85_17885	COG1230	cation diffusion facilitator family transporter
LRX85_17900	COG0706	membrane insertase activity
LRX85_17925	COG0592	DNA-directed DNA polymerase activity
LRX85_17935	COG0187	DNA topoisomerase II activity
LRX85_17945	COG0586	Pfam SNARE associated Golgi protein
LRX85_17950	COG0488	(ABC) transporter
LRX85_17975	COG0596	Alpha beta hydrolase
LRX85_17980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LRX85_17985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LRX85_18025	COG0733	neurotransmitter:sodium symporter activity
LRX85_18060	COG0583	DNA-binding transcription factor activity
LRX85_18065	COG2233	PERMEase
LRX85_18080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LRX85_18115	COG2814	Major facilitator Superfamily
LRX85_18120	COG0656	L-ascorbic acid biosynthetic process
LRX85_18125	COG0583	DNA-binding transcription factor activity
LRX85_18140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LRX85_18145	COG1064	alcohol dehydrogenase
LRX85_18150	COG2818	Glycosylase
LRX85_18165	COG1194	a g-specific adenine glycosylase
LRX85_18175	COG0400	carboxylic ester hydrolase activity
LRX85_18185	COG2983	Belongs to the UPF0260 family
LRX85_18190	COG2133	pyrroloquinoline quinone binding
LRX85_18195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LRX85_18200	COG2116	formate transmembrane transporter activity
LRX85_18220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LRX85_18225	COG1335	isochorismatase
LRX85_18230	COG0385	Bile acid
LRX85_18235	COG0534	Mate efflux family protein
LRX85_18240	COG1683	Conserved Protein
LRX85_18260	COG0625	glutathione transferase activity
LRX85_18270	COG1113	amino acid transport
LRX85_18280	COG0523	cobalamin synthesis protein
LRX85_18290	COG2188	Transcriptional regulator
LRX85_18320	COG0010	Belongs to the arginase family
LRX85_18330	COG0546	phosphoglycolate phosphatase activity
LRX85_18380	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LRX85_18385	COG0732	type I restriction modification DNA specificity domain