locus-tag	class	description
AYR69_00010	COG0592	DNA-directed DNA polymerase activity
AYR69_00020	COG0187	DNA topoisomerase II activity
AYR69_00030	COG0586	Pfam SNARE associated Golgi protein
AYR69_00035	COG0488	(ABC) transporter
AYR69_00060	COG0596	Alpha beta hydrolase
AYR69_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYR69_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYR69_00110	COG1047	Peptidyl-prolyl cis-trans
AYR69_00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYR69_00125	COG0196	riboflavin kinase activity
AYR69_00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYR69_00140	COG1309	transcriptional regulator
AYR69_00145	COG1116	anion transmembrane transporter activity
AYR69_00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR69_00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR69_00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR69_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR69_00185	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_00190	COG0546	phosphoglycolate phosphatase activity
AYR69_00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYR69_00250	COG0728	peptidoglycan biosynthetic process
AYR69_00275	COG1596	polysaccharide export
AYR69_00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYR69_00290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AYR69_00305	COG2030	dehydratase
AYR69_00320	COG1216	Glycosyl transferase, family 2
AYR69_00320	COG0463	Glycosyl transferase, family 2
AYR69_00325	COG0438	transferase activity, transferring glycosyl groups
AYR69_00340	COG1216	Glycosyl transferase, family 2
AYR69_00345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYR69_00350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYR69_00365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYR69_00375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR69_00385	COG2186	Transcriptional regulator
AYR69_00395	COG0277	FAD linked oxidase domain protein
AYR69_00400	COG1448	Aminotransferase
AYR69_00405	COG1802	Transcriptional regulator
AYR69_00420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYR69_00455	COG0564	pseudouridine synthase activity
AYR69_00480	COG1522	sequence-specific DNA binding
AYR69_00495	COG0251	oxidation-reduction process
AYR69_00500	COG1113	amino acid transport
AYR69_00505	COG1113	amino acid transport
AYR69_00525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR69_00530	COG1960	acyl-CoA dehydrogenase activity
AYR69_00535	COG1024	Enoyl-CoA hydratase
AYR69_00540	COG1024	Enoyl-CoA hydratase
AYR69_00545	COG0477	Major facilitator Superfamily
AYR69_00550	COG3916	Acyl-homoserine-lactone synthase
AYR69_00560	COG2197	response regulator
AYR69_00570	COG2267	carboxylic ester hydrolase activity
AYR69_00590	COG0271	Belongs to the BolA IbaG family
AYR69_00600	COG1192	Involved in chromosome partitioning
AYR69_00615	COG0586	Pfam SNARE associated Golgi protein
AYR69_00620	COG2259	Doxx family
AYR69_00625	COG4399	Belongs to the UPF0754 family
AYR69_00630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYR69_00630	COG0519	Catalyzes the synthesis of GMP from XMP
AYR69_00675	COG0281	malic enzyme
AYR69_00680	COG2837	iron assimilation
AYR69_00685	COG1280	lysine exporter protein (LysE YggA)
AYR69_00690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYR69_00695	COG1121	(ABC) transporter
AYR69_00760	COG0386	Belongs to the glutathione peroxidase family
AYR69_00775	COG1309	transcriptional regulator
AYR69_00780	COG0697	spore germination
AYR69_00790	COG0758	DNA mediated transformation
AYR69_00825	COG1309	transcriptional regulator
AYR69_00860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYR69_00880	COG0655	NAD(P)H dehydrogenase (quinone) activity
AYR69_00915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYR69_00935	COG1253	flavin adenine dinucleotide binding
AYR69_00945	COG2860	membrane
AYR69_00950	COG0477	Major facilitator Superfamily
AYR69_00960	COG0318	PFAM AMP-dependent synthetase and ligase
AYR69_00975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYR69_01000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR69_01010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR69_01045	COG0589	response to stress
AYR69_01050	COG0659	secondary active sulfate transmembrane transporter activity
AYR69_01110	COG0347	Belongs to the P(II) protein family
AYR69_01115	COG0004	ammonium transporteR
AYR69_01125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR69_01125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR69_01165	COG0795	lipopolysaccharide-transporting ATPase activity
AYR69_01170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYR69_01175	COG0793	Belongs to the peptidase S41A family
AYR69_01190	COG2197	response regulator
AYR69_01200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYR69_01210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR69_01215	COG4974	Belongs to the 'phage' integrase family
AYR69_01240	COG0772	Belongs to the SEDS family
AYR69_01245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYR69_01250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYR69_01255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYR69_01280	COG0697	spore germination
AYR69_01285	COG1538	Outer membrane efflux protein
AYR69_01305	COG3275	phosphorelay sensor kinase activity
AYR69_01315	COG0181	hydroxymethylbilane synthase activity
AYR69_01360	COG1716	ATPase activity
AYR69_01365	COG0546	phosphoglycolate phosphatase activity
AYR69_01460	COG0596	Alpha beta hydrolase
AYR69_01465	COG2056	Na+-H+ antiporter family
AYR69_01480	COG0326	Molecular chaperone. Has ATPase activity
AYR69_01495	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AYR69_01560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYR69_01565	COG2169	Transcriptional regulator
AYR69_01565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYR69_01595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYR69_01605	COG0497	DNA recombination
AYR69_01620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR69_01630	COG0237	dephospho-CoA kinase activity
AYR69_01680	COG0195	Participates in both transcription termination and antitermination
AYR69_01700	COG2212	antiporter activity
AYR69_01710	COG0651	ATP synthesis coupled electron transport
AYR69_01715	COG1006	Multisubunit Na H antiporter MnhC subunit
AYR69_01720	COG2111	Na H antiporter
AYR69_01720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYR69_01735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYR69_01740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR69_01755	COG2226	methyltransferase
AYR69_01775	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYR69_01780	COG1074	ATP-dependent DNA helicase activity
AYR69_01785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYR69_01805	COG0598	Magnesium transport protein CorA
AYR69_01810	COG0789	Transcriptional regulator
AYR69_01815	COG0484	heat shock protein binding
AYR69_01825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYR69_01830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR69_01830	COG0475	glutathione-regulated potassium exporter activity
AYR69_01835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYR69_01855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR69_01865	COG4535	Mg2 and Co2 transporter CorC
AYR69_01870	COG0425	Belongs to the sulfur carrier protein TusA family
AYR69_01875	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYR69_01875	COG0644	oxidoreductase
AYR69_01885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYR69_01900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR69_01905	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AYR69_01945	COG1061	Type III restriction enzyme res subunit
AYR69_01980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYR69_01995	COG0534	Mate efflux family protein
AYR69_02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYR69_02010	COG4221	oxidoreductase activity
AYR69_02015	COG0583	DNA-binding transcription factor activity
AYR69_02035	COG1530	ribonuclease E activity
AYR69_02045	COG0546	phosphoglycolate phosphatase activity
AYR69_02050	COG2378	regulation of single-species biofilm formation
AYR69_02055	COG0625	glutathione transferase activity
AYR69_02065	COG0583	DNA-binding transcription factor activity
AYR69_02130	COG0473	3-isopropylmalate dehydrogenase activity
AYR69_02185	COG1301	dicarboxylic acid transport
AYR69_02195	COG1560	Kdo2-lipid A biosynthetic process
AYR69_02200	COG1280	lysine exporter protein (LysE YggA)
AYR69_02220	COG1733	regulation of RNA biosynthetic process
AYR69_02245	COG0210	DNA helicase
AYR69_02250	COG0724	RNA recognition motif
AYR69_02270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR69_02270	COG4651	solute:proton antiporter activity
AYR69_02275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYR69_02280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AYR69_02295	COG0788	formyltetrahydrofolate deformylase activity
AYR69_02395	COG2813	Specifically methylates the guanine in position
AYR69_02395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR69_02405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYR69_02415	COG4774	siderophore transport
AYR69_02425	COG0740	serine-type endopeptidase activity
AYR69_02445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYR69_02445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYR69_02450	COG0280	phosphate acetyltransferase
AYR69_02450	COG0857	belongs to the CobB CobQ family
AYR69_02455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYR69_02465	COG0800	Aldolase
AYR69_02475	COG3265	gluconokinase activity
AYR69_02480	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_02490	COG2267	carboxylic ester hydrolase activity
AYR69_02505	COG0793	Belongs to the peptidase S41A family
AYR69_02540	COG1426	Protein conserved in bacteria
AYR69_02580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR69_02585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR69_02595	COG0318	PFAM AMP-dependent synthetase and ligase
AYR69_02610	COG2986	histidine ammonia-lyase
AYR69_02650	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_02655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYR69_02675	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYR69_02685	COG1162	GTPase activity
AYR69_02690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AYR69_02705	COG1538	Outer membrane efflux protein
AYR69_02710	COG1136	(ABC) transporter
AYR69_02710	COG0577	efflux transmembrane transporter activity
AYR69_02715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_02740	COG0028	Belongs to the TPP enzyme family
AYR69_02745	COG0440	acetolactate synthase activity
AYR69_02775	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYR69_02790	COG0084	hydrolase, TatD family'
AYR69_02805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYR69_02810	COG0583	DNA-binding transcription factor activity
AYR69_02820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYR69_02825	COG2814	Major facilitator Superfamily
AYR69_02835	COG0697	spore germination
AYR69_02840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYR69_02845	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYR69_02850	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYR69_02865	COG3622	Belongs to the hyi family
AYR69_02870	COG2084	Dehydrogenase
AYR69_02875	COG1024	Enoyl-CoA hydratase
AYR69_02880	COG0784	Response regulator, receiver
AYR69_02880	COG2205	protein histidine kinase activity
AYR69_02880	COG5002	protein histidine kinase activity
AYR69_02900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYR69_02910	COG3956	TIGRFAM MazG family protein
AYR69_02915	COG1555	photosystem II stabilization
AYR69_02920	COG0617	tRNA 3'-terminal CCA addition
AYR69_02925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYR69_02945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR69_02950	COG3028	Belongs to the UPF0307 family
AYR69_02955	COG0318	PFAM AMP-dependent synthetase and ligase
AYR69_02970	COG0625	glutathione transferase activity
AYR69_02975	COG1238	metal cluster binding
AYR69_02990	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYR69_03015	COG0072	phenylalanine-tRNA ligase activity
AYR69_03040	COG0248	Ppx GppA phosphatase
AYR69_03050	COG0037	tRNA processing
AYR69_03090	COG1764	response to oxidative stress
AYR69_03095	COG1846	Transcriptional regulator
AYR69_03105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYR69_03165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYR69_03170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AYR69_03175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYR69_03185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYR69_03240	COG1214	PFAM Peptidase M22, glycoprotease
AYR69_03265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYR69_03270	COG0561	phosphatase activity
AYR69_03280	COG2132	Multicopper oxidase
AYR69_03285	COG3667	copper resistance
AYR69_03300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYR69_03305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYR69_03310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AYR69_03340	COG1063	alcohol dehydrogenase
AYR69_03345	COG0583	DNA-binding transcription factor activity
AYR69_03350	COG1960	acyl-CoA dehydrogenase activity
AYR69_03355	COG2814	Major facilitator Superfamily
AYR69_03360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYR69_03370	COG1053	succinate dehydrogenase
AYR69_03375	COG0583	DNA-binding transcription factor activity
AYR69_03390	COG0583	DNA-binding transcription factor activity
AYR69_03400	COG1473	amidohydrolase
AYR69_03420	COG0583	DNA-binding transcription factor activity
AYR69_03430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AYR69_03435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_03460	COG0384	phenazine biosynthesis protein PhzF
AYR69_03480	COG4993	Dehydrogenase
AYR69_03580	COG2205	protein histidine kinase activity
AYR69_03590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYR69_03610	COG0745	RESPONSE REGULATOR receiver
AYR69_03615	COG2205	protein histidine kinase activity
AYR69_03650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYR69_03680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYR69_03685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYR69_03705	COG0583	DNA-binding transcription factor activity
AYR69_03725	COG0668	transmembrane transport
AYR69_03735	COG2081	HI0933 family
AYR69_03740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AYR69_03770	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR69_03770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR69_03780	COG0489	protein tyrosine kinase activity
AYR69_03830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYR69_03840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYR69_03855	COG0730	response to heat
AYR69_03865	COG1196	nuclear chromosome segregation
AYR69_03885	COG2223	nitrite transmembrane transporter activity
AYR69_03890	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYR69_03895	COG1877	trehalose-phosphatase activity
AYR69_03900	COG2226	methyltransferase
AYR69_03900	COG0596	Alpha beta hydrolase
AYR69_03900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR69_03915	COG4106	trans-aconitate 2-methyltransferase activity
AYR69_03930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYR69_03935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYR69_03940	COG0009	L-threonylcarbamoyladenylate synthase
AYR69_03945	COG3101	peptidyl-lysine hydroxylation
AYR69_03950	COG1399	metal-binding, possibly nucleic acid-binding protein
AYR69_03975	COG1652	LysM domain
AYR69_03980	COG0351	phosphomethylpyrimidine kinase
AYR69_03980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYR69_03980	COG0352	thiamine-phosphate diphosphorylase activity
AYR69_03990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYR69_04020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR69_04050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AYR69_04065	COG0358	DNA primase activity
AYR69_04075	COG0564	pseudouridine synthase activity
AYR69_04100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYR69_04120	COG0583	DNA-binding transcription factor activity
AYR69_04125	COG0473	3-isopropylmalate dehydrogenase activity
AYR69_04145	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_04165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYR69_04165	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AYR69_04225	COG0456	acetyltransferase
AYR69_04235	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYR69_04240	COG0492	ferredoxin-NADP+ reductase activity
AYR69_04245	COG1674	ftsk spoiiie
AYR69_04245	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYR69_04250	COG1280	lysine exporter protein (LysE YggA)
AYR69_04270	COG2894	cell division
AYR69_04285	COG0204	Acyl-transferase
AYR69_04290	COG2885	chlorophyll binding
AYR69_04295	COG0210	DNA helicase
AYR69_04305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR69_04320	COG0121	glutamine amidotransferase
AYR69_04340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYR69_04345	COG0735	belongs to the Fur family
AYR69_04370	COG0420	3'-5' exonuclease activity
AYR69_04390	COG1090	epimerase
AYR69_04405	COG2050	protein possibly involved in aromatic compounds catabolism
AYR69_04415	COG2814	Major facilitator Superfamily
AYR69_04420	COG0405	Gamma-glutamyltransferase
AYR69_04485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR69_04575	COG1484	DNA-dependent DNA replication
AYR69_04620	COG3755	Protein conserved in bacteria
AYR69_04765	COG2026	Addiction module toxin, RelE StbE family
AYR69_04805	COG0592	DNA-directed DNA polymerase activity
AYR69_04900	COG0582	viral genome integration into host DNA
AYR69_04985	COG0084	hydrolase, TatD family'
AYR69_05005	COG0477	Major facilitator Superfamily
AYR69_05010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR69_05020	COG1595	DNA-templated transcription, initiation
AYR69_05075	COG0531	amino acid
AYR69_05080	COG2040	homocysteine
AYR69_05105	COG1309	transcriptional regulator
AYR69_05110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR69_05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR69_05125	COG1607	acyl-coa hydrolase
AYR69_05135	COG0523	cobalamin synthesis protein
AYR69_05145	COG4681	YaeQ
AYR69_05155	COG0726	polysaccharide deacetylase
AYR69_05155	COG1649	PFAM Uncharacterised BCR, COG1649
AYR69_05160	COG1215	transferase activity, transferring glycosyl groups
AYR69_05170	COG1024	Enoyl-CoA hydratase
AYR69_05175	COG1484	DNA-dependent DNA replication
AYR69_05180	COG2390	Transcriptional regulator
AYR69_05180	COG4584	PFAM Integrase catalytic
AYR69_05205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_05225	COG1414	Transcriptional regulator
AYR69_05245	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_05255	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR69_05260	COG2271	Major facilitator Superfamily
AYR69_05270	COG2267	carboxylic ester hydrolase activity
AYR69_05275	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_05290	COG0028	Belongs to the TPP enzyme family
AYR69_05300	COG0477	Major facilitator Superfamily
AYR69_05305	COG0242	peptide deformylase activity
AYR69_05310	COG2066	Belongs to the glutaminase family
AYR69_05315	COG2207	Transcriptional regulator
AYR69_05320	COG2223	nitrite transmembrane transporter activity
AYR69_05335	COG0583	DNA-binding transcription factor activity
AYR69_05340	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_05345	COG2271	Major facilitator Superfamily
AYR69_05350	COG3959	Transketolase, thiamine diphosphate binding domain
AYR69_05355	COG3958	Transketolase
AYR69_05365	COG0306	phosphate transporter
AYR69_05385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AYR69_05430	COG4181	ATPase activity
AYR69_05435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYR69_05460	COG0583	DNA-binding transcription factor activity
AYR69_05470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR69_05475	COG1773	rubredoxin
AYR69_05520	COG2851	Citrate transporter
AYR69_05530	COG1253	flavin adenine dinucleotide binding
AYR69_05580	COG0830	nickel cation binding
AYR69_05595	COG0742	ribosomal rna small subunit methyltransferase
AYR69_05600	COG0768	penicillin binding
AYR69_05620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYR69_05625	COG2878	Part of a membrane complex involved in electron transport
AYR69_05630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYR69_05640	COG3384	dioxygenase
AYR69_05665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYR69_06000	COG0739	heme binding
AYR69_06105	COG0006	proline dipeptidase activity
AYR69_06110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR69_06115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR69_06135	COG1279	arginine transmembrane transporter activity
AYR69_06140	COG0583	DNA-binding transcription factor activity
AYR69_06180	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR69_06185	COG0741	lytic transglycosylase activity
AYR69_06185	COG1388	LysM domain
AYR69_06185	COG0741	lytic transglycosylase activity
AYR69_06185	COG1388	LysM domain
AYR69_06195	COG4174	ABC transporter (Permease)
AYR69_06200	COG4239	(ABC) transporter, permease
AYR69_06205	COG4172	Belongs to the ABC transporter superfamily
AYR69_06225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR69_06235	COG3706	GGDEF domain
AYR69_06235	COG4251	negative regulation of phosphorylation
AYR69_06235	COG5001	Diguanylate cyclase
AYR69_06235	COG2203	Gaf domain
AYR69_06245	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR69_06245	COG1902	pentaerythritol trinitrate reductase activity
AYR69_06260	COG4269	membrane
AYR69_06265	COG3316	Transposase and inactivated derivatives
AYR69_06280	COG3316	Transposase and inactivated derivatives
AYR69_06290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYR69_06295	COG3316	Transposase and inactivated derivatives
AYR69_06310	COG3316	Transposase and inactivated derivatives
AYR69_06390	COG3111	PFAM Bacterial OB fold (BOF) protein
AYR69_06415	COG3243	poly(R)-hydroxyalkanoic acid synthase
AYR69_06420	COG0786	glutamate:sodium symporter activity
AYR69_06430	COG2186	Transcriptional regulator
AYR69_06470	COG3316	Transposase and inactivated derivatives
AYR69_06480	COG3316	Transposase and inactivated derivatives
AYR69_06550	COG3173	Aminoglycoside phosphotransferase
AYR69_06560	COG2433	Pfam Transposase IS66
AYR69_06585	COG3316	Transposase and inactivated derivatives
AYR69_06600	COG1301	dicarboxylic acid transport
AYR69_06610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR69_06615	COG2011	ABC-type metal ion transport system permease component
AYR69_06620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR69_06625	COG1464	Belongs to the NlpA lipoprotein family
AYR69_06630	COG0151	Belongs to the GarS family
AYR69_06635	COG0138	bifunctional purine biosynthesis protein purh
AYR69_06640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AYR69_06670	COG2308	Evidence 4 Homologs of previously reported genes of
AYR69_06680	COG1305	Transglutaminase-like
AYR69_06690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYR69_06695	COG0305	Participates in initiation and elongation during chromosome replication
AYR69_06720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYR69_06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYR69_06735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYR69_06760	COG0726	polysaccharide deacetylase
AYR69_06760	COG1649	PFAM Uncharacterised BCR, COG1649
AYR69_06765	COG1215	transferase activity, transferring glycosyl groups
AYR69_06770	COG3658	cytochrome
AYR69_06780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR69_06795	COG0583	DNA-binding transcription factor activity
AYR69_06815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR69_06820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR69_06835	COG1960	acyl-CoA dehydrogenase activity
AYR69_06840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR69_06845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_06870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AYR69_06875	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AYR69_06885	COG2205	protein histidine kinase activity
AYR69_06890	COG0745	RESPONSE REGULATOR receiver
AYR69_06895	COG0174	glutamine synthetase
AYR69_06915	COG0729	surface antigen
AYR69_06940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYR69_06945	COG2814	Major facilitator Superfamily
AYR69_06960	COG0583	DNA-binding transcription factor activity
AYR69_06975	COG1187	pseudouridine synthase activity
AYR69_06995	COG0802	atpase or kinase
AYR69_07000	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYR69_07010	COG1923	regulation of RNA biosynthetic process
AYR69_07045	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR69_07060	COG0519	Catalyzes the synthesis of GMP from XMP
AYR69_07060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYR69_07065	COG4302	ethanolamine ammonia-lyase activity
AYR69_07070	COG4303	Ethanolamine ammonia lyase large subunit
AYR69_07075	COG0531	amino acid
AYR69_07095	COG1454	alcohol dehydrogenase
AYR69_07100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYR69_07110	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYR69_07130	COG0308	aminopeptidase N
AYR69_07140	COG4221	oxidoreductase activity
AYR69_07150	COG1605	Chorismate mutase
AYR69_07165	COG1309	transcriptional regulator
AYR69_07175	COG0668	transmembrane transport
AYR69_07215	COG4773	Receptor
AYR69_07235	COG0488	(ABC) transporter
AYR69_07240	COG0589	response to stress
AYR69_07260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYR69_07270	COG3135	benzoate transporter
AYR69_07275	COG1522	sequence-specific DNA binding
AYR69_07290	COG0583	DNA-binding transcription factor activity
AYR69_07300	COG0183	Belongs to the thiolase family
AYR69_07330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYR69_07340	COG0824	Thioesterase
AYR69_07345	COG1454	alcohol dehydrogenase
AYR69_07355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYR69_07375	COG0069	glutamate synthase activity
AYR69_07395	COG2814	Major facilitator Superfamily
AYR69_07410	COG0511	ligase activity, forming carbon-carbon bonds
AYR69_07425	COG1116	anion transmembrane transporter activity
AYR69_07425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR69_07430	COG0745	RESPONSE REGULATOR receiver
AYR69_07440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR69_07440	COG2146	nitrite reductase [NAD(P)H] activity
AYR69_07445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR69_07450	COG0243	molybdopterin cofactor binding
AYR69_07460	COG0243	molybdopterin cofactor binding
AYR69_07465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AYR69_07480	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYR69_07480	COG0315	cyclic pyranopterin monophosphate synthase activity
AYR69_07485	COG0303	'Molybdopterin
AYR69_07495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR69_07500	COG0697	spore germination
AYR69_07520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AYR69_07525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYR69_07580	COG2204	response regulator
AYR69_07585	COG3852	Histidine kinase
AYR69_07605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYR69_07610	COG0575	Belongs to the CDS family
AYR69_07645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR69_07660	COG2137	regulation of response to DNA damage stimulus
AYR69_07670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYR69_07675	COG1011	Hydrolase
AYR69_07700	COG1522	sequence-specific DNA binding
AYR69_07710	COG1113	amino acid transport
AYR69_07725	COG0659	secondary active sulfate transmembrane transporter activity
AYR69_07730	COG2135	peptidase activity
AYR69_07745	COG3300	MHYT domain
AYR69_07745	COG5001	Diguanylate cyclase
AYR69_07765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR69_07765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYR69_07765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR69_07770	COG1105	Belongs to the carbohydrate kinase PfkB family
AYR69_07775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR69_07775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYR69_07805	COG0024	Methionine aminopeptidase
AYR69_07810	COG0583	DNA-binding transcription factor activity
AYR69_07820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYR69_07825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYR69_07830	COG0516	GMP reductase activity
AYR69_07830	COG0517	IMP dehydrogenase activity
AYR69_07855	COG0552	protein localization to endoplasmic reticulum
AYR69_07865	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AYR69_07880	COG4890	Cyd operon protein YbgT
AYR69_07885	COG1294	oxidase, subunit
AYR69_07905	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYR69_07915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYR69_07920	COG4774	siderophore transport
AYR69_07935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYR69_07940	COG0569	domain protein
AYR69_07945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYR69_07975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYR69_07980	COG0542	response to heat
AYR69_07990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYR69_08005	COG1902	pentaerythritol trinitrate reductase activity
AYR69_08005	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR69_08050	COG2323	membrane
AYR69_08055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AYR69_08065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR69_08070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR69_08075	COG0183	Belongs to the thiolase family
AYR69_08080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYR69_08085	COG0596	Alpha beta hydrolase
AYR69_08090	COG2271	Major facilitator Superfamily
AYR69_08095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYR69_08100	COG3485	protocatechuate 3,4-dioxygenase
AYR69_08105	COG3485	protocatechuate 3,4-dioxygenase
AYR69_08110	COG0710	3-dehydroquinate dehydratase activity
AYR69_08115	COG3420	alginic acid biosynthetic process
AYR69_08120	COG3659	wide pore channel activity
AYR69_08125	COG4993	Dehydrogenase
AYR69_08135	COG2391	methyltransferase activity
AYR69_08150	COG1414	Transcriptional regulator
AYR69_08155	COG0583	DNA-binding transcription factor activity
AYR69_08160	COG1960	acyl-CoA dehydrogenase activity
AYR69_08185	COG2814	Major facilitator Superfamily
AYR69_08195	COG0154	amidase activity
AYR69_08215	COG4638	Rieske (2fe-2S)
AYR69_08225	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_08235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_08245	COG3733	amine oxidase
AYR69_08255	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_08265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR69_08270	COG0183	Belongs to the thiolase family
AYR69_08275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR69_08280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR69_08290	COG4829	muconolactone delta-isomerase
AYR69_08295	COG4948	Mandelate Racemase Muconate Lactonizing
AYR69_08300	COG0583	DNA-binding transcription factor activity
AYR69_08310	COG2186	Transcriptional regulator
AYR69_08330	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_08350	COG1960	acyl-CoA dehydrogenase activity
AYR69_08355	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_08360	COG3829	transcription factor binding
AYR69_08370	COG3162	membrane
AYR69_08385	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_08400	COG0753	catalase activity
AYR69_08425	COG1846	Transcriptional regulator
AYR69_08430	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR69_08430	COG1902	pentaerythritol trinitrate reductase activity
AYR69_08440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AYR69_08470	COG1309	transcriptional regulator
AYR69_08480	COG1335	isochorismatase
AYR69_08485	COG0583	DNA-binding transcription factor activity
AYR69_08495	COG0475	glutathione-regulated potassium exporter activity
AYR69_08495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR69_08505	COG1473	amidohydrolase
AYR69_08525	COG2831	hemolysin activation secretion protein
AYR69_08530	COG3210	domain, Protein
AYR69_08575	COG0583	DNA-binding transcription factor activity
AYR69_08600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYR69_08605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYR69_08625	COG1566	PFAM secretion protein HlyD family protein
AYR69_08640	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_08645	COG0129	dihydroxy-acid dehydratase activity
AYR69_08655	COG0583	DNA-binding transcription factor activity
AYR69_08660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYR69_08670	COG2084	Dehydrogenase
AYR69_08675	COG2207	Transcriptional regulator
AYR69_08690	COG1064	alcohol dehydrogenase
AYR69_08705	COG1120	ATPase activity
AYR69_08725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR69_08840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYR69_08895	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_08925	COG2207	Transcriptional regulator
AYR69_08935	COG2205	protein histidine kinase activity
AYR69_08940	COG0745	RESPONSE REGULATOR receiver
AYR69_08945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_08950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYR69_08955	COG1538	Outer membrane efflux protein
AYR69_08965	COG2072	flavoprotein involved in K transport
AYR69_08985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR69_09015	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AYR69_09025	COG0753	catalase activity
AYR69_09040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYR69_09100	COG1535	isochorismatase
AYR69_09100	COG3433	isochorismatase activity
AYR69_09105	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_09110	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYR69_09115	COG4149	molybdate abc transporter
AYR69_09120	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYR69_09130	COG4638	Rieske (2fe-2S)
AYR69_09135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYR69_09140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR69_09140	COG0543	2 iron, 2 sulfur cluster binding
AYR69_09155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_09165	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_09170	COG0412	Dienelactone hydrolase
AYR69_09180	COG2207	Transcriptional regulator
AYR69_09195	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_09200	COG2610	gluconate transmembrane transporter activity
AYR69_09210	COG0583	DNA-binding transcription factor activity
AYR69_09220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR69_09225	COG2031	fatty acid transporter
AYR69_09230	COG0183	Belongs to the thiolase family
AYR69_09235	COG0583	DNA-binding transcription factor activity
AYR69_09240	COG0583	DNA-binding transcription factor activity
AYR69_09255	COG1027	Aspartate ammonia-lyase
AYR69_09265	COG0477	Major facilitator Superfamily
AYR69_09285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR69_09290	COG4521	taurine ABC transporter
AYR69_09315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYR69_09320	COG1733	regulation of RNA biosynthetic process
AYR69_09325	COG2207	Transcriptional regulator
AYR69_09325	COG3708	Transcriptional regulator
AYR69_09340	COG0730	response to heat
AYR69_09350	COG3453	Protein conserved in bacteria
AYR69_09350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR69_09360	COG3781	membrane
AYR69_09365	COG1063	alcohol dehydrogenase
AYR69_09375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR69_09380	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYR69_09385	COG0022	dehydrogenase e1 component
AYR69_09390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AYR69_09395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYR69_09410	COG3706	GGDEF domain
AYR69_09425	COG0133	tryptophan synthase activity
AYR69_09435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYR69_09470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYR69_09500	COG2226	methyltransferase
AYR69_09555	COG0842	Transport permease protein
AYR69_09560	COG0842	Transport permease protein
AYR69_09565	COG1131	(ABC) transporter
AYR69_09580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR69_09585	COG4773	Receptor
AYR69_09605	COG0730	response to heat
AYR69_09610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYR69_09630	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYR69_09645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR69_09685	COG4264	IucA IucC family
AYR69_09690	COG4264	IucA IucC family
AYR69_09710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYR69_09725	COG1960	acyl-CoA dehydrogenase activity
AYR69_09730	COG1960	acyl-CoA dehydrogenase activity
AYR69_09735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYR69_09740	COG2207	Transcriptional regulator
AYR69_09745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYR69_09750	COG0776	regulation of translation
AYR69_09775	COG0822	iron-sulfur transferase activity
AYR69_09780	COG0316	Belongs to the HesB IscA family
AYR69_09810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYR69_09840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYR69_09845	COG0702	epimerase
AYR69_09880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYR69_09890	COG0339	signal peptide processing
AYR69_09935	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYR69_09940	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYR69_09970	COG0776	regulation of translation
AYR69_09990	COG0590	tRNA wobble adenosine to inosine editing
AYR69_10020	COG2165	general secretion pathway protein
AYR69_10035	COG0084	hydrolase, TatD family'
AYR69_10055	COG1663	tetraacyldisaccharide 4'-kinase activity
AYR69_10060	COG1132	(ABC) transporter
AYR69_10070	COG0811	peptide transport
AYR69_10075	COG1475	DNA binding
AYR69_10080	COG1192	Involved in chromosome partitioning
AYR69_10090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYR69_10105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYR69_10110	COG0191	fructose-bisphosphate aldolase activity
AYR69_10130	COG0424	maF-like protein
AYR69_10135	COG2850	peptidyl-arginine hydroxylation
AYR69_10145	COG0640	Transcriptional regulator
AYR69_10155	COG3619	membrane
AYR69_10160	COG3122	Protein conserved in bacteria
AYR69_10165	COG1132	(ABC) transporter
AYR69_10185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYR69_10190	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYR69_10200	COG0506	proline dehydrogenase activity
AYR69_10200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYR69_10200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYR69_10205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AYR69_10220	COG3698	Phosphodiester glycosidase
AYR69_10230	COG2353	YceI-like domain
AYR69_10240	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYR69_10285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYR69_10285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYR69_10310	COG3539	Fimbrial protein
AYR69_10315	COG3121	Chaperone
AYR69_10340	COG0697	spore germination
AYR69_10350	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYR69_10360	COG0583	DNA-binding transcription factor activity
AYR69_10380	COG1309	transcriptional regulator
AYR69_10395	COG1522	sequence-specific DNA binding
AYR69_10405	COG1126	abc transporter atp-binding protein
AYR69_10410	COG0765	amino acid transport
AYR69_10415	COG0765	amino acid transport
AYR69_10445	COG1464	Belongs to the NlpA lipoprotein family
AYR69_10455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR69_10460	COG2011	ABC-type metal ion transport system permease component
AYR69_10465	COG0012	GTP binding
AYR69_10490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYR69_10530	COG0386	Belongs to the glutathione peroxidase family
AYR69_10540	COG0436	Aminotransferase
AYR69_10580	COG3634	alkyl hydroperoxide reductase activity
AYR69_10595	COG0583	DNA-binding transcription factor activity
AYR69_10600	COG0798	PFAM Bile acid sodium symporter
AYR69_10605	COG0640	Transcriptional regulator
AYR69_10620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AYR69_10630	COG0583	DNA-binding transcription factor activity
AYR69_10640	COG1953	Uracil, thiamine, allantoin
AYR69_10650	COG2175	clavaminate synthase activity
AYR69_10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR69_10660	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AYR69_10665	COG4521	taurine ABC transporter
AYR69_10675	COG0477	Major facilitator Superfamily
AYR69_10695	COG1271	oxidase subunit
AYR69_10700	COG1294	oxidase, subunit
AYR69_10710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR69_10730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYR69_10750	COG3052	prosthetic group binding
AYR69_10755	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AYR69_10765	COG2814	Major facilitator Superfamily
AYR69_10785	COG1346	cytolysis
AYR69_10795	COG0583	DNA-binding transcription factor activity
AYR69_10800	COG0625	glutathione transferase activity
AYR69_10805	COG0625	glutathione transferase activity
AYR69_10810	COG0583	DNA-binding transcription factor activity
AYR69_10825	COG1045	serine acetyltransferase
AYR69_10830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYR69_10835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYR69_10840	COG1280	lysine exporter protein (LysE YggA)
AYR69_10850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR69_10855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR69_10860	COG1126	abc transporter atp-binding protein
AYR69_10865	COG0765	amino acid transport
AYR69_10870	COG0765	amino acid transport
AYR69_10885	COG0784	Response regulator, receiver
AYR69_10885	COG2205	protein histidine kinase activity
AYR69_10905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYR69_10925	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_10975	COG0583	DNA-binding transcription factor activity
AYR69_10995	COG0318	PFAM AMP-dependent synthetase and ligase
AYR69_11000	COG1309	transcriptional regulator
AYR69_11005	COG1960	acyl-CoA dehydrogenase activity
AYR69_11010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYR69_11015	COG1024	Enoyl-CoA hydratase
AYR69_11030	COG0583	DNA-binding transcription factor activity
AYR69_11045	COG1960	acyl-CoA dehydrogenase activity
AYR69_11055	COG2814	Major facilitator Superfamily
AYR69_11065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR69_11070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR69_11075	COG2814	Major facilitator Superfamily
AYR69_11080	COG1960	acyl-CoA dehydrogenase activity
AYR69_11085	COG1024	Enoyl-CoA hydratase
AYR69_11090	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_11095	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR69_11100	COG0183	Belongs to the thiolase family
AYR69_11110	COG2814	Major facilitator Superfamily
AYR69_11120	COG1024	Enoyl-CoA hydratase
AYR69_11135	COG1960	acyl-CoA dehydrogenase activity
AYR69_11140	COG2814	Major facilitator Superfamily
AYR69_11145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR69_11150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AYR69_11165	COG3842	ATPase activity
AYR69_11170	COG1840	ABC-type Fe3 transport system, periplasmic component
AYR69_11180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR69_11185	COG1414	Transcriptional regulator
AYR69_11195	COG0583	DNA-binding transcription factor activity
AYR69_11200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYR69_11205	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_11215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYR69_11220	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_11225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR69_11230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_11235	COG2267	carboxylic ester hydrolase activity
AYR69_11255	COG3038	cytochrome b561
AYR69_11260	COG0753	catalase activity
AYR69_11295	COG2050	protein possibly involved in aromatic compounds catabolism
AYR69_11305	COG3327	negative regulation of DNA-templated transcription, initiation
AYR69_11310	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AYR69_11315	COG0183	Belongs to the thiolase family
AYR69_11320	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR69_11325	COG1024	Enoyl-CoA hydratase
AYR69_11330	COG1024	Enoyl-CoA hydratase
AYR69_11335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR69_11340	COG2151	metal-sulfur cluster biosynthetic enzyme
AYR69_11345	COG3396	Phenylacetate-CoA oxygenase
AYR69_11350	COG3460	Phenylacetate-CoA oxygenase
AYR69_11355	COG3396	Phenylacetate-CoA oxygenase
AYR69_11360	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_11360	COG2030	dehydratase
AYR69_11365	COG1760	l-serine dehydratase
AYR69_11370	COG0531	amino acid
AYR69_11375	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_11390	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR69_11400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR69_11420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR69_11430	COG0789	Transcriptional regulator
AYR69_11450	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYR69_11465	COG2807	transmembrane transport
AYR69_11470	COG0590	tRNA wobble adenosine to inosine editing
AYR69_11480	COG0583	DNA-binding transcription factor activity
AYR69_11535	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYR69_11535	COG2885	chlorophyll binding
AYR69_11600	COG1116	anion transmembrane transporter activity
AYR69_11605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR69_11615	COG0864	Transcriptional regulator
AYR69_11630	COG1733	regulation of RNA biosynthetic process
AYR69_11635	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR69_11640	COG0439	Biotin carboxylase
AYR69_11655	COG1063	alcohol dehydrogenase
AYR69_11665	COG1309	transcriptional regulator
AYR69_11690	COG0038	chloride channel
AYR69_11695	COG4770	biotin carboxylase activity
AYR69_11715	COG1914	H( )-stimulated, divalent metal cation uptake system
AYR69_11720	COG0583	DNA-binding transcription factor activity
AYR69_11735	COG3209	COG3209 Rhs family protein
AYR69_11740	COG3501	Rhs element vgr protein
AYR69_11765	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR69_11785	COG2814	Major facilitator Superfamily
AYR69_11800	COG1560	Kdo2-lipid A biosynthetic process
AYR69_11810	COG5006	permease, DMT superfamily
AYR69_11815	COG1522	sequence-specific DNA binding
AYR69_11830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYR69_11870	COG1538	Outer membrane efflux protein
AYR69_11875	COG1137	ATPase activity
AYR69_11880	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYR69_11890	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYR69_11895	COG0517	IMP dehydrogenase activity
AYR69_11895	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYR69_11930	COG1733	regulation of RNA biosynthetic process
AYR69_11935	COG2814	Major facilitator Superfamily
AYR69_11965	COG1278	Cold shock
AYR69_11970	COG1280	lysine exporter protein (LysE YggA)
AYR69_12015	COG1570	exodeoxyribonuclease VII activity
AYR69_12065	COG0583	DNA-binding transcription factor activity
AYR69_12070	COG4638	Rieske (2fe-2S)
AYR69_12075	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYR69_12080	COG0633	Ferredoxin
AYR69_12080	COG0543	2 iron, 2 sulfur cluster binding
AYR69_12085	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_12090	COG3135	benzoate transporter
AYR69_12095	COG2814	Major facilitator Superfamily
AYR69_12110	COG1643	Atp-dependent helicase
AYR69_12115	COG0450	alkyl hydroperoxide reductase
AYR69_12125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYR69_12135	COG3634	alkyl hydroperoxide reductase activity
AYR69_12155	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYR69_12160	COG0625	glutathione transferase activity
AYR69_12170	COG2885	chlorophyll binding
AYR69_12220	COG1765	OsmC-like protein
AYR69_12240	COG0667	Aldo Keto reductase
AYR69_12255	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYR69_12265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYR69_12285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYR69_12295	COG3038	cytochrome b561
AYR69_12300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AYR69_12305	COG2252	PERMEase
AYR69_12315	COG2072	flavoprotein involved in K transport
AYR69_12330	COG1741	Belongs to the pirin family
AYR69_12335	COG1309	transcriptional regulator
AYR69_12345	COG0300	oxidoreductase activity
AYR69_12355	COG3316	Transposase and inactivated derivatives
AYR69_12375	COG3316	Transposase and inactivated derivatives
AYR69_12400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYR69_12405	COG1610	YqeY-like protein
AYR69_12410	COG4783	chaperone-mediated protein folding
AYR69_12435	COG1286	toxin biosynthetic process
AYR69_12465	COG0778	Nitroreductase
AYR69_12475	COG0513	Belongs to the DEAD box helicase family
AYR69_12495	COG2363	Small membrane protein
AYR69_12525	COG1234	tRNA 3'-trailer cleavage
AYR69_12530	COG2195	Cleaves the N-terminal amino acid of tripeptides
AYR69_12540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYR69_12550	COG2819	hydrolase of the alpha beta superfamily
AYR69_12555	COG1960	acyl-CoA dehydrogenase activity
AYR69_12560	COG1301	dicarboxylic acid transport
AYR69_12565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYR69_12570	COG3139	Protein of unknown function (DUF1315)
AYR69_12575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYR69_12580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYR69_12590	COG0494	nUDIX hydrolase
AYR69_12600	COG0642	Histidine kinase
AYR69_12605	COG0745	RESPONSE REGULATOR receiver
AYR69_12625	COG1720	tRNA m6t6A37 methyltransferase activity
AYR69_12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR69_12650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYR69_12660	COG4598	ABC transporter
AYR69_12665	COG4160	amino acid transport
AYR69_12670	COG4215	(ABC) transporter
AYR69_12685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_12695	COG1538	Outer membrane efflux protein
AYR69_12745	COG1061	Type III restriction enzyme res subunit
AYR69_12780	COG1131	(ABC) transporter
AYR69_12785	COG0842	Transport permease protein
AYR69_12800	COG0772	Belongs to the SEDS family
AYR69_12805	COG2951	lytic endotransglycosylase activity
AYR69_12830	COG2207	Transcriptional regulator
AYR69_12845	COG0052	Belongs to the universal ribosomal protein uS2 family
AYR69_12850	COG0024	Methionine aminopeptidase
AYR69_12860	COG2223	nitrite transmembrane transporter activity
AYR69_12875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR69_12880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYR69_12885	COG1960	acyl-CoA dehydrogenase activity
AYR69_12900	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AYR69_12905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYR69_12910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYR69_12930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYR69_12935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYR69_12940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYR69_12975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYR69_12990	COG3104	oligopeptide transport
AYR69_13000	COG0512	Glutamine amidotransferase of anthranilate synthase
AYR69_13005	COG0308	aminopeptidase N
AYR69_13035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYR69_13075	COG3739	integral membrane protein
AYR69_13090	COG1169	isochorismate synthase
AYR69_13100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AYR69_13110	COG1132	(ABC) transporter
AYR69_13125	COG3433	isochorismatase activity
AYR69_13125	COG1535	isochorismatase
AYR69_13130	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYR69_13135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR69_13145	COG4774	siderophore transport
AYR69_13150	COG4607	ABC-type enterochelin transport system periplasmic component
AYR69_13155	COG4604	ABC transporter, ATP-binding protein
AYR69_13160	COG4605	iron ion homeostasis
AYR69_13165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYR69_13170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR69_13185	COG2964	Protein conserved in bacteria
AYR69_13195	COG1741	Belongs to the pirin family
AYR69_13210	COG1309	transcriptional regulator
AYR69_13220	COG4948	Mandelate Racemase Muconate Lactonizing
AYR69_13225	COG2814	Major facilitator Superfamily
AYR69_13260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR69_13260	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AYR69_13265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR69_13280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR69_13285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR69_13290	COG0583	DNA-binding transcription factor activity
AYR69_13295	COG1113	amino acid transport
AYR69_13315	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AYR69_13315	COG2508	Transcriptional regulator
AYR69_13345	COG2879	small protein
AYR69_13350	COG1966	Carbon starvation protein
AYR69_13395	COG1067	ATP-dependent peptidase activity
AYR69_13400	COG0583	DNA-binding transcription factor activity
AYR69_13425	COG1686	Belongs to the peptidase S11 family
AYR69_13430	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYR69_13465	COG0616	signal peptide processing
AYR69_13470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYR69_13480	COG0573	inorganic phosphate transmembrane transporter activity
AYR69_13485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYR69_13490	COG1113	amino acid transport
AYR69_13495	COG3961	Belongs to the TPP enzyme family
AYR69_13500	COG1522	sequence-specific DNA binding
AYR69_13510	COG0076	glutamate decarboxylase activity
AYR69_13515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYR69_13525	COG1309	transcriptional regulator
AYR69_13540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR69_13575	COG0352	thiamine-phosphate diphosphorylase activity
AYR69_13600	COG0612	Peptidase, M16
AYR69_13615	COG0583	DNA-binding transcription factor activity
AYR69_13620	COG0477	Major facilitator Superfamily
AYR69_13640	COG1187	pseudouridine synthase activity
AYR69_13655	COG1686	Belongs to the peptidase S11 family
AYR69_13660	COG1252	NADH dehydrogenase
AYR69_13670	COG0415	Belongs to the DNA photolyase family
AYR69_13685	COG1215	transferase activity, transferring glycosyl groups
AYR69_13715	COG2070	2-Nitropropane dioxygenase
AYR69_13770	COG0556	nucleotide-excision repair
AYR69_13815	COG4221	oxidoreductase activity
AYR69_13825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYR69_13830	COG1381	Involved in DNA repair and RecF pathway recombination
AYR69_13840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYR69_13855	COG0681	Belongs to the peptidase S26 family
AYR69_13870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYR69_13890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYR69_13895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYR69_13900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYR69_13910	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYR69_13915	COG4208	sulfate ABC transporter
AYR69_13920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYR69_13925	COG0583	DNA-binding transcription factor activity
AYR69_13930	COG4625	pathogenesis
AYR69_13945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYR69_13960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYR69_13970	COG1051	belongs to the nudix hydrolase family
AYR69_13970	COG1056	cytidyltransferase-related domain
AYR69_13975	COG1024	Enoyl-CoA hydratase
AYR69_13980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYR69_13990	COG2814	Major facilitator Superfamily
AYR69_13995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYR69_13995	COG0047	phosphoribosylformylglycinamidine synthase activity
AYR69_14015	COG1473	amidohydrolase
AYR69_14020	COG0824	Thioesterase
AYR69_14040	COG0823	Involved in the tonB-independent uptake of proteins
AYR69_14060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR69_14105	COG0628	permease
AYR69_14115	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYR69_14120	COG0596	Alpha beta hydrolase
AYR69_14125	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYR69_14125	COG0616	signal peptide processing
AYR69_14135	COG2333	competence protein COMEC
AYR69_14135	COG0658	competence protein
AYR69_14140	COG1136	(ABC) transporter
AYR69_14145	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYR69_14175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_14195	COG0463	Glycosyl transferase, family 2
AYR69_14225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYR69_14230	COG1280	lysine exporter protein (LysE YggA)
AYR69_14240	COG0019	diaminopimelate decarboxylase activity
AYR69_14250	COG1113	amino acid transport
AYR69_14265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AYR69_14275	COG3339	Conserved Protein
AYR69_14280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AYR69_14285	COG0243	molybdopterin cofactor binding
AYR69_14290	COG1929	Belongs to the glycerate kinase type-1 family
AYR69_14305	COG0778	Nitroreductase
AYR69_14340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR69_14355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYR69_14375	COG0741	lytic transglycosylase activity
AYR69_14395	COG0584	glycerophosphoryl diester phosphodiesterase
AYR69_14400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR69_14420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYR69_14440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYR69_14445	COG0477	Major facilitator Superfamily
AYR69_14495	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYR69_14500	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYR69_14525	COG0505	Belongs to the CarA family
AYR69_14545	COG0589	response to stress
AYR69_14560	COG2843	Capsule synthesis protein
AYR69_14595	COG2321	neutral zinc metallopeptidase
AYR69_14600	COG2354	Protein conserved in bacteria
AYR69_14620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR69_14635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYR69_14640	COG1053	succinate dehydrogenase
AYR69_14645	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYR69_14650	COG2009	succinate dehydrogenase
AYR69_14685	COG2921	Belongs to the UPF0250 family
AYR69_14690	COG0321	lipoyl(octanoyl) transferase activity
AYR69_14705	COG0531	amino acid
AYR69_14715	COG1733	regulation of RNA biosynthetic process
AYR69_14720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYR69_14725	COG1648	precorrin-2 dehydrogenase activity
AYR69_14725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYR69_14740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AYR69_14770	COG0671	phosphoesterase, PA-phosphatase related
AYR69_14775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_14785	COG1538	Outer membrane efflux protein
AYR69_14790	COG0393	Putative heavy-metal-binding
AYR69_14795	COG0393	Putative heavy-metal-binding
AYR69_14805	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_14815	COG0525	valine-tRNA ligase activity
AYR69_14835	COG0583	DNA-binding transcription factor activity
AYR69_14840	COG0004	ammonium transporteR
AYR69_14850	COG0642	Histidine kinase
AYR69_14855	COG0745	RESPONSE REGULATOR receiver
AYR69_14860	COG2194	sulfuric ester hydrolase activity
AYR69_14880	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYR69_14895	COG2315	Protein conserved in bacteria
AYR69_14900	COG0142	geranyltranstransferase activity
AYR69_14905	COG2828	Protein conserved in bacteria
AYR69_14910	COG1113	amino acid transport
AYR69_14930	COG2207	Transcriptional regulator
AYR69_14955	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR69_14975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR69_14985	COG1530	ribonuclease E activity
AYR69_14990	COG0424	maF-like protein
AYR69_14995	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYR69_15000	COG1792	Involved in formation and maintenance of cell shape
AYR69_15005	COG1077	Cell shape determining protein MreB Mrl
AYR69_15010	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR69_15020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR69_15045	COG3590	peptidase
AYR69_15050	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYR69_15055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYR69_15060	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYR69_15065	COG1115	amino acid carrier protein
AYR69_15080	COG2814	Major facilitator Superfamily
AYR69_15085	COG1289	transmembrane transporter activity
AYR69_15135	COG1376	ErfK ybiS ycfS ynhG family protein
AYR69_15140	COG2832	Protein of unknown function (DUF454)
AYR69_15150	COG5510	response to toxic substance
AYR69_15170	COG0840	transmembrane signaling receptor activity
AYR69_15215	COG2824	Alkylphosphonate utilization operon protein PhnA
AYR69_15220	COG3189	MarR family transcriptional regulator
AYR69_15230	COG0354	folic acid binding
AYR69_15235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR69_15250	COG1902	pentaerythritol trinitrate reductase activity
AYR69_15260	COG2094	Belongs to the DNA glycosylase MPG family
AYR69_15290	COG2233	PERMEase
AYR69_15300	COG0833	amino acid
AYR69_15305	COG1690	Belongs to the RtcB family
AYR69_15315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYR69_15315	COG2885	chlorophyll binding
AYR69_15325	COG0183	Belongs to the thiolase family
AYR69_15345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR69_15365	COG2207	Transcriptional regulator
AYR69_15370	COG0183	Belongs to the thiolase family
AYR69_15400	COG1272	protein, Hemolysin III
AYR69_15405	COG0477	Major facilitator Superfamily
AYR69_15420	COG0450	alkyl hydroperoxide reductase
AYR69_15440	COG0285	dihydrofolate synthase activity
AYR69_15475	COG0133	tryptophan synthase activity
AYR69_15490	COG2096	Adenosyltransferase
AYR69_15510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYR69_15515	COG0745	RESPONSE REGULATOR receiver
AYR69_15520	COG2205	protein histidine kinase activity
AYR69_15530	COG1960	acyl-CoA dehydrogenase activity
AYR69_15535	COG1960	acyl-CoA dehydrogenase activity
AYR69_15585	COG1442	glycosyl transferase family 8
AYR69_15600	COG0438	transferase activity, transferring glycosyl groups
AYR69_15610	COG0438	transferase activity, transferring glycosyl groups
AYR69_15615	COG0726	polysaccharide deacetylase
AYR69_15630	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYR69_15635	COG2205	protein histidine kinase activity
AYR69_15665	COG1862	Preprotein translocase
AYR69_15675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYR69_15680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYR69_15690	COG3781	membrane
AYR69_15695	COG0613	PHP domain protein
AYR69_15705	COG2350	Protein conserved in bacteria
AYR69_15735	COG1607	acyl-coa hydrolase
AYR69_15750	COG3453	Protein conserved in bacteria
AYR69_15750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR69_15815	COG2199	diguanylate cyclase activity
AYR69_15825	COG1408	metallophosphoesterase
AYR69_15830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYR69_15840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYR69_15860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYR69_15865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYR69_15880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AYR69_15890	COG2969	positive regulation of protein catabolic process
AYR69_15910	COG1960	acyl-CoA dehydrogenase activity
AYR69_15915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYR69_15930	COG1309	transcriptional regulator
AYR69_15935	COG1960	acyl-CoA dehydrogenase activity
AYR69_15980	COG1183	phosphatidylcholine synthase activity
AYR69_15985	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYR69_16015	COG0741	lytic transglycosylase activity
AYR69_16015	COG1196	nuclear chromosome segregation
AYR69_16015	COG0739	heme binding
AYR69_16025	COG1702	phosphate starvation-inducible protein PhoH
AYR69_16060	COG1295	ribonuclease BN
AYR69_16065	COG0697	spore germination
AYR69_16070	COG2169	Transcriptional regulator
AYR69_16075	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYR69_16120	COG0557	exoribonuclease II activity
AYR69_16125	COG0339	signal peptide processing
AYR69_16130	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYR69_16160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYR69_16165	COG1960	acyl-CoA dehydrogenase activity
AYR69_16190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYR69_16200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AYR69_16320	COG0626	cystathionine gamma-synthase activity
AYR69_16325	COG0433	COG0433 Predicted ATPase
AYR69_16330	COG1017	nitric oxide dioxygenase activity
AYR69_16330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR69_16335	COG1959	2 iron, 2 sulfur cluster binding
AYR69_16350	COG1301	dicarboxylic acid transport
AYR69_16355	COG1946	Acyl-CoA thioesterase
AYR69_16375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYR69_16380	COG1040	competence protein
AYR69_16385	COG0494	nUDIX hydrolase
AYR69_16395	COG0598	Magnesium transport protein CorA
AYR69_16405	COG2854	intermembrane phospholipid transfer
AYR69_16415	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYR69_16420	COG1127	ABC transporter
AYR69_16430	COG0513	Belongs to the DEAD box helicase family
AYR69_16450	COG0408	coproporphyrinogen oxidase activity
AYR69_16465	COG1960	acyl-CoA dehydrogenase activity
AYR69_16475	COG1983	PspC domain protein
AYR69_16480	COG0517	IMP dehydrogenase activity
AYR69_16515	COG1106	Psort location Cytoplasmic, score
AYR69_16535	COG0583	DNA-binding transcription factor activity
AYR69_16575	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_16585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYR69_16590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYR69_16595	COG0833	amino acid
AYR69_16625	COG1192	Involved in chromosome partitioning
AYR69_16630	COG0628	permease
AYR69_16640	COG1289	transmembrane transporter activity
AYR69_16655	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR69_16660	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYR69_16670	COG0277	FAD linked oxidase domain protein
AYR69_16675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYR69_16700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYR69_16705	COG5380	lipid catabolic process
AYR69_16735	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYR69_16785	COG0194	GDP metabolic process
AYR69_16795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYR69_16815	COG3307	-O-antigen
AYR69_16835	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYR69_16840	COG1704	LemA family
AYR69_16850	COG0493	'glutamate synthase
AYR69_16855	COG0067	glutamate synthase
AYR69_16855	COG0069	glutamate synthase activity
AYR69_16855	COG0070	glutamate synthase
AYR69_16905	COG2226	methyltransferase
AYR69_16920	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYR69_16925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYR69_16970	COG0833	amino acid
AYR69_17065	COG0488	(ABC) transporter
AYR69_17075	COG4221	oxidoreductase activity
AYR69_17080	COG0659	secondary active sulfate transmembrane transporter activity
AYR69_17090	COG0745	RESPONSE REGULATOR receiver
AYR69_17100	COG0427	acetyl-CoA hydrolase
AYR69_17130	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYR69_17170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYR69_17250	COG1733	regulation of RNA biosynthetic process
AYR69_17280	COG0667	Aldo Keto reductase
AYR69_17300	COG0583	DNA-binding transcription factor activity
AYR69_17305	COG2814	Major facilitator Superfamily
AYR69_17335	COG1335	isochorismatase
AYR69_17345	COG1012	belongs to the aldehyde dehydrogenase family
AYR69_17350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYR69_17360	COG1113	amino acid transport
AYR69_17370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYR69_17385	COG2814	Major facilitator Superfamily
AYR69_17395	COG0351	phosphomethylpyrimidine kinase
AYR69_17395	COG0352	thiamine-phosphate diphosphorylase activity
AYR69_17395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYR69_17415	COG1309	transcriptional regulator
AYR69_17420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYR69_17425	COG3706	GGDEF domain
AYR69_17435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR69_17445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYR69_17450	COG3162	membrane
AYR69_17455	COG2205	protein histidine kinase activity
AYR69_17455	COG2198	Histidine kinase
AYR69_17455	COG0784	Response regulator, receiver
AYR69_17480	COG1522	sequence-specific DNA binding
AYR69_17485	COG1335	isochorismatase
AYR69_17490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR69_17500	COG0668	transmembrane transport
AYR69_17505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYR69_17510	COG1519	Transferase
AYR69_17515	COG1902	pentaerythritol trinitrate reductase activity
AYR69_17535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYR69_17560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR69_17560	COG0426	domain, Protein
AYR69_17570	COG2119	membrane
AYR69_17580	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYR69_17590	COG4942	peptidase
AYR69_17605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYR69_17615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYR69_17635	COG0189	ligase activity
AYR69_17660	COG0708	Exodeoxyribonuclease III
AYR69_17665	COG1393	Belongs to the ArsC family
AYR69_17680	COG3706	GGDEF domain
AYR69_17715	COG2351	hydroxyisourate hydrolase activity
AYR69_17720	COG2233	PERMEase
AYR69_17730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR69_17740	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYR69_17745	COG1028	Short-chain dehydrogenase reductase Sdr
AYR69_17755	COG3150	esterase
AYR69_17815	COG2918	glutathione biosynthetic process
AYR69_17830	COG2733	membrane
AYR69_17835	COG0436	Aminotransferase
AYR69_17840	COG0534	Mate efflux family protein
AYR69_17925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYR69_17930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYR69_17940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AYR69_17985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYR69_17990	COG0546	phosphoglycolate phosphatase activity
AYR69_18000	COG0010	Belongs to the arginase family
AYR69_18030	COG2188	Transcriptional regulator
AYR69_18040	COG0523	cobalamin synthesis protein
AYR69_18050	COG1113	amino acid transport
AYR69_18060	COG0625	glutathione transferase activity
AYR69_18080	COG1683	Conserved Protein
AYR69_18085	COG0534	Mate efflux family protein
AYR69_18090	COG0385	Bile acid
AYR69_18095	COG1335	isochorismatase
AYR69_18100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR69_18120	COG2116	formate transmembrane transporter activity
AYR69_18125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYR69_18130	COG2133	pyrroloquinoline quinone binding
AYR69_18135	COG2983	Belongs to the UPF0260 family
AYR69_18155	COG1194	a g-specific adenine glycosylase
AYR69_18170	COG2818	Glycosylase
AYR69_18175	COG1064	alcohol dehydrogenase
AYR69_18180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR69_18190	COG0583	DNA-binding transcription factor activity
AYR69_18200	COG2814	Major facilitator Superfamily
AYR69_18235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR69_18260	COG2233	PERMEase
AYR69_18265	COG0583	DNA-binding transcription factor activity
AYR69_18300	COG0733	neurotransmitter:sodium symporter activity
AYR69_18340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYR69_18365	COG0583	DNA-binding transcription factor activity
AYR69_18395	COG2951	lytic endotransglycosylase activity
AYR69_18400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYR69_18420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYR69_18430	COG0671	phosphoesterase, PA-phosphatase related
AYR69_18435	COG0861	Integral membrane protein TerC family
AYR69_18445	COG0754	glutathionylspermidine amidase activity
AYR69_18455	COG0402	S-adenosylhomocysteine deaminase activity
AYR69_18475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR69_18480	COG1230	cation diffusion facilitator family transporter
AYR69_18495	COG0706	membrane insertase activity
AYR69_18510	COG0230	Belongs to the bacterial ribosomal protein bL34 family