locus-tag	class	description
AYR68_00010	COG0592	DNA-directed DNA polymerase activity
AYR68_00020	COG0187	DNA topoisomerase II activity
AYR68_00030	COG0586	Pfam SNARE associated Golgi protein
AYR68_00035	COG0488	(ABC) transporter
AYR68_00060	COG0596	Alpha beta hydrolase
AYR68_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYR68_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYR68_00110	COG0733	neurotransmitter:sodium symporter activity
AYR68_00150	COG2233	PERMEase
AYR68_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_00200	COG2814	Major facilitator Superfamily
AYR68_00205	COG0656	L-ascorbic acid biosynthetic process
AYR68_00210	COG0583	DNA-binding transcription factor activity
AYR68_00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR68_00225	COG1064	alcohol dehydrogenase
AYR68_00230	COG2818	Glycosylase
AYR68_00245	COG1194	a g-specific adenine glycosylase
AYR68_00275	COG2983	Belongs to the UPF0260 family
AYR68_00280	COG2133	pyrroloquinoline quinone binding
AYR68_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYR68_00290	COG2116	formate transmembrane transporter activity
AYR68_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR68_00315	COG1335	isochorismatase
AYR68_00320	COG0385	Bile acid
AYR68_00325	COG0534	Mate efflux family protein
AYR68_00330	COG1683	Conserved Protein
AYR68_00350	COG0625	glutathione transferase activity
AYR68_00360	COG1113	amino acid transport
AYR68_00370	COG0523	cobalamin synthesis protein
AYR68_00380	COG2188	Transcriptional regulator
AYR68_00410	COG0010	Belongs to the arginase family
AYR68_00445	COG0589	response to stress
AYR68_00450	COG0659	secondary active sulfate transmembrane transporter activity
AYR68_00510	COG0347	Belongs to the P(II) protein family
AYR68_00515	COG0004	ammonium transporteR
AYR68_00525	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR68_00525	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYR68_00565	COG0795	lipopolysaccharide-transporting ATPase activity
AYR68_00570	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYR68_00575	COG0793	Belongs to the peptidase S41A family
AYR68_00590	COG2197	response regulator
AYR68_00600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYR68_00610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR68_00615	COG4974	Belongs to the 'phage' integrase family
AYR68_00640	COG0772	Belongs to the SEDS family
AYR68_00645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYR68_00650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYR68_00655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYR68_00680	COG0697	spore germination
AYR68_00685	COG1538	Outer membrane efflux protein
AYR68_00705	COG3275	phosphorelay sensor kinase activity
AYR68_00715	COG0181	hydroxymethylbilane synthase activity
AYR68_00760	COG1716	ATPase activity
AYR68_00765	COG0546	phosphoglycolate phosphatase activity
AYR68_00860	COG0596	Alpha beta hydrolase
AYR68_00865	COG2056	Na+-H+ antiporter family
AYR68_00880	COG0326	Molecular chaperone. Has ATPase activity
AYR68_00895	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AYR68_00960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYR68_00965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYR68_00965	COG2169	Transcriptional regulator
AYR68_00995	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYR68_01005	COG0497	DNA recombination
AYR68_01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR68_01030	COG0237	dephospho-CoA kinase activity
AYR68_01080	COG0195	Participates in both transcription termination and antitermination
AYR68_01100	COG2212	antiporter activity
AYR68_01110	COG0651	ATP synthesis coupled electron transport
AYR68_01115	COG1006	Multisubunit Na H antiporter MnhC subunit
AYR68_01120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYR68_01120	COG2111	Na H antiporter
AYR68_01135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYR68_01140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR68_01155	COG2226	methyltransferase
AYR68_01175	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AYR68_01180	COG1074	ATP-dependent DNA helicase activity
AYR68_01185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYR68_01205	COG0598	Magnesium transport protein CorA
AYR68_01210	COG0789	Transcriptional regulator
AYR68_01215	COG0484	heat shock protein binding
AYR68_01225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYR68_01230	COG0475	glutathione-regulated potassium exporter activity
AYR68_01230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR68_01235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYR68_01255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR68_01265	COG4535	Mg2 and Co2 transporter CorC
AYR68_01270	COG0425	Belongs to the sulfur carrier protein TusA family
AYR68_01275	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AYR68_01275	COG0644	oxidoreductase
AYR68_01285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYR68_01300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR68_01305	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AYR68_01345	COG4372	Transposase
AYR68_01370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYR68_01385	COG0534	Mate efflux family protein
AYR68_01395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYR68_01400	COG4221	oxidoreductase activity
AYR68_01405	COG0583	DNA-binding transcription factor activity
AYR68_01425	COG1530	ribonuclease E activity
AYR68_01435	COG0546	phosphoglycolate phosphatase activity
AYR68_01440	COG2378	regulation of single-species biofilm formation
AYR68_01445	COG0625	glutathione transferase activity
AYR68_01455	COG0583	DNA-binding transcription factor activity
AYR68_01520	COG0473	3-isopropylmalate dehydrogenase activity
AYR68_01575	COG1301	dicarboxylic acid transport
AYR68_01585	COG1560	Kdo2-lipid A biosynthetic process
AYR68_01590	COG1280	lysine exporter protein (LysE YggA)
AYR68_01610	COG1733	regulation of RNA biosynthetic process
AYR68_01635	COG0210	DNA helicase
AYR68_01640	COG0724	RNA recognition motif
AYR68_01660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR68_01660	COG4651	solute:proton antiporter activity
AYR68_01665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYR68_01670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AYR68_01685	COG0788	formyltetrahydrofolate deformylase activity
AYR68_01785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR68_01785	COG2813	Specifically methylates the guanine in position
AYR68_01795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYR68_01805	COG4774	siderophore transport
AYR68_01815	COG0740	serine-type endopeptidase activity
AYR68_01835	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AYR68_01835	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AYR68_01840	COG0857	belongs to the CobB CobQ family
AYR68_01840	COG0280	phosphate acetyltransferase
AYR68_01845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AYR68_01855	COG0800	Aldolase
AYR68_01865	COG3265	gluconokinase activity
AYR68_01870	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_01880	COG2267	carboxylic ester hydrolase activity
AYR68_01895	COG0793	Belongs to the peptidase S41A family
AYR68_01930	COG1426	Protein conserved in bacteria
AYR68_01970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR68_01975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR68_01985	COG0318	PFAM AMP-dependent synthetase and ligase
AYR68_02000	COG2986	histidine ammonia-lyase
AYR68_02040	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_02045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AYR68_02065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYR68_02075	COG1162	GTPase activity
AYR68_02080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AYR68_02095	COG1538	Outer membrane efflux protein
AYR68_02100	COG1136	(ABC) transporter
AYR68_02100	COG0577	efflux transmembrane transporter activity
AYR68_02105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_02130	COG0028	Belongs to the TPP enzyme family
AYR68_02135	COG0440	acetolactate synthase activity
AYR68_02165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYR68_02180	COG0084	hydrolase, TatD family'
AYR68_02195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYR68_02200	COG0583	DNA-binding transcription factor activity
AYR68_02210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYR68_02215	COG2814	Major facilitator Superfamily
AYR68_02225	COG0697	spore germination
AYR68_02230	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYR68_02235	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AYR68_02240	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AYR68_02255	COG3622	Belongs to the hyi family
AYR68_02260	COG2084	Dehydrogenase
AYR68_02265	COG1024	Enoyl-CoA hydratase
AYR68_02270	COG5002	protein histidine kinase activity
AYR68_02270	COG2205	protein histidine kinase activity
AYR68_02270	COG0784	Response regulator, receiver
AYR68_02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYR68_02300	COG3956	TIGRFAM MazG family protein
AYR68_02305	COG1555	photosystem II stabilization
AYR68_02310	COG0617	tRNA 3'-terminal CCA addition
AYR68_02315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYR68_02335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR68_02340	COG3028	Belongs to the UPF0307 family
AYR68_02345	COG0318	PFAM AMP-dependent synthetase and ligase
AYR68_02360	COG0625	glutathione transferase activity
AYR68_02365	COG1238	metal cluster binding
AYR68_02380	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYR68_02405	COG0072	phenylalanine-tRNA ligase activity
AYR68_02430	COG0248	Ppx GppA phosphatase
AYR68_02440	COG0037	tRNA processing
AYR68_02495	COG1764	response to oxidative stress
AYR68_02500	COG1846	Transcriptional regulator
AYR68_02510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYR68_02570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYR68_02575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AYR68_02580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYR68_02590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYR68_02645	COG1214	PFAM Peptidase M22, glycoprotease
AYR68_02670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYR68_02675	COG0561	phosphatase activity
AYR68_02685	COG2132	Multicopper oxidase
AYR68_02690	COG3667	copper resistance
AYR68_02705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYR68_02710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYR68_02715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AYR68_02745	COG1063	alcohol dehydrogenase
AYR68_02750	COG0583	DNA-binding transcription factor activity
AYR68_02755	COG1960	acyl-CoA dehydrogenase activity
AYR68_02760	COG2814	Major facilitator Superfamily
AYR68_02765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AYR68_02775	COG1053	succinate dehydrogenase
AYR68_02780	COG0583	DNA-binding transcription factor activity
AYR68_02795	COG0583	DNA-binding transcription factor activity
AYR68_02805	COG1473	amidohydrolase
AYR68_02825	COG0583	DNA-binding transcription factor activity
AYR68_02835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AYR68_02840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_02870	COG0384	phenazine biosynthesis protein PhzF
AYR68_02890	COG4993	Dehydrogenase
AYR68_02960	COG2205	protein histidine kinase activity
AYR68_02970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYR68_02990	COG0745	RESPONSE REGULATOR receiver
AYR68_02995	COG2205	protein histidine kinase activity
AYR68_03030	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYR68_03060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYR68_03065	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYR68_03085	COG0583	DNA-binding transcription factor activity
AYR68_03105	COG0668	transmembrane transport
AYR68_03115	COG2081	HI0933 family
AYR68_03120	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AYR68_03150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR68_03150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYR68_03160	COG0489	protein tyrosine kinase activity
AYR68_03210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYR68_03220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYR68_03235	COG0730	response to heat
AYR68_03245	COG1196	nuclear chromosome segregation
AYR68_03265	COG2223	nitrite transmembrane transporter activity
AYR68_03270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AYR68_03275	COG1877	trehalose-phosphatase activity
AYR68_03280	COG2226	methyltransferase
AYR68_03280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR68_03280	COG0596	Alpha beta hydrolase
AYR68_03295	COG4106	trans-aconitate 2-methyltransferase activity
AYR68_03310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AYR68_03315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AYR68_03320	COG0009	L-threonylcarbamoyladenylate synthase
AYR68_03325	COG3101	peptidyl-lysine hydroxylation
AYR68_03330	COG1399	metal-binding, possibly nucleic acid-binding protein
AYR68_03355	COG1652	LysM domain
AYR68_03360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYR68_03360	COG0351	phosphomethylpyrimidine kinase
AYR68_03360	COG0352	thiamine-phosphate diphosphorylase activity
AYR68_03370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AYR68_03400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR68_03430	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AYR68_03445	COG0358	DNA primase activity
AYR68_03455	COG0564	pseudouridine synthase activity
AYR68_03480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYR68_03500	COG0583	DNA-binding transcription factor activity
AYR68_03505	COG0473	3-isopropylmalate dehydrogenase activity
AYR68_03525	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_03545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AYR68_03545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AYR68_03605	COG0456	acetyltransferase
AYR68_03615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYR68_03620	COG0492	ferredoxin-NADP+ reductase activity
AYR68_03625	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AYR68_03625	COG1674	ftsk spoiiie
AYR68_03630	COG1280	lysine exporter protein (LysE YggA)
AYR68_03650	COG4372	Transposase
AYR68_03655	COG4372	Transposase
AYR68_03680	COG2894	cell division
AYR68_03695	COG0204	Acyl-transferase
AYR68_03700	COG2885	chlorophyll binding
AYR68_03705	COG0210	DNA helicase
AYR68_03715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR68_03730	COG0121	glutamine amidotransferase
AYR68_03750	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYR68_03755	COG0735	belongs to the Fur family
AYR68_03780	COG0420	3'-5' exonuclease activity
AYR68_03800	COG1090	epimerase
AYR68_03815	COG2050	protein possibly involved in aromatic compounds catabolism
AYR68_03825	COG2814	Major facilitator Superfamily
AYR68_03830	COG0405	Gamma-glutamyltransferase
AYR68_03895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR68_03985	COG1484	DNA-dependent DNA replication
AYR68_04030	COG3755	Protein conserved in bacteria
AYR68_04175	COG2026	Addiction module toxin, RelE StbE family
AYR68_04215	COG0592	DNA-directed DNA polymerase activity
AYR68_04345	COG0477	Major facilitator Superfamily
AYR68_04350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR68_04375	COG0531	amino acid
AYR68_04380	COG2040	homocysteine
AYR68_04405	COG1309	transcriptional regulator
AYR68_04410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR68_04415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR68_04425	COG1607	acyl-coa hydrolase
AYR68_04435	COG0523	cobalamin synthesis protein
AYR68_04445	COG4681	YaeQ
AYR68_04455	COG1649	PFAM Uncharacterised BCR, COG1649
AYR68_04455	COG0726	polysaccharide deacetylase
AYR68_04460	COG1215	transferase activity, transferring glycosyl groups
AYR68_04470	COG1024	Enoyl-CoA hydratase
AYR68_04485	COG1414	Transcriptional regulator
AYR68_04505	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_04515	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR68_04520	COG2271	Major facilitator Superfamily
AYR68_04530	COG2267	carboxylic ester hydrolase activity
AYR68_04535	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_04550	COG0028	Belongs to the TPP enzyme family
AYR68_04560	COG0477	Major facilitator Superfamily
AYR68_04565	COG0242	peptide deformylase activity
AYR68_04570	COG2066	Belongs to the glutaminase family
AYR68_04575	COG2207	Transcriptional regulator
AYR68_04580	COG2223	nitrite transmembrane transporter activity
AYR68_04595	COG0583	DNA-binding transcription factor activity
AYR68_04600	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_04605	COG2271	Major facilitator Superfamily
AYR68_04610	COG3959	Transketolase, thiamine diphosphate binding domain
AYR68_04615	COG3958	Transketolase
AYR68_04625	COG0306	phosphate transporter
AYR68_04645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AYR68_04690	COG4181	ATPase activity
AYR68_04695	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYR68_04720	COG0583	DNA-binding transcription factor activity
AYR68_04730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR68_04735	COG1773	rubredoxin
AYR68_04780	COG2851	Citrate transporter
AYR68_04790	COG1253	flavin adenine dinucleotide binding
AYR68_04830	COG0804	urea catabolic process
AYR68_04840	COG0830	nickel cation binding
AYR68_04855	COG0742	ribosomal rna small subunit methyltransferase
AYR68_04860	COG0768	penicillin binding
AYR68_04880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYR68_04885	COG2878	Part of a membrane complex involved in electron transport
AYR68_04890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYR68_04900	COG3384	dioxygenase
AYR68_04935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYR68_05100	COG5410	chromosome segregation
AYR68_05170	COG1061	Type III restriction enzyme res subunit
AYR68_05180	COG1192	Involved in chromosome partitioning
AYR68_05185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYR68_05195	COG1061	Type III restriction enzyme res subunit
AYR68_05330	COG2194	sulfuric ester hydrolase activity
AYR68_05365	COG0006	proline dipeptidase activity
AYR68_05370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR68_05375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR68_05395	COG1279	arginine transmembrane transporter activity
AYR68_05400	COG0583	DNA-binding transcription factor activity
AYR68_05450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR68_05455	COG1388	LysM domain
AYR68_05455	COG0741	lytic transglycosylase activity
AYR68_05455	COG1388	LysM domain
AYR68_05455	COG0741	lytic transglycosylase activity
AYR68_05465	COG4174	ABC transporter (Permease)
AYR68_05470	COG4239	(ABC) transporter, permease
AYR68_05475	COG4172	Belongs to the ABC transporter superfamily
AYR68_05495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYR68_05505	COG2203	Gaf domain
AYR68_05505	COG4251	negative regulation of phosphorylation
AYR68_05505	COG5001	Diguanylate cyclase
AYR68_05505	COG3706	GGDEF domain
AYR68_05515	COG1902	pentaerythritol trinitrate reductase activity
AYR68_05515	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR68_05530	COG4269	membrane
AYR68_05550	COG3501	Rhs element vgr protein
AYR68_05560	COG4372	Transposase
AYR68_05615	COG1113	amino acid transport
AYR68_05625	COG0531	amino acid
AYR68_05645	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_05665	COG1113	amino acid transport
AYR68_05670	COG3316	Transposase and inactivated derivatives
AYR68_05685	COG3316	Transposase and inactivated derivatives
AYR68_05700	COG2072	flavoprotein involved in K transport
AYR68_05710	COG2252	PERMEase
AYR68_05715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AYR68_05720	COG3038	cytochrome b561
AYR68_05730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYR68_05750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYR68_05760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYR68_05775	COG0667	Aldo Keto reductase
AYR68_05785	COG1765	OsmC-like protein
AYR68_05835	COG2885	chlorophyll binding
AYR68_05845	COG0625	glutathione transferase activity
AYR68_05850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYR68_05870	COG3634	alkyl hydroperoxide reductase activity
AYR68_05880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYR68_05890	COG0450	alkyl hydroperoxide reductase
AYR68_05895	COG1643	Atp-dependent helicase
AYR68_05910	COG2814	Major facilitator Superfamily
AYR68_05915	COG3135	benzoate transporter
AYR68_05920	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_05925	COG0543	2 iron, 2 sulfur cluster binding
AYR68_05925	COG0633	Ferredoxin
AYR68_05930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYR68_05935	COG4638	Rieske (2fe-2S)
AYR68_05940	COG0583	DNA-binding transcription factor activity
AYR68_05990	COG1570	exodeoxyribonuclease VII activity
AYR68_06035	COG1280	lysine exporter protein (LysE YggA)
AYR68_06040	COG1278	Cold shock
AYR68_06070	COG2814	Major facilitator Superfamily
AYR68_06075	COG1733	regulation of RNA biosynthetic process
AYR68_06110	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYR68_06110	COG0517	IMP dehydrogenase activity
AYR68_06115	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AYR68_06125	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYR68_06130	COG1137	ATPase activity
AYR68_06135	COG1538	Outer membrane efflux protein
AYR68_06175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AYR68_06190	COG1522	sequence-specific DNA binding
AYR68_06195	COG5006	permease, DMT superfamily
AYR68_06205	COG1560	Kdo2-lipid A biosynthetic process
AYR68_06215	COG2814	Major facilitator Superfamily
AYR68_06235	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR68_06260	COG3501	Rhs element vgr protein
AYR68_06265	COG3209	COG3209 Rhs family protein
AYR68_06280	COG0583	DNA-binding transcription factor activity
AYR68_06285	COG1914	H( )-stimulated, divalent metal cation uptake system
AYR68_06305	COG4770	biotin carboxylase activity
AYR68_06310	COG0038	chloride channel
AYR68_06335	COG1309	transcriptional regulator
AYR68_06345	COG1063	alcohol dehydrogenase
AYR68_06360	COG0439	Biotin carboxylase
AYR68_06365	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR68_06370	COG1733	regulation of RNA biosynthetic process
AYR68_06385	COG0864	Transcriptional regulator
AYR68_06395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR68_06400	COG1116	anion transmembrane transporter activity
AYR68_06465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYR68_06465	COG2885	chlorophyll binding
AYR68_06505	COG0583	DNA-binding transcription factor activity
AYR68_06515	COG0590	tRNA wobble adenosine to inosine editing
AYR68_06520	COG2807	transmembrane transport
AYR68_06535	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AYR68_06555	COG0789	Transcriptional regulator
AYR68_06565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR68_06585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR68_06600	COG3316	Transposase and inactivated derivatives
AYR68_06620	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_06625	COG0531	amino acid
AYR68_06630	COG1760	l-serine dehydratase
AYR68_06635	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_06635	COG2030	dehydratase
AYR68_06640	COG3396	Phenylacetate-CoA oxygenase
AYR68_06645	COG3460	Phenylacetate-CoA oxygenase
AYR68_06650	COG3396	Phenylacetate-CoA oxygenase
AYR68_06655	COG2151	metal-sulfur cluster biosynthetic enzyme
AYR68_06660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR68_06665	COG1024	Enoyl-CoA hydratase
AYR68_06670	COG1024	Enoyl-CoA hydratase
AYR68_06675	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR68_06680	COG0183	Belongs to the thiolase family
AYR68_06685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AYR68_06690	COG3327	negative regulation of DNA-templated transcription, initiation
AYR68_06700	COG2050	protein possibly involved in aromatic compounds catabolism
AYR68_06735	COG0753	catalase activity
AYR68_06740	COG3038	cytochrome b561
AYR68_06770	COG2267	carboxylic ester hydrolase activity
AYR68_06775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_06780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR68_06785	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_06790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYR68_06800	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_06805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYR68_06810	COG0583	DNA-binding transcription factor activity
AYR68_06820	COG1414	Transcriptional regulator
AYR68_06825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR68_06835	COG1840	ABC-type Fe3 transport system, periplasmic component
AYR68_06840	COG3842	ATPase activity
AYR68_06855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AYR68_06860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR68_06865	COG2814	Major facilitator Superfamily
AYR68_06870	COG1960	acyl-CoA dehydrogenase activity
AYR68_06885	COG1024	Enoyl-CoA hydratase
AYR68_06895	COG2814	Major facilitator Superfamily
AYR68_06905	COG0183	Belongs to the thiolase family
AYR68_06910	COG1250	3-hydroxyacyl-CoA dehydrogenase
AYR68_06915	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_06920	COG1024	Enoyl-CoA hydratase
AYR68_06925	COG1960	acyl-CoA dehydrogenase activity
AYR68_06930	COG2814	Major facilitator Superfamily
AYR68_06935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR68_06940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR68_06950	COG2814	Major facilitator Superfamily
AYR68_06960	COG1960	acyl-CoA dehydrogenase activity
AYR68_06975	COG0583	DNA-binding transcription factor activity
AYR68_06990	COG1024	Enoyl-CoA hydratase
AYR68_06995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYR68_07000	COG1960	acyl-CoA dehydrogenase activity
AYR68_07005	COG1309	transcriptional regulator
AYR68_07010	COG0318	PFAM AMP-dependent synthetase and ligase
AYR68_07030	COG0583	DNA-binding transcription factor activity
AYR68_07080	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_07100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYR68_07120	COG2205	protein histidine kinase activity
AYR68_07120	COG0784	Response regulator, receiver
AYR68_07135	COG0765	amino acid transport
AYR68_07140	COG0765	amino acid transport
AYR68_07145	COG1126	abc transporter atp-binding protein
AYR68_07155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYR68_07165	COG1280	lysine exporter protein (LysE YggA)
AYR68_07170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYR68_07175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYR68_07180	COG1045	serine acetyltransferase
AYR68_07195	COG0583	DNA-binding transcription factor activity
AYR68_07200	COG0625	glutathione transferase activity
AYR68_07205	COG0625	glutathione transferase activity
AYR68_07210	COG0583	DNA-binding transcription factor activity
AYR68_07220	COG1346	cytolysis
AYR68_07240	COG2814	Major facilitator Superfamily
AYR68_07250	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AYR68_07255	COG3052	prosthetic group binding
AYR68_07275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYR68_07295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR68_07305	COG1294	oxidase, subunit
AYR68_07310	COG1271	oxidase subunit
AYR68_07330	COG0477	Major facilitator Superfamily
AYR68_07335	COG3316	Transposase and inactivated derivatives
AYR68_07345	COG3316	Transposase and inactivated derivatives
AYR68_07375	COG1132	(ABC) transporter
AYR68_07440	COG3173	Aminoglycoside phosphotransferase
AYR68_07450	COG2433	Pfam Transposase IS66
AYR68_07495	COG5001	Diguanylate cyclase
AYR68_07495	COG3300	MHYT domain
AYR68_07515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AYR68_07515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR68_07515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AYR68_07520	COG1105	Belongs to the carbohydrate kinase PfkB family
AYR68_07525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AYR68_07525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYR68_07555	COG0024	Methionine aminopeptidase
AYR68_07560	COG0583	DNA-binding transcription factor activity
AYR68_07570	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYR68_07575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYR68_07580	COG0516	GMP reductase activity
AYR68_07580	COG0517	IMP dehydrogenase activity
AYR68_07605	COG0552	protein localization to endoplasmic reticulum
AYR68_07615	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AYR68_07630	COG4890	Cyd operon protein YbgT
AYR68_07635	COG1294	oxidase, subunit
AYR68_07650	COG1585	Membrane protein implicated in regulation of membrane protease activity
AYR68_07660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYR68_07665	COG4774	siderophore transport
AYR68_07680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYR68_07685	COG0569	domain protein
AYR68_07690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYR68_07720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYR68_07725	COG0542	response to heat
AYR68_07735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYR68_07750	COG1902	pentaerythritol trinitrate reductase activity
AYR68_07750	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR68_07795	COG2323	membrane
AYR68_07800	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AYR68_07810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR68_07815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR68_07820	COG0183	Belongs to the thiolase family
AYR68_07825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AYR68_07830	COG0596	Alpha beta hydrolase
AYR68_07835	COG2271	Major facilitator Superfamily
AYR68_07840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYR68_07845	COG3485	protocatechuate 3,4-dioxygenase
AYR68_07850	COG3485	protocatechuate 3,4-dioxygenase
AYR68_07855	COG0710	3-dehydroquinate dehydratase activity
AYR68_07860	COG3420	alginic acid biosynthetic process
AYR68_07865	COG3659	wide pore channel activity
AYR68_07870	COG4993	Dehydrogenase
AYR68_07880	COG2391	methyltransferase activity
AYR68_07895	COG1414	Transcriptional regulator
AYR68_07900	COG0583	DNA-binding transcription factor activity
AYR68_07905	COG1960	acyl-CoA dehydrogenase activity
AYR68_07930	COG2814	Major facilitator Superfamily
AYR68_07940	COG0154	amidase activity
AYR68_07960	COG4638	Rieske (2fe-2S)
AYR68_07970	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_07980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_07990	COG3733	amine oxidase
AYR68_08000	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_08010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYR68_08015	COG0183	Belongs to the thiolase family
AYR68_08020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR68_08025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AYR68_08035	COG4829	muconolactone delta-isomerase
AYR68_08040	COG4948	Mandelate Racemase Muconate Lactonizing
AYR68_08045	COG0583	DNA-binding transcription factor activity
AYR68_08055	COG2186	Transcriptional regulator
AYR68_08075	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_08095	COG1960	acyl-CoA dehydrogenase activity
AYR68_08100	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_08105	COG3829	transcription factor binding
AYR68_08115	COG3162	membrane
AYR68_08130	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_08145	COG0753	catalase activity
AYR68_08170	COG1846	Transcriptional regulator
AYR68_08175	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYR68_08175	COG1902	pentaerythritol trinitrate reductase activity
AYR68_08185	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AYR68_08215	COG1309	transcriptional regulator
AYR68_08225	COG1335	isochorismatase
AYR68_08230	COG0583	DNA-binding transcription factor activity
AYR68_08240	COG0475	glutathione-regulated potassium exporter activity
AYR68_08240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYR68_08250	COG1473	amidohydrolase
AYR68_08260	COG2831	hemolysin activation secretion protein
AYR68_08265	COG3210	domain, Protein
AYR68_08310	COG0583	DNA-binding transcription factor activity
AYR68_08335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYR68_08340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYR68_08375	COG4372	Transposase
AYR68_08395	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_08400	COG0129	dihydroxy-acid dehydratase activity
AYR68_08410	COG0583	DNA-binding transcription factor activity
AYR68_08415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYR68_08425	COG2084	Dehydrogenase
AYR68_08430	COG2207	Transcriptional regulator
AYR68_08445	COG1064	alcohol dehydrogenase
AYR68_08460	COG1120	ATPase activity
AYR68_08480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYR68_08595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYR68_08645	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_08670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_08675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYR68_08680	COG1538	Outer membrane efflux protein
AYR68_08690	COG2072	flavoprotein involved in K transport
AYR68_08710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR68_08730	COG3539	Fimbrial protein
AYR68_08765	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AYR68_08775	COG0753	catalase activity
AYR68_08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYR68_08850	COG1535	isochorismatase
AYR68_08850	COG3433	isochorismatase activity
AYR68_08855	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_08860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYR68_08865	COG4149	molybdate abc transporter
AYR68_08870	COG0725	ABC transporter, periplasmic molybdate-binding protein
AYR68_08880	COG4638	Rieske (2fe-2S)
AYR68_08885	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AYR68_08890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR68_08890	COG0543	2 iron, 2 sulfur cluster binding
AYR68_08905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_08915	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_08920	COG0412	Dienelactone hydrolase
AYR68_08930	COG2207	Transcriptional regulator
AYR68_08945	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_08950	COG2610	gluconate transmembrane transporter activity
AYR68_08960	COG0583	DNA-binding transcription factor activity
AYR68_08970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AYR68_08975	COG2031	fatty acid transporter
AYR68_08980	COG0183	Belongs to the thiolase family
AYR68_08985	COG0583	DNA-binding transcription factor activity
AYR68_08990	COG0583	DNA-binding transcription factor activity
AYR68_09005	COG1027	Aspartate ammonia-lyase
AYR68_09015	COG0477	Major facilitator Superfamily
AYR68_09035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR68_09040	COG4521	taurine ABC transporter
AYR68_09065	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYR68_09070	COG1733	regulation of RNA biosynthetic process
AYR68_09075	COG3708	Transcriptional regulator
AYR68_09075	COG2207	Transcriptional regulator
AYR68_09090	COG0730	response to heat
AYR68_09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR68_09100	COG3453	Protein conserved in bacteria
AYR68_09110	COG3781	membrane
AYR68_09115	COG1063	alcohol dehydrogenase
AYR68_09125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR68_09130	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYR68_09135	COG0022	dehydrogenase e1 component
AYR68_09140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AYR68_09145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYR68_09160	COG3706	GGDEF domain
AYR68_09175	COG0133	tryptophan synthase activity
AYR68_09185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYR68_09220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYR68_09245	COG2226	methyltransferase
AYR68_09300	COG0842	Transport permease protein
AYR68_09305	COG0842	Transport permease protein
AYR68_09310	COG1131	(ABC) transporter
AYR68_09325	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR68_09330	COG4773	Receptor
AYR68_09350	COG0730	response to heat
AYR68_09355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYR68_09375	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AYR68_09390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYR68_09430	COG4264	IucA IucC family
AYR68_09435	COG4264	IucA IucC family
AYR68_09455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AYR68_09470	COG1960	acyl-CoA dehydrogenase activity
AYR68_09475	COG1960	acyl-CoA dehydrogenase activity
AYR68_09480	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYR68_09485	COG2207	Transcriptional regulator
AYR68_09490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYR68_09495	COG0776	regulation of translation
AYR68_09520	COG0822	iron-sulfur transferase activity
AYR68_09525	COG0316	Belongs to the HesB IscA family
AYR68_09555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYR68_09575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AYR68_09580	COG0702	epimerase
AYR68_09615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYR68_09625	COG0339	signal peptide processing
AYR68_09670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AYR68_09675	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AYR68_09705	COG0776	regulation of translation
AYR68_09725	COG0590	tRNA wobble adenosine to inosine editing
AYR68_09755	COG2165	general secretion pathway protein
AYR68_09770	COG0084	hydrolase, TatD family'
AYR68_09790	COG1663	tetraacyldisaccharide 4'-kinase activity
AYR68_09795	COG1132	(ABC) transporter
AYR68_09805	COG0811	peptide transport
AYR68_09810	COG1475	DNA binding
AYR68_09815	COG1192	Involved in chromosome partitioning
AYR68_09825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYR68_09840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYR68_09845	COG0191	fructose-bisphosphate aldolase activity
AYR68_09865	COG0424	maF-like protein
AYR68_09870	COG2850	peptidyl-arginine hydroxylation
AYR68_09880	COG0640	Transcriptional regulator
AYR68_09890	COG3619	membrane
AYR68_09895	COG3122	Protein conserved in bacteria
AYR68_09900	COG1132	(ABC) transporter
AYR68_09920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AYR68_09925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYR68_09935	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYR68_09935	COG0506	proline dehydrogenase activity
AYR68_09935	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AYR68_09940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AYR68_09955	COG3698	Phosphodiester glycosidase
AYR68_09965	COG2353	YceI-like domain
AYR68_09975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYR68_10020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYR68_10020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYR68_10045	COG3539	Fimbrial protein
AYR68_10050	COG3121	Chaperone
AYR68_10075	COG0697	spore germination
AYR68_10085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AYR68_10095	COG0583	DNA-binding transcription factor activity
AYR68_10130	COG1309	transcriptional regulator
AYR68_10145	COG1522	sequence-specific DNA binding
AYR68_10155	COG1126	abc transporter atp-binding protein
AYR68_10160	COG0765	amino acid transport
AYR68_10165	COG0765	amino acid transport
AYR68_10195	COG1464	Belongs to the NlpA lipoprotein family
AYR68_10205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR68_10210	COG2011	ABC-type metal ion transport system permease component
AYR68_10215	COG0012	GTP binding
AYR68_10240	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYR68_10280	COG0386	Belongs to the glutathione peroxidase family
AYR68_10290	COG0436	Aminotransferase
AYR68_10330	COG3634	alkyl hydroperoxide reductase activity
AYR68_10345	COG0583	DNA-binding transcription factor activity
AYR68_10355	COG3316	Transposase and inactivated derivatives
AYR68_10380	COG4372	Transposase
AYR68_10400	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AYR68_10410	COG2137	regulation of response to DNA damage stimulus
AYR68_10425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR68_10460	COG0575	Belongs to the CDS family
AYR68_10465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AYR68_10500	COG3852	Histidine kinase
AYR68_10505	COG2204	response regulator
AYR68_10570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYR68_10575	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AYR68_10595	COG0697	spore germination
AYR68_10600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR68_10610	COG0303	'Molybdopterin
AYR68_10615	COG0315	cyclic pyranopterin monophosphate synthase activity
AYR68_10615	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYR68_10630	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AYR68_10635	COG0243	molybdopterin cofactor binding
AYR68_10645	COG0243	molybdopterin cofactor binding
AYR68_10650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR68_10655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR68_10655	COG2146	nitrite reductase [NAD(P)H] activity
AYR68_10665	COG0745	RESPONSE REGULATOR receiver
AYR68_10670	COG1116	anion transmembrane transporter activity
AYR68_10670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR68_10685	COG0511	ligase activity, forming carbon-carbon bonds
AYR68_10700	COG2814	Major facilitator Superfamily
AYR68_10740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYR68_10750	COG1454	alcohol dehydrogenase
AYR68_10755	COG0824	Thioesterase
AYR68_10765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYR68_10795	COG0183	Belongs to the thiolase family
AYR68_10805	COG0583	DNA-binding transcription factor activity
AYR68_10820	COG1522	sequence-specific DNA binding
AYR68_10825	COG3135	benzoate transporter
AYR68_10835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYR68_10855	COG0589	response to stress
AYR68_10860	COG0488	(ABC) transporter
AYR68_10880	COG4773	Receptor
AYR68_10910	COG0668	transmembrane transport
AYR68_10920	COG1309	transcriptional regulator
AYR68_10935	COG1605	Chorismate mutase
AYR68_10945	COG4221	oxidoreductase activity
AYR68_10955	COG0308	aminopeptidase N
AYR68_10975	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYR68_10985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AYR68_10990	COG1454	alcohol dehydrogenase
AYR68_11010	COG0531	amino acid
AYR68_11015	COG4303	Ethanolamine ammonia lyase large subunit
AYR68_11020	COG4302	ethanolamine ammonia-lyase activity
AYR68_11025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYR68_11025	COG0519	Catalyzes the synthesis of GMP from XMP
AYR68_11040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYR68_11055	COG0697	spore germination
AYR68_11060	COG1923	regulation of RNA biosynthetic process
AYR68_11070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYR68_11075	COG0802	atpase or kinase
AYR68_11095	COG1187	pseudouridine synthase activity
AYR68_11110	COG0583	DNA-binding transcription factor activity
AYR68_11125	COG2814	Major facilitator Superfamily
AYR68_11130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AYR68_11155	COG0729	surface antigen
AYR68_11175	COG0174	glutamine synthetase
AYR68_11180	COG0745	RESPONSE REGULATOR receiver
AYR68_11185	COG2205	protein histidine kinase activity
AYR68_11195	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AYR68_11200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AYR68_11225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_11230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR68_11235	COG1960	acyl-CoA dehydrogenase activity
AYR68_11265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR68_11270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR68_11290	COG0583	DNA-binding transcription factor activity
AYR68_11305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR68_11315	COG3658	cytochrome
AYR68_11320	COG1215	transferase activity, transferring glycosyl groups
AYR68_11325	COG1649	PFAM Uncharacterised BCR, COG1649
AYR68_11325	COG0726	polysaccharide deacetylase
AYR68_11350	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AYR68_11355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AYR68_11365	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AYR68_11390	COG0305	Participates in initiation and elongation during chromosome replication
AYR68_11395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AYR68_11405	COG1305	Transglutaminase-like
AYR68_11415	COG2308	Evidence 4 Homologs of previously reported genes of
AYR68_11445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AYR68_11450	COG0138	bifunctional purine biosynthesis protein purh
AYR68_11455	COG0151	Belongs to the GarS family
AYR68_11460	COG1464	Belongs to the NlpA lipoprotein family
AYR68_11465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AYR68_11470	COG2011	ABC-type metal ion transport system permease component
AYR68_11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR68_11485	COG1301	dicarboxylic acid transport
AYR68_11515	COG1794	racemase activity, acting on amino acids and derivatives
AYR68_11525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYR68_11525	COG3008	intermembrane lipid transfer
AYR68_11530	COG2995	paraquat-inducible protein a
AYR68_11540	COG2985	domain, Protein
AYR68_11565	COG0477	Major facilitator Superfamily
AYR68_11615	COG2186	Transcriptional regulator
AYR68_11625	COG0786	glutamate:sodium symporter activity
AYR68_11630	COG3243	poly(R)-hydroxyalkanoic acid synthase
AYR68_11655	COG3111	PFAM Bacterial OB fold (BOF) protein
AYR68_11750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AYR68_11755	COG1610	YqeY-like protein
AYR68_11760	COG4783	chaperone-mediated protein folding
AYR68_11785	COG1286	toxin biosynthetic process
AYR68_11815	COG0778	Nitroreductase
AYR68_11825	COG0513	Belongs to the DEAD box helicase family
AYR68_11845	COG2363	Small membrane protein
AYR68_11875	COG1234	tRNA 3'-trailer cleavage
AYR68_11880	COG2195	Cleaves the N-terminal amino acid of tripeptides
AYR68_11890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYR68_11900	COG2819	hydrolase of the alpha beta superfamily
AYR68_11905	COG1960	acyl-CoA dehydrogenase activity
AYR68_11910	COG1301	dicarboxylic acid transport
AYR68_11915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYR68_11920	COG3139	Protein of unknown function (DUF1315)
AYR68_11925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYR68_11930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AYR68_11940	COG0494	nUDIX hydrolase
AYR68_11950	COG0642	Histidine kinase
AYR68_11955	COG0745	RESPONSE REGULATOR receiver
AYR68_11975	COG1720	tRNA m6t6A37 methyltransferase activity
AYR68_11990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR68_12000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYR68_12010	COG4598	ABC transporter
AYR68_12015	COG4160	amino acid transport
AYR68_12020	COG4215	(ABC) transporter
AYR68_12055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_12065	COG1538	Outer membrane efflux protein
AYR68_12100	COG1131	(ABC) transporter
AYR68_12105	COG0842	Transport permease protein
AYR68_12120	COG0772	Belongs to the SEDS family
AYR68_12125	COG2951	lytic endotransglycosylase activity
AYR68_12150	COG2207	Transcriptional regulator
AYR68_12165	COG0052	Belongs to the universal ribosomal protein uS2 family
AYR68_12170	COG0024	Methionine aminopeptidase
AYR68_12180	COG2223	nitrite transmembrane transporter activity
AYR68_12195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR68_12200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYR68_12205	COG1960	acyl-CoA dehydrogenase activity
AYR68_12220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AYR68_12225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYR68_12230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYR68_12250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYR68_12255	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYR68_12260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AYR68_12295	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYR68_12310	COG3104	oligopeptide transport
AYR68_12320	COG0512	Glutamine amidotransferase of anthranilate synthase
AYR68_12355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AYR68_12385	COG3739	integral membrane protein
AYR68_12400	COG1169	isochorismate synthase
AYR68_12410	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AYR68_12420	COG1132	(ABC) transporter
AYR68_12435	COG1535	isochorismatase
AYR68_12435	COG3433	isochorismatase activity
AYR68_12440	COG1021	2,3-dihydroxybenzoate-AMP ligase
AYR68_12445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR68_12455	COG4774	siderophore transport
AYR68_12460	COG4607	ABC-type enterochelin transport system periplasmic component
AYR68_12465	COG4604	ABC transporter, ATP-binding protein
AYR68_12470	COG4605	iron ion homeostasis
AYR68_12475	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYR68_12480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR68_12495	COG2964	Protein conserved in bacteria
AYR68_12505	COG1741	Belongs to the pirin family
AYR68_12520	COG1309	transcriptional regulator
AYR68_12530	COG4948	Mandelate Racemase Muconate Lactonizing
AYR68_12535	COG2814	Major facilitator Superfamily
AYR68_12570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYR68_12570	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AYR68_12575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR68_12590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR68_12595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR68_12600	COG0583	DNA-binding transcription factor activity
AYR68_12620	COG4372	Transposase
AYR68_12645	COG2508	Transcriptional regulator
AYR68_12645	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AYR68_12675	COG2879	small protein
AYR68_12680	COG1966	Carbon starvation protein
AYR68_12725	COG1067	ATP-dependent peptidase activity
AYR68_12730	COG0583	DNA-binding transcription factor activity
AYR68_12755	COG1686	Belongs to the peptidase S11 family
AYR68_12760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYR68_12795	COG0616	signal peptide processing
AYR68_12800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYR68_12810	COG0573	inorganic phosphate transmembrane transporter activity
AYR68_12815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYR68_12820	COG1113	amino acid transport
AYR68_12825	COG3961	Belongs to the TPP enzyme family
AYR68_12830	COG1522	sequence-specific DNA binding
AYR68_12840	COG0076	glutamate decarboxylase activity
AYR68_12845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYR68_12855	COG1309	transcriptional regulator
AYR68_12870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR68_12905	COG0352	thiamine-phosphate diphosphorylase activity
AYR68_12930	COG0612	Peptidase, M16
AYR68_12945	COG0583	DNA-binding transcription factor activity
AYR68_12950	COG0477	Major facilitator Superfamily
AYR68_12970	COG1187	pseudouridine synthase activity
AYR68_12985	COG1686	Belongs to the peptidase S11 family
AYR68_12990	COG1252	NADH dehydrogenase
AYR68_13000	COG0415	Belongs to the DNA photolyase family
AYR68_13015	COG1215	transferase activity, transferring glycosyl groups
AYR68_13045	COG2070	2-Nitropropane dioxygenase
AYR68_13235	COG5410	chromosome segregation
AYR68_13430	COG0556	nucleotide-excision repair
AYR68_13475	COG4221	oxidoreductase activity
AYR68_13485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYR68_13490	COG1381	Involved in DNA repair and RecF pathway recombination
AYR68_13500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYR68_13515	COG0681	Belongs to the peptidase S26 family
AYR68_13530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYR68_13550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYR68_13555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AYR68_13560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AYR68_13570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYR68_13575	COG4208	sulfate ABC transporter
AYR68_13580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AYR68_13585	COG0583	DNA-binding transcription factor activity
AYR68_13590	COG4625	pathogenesis
AYR68_13605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYR68_13620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYR68_13630	COG1051	belongs to the nudix hydrolase family
AYR68_13630	COG1056	cytidyltransferase-related domain
AYR68_13635	COG1024	Enoyl-CoA hydratase
AYR68_13640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYR68_13650	COG2814	Major facilitator Superfamily
AYR68_13655	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYR68_13655	COG0047	phosphoribosylformylglycinamidine synthase activity
AYR68_13675	COG1473	amidohydrolase
AYR68_13680	COG0824	Thioesterase
AYR68_13700	COG0823	Involved in the tonB-independent uptake of proteins
AYR68_13720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYR68_13755	COG0628	permease
AYR68_13765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYR68_13770	COG0596	Alpha beta hydrolase
AYR68_13775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AYR68_13775	COG0616	signal peptide processing
AYR68_13785	COG0658	competence protein
AYR68_13785	COG2333	competence protein COMEC
AYR68_13790	COG1136	(ABC) transporter
AYR68_13795	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYR68_13825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_13845	COG0463	Glycosyl transferase, family 2
AYR68_13890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYR68_13895	COG1280	lysine exporter protein (LysE YggA)
AYR68_13905	COG0019	diaminopimelate decarboxylase activity
AYR68_13915	COG1113	amino acid transport
AYR68_13930	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AYR68_13940	COG3339	Conserved Protein
AYR68_13945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AYR68_13950	COG0243	molybdopterin cofactor binding
AYR68_13955	COG1929	Belongs to the glycerate kinase type-1 family
AYR68_13970	COG0778	Nitroreductase
AYR68_13995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR68_14010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYR68_14030	COG0741	lytic transglycosylase activity
AYR68_14050	COG0584	glycerophosphoryl diester phosphodiesterase
AYR68_14055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR68_14080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AYR68_14100	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AYR68_14105	COG0477	Major facilitator Superfamily
AYR68_14155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYR68_14160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYR68_14185	COG0505	Belongs to the CarA family
AYR68_14205	COG0589	response to stress
AYR68_14220	COG2843	Capsule synthesis protein
AYR68_14245	COG2321	neutral zinc metallopeptidase
AYR68_14250	COG2354	Protein conserved in bacteria
AYR68_14270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYR68_14285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AYR68_14290	COG1053	succinate dehydrogenase
AYR68_14295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AYR68_14300	COG2009	succinate dehydrogenase
AYR68_14340	COG2921	Belongs to the UPF0250 family
AYR68_14345	COG0321	lipoyl(octanoyl) transferase activity
AYR68_14360	COG0531	amino acid
AYR68_14370	COG1733	regulation of RNA biosynthetic process
AYR68_14375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYR68_14380	COG1648	precorrin-2 dehydrogenase activity
AYR68_14380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AYR68_14395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AYR68_14425	COG0671	phosphoesterase, PA-phosphatase related
AYR68_14430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYR68_14440	COG1538	Outer membrane efflux protein
AYR68_14445	COG0393	Putative heavy-metal-binding
AYR68_14450	COG0393	Putative heavy-metal-binding
AYR68_14460	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_14470	COG0525	valine-tRNA ligase activity
AYR68_14490	COG0583	DNA-binding transcription factor activity
AYR68_14495	COG0004	ammonium transporteR
AYR68_14505	COG0642	Histidine kinase
AYR68_14510	COG0745	RESPONSE REGULATOR receiver
AYR68_14515	COG2194	sulfuric ester hydrolase activity
AYR68_14555	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYR68_14570	COG2315	Protein conserved in bacteria
AYR68_14575	COG0142	geranyltranstransferase activity
AYR68_14580	COG2828	Protein conserved in bacteria
AYR68_14585	COG1113	amino acid transport
AYR68_14605	COG2207	Transcriptional regulator
AYR68_14630	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR68_14650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR68_14660	COG1530	ribonuclease E activity
AYR68_14665	COG0424	maF-like protein
AYR68_14670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AYR68_14675	COG1792	Involved in formation and maintenance of cell shape
AYR68_14680	COG1077	Cell shape determining protein MreB Mrl
AYR68_14685	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR68_14695	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYR68_14725	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AYR68_14730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AYR68_14735	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYR68_14740	COG1115	amino acid carrier protein
AYR68_14755	COG2814	Major facilitator Superfamily
AYR68_14760	COG1289	transmembrane transporter activity
AYR68_14810	COG1376	ErfK ybiS ycfS ynhG family protein
AYR68_14815	COG2832	Protein of unknown function (DUF454)
AYR68_14825	COG5510	response to toxic substance
AYR68_14845	COG0840	transmembrane signaling receptor activity
AYR68_14885	COG3422	double-strand break repair
AYR68_14890	COG2824	Alkylphosphonate utilization operon protein PhnA
AYR68_14895	COG3189	MarR family transcriptional regulator
AYR68_14905	COG0354	folic acid binding
AYR68_14910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR68_14920	COG0679	Auxin Efflux Carrier
AYR68_14925	COG1902	pentaerythritol trinitrate reductase activity
AYR68_14930	COG4772	TonB-dependent receptor
AYR68_14935	COG2094	Belongs to the DNA glycosylase MPG family
AYR68_14965	COG2233	PERMEase
AYR68_14975	COG0833	amino acid
AYR68_14980	COG1690	Belongs to the RtcB family
AYR68_14990	COG2885	chlorophyll binding
AYR68_14990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AYR68_15000	COG0183	Belongs to the thiolase family
AYR68_15020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYR68_15040	COG2207	Transcriptional regulator
AYR68_15045	COG0183	Belongs to the thiolase family
AYR68_15075	COG1272	protein, Hemolysin III
AYR68_15080	COG0477	Major facilitator Superfamily
AYR68_15095	COG0450	alkyl hydroperoxide reductase
AYR68_15115	COG0285	dihydrofolate synthase activity
AYR68_15150	COG0133	tryptophan synthase activity
AYR68_15165	COG2096	Adenosyltransferase
AYR68_15185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYR68_15190	COG0745	RESPONSE REGULATOR receiver
AYR68_15195	COG2205	protein histidine kinase activity
AYR68_15205	COG1960	acyl-CoA dehydrogenase activity
AYR68_15210	COG1960	acyl-CoA dehydrogenase activity
AYR68_15215	COG0583	DNA-binding transcription factor activity
AYR68_15220	COG0625	glutathione transferase activity
AYR68_15285	COG0438	transferase activity, transferring glycosyl groups
AYR68_15290	COG0463	Glycosyl transferase, family 2
AYR68_15295	COG0726	polysaccharide deacetylase
AYR68_15315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYR68_15320	COG2205	protein histidine kinase activity
AYR68_15365	COG1862	Preprotein translocase
AYR68_15375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYR68_15380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYR68_15390	COG3781	membrane
AYR68_15395	COG0613	PHP domain protein
AYR68_15405	COG2350	Protein conserved in bacteria
AYR68_15435	COG1607	acyl-coa hydrolase
AYR68_15450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYR68_15450	COG3453	Protein conserved in bacteria
AYR68_15495	COG2199	diguanylate cyclase activity
AYR68_15505	COG1408	metallophosphoesterase
AYR68_15510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYR68_15520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYR68_15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYR68_15545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYR68_15560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AYR68_15570	COG2969	positive regulation of protein catabolic process
AYR68_15590	COG1960	acyl-CoA dehydrogenase activity
AYR68_15595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AYR68_15610	COG1309	transcriptional regulator
AYR68_15615	COG1960	acyl-CoA dehydrogenase activity
AYR68_15660	COG1183	phosphatidylcholine synthase activity
AYR68_15665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYR68_15695	COG1196	nuclear chromosome segregation
AYR68_15695	COG0741	lytic transglycosylase activity
AYR68_15695	COG0739	heme binding
AYR68_15705	COG1702	phosphate starvation-inducible protein PhoH
AYR68_15740	COG1295	ribonuclease BN
AYR68_15745	COG0697	spore germination
AYR68_15750	COG2169	Transcriptional regulator
AYR68_15755	COG0179	Fumarylacetoacetate (FAA) hydrolase
AYR68_15800	COG0557	exoribonuclease II activity
AYR68_15805	COG0339	signal peptide processing
AYR68_15810	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AYR68_15840	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AYR68_15845	COG1960	acyl-CoA dehydrogenase activity
AYR68_15870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYR68_15880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AYR68_16000	COG0626	cystathionine gamma-synthase activity
AYR68_16005	COG0433	COG0433 Predicted ATPase
AYR68_16010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYR68_16010	COG1017	nitric oxide dioxygenase activity
AYR68_16015	COG1959	2 iron, 2 sulfur cluster binding
AYR68_16030	COG1301	dicarboxylic acid transport
AYR68_16035	COG1946	Acyl-CoA thioesterase
AYR68_16055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYR68_16060	COG1040	competence protein
AYR68_16065	COG0494	nUDIX hydrolase
AYR68_16075	COG0598	Magnesium transport protein CorA
AYR68_16085	COG2854	intermembrane phospholipid transfer
AYR68_16095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYR68_16100	COG1127	ABC transporter
AYR68_16110	COG0513	Belongs to the DEAD box helicase family
AYR68_16130	COG0408	coproporphyrinogen oxidase activity
AYR68_16145	COG1960	acyl-CoA dehydrogenase activity
AYR68_16155	COG1983	PspC domain protein
AYR68_16160	COG0517	IMP dehydrogenase activity
AYR68_16205	COG0583	DNA-binding transcription factor activity
AYR68_16245	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_16255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYR68_16260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYR68_16265	COG0833	amino acid
AYR68_16295	COG1192	Involved in chromosome partitioning
AYR68_16300	COG0628	permease
AYR68_16310	COG1289	transmembrane transporter activity
AYR68_16325	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR68_16330	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AYR68_16340	COG0277	FAD linked oxidase domain protein
AYR68_16345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYR68_16385	COG1061	Type III restriction enzyme res subunit
AYR68_16395	COG1192	Involved in chromosome partitioning
AYR68_16400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AYR68_16410	COG1061	Type III restriction enzyme res subunit
AYR68_16430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYR68_16435	COG5380	lipid catabolic process
AYR68_16455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYR68_16505	COG0194	GDP metabolic process
AYR68_16515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYR68_16535	COG3307	-O-antigen
AYR68_16550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AYR68_16555	COG1704	LemA family
AYR68_16565	COG0493	'glutamate synthase
AYR68_16570	COG0069	glutamate synthase activity
AYR68_16570	COG0070	glutamate synthase
AYR68_16570	COG0067	glutamate synthase
AYR68_16620	COG2226	methyltransferase
AYR68_16635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYR68_16640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYR68_16685	COG0833	amino acid
AYR68_16765	COG0488	(ABC) transporter
AYR68_16775	COG4221	oxidoreductase activity
AYR68_16780	COG0659	secondary active sulfate transmembrane transporter activity
AYR68_16790	COG0745	RESPONSE REGULATOR receiver
AYR68_16800	COG0427	acetyl-CoA hydrolase
AYR68_16830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYR68_16860	COG2329	Antibiotic biosynthesis monooxygenase
AYR68_16875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYR68_16940	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYR68_16945	COG1733	regulation of RNA biosynthetic process
AYR68_16975	COG0667	Aldo Keto reductase
AYR68_16995	COG0583	DNA-binding transcription factor activity
AYR68_17000	COG2814	Major facilitator Superfamily
AYR68_17030	COG1335	isochorismatase
AYR68_17040	COG1012	belongs to the aldehyde dehydrogenase family
AYR68_17045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYR68_17055	COG1113	amino acid transport
AYR68_17065	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AYR68_17080	COG2814	Major facilitator Superfamily
AYR68_17090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AYR68_17090	COG0352	thiamine-phosphate diphosphorylase activity
AYR68_17090	COG0351	phosphomethylpyrimidine kinase
AYR68_17110	COG1309	transcriptional regulator
AYR68_17115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AYR68_17125	COG3706	GGDEF domain
AYR68_17135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYR68_17145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYR68_17150	COG3162	membrane
AYR68_17155	COG0784	Response regulator, receiver
AYR68_17155	COG2205	protein histidine kinase activity
AYR68_17155	COG2198	Histidine kinase
AYR68_17180	COG3328	transposase activity
AYR68_17185	COG1522	sequence-specific DNA binding
AYR68_17190	COG1335	isochorismatase
AYR68_17195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR68_17205	COG0668	transmembrane transport
AYR68_17210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYR68_17215	COG1519	Transferase
AYR68_17220	COG1902	pentaerythritol trinitrate reductase activity
AYR68_17240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AYR68_17265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYR68_17265	COG0426	domain, Protein
AYR68_17270	COG4774	siderophore transport
AYR68_17275	COG2119	membrane
AYR68_17285	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYR68_17295	COG4942	peptidase
AYR68_17310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AYR68_17320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AYR68_17340	COG0189	ligase activity
AYR68_17360	COG0708	Exodeoxyribonuclease III
AYR68_17365	COG1393	Belongs to the ArsC family
AYR68_17380	COG3706	GGDEF domain
AYR68_17415	COG2351	hydroxyisourate hydrolase activity
AYR68_17420	COG2233	PERMEase
AYR68_17430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYR68_17440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AYR68_17445	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_17455	COG3150	esterase
AYR68_17475	COG0791	NLP P60 protein
AYR68_17475	COG1388	LysM domain
AYR68_17480	COG3501	Rhs element vgr protein
AYR68_17490	COG2918	glutathione biosynthetic process
AYR68_17505	COG2733	membrane
AYR68_17510	COG0436	Aminotransferase
AYR68_17515	COG0534	Mate efflux family protein
AYR68_17615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYR68_17620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYR68_17630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AYR68_17635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYR68_17690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR68_17740	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYR68_17770	COG0659	secondary active sulfate transmembrane transporter activity
AYR68_17775	COG0589	response to stress
AYR68_17810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYR68_17820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYR68_17835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYR68_17850	COG0318	PFAM AMP-dependent synthetase and ligase
AYR68_17860	COG0477	Major facilitator Superfamily
AYR68_17865	COG2860	membrane
AYR68_17875	COG1253	flavin adenine dinucleotide binding
AYR68_17895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AYR68_17930	COG0655	NAD(P)H dehydrogenase (quinone) activity
AYR68_17940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AYR68_17975	COG1309	transcriptional regulator
AYR68_18010	COG0758	DNA mediated transformation
AYR68_18020	COG0697	spore germination
AYR68_18025	COG1309	transcriptional regulator
AYR68_18040	COG0386	Belongs to the glutathione peroxidase family
AYR68_18105	COG1121	(ABC) transporter
AYR68_18110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYR68_18115	COG1280	lysine exporter protein (LysE YggA)
AYR68_18120	COG2837	iron assimilation
AYR68_18130	COG0281	malic enzyme
AYR68_18175	COG0519	Catalyzes the synthesis of GMP from XMP
AYR68_18175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYR68_18180	COG4399	Belongs to the UPF0754 family
AYR68_18185	COG2259	Doxx family
AYR68_18190	COG0586	Pfam SNARE associated Golgi protein
AYR68_18205	COG1192	Involved in chromosome partitioning
AYR68_18215	COG0271	Belongs to the BolA IbaG family
AYR68_18235	COG2267	carboxylic ester hydrolase activity
AYR68_18250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AYR68_18260	COG3321	synthase
AYR68_18260	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AYR68_18260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYR68_18260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYR68_18265	COG1960	acyl-CoA dehydrogenase activity
AYR68_18275	COG2197	response regulator
AYR68_18285	COG3916	Acyl-homoserine-lactone synthase
AYR68_18290	COG0477	Major facilitator Superfamily
AYR68_18295	COG1024	Enoyl-CoA hydratase
AYR68_18300	COG1024	Enoyl-CoA hydratase
AYR68_18305	COG1960	acyl-CoA dehydrogenase activity
AYR68_18310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYR68_18330	COG1113	amino acid transport
AYR68_18335	COG1113	amino acid transport
AYR68_18340	COG0251	oxidation-reduction process
AYR68_18355	COG1522	sequence-specific DNA binding
AYR68_18380	COG0564	pseudouridine synthase activity
AYR68_18430	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AYR68_18445	COG1802	Transcriptional regulator
AYR68_18450	COG1448	Aminotransferase
AYR68_18455	COG0277	FAD linked oxidase domain protein
AYR68_18465	COG2186	Transcriptional regulator
AYR68_18475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYR68_18480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AYR68_18495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYR68_18505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYR68_18515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYR68_18520	COG0438	transferase activity, transferring glycosyl groups
AYR68_18540	COG1216	Glycosyl transferase, family 2
AYR68_18545	COG5039	Polysaccharide pyruvyl transferase
AYR68_18555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AYR68_18560	COG1596	polysaccharide export
AYR68_18585	COG0728	peptidoglycan biosynthetic process
AYR68_18590	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYR68_18645	COG0546	phosphoglycolate phosphatase activity
AYR68_18650	COG1028	Short-chain dehydrogenase reductase Sdr
AYR68_18670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR68_18675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYR68_18680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AYR68_18685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYR68_18690	COG1116	anion transmembrane transporter activity
AYR68_18695	COG1309	transcriptional regulator
AYR68_18700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYR68_18710	COG0196	riboflavin kinase activity
AYR68_18715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYR68_18725	COG1047	Peptidyl-prolyl cis-trans
AYR68_18765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYR68_18790	COG0583	DNA-binding transcription factor activity
AYR68_18820	COG2951	lytic endotransglycosylase activity
AYR68_18825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AYR68_18840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYR68_18850	COG0671	phosphoesterase, PA-phosphatase related
AYR68_18855	COG0861	Integral membrane protein TerC family
AYR68_18865	COG0754	glutathionylspermidine amidase activity
AYR68_18875	COG0402	S-adenosylhomocysteine deaminase activity
AYR68_18895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYR68_18900	COG1230	cation diffusion facilitator family transporter
AYR68_18915	COG0706	membrane insertase activity
AYR68_18930	COG0230	Belongs to the bacterial ribosomal protein bL34 family