locus-tag	class	description
CK824_00010	COG0592	DNA-directed DNA polymerase activity
CK824_00020	COG0187	DNA topoisomerase II activity
CK824_00030	COG0586	Pfam SNARE associated Golgi protein
CK824_00035	COG0488	(ABC) transporter
CK824_00060	COG0596	Alpha beta hydrolase
CK824_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CK824_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK824_00115	COG0733	neurotransmitter:sodium symporter activity
CK824_00155	COG2233	PERMEase
CK824_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_00205	COG2814	Major facilitator Superfamily
CK824_00210	COG0656	L-ascorbic acid biosynthetic process
CK824_00215	COG0583	DNA-binding transcription factor activity
CK824_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_00235	COG1064	alcohol dehydrogenase
CK824_00240	COG2818	Glycosylase
CK824_00255	COG1194	a g-specific adenine glycosylase
CK824_00275	COG2983	Belongs to the UPF0260 family
CK824_00280	COG2133	pyrroloquinoline quinone binding
CK824_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK824_00290	COG2116	formate transmembrane transporter activity
CK824_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_00315	COG1335	isochorismatase
CK824_00320	COG0385	Bile acid
CK824_00325	COG0534	Mate efflux family protein
CK824_00330	COG1683	Conserved Protein
CK824_00350	COG0625	glutathione transferase activity
CK824_00360	COG1113	amino acid transport
CK824_00370	COG0523	cobalamin synthesis protein
CK824_00380	COG2188	Transcriptional regulator
CK824_00410	COG0010	Belongs to the arginase family
CK824_00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK824_00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CK824_00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK824_00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK824_00555	COG0534	Mate efflux family protein
CK824_00560	COG0436	Aminotransferase
CK824_00565	COG2733	membrane
CK824_00580	COG2918	glutathione biosynthetic process
CK824_00590	COG3501	Rhs element vgr protein
CK824_00595	COG0791	NLP P60 protein
CK824_00595	COG1388	LysM domain
CK824_00615	COG3150	esterase
CK824_00625	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CK824_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_00650	COG2233	PERMEase
CK824_00655	COG2351	hydroxyisourate hydrolase activity
CK824_00690	COG3706	GGDEF domain
CK824_00705	COG1393	Belongs to the ArsC family
CK824_00710	COG0708	Exodeoxyribonuclease III
CK824_00730	COG0189	ligase activity
CK824_00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK824_00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK824_00775	COG4942	peptidase
CK824_00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK824_00795	COG2119	membrane
CK824_00800	COG4774	siderophore transport
CK824_00805	COG0426	domain, Protein
CK824_00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK824_00850	COG1902	pentaerythritol trinitrate reductase activity
CK824_00855	COG1519	Transferase
CK824_00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK824_00865	COG0668	transmembrane transport
CK824_00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_00880	COG1335	isochorismatase
CK824_00885	COG1522	sequence-specific DNA binding
CK824_00890	COG3328	transposase activity
CK824_00915	COG0784	Response regulator, receiver
CK824_00915	COG2198	Histidine kinase
CK824_00915	COG2205	protein histidine kinase activity
CK824_00920	COG3162	membrane
CK824_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK824_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_00945	COG3706	GGDEF domain
CK824_00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK824_00960	COG1309	transcriptional regulator
CK824_00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK824_00980	COG0352	thiamine-phosphate diphosphorylase activity
CK824_00980	COG0351	phosphomethylpyrimidine kinase
CK824_00990	COG2814	Major facilitator Superfamily
CK824_01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CK824_01015	COG1113	amino acid transport
CK824_01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK824_01030	COG1012	belongs to the aldehyde dehydrogenase family
CK824_01040	COG1335	isochorismatase
CK824_01070	COG2814	Major facilitator Superfamily
CK824_01075	COG0583	DNA-binding transcription factor activity
CK824_01100	COG0667	Aldo Keto reductase
CK824_01135	COG1733	regulation of RNA biosynthetic process
CK824_01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK824_01225	COG2329	Antibiotic biosynthesis monooxygenase
CK824_01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CK824_01285	COG0427	acetyl-CoA hydrolase
CK824_01300	COG0745	RESPONSE REGULATOR receiver
CK824_01310	COG0659	secondary active sulfate transmembrane transporter activity
CK824_01315	COG4221	oxidoreductase activity
CK824_01325	COG0488	(ABC) transporter
CK824_01410	COG0833	amino acid
CK824_01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK824_01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK824_01475	COG2226	methyltransferase
CK824_01525	COG0067	glutamate synthase
CK824_01525	COG0069	glutamate synthase activity
CK824_01525	COG0070	glutamate synthase
CK824_01530	COG0493	'glutamate synthase
CK824_01540	COG1704	LemA family
CK824_01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CK824_01560	COG3307	-O-antigen
CK824_01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK824_01590	COG0194	GDP metabolic process
CK824_01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CK824_01660	COG5380	lipid catabolic process
CK824_01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CK824_01680	COG1061	Type III restriction enzyme res subunit
CK824_01690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_01695	COG1192	Involved in chromosome partitioning
CK824_01705	COG1061	Type III restriction enzyme res subunit
CK824_01725	COG1061	Type III restriction enzyme res subunit
CK824_01735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_01740	COG1192	Involved in chromosome partitioning
CK824_01750	COG1061	Type III restriction enzyme res subunit
CK824_01785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK824_01790	COG0277	FAD linked oxidase domain protein
CK824_01800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CK824_01805	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_01820	COG1289	transmembrane transporter activity
CK824_01830	COG0628	permease
CK824_01835	COG1192	Involved in chromosome partitioning
CK824_01865	COG0833	amino acid
CK824_01870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK824_01875	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK824_01885	COG1012	belongs to the aldehyde dehydrogenase family
CK824_01930	COG0583	DNA-binding transcription factor activity
CK824_01975	COG0517	IMP dehydrogenase activity
CK824_01980	COG1983	PspC domain protein
CK824_01990	COG1960	acyl-CoA dehydrogenase activity
CK824_02005	COG0408	coproporphyrinogen oxidase activity
CK824_02025	COG0513	Belongs to the DEAD box helicase family
CK824_02030	COG1127	ABC transporter
CK824_02035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CK824_02045	COG2854	intermembrane phospholipid transfer
CK824_02055	COG0598	Magnesium transport protein CorA
CK824_02065	COG0494	nUDIX hydrolase
CK824_02070	COG1040	competence protein
CK824_02075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK824_02095	COG1946	Acyl-CoA thioesterase
CK824_02100	COG1301	dicarboxylic acid transport
CK824_02115	COG1959	2 iron, 2 sulfur cluster binding
CK824_02120	COG1017	nitric oxide dioxygenase activity
CK824_02120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_02125	COG0433	COG0433 Predicted ATPase
CK824_02130	COG0626	cystathionine gamma-synthase activity
CK824_02250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CK824_02260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CK824_02285	COG1960	acyl-CoA dehydrogenase activity
CK824_02290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CK824_02320	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CK824_02325	COG0339	signal peptide processing
CK824_02330	COG0557	exoribonuclease II activity
CK824_02375	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK824_02380	COG2169	Transcriptional regulator
CK824_02385	COG0697	spore germination
CK824_02390	COG1295	ribonuclease BN
CK824_02425	COG1702	phosphate starvation-inducible protein PhoH
CK824_02435	COG0739	heme binding
CK824_02435	COG0741	lytic transglycosylase activity
CK824_02435	COG1196	nuclear chromosome segregation
CK824_02465	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CK824_02470	COG1183	phosphatidylcholine synthase activity
CK824_02515	COG1960	acyl-CoA dehydrogenase activity
CK824_02520	COG1309	transcriptional regulator
CK824_02535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK824_02540	COG1960	acyl-CoA dehydrogenase activity
CK824_02560	COG2969	positive regulation of protein catabolic process
CK824_02570	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK824_02585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CK824_02590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CK824_02610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK824_02620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK824_02625	COG1408	metallophosphoesterase
CK824_02635	COG2199	diguanylate cyclase activity
CK824_02680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_02680	COG3453	Protein conserved in bacteria
CK824_02695	COG1607	acyl-coa hydrolase
CK824_02725	COG2350	Protein conserved in bacteria
CK824_02735	COG0613	PHP domain protein
CK824_02740	COG3781	membrane
CK824_02750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK824_02755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK824_02765	COG1862	Preprotein translocase
CK824_02815	COG2205	protein histidine kinase activity
CK824_02820	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CK824_02840	COG0726	polysaccharide deacetylase
CK824_02845	COG0463	Glycosyl transferase, family 2
CK824_02850	COG0438	transferase activity, transferring glycosyl groups
CK824_02915	COG0625	glutathione transferase activity
CK824_02920	COG0583	DNA-binding transcription factor activity
CK824_02925	COG1960	acyl-CoA dehydrogenase activity
CK824_02930	COG1960	acyl-CoA dehydrogenase activity
CK824_02940	COG2205	protein histidine kinase activity
CK824_02945	COG0745	RESPONSE REGULATOR receiver
CK824_02950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CK824_02970	COG2096	Adenosyltransferase
CK824_02985	COG0133	tryptophan synthase activity
CK824_03020	COG0285	dihydrofolate synthase activity
CK824_03040	COG0450	alkyl hydroperoxide reductase
CK824_03055	COG0477	Major facilitator Superfamily
CK824_03060	COG1272	protein, Hemolysin III
CK824_03090	COG0183	Belongs to the thiolase family
CK824_03095	COG2207	Transcriptional regulator
CK824_03115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_03135	COG0183	Belongs to the thiolase family
CK824_03145	COG2885	chlorophyll binding
CK824_03145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CK824_03155	COG1690	Belongs to the RtcB family
CK824_03160	COG0833	amino acid
CK824_03170	COG2233	PERMEase
CK824_03200	COG2094	Belongs to the DNA glycosylase MPG family
CK824_03205	COG4772	TonB-dependent receptor
CK824_03210	COG1902	pentaerythritol trinitrate reductase activity
CK824_03225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_03230	COG0354	folic acid binding
CK824_03240	COG3189	MarR family transcriptional regulator
CK824_03245	COG2824	Alkylphosphonate utilization operon protein PhnA
CK824_03250	COG3422	double-strand break repair
CK824_03290	COG0840	transmembrane signaling receptor activity
CK824_03310	COG5510	response to toxic substance
CK824_03320	COG2832	Protein of unknown function (DUF454)
CK824_03325	COG1376	ErfK ybiS ycfS ynhG family protein
CK824_03375	COG1289	transmembrane transporter activity
CK824_03380	COG2814	Major facilitator Superfamily
CK824_03400	COG1115	amino acid carrier protein
CK824_03405	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK824_03410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK824_03415	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CK824_03445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CK824_03455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CK824_03460	COG1077	Cell shape determining protein MreB Mrl
CK824_03465	COG1792	Involved in formation and maintenance of cell shape
CK824_03470	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK824_03475	COG0424	maF-like protein
CK824_03480	COG1530	ribonuclease E activity
CK824_03490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_03510	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_03535	COG2207	Transcriptional regulator
CK824_03555	COG1113	amino acid transport
CK824_03560	COG2828	Protein conserved in bacteria
CK824_03565	COG0142	geranyltranstransferase activity
CK824_03570	COG2315	Protein conserved in bacteria
CK824_03585	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK824_03610	COG2194	sulfuric ester hydrolase activity
CK824_03615	COG0745	RESPONSE REGULATOR receiver
CK824_03620	COG0642	Histidine kinase
CK824_03630	COG0004	ammonium transporteR
CK824_03640	COG0583	DNA-binding transcription factor activity
CK824_03660	COG0525	valine-tRNA ligase activity
CK824_03670	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_03680	COG0393	Putative heavy-metal-binding
CK824_03685	COG0393	Putative heavy-metal-binding
CK824_03690	COG1538	Outer membrane efflux protein
CK824_03700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_03705	COG0671	phosphoesterase, PA-phosphatase related
CK824_03735	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK824_03750	COG1648	precorrin-2 dehydrogenase activity
CK824_03750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK824_03755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK824_03760	COG1733	regulation of RNA biosynthetic process
CK824_03770	COG0531	amino acid
CK824_03785	COG0321	lipoyl(octanoyl) transferase activity
CK824_03790	COG2921	Belongs to the UPF0250 family
CK824_03830	COG2009	succinate dehydrogenase
CK824_03835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CK824_03840	COG1053	succinate dehydrogenase
CK824_03845	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK824_03870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_03890	COG2354	Protein conserved in bacteria
CK824_03895	COG2321	neutral zinc metallopeptidase
CK824_03930	COG2843	Capsule synthesis protein
CK824_03945	COG0589	response to stress
CK824_03965	COG0505	Belongs to the CarA family
CK824_03995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK824_04000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK824_04050	COG0477	Major facilitator Superfamily
CK824_04055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CK824_04075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CK824_04100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_04105	COG0584	glycerophosphoryl diester phosphodiesterase
CK824_04125	COG0741	lytic transglycosylase activity
CK824_04150	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK824_04165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_04190	COG0778	Nitroreductase
CK824_04205	COG1929	Belongs to the glycerate kinase type-1 family
CK824_04210	COG0243	molybdopterin cofactor binding
CK824_04215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK824_04220	COG3339	Conserved Protein
CK824_04230	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CK824_04245	COG1113	amino acid transport
CK824_04255	COG0019	diaminopimelate decarboxylase activity
CK824_04265	COG1280	lysine exporter protein (LysE YggA)
CK824_04270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK824_04300	COG0463	Glycosyl transferase, family 2
CK824_04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_04350	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK824_04355	COG1136	(ABC) transporter
CK824_04360	COG0658	competence protein
CK824_04360	COG2333	competence protein COMEC
CK824_04370	COG0616	signal peptide processing
CK824_04370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK824_04375	COG0596	Alpha beta hydrolase
CK824_04380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK824_04390	COG0628	permease
CK824_04425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK824_04445	COG0823	Involved in the tonB-independent uptake of proteins
CK824_04465	COG0824	Thioesterase
CK824_04470	COG1473	amidohydrolase
CK824_04490	COG0047	phosphoribosylformylglycinamidine synthase activity
CK824_04490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CK824_04495	COG2814	Major facilitator Superfamily
CK824_04500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK824_04505	COG1024	Enoyl-CoA hydratase
CK824_04510	COG1051	belongs to the nudix hydrolase family
CK824_04510	COG1056	cytidyltransferase-related domain
CK824_04520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK824_04535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CK824_04550	COG4625	pathogenesis
CK824_04555	COG0583	DNA-binding transcription factor activity
CK824_04560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CK824_04565	COG4208	sulfate ABC transporter
CK824_04570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CK824_04580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CK824_04585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK824_04590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK824_04610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK824_04625	COG0681	Belongs to the peptidase S26 family
CK824_04640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CK824_04650	COG1381	Involved in DNA repair and RecF pathway recombination
CK824_04655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CK824_04665	COG4221	oxidoreductase activity
CK824_04715	COG0556	nucleotide-excision repair
CK824_04770	COG2070	2-Nitropropane dioxygenase
CK824_04800	COG1215	transferase activity, transferring glycosyl groups
CK824_04815	COG0415	Belongs to the DNA photolyase family
CK824_04825	COG1252	NADH dehydrogenase
CK824_04830	COG1686	Belongs to the peptidase S11 family
CK824_04845	COG1187	pseudouridine synthase activity
CK824_04870	COG0477	Major facilitator Superfamily
CK824_04875	COG0583	DNA-binding transcription factor activity
CK824_04890	COG0612	Peptidase, M16
CK824_04915	COG0352	thiamine-phosphate diphosphorylase activity
CK824_04950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_04965	COG1309	transcriptional regulator
CK824_04975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK824_04980	COG0076	glutamate decarboxylase activity
CK824_04990	COG1522	sequence-specific DNA binding
CK824_04995	COG3961	Belongs to the TPP enzyme family
CK824_05000	COG1113	amino acid transport
CK824_05005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_05010	COG0573	inorganic phosphate transmembrane transporter activity
CK824_05020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK824_05025	COG0616	signal peptide processing
CK824_05060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK824_05065	COG1686	Belongs to the peptidase S11 family
CK824_05090	COG0583	DNA-binding transcription factor activity
CK824_05095	COG1067	ATP-dependent peptidase activity
CK824_05140	COG1966	Carbon starvation protein
CK824_05145	COG2879	small protein
CK824_05180	COG2508	Transcriptional regulator
CK824_05180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CK824_05200	COG1113	amino acid transport
CK824_05205	COG0583	DNA-binding transcription factor activity
CK824_05210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_05215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_05230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_05235	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CK824_05235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_05270	COG2814	Major facilitator Superfamily
CK824_05275	COG4948	Mandelate Racemase Muconate Lactonizing
CK824_05285	COG1309	transcriptional regulator
CK824_05305	COG1741	Belongs to the pirin family
CK824_05315	COG2964	Protein conserved in bacteria
CK824_05330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_05335	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK824_05340	COG4605	iron ion homeostasis
CK824_05345	COG4604	ABC transporter, ATP-binding protein
CK824_05350	COG4607	ABC-type enterochelin transport system periplasmic component
CK824_05355	COG4774	siderophore transport
CK824_05365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_05370	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK824_05375	COG1535	isochorismatase
CK824_05375	COG3433	isochorismatase activity
CK824_05390	COG1132	(ABC) transporter
CK824_05400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CK824_05410	COG1169	isochorismate synthase
CK824_05425	COG3739	integral membrane protein
CK824_05455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CK824_05485	COG0308	aminopeptidase N
CK824_05490	COG0512	Glutamine amidotransferase of anthranilate synthase
CK824_05500	COG3104	oligopeptide transport
CK824_05515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CK824_05550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK824_05555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK824_05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK824_05580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK824_05585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK824_05590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CK824_05605	COG1960	acyl-CoA dehydrogenase activity
CK824_05610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK824_05615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_05625	COG2223	nitrite transmembrane transporter activity
CK824_05635	COG0024	Methionine aminopeptidase
CK824_05640	COG0052	Belongs to the universal ribosomal protein uS2 family
CK824_05655	COG2207	Transcriptional regulator
CK824_05680	COG2951	lytic endotransglycosylase activity
CK824_05685	COG0772	Belongs to the SEDS family
CK824_05700	COG0842	Transport permease protein
CK824_05705	COG1131	(ABC) transporter
CK824_05740	COG1538	Outer membrane efflux protein
CK824_05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_05775	COG4215	(ABC) transporter
CK824_05780	COG4160	amino acid transport
CK824_05785	COG4598	ABC transporter
CK824_05795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK824_05805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_05820	COG1720	tRNA m6t6A37 methyltransferase activity
CK824_05840	COG0745	RESPONSE REGULATOR receiver
CK824_05845	COG0642	Histidine kinase
CK824_05855	COG0494	nUDIX hydrolase
CK824_05865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK824_05870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK824_05875	COG3139	Protein of unknown function (DUF1315)
CK824_05880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK824_05890	COG1301	dicarboxylic acid transport
CK824_05895	COG1960	acyl-CoA dehydrogenase activity
CK824_05900	COG2819	hydrolase of the alpha beta superfamily
CK824_05910	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CK824_05920	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK824_05925	COG1234	tRNA 3'-trailer cleavage
CK824_05955	COG2363	Small membrane protein
CK824_05975	COG0513	Belongs to the DEAD box helicase family
CK824_05985	COG0778	Nitroreductase
CK824_06015	COG1286	toxin biosynthetic process
CK824_06040	COG4783	chaperone-mediated protein folding
CK824_06045	COG1610	YqeY-like protein
CK824_06050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CK824_06145	COG3111	PFAM Bacterial OB fold (BOF) protein
CK824_06170	COG3243	poly(R)-hydroxyalkanoic acid synthase
CK824_06175	COG0786	glutamate:sodium symporter activity
CK824_06185	COG2186	Transcriptional regulator
CK824_06240	COG0477	Major facilitator Superfamily
CK824_06270	COG2985	domain, Protein
CK824_06280	COG2995	paraquat-inducible protein a
CK824_06285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK824_06285	COG3008	intermembrane lipid transfer
CK824_06295	COG1794	racemase activity, acting on amino acids and derivatives
CK824_06325	COG1301	dicarboxylic acid transport
CK824_06335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_06340	COG2011	ABC-type metal ion transport system permease component
CK824_06345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK824_06350	COG1464	Belongs to the NlpA lipoprotein family
CK824_06355	COG0151	Belongs to the GarS family
CK824_06360	COG0138	bifunctional purine biosynthesis protein purh
CK824_06365	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CK824_06395	COG2308	Evidence 4 Homologs of previously reported genes of
CK824_06405	COG1305	Transglutaminase-like
CK824_06415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK824_06420	COG0305	Participates in initiation and elongation during chromosome replication
CK824_06445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CK824_06455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK824_06460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK824_06485	COG1649	PFAM Uncharacterised BCR, COG1649
CK824_06485	COG0726	polysaccharide deacetylase
CK824_06490	COG1215	transferase activity, transferring glycosyl groups
CK824_06495	COG3658	cytochrome
CK824_06505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_06525	COG0583	DNA-binding transcription factor activity
CK824_06545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_06550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_06565	COG1960	acyl-CoA dehydrogenase activity
CK824_06570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_06575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_06600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CK824_06605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CK824_06615	COG2205	protein histidine kinase activity
CK824_06620	COG0745	RESPONSE REGULATOR receiver
CK824_06625	COG0174	glutamine synthetase
CK824_06645	COG0729	surface antigen
CK824_06675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK824_06680	COG2814	Major facilitator Superfamily
CK824_06695	COG0583	DNA-binding transcription factor activity
CK824_06710	COG1187	pseudouridine synthase activity
CK824_06730	COG0802	atpase or kinase
CK824_06735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CK824_06745	COG1923	regulation of RNA biosynthetic process
CK824_06750	COG0697	spore germination
CK824_06765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_06780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK824_06780	COG0519	Catalyzes the synthesis of GMP from XMP
CK824_06785	COG4302	ethanolamine ammonia-lyase activity
CK824_06790	COG4303	Ethanolamine ammonia lyase large subunit
CK824_06795	COG0531	amino acid
CK824_06815	COG1454	alcohol dehydrogenase
CK824_06820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK824_06830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CK824_06850	COG0308	aminopeptidase N
CK824_06860	COG4221	oxidoreductase activity
CK824_06870	COG1605	Chorismate mutase
CK824_06890	COG1309	transcriptional regulator
CK824_06900	COG0668	transmembrane transport
CK824_06935	COG4773	Receptor
CK824_06955	COG0488	(ABC) transporter
CK824_06960	COG0589	response to stress
CK824_06980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CK824_06990	COG3135	benzoate transporter
CK824_06995	COG1522	sequence-specific DNA binding
CK824_07010	COG0583	DNA-binding transcription factor activity
CK824_07020	COG0183	Belongs to the thiolase family
CK824_07060	COG0824	Thioesterase
CK824_07065	COG1454	alcohol dehydrogenase
CK824_07075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK824_07095	COG0069	glutamate synthase activity
CK824_07270	COG5410	chromosome segregation
CK824_07375	COG1598	PFAM Uncharacterised protein family UPF0150
CK824_07460	COG2814	Major facilitator Superfamily
CK824_07475	COG0511	ligase activity, forming carbon-carbon bonds
CK824_07490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_07490	COG1116	anion transmembrane transporter activity
CK824_07495	COG0745	RESPONSE REGULATOR receiver
CK824_07505	COG2146	nitrite reductase [NAD(P)H] activity
CK824_07505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_07510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_07515	COG0243	molybdopterin cofactor binding
CK824_07525	COG0243	molybdopterin cofactor binding
CK824_07530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK824_07545	COG0315	cyclic pyranopterin monophosphate synthase activity
CK824_07545	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK824_07550	COG0303	'Molybdopterin
CK824_07560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_07565	COG0697	spore germination
CK824_07585	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CK824_07590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK824_07650	COG2204	response regulator
CK824_07655	COG3852	Histidine kinase
CK824_07675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CK824_07680	COG0575	Belongs to the CDS family
CK824_07715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_07730	COG2137	regulation of response to DNA damage stimulus
CK824_07740	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK824_07745	COG1011	Hydrolase
CK824_07770	COG1522	sequence-specific DNA binding
CK824_07780	COG1113	amino acid transport
CK824_07800	COG0659	secondary active sulfate transmembrane transporter activity
CK824_07815	COG3316	Transposase and inactivated derivatives
CK824_07825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CK824_07840	COG0640	Transcriptional regulator
CK824_07845	COG0798	PFAM Bile acid sodium symporter
CK824_07850	COG0583	DNA-binding transcription factor activity
CK824_07865	COG3634	alkyl hydroperoxide reductase activity
CK824_07905	COG0436	Aminotransferase
CK824_07915	COG0386	Belongs to the glutathione peroxidase family
CK824_07955	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CK824_07980	COG0012	GTP binding
CK824_07985	COG2011	ABC-type metal ion transport system permease component
CK824_07990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK824_08000	COG1464	Belongs to the NlpA lipoprotein family
CK824_08030	COG0765	amino acid transport
CK824_08035	COG0765	amino acid transport
CK824_08040	COG1126	abc transporter atp-binding protein
CK824_08050	COG1522	sequence-specific DNA binding
CK824_08065	COG1309	transcriptional regulator
CK824_08095	COG0583	DNA-binding transcription factor activity
CK824_08105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK824_08115	COG0697	spore germination
CK824_08145	COG3121	Chaperone
CK824_08150	COG3539	Fimbrial protein
CK824_08175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CK824_08175	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CK824_08220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK824_08230	COG2353	YceI-like domain
CK824_08240	COG3698	Phosphodiester glycosidase
CK824_08255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK824_08260	COG0506	proline dehydrogenase activity
CK824_08260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CK824_08260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CK824_08270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK824_08275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK824_08280	COG3316	Transposase and inactivated derivatives
CK824_08315	COG0482	sulfurtransferase activity
CK824_08335	COG3173	Aminoglycoside phosphotransferase
CK824_08345	COG2433	Pfam Transposase IS66
CK824_08370	COG3316	Transposase and inactivated derivatives
CK824_08390	COG3300	MHYT domain
CK824_08390	COG5001	Diguanylate cyclase
CK824_08410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CK824_08410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK824_08410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK824_08415	COG1105	Belongs to the carbohydrate kinase PfkB family
CK824_08420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK824_08420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK824_08450	COG0024	Methionine aminopeptidase
CK824_08455	COG0583	DNA-binding transcription factor activity
CK824_08465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CK824_08470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK824_08475	COG0517	IMP dehydrogenase activity
CK824_08475	COG0516	GMP reductase activity
CK824_08500	COG0552	protein localization to endoplasmic reticulum
CK824_08510	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CK824_08525	COG4890	Cyd operon protein YbgT
CK824_08530	COG1294	oxidase, subunit
CK824_08545	COG1585	Membrane protein implicated in regulation of membrane protease activity
CK824_08555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK824_08560	COG4774	siderophore transport
CK824_08575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK824_08580	COG0569	domain protein
CK824_08585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK824_08615	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CK824_08620	COG0542	response to heat
CK824_08630	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK824_08645	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_08645	COG1902	pentaerythritol trinitrate reductase activity
CK824_08690	COG2323	membrane
CK824_08695	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK824_08705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_08710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_08715	COG0183	Belongs to the thiolase family
CK824_08720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK824_08725	COG0596	Alpha beta hydrolase
CK824_08730	COG2271	Major facilitator Superfamily
CK824_08735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK824_08740	COG3485	protocatechuate 3,4-dioxygenase
CK824_08745	COG3485	protocatechuate 3,4-dioxygenase
CK824_08750	COG0710	3-dehydroquinate dehydratase activity
CK824_08755	COG3420	alginic acid biosynthetic process
CK824_08760	COG3659	wide pore channel activity
CK824_08765	COG4993	Dehydrogenase
CK824_08775	COG2391	methyltransferase activity
CK824_08790	COG1414	Transcriptional regulator
CK824_08795	COG0583	DNA-binding transcription factor activity
CK824_08800	COG1960	acyl-CoA dehydrogenase activity
CK824_08825	COG2814	Major facilitator Superfamily
CK824_08835	COG0154	amidase activity
CK824_08855	COG4638	Rieske (2fe-2S)
CK824_08865	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_08875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_08885	COG3733	amine oxidase
CK824_08895	COG1012	belongs to the aldehyde dehydrogenase family
CK824_08905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_08910	COG0183	Belongs to the thiolase family
CK824_08915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_08920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_08930	COG4829	muconolactone delta-isomerase
CK824_08935	COG4948	Mandelate Racemase Muconate Lactonizing
CK824_08940	COG0583	DNA-binding transcription factor activity
CK824_08950	COG2186	Transcriptional regulator
CK824_08970	COG1012	belongs to the aldehyde dehydrogenase family
CK824_08990	COG1960	acyl-CoA dehydrogenase activity
CK824_08995	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_09000	COG3829	transcription factor binding
CK824_09010	COG3162	membrane
CK824_09025	COG1012	belongs to the aldehyde dehydrogenase family
CK824_09040	COG0753	catalase activity
CK824_09065	COG1846	Transcriptional regulator
CK824_09070	COG1902	pentaerythritol trinitrate reductase activity
CK824_09070	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_09080	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK824_09110	COG1309	transcriptional regulator
CK824_09120	COG1335	isochorismatase
CK824_09125	COG0583	DNA-binding transcription factor activity
CK824_09135	COG0475	glutathione-regulated potassium exporter activity
CK824_09135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_09145	COG1473	amidohydrolase
CK824_09160	COG2831	hemolysin activation secretion protein
CK824_09165	COG3210	domain, Protein
CK824_09210	COG0583	DNA-binding transcription factor activity
CK824_09235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK824_09240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK824_09260	COG1566	PFAM secretion protein HlyD family protein
CK824_09275	COG1012	belongs to the aldehyde dehydrogenase family
CK824_09280	COG0129	dihydroxy-acid dehydratase activity
CK824_09290	COG0583	DNA-binding transcription factor activity
CK824_09295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK824_09305	COG2084	Dehydrogenase
CK824_09310	COG2207	Transcriptional regulator
CK824_09325	COG1064	alcohol dehydrogenase
CK824_09340	COG1120	ATPase activity
CK824_09360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK824_09480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CK824_09530	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_09545	COG2207	Transcriptional regulator
CK824_09555	COG2205	protein histidine kinase activity
CK824_09560	COG0745	RESPONSE REGULATOR receiver
CK824_09565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_09570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK824_09575	COG1538	Outer membrane efflux protein
CK824_09585	COG2072	flavoprotein involved in K transport
CK824_09605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_09625	COG3539	Fimbrial protein
CK824_09655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CK824_09665	COG0753	catalase activity
CK824_09680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK824_09745	COG1535	isochorismatase
CK824_09745	COG3433	isochorismatase activity
CK824_09750	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_09755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CK824_09760	COG4149	molybdate abc transporter
CK824_09765	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK824_09775	COG4638	Rieske (2fe-2S)
CK824_09780	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CK824_09785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_09785	COG0543	2 iron, 2 sulfur cluster binding
CK824_09800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_09810	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_09815	COG0412	Dienelactone hydrolase
CK824_09825	COG2207	Transcriptional regulator
CK824_09835	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_09840	COG2610	gluconate transmembrane transporter activity
CK824_09850	COG0583	DNA-binding transcription factor activity
CK824_09860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_09865	COG2031	fatty acid transporter
CK824_09870	COG0183	Belongs to the thiolase family
CK824_09875	COG0583	DNA-binding transcription factor activity
CK824_09880	COG0583	DNA-binding transcription factor activity
CK824_09895	COG1027	Aspartate ammonia-lyase
CK824_09905	COG0477	Major facilitator Superfamily
CK824_09925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_09930	COG4521	taurine ABC transporter
CK824_09955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK824_09960	COG1733	regulation of RNA biosynthetic process
CK824_09965	COG3708	Transcriptional regulator
CK824_09965	COG2207	Transcriptional regulator
CK824_09980	COG0730	response to heat
CK824_09990	COG3453	Protein conserved in bacteria
CK824_09990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_10000	COG3781	membrane
CK824_10005	COG1063	alcohol dehydrogenase
CK824_10015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_10020	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK824_10025	COG0022	dehydrogenase e1 component
CK824_10030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK824_10035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK824_10050	COG3706	GGDEF domain
CK824_10065	COG0133	tryptophan synthase activity
CK824_10075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK824_10110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CK824_10135	COG2226	methyltransferase
CK824_10190	COG0842	Transport permease protein
CK824_10195	COG0842	Transport permease protein
CK824_10200	COG1131	(ABC) transporter
CK824_10215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_10220	COG4773	Receptor
CK824_10240	COG0730	response to heat
CK824_10245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK824_10265	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CK824_10320	COG4264	IucA IucC family
CK824_10325	COG4264	IucA IucC family
CK824_10345	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK824_10360	COG1960	acyl-CoA dehydrogenase activity
CK824_10365	COG1960	acyl-CoA dehydrogenase activity
CK824_10370	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK824_10375	COG2207	Transcriptional regulator
CK824_10380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK824_10385	COG0776	regulation of translation
CK824_10410	COG0822	iron-sulfur transferase activity
CK824_10415	COG0316	Belongs to the HesB IscA family
CK824_10445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK824_10465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK824_10470	COG0702	epimerase
CK824_10505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK824_10515	COG0339	signal peptide processing
CK824_10565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK824_10570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CK824_10600	COG0776	regulation of translation
CK824_10620	COG0590	tRNA wobble adenosine to inosine editing
CK824_10650	COG2165	general secretion pathway protein
CK824_10665	COG0084	hydrolase, TatD family'
CK824_10685	COG1663	tetraacyldisaccharide 4'-kinase activity
CK824_10690	COG1132	(ABC) transporter
CK824_10700	COG0811	peptide transport
CK824_10705	COG1475	DNA binding
CK824_10710	COG1192	Involved in chromosome partitioning
CK824_10720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK824_10735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK824_10740	COG0191	fructose-bisphosphate aldolase activity
CK824_10760	COG0424	maF-like protein
CK824_10765	COG2850	peptidyl-arginine hydroxylation
CK824_10775	COG0640	Transcriptional regulator
CK824_10785	COG3619	membrane
CK824_10790	COG3122	Protein conserved in bacteria
CK824_10795	COG1132	(ABC) transporter
CK824_10820	COG3316	Transposase and inactivated derivatives
CK824_10835	COG0477	Major facilitator Superfamily
CK824_10860	COG1271	oxidase subunit
CK824_10865	COG1294	oxidase, subunit
CK824_10875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_10895	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CK824_10915	COG3052	prosthetic group binding
CK824_10920	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CK824_10930	COG2814	Major facilitator Superfamily
CK824_10950	COG1346	cytolysis
CK824_10960	COG0583	DNA-binding transcription factor activity
CK824_10965	COG0625	glutathione transferase activity
CK824_10970	COG0625	glutathione transferase activity
CK824_10975	COG0583	DNA-binding transcription factor activity
CK824_10990	COG1045	serine acetyltransferase
CK824_10995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK824_11000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK824_11005	COG1280	lysine exporter protein (LysE YggA)
CK824_11020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK824_11025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK824_11030	COG1126	abc transporter atp-binding protein
CK824_11035	COG0765	amino acid transport
CK824_11040	COG0765	amino acid transport
CK824_11060	COG2205	protein histidine kinase activity
CK824_11060	COG0784	Response regulator, receiver
CK824_11080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CK824_11100	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_11145	COG0583	DNA-binding transcription factor activity
CK824_11165	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_11170	COG1309	transcriptional regulator
CK824_11175	COG1960	acyl-CoA dehydrogenase activity
CK824_11180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK824_11185	COG1024	Enoyl-CoA hydratase
CK824_11200	COG0583	DNA-binding transcription factor activity
CK824_11215	COG1960	acyl-CoA dehydrogenase activity
CK824_11225	COG2814	Major facilitator Superfamily
CK824_11235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_11240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_11245	COG2814	Major facilitator Superfamily
CK824_11250	COG1960	acyl-CoA dehydrogenase activity
CK824_11255	COG1024	Enoyl-CoA hydratase
CK824_11260	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_11270	COG0183	Belongs to the thiolase family
CK824_11280	COG2814	Major facilitator Superfamily
CK824_11290	COG1024	Enoyl-CoA hydratase
CK824_11305	COG1960	acyl-CoA dehydrogenase activity
CK824_11310	COG2814	Major facilitator Superfamily
CK824_11315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK824_11320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK824_11335	COG3842	ATPase activity
CK824_11340	COG1840	ABC-type Fe3 transport system, periplasmic component
CK824_11350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_11355	COG1414	Transcriptional regulator
CK824_11365	COG0583	DNA-binding transcription factor activity
CK824_11370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK824_11375	COG1012	belongs to the aldehyde dehydrogenase family
CK824_11385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK824_11395	COG1012	belongs to the aldehyde dehydrogenase family
CK824_11400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_11405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_11410	COG2267	carboxylic ester hydrolase activity
CK824_11430	COG3038	cytochrome b561
CK824_11435	COG0753	catalase activity
CK824_11475	COG2050	protein possibly involved in aromatic compounds catabolism
CK824_11485	COG3327	negative regulation of DNA-templated transcription, initiation
CK824_11490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CK824_11495	COG0183	Belongs to the thiolase family
CK824_11500	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK824_11505	COG1024	Enoyl-CoA hydratase
CK824_11510	COG1024	Enoyl-CoA hydratase
CK824_11515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_11520	COG2151	metal-sulfur cluster biosynthetic enzyme
CK824_11525	COG3396	Phenylacetate-CoA oxygenase
CK824_11530	COG3460	Phenylacetate-CoA oxygenase
CK824_11535	COG3396	Phenylacetate-CoA oxygenase
CK824_11540	COG1012	belongs to the aldehyde dehydrogenase family
CK824_11540	COG2030	dehydratase
CK824_11545	COG1760	l-serine dehydratase
CK824_11550	COG0531	amino acid
CK824_11555	COG1012	belongs to the aldehyde dehydrogenase family
CK824_11570	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_11580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_11600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_11615	COG0789	Transcriptional regulator
CK824_11630	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK824_11645	COG2807	transmembrane transport
CK824_11650	COG0590	tRNA wobble adenosine to inosine editing
CK824_11670	COG0864	Transcriptional regulator
CK824_11690	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_11695	COG0439	Biotin carboxylase
CK824_11710	COG1063	alcohol dehydrogenase
CK824_11720	COG1309	transcriptional regulator
CK824_11745	COG0038	chloride channel
CK824_11750	COG4770	biotin carboxylase activity
CK824_11770	COG1914	H( )-stimulated, divalent metal cation uptake system
CK824_11775	COG0583	DNA-binding transcription factor activity
CK824_11790	COG3209	COG3209 Rhs family protein
CK824_11795	COG3501	Rhs element vgr protein
CK824_11830	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK824_11850	COG2814	Major facilitator Superfamily
CK824_11865	COG1560	Kdo2-lipid A biosynthetic process
CK824_11875	COG5006	permease, DMT superfamily
CK824_11880	COG1522	sequence-specific DNA binding
CK824_11895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CK824_11935	COG1538	Outer membrane efflux protein
CK824_11940	COG1137	ATPase activity
CK824_11945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CK824_11955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CK824_11960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK824_11960	COG0517	IMP dehydrogenase activity
CK824_11995	COG1733	regulation of RNA biosynthetic process
CK824_12000	COG2814	Major facilitator Superfamily
CK824_12040	COG1278	Cold shock
CK824_12045	COG1280	lysine exporter protein (LysE YggA)
CK824_12080	COG1570	exodeoxyribonuclease VII activity
CK824_12135	COG0583	DNA-binding transcription factor activity
CK824_12140	COG4638	Rieske (2fe-2S)
CK824_12145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CK824_12150	COG0543	2 iron, 2 sulfur cluster binding
CK824_12150	COG0633	Ferredoxin
CK824_12155	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_12160	COG3135	benzoate transporter
CK824_12165	COG2814	Major facilitator Superfamily
CK824_12180	COG1643	Atp-dependent helicase
CK824_12185	COG0450	alkyl hydroperoxide reductase
CK824_12195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CK824_12205	COG3634	alkyl hydroperoxide reductase activity
CK824_12225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CK824_12230	COG0625	glutathione transferase activity
CK824_12240	COG2885	chlorophyll binding
CK824_12290	COG1765	OsmC-like protein
CK824_12305	COG0667	Aldo Keto reductase
CK824_12320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CK824_12330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK824_12350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CK824_12360	COG3038	cytochrome b561
CK824_12365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK824_12370	COG2252	PERMEase
CK824_12380	COG2072	flavoprotein involved in K transport
CK824_12395	COG3316	Transposase and inactivated derivatives
CK824_12420	COG0531	amino acid
CK824_12430	COG1113	amino acid transport
CK824_12475	COG3209	COG3209 Rhs family protein
CK824_12480	COG3501	Rhs element vgr protein
CK824_12500	COG4269	membrane
CK824_12515	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_12515	COG1902	pentaerythritol trinitrate reductase activity
CK824_12525	COG3706	GGDEF domain
CK824_12525	COG5001	Diguanylate cyclase
CK824_12525	COG2203	Gaf domain
CK824_12525	COG4251	negative regulation of phosphorylation
CK824_12535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_12555	COG4172	Belongs to the ABC transporter superfamily
CK824_12560	COG4239	(ABC) transporter, permease
CK824_12565	COG4174	ABC transporter (Permease)
CK824_12575	COG1388	LysM domain
CK824_12575	COG0741	lytic transglycosylase activity
CK824_12575	COG1388	LysM domain
CK824_12575	COG0741	lytic transglycosylase activity
CK824_12580	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_12620	COG0583	DNA-binding transcription factor activity
CK824_12625	COG1279	arginine transmembrane transporter activity
CK824_12645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_12650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_12655	COG0006	proline dipeptidase activity
CK824_12690	COG2194	sulfuric ester hydrolase activity
CK824_12865	COG5410	chromosome segregation
CK824_13035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK824_13060	COG3384	dioxygenase
CK824_13070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK824_13075	COG2878	Part of a membrane complex involved in electron transport
CK824_13080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK824_13105	COG0768	penicillin binding
CK824_13110	COG0742	ribosomal rna small subunit methyltransferase
CK824_13125	COG0830	nickel cation binding
CK824_13135	COG0804	urea catabolic process
CK824_13175	COG1253	flavin adenine dinucleotide binding
CK824_13185	COG2851	Citrate transporter
CK824_13235	COG1773	rubredoxin
CK824_13240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_13250	COG0583	DNA-binding transcription factor activity
CK824_13280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CK824_13285	COG4181	ATPase activity
CK824_13330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CK824_13350	COG0306	phosphate transporter
CK824_13360	COG3958	Transketolase
CK824_13365	COG3959	Transketolase, thiamine diphosphate binding domain
CK824_13370	COG2271	Major facilitator Superfamily
CK824_13375	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_13380	COG0583	DNA-binding transcription factor activity
CK824_13400	COG2223	nitrite transmembrane transporter activity
CK824_13405	COG2207	Transcriptional regulator
CK824_13410	COG2066	Belongs to the glutaminase family
CK824_13415	COG0242	peptide deformylase activity
CK824_13420	COG0477	Major facilitator Superfamily
CK824_13430	COG0028	Belongs to the TPP enzyme family
CK824_13445	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_13450	COG2267	carboxylic ester hydrolase activity
CK824_13460	COG2271	Major facilitator Superfamily
CK824_13465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_13475	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_13495	COG1414	Transcriptional regulator
CK824_13510	COG1024	Enoyl-CoA hydratase
CK824_13520	COG1215	transferase activity, transferring glycosyl groups
CK824_13525	COG0726	polysaccharide deacetylase
CK824_13525	COG1649	PFAM Uncharacterised BCR, COG1649
CK824_13535	COG4681	YaeQ
CK824_13545	COG0523	cobalamin synthesis protein
CK824_13555	COG1607	acyl-coa hydrolase
CK824_13565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_13570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_13575	COG1309	transcriptional regulator
CK824_13600	COG2040	homocysteine
CK824_13605	COG0531	amino acid
CK824_13630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_13635	COG0477	Major facilitator Superfamily
CK824_13705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK824_13790	COG0592	DNA-directed DNA polymerase activity
CK824_13830	COG2026	Addiction module toxin, RelE StbE family
CK824_13980	COG3755	Protein conserved in bacteria
CK824_14025	COG1484	DNA-dependent DNA replication
CK824_14135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_14165	COG0405	Gamma-glutamyltransferase
CK824_14170	COG2814	Major facilitator Superfamily
CK824_14180	COG2050	protein possibly involved in aromatic compounds catabolism
CK824_14195	COG1090	epimerase
CK824_14215	COG0420	3'-5' exonuclease activity
CK824_14240	COG0735	belongs to the Fur family
CK824_14245	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK824_14270	COG0121	glutamine amidotransferase
CK824_14285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK824_14295	COG0210	DNA helicase
CK824_14300	COG2885	chlorophyll binding
CK824_14305	COG0204	Acyl-transferase
CK824_14320	COG2894	cell division
CK824_14345	COG1280	lysine exporter protein (LysE YggA)
CK824_14350	COG1674	ftsk spoiiie
CK824_14350	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK824_14355	COG0492	ferredoxin-NADP+ reductase activity
CK824_14360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CK824_14370	COG0456	acetyltransferase
CK824_14430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK824_14430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CK824_14450	COG1012	belongs to the aldehyde dehydrogenase family
CK824_14470	COG0473	3-isopropylmalate dehydrogenase activity
CK824_14475	COG0583	DNA-binding transcription factor activity
CK824_14495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK824_14520	COG0564	pseudouridine synthase activity
CK824_14530	COG0358	DNA primase activity
CK824_14545	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CK824_14575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK824_14605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK824_14615	COG0351	phosphomethylpyrimidine kinase
CK824_14615	COG0352	thiamine-phosphate diphosphorylase activity
CK824_14615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK824_14620	COG1652	LysM domain
CK824_14645	COG1399	metal-binding, possibly nucleic acid-binding protein
CK824_14650	COG3101	peptidyl-lysine hydroxylation
CK824_14655	COG0009	L-threonylcarbamoyladenylate synthase
CK824_14660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CK824_14665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CK824_14680	COG4106	trans-aconitate 2-methyltransferase activity
CK824_14695	COG2226	methyltransferase
CK824_14695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_14695	COG0596	Alpha beta hydrolase
CK824_14700	COG1877	trehalose-phosphatase activity
CK824_14705	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CK824_14710	COG2223	nitrite transmembrane transporter activity
CK824_14730	COG1196	nuclear chromosome segregation
CK824_14740	COG0730	response to heat
CK824_14755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK824_14765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK824_14820	COG0489	protein tyrosine kinase activity
CK824_14830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_14830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_14860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CK824_14865	COG2081	HI0933 family
CK824_14875	COG0668	transmembrane transport
CK824_14895	COG0583	DNA-binding transcription factor activity
CK824_14915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK824_14920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK824_14950	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CK824_14985	COG2205	protein histidine kinase activity
CK824_14990	COG0745	RESPONSE REGULATOR receiver
CK824_15010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK824_15020	COG2205	protein histidine kinase activity
CK824_15090	COG4993	Dehydrogenase
CK824_15110	COG0384	phenazine biosynthesis protein PhzF
CK824_15140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_15145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CK824_15155	COG0583	DNA-binding transcription factor activity
CK824_15175	COG1473	amidohydrolase
CK824_15185	COG0583	DNA-binding transcription factor activity
CK824_15205	COG0583	DNA-binding transcription factor activity
CK824_15210	COG1053	succinate dehydrogenase
CK824_15220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CK824_15225	COG2814	Major facilitator Superfamily
CK824_15230	COG1960	acyl-CoA dehydrogenase activity
CK824_15235	COG0583	DNA-binding transcription factor activity
CK824_15240	COG1063	alcohol dehydrogenase
CK824_15270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CK824_15275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CK824_15280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK824_15295	COG3667	copper resistance
CK824_15300	COG2132	Multicopper oxidase
CK824_15310	COG0561	phosphatase activity
CK824_15315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK824_15340	COG1214	PFAM Peptidase M22, glycoprotease
CK824_15390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK824_15400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK824_15405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CK824_15410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK824_15470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK824_15480	COG1846	Transcriptional regulator
CK824_15485	COG1764	response to oxidative stress
CK824_15535	COG0037	tRNA processing
CK824_15545	COG0248	Ppx GppA phosphatase
CK824_15575	COG0072	phenylalanine-tRNA ligase activity
CK824_15600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CK824_15615	COG1238	metal cluster binding
CK824_15620	COG0625	glutathione transferase activity
CK824_15640	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_15645	COG3028	Belongs to the UPF0307 family
CK824_15650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK824_15670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK824_15675	COG0617	tRNA 3'-terminal CCA addition
CK824_15680	COG1555	photosystem II stabilization
CK824_15685	COG3956	TIGRFAM MazG family protein
CK824_15695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK824_15715	COG2205	protein histidine kinase activity
CK824_15715	COG5002	protein histidine kinase activity
CK824_15715	COG0784	Response regulator, receiver
CK824_15720	COG1024	Enoyl-CoA hydratase
CK824_15725	COG2084	Dehydrogenase
CK824_15730	COG3622	Belongs to the hyi family
CK824_15745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CK824_15750	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CK824_15755	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CK824_15760	COG0697	spore germination
CK824_15770	COG2814	Major facilitator Superfamily
CK824_15775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK824_15785	COG0583	DNA-binding transcription factor activity
CK824_15795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK824_15810	COG0084	hydrolase, TatD family'
CK824_15825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CK824_15860	COG0440	acetolactate synthase activity
CK824_15865	COG0028	Belongs to the TPP enzyme family
CK824_15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_15895	COG1136	(ABC) transporter
CK824_15895	COG0577	efflux transmembrane transporter activity
CK824_15900	COG1538	Outer membrane efflux protein
CK824_15915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CK824_15920	COG1162	GTPase activity
CK824_15930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK824_15950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK824_15955	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_15995	COG2986	histidine ammonia-lyase
CK824_16010	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_16020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK824_16025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK824_16065	COG1426	Protein conserved in bacteria
CK824_16100	COG0793	Belongs to the peptidase S41A family
CK824_16115	COG2267	carboxylic ester hydrolase activity
CK824_16125	COG1012	belongs to the aldehyde dehydrogenase family
CK824_16130	COG3265	gluconokinase activity
CK824_16140	COG0800	Aldolase
CK824_16150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK824_16155	COG0857	belongs to the CobB CobQ family
CK824_16155	COG0280	phosphate acetyltransferase
CK824_16160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CK824_16160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CK824_16180	COG0740	serine-type endopeptidase activity
CK824_16190	COG4774	siderophore transport
CK824_16200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK824_16210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_16210	COG2813	Specifically methylates the guanine in position
CK824_16310	COG0788	formyltetrahydrofolate deformylase activity
CK824_16325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CK824_16330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CK824_16335	COG4651	solute:proton antiporter activity
CK824_16335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_16355	COG0724	RNA recognition motif
CK824_16360	COG0210	DNA helicase
CK824_16385	COG1733	regulation of RNA biosynthetic process
CK824_16405	COG1280	lysine exporter protein (LysE YggA)
CK824_16410	COG1560	Kdo2-lipid A biosynthetic process
CK824_16420	COG1301	dicarboxylic acid transport
CK824_16475	COG0473	3-isopropylmalate dehydrogenase activity
CK824_16540	COG0583	DNA-binding transcription factor activity
CK824_16550	COG0625	glutathione transferase activity
CK824_16555	COG2378	regulation of single-species biofilm formation
CK824_16560	COG0546	phosphoglycolate phosphatase activity
CK824_16575	COG1530	ribonuclease E activity
CK824_16595	COG0583	DNA-binding transcription factor activity
CK824_16600	COG4221	oxidoreductase activity
CK824_16605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK824_16615	COG0534	Mate efflux family protein
CK824_16630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CK824_16670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CK824_16675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_16690	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK824_16700	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CK824_16700	COG0644	oxidoreductase
CK824_16705	COG0425	Belongs to the sulfur carrier protein TusA family
CK824_16710	COG4535	Mg2 and Co2 transporter CorC
CK824_16720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_16740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK824_16745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_16745	COG0475	glutathione-regulated potassium exporter activity
CK824_16750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CK824_16760	COG0484	heat shock protein binding
CK824_16765	COG0789	Transcriptional regulator
CK824_16770	COG0598	Magnesium transport protein CorA
CK824_16790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK824_16795	COG1074	ATP-dependent DNA helicase activity
CK824_16800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CK824_16820	COG2226	methyltransferase
CK824_16835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_16840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK824_16855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK824_16855	COG2111	Na H antiporter
CK824_16860	COG1006	Multisubunit Na H antiporter MnhC subunit
CK824_16865	COG0651	ATP synthesis coupled electron transport
CK824_16875	COG2212	antiporter activity
CK824_16895	COG0195	Participates in both transcription termination and antitermination
CK824_16945	COG0237	dephospho-CoA kinase activity
CK824_16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK824_16970	COG0497	DNA recombination
CK824_16980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CK824_17010	COG2169	Transcriptional regulator
CK824_17010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK824_17015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK824_17085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK824_17100	COG0326	Molecular chaperone. Has ATPase activity
CK824_17115	COG2056	Na+-H+ antiporter family
CK824_17120	COG0596	Alpha beta hydrolase
CK824_17215	COG0546	phosphoglycolate phosphatase activity
CK824_17220	COG1716	ATPase activity
CK824_17265	COG0181	hydroxymethylbilane synthase activity
CK824_17275	COG3275	phosphorelay sensor kinase activity
CK824_17295	COG1538	Outer membrane efflux protein
CK824_17300	COG0697	spore germination
CK824_17325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CK824_17330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK824_17335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK824_17340	COG0772	Belongs to the SEDS family
CK824_17365	COG4974	Belongs to the 'phage' integrase family
CK824_17370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_17380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK824_17390	COG2197	response regulator
CK824_17405	COG0793	Belongs to the peptidase S41A family
CK824_17410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CK824_17415	COG0795	lipopolysaccharide-transporting ATPase activity
CK824_17455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK824_17455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK824_17465	COG0004	ammonium transporteR
CK824_17470	COG0347	Belongs to the P(II) protein family
CK824_17480	COG0606	chelatase, subunit chli
CK824_17535	COG0659	secondary active sulfate transmembrane transporter activity
CK824_17540	COG0589	response to stress
CK824_17570	COG0606	chelatase, subunit chli
CK824_17575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_17585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_17600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CK824_17615	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_17625	COG0477	Major facilitator Superfamily
CK824_17630	COG2860	membrane
CK824_17640	COG1253	flavin adenine dinucleotide binding
CK824_17660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK824_17695	COG0655	NAD(P)H dehydrogenase (quinone) activity
CK824_17705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK824_17775	COG0758	DNA mediated transformation
CK824_17785	COG0697	spore germination
CK824_17790	COG1309	transcriptional regulator
CK824_17805	COG0386	Belongs to the glutathione peroxidase family
CK824_17870	COG1121	(ABC) transporter
CK824_17875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK824_17880	COG1280	lysine exporter protein (LysE YggA)
CK824_17885	COG2837	iron assimilation
CK824_17895	COG0281	malic enzyme
CK824_17940	COG0519	Catalyzes the synthesis of GMP from XMP
CK824_17940	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK824_17945	COG4399	Belongs to the UPF0754 family
CK824_17950	COG2259	Doxx family
CK824_17955	COG0586	Pfam SNARE associated Golgi protein
CK824_17970	COG1192	Involved in chromosome partitioning
CK824_17980	COG0271	Belongs to the BolA IbaG family
CK824_18000	COG2267	carboxylic ester hydrolase activity
CK824_18020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK824_18020	COG3321	synthase
CK824_18020	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CK824_18020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK824_18025	COG1960	acyl-CoA dehydrogenase activity
CK824_18035	COG2197	response regulator
CK824_18045	COG3916	Acyl-homoserine-lactone synthase
CK824_18050	COG0477	Major facilitator Superfamily
CK824_18055	COG1024	Enoyl-CoA hydratase
CK824_18060	COG1024	Enoyl-CoA hydratase
CK824_18065	COG1960	acyl-CoA dehydrogenase activity
CK824_18070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_18090	COG1113	amino acid transport
CK824_18095	COG1113	amino acid transport
CK824_18100	COG0251	oxidation-reduction process
CK824_18115	COG1522	sequence-specific DNA binding
CK824_18140	COG0564	pseudouridine synthase activity
CK824_18205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK824_18220	COG1802	Transcriptional regulator
CK824_18230	COG1448	Aminotransferase
CK824_18235	COG0277	FAD linked oxidase domain protein
CK824_18245	COG2186	Transcriptional regulator
CK824_18255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK824_18260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK824_18275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK824_18285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK824_18295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK824_18300	COG0438	transferase activity, transferring glycosyl groups
CK824_18320	COG1216	Glycosyl transferase, family 2
CK824_18325	COG5039	Polysaccharide pyruvyl transferase
CK824_18335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK824_18340	COG1596	polysaccharide export
CK824_18365	COG0728	peptidoglycan biosynthetic process
CK824_18370	COG3023	N-Acetylmuramoyl-L-alanine amidase
CK824_18430	COG0546	phosphoglycolate phosphatase activity
CK824_18435	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_18455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_18460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_18465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_18470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_18475	COG1116	anion transmembrane transporter activity
CK824_18480	COG1309	transcriptional regulator
CK824_18485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK824_18495	COG0196	riboflavin kinase activity
CK824_18500	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CK824_18510	COG1047	Peptidyl-prolyl cis-trans
CK824_18550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK824_18605	COG2951	lytic endotransglycosylase activity
CK824_18610	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK824_18630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK824_18640	COG0671	phosphoesterase, PA-phosphatase related
CK824_18645	COG0861	Integral membrane protein TerC family
CK824_18655	COG0754	glutathionylspermidine amidase activity
CK824_18665	COG0402	S-adenosylhomocysteine deaminase activity
CK824_18680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_18685	COG1230	cation diffusion facilitator family transporter
CK824_18700	COG0706	membrane insertase activity
CK824_18715	COG0230	Belongs to the bacterial ribosomal protein bL34 family