locus-tag	class	description
HUF98_00010	COG0592	DNA-directed DNA polymerase activity
HUF98_00020	COG0187	DNA topoisomerase II activity
HUF98_00030	COG0586	Pfam SNARE associated Golgi protein
HUF98_00035	COG0488	(ABC) transporter
HUF98_00060	COG0596	Alpha beta hydrolase
HUF98_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUF98_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUF98_00100	COG0625	glutathione transferase activity
HUF98_00110	COG0733	neurotransmitter:sodium symporter activity
HUF98_00145	COG0583	DNA-binding transcription factor activity
HUF98_00150	COG2233	PERMEase
HUF98_00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_00200	COG2814	Major facilitator Superfamily
HUF98_00205	COG0656	L-ascorbic acid biosynthetic process
HUF98_00210	COG0583	DNA-binding transcription factor activity
HUF98_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_00230	COG1064	alcohol dehydrogenase
HUF98_00235	COG2818	Glycosylase
HUF98_00250	COG1194	a g-specific adenine glycosylase
HUF98_00270	COG2983	Belongs to the UPF0260 family
HUF98_00275	COG2133	pyrroloquinoline quinone binding
HUF98_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUF98_00285	COG2116	formate transmembrane transporter activity
HUF98_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_00310	COG1335	isochorismatase
HUF98_00315	COG0385	Bile acid
HUF98_00320	COG0534	Mate efflux family protein
HUF98_00325	COG1683	Conserved Protein
HUF98_00345	COG0625	glutathione transferase activity
HUF98_00355	COG1113	amino acid transport
HUF98_00365	COG0523	cobalamin synthesis protein
HUF98_00375	COG2188	Transcriptional regulator
HUF98_00405	COG0010	Belongs to the arginase family
HUF98_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUF98_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUF98_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUF98_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUF98_00485	COG0753	catalase activity
HUF98_00535	COG0534	Mate efflux family protein
HUF98_00540	COG0436	Aminotransferase
HUF98_00545	COG2733	membrane
HUF98_00560	COG2918	glutathione biosynthetic process
HUF98_00625	COG3150	esterase
HUF98_00635	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_00640	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HUF98_00650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_00660	COG2233	PERMEase
HUF98_00665	COG2351	hydroxyisourate hydrolase activity
HUF98_00700	COG3706	GGDEF domain
HUF98_00715	COG1393	Belongs to the ArsC family
HUF98_00720	COG0708	Exodeoxyribonuclease III
HUF98_00760	COG0189	ligase activity
HUF98_00780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUF98_00790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUF98_00805	COG4942	peptidase
HUF98_00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUF98_00825	COG2119	membrane
HUF98_00830	COG4774	siderophore transport
HUF98_00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_00835	COG0426	domain, Protein
HUF98_00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUF98_00880	COG1902	pentaerythritol trinitrate reductase activity
HUF98_00885	COG1519	Transferase
HUF98_00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUF98_00895	COG0668	transmembrane transport
HUF98_00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_00910	COG1335	isochorismatase
HUF98_00915	COG1522	sequence-specific DNA binding
HUF98_00940	COG0784	Response regulator, receiver
HUF98_00940	COG2198	Histidine kinase
HUF98_00940	COG2205	protein histidine kinase activity
HUF98_00945	COG3162	membrane
HUF98_00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUF98_00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_00980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUF98_00985	COG1309	transcriptional regulator
HUF98_01005	COG0351	phosphomethylpyrimidine kinase
HUF98_01005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUF98_01005	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_01015	COG2814	Major facilitator Superfamily
HUF98_01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUF98_01040	COG1113	amino acid transport
HUF98_01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUF98_01055	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_01065	COG1335	isochorismatase
HUF98_01110	COG2814	Major facilitator Superfamily
HUF98_01115	COG0583	DNA-binding transcription factor activity
HUF98_01165	COG0667	Aldo Keto reductase
HUF98_01195	COG1733	regulation of RNA biosynthetic process
HUF98_01200	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_01210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUF98_01265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUF98_01280	COG2329	Antibiotic biosynthesis monooxygenase
HUF98_01295	COG1132	(ABC) transporter
HUF98_01315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUF98_01345	COG0427	acetyl-CoA hydrolase
HUF98_01370	COG0659	secondary active sulfate transmembrane transporter activity
HUF98_01375	COG4221	oxidoreductase activity
HUF98_01385	COG0488	(ABC) transporter
HUF98_01450	COG0833	amino acid
HUF98_01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HUF98_01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUF98_01515	COG2226	methyltransferase
HUF98_01565	COG0067	glutamate synthase
HUF98_01565	COG0069	glutamate synthase activity
HUF98_01565	COG0070	glutamate synthase
HUF98_01570	COG0493	'glutamate synthase
HUF98_01580	COG1704	LemA family
HUF98_01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUF98_01605	COG3307	-O-antigen
HUF98_01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUF98_01640	COG0194	GDP metabolic process
HUF98_01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUF98_01710	COG5380	lipid catabolic process
HUF98_01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUF98_01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUF98_01745	COG0277	FAD linked oxidase domain protein
HUF98_01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUF98_01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_01775	COG1289	transmembrane transporter activity
HUF98_01785	COG0628	permease
HUF98_01790	COG1192	Involved in chromosome partitioning
HUF98_01830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUF98_01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUF98_01845	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_01885	COG0583	DNA-binding transcription factor activity
HUF98_01930	COG0517	IMP dehydrogenase activity
HUF98_01935	COG1983	PspC domain protein
HUF98_01945	COG1960	acyl-CoA dehydrogenase activity
HUF98_01960	COG0408	coproporphyrinogen oxidase activity
HUF98_01980	COG0513	Belongs to the DEAD box helicase family
HUF98_01990	COG1127	ABC transporter
HUF98_01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUF98_02005	COG2854	intermembrane phospholipid transfer
HUF98_02015	COG0598	Magnesium transport protein CorA
HUF98_02025	COG0494	nUDIX hydrolase
HUF98_02030	COG1040	competence protein
HUF98_02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUF98_02055	COG1946	Acyl-CoA thioesterase
HUF98_02060	COG1301	dicarboxylic acid transport
HUF98_02075	COG1959	2 iron, 2 sulfur cluster binding
HUF98_02080	COG1017	nitric oxide dioxygenase activity
HUF98_02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_02090	COG0433	COG0433 Predicted ATPase
HUF98_02095	COG0626	cystathionine gamma-synthase activity
HUF98_02250	COG1960	acyl-CoA dehydrogenase activity
HUF98_02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HUF98_02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HUF98_02290	COG0339	signal peptide processing
HUF98_02295	COG0557	exoribonuclease II activity
HUF98_02340	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUF98_02345	COG2169	Transcriptional regulator
HUF98_02350	COG0697	spore germination
HUF98_02355	COG1295	ribonuclease BN
HUF98_02390	COG1702	phosphate starvation-inducible protein PhoH
HUF98_02400	COG0739	heme binding
HUF98_02400	COG0741	lytic transglycosylase activity
HUF98_02400	COG1196	nuclear chromosome segregation
HUF98_02430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HUF98_02435	COG1183	phosphatidylcholine synthase activity
HUF98_02480	COG1960	acyl-CoA dehydrogenase activity
HUF98_02485	COG1309	transcriptional regulator
HUF98_02500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUF98_02505	COG1960	acyl-CoA dehydrogenase activity
HUF98_02525	COG2969	positive regulation of protein catabolic process
HUF98_02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUF98_02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUF98_02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUF98_02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUF98_02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUF98_02590	COG1408	metallophosphoesterase
HUF98_02600	COG2199	diguanylate cyclase activity
HUF98_02660	COG1607	acyl-coa hydrolase
HUF98_02690	COG2350	Protein conserved in bacteria
HUF98_02700	COG0613	PHP domain protein
HUF98_02705	COG3781	membrane
HUF98_02715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUF98_02720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUF98_02730	COG1862	Preprotein translocase
HUF98_02765	COG2205	protein histidine kinase activity
HUF98_02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUF98_02790	COG0726	polysaccharide deacetylase
HUF98_02795	COG0463	Glycosyl transferase, family 2
HUF98_02800	COG0438	transferase activity, transferring glycosyl groups
HUF98_02815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUF98_02865	COG1960	acyl-CoA dehydrogenase activity
HUF98_02870	COG1960	acyl-CoA dehydrogenase activity
HUF98_02880	COG2205	protein histidine kinase activity
HUF98_02885	COG0745	RESPONSE REGULATOR receiver
HUF98_02890	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HUF98_02905	COG0584	glycerophosphoryl diester phosphodiesterase
HUF98_02910	COG2096	Adenosyltransferase
HUF98_02915	COG4206	TonB-dependent receptor
HUF98_02960	COG0285	dihydrofolate synthase activity
HUF98_02980	COG0450	alkyl hydroperoxide reductase
HUF98_02995	COG0477	Major facilitator Superfamily
HUF98_03000	COG1272	protein, Hemolysin III
HUF98_03030	COG0183	Belongs to the thiolase family
HUF98_03035	COG2207	Transcriptional regulator
HUF98_03055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_03075	COG0183	Belongs to the thiolase family
HUF98_03085	COG2885	chlorophyll binding
HUF98_03085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HUF98_03095	COG1690	Belongs to the RtcB family
HUF98_03100	COG0833	amino acid
HUF98_03110	COG2233	PERMEase
HUF98_03115	COG1217	gtp-binding protein TYPA
HUF98_03140	COG2094	Belongs to the DNA glycosylase MPG family
HUF98_03145	COG4772	TonB-dependent receptor
HUF98_03150	COG1902	pentaerythritol trinitrate reductase activity
HUF98_03165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_03170	COG0354	folic acid binding
HUF98_03180	COG3189	MarR family transcriptional regulator
HUF98_03185	COG2824	Alkylphosphonate utilization operon protein PhnA
HUF98_03190	COG3422	double-strand break repair
HUF98_03230	COG0840	transmembrane signaling receptor activity
HUF98_03250	COG5510	response to toxic substance
HUF98_03260	COG2832	Protein of unknown function (DUF454)
HUF98_03265	COG1376	ErfK ybiS ycfS ynhG family protein
HUF98_03305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUF98_03315	COG1289	transmembrane transporter activity
HUF98_03320	COG2814	Major facilitator Superfamily
HUF98_03340	COG1115	amino acid carrier protein
HUF98_03345	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUF98_03350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUF98_03355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HUF98_03360	COG3590	peptidase
HUF98_03385	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUF98_03395	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUF98_03400	COG1077	Cell shape determining protein MreB Mrl
HUF98_03405	COG1792	Involved in formation and maintenance of cell shape
HUF98_03410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUF98_03415	COG0424	maF-like protein
HUF98_03420	COG1530	ribonuclease E activity
HUF98_03430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_03440	COG0560	Phosphoserine phosphatase
HUF98_03450	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_03475	COG2207	Transcriptional regulator
HUF98_03535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_03735	COG0582	viral genome integration into host DNA
HUF98_03745	COG1113	amino acid transport
HUF98_03750	COG2828	Protein conserved in bacteria
HUF98_03755	COG0142	geranyltranstransferase activity
HUF98_03760	COG2315	Protein conserved in bacteria
HUF98_03775	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUF98_03795	COG2194	sulfuric ester hydrolase activity
HUF98_03800	COG0745	RESPONSE REGULATOR receiver
HUF98_03805	COG0642	Histidine kinase
HUF98_03815	COG0004	ammonium transporteR
HUF98_03820	COG0583	DNA-binding transcription factor activity
HUF98_03840	COG0525	valine-tRNA ligase activity
HUF98_03850	COG0525	valine-tRNA ligase activity
HUF98_03860	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_03870	COG0393	Putative heavy-metal-binding
HUF98_03875	COG0393	Putative heavy-metal-binding
HUF98_03880	COG1538	Outer membrane efflux protein
HUF98_03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_03895	COG0671	phosphoesterase, PA-phosphatase related
HUF98_03925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HUF98_03940	COG1648	precorrin-2 dehydrogenase activity
HUF98_03940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUF98_03945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUF98_03950	COG1733	regulation of RNA biosynthetic process
HUF98_03960	COG0531	amino acid
HUF98_03975	COG0321	lipoyl(octanoyl) transferase activity
HUF98_03980	COG2921	Belongs to the UPF0250 family
HUF98_04020	COG2009	succinate dehydrogenase
HUF98_04025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HUF98_04030	COG1053	succinate dehydrogenase
HUF98_04035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUF98_04060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_04080	COG2354	Protein conserved in bacteria
HUF98_04085	COG2321	neutral zinc metallopeptidase
HUF98_04105	COG2843	Capsule synthesis protein
HUF98_04120	COG0589	response to stress
HUF98_04130	COG0251	oxidation-reduction process
HUF98_04135	COG1309	transcriptional regulator
HUF98_04150	COG0505	Belongs to the CarA family
HUF98_04180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUF98_04185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUF98_04245	COG0477	Major facilitator Superfamily
HUF98_04250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUF98_04265	COG1597	lipid kinase activity
HUF98_04270	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUF98_04290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_04295	COG0584	glycerophosphoryl diester phosphodiesterase
HUF98_04315	COG0741	lytic transglycosylase activity
HUF98_04335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUF98_04350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_04375	COG3811	Belongs to the UPF0386 family
HUF98_04395	COG0778	Nitroreductase
HUF98_04410	COG1929	Belongs to the glycerate kinase type-1 family
HUF98_04415	COG0243	molybdopterin cofactor binding
HUF98_04420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUF98_04425	COG3339	Conserved Protein
HUF98_04435	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HUF98_04450	COG1115	amino acid carrier protein
HUF98_04455	COG1113	amino acid transport
HUF98_04465	COG0019	diaminopimelate decarboxylase activity
HUF98_04475	COG1280	lysine exporter protein (LysE YggA)
HUF98_04480	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HUF98_04510	COG0463	Glycosyl transferase, family 2
HUF98_04530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_04565	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUF98_04570	COG1136	(ABC) transporter
HUF98_04575	COG0658	competence protein
HUF98_04575	COG2333	competence protein COMEC
HUF98_04585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUF98_04585	COG0616	signal peptide processing
HUF98_04590	COG0596	Alpha beta hydrolase
HUF98_04595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUF98_04605	COG0628	permease
HUF98_04640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUF98_04660	COG0823	Involved in the tonB-independent uptake of proteins
HUF98_04680	COG0824	Thioesterase
HUF98_04685	COG1473	amidohydrolase
HUF98_04705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUF98_04705	COG0047	phosphoribosylformylglycinamidine synthase activity
HUF98_04710	COG2814	Major facilitator Superfamily
HUF98_04720	COG1024	Enoyl-CoA hydratase
HUF98_04725	COG1051	belongs to the nudix hydrolase family
HUF98_04725	COG1056	cytidyltransferase-related domain
HUF98_04735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUF98_04750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUF98_04765	COG4625	pathogenesis
HUF98_04770	COG0583	DNA-binding transcription factor activity
HUF98_04775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HUF98_04780	COG4208	sulfate ABC transporter
HUF98_04785	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HUF98_04795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HUF98_04800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUF98_04805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUF98_04825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUF98_04835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUF98_04845	COG0681	Belongs to the peptidase S26 family
HUF98_04860	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUF98_04870	COG1381	Involved in DNA repair and RecF pathway recombination
HUF98_04875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUF98_04885	COG4221	oxidoreductase activity
HUF98_04915	COG0436	Aminotransferase
HUF98_04935	COG0556	nucleotide-excision repair
HUF98_04990	COG2070	2-Nitropropane dioxygenase
HUF98_05020	COG1215	transferase activity, transferring glycosyl groups
HUF98_05035	COG0415	Belongs to the DNA photolyase family
HUF98_05045	COG1252	NADH dehydrogenase
HUF98_05050	COG1686	Belongs to the peptidase S11 family
HUF98_05065	COG1187	pseudouridine synthase activity
HUF98_05090	COG0477	Major facilitator Superfamily
HUF98_05095	COG0583	DNA-binding transcription factor activity
HUF98_05100	COG1823	symporter activity
HUF98_05110	COG0612	Peptidase, M16
HUF98_05135	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_05170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_05180	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_05195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUF98_05200	COG0076	glutamate decarboxylase activity
HUF98_05210	COG1522	sequence-specific DNA binding
HUF98_05215	COG3961	Belongs to the TPP enzyme family
HUF98_05220	COG1113	amino acid transport
HUF98_05225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUF98_05230	COG0573	inorganic phosphate transmembrane transporter activity
HUF98_05240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUF98_05245	COG0616	signal peptide processing
HUF98_05280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUF98_05285	COG1686	Belongs to the peptidase S11 family
HUF98_05310	COG0583	DNA-binding transcription factor activity
HUF98_05315	COG1067	ATP-dependent peptidase activity
HUF98_05320	COG2211	Major facilitator Superfamily
HUF98_05340	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HUF98_05360	COG1966	Carbon starvation protein
HUF98_05365	COG2879	small protein
HUF98_05395	COG1741	Belongs to the pirin family
HUF98_05405	COG2964	Protein conserved in bacteria
HUF98_05420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_05425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUF98_05430	COG4605	iron ion homeostasis
HUF98_05435	COG4604	ABC transporter, ATP-binding protein
HUF98_05440	COG4607	ABC-type enterochelin transport system periplasmic component
HUF98_05445	COG4774	siderophore transport
HUF98_05455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUF98_05460	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUF98_05465	COG1535	isochorismatase
HUF98_05465	COG3433	isochorismatase activity
HUF98_05475	COG1132	(ABC) transporter
HUF98_05480	COG1132	(ABC) transporter
HUF98_05485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUF98_05495	COG1169	isochorismate synthase
HUF98_05510	COG3739	integral membrane protein
HUF98_05530	COG0302	gtp cyclohydrolase
HUF98_05540	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUF98_05575	COG0512	Glutamine amidotransferase of anthranilate synthase
HUF98_05590	COG0174	glutamine synthetase
HUF98_05600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUF98_05635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUF98_05640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUF98_05645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUF98_05665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUF98_05670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUF98_05675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUF98_05690	COG1960	acyl-CoA dehydrogenase activity
HUF98_05695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUF98_05700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_05710	COG2223	nitrite transmembrane transporter activity
HUF98_05720	COG0024	Methionine aminopeptidase
HUF98_05725	COG0052	Belongs to the universal ribosomal protein uS2 family
HUF98_05740	COG2207	Transcriptional regulator
HUF98_05765	COG2951	lytic endotransglycosylase activity
HUF98_05770	COG0772	Belongs to the SEDS family
HUF98_05785	COG0842	Transport permease protein
HUF98_05790	COG1131	(ABC) transporter
HUF98_05835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_05850	COG4215	(ABC) transporter
HUF98_05855	COG4160	amino acid transport
HUF98_05860	COG4598	ABC transporter
HUF98_05870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_05875	COG0826	peptidase U32
HUF98_05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_05895	COG1720	tRNA m6t6A37 methyltransferase activity
HUF98_05905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUF98_05920	COG0642	Histidine kinase
HUF98_05930	COG0494	nUDIX hydrolase
HUF98_05940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUF98_05945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUF98_05950	COG3139	Protein of unknown function (DUF1315)
HUF98_05955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUF98_05960	COG1301	dicarboxylic acid transport
HUF98_05965	COG1960	acyl-CoA dehydrogenase activity
HUF98_05970	COG2819	hydrolase of the alpha beta superfamily
HUF98_05980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUF98_05990	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUF98_05995	COG1234	tRNA 3'-trailer cleavage
HUF98_06025	COG2363	Small membrane protein
HUF98_06045	COG0513	Belongs to the DEAD box helicase family
HUF98_06055	COG0778	Nitroreductase
HUF98_06085	COG1286	toxin biosynthetic process
HUF98_06110	COG4783	chaperone-mediated protein folding
HUF98_06115	COG1610	YqeY-like protein
HUF98_06145	COG0515	serine threonine protein kinase
HUF98_06145	COG2815	serine threonine protein kinase
HUF98_06215	COG3111	PFAM Bacterial OB fold (BOF) protein
HUF98_06240	COG3243	poly(R)-hydroxyalkanoic acid synthase
HUF98_06245	COG0786	glutamate:sodium symporter activity
HUF98_06255	COG2186	Transcriptional regulator
HUF98_06305	COG0477	Major facilitator Superfamily
HUF98_06330	COG2985	domain, Protein
HUF98_06340	COG2995	paraquat-inducible protein a
HUF98_06345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUF98_06345	COG3008	intermembrane lipid transfer
HUF98_06355	COG2351	hydroxyisourate hydrolase activity
HUF98_06395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUF98_06405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUF98_06410	COG0642	Histidine kinase
HUF98_06415	COG0745	RESPONSE REGULATOR receiver
HUF98_06435	COG1794	racemase activity, acting on amino acids and derivatives
HUF98_06465	COG1301	dicarboxylic acid transport
HUF98_06475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_06480	COG2011	ABC-type metal ion transport system permease component
HUF98_06485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUF98_06490	COG1464	Belongs to the NlpA lipoprotein family
HUF98_06495	COG0151	Belongs to the GarS family
HUF98_06500	COG0138	bifunctional purine biosynthesis protein purh
HUF98_06505	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HUF98_06535	COG2308	Evidence 4 Homologs of previously reported genes of
HUF98_06545	COG1305	Transglutaminase-like
HUF98_06555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUF98_06560	COG0305	Participates in initiation and elongation during chromosome replication
HUF98_06585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUF98_06595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUF98_06600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUF98_06625	COG1649	PFAM Uncharacterised BCR, COG1649
HUF98_06625	COG0726	polysaccharide deacetylase
HUF98_06630	COG1215	transferase activity, transferring glycosyl groups
HUF98_06635	COG3658	cytochrome
HUF98_06645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_06660	COG0583	DNA-binding transcription factor activity
HUF98_06690	COG1960	acyl-CoA dehydrogenase activity
HUF98_06695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_06700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_06725	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUF98_06730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUF98_06740	COG2205	protein histidine kinase activity
HUF98_06745	COG0745	RESPONSE REGULATOR receiver
HUF98_06750	COG0174	glutamine synthetase
HUF98_06770	COG0729	surface antigen
HUF98_06795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUF98_06800	COG2814	Major facilitator Superfamily
HUF98_06815	COG0583	DNA-binding transcription factor activity
HUF98_06830	COG1187	pseudouridine synthase activity
HUF98_06850	COG0802	atpase or kinase
HUF98_06855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HUF98_06865	COG1923	regulation of RNA biosynthetic process
HUF98_06870	COG0697	spore germination
HUF98_06895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUF98_06900	COG0519	Catalyzes the synthesis of GMP from XMP
HUF98_06900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUF98_06905	COG4302	ethanolamine ammonia-lyase activity
HUF98_06910	COG4303	Ethanolamine ammonia lyase large subunit
HUF98_06915	COG0531	amino acid
HUF98_06935	COG1454	alcohol dehydrogenase
HUF98_06940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUF98_06965	COG0308	aminopeptidase N
HUF98_07005	COG1605	Chorismate mutase
HUF98_07030	COG0668	transmembrane transport
HUF98_07060	COG4773	Receptor
HUF98_07080	COG0488	(ABC) transporter
HUF98_07085	COG0589	response to stress
HUF98_07110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUF98_07120	COG3135	benzoate transporter
HUF98_07125	COG1522	sequence-specific DNA binding
HUF98_07135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUF98_07140	COG0583	DNA-binding transcription factor activity
HUF98_07150	COG0183	Belongs to the thiolase family
HUF98_07160	COG2030	dehydratase
HUF98_07165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUF98_07180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUF98_07195	COG0824	Thioesterase
HUF98_07200	COG1454	alcohol dehydrogenase
HUF98_07210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUF98_07230	COG0069	glutamate synthase activity
HUF98_07520	COG1598	PFAM Uncharacterised protein family UPF0150
HUF98_07620	COG2814	Major facilitator Superfamily
HUF98_07635	COG0511	ligase activity, forming carbon-carbon bonds
HUF98_07655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_07655	COG1116	anion transmembrane transporter activity
HUF98_07660	COG0745	RESPONSE REGULATOR receiver
HUF98_07670	COG2146	nitrite reductase [NAD(P)H] activity
HUF98_07670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_07675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_07680	COG0243	molybdopterin cofactor binding
HUF98_07690	COG0243	molybdopterin cofactor binding
HUF98_07695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUF98_07710	COG0315	cyclic pyranopterin monophosphate synthase activity
HUF98_07710	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUF98_07715	COG0303	'Molybdopterin
HUF98_07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_07730	COG0697	spore germination
HUF98_07750	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HUF98_07755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUF98_07810	COG2204	response regulator
HUF98_07815	COG3852	Histidine kinase
HUF98_07840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUF98_07845	COG0575	Belongs to the CDS family
HUF98_07860	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUF98_07880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUF98_07895	COG2137	regulation of response to DNA damage stimulus
HUF98_07905	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUF98_07910	COG1011	Hydrolase
HUF98_07945	COG1522	sequence-specific DNA binding
HUF98_07955	COG1113	amino acid transport
HUF98_07970	COG0659	secondary active sulfate transmembrane transporter activity
HUF98_07975	COG2135	peptidase activity
HUF98_07990	COG5001	Diguanylate cyclase
HUF98_07990	COG3300	MHYT domain
HUF98_08115	COG2369	cell adhesion
HUF98_08120	COG4383	Mu-like prophage protein gp29
HUF98_08140	COG4373	Mu-like prophage FluMu protein gp28
HUF98_08200	COG0776	regulation of translation
HUF98_08260	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUF98_08260	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUF98_08260	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HUF98_08265	COG1105	Belongs to the carbohydrate kinase PfkB family
HUF98_08270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUF98_08270	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUF98_08300	COG0024	Methionine aminopeptidase
HUF98_08305	COG0583	DNA-binding transcription factor activity
HUF98_08315	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HUF98_08320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUF98_08325	COG0516	GMP reductase activity
HUF98_08325	COG0517	IMP dehydrogenase activity
HUF98_08355	COG0552	protein localization to endoplasmic reticulum
HUF98_08365	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HUF98_08380	COG4890	Cyd operon protein YbgT
HUF98_08385	COG1294	oxidase, subunit
HUF98_08400	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUF98_08410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUF98_08415	COG4774	siderophore transport
HUF98_08430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUF98_08435	COG0569	domain protein
HUF98_08440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUF98_08470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HUF98_08475	COG0542	response to heat
HUF98_08500	COG1902	pentaerythritol trinitrate reductase activity
HUF98_08500	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_08545	COG2323	membrane
HUF98_08550	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HUF98_08560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_08565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_08570	COG0183	Belongs to the thiolase family
HUF98_08575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUF98_08580	COG0596	Alpha beta hydrolase
HUF98_08585	COG2271	Major facilitator Superfamily
HUF98_08590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUF98_08595	COG3485	protocatechuate 3,4-dioxygenase
HUF98_08600	COG3485	protocatechuate 3,4-dioxygenase
HUF98_08605	COG0710	3-dehydroquinate dehydratase activity
HUF98_08610	COG3420	alginic acid biosynthetic process
HUF98_08615	COG3659	wide pore channel activity
HUF98_08620	COG4993	Dehydrogenase
HUF98_08630	COG2391	methyltransferase activity
HUF98_08645	COG1414	Transcriptional regulator
HUF98_08650	COG0583	DNA-binding transcription factor activity
HUF98_08655	COG1960	acyl-CoA dehydrogenase activity
HUF98_08680	COG2814	Major facilitator Superfamily
HUF98_08690	COG0154	amidase activity
HUF98_08710	COG4638	Rieske (2fe-2S)
HUF98_08720	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_08730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_08740	COG3733	amine oxidase
HUF98_08750	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_08760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_08765	COG0183	Belongs to the thiolase family
HUF98_08770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_08775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_08785	COG4829	muconolactone delta-isomerase
HUF98_08790	COG4948	Mandelate Racemase Muconate Lactonizing
HUF98_08795	COG0583	DNA-binding transcription factor activity
HUF98_08805	COG2186	Transcriptional regulator
HUF98_08825	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_08840	COG1902	pentaerythritol trinitrate reductase activity
HUF98_08840	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_08855	COG0789	Transcriptional regulator
HUF98_08880	COG1309	transcriptional regulator
HUF98_08885	COG0583	DNA-binding transcription factor activity
HUF98_08890	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_08895	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_08900	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_08910	COG1960	acyl-CoA dehydrogenase activity
HUF98_08920	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_08985	COG2188	Transcriptional regulator
HUF98_09000	COG0583	DNA-binding transcription factor activity
HUF98_09025	COG1566	PFAM secretion protein HlyD family protein
HUF98_09040	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_09045	COG0129	dihydroxy-acid dehydratase activity
HUF98_09055	COG0583	DNA-binding transcription factor activity
HUF98_09060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUF98_09070	COG2084	Dehydrogenase
HUF98_09075	COG2207	Transcriptional regulator
HUF98_09080	COG1064	alcohol dehydrogenase
HUF98_09090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUF98_09095	COG1120	ATPase activity
HUF98_09115	COG0657	acetylesterase activity
HUF98_09130	COG1309	transcriptional regulator
HUF98_09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUF98_09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUF98_09230	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_09245	COG2207	Transcriptional regulator
HUF98_09255	COG2205	protein histidine kinase activity
HUF98_09260	COG0745	RESPONSE REGULATOR receiver
HUF98_09265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_09270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUF98_09350	COG3539	Fimbrial protein
HUF98_09375	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUF98_09385	COG0753	catalase activity
HUF98_09400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUF98_09465	COG1535	isochorismatase
HUF98_09465	COG3433	isochorismatase activity
HUF98_09470	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_09475	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HUF98_09480	COG4149	molybdate abc transporter
HUF98_09485	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUF98_09495	COG4638	Rieske (2fe-2S)
HUF98_09500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HUF98_09505	COG0543	2 iron, 2 sulfur cluster binding
HUF98_09505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_09520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_09530	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_09545	COG2207	Transcriptional regulator
HUF98_09550	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_09555	COG2610	gluconate transmembrane transporter activity
HUF98_09565	COG0583	DNA-binding transcription factor activity
HUF98_09580	COG2031	fatty acid transporter
HUF98_09585	COG0183	Belongs to the thiolase family
HUF98_09590	COG0583	DNA-binding transcription factor activity
HUF98_09595	COG0583	DNA-binding transcription factor activity
HUF98_09610	COG1027	Aspartate ammonia-lyase
HUF98_09620	COG0477	Major facilitator Superfamily
HUF98_09640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_09645	COG4521	taurine ABC transporter
HUF98_09660	COG2188	Transcriptional regulator
HUF98_09670	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUF98_09675	COG1733	regulation of RNA biosynthetic process
HUF98_09680	COG2207	Transcriptional regulator
HUF98_09680	COG3708	Transcriptional regulator
HUF98_09695	COG0730	response to heat
HUF98_09705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_09705	COG3453	Protein conserved in bacteria
HUF98_09715	COG3781	membrane
HUF98_09720	COG1063	alcohol dehydrogenase
HUF98_09730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUF98_09735	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUF98_09740	COG0022	dehydrogenase e1 component
HUF98_09745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUF98_09750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUF98_09765	COG3706	GGDEF domain
HUF98_09780	COG0133	tryptophan synthase activity
HUF98_09790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUF98_09825	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUF98_09850	COG2226	methyltransferase
HUF98_09905	COG0842	Transport permease protein
HUF98_09910	COG0842	Transport permease protein
HUF98_09915	COG1131	(ABC) transporter
HUF98_09930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUF98_09935	COG4773	Receptor
HUF98_09955	COG0730	response to heat
HUF98_09960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUF98_09975	COG0406	alpha-ribazole phosphatase activity
HUF98_09980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUF98_09995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUF98_10025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUF98_10035	COG4264	IucA IucC family
HUF98_10040	COG4264	IucA IucC family
HUF98_10060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUF98_10075	COG1960	acyl-CoA dehydrogenase activity
HUF98_10080	COG1960	acyl-CoA dehydrogenase activity
HUF98_10085	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUF98_10090	COG2207	Transcriptional regulator
HUF98_10095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUF98_10100	COG0776	regulation of translation
HUF98_10125	COG0822	iron-sulfur transferase activity
HUF98_10130	COG0316	Belongs to the HesB IscA family
HUF98_10160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUF98_10180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUF98_10185	COG0702	epimerase
HUF98_10220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUF98_10230	COG0339	signal peptide processing
HUF98_10240	COG4166	transmembrane transport
HUF98_10275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HUF98_10280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HUF98_10310	COG0776	regulation of translation
HUF98_10375	COG0084	hydrolase, TatD family'
HUF98_10395	COG1663	tetraacyldisaccharide 4'-kinase activity
HUF98_10400	COG1132	(ABC) transporter
HUF98_10410	COG0811	peptide transport
HUF98_10415	COG1475	DNA binding
HUF98_10420	COG1192	Involved in chromosome partitioning
HUF98_10430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUF98_10445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUF98_10450	COG0191	fructose-bisphosphate aldolase activity
HUF98_10470	COG0424	maF-like protein
HUF98_10475	COG2850	peptidyl-arginine hydroxylation
HUF98_10485	COG0640	Transcriptional regulator
HUF98_10495	COG3619	membrane
HUF98_10500	COG3122	Protein conserved in bacteria
HUF98_10505	COG1132	(ABC) transporter
HUF98_10525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUF98_10530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUF98_10540	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUF98_10540	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HUF98_10540	COG0506	proline dehydrogenase activity
HUF98_10545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUF98_10560	COG3698	Phosphodiester glycosidase
HUF98_10570	COG2353	YceI-like domain
HUF98_10580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUF98_10625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HUF98_10625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUF98_10650	COG3539	Fimbrial protein
HUF98_10655	COG3121	Chaperone
HUF98_10685	COG0697	spore germination
HUF98_10695	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUF98_10705	COG0583	DNA-binding transcription factor activity
HUF98_10740	COG1522	sequence-specific DNA binding
HUF98_10750	COG1126	abc transporter atp-binding protein
HUF98_10755	COG0765	amino acid transport
HUF98_10760	COG0765	amino acid transport
HUF98_10790	COG1464	Belongs to the NlpA lipoprotein family
HUF98_10800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUF98_10805	COG2011	ABC-type metal ion transport system permease component
HUF98_10810	COG0012	GTP binding
HUF98_10835	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HUF98_10875	COG0386	Belongs to the glutathione peroxidase family
HUF98_10885	COG0436	Aminotransferase
HUF98_10890	COG1301	dicarboxylic acid transport
HUF98_10925	COG3634	alkyl hydroperoxide reductase activity
HUF98_10940	COG0583	DNA-binding transcription factor activity
HUF98_10945	COG0798	PFAM Bile acid sodium symporter
HUF98_10950	COG0640	Transcriptional regulator
HUF98_10965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUF98_10975	COG0583	DNA-binding transcription factor activity
HUF98_10985	COG1953	Uracil, thiamine, allantoin
HUF98_10995	COG2175	clavaminate synthase activity
HUF98_11000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_11005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HUF98_11010	COG4521	taurine ABC transporter
HUF98_11020	COG0477	Major facilitator Superfamily
HUF98_11040	COG1271	oxidase subunit
HUF98_11045	COG1294	oxidase, subunit
HUF98_11055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_11075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUF98_11095	COG3052	prosthetic group binding
HUF98_11100	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HUF98_11110	COG0583	DNA-binding transcription factor activity
HUF98_11120	COG2814	Major facilitator Superfamily
HUF98_11140	COG1346	cytolysis
HUF98_11150	COG0583	DNA-binding transcription factor activity
HUF98_11155	COG0625	glutathione transferase activity
HUF98_11160	COG0625	glutathione transferase activity
HUF98_11165	COG0583	DNA-binding transcription factor activity
HUF98_11180	COG1045	serine acetyltransferase
HUF98_11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUF98_11190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUF98_11195	COG1280	lysine exporter protein (LysE YggA)
HUF98_11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_11210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_11215	COG1126	abc transporter atp-binding protein
HUF98_11220	COG0765	amino acid transport
HUF98_11225	COG0765	amino acid transport
HUF98_11245	COG0784	Response regulator, receiver
HUF98_11245	COG2205	protein histidine kinase activity
HUF98_11265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUF98_11285	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_11335	COG0583	DNA-binding transcription factor activity
HUF98_11355	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_11360	COG1309	transcriptional regulator
HUF98_11365	COG1960	acyl-CoA dehydrogenase activity
HUF98_11370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUF98_11375	COG1024	Enoyl-CoA hydratase
HUF98_11380	COG4770	biotin carboxylase activity
HUF98_11390	COG0583	DNA-binding transcription factor activity
HUF98_11405	COG1960	acyl-CoA dehydrogenase activity
HUF98_11415	COG2814	Major facilitator Superfamily
HUF98_11425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUF98_11430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUF98_11435	COG2814	Major facilitator Superfamily
HUF98_11440	COG1960	acyl-CoA dehydrogenase activity
HUF98_11445	COG1024	Enoyl-CoA hydratase
HUF98_11450	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_11455	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_11460	COG0183	Belongs to the thiolase family
HUF98_11475	COG1280	lysine exporter protein (LysE YggA)
HUF98_11480	COG2192	nodulation
HUF98_11495	COG1024	Enoyl-CoA hydratase
HUF98_11510	COG1960	acyl-CoA dehydrogenase activity
HUF98_11515	COG2814	Major facilitator Superfamily
HUF98_11520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUF98_11525	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUF98_11540	COG3842	ATPase activity
HUF98_11545	COG1840	ABC-type Fe3 transport system, periplasmic component
HUF98_11555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_11570	COG0583	DNA-binding transcription factor activity
HUF98_11575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUF98_11580	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_11590	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUF98_11600	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_11605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_11610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_11615	COG2267	carboxylic ester hydrolase activity
HUF98_11635	COG3038	cytochrome b561
HUF98_11640	COG0753	catalase activity
HUF98_11645	COG2271	Major facilitator Superfamily
HUF98_11650	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUF98_11655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUF98_11670	COG2207	Transcriptional regulator
HUF98_11685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUF98_11715	COG2050	protein possibly involved in aromatic compounds catabolism
HUF98_11725	COG3327	negative regulation of DNA-templated transcription, initiation
HUF98_11735	COG0183	Belongs to the thiolase family
HUF98_11740	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_11745	COG1024	Enoyl-CoA hydratase
HUF98_11750	COG1024	Enoyl-CoA hydratase
HUF98_11755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_11760	COG2151	metal-sulfur cluster biosynthetic enzyme
HUF98_11765	COG3396	Phenylacetate-CoA oxygenase
HUF98_11770	COG3460	Phenylacetate-CoA oxygenase
HUF98_11775	COG3396	Phenylacetate-CoA oxygenase
HUF98_11780	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_11780	COG2030	dehydratase
HUF98_11785	COG1760	l-serine dehydratase
HUF98_11790	COG0531	amino acid
HUF98_11795	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_11820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUF98_11840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_11850	COG0789	Transcriptional regulator
HUF98_11860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUF98_11875	COG2807	transmembrane transport
HUF98_11880	COG0590	tRNA wobble adenosine to inosine editing
HUF98_12045	COG1116	anion transmembrane transporter activity
HUF98_12050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUF98_12060	COG0864	Transcriptional regulator
HUF98_12070	COG1733	regulation of RNA biosynthetic process
HUF98_12075	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUF98_12080	COG0439	Biotin carboxylase
HUF98_12095	COG1063	alcohol dehydrogenase
HUF98_12105	COG1309	transcriptional regulator
HUF98_12115	COG0038	chloride channel
HUF98_12120	COG4770	biotin carboxylase activity
HUF98_12140	COG1914	H( )-stimulated, divalent metal cation uptake system
HUF98_12145	COG0583	DNA-binding transcription factor activity
HUF98_12175	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUF98_12200	COG3293	Transposase
HUF98_12215	COG1560	Kdo2-lipid A biosynthetic process
HUF98_12225	COG5006	permease, DMT superfamily
HUF98_12230	COG1522	sequence-specific DNA binding
HUF98_12245	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HUF98_12255	COG4122	O-methyltransferase activity
HUF98_12285	COG1538	Outer membrane efflux protein
HUF98_12290	COG1137	ATPase activity
HUF98_12295	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HUF98_12305	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HUF98_12310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUF98_12310	COG0517	IMP dehydrogenase activity
HUF98_12345	COG2814	Major facilitator Superfamily
HUF98_12380	COG1278	Cold shock
HUF98_12385	COG1280	lysine exporter protein (LysE YggA)
HUF98_12415	COG1570	exodeoxyribonuclease VII activity
HUF98_12465	COG0583	DNA-binding transcription factor activity
HUF98_12470	COG4638	Rieske (2fe-2S)
HUF98_12475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HUF98_12480	COG0633	Ferredoxin
HUF98_12480	COG0543	2 iron, 2 sulfur cluster binding
HUF98_12485	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_12490	COG3135	benzoate transporter
HUF98_12495	COG2814	Major facilitator Superfamily
HUF98_12510	COG1643	Atp-dependent helicase
HUF98_12515	COG0450	alkyl hydroperoxide reductase
HUF98_12525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUF98_12535	COG3634	alkyl hydroperoxide reductase activity
HUF98_12555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUF98_12560	COG0625	glutathione transferase activity
HUF98_12570	COG2885	chlorophyll binding
HUF98_12605	COG0542	response to heat
HUF98_12620	COG1765	OsmC-like protein
HUF98_12640	COG0667	Aldo Keto reductase
HUF98_12655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUF98_12665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUF98_12675	COG0527	aspartate kinase activity
HUF98_12685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUF98_12695	COG3038	cytochrome b561
HUF98_12700	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUF98_12705	COG2252	PERMEase
HUF98_12715	COG2072	flavoprotein involved in K transport
HUF98_12730	COG1741	Belongs to the pirin family
HUF98_12735	COG1309	transcriptional regulator
HUF98_12745	COG0300	oxidoreductase activity
HUF98_12750	COG2072	flavoprotein involved in K transport
HUF98_12755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUF98_12800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUF98_12815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUF98_12835	COG1024	Enoyl-CoA hydratase
HUF98_12840	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_12850	COG1960	acyl-CoA dehydrogenase activity
HUF98_12875	COG0697	spore germination
HUF98_12920	COG1113	amino acid transport
HUF98_12940	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_12960	COG0531	amino acid
HUF98_12970	COG1113	amino acid transport
HUF98_13010	COG4269	membrane
HUF98_13025	COG1309	transcriptional regulator
HUF98_13030	COG3328	transposase activity
HUF98_13055	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HUF98_13085	COG3152	Membrane
HUF98_13135	COG0582	viral genome integration into host DNA
HUF98_13145	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUF98_13145	COG1902	pentaerythritol trinitrate reductase activity
HUF98_13155	COG2203	Gaf domain
HUF98_13155	COG3706	GGDEF domain
HUF98_13155	COG5001	Diguanylate cyclase
HUF98_13155	COG4251	negative regulation of phosphorylation
HUF98_13165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_13195	COG4172	Belongs to the ABC transporter superfamily
HUF98_13200	COG4239	(ABC) transporter, permease
HUF98_13205	COG4174	ABC transporter (Permease)
HUF98_13215	COG1388	LysM domain
HUF98_13215	COG0741	lytic transglycosylase activity
HUF98_13215	COG1388	LysM domain
HUF98_13215	COG0741	lytic transglycosylase activity
HUF98_13220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUF98_13260	COG0583	DNA-binding transcription factor activity
HUF98_13265	COG1279	arginine transmembrane transporter activity
HUF98_13285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_13290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUF98_13295	COG0006	proline dipeptidase activity
HUF98_13325	COG2194	sulfuric ester hydrolase activity
HUF98_13610	COG3620	sequence-specific DNA binding
HUF98_13675	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUF98_13695	COG3384	dioxygenase
HUF98_13705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUF98_13710	COG2878	Part of a membrane complex involved in electron transport
HUF98_13715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUF98_13740	COG0768	penicillin binding
HUF98_13745	COG0742	ribosomal rna small subunit methyltransferase
HUF98_13760	COG0830	nickel cation binding
HUF98_13770	COG0804	urea catabolic process
HUF98_13815	COG1253	flavin adenine dinucleotide binding
HUF98_13820	COG2851	Citrate transporter
HUF98_13870	COG1773	rubredoxin
HUF98_13875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUF98_13885	COG0583	DNA-binding transcription factor activity
HUF98_13915	COG4181	ATPase activity
HUF98_13940	COG4771	TonB-dependent receptor
HUF98_13960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUF98_13980	COG0306	phosphate transporter
HUF98_14005	COG2223	nitrite transmembrane transporter activity
HUF98_14010	COG2207	Transcriptional regulator
HUF98_14015	COG2066	Belongs to the glutaminase family
HUF98_14025	COG0477	Major facilitator Superfamily
HUF98_14035	COG0028	Belongs to the TPP enzyme family
HUF98_14050	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_14055	COG2267	carboxylic ester hydrolase activity
HUF98_14065	COG2271	Major facilitator Superfamily
HUF98_14100	COG1414	Transcriptional regulator
HUF98_14115	COG1024	Enoyl-CoA hydratase
HUF98_14125	COG1215	transferase activity, transferring glycosyl groups
HUF98_14130	COG0726	polysaccharide deacetylase
HUF98_14130	COG1649	PFAM Uncharacterised BCR, COG1649
HUF98_14140	COG4681	YaeQ
HUF98_14150	COG0523	cobalamin synthesis protein
HUF98_14160	COG1607	acyl-coa hydrolase
HUF98_14170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_14175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUF98_14180	COG1309	transcriptional regulator
HUF98_14205	COG2040	homocysteine
HUF98_14210	COG0531	amino acid
HUF98_14235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_14240	COG0477	Major facilitator Superfamily
HUF98_14280	COG0405	Gamma-glutamyltransferase
HUF98_14285	COG2814	Major facilitator Superfamily
HUF98_14295	COG2050	protein possibly involved in aromatic compounds catabolism
HUF98_14310	COG1090	epimerase
HUF98_14330	COG0420	3'-5' exonuclease activity
HUF98_14355	COG0735	belongs to the Fur family
HUF98_14360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUF98_14380	COG0121	glutamine amidotransferase
HUF98_14395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUF98_14405	COG0210	DNA helicase
HUF98_14410	COG2885	chlorophyll binding
HUF98_14415	COG0204	Acyl-transferase
HUF98_14430	COG2894	cell division
HUF98_14445	COG1280	lysine exporter protein (LysE YggA)
HUF98_14450	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUF98_14450	COG1674	ftsk spoiiie
HUF98_14455	COG0492	ferredoxin-NADP+ reductase activity
HUF98_14460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HUF98_14470	COG0456	acetyltransferase
HUF98_14515	COG1981	membrane
HUF98_14530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUF98_14530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUF98_14550	COG1012	belongs to the aldehyde dehydrogenase family
HUF98_14560	COG0657	acetylesterase activity
HUF98_14570	COG0473	3-isopropylmalate dehydrogenase activity
HUF98_14575	COG0583	DNA-binding transcription factor activity
HUF98_14595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_14630	COG0358	DNA primase activity
HUF98_14645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HUF98_14675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUF98_14705	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUF98_14715	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUF98_14715	COG0351	phosphomethylpyrimidine kinase
HUF98_14715	COG0352	thiamine-phosphate diphosphorylase activity
HUF98_14720	COG1652	LysM domain
HUF98_14745	COG1399	metal-binding, possibly nucleic acid-binding protein
HUF98_14750	COG3101	peptidyl-lysine hydroxylation
HUF98_14755	COG0009	L-threonylcarbamoyladenylate synthase
HUF98_14760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUF98_14765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUF98_14780	COG4106	trans-aconitate 2-methyltransferase activity
HUF98_14795	COG0596	Alpha beta hydrolase
HUF98_14795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_14795	COG2226	methyltransferase
HUF98_14800	COG1877	trehalose-phosphatase activity
HUF98_14805	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUF98_14810	COG2223	nitrite transmembrane transporter activity
HUF98_14830	COG1196	nuclear chromosome segregation
HUF98_14840	COG0730	response to heat
HUF98_14855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUF98_14865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUF98_14915	COG0489	protein tyrosine kinase activity
HUF98_14925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_14925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_14955	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUF98_14960	COG2081	HI0933 family
HUF98_14970	COG0668	transmembrane transport
HUF98_14990	COG0583	DNA-binding transcription factor activity
HUF98_15010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUF98_15015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUF98_15045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUF98_15085	COG0745	RESPONSE REGULATOR receiver
HUF98_15105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUF98_15115	COG0384	phenazine biosynthesis protein PhzF
HUF98_15150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUF98_15165	COG0583	DNA-binding transcription factor activity
HUF98_15195	COG0583	DNA-binding transcription factor activity
HUF98_15210	COG0583	DNA-binding transcription factor activity
HUF98_15215	COG1053	succinate dehydrogenase
HUF98_15225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUF98_15230	COG2814	Major facilitator Superfamily
HUF98_15235	COG1960	acyl-CoA dehydrogenase activity
HUF98_15240	COG0583	DNA-binding transcription factor activity
HUF98_15245	COG1063	alcohol dehydrogenase
HUF98_15275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUF98_15280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUF98_15285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUF98_15300	COG3667	copper resistance
HUF98_15305	COG2132	Multicopper oxidase
HUF98_15315	COG0561	phosphatase activity
HUF98_15320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUF98_15330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUF98_15345	COG1214	PFAM Peptidase M22, glycoprotease
HUF98_15395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUF98_15405	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUF98_15410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUF98_15415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUF98_15475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUF98_15485	COG1846	Transcriptional regulator
HUF98_15490	COG1764	response to oxidative stress
HUF98_15530	COG0037	tRNA processing
HUF98_15540	COG0248	Ppx GppA phosphatase
HUF98_15570	COG0072	phenylalanine-tRNA ligase activity
HUF98_15610	COG1238	metal cluster binding
HUF98_15615	COG0625	glutathione transferase activity
HUF98_15630	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_15635	COG3028	Belongs to the UPF0307 family
HUF98_15640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUF98_15660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUF98_15665	COG0617	tRNA 3'-terminal CCA addition
HUF98_15670	COG1555	photosystem II stabilization
HUF98_15675	COG3956	TIGRFAM MazG family protein
HUF98_15685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUF98_15705	COG0784	Response regulator, receiver
HUF98_15705	COG2205	protein histidine kinase activity
HUF98_15705	COG5002	protein histidine kinase activity
HUF98_15710	COG1024	Enoyl-CoA hydratase
HUF98_15715	COG2084	Dehydrogenase
HUF98_15720	COG3622	Belongs to the hyi family
HUF98_15755	COG0697	spore germination
HUF98_15765	COG2814	Major facilitator Superfamily
HUF98_15785	COG2132	Multicopper oxidase
HUF98_15800	COG2205	protein histidine kinase activity
HUF98_15830	COG0488	(ABC) transporter
HUF98_15920	COG2826	transposase and inactivated derivatives, IS30 family
HUF98_15930	COG2826	transposase and inactivated derivatives, IS30 family
HUF98_16000	COG1132	(ABC) transporter
HUF98_16050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUF98_16080	COG3293	Transposase
HUF98_16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_16135	COG1683	Conserved Protein
HUF98_16170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_16180	COG1683	Conserved Protein
HUF98_16215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_16225	COG1683	Conserved Protein
HUF98_16270	COG0583	DNA-binding transcription factor activity
HUF98_16440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUF98_16450	COG0583	DNA-binding transcription factor activity
HUF98_16460	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUF98_16470	COG0084	hydrolase, TatD family'
HUF98_16485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HUF98_16515	COG0440	acetolactate synthase activity
HUF98_16520	COG0028	Belongs to the TPP enzyme family
HUF98_16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUF98_16550	COG1136	(ABC) transporter
HUF98_16550	COG0577	efflux transmembrane transporter activity
HUF98_16555	COG1538	Outer membrane efflux protein
HUF98_16570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUF98_16575	COG1162	GTPase activity
HUF98_16585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUF98_16605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUF98_16610	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_16650	COG2986	histidine ammonia-lyase
HUF98_16660	COG1216	Glycosyl transferase, family 2
HUF98_16665	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_16675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUF98_16720	COG1426	Protein conserved in bacteria
HUF98_16755	COG0793	Belongs to the peptidase S41A family
HUF98_16770	COG2267	carboxylic ester hydrolase activity
HUF98_16785	COG3265	gluconokinase activity
HUF98_16795	COG0800	Aldolase
HUF98_16805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUF98_16810	COG0280	phosphate acetyltransferase
HUF98_16810	COG0857	belongs to the CobB CobQ family
HUF98_16815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUF98_16815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUF98_16835	COG0740	serine-type endopeptidase activity
HUF98_16845	COG4774	siderophore transport
HUF98_16855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUF98_16865	COG2813	Specifically methylates the guanine in position
HUF98_16865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUF98_16965	COG0788	formyltetrahydrofolate deformylase activity
HUF98_16990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUF98_16990	COG4651	solute:proton antiporter activity
HUF98_17010	COG0724	RNA recognition motif
HUF98_17015	COG0210	DNA helicase
HUF98_17040	COG1733	regulation of RNA biosynthetic process
HUF98_17050	COG2900	Belongs to the SlyX family
HUF98_17055	COG0488	(ABC) transporter
HUF98_17060	COG1280	lysine exporter protein (LysE YggA)
HUF98_17065	COG1560	Kdo2-lipid A biosynthetic process
HUF98_17075	COG1301	dicarboxylic acid transport
HUF98_17130	COG0473	3-isopropylmalate dehydrogenase activity
HUF98_17185	COG0583	DNA-binding transcription factor activity
HUF98_17195	COG0625	glutathione transferase activity
HUF98_17200	COG2378	regulation of single-species biofilm formation
HUF98_17205	COG0546	phosphoglycolate phosphatase activity
HUF98_17215	COG1530	ribonuclease E activity
HUF98_17220	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_17235	COG0583	DNA-binding transcription factor activity
HUF98_17240	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_17245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUF98_17255	COG0534	Mate efflux family protein
HUF98_17270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUF98_17300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HUF98_17300	COG0493	'glutamate synthase
HUF98_17310	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HUF98_17315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUF98_17330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUF98_17340	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HUF98_17340	COG0644	oxidoreductase
HUF98_17350	COG0425	Belongs to the sulfur carrier protein TusA family
HUF98_17355	COG4535	Mg2 and Co2 transporter CorC
HUF98_17365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUF98_17385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUF98_17390	COG0475	glutathione-regulated potassium exporter activity
HUF98_17390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUF98_17405	COG0484	heat shock protein binding
HUF98_17410	COG0789	Transcriptional regulator
HUF98_17415	COG0598	Magnesium transport protein CorA
HUF98_17430	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUF98_17435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUF98_17440	COG1074	ATP-dependent DNA helicase activity
HUF98_17445	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HUF98_17465	COG2226	methyltransferase
HUF98_17485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUF98_17500	COG2111	Na H antiporter
HUF98_17500	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUF98_17505	COG1006	Multisubunit Na H antiporter MnhC subunit
HUF98_17510	COG0651	ATP synthesis coupled electron transport
HUF98_17515	COG1863	multisubunit Na H antiporter MnhE subunit
HUF98_17520	COG2212	antiporter activity
HUF98_17525	COG1320	monovalent cation:proton antiporter activity
HUF98_17540	COG0195	Participates in both transcription termination and antitermination
HUF98_17590	COG0237	dephospho-CoA kinase activity
HUF98_17600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUF98_17615	COG0497	DNA recombination
HUF98_17625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HUF98_17655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUF98_17655	COG2169	Transcriptional regulator
HUF98_17660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUF98_17725	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUF98_17740	COG0326	Molecular chaperone. Has ATPase activity
HUF98_17755	COG2056	Na+-H+ antiporter family
HUF98_17760	COG0596	Alpha beta hydrolase
HUF98_17855	COG0546	phosphoglycolate phosphatase activity
HUF98_17860	COG1716	ATPase activity
HUF98_17905	COG0181	hydroxymethylbilane synthase activity
HUF98_17915	COG3275	phosphorelay sensor kinase activity
HUF98_17935	COG1538	Outer membrane efflux protein
HUF98_17940	COG0697	spore germination
HUF98_17965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUF98_17970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUF98_17975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUF98_17980	COG0772	Belongs to the SEDS family
HUF98_18005	COG4974	Belongs to the 'phage' integrase family
HUF98_18010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_18020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUF98_18030	COG2197	response regulator
HUF98_18045	COG0793	Belongs to the peptidase S41A family
HUF98_18050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HUF98_18055	COG0795	lipopolysaccharide-transporting ATPase activity
HUF98_18095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUF98_18095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUF98_18105	COG0004	ammonium transporteR
HUF98_18110	COG0347	Belongs to the P(II) protein family
HUF98_18120	COG0606	chelatase, subunit chli
HUF98_18125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUF98_18135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUF98_18155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUF98_18170	COG0318	PFAM AMP-dependent synthetase and ligase
HUF98_18180	COG0477	Major facilitator Superfamily
HUF98_18185	COG2860	membrane
HUF98_18195	COG1253	flavin adenine dinucleotide binding
HUF98_18205	COG0477	Major facilitator Superfamily
HUF98_18215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUF98_18250	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUF98_18260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUF98_18295	COG1309	transcriptional regulator
HUF98_18330	COG0758	DNA mediated transformation
HUF98_18340	COG0697	spore germination
HUF98_18345	COG1309	transcriptional regulator
HUF98_18360	COG0386	Belongs to the glutathione peroxidase family
HUF98_18425	COG1121	(ABC) transporter
HUF98_18430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUF98_18435	COG1280	lysine exporter protein (LysE YggA)
HUF98_18440	COG2837	iron assimilation
HUF98_18445	COG0281	malic enzyme
HUF98_18490	COG0519	Catalyzes the synthesis of GMP from XMP
HUF98_18490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUF98_18495	COG4399	Belongs to the UPF0754 family
HUF98_18500	COG2259	Doxx family
HUF98_18505	COG0586	Pfam SNARE associated Golgi protein
HUF98_18520	COG1192	Involved in chromosome partitioning
HUF98_18530	COG0271	Belongs to the BolA IbaG family
HUF98_18550	COG2267	carboxylic ester hydrolase activity
HUF98_18570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUF98_18570	COG3321	synthase
HUF98_18570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUF98_18570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUF98_18575	COG1960	acyl-CoA dehydrogenase activity
HUF98_18595	COG3916	Acyl-homoserine-lactone synthase
HUF98_18600	COG0477	Major facilitator Superfamily
HUF98_18605	COG1024	Enoyl-CoA hydratase
HUF98_18610	COG1024	Enoyl-CoA hydratase
HUF98_18615	COG1960	acyl-CoA dehydrogenase activity
HUF98_18620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUF98_18640	COG1113	amino acid transport
HUF98_18645	COG1113	amino acid transport
HUF98_18650	COG0251	oxidation-reduction process
HUF98_18690	COG0564	pseudouridine synthase activity
HUF98_18770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUF98_18785	COG1802	Transcriptional regulator
HUF98_18795	COG1448	Aminotransferase
HUF98_18800	COG0277	FAD linked oxidase domain protein
HUF98_18810	COG2186	Transcriptional regulator
HUF98_18820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUF98_18825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUF98_18840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUF98_18845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUF98_18850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUF98_18900	COG2244	polysaccharide biosynthetic process
HUF98_18905	COG1083	cytidylyl-transferase
HUF98_18910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUF98_18920	COG2089	acid synthase
HUF98_18925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUF98_18930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUF98_18940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HUF98_18945	COG1596	polysaccharide export
HUF98_18970	COG0728	peptidoglycan biosynthetic process
HUF98_18975	COG3023	N-Acetylmuramoyl-L-alanine amidase
HUF98_19030	COG0546	phosphoglycolate phosphatase activity
HUF98_19035	COG1028	Short-chain dehydrogenase reductase Sdr
HUF98_19055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_19060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUF98_19065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUF98_19070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUF98_19075	COG1116	anion transmembrane transporter activity
HUF98_19080	COG1309	transcriptional regulator
HUF98_19085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUF98_19095	COG0196	riboflavin kinase activity
HUF98_19100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUF98_19110	COG1047	Peptidyl-prolyl cis-trans
HUF98_19150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUF98_19155	COG0657	acetylesterase activity
HUF98_19205	COG2951	lytic endotransglycosylase activity
HUF98_19210	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUF98_19225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUF98_19235	COG0671	phosphoesterase, PA-phosphatase related
HUF98_19240	COG0861	Integral membrane protein TerC family
HUF98_19250	COG0754	glutathionylspermidine amidase activity
HUF98_19260	COG0402	S-adenosylhomocysteine deaminase activity
HUF98_19275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUF98_19295	COG0706	membrane insertase activity
HUF98_19345	COG4683	PFAM Phage derived protein Gp49-like (DUF891)