locus-tag	class	description
N7285_00075	COG0784	Response regulator, receiver
N7285_00075	COG2198	Histidine kinase
N7285_00075	COG2205	protein histidine kinase activity
N7285_00080	COG3162	membrane
N7285_00085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7285_00095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7285_00115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7285_00120	COG1309	transcriptional regulator
N7285_00140	COG0351	phosphomethylpyrimidine kinase
N7285_00140	COG0352	thiamine-phosphate diphosphorylase activity
N7285_00140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7285_00150	COG2814	Major facilitator Superfamily
N7285_00165	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N7285_00175	COG1113	amino acid transport
N7285_00185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7285_00190	COG1012	belongs to the aldehyde dehydrogenase family
N7285_00200	COG1335	isochorismatase
N7285_00230	COG2814	Major facilitator Superfamily
N7285_00235	COG0583	DNA-binding transcription factor activity
N7285_00255	COG0667	Aldo Keto reductase
N7285_00290	COG1733	regulation of RNA biosynthetic process
N7285_00295	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7285_00360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7285_00375	COG2329	Antibiotic biosynthesis monooxygenase
N7285_00405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7285_00435	COG0427	acetyl-CoA hydrolase
N7285_00460	COG0659	secondary active sulfate transmembrane transporter activity
N7285_00465	COG4221	oxidoreductase activity
N7285_00470	COG2873	o-acetylhomoserine
N7285_00475	COG0488	(ABC) transporter
N7285_00560	COG0833	amino acid
N7285_00605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7285_00610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N7285_00625	COG2226	methyltransferase
N7285_00675	COG0070	glutamate synthase
N7285_00675	COG0069	glutamate synthase activity
N7285_00675	COG0067	glutamate synthase
N7285_00680	COG0493	'glutamate synthase
N7285_00690	COG1704	LemA family
N7285_00695	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N7285_00715	COG3307	-O-antigen
N7285_00735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7285_00750	COG0194	GDP metabolic process
N7285_00800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7285_00820	COG5380	lipid catabolic process
N7285_00825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7285_00850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7285_00855	COG0277	FAD linked oxidase domain protein
N7285_00865	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7285_00870	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7285_00885	COG1289	transmembrane transporter activity
N7285_00895	COG0628	permease
N7285_00900	COG1192	Involved in chromosome partitioning
N7285_00930	COG0833	amino acid
N7285_00935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7285_00940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7285_00950	COG1012	belongs to the aldehyde dehydrogenase family
N7285_00990	COG0583	DNA-binding transcription factor activity
N7285_01035	COG0517	IMP dehydrogenase activity
N7285_01040	COG1983	PspC domain protein
N7285_01050	COG1960	acyl-CoA dehydrogenase activity
N7285_01065	COG0408	coproporphyrinogen oxidase activity
N7285_01085	COG0513	Belongs to the DEAD box helicase family
N7285_01095	COG1127	ABC transporter
N7285_01100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N7285_01110	COG2854	intermembrane phospholipid transfer
N7285_01120	COG0598	Magnesium transport protein CorA
N7285_01130	COG0494	nUDIX hydrolase
N7285_01135	COG1040	competence protein
N7285_01140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7285_01160	COG1946	Acyl-CoA thioesterase
N7285_01165	COG1301	dicarboxylic acid transport
N7285_01180	COG1959	2 iron, 2 sulfur cluster binding
N7285_01185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7285_01185	COG1017	nitric oxide dioxygenase activity
N7285_01190	COG0433	COG0433 Predicted ATPase
N7285_01195	COG0626	cystathionine gamma-synthase activity
N7285_01350	COG1960	acyl-CoA dehydrogenase activity
N7285_01355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N7285_01385	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N7285_01390	COG0339	signal peptide processing
N7285_01395	COG0557	exoribonuclease II activity
N7285_01440	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7285_01445	COG2169	Transcriptional regulator
N7285_01450	COG0697	spore germination
N7285_01455	COG1295	ribonuclease BN
N7285_01490	COG1702	phosphate starvation-inducible protein PhoH
N7285_01500	COG0739	heme binding
N7285_01500	COG1196	nuclear chromosome segregation
N7285_01500	COG0741	lytic transglycosylase activity
N7285_01530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N7285_01535	COG1183	phosphatidylcholine synthase activity
N7285_01580	COG1960	acyl-CoA dehydrogenase activity
N7285_01585	COG1309	transcriptional regulator
N7285_01600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7285_01605	COG1960	acyl-CoA dehydrogenase activity
N7285_01625	COG2969	positive regulation of protein catabolic process
N7285_01635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7285_01650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7285_01655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7285_01675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7285_01685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7285_01690	COG1408	metallophosphoesterase
N7285_01700	COG2199	diguanylate cyclase activity
N7285_01760	COG1607	acyl-coa hydrolase
N7285_01790	COG2350	Protein conserved in bacteria
N7285_01800	COG0613	PHP domain protein
N7285_01805	COG3781	membrane
N7285_01815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7285_01820	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7285_01830	COG1862	Preprotein translocase
N7285_01860	COG2205	protein histidine kinase activity
N7285_01865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N7285_01885	COG0726	polysaccharide deacetylase
N7285_01890	COG0463	Glycosyl transferase, family 2
N7285_01895	COG0438	transferase activity, transferring glycosyl groups
N7285_01960	COG0625	glutathione transferase activity
N7285_01965	COG0583	DNA-binding transcription factor activity
N7285_01970	COG1960	acyl-CoA dehydrogenase activity
N7285_01975	COG1960	acyl-CoA dehydrogenase activity
N7285_01985	COG2205	protein histidine kinase activity
N7285_01990	COG0745	RESPONSE REGULATOR receiver
N7285_01995	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N7285_02015	COG2096	Adenosyltransferase
N7285_02065	COG0285	dihydrofolate synthase activity
N7285_02085	COG0450	alkyl hydroperoxide reductase
N7285_02100	COG0477	Major facilitator Superfamily
N7285_02105	COG1272	protein, Hemolysin III
N7285_02135	COG0183	Belongs to the thiolase family
N7285_02140	COG2207	Transcriptional regulator
N7285_02160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7285_02180	COG0183	Belongs to the thiolase family
N7285_02190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N7285_02190	COG2885	chlorophyll binding
N7285_02200	COG1690	Belongs to the RtcB family
N7285_02205	COG0833	amino acid
N7285_02215	COG2233	PERMEase
N7285_02220	COG1217	gtp-binding protein TYPA
N7285_02245	COG2094	Belongs to the DNA glycosylase MPG family
N7285_02265	COG1902	pentaerythritol trinitrate reductase activity
N7285_02280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7285_02285	COG0354	folic acid binding
N7285_02295	COG3189	MarR family transcriptional regulator
N7285_02300	COG2824	Alkylphosphonate utilization operon protein PhnA
N7285_02305	COG3422	double-strand break repair
N7285_02345	COG0840	transmembrane signaling receptor activity
N7285_02365	COG5510	response to toxic substance
N7285_02375	COG2832	Protein of unknown function (DUF454)
N7285_02380	COG1376	ErfK ybiS ycfS ynhG family protein
N7285_02420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7285_02430	COG1289	transmembrane transporter activity
N7285_02435	COG2814	Major facilitator Superfamily
N7285_02455	COG1115	amino acid carrier protein
N7285_02460	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7285_02465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7285_02470	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N7285_02510	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7285_02520	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7285_02525	COG1077	Cell shape determining protein MreB Mrl
N7285_02530	COG1792	Involved in formation and maintenance of cell shape
N7285_02535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N7285_02540	COG0424	maF-like protein
N7285_02545	COG1530	ribonuclease E activity
N7285_02555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7285_02565	COG0560	Phosphoserine phosphatase
N7285_02575	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7285_02600	COG2207	Transcriptional regulator
N7285_02620	COG1113	amino acid transport
N7285_02625	COG2828	Protein conserved in bacteria
N7285_02630	COG0142	geranyltranstransferase activity
N7285_02635	COG2315	Protein conserved in bacteria
N7285_02650	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7285_02670	COG2194	sulfuric ester hydrolase activity
N7285_02675	COG0745	RESPONSE REGULATOR receiver
N7285_02680	COG0642	Histidine kinase
N7285_02690	COG0004	ammonium transporteR
N7285_02695	COG0583	DNA-binding transcription factor activity
N7285_02715	COG0525	valine-tRNA ligase activity
N7285_02725	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_02735	COG0393	Putative heavy-metal-binding
N7285_02740	COG0393	Putative heavy-metal-binding
N7285_02745	COG1538	Outer membrane efflux protein
N7285_02755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_02760	COG0671	phosphoesterase, PA-phosphatase related
N7285_02790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7285_02805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7285_02805	COG1648	precorrin-2 dehydrogenase activity
N7285_02810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7285_02815	COG1733	regulation of RNA biosynthetic process
N7285_02825	COG0531	amino acid
N7285_02840	COG0321	lipoyl(octanoyl) transferase activity
N7285_02845	COG2921	Belongs to the UPF0250 family
N7285_02885	COG2009	succinate dehydrogenase
N7285_02890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N7285_02895	COG1053	succinate dehydrogenase
N7285_02900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N7285_02925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7285_02945	COG2354	Protein conserved in bacteria
N7285_02950	COG2321	neutral zinc metallopeptidase
N7285_02970	COG2843	Capsule synthesis protein
N7285_02985	COG0589	response to stress
N7285_03005	COG0505	Belongs to the CarA family
N7285_03030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7285_03035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7285_03085	COG0477	Major facilitator Superfamily
N7285_03090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7285_03105	COG1597	lipid kinase activity
N7285_03110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N7285_03140	COG0584	glycerophosphoryl diester phosphodiesterase
N7285_03160	COG0741	lytic transglycosylase activity
N7285_03180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7285_03195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7285_03225	COG0778	Nitroreductase
N7285_03240	COG1929	Belongs to the glycerate kinase type-1 family
N7285_03245	COG0243	molybdopterin cofactor binding
N7285_03250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7285_03255	COG3339	Conserved Protein
N7285_03265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N7285_03280	COG1113	amino acid transport
N7285_03290	COG0019	diaminopimelate decarboxylase activity
N7285_03300	COG1280	lysine exporter protein (LysE YggA)
N7285_03305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N7285_03335	COG0463	Glycosyl transferase, family 2
N7285_03355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_03390	COG4591	ABC-type transport system involved in lipoprotein release permease component
N7285_03395	COG1136	(ABC) transporter
N7285_03400	COG2333	competence protein COMEC
N7285_03400	COG0658	competence protein
N7285_03410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N7285_03410	COG0616	signal peptide processing
N7285_03415	COG0596	Alpha beta hydrolase
N7285_03420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7285_03430	COG0628	permease
N7285_03465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7285_03485	COG0823	Involved in the tonB-independent uptake of proteins
N7285_03505	COG0824	Thioesterase
N7285_03510	COG1473	amidohydrolase
N7285_03530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7285_03530	COG0047	phosphoribosylformylglycinamidine synthase activity
N7285_03535	COG2814	Major facilitator Superfamily
N7285_03550	COG1024	Enoyl-CoA hydratase
N7285_03555	COG1051	belongs to the nudix hydrolase family
N7285_03555	COG1056	cytidyltransferase-related domain
N7285_03565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7285_03580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N7285_03595	COG4625	pathogenesis
N7285_03600	COG0583	DNA-binding transcription factor activity
N7285_03605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7285_03610	COG4208	sulfate ABC transporter
N7285_03615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N7285_03625	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N7285_03630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7285_03635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7285_03655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7285_03670	COG0681	Belongs to the peptidase S26 family
N7285_03685	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7285_03695	COG1381	Involved in DNA repair and RecF pathway recombination
N7285_03700	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N7285_03710	COG4221	oxidoreductase activity
N7285_03740	COG0436	Aminotransferase
N7285_03760	COG0556	nucleotide-excision repair
N7285_03815	COG2070	2-Nitropropane dioxygenase
N7285_03845	COG1215	transferase activity, transferring glycosyl groups
N7285_03860	COG0415	Belongs to the DNA photolyase family
N7285_03870	COG1252	NADH dehydrogenase
N7285_03875	COG1686	Belongs to the peptidase S11 family
N7285_03890	COG1187	pseudouridine synthase activity
N7285_03915	COG0477	Major facilitator Superfamily
N7285_03920	COG0583	DNA-binding transcription factor activity
N7285_03925	COG1823	symporter activity
N7285_03935	COG0612	Peptidase, M16
N7285_03960	COG0352	thiamine-phosphate diphosphorylase activity
N7285_03995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7285_04010	COG1309	transcriptional regulator
N7285_04020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7285_04025	COG0076	glutamate decarboxylase activity
N7285_04035	COG1522	sequence-specific DNA binding
N7285_04040	COG3961	Belongs to the TPP enzyme family
N7285_04045	COG1113	amino acid transport
N7285_04050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N7285_04055	COG0573	inorganic phosphate transmembrane transporter activity
N7285_04065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7285_04070	COG0616	signal peptide processing
N7285_04080	COG3328	transposase activity
N7285_04110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7285_04115	COG1686	Belongs to the peptidase S11 family
N7285_04140	COG0583	DNA-binding transcription factor activity
N7285_04145	COG1067	ATP-dependent peptidase activity
N7285_04190	COG1966	Carbon starvation protein
N7285_04195	COG2879	small protein
N7285_04230	COG2508	Transcriptional regulator
N7285_04230	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7285_04250	COG1113	amino acid transport
N7285_04255	COG0583	DNA-binding transcription factor activity
N7285_04260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7285_04265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7285_04275	COG1012	belongs to the aldehyde dehydrogenase family
N7285_04285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7285_04290	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
N7285_04290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7285_04325	COG2814	Major facilitator Superfamily
N7285_04330	COG4948	Mandelate Racemase Muconate Lactonizing
N7285_04340	COG1309	transcriptional regulator
N7285_04360	COG1741	Belongs to the pirin family
N7285_04370	COG2964	Protein conserved in bacteria
N7285_04385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7285_04395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7285_04400	COG4605	iron ion homeostasis
N7285_04405	COG4604	ABC transporter, ATP-binding protein
N7285_04410	COG4607	ABC-type enterochelin transport system periplasmic component
N7285_04415	COG4774	siderophore transport
N7285_04425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7285_04430	COG1021	2,3-dihydroxybenzoate-AMP ligase
N7285_04435	COG1535	isochorismatase
N7285_04435	COG3433	isochorismatase activity
N7285_04450	COG1132	(ABC) transporter
N7285_04455	COG1132	(ABC) transporter
N7285_04460	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N7285_04470	COG1169	isochorismate synthase
N7285_04485	COG3739	integral membrane protein
N7285_04510	COG0302	gtp cyclohydrolase
N7285_04520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N7285_04550	COG0308	aminopeptidase N
N7285_04555	COG0512	Glutamine amidotransferase of anthranilate synthase
N7285_04735	COG5410	chromosome segregation
N7285_04740	COG3567	Phage-associated protein, HI1409 family
N7285_04760	COG3566	protein conserved in bacteria
N7285_04870	COG0582	viral genome integration into host DNA
N7285_04885	COG0174	glutamine synthetase
N7285_04895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N7285_04930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7285_04935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N7285_04940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7285_04960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N7285_04965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N7285_04970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N7285_04985	COG1960	acyl-CoA dehydrogenase activity
N7285_04990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7285_04995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7285_05005	COG2223	nitrite transmembrane transporter activity
N7285_05015	COG0024	Methionine aminopeptidase
N7285_05020	COG0052	Belongs to the universal ribosomal protein uS2 family
N7285_05035	COG2207	Transcriptional regulator
N7285_05060	COG2951	lytic endotransglycosylase activity
N7285_05065	COG0772	Belongs to the SEDS family
N7285_05080	COG0842	Transport permease protein
N7285_05085	COG1131	(ABC) transporter
N7285_05130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_05145	COG4215	(ABC) transporter
N7285_05150	COG4160	amino acid transport
N7285_05155	COG4598	ABC transporter
N7285_05165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N7285_05170	COG0826	peptidase U32
N7285_05175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7285_05190	COG1720	tRNA m6t6A37 methyltransferase activity
N7285_05200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N7285_05215	COG0642	Histidine kinase
N7285_05225	COG0494	nUDIX hydrolase
N7285_05235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7285_05240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7285_05245	COG3139	Protein of unknown function (DUF1315)
N7285_05250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N7285_05255	COG1301	dicarboxylic acid transport
N7285_05260	COG1960	acyl-CoA dehydrogenase activity
N7285_05265	COG2819	hydrolase of the alpha beta superfamily
N7285_05275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7285_05285	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7285_05290	COG1234	tRNA 3'-trailer cleavage
N7285_05320	COG2363	Small membrane protein
N7285_05345	COG0513	Belongs to the DEAD box helicase family
N7285_05355	COG0778	Nitroreductase
N7285_05385	COG1286	toxin biosynthetic process
N7285_05410	COG4783	chaperone-mediated protein folding
N7285_05415	COG1610	YqeY-like protein
N7285_05515	COG3111	PFAM Bacterial OB fold (BOF) protein
N7285_05540	COG3243	poly(R)-hydroxyalkanoic acid synthase
N7285_05545	COG0786	glutamate:sodium symporter activity
N7285_05555	COG2186	Transcriptional regulator
N7285_05605	COG0477	Major facilitator Superfamily
N7285_05635	COG2985	domain, Protein
N7285_05645	COG2995	paraquat-inducible protein a
N7285_05650	COG3008	intermembrane lipid transfer
N7285_05650	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N7285_05680	COG0488	(ABC) transporter
N7285_05685	COG3173	Aminoglycoside phosphotransferase
N7285_05695	COG2433	Pfam Transposase IS66
N7285_05735	COG1301	dicarboxylic acid transport
N7285_05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7285_05750	COG2011	ABC-type metal ion transport system permease component
N7285_05755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7285_05760	COG1464	Belongs to the NlpA lipoprotein family
N7285_05765	COG0151	Belongs to the GarS family
N7285_05770	COG0138	bifunctional purine biosynthesis protein purh
N7285_05775	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N7285_05805	COG2308	Evidence 4 Homologs of previously reported genes of
N7285_05815	COG1305	Transglutaminase-like
N7285_05825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7285_05830	COG0305	Participates in initiation and elongation during chromosome replication
N7285_05855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7285_05865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7285_05870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7285_05895	COG0726	polysaccharide deacetylase
N7285_05895	COG1649	PFAM Uncharacterised BCR, COG1649
N7285_05900	COG1215	transferase activity, transferring glycosyl groups
N7285_05905	COG3658	cytochrome
N7285_05915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7285_05930	COG0583	DNA-binding transcription factor activity
N7285_05950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7285_05955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7285_05970	COG1960	acyl-CoA dehydrogenase activity
N7285_05975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7285_05980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7285_06005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N7285_06010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N7285_06020	COG2205	protein histidine kinase activity
N7285_06025	COG0745	RESPONSE REGULATOR receiver
N7285_06030	COG0174	glutamine synthetase
N7285_06050	COG0729	surface antigen
N7285_06075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7285_06080	COG2814	Major facilitator Superfamily
N7285_06095	COG0583	DNA-binding transcription factor activity
N7285_06110	COG1187	pseudouridine synthase activity
N7285_06130	COG0802	atpase or kinase
N7285_06135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7285_06145	COG1923	regulation of RNA biosynthetic process
N7285_06150	COG0697	spore germination
N7285_06165	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7285_06175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7285_06180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N7285_06180	COG0519	Catalyzes the synthesis of GMP from XMP
N7285_06185	COG4302	ethanolamine ammonia-lyase activity
N7285_06190	COG4303	Ethanolamine ammonia lyase large subunit
N7285_06195	COG0531	amino acid
N7285_06215	COG1454	alcohol dehydrogenase
N7285_06220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7285_06230	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
N7285_06250	COG0308	aminopeptidase N
N7285_06280	COG1605	Chorismate mutase
N7285_06300	COG1309	transcriptional regulator
N7285_06310	COG0668	transmembrane transport
N7285_06345	COG4773	Receptor
N7285_06365	COG0488	(ABC) transporter
N7285_06370	COG0589	response to stress
N7285_06395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7285_06405	COG3135	benzoate transporter
N7285_06410	COG1522	sequence-specific DNA binding
N7285_06420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7285_06425	COG0583	DNA-binding transcription factor activity
N7285_06435	COG0183	Belongs to the thiolase family
N7285_06445	COG2030	dehydratase
N7285_06450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7285_06465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7285_06475	COG0824	Thioesterase
N7285_06480	COG1454	alcohol dehydrogenase
N7285_06490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7285_06510	COG0069	glutamate synthase activity
N7285_06675	COG5410	chromosome segregation
N7285_06795	COG0739	heme binding
N7285_06860	COG2814	Major facilitator Superfamily
N7285_06875	COG0511	ligase activity, forming carbon-carbon bonds
N7285_06895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7285_06895	COG1116	anion transmembrane transporter activity
N7285_06900	COG0745	RESPONSE REGULATOR receiver
N7285_06910	COG2146	nitrite reductase [NAD(P)H] activity
N7285_06910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7285_06915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7285_06920	COG0243	molybdopterin cofactor binding
N7285_06930	COG0243	molybdopterin cofactor binding
N7285_06935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7285_06950	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7285_06950	COG0315	cyclic pyranopterin monophosphate synthase activity
N7285_06955	COG0303	'Molybdopterin
N7285_06965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7285_06970	COG0697	spore germination
N7285_06990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N7285_06995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7285_07050	COG2204	response regulator
N7285_07055	COG3852	Histidine kinase
N7285_07075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7285_07080	COG0575	Belongs to the CDS family
N7285_07115	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7285_07135	COG2137	regulation of response to DNA damage stimulus
N7285_07145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N7285_07150	COG1011	Hydrolase
N7285_07175	COG1522	sequence-specific DNA binding
N7285_07185	COG1113	amino acid transport
N7285_07205	COG0659	secondary active sulfate transmembrane transporter activity
N7285_07210	COG2135	peptidase activity
N7285_07225	COG5001	Diguanylate cyclase
N7285_07225	COG3300	MHYT domain
N7285_07245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N7285_07245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7285_07245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7285_07250	COG1105	Belongs to the carbohydrate kinase PfkB family
N7285_07255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7285_07255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7285_07285	COG0024	Methionine aminopeptidase
N7285_07290	COG0583	DNA-binding transcription factor activity
N7285_07300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N7285_07305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7285_07310	COG0516	GMP reductase activity
N7285_07310	COG0517	IMP dehydrogenase activity
N7285_07335	COG0552	protein localization to endoplasmic reticulum
N7285_07345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N7285_07360	COG4890	Cyd operon protein YbgT
N7285_07365	COG1294	oxidase, subunit
N7285_07380	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7285_07390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7285_07395	COG4774	siderophore transport
N7285_07410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7285_07415	COG0569	domain protein
N7285_07420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7285_07450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N7285_07455	COG0542	response to heat
N7285_07480	COG1902	pentaerythritol trinitrate reductase activity
N7285_07480	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7285_07525	COG2323	membrane
N7285_07530	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7285_07540	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7285_07545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7285_07550	COG0183	Belongs to the thiolase family
N7285_07555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7285_07560	COG0596	Alpha beta hydrolase
N7285_07565	COG2271	Major facilitator Superfamily
N7285_07570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7285_07575	COG3485	protocatechuate 3,4-dioxygenase
N7285_07580	COG3485	protocatechuate 3,4-dioxygenase
N7285_07585	COG0710	3-dehydroquinate dehydratase activity
N7285_07590	COG3420	alginic acid biosynthetic process
N7285_07595	COG3659	wide pore channel activity
N7285_07600	COG4993	Dehydrogenase
N7285_07610	COG2391	methyltransferase activity
N7285_07625	COG1414	Transcriptional regulator
N7285_07630	COG0583	DNA-binding transcription factor activity
N7285_07635	COG1960	acyl-CoA dehydrogenase activity
N7285_07660	COG2814	Major facilitator Superfamily
N7285_07670	COG0154	amidase activity
N7285_07690	COG4638	Rieske (2fe-2S)
N7285_07700	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_07710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7285_07720	COG3733	amine oxidase
N7285_07730	COG1012	belongs to the aldehyde dehydrogenase family
N7285_07740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7285_07745	COG0183	Belongs to the thiolase family
N7285_07750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7285_07755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7285_07765	COG4829	muconolactone delta-isomerase
N7285_07770	COG4948	Mandelate Racemase Muconate Lactonizing
N7285_07775	COG0583	DNA-binding transcription factor activity
N7285_07785	COG2186	Transcriptional regulator
N7285_07805	COG1012	belongs to the aldehyde dehydrogenase family
N7285_07825	COG1960	acyl-CoA dehydrogenase activity
N7285_07830	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_07835	COG3829	transcription factor binding
N7285_07845	COG3162	membrane
N7285_07860	COG1012	belongs to the aldehyde dehydrogenase family
N7285_07875	COG0753	catalase activity
N7285_07895	COG1846	Transcriptional regulator
N7285_07900	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7285_07900	COG1902	pentaerythritol trinitrate reductase activity
N7285_07910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7285_07940	COG1309	transcriptional regulator
N7285_07950	COG1335	isochorismatase
N7285_07955	COG0583	DNA-binding transcription factor activity
N7285_07965	COG0475	glutathione-regulated potassium exporter activity
N7285_07965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7285_07975	COG1473	amidohydrolase
N7285_07985	COG2831	hemolysin activation secretion protein
N7285_07990	COG3210	domain, Protein
N7285_08020	COG2188	Transcriptional regulator
N7285_08035	COG0583	DNA-binding transcription factor activity
N7285_08065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7285_08095	COG1566	PFAM secretion protein HlyD family protein
N7285_08110	COG1012	belongs to the aldehyde dehydrogenase family
N7285_08115	COG0129	dihydroxy-acid dehydratase activity
N7285_08125	COG0583	DNA-binding transcription factor activity
N7285_08130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7285_08140	COG2084	Dehydrogenase
N7285_08145	COG2207	Transcriptional regulator
N7285_08160	COG1064	alcohol dehydrogenase
N7285_08170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7285_08175	COG1120	ATPase activity
N7285_08195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7285_08320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N7285_08370	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_08385	COG2207	Transcriptional regulator
N7285_08395	COG2205	protein histidine kinase activity
N7285_08400	COG0745	RESPONSE REGULATOR receiver
N7285_08405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_08410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7285_08415	COG1538	Outer membrane efflux protein
N7285_08425	COG2072	flavoprotein involved in K transport
N7285_08445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7285_08465	COG3539	Fimbrial protein
N7285_08495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N7285_08505	COG0753	catalase activity
N7285_08520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7285_08580	COG1535	isochorismatase
N7285_08580	COG3433	isochorismatase activity
N7285_08585	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_08590	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N7285_08595	COG4149	molybdate abc transporter
N7285_08600	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7285_08610	COG4638	Rieske (2fe-2S)
N7285_08615	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N7285_08620	COG0543	2 iron, 2 sulfur cluster binding
N7285_08620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7285_08645	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_08660	COG2207	Transcriptional regulator
N7285_08670	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_08675	COG2610	gluconate transmembrane transporter activity
N7285_08685	COG0583	DNA-binding transcription factor activity
N7285_08695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7285_08700	COG2031	fatty acid transporter
N7285_08705	COG0183	Belongs to the thiolase family
N7285_08710	COG0583	DNA-binding transcription factor activity
N7285_08715	COG0583	DNA-binding transcription factor activity
N7285_08730	COG1027	Aspartate ammonia-lyase
N7285_08740	COG0477	Major facilitator Superfamily
N7285_08760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7285_08765	COG4521	taurine ABC transporter
N7285_08780	COG2188	Transcriptional regulator
N7285_08790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7285_08795	COG1733	regulation of RNA biosynthetic process
N7285_08800	COG2207	Transcriptional regulator
N7285_08800	COG3708	Transcriptional regulator
N7285_08815	COG0730	response to heat
N7285_08830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7285_08830	COG3453	Protein conserved in bacteria
N7285_08840	COG3781	membrane
N7285_08845	COG1063	alcohol dehydrogenase
N7285_08855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7285_08860	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7285_08865	COG0022	dehydrogenase e1 component
N7285_08870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7285_08875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7285_08890	COG3706	GGDEF domain
N7285_08905	COG0133	tryptophan synthase activity
N7285_08915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7285_08950	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7285_08975	COG2226	methyltransferase
N7285_09030	COG0842	Transport permease protein
N7285_09035	COG0842	Transport permease protein
N7285_09040	COG1131	(ABC) transporter
N7285_09055	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N7285_09060	COG4773	Receptor
N7285_09080	COG0730	response to heat
N7285_09085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N7285_09105	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N7285_09120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7285_09160	COG4264	IucA IucC family
N7285_09165	COG4264	IucA IucC family
N7285_09185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7285_09200	COG1960	acyl-CoA dehydrogenase activity
N7285_09205	COG1960	acyl-CoA dehydrogenase activity
N7285_09210	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7285_09215	COG2207	Transcriptional regulator
N7285_09220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7285_09225	COG0776	regulation of translation
N7285_09250	COG0822	iron-sulfur transferase activity
N7285_09255	COG0316	Belongs to the HesB IscA family
N7285_09285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7285_09305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7285_09310	COG0702	epimerase
N7285_09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7285_09355	COG0339	signal peptide processing
N7285_09405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N7285_09410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N7285_09440	COG0776	regulation of translation
N7285_09505	COG0084	hydrolase, TatD family'
N7285_09525	COG1663	tetraacyldisaccharide 4'-kinase activity
N7285_09530	COG1132	(ABC) transporter
N7285_09540	COG0811	peptide transport
N7285_09545	COG1475	DNA binding
N7285_09550	COG1192	Involved in chromosome partitioning
N7285_09560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7285_09575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7285_09580	COG0191	fructose-bisphosphate aldolase activity
N7285_09600	COG0424	maF-like protein
N7285_09605	COG2850	peptidyl-arginine hydroxylation
N7285_09615	COG0640	Transcriptional regulator
N7285_09630	COG3619	membrane
N7285_09635	COG3122	Protein conserved in bacteria
N7285_09640	COG1132	(ABC) transporter
N7285_09660	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7285_09665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7285_09675	COG0506	proline dehydrogenase activity
N7285_09675	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N7285_09675	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N7285_09680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N7285_09695	COG3698	Phosphodiester glycosidase
N7285_09705	COG2353	YceI-like domain
N7285_09715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7285_09760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N7285_09760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N7285_09785	COG3539	Fimbrial protein
N7285_09790	COG3121	Chaperone
N7285_09815	COG0697	spore germination
N7285_09825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7285_09835	COG0583	DNA-binding transcription factor activity
N7285_09855	COG1309	transcriptional regulator
N7285_09870	COG1522	sequence-specific DNA binding
N7285_09880	COG1126	abc transporter atp-binding protein
N7285_09885	COG0765	amino acid transport
N7285_09890	COG0765	amino acid transport
N7285_09920	COG1464	Belongs to the NlpA lipoprotein family
N7285_09930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7285_09935	COG2011	ABC-type metal ion transport system permease component
N7285_09940	COG0012	GTP binding
N7285_09965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N7285_10005	COG0386	Belongs to the glutathione peroxidase family
N7285_10015	COG0436	Aminotransferase
N7285_10055	COG3634	alkyl hydroperoxide reductase activity
N7285_10070	COG0583	DNA-binding transcription factor activity
N7285_10075	COG0798	PFAM Bile acid sodium symporter
N7285_10080	COG0640	Transcriptional regulator
N7285_10095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7285_10105	COG0583	DNA-binding transcription factor activity
N7285_10115	COG1953	Uracil, thiamine, allantoin
N7285_10125	COG2175	clavaminate synthase activity
N7285_10130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7285_10135	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
N7285_10140	COG4521	taurine ABC transporter
N7285_10150	COG0477	Major facilitator Superfamily
N7285_10170	COG1271	oxidase subunit
N7285_10175	COG1294	oxidase, subunit
N7285_10185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7285_10205	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7285_10225	COG3052	prosthetic group binding
N7285_10230	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N7285_10240	COG2814	Major facilitator Superfamily
N7285_10260	COG1346	cytolysis
N7285_10270	COG0583	DNA-binding transcription factor activity
N7285_10275	COG0625	glutathione transferase activity
N7285_10280	COG0625	glutathione transferase activity
N7285_10285	COG0583	DNA-binding transcription factor activity
N7285_10300	COG1045	serine acetyltransferase
N7285_10305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7285_10310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7285_10320	COG1280	lysine exporter protein (LysE YggA)
N7285_10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7285_10340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7285_10345	COG1126	abc transporter atp-binding protein
N7285_10350	COG0765	amino acid transport
N7285_10355	COG0765	amino acid transport
N7285_10375	COG2205	protein histidine kinase activity
N7285_10375	COG0784	Response regulator, receiver
N7285_10395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7285_10415	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_10465	COG0583	DNA-binding transcription factor activity
N7285_10485	COG0318	PFAM AMP-dependent synthetase and ligase
N7285_10490	COG1309	transcriptional regulator
N7285_10495	COG1960	acyl-CoA dehydrogenase activity
N7285_10500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7285_10505	COG1024	Enoyl-CoA hydratase
N7285_10510	COG4770	biotin carboxylase activity
N7285_10520	COG0583	DNA-binding transcription factor activity
N7285_10535	COG1960	acyl-CoA dehydrogenase activity
N7285_10545	COG2814	Major facilitator Superfamily
N7285_10555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7285_10560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7285_10565	COG2814	Major facilitator Superfamily
N7285_10570	COG1960	acyl-CoA dehydrogenase activity
N7285_10575	COG1024	Enoyl-CoA hydratase
N7285_10580	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_10585	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7285_10590	COG0183	Belongs to the thiolase family
N7285_10600	COG2814	Major facilitator Superfamily
N7285_10610	COG1024	Enoyl-CoA hydratase
N7285_10625	COG1960	acyl-CoA dehydrogenase activity
N7285_10630	COG2814	Major facilitator Superfamily
N7285_10635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7285_10640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7285_10655	COG3842	ATPase activity
N7285_10660	COG1840	ABC-type Fe3 transport system, periplasmic component
N7285_10670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7285_10675	COG1414	Transcriptional regulator
N7285_10685	COG0583	DNA-binding transcription factor activity
N7285_10690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7285_10695	COG1012	belongs to the aldehyde dehydrogenase family
N7285_10705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N7285_10715	COG1012	belongs to the aldehyde dehydrogenase family
N7285_10720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7285_10725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7285_10730	COG2267	carboxylic ester hydrolase activity
N7285_10750	COG3038	cytochrome b561
N7285_10755	COG0753	catalase activity
N7285_10785	COG2050	protein possibly involved in aromatic compounds catabolism
N7285_10795	COG3327	negative regulation of DNA-templated transcription, initiation
N7285_10800	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N7285_10805	COG0183	Belongs to the thiolase family
N7285_10810	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7285_10815	COG1024	Enoyl-CoA hydratase
N7285_10820	COG1024	Enoyl-CoA hydratase
N7285_10825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7285_10830	COG2151	metal-sulfur cluster biosynthetic enzyme
N7285_10835	COG3396	Phenylacetate-CoA oxygenase
N7285_10840	COG3460	Phenylacetate-CoA oxygenase
N7285_10845	COG3396	Phenylacetate-CoA oxygenase
N7285_10850	COG2030	dehydratase
N7285_10850	COG1012	belongs to the aldehyde dehydrogenase family
N7285_10855	COG1760	l-serine dehydratase
N7285_10860	COG0531	amino acid
N7285_10865	COG1012	belongs to the aldehyde dehydrogenase family
N7285_10880	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7285_10890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7285_10910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7285_10920	COG0789	Transcriptional regulator
N7285_10935	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7285_10950	COG2807	transmembrane transport
N7285_10955	COG0590	tRNA wobble adenosine to inosine editing
N7285_11075	COG1116	anion transmembrane transporter activity
N7285_11080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7285_11090	COG0864	Transcriptional regulator
N7285_11110	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7285_11115	COG0439	Biotin carboxylase
N7285_11130	COG1063	alcohol dehydrogenase
N7285_11140	COG1309	transcriptional regulator
N7285_11160	COG0038	chloride channel
N7285_11165	COG4770	biotin carboxylase activity
N7285_11185	COG1914	H( )-stimulated, divalent metal cation uptake system
N7285_11190	COG0583	DNA-binding transcription factor activity
N7285_11240	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7285_11260	COG2814	Major facilitator Superfamily
N7285_11275	COG1560	Kdo2-lipid A biosynthetic process
N7285_11285	COG5006	permease, DMT superfamily
N7285_11290	COG1522	sequence-specific DNA binding
N7285_11305	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N7285_11315	COG4122	O-methyltransferase activity
N7285_11345	COG1538	Outer membrane efflux protein
N7285_11350	COG1137	ATPase activity
N7285_11355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N7285_11365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
N7285_11370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N7285_11370	COG0517	IMP dehydrogenase activity
N7285_11405	COG2814	Major facilitator Superfamily
N7285_11440	COG1278	Cold shock
N7285_11445	COG1280	lysine exporter protein (LysE YggA)
N7285_11475	COG1570	exodeoxyribonuclease VII activity
N7285_11525	COG0583	DNA-binding transcription factor activity
N7285_11535	COG4638	Rieske (2fe-2S)
N7285_11540	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N7285_11545	COG0543	2 iron, 2 sulfur cluster binding
N7285_11545	COG0633	Ferredoxin
N7285_11550	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_11555	COG3135	benzoate transporter
N7285_11560	COG2814	Major facilitator Superfamily
N7285_11575	COG1643	Atp-dependent helicase
N7285_11580	COG0450	alkyl hydroperoxide reductase
N7285_11590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N7285_11600	COG3634	alkyl hydroperoxide reductase activity
N7285_11620	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7285_11625	COG0625	glutathione transferase activity
N7285_11635	COG2885	chlorophyll binding
N7285_11670	COG0542	response to heat
N7285_11685	COG1765	OsmC-like protein
N7285_11705	COG0667	Aldo Keto reductase
N7285_11720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N7285_11730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7285_11740	COG0527	aspartate kinase activity
N7285_11750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7285_11760	COG3038	cytochrome b561
N7285_11765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N7285_11770	COG2252	PERMEase
N7285_11780	COG2072	flavoprotein involved in K transport
N7285_11795	COG1741	Belongs to the pirin family
N7285_11800	COG1309	transcriptional regulator
N7285_11825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7285_11865	COG1902	pentaerythritol trinitrate reductase activity
N7285_11865	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7285_11875	COG2203	Gaf domain
N7285_11875	COG3706	GGDEF domain
N7285_11875	COG4251	negative regulation of phosphorylation
N7285_11875	COG5001	Diguanylate cyclase
N7285_11885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7285_11905	COG4172	Belongs to the ABC transporter superfamily
N7285_11910	COG4239	(ABC) transporter, permease
N7285_11915	COG4174	ABC transporter (Permease)
N7285_11925	COG1388	LysM domain
N7285_11925	COG0741	lytic transglycosylase activity
N7285_11925	COG1388	LysM domain
N7285_11925	COG0741	lytic transglycosylase activity
N7285_11930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7285_11970	COG0583	DNA-binding transcription factor activity
N7285_11975	COG1279	arginine transmembrane transporter activity
N7285_11995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7285_12000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7285_12005	COG0006	proline dipeptidase activity
N7285_12045	COG2194	sulfuric ester hydrolase activity
N7285_12090	COG0739	heme binding
N7285_12420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7285_12445	COG3384	dioxygenase
N7285_12455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7285_12460	COG2878	Part of a membrane complex involved in electron transport
N7285_12465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N7285_12490	COG0768	penicillin binding
N7285_12495	COG0742	ribosomal rna small subunit methyltransferase
N7285_12510	COG0830	nickel cation binding
N7285_12520	COG0804	urea catabolic process
N7285_12560	COG1253	flavin adenine dinucleotide binding
N7285_12565	COG2851	Citrate transporter
N7285_12620	COG1773	rubredoxin
N7285_12625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7285_12635	COG0583	DNA-binding transcription factor activity
N7285_12660	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
N7285_12665	COG4181	ATPase activity
N7285_12710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7285_12730	COG0306	phosphate transporter
N7285_12740	COG3958	Transketolase
N7285_12745	COG3959	Transketolase, thiamine diphosphate binding domain
N7285_12750	COG2271	Major facilitator Superfamily
N7285_12755	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_12760	COG0583	DNA-binding transcription factor activity
N7285_12775	COG2223	nitrite transmembrane transporter activity
N7285_12780	COG2207	Transcriptional regulator
N7285_12785	COG2066	Belongs to the glutaminase family
N7285_12790	COG0242	peptide deformylase activity
N7285_12795	COG0477	Major facilitator Superfamily
N7285_12805	COG0028	Belongs to the TPP enzyme family
N7285_12820	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_12825	COG2267	carboxylic ester hydrolase activity
N7285_12835	COG2271	Major facilitator Superfamily
N7285_12840	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7285_12850	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_12870	COG1414	Transcriptional regulator
N7285_12885	COG1024	Enoyl-CoA hydratase
N7285_12895	COG1215	transferase activity, transferring glycosyl groups
N7285_12900	COG0726	polysaccharide deacetylase
N7285_12900	COG1649	PFAM Uncharacterised BCR, COG1649
N7285_12910	COG4681	YaeQ
N7285_12920	COG0523	cobalamin synthesis protein
N7285_12930	COG1607	acyl-coa hydrolase
N7285_12940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7285_12945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7285_12950	COG1309	transcriptional regulator
N7285_12975	COG2040	homocysteine
N7285_12980	COG0531	amino acid
N7285_13035	COG1595	DNA-templated transcription, initiation
N7285_13045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7285_13050	COG0477	Major facilitator Superfamily
N7285_13070	COG0084	hydrolase, TatD family'
N7285_13105	COG0629	single-stranded DNA binding
N7285_13160	COG0582	viral genome integration into host DNA
N7285_13265	COG0592	DNA-directed DNA polymerase activity
N7285_13305	COG2026	Addiction module toxin, RelE StbE family
N7285_13445	COG1484	DNA-dependent DNA replication
N7285_13535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7285_13605	COG0405	Gamma-glutamyltransferase
N7285_13610	COG2814	Major facilitator Superfamily
N7285_13620	COG2050	protein possibly involved in aromatic compounds catabolism
N7285_13635	COG1090	epimerase
N7285_13655	COG0420	3'-5' exonuclease activity
N7285_13680	COG0735	belongs to the Fur family
N7285_13685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N7285_13705	COG0121	glutamine amidotransferase
N7285_13720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7285_13730	COG0210	DNA helicase
N7285_13735	COG2885	chlorophyll binding
N7285_13740	COG0204	Acyl-transferase
N7285_13755	COG2894	cell division
N7285_13775	COG1280	lysine exporter protein (LysE YggA)
N7285_13780	COG1674	ftsk spoiiie
N7285_13780	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7285_13785	COG0492	ferredoxin-NADP+ reductase activity
N7285_13790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N7285_13800	COG0456	acetyltransferase
N7285_13845	COG1981	membrane
N7285_13860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7285_13860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7285_13880	COG1012	belongs to the aldehyde dehydrogenase family
N7285_13890	COG0657	acetylesterase activity
N7285_13900	COG0473	3-isopropylmalate dehydrogenase activity
N7285_13905	COG0583	DNA-binding transcription factor activity
N7285_13925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N7285_13950	COG0564	pseudouridine synthase activity
N7285_13960	COG0358	DNA primase activity
N7285_13975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N7285_14005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7285_14035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7285_14045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7285_14045	COG0352	thiamine-phosphate diphosphorylase activity
N7285_14045	COG0351	phosphomethylpyrimidine kinase
N7285_14050	COG1652	LysM domain
N7285_14075	COG1399	metal-binding, possibly nucleic acid-binding protein
N7285_14080	COG3101	peptidyl-lysine hydroxylation
N7285_14085	COG0009	L-threonylcarbamoyladenylate synthase
N7285_14090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7285_14095	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7285_14110	COG4106	trans-aconitate 2-methyltransferase activity
N7285_14125	COG2226	methyltransferase
N7285_14125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7285_14125	COG0596	Alpha beta hydrolase
N7285_14130	COG1877	trehalose-phosphatase activity
N7285_14135	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N7285_14140	COG2223	nitrite transmembrane transporter activity
N7285_14160	COG1196	nuclear chromosome segregation
N7285_14170	COG0730	response to heat
N7285_14185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7285_14195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7285_14245	COG0489	protein tyrosine kinase activity
N7285_14255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7285_14255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7285_14285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
N7285_14290	COG2081	HI0933 family
N7285_14300	COG0668	transmembrane transport
N7285_14320	COG0583	DNA-binding transcription factor activity
N7285_14340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N7285_14345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7285_14375	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N7285_14415	COG0745	RESPONSE REGULATOR receiver
N7285_14435	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7285_14445	COG2205	protein histidine kinase activity
N7285_14515	COG4993	Dehydrogenase
N7285_14540	COG0384	phenazine biosynthesis protein PhzF
N7285_14565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7285_14580	COG0583	DNA-binding transcription factor activity
N7285_14610	COG0583	DNA-binding transcription factor activity
N7285_14625	COG0583	DNA-binding transcription factor activity
N7285_14630	COG1053	succinate dehydrogenase
N7285_14640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7285_14645	COG2814	Major facilitator Superfamily
N7285_14650	COG1960	acyl-CoA dehydrogenase activity
N7285_14655	COG0583	DNA-binding transcription factor activity
N7285_14660	COG1063	alcohol dehydrogenase
N7285_14690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N7285_14695	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7285_14700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7285_14715	COG3667	copper resistance
N7285_14720	COG2132	Multicopper oxidase
N7285_14730	COG0561	phosphatase activity
N7285_14735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N7285_14760	COG1214	PFAM Peptidase M22, glycoprotease
N7285_14815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7285_14825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7285_14830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7285_14835	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7285_14895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7285_14905	COG1846	Transcriptional regulator
N7285_14910	COG1764	response to oxidative stress
N7285_14960	COG0037	tRNA processing
N7285_14970	COG0248	Ppx GppA phosphatase
N7285_15000	COG0072	phenylalanine-tRNA ligase activity
N7285_15045	COG1238	metal cluster binding
N7285_15050	COG0625	glutathione transferase activity
N7285_15065	COG0318	PFAM AMP-dependent synthetase and ligase
N7285_15070	COG3028	Belongs to the UPF0307 family
N7285_15075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7285_15095	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7285_15100	COG0617	tRNA 3'-terminal CCA addition
N7285_15105	COG1555	photosystem II stabilization
N7285_15110	COG3956	TIGRFAM MazG family protein
N7285_15120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7285_15140	COG0784	Response regulator, receiver
N7285_15140	COG2205	protein histidine kinase activity
N7285_15140	COG5002	protein histidine kinase activity
N7285_15145	COG1024	Enoyl-CoA hydratase
N7285_15150	COG2084	Dehydrogenase
N7285_15155	COG3622	Belongs to the hyi family
N7285_15185	COG0697	spore germination
N7285_15195	COG2814	Major facilitator Superfamily
N7285_15200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7285_15210	COG0583	DNA-binding transcription factor activity
N7285_15220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N7285_15235	COG0084	hydrolase, TatD family'
N7285_15250	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N7285_15280	COG0440	acetolactate synthase activity
N7285_15285	COG0028	Belongs to the TPP enzyme family
N7285_15310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_15315	COG0577	efflux transmembrane transporter activity
N7285_15315	COG1136	(ABC) transporter
N7285_15320	COG1538	Outer membrane efflux protein
N7285_15335	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N7285_15340	COG1162	GTPase activity
N7285_15350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N7285_15370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7285_15375	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_15415	COG2986	histidine ammonia-lyase
N7285_15430	COG0318	PFAM AMP-dependent synthetase and ligase
N7285_15440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7285_15485	COG1426	Protein conserved in bacteria
N7285_15520	COG0793	Belongs to the peptidase S41A family
N7285_15535	COG2267	carboxylic ester hydrolase activity
N7285_15545	COG1012	belongs to the aldehyde dehydrogenase family
N7285_15550	COG3265	gluconokinase activity
N7285_15560	COG0800	Aldolase
N7285_15575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N7285_15580	COG0280	phosphate acetyltransferase
N7285_15580	COG0857	belongs to the CobB CobQ family
N7285_15585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N7285_15585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N7285_15605	COG0740	serine-type endopeptidase activity
N7285_15615	COG4774	siderophore transport
N7285_15625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7285_15635	COG2813	Specifically methylates the guanine in position
N7285_15635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N7285_15735	COG0788	formyltetrahydrofolate deformylase activity
N7285_15760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7285_15760	COG4651	solute:proton antiporter activity
N7285_15780	COG0724	RNA recognition motif
N7285_15785	COG0210	DNA helicase
N7285_15810	COG1733	regulation of RNA biosynthetic process
N7285_15820	COG2900	Belongs to the SlyX family
N7285_15825	COG0488	(ABC) transporter
N7285_15830	COG1280	lysine exporter protein (LysE YggA)
N7285_15835	COG1560	Kdo2-lipid A biosynthetic process
N7285_15845	COG1301	dicarboxylic acid transport
N7285_15900	COG0473	3-isopropylmalate dehydrogenase activity
N7285_15965	COG0583	DNA-binding transcription factor activity
N7285_15975	COG0625	glutathione transferase activity
N7285_15980	COG2378	regulation of single-species biofilm formation
N7285_15985	COG0546	phosphoglycolate phosphatase activity
N7285_15995	COG1530	ribonuclease E activity
N7285_16000	COG0318	PFAM AMP-dependent synthetase and ligase
N7285_16015	COG0583	DNA-binding transcription factor activity
N7285_16020	COG4221	oxidoreductase activity
N7285_16025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7285_16035	COG0534	Mate efflux family protein
N7285_16050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N7285_16090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N7285_16095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7285_16110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7285_16120	COG0644	oxidoreductase
N7285_16120	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
N7285_16125	COG0425	Belongs to the sulfur carrier protein TusA family
N7285_16130	COG4535	Mg2 and Co2 transporter CorC
N7285_16140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7285_16160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7285_16165	COG0475	glutathione-regulated potassium exporter activity
N7285_16165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7285_16170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N7285_16180	COG0484	heat shock protein binding
N7285_16185	COG0789	Transcriptional regulator
N7285_16190	COG0598	Magnesium transport protein CorA
N7285_16205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7285_16210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7285_16215	COG1074	ATP-dependent DNA helicase activity
N7285_16220	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N7285_16240	COG2226	methyltransferase
N7285_16255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7285_16260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7285_16275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7285_16275	COG2111	Na H antiporter
N7285_16280	COG1006	Multisubunit Na H antiporter MnhC subunit
N7285_16285	COG0651	ATP synthesis coupled electron transport
N7285_16290	COG1863	multisubunit Na H antiporter MnhE subunit
N7285_16295	COG2212	antiporter activity
N7285_16300	COG1320	monovalent cation:proton antiporter activity
N7285_16315	COG0195	Participates in both transcription termination and antitermination
N7285_16365	COG0237	dephospho-CoA kinase activity
N7285_16375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7285_16390	COG0497	DNA recombination
N7285_16400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7285_16430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7285_16430	COG2169	Transcriptional regulator
N7285_16435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7285_16500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7285_16515	COG0326	Molecular chaperone. Has ATPase activity
N7285_16530	COG2056	Na+-H+ antiporter family
N7285_16535	COG0596	Alpha beta hydrolase
N7285_16630	COG0546	phosphoglycolate phosphatase activity
N7285_16635	COG1716	ATPase activity
N7285_16680	COG0181	hydroxymethylbilane synthase activity
N7285_16690	COG3275	phosphorelay sensor kinase activity
N7285_16710	COG1538	Outer membrane efflux protein
N7285_16715	COG0697	spore germination
N7285_16740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N7285_16745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7285_16750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7285_16755	COG0772	Belongs to the SEDS family
N7285_16780	COG4974	Belongs to the 'phage' integrase family
N7285_16785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7285_16795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7285_16805	COG2197	response regulator
N7285_16820	COG0793	Belongs to the peptidase S41A family
N7285_16825	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N7285_16830	COG0795	lipopolysaccharide-transporting ATPase activity
N7285_16870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7285_16870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7285_16880	COG0004	ammonium transporteR
N7285_16885	COG0347	Belongs to the P(II) protein family
N7285_16960	COG1061	Type III restriction enzyme res subunit
N7285_16965	COG1002	Type II restriction enzyme, methylase subunits
N7285_16975	COG0659	secondary active sulfate transmembrane transporter activity
N7285_16980	COG0589	response to stress
N7285_17025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7285_17045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N7285_17060	COG0318	PFAM AMP-dependent synthetase and ligase
N7285_17070	COG0477	Major facilitator Superfamily
N7285_17075	COG2860	membrane
N7285_17085	COG1253	flavin adenine dinucleotide binding
N7285_17105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7285_17145	COG0655	NAD(P)H dehydrogenase (quinone) activity
N7285_17155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7285_17225	COG0758	DNA mediated transformation
N7285_17235	COG0697	spore germination
N7285_17240	COG1309	transcriptional regulator
N7285_17255	COG0386	Belongs to the glutathione peroxidase family
N7285_17320	COG1121	(ABC) transporter
N7285_17325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7285_17330	COG1280	lysine exporter protein (LysE YggA)
N7285_17335	COG2837	iron assimilation
N7285_17345	COG0281	malic enzyme
N7285_17390	COG0519	Catalyzes the synthesis of GMP from XMP
N7285_17390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N7285_17395	COG4399	Belongs to the UPF0754 family
N7285_17400	COG2259	Doxx family
N7285_17405	COG0586	Pfam SNARE associated Golgi protein
N7285_17420	COG1192	Involved in chromosome partitioning
N7285_17430	COG0271	Belongs to the BolA IbaG family
N7285_17450	COG2267	carboxylic ester hydrolase activity
N7285_17470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7285_17470	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N7285_17470	COG3321	synthase
N7285_17470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N7285_17475	COG1960	acyl-CoA dehydrogenase activity
N7285_17485	COG2197	response regulator
N7285_17495	COG3916	Acyl-homoserine-lactone synthase
N7285_17500	COG0477	Major facilitator Superfamily
N7285_17505	COG1024	Enoyl-CoA hydratase
N7285_17510	COG1024	Enoyl-CoA hydratase
N7285_17515	COG1960	acyl-CoA dehydrogenase activity
N7285_17520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7285_17540	COG1113	amino acid transport
N7285_17545	COG1113	amino acid transport
N7285_17550	COG0251	oxidation-reduction process
N7285_17590	COG0564	pseudouridine synthase activity
N7285_17650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7285_17665	COG1802	Transcriptional regulator
N7285_17675	COG1448	Aminotransferase
N7285_17680	COG0277	FAD linked oxidase domain protein
N7285_17690	COG2186	Transcriptional regulator
N7285_17700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7285_17705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7285_17720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7285_17725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N7285_17750	COG0438	transferase activity, transferring glycosyl groups
N7285_17780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N7285_17810	COG0728	peptidoglycan biosynthetic process
N7285_17815	COG3023	N-Acetylmuramoyl-L-alanine amidase
N7285_17875	COG0546	phosphoglycolate phosphatase activity
N7285_17880	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_17900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7285_17905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7285_17910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7285_17915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7285_17920	COG1116	anion transmembrane transporter activity
N7285_17925	COG1309	transcriptional regulator
N7285_17930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7285_17940	COG0196	riboflavin kinase activity
N7285_17945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7285_17955	COG1047	Peptidyl-prolyl cis-trans
N7285_17995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N7285_18000	COG0657	acetylesterase activity
N7285_18020	COG0583	DNA-binding transcription factor activity
N7285_18050	COG2951	lytic endotransglycosylase activity
N7285_18055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7285_18070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7285_18080	COG0671	phosphoesterase, PA-phosphatase related
N7285_18085	COG0861	Integral membrane protein TerC family
N7285_18095	COG0754	glutathionylspermidine amidase activity
N7285_18105	COG0402	S-adenosylhomocysteine deaminase activity
N7285_18120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7285_18125	COG1230	cation diffusion facilitator family transporter
N7285_18140	COG0706	membrane insertase activity
N7285_18165	COG0592	DNA-directed DNA polymerase activity
N7285_18175	COG0187	DNA topoisomerase II activity
N7285_18185	COG0586	Pfam SNARE associated Golgi protein
N7285_18190	COG0488	(ABC) transporter
N7285_18215	COG0596	Alpha beta hydrolase
N7285_18220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N7285_18225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7285_18265	COG0733	neurotransmitter:sodium symporter activity
N7285_18305	COG2233	PERMEase
N7285_18320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7285_18355	COG2814	Major facilitator Superfamily
N7285_18360	COG0656	L-ascorbic acid biosynthetic process
N7285_18365	COG0583	DNA-binding transcription factor activity
N7285_18380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7285_18385	COG1064	alcohol dehydrogenase
N7285_18390	COG2818	Glycosylase
N7285_18405	COG1194	a g-specific adenine glycosylase
N7285_18425	COG2983	Belongs to the UPF0260 family
N7285_18430	COG2133	pyrroloquinoline quinone binding
N7285_18435	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7285_18440	COG2116	formate transmembrane transporter activity
N7285_18460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7285_18465	COG1335	isochorismatase
N7285_18470	COG0385	Bile acid
N7285_18475	COG0534	Mate efflux family protein
N7285_18480	COG1683	Conserved Protein
N7285_18500	COG0625	glutathione transferase activity
N7285_18510	COG1113	amino acid transport
N7285_18520	COG0523	cobalamin synthesis protein
N7285_18530	COG2188	Transcriptional regulator
N7285_18560	COG0010	Belongs to the arginase family
N7285_18575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7285_18580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7285_18590	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7285_18595	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N7285_18695	COG0534	Mate efflux family protein
N7285_18700	COG0436	Aminotransferase
N7285_18705	COG2733	membrane
N7285_18720	COG2918	glutathione biosynthetic process
N7285_18735	COG0791	NLP P60 protein
N7285_18735	COG1388	LysM domain
N7285_18750	COG3150	esterase
N7285_18760	COG1028	Short-chain dehydrogenase reductase Sdr
N7285_18765	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N7285_18775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7285_18785	COG2233	PERMEase
N7285_18790	COG2351	hydroxyisourate hydrolase activity
N7285_18825	COG3706	GGDEF domain
N7285_18840	COG1393	Belongs to the ArsC family
N7285_18845	COG0708	Exodeoxyribonuclease III
N7285_18865	COG0189	ligase activity
N7285_18885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7285_18895	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7285_18910	COG4942	peptidase
N7285_18920	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7285_18930	COG2119	membrane
N7285_18935	COG4774	siderophore transport
N7285_18940	COG0426	domain, Protein
N7285_18940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7285_18965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7285_18985	COG1902	pentaerythritol trinitrate reductase activity
N7285_18990	COG1519	Transferase
N7285_18995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N7285_19000	COG0668	transmembrane transport
N7285_19010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7285_19015	COG1335	isochorismatase
N7285_19020	COG1522	sequence-specific DNA binding
N7285_19025	COG3328	transposase activity