locus-tag class description P795_0010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) P795_0020 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) P795_0030 ENOG4105DQR SNARE associated Golgi P795_0035 ENOG4105C5H ABC transporter P795_0040 ENOG4108821 RND type efflux pump P795_0045 ENOG4108821 RND type efflux pump P795_0050 ENOG4108821 RND type efflux pump P795_0060 ENOG4105D74 hydrolase P795_0065 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) P795_0070 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) P795_0095 ENOG4105C8J )-transporter P795_0105 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B P795_0130 ENOG4108W5M transcriptional regulator P795_0135 ENOG4105C2W permease P795_0145 ENOG4108IG5 Transcriptional regulator P795_0150 ENOG4105DJY efflux transporter, rnd family, mfp subunit P795_0185 ENOG4105F27 Major Facilitator P795_0190 ENOG4105CV8 reductase P795_0195 ENOG4105HEI LysR family (Transcriptional regulator P795_0210 ENOG4105DQ4 alcohol dehydrogenase P795_0215 ENOG4108R3E Dna-3-methyladenine glycosylase i P795_0230 ENOG4105CEN a g-specific adenine glycosylase P795_0250 ENOG4108ZZ3 UPF0260 protein P795_0260 ENOG4105D1H recombination factor protein RarA P795_0265 ENOG4105S64 Formate nitrite transporter P795_0285 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) P795_0290 ENOG4108RWI nicotinamidase P795_0295 ENOG4105C09 Bile acid P795_0300 ENOG4107QI1 Mate efflux family protein P795_0305 ENOG4105EWC Purine nucleoside phosphorylase P795_0320 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) P795_0325 ENOG4108RXX maleylacetoacetate isomerase P795_0335 ENOG4105C85 amino acid P795_0345 ENOG4105CKI cobalamin synthesis protein P795_0355 ENOG4105CZE histidine utilization repressor P795_0360 ENOG41090B9 response to stress P795_0375 ENOG4105C85 amino acid P795_0385 ENOG41088SP formiminoglutamate hydrolase P795_0405 ENOG4108NIW Leucine export protein LeuE P795_0415 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) P795_0425 ENOG4108ZAI phosphatidylglycerophosphatase a P795_0430 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) P795_0445 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) P795_0490 ENOG4105KHC sulfurtransferase P795_0520 ENOG4105BZU Histidine kinase P795_0525 ENOG4105CK6 Two component transcriptional regulator (Winged helix family P795_0540 ENOG4107QJQ Mate efflux family protein P795_0545 ENOG4105CHM Aminotransferase P795_0550 ENOG4106BRA Membrane P795_0565 ENOG4105D9M gamma-glutamylcysteine synthetase P795_0575 ENOG4105CS6 Rhs element vgr protein P795_0580 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase P795_0610 ENOG4105IPS esterase P795_0615 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) P795_0625 ENOG4105EWI Short-chain dehydrogenase reductase Sdr P795_0630 ENOG4108Z2U ureidoglycolate hydrolase P795_0640 ENOG41061H0 Monooxygenase P795_0655 ENOG41084YZ Hydrolase P795_0685 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) P795_0690 ENOG4105BZU Histidine kinase P795_0705 ENOG4105KUZ arsenate reductase P795_0710 ENOG4105CGK Exodeoxyribonuclease III P795_0730 ENOG4105D7Z glutathione synthase P795_0750 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) P795_0755 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) P795_0760 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) P795_0775 ENOG41063SB peptidase P795_0780 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) P795_0785 ENOG4107QSN dihydrolipoamide acetyltransferase P795_0800 ENOG4105E0K tonB-dependent siderophore receptor P795_0815 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) P795_0830 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) P795_0845 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) P795_0855 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase P795_0860 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase P795_0870 ENOG4105D64 Mechanosensitive ion channel P795_0880 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) P795_0885 ENOG4108W2Y isochorismatase P795_0895 ENOG4105FBW Monooxygenase P795_0900 ENOG4108UZX fmn reductase P795_0915 ENOG4105BZU Histidine kinase P795_0920 ENOG41062QD Membrane P795_0925 ENOG4107QN1 sodium solute P795_0935 ENOG4105C94 Transporter P795_0945 ENOG4105BZU Histidine kinase P795_0950 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) P795_0955 ENOG4108WUH Transcriptional regulator, TetR family P795_0960 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein P795_0970 ENOG4105RA2 Membrane P795_0975 ENOG4105DWF phosphomethylpyrimidine kinase P795_0985 ENOG4107RDB Major Facilitator P795_0990 ENOG4108UUM single-stranded DNA-binding protein P795_1000 ENOG4108UMN azlc family P795_10000 ENOG4106FTQ Taurine ABC transporter, periplasmic P795_10010 ENOG4105C54 Major Facilitator superfamily P795_10030 ENOG4105C4M (Ubiquinol oxidase) subunit I P795_10035 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii P795_10045 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family P795_10050 ENOG4108K70 Transcriptional regulator P795_10065 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase P795_10070 ENOG4105PSI phosphoribosyl-dephospho-CoA transferase P795_10085 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) P795_10090 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase P795_1010 ENOG4105C85 amino acid P795_10100 ENOG4105ETT transcriptional Regulator, LysR family P795_10110 ENOG4105DXI Major Facilitator superfamily P795_10130 ENOG41067MG lrgb family P795_10135 ENOG4105VAW lrga family P795_10140 ENOG4105CMU LysR family (Transcriptional regulator P795_10145 ENOG4108SHQ Glutathione S-transferase P795_10150 ENOG4105CYM Glutathione S-transferase P795_10155 ENOG4105CBN LysR family transcriptional regulator P795_10160 ENOG4105CHR reductase P795_10170 ENOG4105D7W serine acetyltransferase P795_10175 ENOG4105ESN nucleotide-binding protein P795_10180 ENOG4105C9B Cysteine desulfurase P795_10190 ENOG4105EXG Transcriptional regulator P795_10195 ENOG4105CT1 (ABC) transporter P795_1020 ENOG4108JPW Aminotransferase P795_10200 ENOG4107RP9 extracellular solute-binding protein, family 3 P795_10210 ENOG4108HW4 amino acid AbC transporter P795_10215 ENOG4105EAD ABC transporter P795_10225 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase P795_10230 ENOG4105BZU Histidine kinase P795_10240 ENOG4105EW9 transcriptional regulator AsnC family P795_1025 ENOG4105C26 Dehydrogenase P795_10250 ENOG4105KT5 UmuD protein P795_10270 ENOG4105CYX Short-chain dehydrogenase reductase Sdr P795_10320 ENOG4105HEI LysR family (Transcriptional regulator P795_10340 ENOG4105CEY Amp-dependent synthetase and ligase P795_10345 ENOG4105R8C Transcriptional regulator P795_1035 ENOG4105CHJ isochorismatase hydrolase P795_10350 ENOG4105C1G acyl-Coa dehydrogenase P795_10355 ENOG4107QX3 carboxylase P795_10360 ENOG4105E39 Enoyl-CoA hydratase P795_10375 ENOG4105CC0 LysR family Transcriptional regulator P795_10390 ENOG4105CSU acyl-Coa dehydrogenase P795_1040 ENOG4105EUB pirin domain protein P795_10400 ENOG4105EQ0 Major Facilitator superfamily P795_10410 ENOG4107QNJ CoA-transferase subunit B P795_10415 ENOG4107QP7 CoA-transferase subunit A P795_10420 ENOG4107RGD Major Facilitator superfamily P795_10425 ENOG4105C1G acyl-Coa dehydrogenase P795_10430 ENOG4105E39 Enoyl-CoA hydratase P795_10435 ENOG4105CHR reductase P795_10440 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase P795_10445 ENOG4105CHU acetyl-coa acetyltransferase P795_10455 ENOG4105EQ0 Major Facilitator superfamily P795_10460 ENOG4105EA8 2-Nitropropane dioxygenase P795_10465 ENOG4108UKI Enoyl-CoA hydratase P795_10475 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F P795_10480 ENOG4105C1G acyl-Coa dehydrogenase P795_10485 ENOG4107RGD Major Facilitator superfamily P795_10490 ENOG4108KAZ Involved in phosphonate degradation (By similarity) P795_10495 ENOG4107STF Involved in phosphonate degradation (By similarity) P795_10505 ENOG4107RCV ABC transporter, permease P795_10510 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) P795_10515 ENOG4105C4Y ABC transporter P795_10525 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase P795_10530 ENOG4107HP6 Transcriptional regulator P795_10540 ENOG4105HEI LysR family (Transcriptional regulator P795_10545 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase P795_10550 ENOG4105C26 Dehydrogenase P795_10560 ENOG4105ETS cytosine purines uracil thiamine allantoin P795_10570 ENOG4105C26 Dehydrogenase P795_10575 ENOG4108M8W Monooxygenase P795_10580 ENOG4105MXW flavin reductase domain protein, FMN-binding P795_10585 ENOG4108MXF Alpha Beta Hydrolase P795_10605 ENOG4105CPW cytochrome b561 P795_10610 ENOG4107VGR Catalase P795_10625 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) P795_10630 ENOG4105C4R Atp-dependent dna helicase P795_10640 ENOG4107RRE RNA-directed DNA polymerase P795_10645 ENOG4107YAU phenylacetic acid degradation protein P795_10655 ENOG4105V9J phenylacetic acid degradation operon negative regulatory protein P795_10660 ENOG4105DZS Phenylacetate-CoA ligase P795_10665 ENOG4105CHU acetyl-coa acetyltransferase P795_10670 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase P795_10675 ENOG4108UKI Enoyl-CoA hydratase P795_10680 ENOG4105E39 Enoyl-CoA hydratase P795_10685 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) P795_10690 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit P795_10695 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit P795_10700 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit P795_10705 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit P795_10710 ENOG4105DXM phenylacetic acid degradation protein P795_10715 ENOG4105EJQ L-serine dehydratase P795_10720 ENOG4107QTZ amino acid P795_10725 ENOG4105CZJ Aldehyde dehydrogenase P795_10750 ENOG4105MWK D-amino acid dehydrogenase, small subunit P795_10770 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) P795_10785 ENOG4108Z4X TRANSCRIPTIONal P795_10795 ENOG4105WPN DNA integration recombination invertion protein P795_1080 ENOG4105D94 Major Facilitator Superfamily P795_10810 ENOG4105DJ2 Major Facilitator Superfamily P795_10815 ENOG4107Y2X deaminase P795_10825 ENOG4105EMY transcriptional regulator P795_1085 ENOG4107RSM transcriptional regulator P795_10855 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit P795_10865 ENOG4105UYK outer membrane protein a P795_10990 ENOG4108HW3 (ABC) transporter P795_11000 ENOG4105MRR Transcriptional regulator (By similarity) P795_11015 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF P795_11020 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase P795_11035 ENOG4105E2A Dehydrogenase P795_1105 ENOG4105CPC Aldo Keto reductase P795_11065 ENOG4107R4J Chloride channel P795_11070 ENOG4108JIK carboxylase P795_11090 ENOG4105C5A transporter P795_11095 ENOG4108WAV Transcriptional regulator P795_1110 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) P795_11120 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) P795_11140 ENOG4105D2S major facilitator superfamily P795_11155 ENOG4107QUT magnesium and cobalt transport protein CorA P795_11160 ENOG4105D1S lipid A biosynthesis P795_11165 ENOG4105BZU Histidine kinase P795_11170 ENOG4107AQZ Membrane P795_11195 ENOG4108Z4U Ferredoxin P795_11235 ENOG4105DFG type I secretion outer membrane protein P795_11240 ENOG4108IUZ ABC transporter P795_11245 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA P795_11255 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase P795_11260 ENOG4105C2X Arabinose 5-phosphate isomerase P795_11290 ENOG4107YPT transcriptional regulator P795_11315 ENOG4105II7 pyrroline-5-carboxylate reductase P795_11325 ENOG4105VEQ Cold shock protein P795_11330 ENOG410829K Lysine exporter protein (Lyse ygga) P795_11360 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) P795_1140 ENOG4105KVH Transcriptional regulator P795_11410 ENOG4108KB2 LysR family Transcriptional regulator P795_11415 ENOG4105FUY alpha subunit P795_11420 ENOG4108UKV benzoate 1,2-dioxygenase P795_11425 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein P795_11430 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase P795_11435 ENOG4105DKK Benzoate P795_11440 ENOG4105D2S major facilitator superfamily P795_1145 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein P795_11455 ENOG4105CQ7 ATP-dependent helicase P795_11460 ENOG4105D3R alkyl hydroperoxide reductase P795_11470 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) P795_11480 ENOG4108JU3 Alkyl hydroperoxide reductase P795_11490 ENOG4108K3A Glutathione S-transferase P795_11500 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) P795_11505 ENOG4108TGY Glutathione S-transferase P795_11515 ENOG4108ZG0 Ompa motb domain protein P795_11520 ENOG4105CD3 dihydroorotase P795_11550 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit P795_11565 ENOG4108UKZ OsmC family P795_11570 ENOG4107RYR Transcriptional regulator, Crp Fnr family P795_11575 ENOG4105CPC Aldo Keto reductase P795_11590 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis P795_11600 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase P795_11610 ENOG4105CFH Aspartokinase P795_11620 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) P795_11630 ENOG4105CPW cytochrome b561 P795_11635 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) P795_11640 ENOG4105C7N Xanthine uracil vitamin C permease P795_11650 ENOG4105F95 Monooxygenase P795_11685 ENOG4105F95 Monooxygenase P795_11690 ENOG4105JQZ Methyltransferase P795_11700 ENOG4107RN6 Monooxygenase P795_11720 ENOG4105EPF Outer membrane porin P795_11725 ENOG4105D2S major facilitator superfamily P795_11730 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) P795_11735 ENOG4105E6M Sulphatase-modifying factor protein P795_11750 ENOG4105E3J oxidoreductase P795_11765 ENOG4108SC4 )-transporter P795_11770 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase P795_11785 ENOG4105C1G acyl-Coa dehydrogenase P795_11790 ENOG4105EPF Outer membrane porin P795_11795 ENOG4105NI3 Protein of unknown function (DUF3237) P795_11810 ENOG4105JXH GntR family transcriptional regulator P795_11815 ENOG4105CZJ Aldehyde dehydrogenase P795_11825 ENOG4105EQX glucarate dehydratase P795_11830 ENOG4105DJB Major Facilitator Superfamily P795_11835 ENOG4105CTX dehydratase P795_11840 ENOG4105CTX dehydratase P795_11845 ENOG4105DJP Membrane P795_11865 ENOG4107RGH Aldehyde dehydrogenase P795_11885 ENOG4105CKT filamentous hemagglutinin P795_11890 ENOG4105D5K Hemolysin activator protein P795_11900 ENOG4105C85 amino acid P795_11920 ENOG4105C26 Dehydrogenase P795_11945 ENOG4105CUB amino acid P795_11955 ENOG4105C85 amino acid P795_11965 ENOG4107Y60 (LipO)protein P795_11975 ENOG4106B0W Curli production assembly transport component CsgG P795_11995 ENOG4105D01 (LipO)protein P795_12000 ENOG4108M3P Membrane P795_12010 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase P795_12035 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) P795_1205 ENOG4105CUV Homoserine Kinase P795_12050 ENOG4108JQ5 ABC transporter P795_12055 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component P795_12060 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component P795_12070 ENOG4105E9H Lytic Murein transglycosylase P795_12070 ENOG4105E9H Lytic Murein transglycosylase P795_12075 ENOG4107RZZ dna polymerase iii epsilon subunit P795_12085 ENOG4105E09 nadh pyrophosphatase P795_12095 ENOG4105W4M Transport-associated protein P795_12105 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) P795_12115 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) P795_12120 ENOG4108ZUB Lysine exporter protein (Lyse ygga) P795_12140 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family P795_12145 ENOG4105D0A hydroxylase P795_12150 ENOG4107RAQ aminopeptidase P795_12185 ENOG4105DIJ Phosphoethanolamine transferase P795_12260 ENOG4105E4C Lytic transglycosylase catalytic P795_1245 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) P795_12530 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase P795_12555 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b P795_12570 ENOG4105D82 Glutamate dehydrogenase P795_12575 ENOG4108R3D Electron transport complex P795_12580 ENOG4105CSM endonuclease III P795_12605 ENOG4105CJN penicillin-binding protein P795_12610 ENOG4106H78 methyltransferase P795_12625 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) P795_12635 ENOG4105CQM Urea amidohydrolase subunit alpha P795_1265 ENOG4105CYC Transferase P795_12675 ENOG4107RET Isocitrate lyase P795_12685 ENOG4105C37 (CBS) domain P795_12690 ENOG4105D4T Citrate transporter P795_1270 ENOG4105E0F Histidine kinase P795_12705 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) P795_12715 ENOG4108MRJ P795_12735 ENOG4105VCQ rubredoxin P795_12740 ENOG4107QZF nitrite reductase NADPH large subunit P795_1275 ENOG4105DPZ Two component transcriptional regulator (Winged helix family P795_12750 ENOG4105C5Q Transcriptional regulator P795_12770 ENOG4107U91 Rhomboid family P795_12775 ENOG4105CV6 ABC transporter, permease P795_12780 ENOG4108I0Y (ABC) transporter P795_12785 ENOG4108UJV acyl-CoA thioesterase i P795_12805 ENOG4107RNH Outer membrane receptor FepA P795_12820 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) P795_12825 ENOG4105E6M Sulphatase-modifying factor protein P795_12845 ENOG4105CJ3 phosphate transporter P795_1285 ENOG4105CHH sulfate transporter P795_12850 ENOG4105C3R Methionine synthase P795_12865 ENOG4105CSP Major Facilitator Superfamily P795_12875 ENOG4108PZW LysR family Transcriptional regulator P795_12885 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) P795_12890 ENOG4105EU0 Major facilitator Superfamily P795_12895 ENOG4108R6W Transcriptional regulator, ARAC family P795_1290 ENOG4105PDP Short chain dehydrogenase P795_12900 ENOG4105CSV Glutaminase P795_12905 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) P795_12910 ENOG4105CSH Transporter P795_12920 ENOG4105C7K acetolactate synthase P795_12935 ENOG4105CHR reductase P795_12940 ENOG4108MXF Alpha Beta Hydrolase P795_12950 ENOG4105DJB Major Facilitator Superfamily P795_12965 ENOG4105CHR reductase P795_12985 ENOG41069M3 Transcriptional regulator P795_1300 ENOG4105C5H ABC transporter P795_13000 ENOG4106YT9 Enoyl-CoA hydratase P795_13010 ENOG4105CND Glycosyl transferase, family 2 P795_13015 ENOG4107BJW polysaccharide deacetylase P795_13025 ENOG4108VWS Yaeq family P795_13035 ENOG4105CKI cobalamin synthesis protein P795_13055 ENOG4105C94 Transporter P795_13060 ENOG4105C94 Transporter P795_13065 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) P795_13090 ENOG4107QK5 Homocysteine s-methyltransferase P795_13095 ENOG4105D5Q Arginine ornithine antiporter P795_13120 ENOG4108YNN Heme oxygenase P795_13150 ENOG4108SF5 RNA Polymerase P795_13160 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) P795_13165 ENOG4105C54 Major Facilitator superfamily P795_13190 ENOG4105CVR type I restriction-modification system P795_13195 ENOG4107SCJ type I restriction enzyme EcoKI subunit R P795_13210 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) P795_13215 ENOG4105C0R drug resistance transporter emrb qaca subfamily P795_13220 ENOG4105CW7 secretion protein, HlyD family P795_13225 ENOG4108VUY thioesterase Superfamily protein P795_13230 ENOG4105D52 delta-aminolevulinic acid dehydratase P795_13235 ENOG4105MWK D-amino acid dehydrogenase, small subunit P795_13240 ENOG4105ECP epimerase P795_13260 ENOG4107RH8 nuclease SbcCD subunit D P795_13265 ENOG4105EYH Exonuclease P795_13275 ENOG4105DFA alanine racemase domain protein P795_13280 ENOG4105CZX twitching motility protein P795_13285 ENOG4105CZX twitching motility protein P795_13290 ENOG41090R7 Ferric uptake P795_13315 ENOG4105E7A Glutamine amidotransferase P795_13330 ENOG4107QKV phosphomannomutase P795_13340 ENOG4105C4R Atp-dependent dna helicase P795_13345 ENOG4108ZG0 Ompa motb domain protein P795_13350 ENOG4106HNH Acyl-transferase P795_13365 ENOG4107QMS site-determining protein P795_13390 ENOG4105CNU cell division protein FtsK P795_13395 ENOG4105C3M thioredoxin reductase P795_13400 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) P795_13410 ENOG4105KEG ribosomal-protein-alanine acetyltransferase P795_13460 ENOG4108YXA Membrane P795_13465 ENOG4105EUB pirin domain protein P795_13475 ENOG4105C4K Nad synthetase P795_13485 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding P795_13505 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase P795_13510 ENOG4105C34 Pseudouridine synthase P795_13515 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane P795_13520 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) P795_13535 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) P795_13545 ENOG4105C5T Phosphoribosyl pyrophosphate synthase P795_13575 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) P795_13585 ENOG4105DWF phosphomethylpyrimidine kinase P795_13590 ENOG4109066 lysm domain bon superfamily protein P795_1360 ENOG4108IQI permease P795_13600 ENOG4105CHR reductase P795_13605 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase P795_13615 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein P795_13620 ENOG4108BPE -transporting atpase P795_13625 ENOG4107RTD sua5 ycio yrdc ywlc family protein P795_13630 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) P795_13635 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) P795_13640 ENOG4105FE9 pseudouridine synthase P795_13650 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) P795_13655 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) P795_13665 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) P795_13670 ENOG4108K4C ec 3.1.3.12 P795_13675 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase P795_13680 ENOG4106UW1 Major Facilitator superfamily P795_13700 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) P795_13710 ENOG4105HF0 Membrane P795_13725 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY P795_13735 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) P795_13790 ENOG4105D1F ATP-binding protein P795_1380 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein P795_13800 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) P795_13830 ENOG4105K6H D-cysteine desulfhydrase P795_13835 ENOG4105CBX hi0933 family P795_13860 ENOG4105DP0 ferredoxin-NADP reductase P795_13865 ENOG4105DUM transcriptional regulator, lysR family P795_13885 ENOG4105C8S subunit m P795_13890 ENOG4105D65 subunit l P795_13900 ENOG4107UFS subunit j P795_13915 ENOG4108IEH NADH dehydrogenase subunit g P795_13920 ENOG4107QIZ NADH dehydrogenase P795_13925 ENOG4105GKE subunit e P795_13945 ENOG4105BZU Histidine kinase P795_1395 ENOG4105CJN penicillin-binding protein P795_13955 ENOG4105E0F Histidine kinase P795_13960 ENOG4107EXC regulatoR P795_13970 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) P795_13980 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) P795_1400 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) P795_14040 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) P795_14045 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) P795_1405 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) P795_14080 ENOG4106P55 Transcriptional regulator P795_14095 ENOG4106P55 Transcriptional regulator P795_14100 ENOG4107EFR Flavocytochrome c P795_14105 ENOG41079YP Citrate utilization protein b P795_14110 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F P795_14115 ENOG4107RGD Major Facilitator superfamily P795_14120 ENOG4107RGD Major Facilitator superfamily P795_14125 ENOG4105C1G acyl-Coa dehydrogenase P795_14130 ENOG4105ETT transcriptional Regulator, LysR family P795_14145 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) P795_14150 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) P795_14155 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) P795_14175 ENOG4105E3B Multicopper oxidase P795_14185 ENOG4108HCJ Hydrolase P795_14190 ENOG4105DJV ribulose-phosphate 3-epimerase P795_1420 ENOG4105DHI Methyltransferase P795_14215 ENOG41072GX Peptidase M22 Glycoprotease P795_14220 ENOG4108Z0R Transferase P795_1425 ENOG4108JQC penicillin-binding protein 1A P795_14265 ENOG4105CRQ synthase (Component I) P795_14275 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) P795_14280 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) P795_14285 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) P795_14330 ENOG4105K56 Transcriptional regulator P795_14335 ENOG4108ZHJ Organic hydroperoxide resistance protein P795_14340 ENOG4107QHF type ii secretion system protein e P795_14360 ENOG4105C2M dna polymerase I P795_14365 ENOG4108VIA integral membrane protein P795_14370 ENOG4105II7 pyrroline-5-carboxylate reductase P795_14375 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) P795_14385 ENOG4105C9X ppx gppa phosphatase P795_14395 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) P795_14410 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) P795_14435 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) P795_14450 ENOG4105W39 Membrane P795_14455 ENOG4105CYM Glutathione S-transferase P795_14470 ENOG4105CEY Amp-dependent synthetase and ligase P795_14475 ENOG4105N42 UPF0307 protein P795_14480 ENOG41080Z8 PHOSPHOCARRIER protein P795_1450 ENOG4105E4G Type IV pilus P795_14500 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase P795_14505 ENOG4105DJ0 Poly(A) Polymerase P795_14510 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein P795_14515 ENOG4105DXN mazG family P795_14525 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) P795_14540 ENOG4105C6T cysteine synthase P795_14545 ENOG4105BZU Histidine kinase P795_14550 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase P795_14555 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase P795_14560 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) P795_14575 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) P795_14580 ENOG4105W8H transhydrogenase (subunit alpha P795_14585 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) P795_14590 ENOG4106UX7 integral membrane protein P795_14605 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) P795_14615 ENOG4107RSM transcriptional regulator P795_14620 ENOG4105CUZ uba thif-type nad fad binding protein P795_14625 ENOG4107QM5 aconitate hydratase P795_14630 ENOG4105F8V Hydrolase, tatD family P795_14645 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) P795_14665 ENOG4105BZU Histidine kinase P795_14675 ENOG4108ZP8 Acetolactate synthase small subunit P795_14680 ENOG4105C7K acetolactate synthase P795_1470 ENOG4105CBC glutamate synthase P795_14705 ENOG4105DJY efflux transporter, rnd family, mfp subunit P795_14710 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) P795_14715 ENOG4105ENJ RND efflux system, outer membrane lipoprotein P795_14720 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH P795_14730 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) P795_14735 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) P795_14745 ENOG4105VW4 glutaredoxin 3 P795_1475 ENOG4105BZ8 glutamate synthase P795_14765 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) P795_14785 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) P795_14805 ENOG4105WVQ Fe-S assembly protein IscX P795_14820 ENOG4105CN1 protease P795_14835 ENOG4106HB6 Alpha beta hydrolase P795_14845 ENOG4105C26 Dehydrogenase P795_1485 ENOG4108V0P LemA family P795_14850 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family P795_14855 ENOG4105C6Z Gluconate P795_14860 ENOG4108UHU Aldolase P795_14865 ENOG4105C01 Dihydroxy-acid dehydratase P795_14875 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) P795_14880 ENOG4108DNC Involved in acetate metabolism (By similarity) P795_14885 ENOG4107GFK fumarate P795_1490 ENOG4105HA9 of methanol dehydrogenase type P795_14905 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) P795_14915 ENOG4108ESX Receptor P795_14925 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) P795_14935 ENOG4105DWV Homoserine O-trans-acetylase P795_1500 ENOG4105X0D Fimbrial protein P795_15035 ENOG4105CIY formyltetrahydrofolate deformylase P795_15045 ENOG4107RGH Aldehyde dehydrogenase P795_15050 ENOG4105KDC 50s ribosomal protein l28 P795_15055 ENOG4105W0E 50S ribosomal protein L33 P795_15060 ENOG4105CKD glutathione-regulated potassium-efflux system protein P795_15080 ENOG4105VFU Rna-binding protein P795_15085 ENOG4105C4R Atp-dependent dna helicase P795_15100 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) P795_15110 ENOG4105KVH Transcriptional regulator P795_15120 ENOG41069P5 Protein slyX homolog P795_15125 ENOG4105C5H ABC transporter P795_15130 ENOG4105N14 lysine exporter protein LysE YggA P795_15135 ENOG4105D1S lipid A biosynthesis P795_15145 ENOG4105CK2 sodium dicarboxylate symporter P795_1515 ENOG4108YSG O-Antigen polymerase P795_1520 ENOG4108UQY Iron-storage protein P795_15200 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) P795_15225 ENOG4105DUM transcriptional regulator, lysR family P795_15255 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase P795_15270 ENOG4108W5M transcriptional regulator P795_15285 ENOG4105D29 Helix-turn-helix type 11 domain protein P795_15290 ENOG4107XGZ Hydrolase P795_15295 ENOG4105EI2 Pseudouridine synthase P795_1530 ENOG4105KME endoribonuclease L-psp P795_15300 ENOG4105C03 ribonuclease P795_15310 ENOG4105CBN LysR family transcriptional regulator P795_15315 ENOG4105EMU Dehydrogenase P795_15320 ENOG4105CSA Coproporphyrinogen iii oxidase P795_15330 ENOG4107QI1 Mate efflux family protein P795_15340 ENOG4107T8P acyl-Coa dehydrogenase P795_1535 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) P795_15370 ENOG4105BZ8 glutamate synthase P795_15380 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) P795_15385 ENOG4105C5X domain protein P795_15400 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) P795_15410 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase P795_15420 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) P795_15425 ENOG4108JU5 Magnesium and cobalt efflux protein P795_15430 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) P795_15435 ENOG4108Z7R Chaperone CsaA P795_15445 ENOG4108VAU general secretion pathway protein G P795_1545 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) P795_15450 ENOG4105D7Q type ii secretion system P795_15455 ENOG4105C25 Primosomal protein n' P795_15460 ENOG4105CKD glutathione-regulated potassium-efflux system protein P795_15465 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) P795_15475 ENOG4105DVC DnaJ domain protein P795_15480 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) P795_15485 ENOG4107QUT magnesium and cobalt transport protein CorA P795_15505 ENOG4107QYX exodeoxyribonuclease v alpha P795_15510 ENOG4107QKA exodeoxyribonuclease V beta P795_15515 ENOG4105DSY exodeoxyribonuclease V, gamma P795_15525 ENOG4105CSR polyphosphate kinase 2 P795_15535 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) P795_15555 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase P795_15570 ENOG4105D65 subunit l P795_15575 ENOG4108ZE9 Monovalent cation H antiporter subunit C P795_15580 ENOG4107R4Z monovalent cation h antiporter subunit d P795_15585 ENOG4105SC1 monovalent cation H antiporter subunit E P795_15590 ENOG4105W4C monovalent cation H antiporter subunit F P795_15595 ENOG4105KJM monovalent cation h antiporter subunit g P795_15610 ENOG4105CHV Transcription elongation factor NusA P795_15620 ENOG4107EJC Preprotein translocase subunit SecG P795_15630 ENOG4107QHF type ii secretion system protein e P795_15645 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) P795_15655 ENOG4105C2N RNA methyltransferase TrmH family group 3 P795_15670 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) P795_15680 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) P795_15710 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) P795_15715 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase P795_15770 ENOG4105KV4 Transcriptional regulator P795_15780 ENOG4107ZXU DSBA oxidoreductase P795_15795 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) P795_15810 ENOG4105D3Y Na H antiporter P795_15815 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) P795_15865 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) P795_15870 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) P795_15875 ENOG4105PM1 preprotein translocase subunit SecE P795_15890 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) P795_15895 ENOG4105TV9 FHA Domain-Containing protein P795_15900 ENOG4105GVR general secretion pathway protein D P795_15915 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS P795_15940 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) P795_15945 ENOG4108NEV two component transcriptional regulator, LytTR family P795_1595 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) P795_15950 ENOG4108HRK Histidine kinase P795_15965 ENOG4108UTW Plays a role in the regulation of phosphate uptake P795_15970 ENOG4105DFG type I secretion outer membrane protein P795_15975 ENOG4108RNG Permease of the drug metabolite transporter P795_16000 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) P795_16005 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters P795_16010 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) P795_16015 ENOG4105CNI cell division protein FtsW P795_16030 ENOG4105CE1 Ferrous iron transport protein b P795_16040 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) P795_16045 ENOG4105T95 Thiol disulfide interChange protein P795_16050 ENOG4105D6E homoserine dehydrogenase P795_16060 ENOG41061WM D-Alanyl-D-Alanine P795_16070 ENOG4107TUY Histidine kinase P795_16075 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family P795_16080 ENOG4105CN1 protease P795_16085 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) P795_16090 ENOG4108K5H permease YjgP YjgQ family protein P795_1610 ENOG4107IFA Lipase (EC 3.1.1.3) P795_16130 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) P795_16140 ENOG4105BZU Histidine kinase P795_1615 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) P795_16155 ENOG4105C0P Mg chelatase subunit ChlI P795_16160 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family P795_16170 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) P795_16185 ENOG4105EPF Outer membrane porin P795_16190 ENOG4105F0N pyrophosphate phospho-hydrolase P795_1620 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) P795_16205 ENOG4105CEY Amp-dependent synthetase and ligase P795_16210 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) P795_16215 ENOG41079KZ Major Facilitator Superfamily P795_16220 ENOG4105EN6 Membrane P795_16225 ENOG4105K5B UPF0225 protein P795_16230 ENOG4105EE5 Membrane protein terC P795_16235 ENOG4108URH decarboxylase P795_16240 ENOG4105C0R drug resistance transporter emrb qaca subfamily P795_16250 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) P795_16265 ENOG4105CCT upf0313 protein P795_16285 ENOG4105CS1 NAD(P)H quinone oxidoreductase P795_16295 ENOG4105C6T cysteine synthase P795_16305 ENOG4105Y7M Transcriptional regulator, TetR family P795_16340 ENOG4105C79 DNA protecting protein DprA P795_16355 ENOG4108IND Tetr family transcriptional regulator P795_16360 ENOG4107RTG Major Facilitator superfamily P795_16370 ENOG4108V06 Glutathione peroxidase P795_16380 ENOG41090VV Protein of unknown function (DUF2846) P795_16415 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) P795_16440 ENOG4105FDK ABC transporter P795_16445 ENOG4105FAV ABC, transporter P795_1645 ENOG4108JQ1 Dehydrogenase P795_16455 ENOG4105EZR dyp-type peroxidase family protein P795_16465 ENOG4107R1I NAD-dependent malic enzyme P795_16490 ENOG4105EUB pirin domain protein P795_1650 ENOG4105CQB FAD linked oxidase domain protein P795_16510 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) P795_16515 ENOG4106MP8 UPF0754 membrane protein P795_16520 ENOG4108VBZ doxx family P795_16525 ENOG4105DQR SNARE associated Golgi P795_16540 ENOG4107QJE Chromosome Partitioning Protein P795_16550 ENOG4107PSF BolA-like protein P795_16585 ENOG4105C1G acyl-Coa dehydrogenase P795_16590 ENOG4107RCI amp-dependent synthetase and ligase P795_1660 ENOG4105VRH Antibiotic biosynthesis monooxygenase P795_16610 ENOG4105CSH Transporter P795_16615 ENOG4105E39 Enoyl-CoA hydratase P795_16620 ENOG4105E39 Enoyl-CoA hydratase P795_16625 ENOG4105C1G acyl-Coa dehydrogenase P795_16635 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase P795_16640 ENOG4105C26 Dehydrogenase P795_1665 ENOG4105NF4 modulator of drug activity P795_16650 ENOG4105C85 amino acid P795_16655 ENOG4105C85 amino acid P795_16660 ENOG4105M4H endoribonuclease L-psp P795_16675 ENOG4105EW9 transcriptional regulator AsnC family P795_16700 ENOG4105D3G Pseudouridine synthase P795_16720 ENOG4105TVB Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) P795_16735 ENOG4105CIS alcohol dehydrogenase P795_1675 ENOG4107QF7 multi-drug P795_1680 ENOG4105EM2 membrane P795_16830 ENOG4108I0Z Aconitate hydratase P795_16835 ENOG4105BZN citrate synthase P795_16840 ENOG4105CR4 methylisocitrate lyase P795_16845 ENOG4105DRR Transcriptional regulator, GntR family P795_1685 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) P795_16850 ENOG4105CGF Aromatic amino acid aminotransferase P795_16855 ENOG4105CXG d-lactate dehydrogenase P795_16865 ENOG41073TP transcriptional regulator P795_16870 ENOG4105DAA L-lactate P795_16875 ENOG4107QKV phosphomannomutase P795_16890 ENOG4105C6Y Udp-glucose 6-dehydrogenase P795_16895 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase P795_1690 ENOG4105IPI Membrane P795_16900 ENOG4105D3Q Sugar transferase P795_16910 ENOG4105H63 Glycosyl transferase, family 2 P795_16920 ENOG4108TJN glycosyl transferase group 1 P795_16925 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase P795_16930 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) P795_16935 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase P795_16940 ENOG4105C1B dTDP-glucose 4-6-dehydratase P795_16945 ENOG4105C6Y Udp-glucose 6-dehydrogenase P795_16965 ENOG4107QQG Dehydrogenase P795_16970 ENOG4105DAY polysaccharide export protein P795_16980 ENOG4105D75 Capsular exopolysaccharide family P795_16985 ENOG4108V1T peptidylprolyl cis-trans isomerase P795_16990 ENOG4108V1T peptidylprolyl cis-trans isomerase P795_16995 ENOG4105CJR Integral membrane protein (MviN P795_17000 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase P795_17005 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase P795_17015 ENOG4105HSS phospholipase C P795_17045 ENOG41062JF Transcriptional regulator P795_17060 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) P795_17065 ENOG4105UBK short-chain dehydrogenase reductase P795_17080 ENOG4107QZM n-acetylglutamate synthase P795_17085 ENOG4105GVF (ABC) transporter P795_17090 ENOG4105GVF (ABC) transporter P795_17095 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) P795_17100 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component P795_17105 ENOG4108VM9 ABC, transporter P795_17110 ENOG4108R86 Transcriptional regulator P795_17115 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) P795_17125 ENOG4105DTN riboflavin biosynthesis protein ribF P795_17130 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) P795_17140 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase P795_17160 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) P795_17215 ENOG4105CVE Lytic murein transglycosylase P795_17220 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit P795_17225 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) P795_17235 ENOG4105DFU Cell wall formation (By similarity) P795_17245 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase P795_1725 ENOG4108IQI permease P795_17250 ENOG4105DU1 integral membrane protein, terc P795_17260 ENOG4106032 Glutathionylspermidine synthase P795_17270 ENOG4107QUY Guanine deaminase P795_17280 ENOG4108UGV hypoxanthine phosphoribosyltransferase P795_17290 ENOG4105T95 Thiol disulfide interChange protein P795_17295 ENOG4105PGM cation diffusion facilitator family transporter P795_17310 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins P795_17325 ENOG4105VG0 50S ribosomal protein l34 P795_1735 ENOG4105D82 Glutamate dehydrogenase P795_1740 ENOG4105C8Y Acetylornithine aminotransferase P795_1750 ENOG4105C26 Dehydrogenase P795_1775 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin P795_17895 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) P795_1790 ENOG4105EGI Transcriptional regulator P795_17915 ENOG4108JA2 transcriptioN-repair coupling factor P795_17930 ENOG4106I9N Immunoglobulin G binding protein A P795_18045 ENOG4107RZZ dna polymerase iii epsilon subunit P795_18070 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) P795_18130 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) P795_18135 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) P795_18200 ENOG4105C0B DNA polymerase III (alpha subunit) P795_18210 ENOG4106J5W DNA polymerase III (alpha subunit) P795_18215 ENOG4105C0B DNA polymerase III (alpha subunit) P795_18250 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) P795_18275 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) P795_18310 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) P795_1835 ENOG4105W87 Cbs domain P795_1840 ENOG41067S9 phage shock protein C, PspC P795_1850 ENOG4105CSU acyl-Coa dehydrogenase P795_1865 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) P795_1880 ENOG4105ECY inositol monophosphatase P795_1885 ENOG4105C1J atp-dependent rna helicase P795_1900 ENOG4105DHJ ABC, transporter P795_1905 ENOG4105CY3 ABC transporter, permease P795_1915 ENOG4105E3I toluene tolerance P795_1925 ENOG4105D7N magnesium and cobalt transport protein CorA P795_1930 ENOG4108URH decarboxylase P795_1940 ENOG4105MJ2 Competence protein P795_1945 ENOG4105CB5 ATP-dependent DNA helicase recG P795_1965 ENOG4105C29 acyl-CoA thioesterase P795_1970 ENOG4105CK2 sodium dicarboxylate symporter P795_1985 ENOG4105KPV Transcriptional regulator P795_1995 ENOG4105D7A ATP-binding protein P795_2000 ENOG4105C28 cystathionine P795_2005 ENOG41089BK Glutamine amido-transferase P795_2115 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) P795_2120 ENOG41067V7 50S ribosomal protein L36 P795_2130 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) P795_2155 ENOG4105C1G acyl-Coa dehydrogenase P795_2195 ENOG4105VKU nucleicacid-binding protein P795_2200 ENOG4105DGW oligopeptidase A P795_2205 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) P795_2230 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase P795_2235 ENOG4108K2B transcriptional regulator P795_2245 ENOG4107S2Z UPF0761 membrane protein P795_2250 ENOG4105CS1 NAD(P)H quinone oxidoreductase P795_2280 ENOG4105C9A Phoh family P795_2290 ENOG4105E4C Lytic transglycosylase catalytic P795_2320 ENOG4105D6S protein involved in catabolism of external DNA P795_2325 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase P795_2345 ENOG4105C1G acyl-Coa dehydrogenase P795_2350 ENOG4108RZE Tetr family transcriptional regulator P795_2365 ENOG4107QX3 carboxylase P795_2370 ENOG4105C1G acyl-Coa dehydrogenase P795_2390 ENOG4105KB2 stringent starvation protein b P795_2395 ENOG4107MKT Stringent starvation protein a P795_2400 ENOG4108UJD 30S ribosomal protein S9 P795_2410 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) P795_2415 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) P795_2420 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) P795_2440 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) P795_2450 ENOG4107RZC phospholipase d P795_2460 ENOG4105UYK outer membrane protein a P795_2465 ENOG4108KHX Diguanylate cyclase P795_2475 ENOG4107QN2 dihydrolipoyl dehydrogenase P795_2485 ENOG4107QPB Beta-lactamase domain protein P795_2490 ENOG4107U2T alpha beta P795_2500 ENOG4105NAU thioesterase Superfamily protein P795_2530 ENOG4105K9H YciI-like protein P795_2540 ENOG4105DB7 PHP domain protein P795_2545 ENOG4105FFC UPF0187 protein P795_2555 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase P795_2560 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) P795_2565 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) P795_2570 ENOG4105VIE preprotein translocase, subunit YajC P795_2600 ENOG4105BZU Histidine kinase P795_2605 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) P795_2610 ENOG4105CM2 brancheD-chain amino acid aminotransferase P795_2625 ENOG4107TYR Glycosyl Transferase P795_2635 ENOG4105C1B dTDP-glucose 4-6-dehydratase P795_2640 ENOG4105C1B dTDP-glucose 4-6-dehydratase P795_2660 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) P795_2700 ENOG4105UGU tonB-dependent Receptor P795_2720 ENOG4108VY7 phosphate-starvation-inducible protein PsiE P795_2725 ENOG4105CSU acyl-Coa dehydrogenase P795_2730 ENOG4105CSU acyl-Coa dehydrogenase P795_2740 ENOG4105EB3 Histidine kinase P795_2745 ENOG4105E3W Two component transcriptional regulator (Winged helix family P795_2750 ENOG4105CNG UPF0061 protein P795_2770 ENOG4108WBT adenosyltransferase P795_2785 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) P795_2820 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase P795_2840 ENOG4105D3R alkyl hydroperoxide reductase P795_2855 ENOG4105CSH Transporter P795_2860 ENOG4108UT2 hemolysin iii P795_2890 ENOG4105CHU acetyl-coa acetyltransferase P795_2895 ENOG4108R6W Transcriptional regulator, ARAC family P795_2905 ENOG4105TW1 Carbohydrate-selective porin OprB P795_2910 ENOG4105DZG Dehydrogenase P795_2915 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) P795_2925 ENOG410814C multidrug resistance protein P795_2935 ENOG4105CHU acetyl-coa acetyltransferase P795_2945 ENOG4108WHA ompa motb domain protein P795_2955 ENOG4105E0Y RtcB Protein P795_2960 ENOG4108IQI permease P795_2965 ENOG4108IQI permease P795_2975 ENOG4105C2W permease P795_2995 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) P795_3005 ENOG4108VX5 3-methyladenine DNA glycosylase P795_3010 ENOG4105CHB tonB-dependent Receptor P795_3015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase P795_3030 ENOG4105T95 Thiol disulfide interChange protein P795_3035 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) P795_3045 ENOG4105K78 MarR family Transcriptional regulator P795_3050 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA P795_3055 ENOG4105KWI UPF0339 protein P795_3080 ENOG4108UNF response regulator P795_3085 ENOG4105M3Z response regulator P795_3090 ENOG4108ZGA chew protein P795_3095 ENOG4105C8Q Methyl-accepting chemotaxis P795_3100 ENOG4105CBS Chea signal transduction histidine kinase P795_3115 ENOG4106HKS Entericidin EcnA/B family P795_3125 ENOG4105WD1 Membrane P795_3130 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein P795_3140 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) P795_3150 ENOG4105EM2 membrane P795_3155 ENOG4105C2C drug resistance transporter, Bcr CflA P795_3175 ENOG4105BZG amino acid carrier protein P795_3180 ENOG4105D78 K07001 NTE family protein P795_3185 ENOG4105C7B Threonine dehydratase P795_3195 ENOG4105C9K Endothelin-converting enzyme 1 P795_3220 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) P795_3230 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) P795_3235 ENOG4105DFF Rod shape-determining protein mreb P795_3240 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) P795_3245 ENOG4105VQ7 Rod shape-determining protein MreD P795_3250 ENOG4108Z03 MAF-like protein P795_3255 ENOG4105C03 ribonuclease P795_3265 ENOG4105D8T Acyltransferase P795_3275 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein P795_3285 ENOG4108X0B nad(p)h dehydrogenase (quinone) P795_3310 ENOG4105CF7 AraC family transcriptional regulator P795_3325 ENOG4105C85 amino acid P795_3330 ENOG4105C7F AcnD-accessory protein PrpF P795_3335 ENOG4105CTB Polyprenyl synthetase P795_3340 ENOG4105MSB protein, conserved in bacteria P795_3355 ENOG4105D78 K07001 NTE family protein P795_3380 ENOG4105DIJ Phosphoethanolamine transferase P795_3385 ENOG4105XJC Two component transcriptional regulator (Winged helix family P795_3390 ENOG4105DHQ Histidine kinase P795_3405 ENOG4108M0I Transcriptional regulator P795_3425 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) P795_3445 ENOG4105K8R UPF0145 protein P795_3450 ENOG4105K8R UPF0145 protein P795_3455 ENOG4105ENJ RND efflux system, outer membrane lipoprotein P795_3460 ENOG4105BZS acriflavin resistance protein P795_3465 ENOG4105C1P efflux transporter, rnd family, mfp subunit P795_3470 ENOG410841Q phosphoesterase PA-phosphatase related protein P795_3500 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) P795_3515 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) P795_3520 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) P795_3525 ENOG4105KVH Transcriptional regulator P795_3535 ENOG4105CUB amino acid P795_3550 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) P795_3555 ENOG41084BA UPF0250 protein P795_3560 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) P795_3590 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit P795_3595 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein P795_3605 ENOG4105E33 succinate dehydrogenase P795_3610 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 P795_3615 ENOG4105C7S Dehydrogenase P795_3620 ENOG4107QN2 dihydrolipoyl dehydrogenase P795_3630 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha P795_3640 ENOG4105CKW Inner membrane protein yedI P795_3645 ENOG4105CGZ zinc metallopeptidase P795_3650 ENOG4105EEQ Na H antiporter P795_3670 ENOG4105PNM synthesis protein P795_3685 ENOG41080TK Universal stress protein P795_3700 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain P795_3705 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain P795_3720 ENOG4105HBR Rna-binding protein P795_3730 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) P795_3735 ENOG4105EEI dihydropteroate synthase P795_3770 ENOG4105CSH Transporter P795_3775 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) P795_3780 ENOG4105C6V Glycerol-3-phosphate dehydrogenase P795_3795 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) P795_3810 ENOG41080IJ Diacylglycerol kinase P795_3820 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase P795_3825 ENOG4105BZS acriflavin resistance protein P795_3840 ENOG4105E4C Lytic transglycosylase catalytic P795_3860 ENOG4108RRZ Transcription elongation factor GreB P795_3870 ENOG4105CEY Amp-dependent synthetase and ligase P795_3915 ENOG4105BZW Glycerate kinase P795_3920 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit P795_3925 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) P795_3940 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) P795_3950 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) P795_3955 ENOG4105C85 amino acid P795_3965 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) P795_3975 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) P795_3980 ENOG4105N14 lysine exporter protein LysE YggA P795_3985 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) P795_3990 ENOG4105BZJ Electron transfer flavoprotein P795_3995 ENOG4105C10 Electron transfer flavoprotein P795_4000 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) P795_4040 ENOG4107KET secretion protein, HlyD family P795_4070 ENOG4105D60 lipoprotein releasing system transmembrane protein P795_4075 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) P795_4080 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 P795_4090 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) P795_4095 ENOG4107R6F Alpha Beta Hydrolase Fold protein P795_4100 ENOG4108V3E phosphoribosylglycinamide formyltransferase P795_4110 ENOG4105C02 permease P795_4160 ENOG4105KCK Peptidoglycan-associated lipoprotein P795_4165 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) P795_4175 ENOG4105M8F Biopolymer transport protein exbD tolR P795_4180 ENOG4105E02 MotA TolQ exbB proton channel P795_4185 ENOG4107YD3 Thioesterase P795_4190 ENOG4105CH2 amidohydrolase P795_4210 ENOG4108ETH Formylglycinamide ribotide synthetase P795_4215 ENOG4105C2C drug resistance transporter, Bcr CflA P795_4225 ENOG4105EGD dinuclear metal center protein, YbgI family P795_4230 ENOG4108UKI Enoyl-CoA hydratase P795_4245 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen P795_4260 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) P795_4265 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) P795_4280 ENOG4107R11 Transcriptional regulator P795_4285 ENOG4108IJ6 ABC transporter P795_4295 ENOG4108I5D sulfate abc transporter P795_4305 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein P795_4310 ENOG4105YAZ 4-amino-4-deoxychorismate lyase P795_4315 ENOG4105HHA aminodeoxychorismate lyase P795_4330 ENOG4108IYU L-aspartate oxidase P795_4335 ENOG4105C0H protease P795_4350 ENOG4105C3F Signal peptidase i P795_4365 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) P795_4375 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) P795_4380 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) P795_4385 ENOG4105EMU Dehydrogenase P795_4415 ENOG4105BZU Histidine kinase P795_4425 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) P795_4435 ENOG4105DTR rard protein P795_4470 ENOG4107QS8 (LipO)protein P795_4475 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) P795_4480 ENOG4105EA8 2-Nitropropane dioxygenase P795_4510 ENOG4107R8N Glycosyl transferase, family 2 P795_4525 ENOG4105CVP deoxyribo-dipyrimidine photolyase P795_4530 ENOG4108YZY peptidylprolyl cis-trans isomerase P795_4535 ENOG4105CEP NADH dehydrogenase P795_4540 ENOG4105DZ1 carboxypeptidase P795_4550 ENOG4105E9K Isocitrate dehydrogenase P795_4555 ENOG4108R99 pseudouridine synthase P795_4585 ENOG4105EGI Transcriptional regulator P795_4590 ENOG4108ETY sodium dicarboxylate symporter P795_4595 ENOG4105JAB phenazine biosynthesis protein, phzf family P795_4625 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) P795_4640 ENOG4105D3G Pseudouridine synthase P795_4645 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) P795_4660 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) P795_4685 ENOG4108JPW Aminotransferase P795_4690 ENOG4105DY8 decarboxylase P795_4700 ENOG4105F7P transcriptional regulator AsnC family P795_4705 ENOG4107RA9 decarboxylase P795_4710 ENOG4105C85 amino acid P795_4715 ENOG4105CVA phosphate P795_4720 ENOG4105C8U phosphate abc transporter P795_4730 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) P795_4735 ENOG4105ERU peptidase P795_4750 ENOG4107QTF adenylosuccinate lyase P795_4770 ENOG4108Z0R Transferase P795_4775 ENOG4105DZ1 carboxypeptidase P795_4795 ENOG4108K5P (LipO)protein P795_4800 ENOG4105EJC lysr family transcriptional regulator P795_4805 ENOG4105DAN ATP-dependent protease P795_4820 ENOG4105DHU Bile acid P795_4830 ENOG41066DG (EAL) domain protein P795_4840 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein P795_4850 ENOG4105D22 carbon starvation protein P795_4855 ENOG4105VCD cytoplasmic protein P795_4890 ENOG4105CHJ isochorismatase hydrolase P795_4895 ENOG4105CR8 Transcriptional regulator P795_4905 ENOG4107RN6 Monooxygenase P795_4910 ENOG4105D74 hydrolase P795_4950 ENOG4105C2I pirin domain protein P795_4960 ENOG4105WWK YheO domain protein P795_4975 ENOG4105CEY Amp-dependent synthetase and ligase P795_4995 ENOG4108IPW abc transporter atp-binding protein P795_5015 ENOG4105C0W non-ribosomal peptide synthetase P795_5020 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase P795_5025 ENOG4105WQI isochorismatase P795_5040 ENOG4105BZ1 (ABC) transporter P795_5045 ENOG4108JJ7 ABC transporter P795_5060 ENOG4105E4F Isochorismate synthase P795_5075 ENOG4105NX3 Membrane P795_5095 ENOG4105EUJ GTP cyclohydrolase i P795_5105 ENOG4105C7W Xanthine dehydrogenase P795_5115 ENOG4108DG9 Smr protein MutS2 P795_5135 ENOG4105CD8 aminopeptidase N P795_5140 ENOG4105DDQ anthranilate synthase P795_5150 ENOG4105DUX Transporter P795_5155 ENOG4105C5F glutamine synthetase P795_5165 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) P795_5185 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) P795_5190 ENOG4107QNR UPF0135 protein P795_5195 ENOG4105C0H protease P795_5205 ENOG4105C6K Malic enzyme P795_5210 ENOG4105BZU Histidine kinase P795_5215 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) P795_5220 ENOG4105SYT Methylenetetrahydrofolate reductase P795_5225 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) P795_5240 ENOG4107QPN acyl-Coa dehydrogenase P795_5245 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) P795_5250 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) P795_5265 ENOG4107RNU major facilitator superfamily MFS_1 P795_5275 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) P795_5280 ENOG4105CE9 30S ribosomal protein S2 P795_5320 ENOG4105CVE Lytic murein transglycosylase P795_5325 ENOG4105CNI cell division protein FtsW P795_5340 ENOG4105E3A (ABC) transporter P795_5345 ENOG4105DA5 (ABC) transporter P795_5370 ENOG4105ENJ RND efflux system, outer membrane lipoprotein P795_5380 ENOG4105ENT Efflux transporter rnd family, mfp subunit P795_5395 ENOG4105E89 ABC transporter P795_5400 ENOG4105DSP amino acid AbC transporter P795_5405 ENOG4106YG3 ABC transporter P795_5410 ENOG4108JEH abc transporter atp-binding protein P795_5420 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding P795_5425 ENOG4105CFP Peptidase U32 P795_5430 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family P795_5435 ENOG4105JAB phenazine biosynthesis protein, phzf family P795_5440 ENOG4105DP0 ferredoxin-NADP reductase P795_5445 ENOG4108R96 Methyltransferase, YaeB family P795_5460 ENOG4107QHF type ii secretion system protein e P795_5470 ENOG4105XJC Two component transcriptional regulator (Winged helix family P795_5475 ENOG4105DHQ Histidine kinase P795_5485 ENOG4105M6F mutator MutT protein P795_5495 ENOG4105BZ4 penicillin-binding protein P795_5500 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) P795_5505 ENOG4105VUT cytoplasmic protein P795_5515 ENOG4105CK2 sodium dicarboxylate symporter P795_5520 ENOG4105C1G acyl-Coa dehydrogenase P795_5530 ENOG4105CQC Prephenate dehydratase P795_5535 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase P795_5545 ENOG4105CIN aminoacyl-histidine dipeptidase P795_5565 ENOG4105E0Y RtcB Protein P795_5570 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) P795_5575 ENOG4105CYB regulatoR P795_5605 ENOG4105M08 Membrane P795_5610 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) P795_5620 ENOG4105VEQ Cold shock protein P795_5625 ENOG4105C1J atp-dependent rna helicase P795_5635 ENOG41069NU Nitroreductase P795_5670 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase P795_5685 ENOG4105C5I Dehydrogenase P795_5690 ENOG4105ERG peptidase m48, ste24p P795_5695 ENOG4105KTH gatB Yqey P795_5700 ENOG4105VCC 30S ribosomal protein S21 P795_5725 ENOG4105D9P serine threonine protein kinase P795_5730 ENOG4105D5K Hemolysin activator protein P795_5735 ENOG4105CKT filamentous hemagglutinin P795_5735 ENOG4105CKT filamentous hemagglutinin P795_5760 ENOG4105EVZ LysR family transcriptional regulator P795_5765 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) P795_5770 ENOG4105C26 Dehydrogenase P795_5805 ENOG4105H4F exported protein P795_5835 ENOG4105D6U Sodium Glutamate Symporter P795_5845 ENOG4105JXH GntR family transcriptional regulator P795_5895 ENOG4105CSH Transporter P795_5930 ENOG4105F1S paraquat-inducible protein a P795_5935 ENOG4105DY2 Paraquat-inducible protein b P795_5950 ENOG4105C3M thioredoxin reductase P795_5985 ENOG4105CK2 sodium dicarboxylate symporter P795_5995 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) P795_6000 ENOG4108UMI ABC transporter, permease P795_6005 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) P795_6015 ENOG4105C12 Phosphoribosylglycinamide synthetase P795_6020 ENOG4105DC1 bifunctional purine biosynthesis protein purh P795_6025 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) P795_6080 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) P795_6085 ENOG4105CDU Replicative dna helicase P795_6110 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) P795_6115 ENOG4105CCU oxidase (Subunit III) P795_6120 ENOG4105BZ9 Cytochrome C oxidase, subunit I P795_6125 ENOG4105E2S oxidase) subunit II P795_6150 ENOG4107BJW polysaccharide deacetylase P795_6155 ENOG4105CND Glycosyl transferase, family 2 P795_6160 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD P795_6170 ENOG4105DEN Luciferase family P795_6185 ENOG4105CC0 LysR family Transcriptional regulator P795_6200 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) P795_6215 ENOG4105C1G acyl-Coa dehydrogenase P795_6225 ENOG4108MEJ flavin reductase domain protein P795_6230 ENOG4105D06 uba thif-type nad fad binding protein P795_6250 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) P795_6255 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) P795_6265 ENOG4105C08 Histidine kinase P795_6270 ENOG4105EEX Two component transcriptional regulator (Winged helix family P795_6275 ENOG4105CFQ glutamine synthetase P795_6290 ENOG4107S74 Lysophospholipid transporter LplT P795_6295 ENOG4105CFU surface antigen P795_6310 ENOG4107QIJ Aconitate hydratase 2 P795_6320 ENOG4105EYW Ion transport protein P795_6325 ENOG4105F27 Major Facilitator P795_6340 ENOG4105DZ2 Transcriptional regulator P795_6375 ENOG4105K8N protein family UPF0079, ATPase P795_6380 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) P795_6390 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) P795_6395 ENOG4108TZV Membrane P795_6400 ENOG4108RCM Nitroreductase P795_6410 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) P795_6425 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) P795_6430 ENOG4107FQ9 ethanolamine ammonia-lyase P795_6435 ENOG4105CPD ethanolamine ammonia-lyase P795_6440 ENOG4107R55 ethanolamine transporter P795_6450 ENOG4107RR1 TRANSCRIPTIONal P795_6460 ENOG4105C0A alcohol dehydrogenase P795_6465 ENOG4107QUV Domain protein P795_6490 ENOG4105CD8 aminopeptidase N P795_6505 ENOG4108D1K outer membrane usher protein P795_6520 ENOG4105EMU Dehydrogenase P795_6530 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) P795_6535 ENOG4105EW9 transcriptional regulator AsnC family P795_6545 ENOG4105CAT Cytidine monophosphate kinase P795_6560 ENOG4105R8C Transcriptional regulator P795_6570 ENOG4105CUY Mechanosensitive ion channel P795_6600 ENOG4105CNM Receptor P795_6620 ENOG4105C5H ABC transporter P795_6625 ENOG41081QV Universal stress protein P795_6645 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic P795_6655 ENOG4105DKK Benzoate P795_6660 ENOG4105EW9 transcriptional regulator AsnC family P795_6665 ENOG4108NIW Leucine export protein LeuE P795_6670 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) P795_6675 ENOG4105C5Q Transcriptional regulator P795_6685 ENOG4105CHU acetyl-coa acetyltransferase P795_6690 ENOG4105CHR reductase P795_6715 ENOG4107QMP dna polymerase iii subunits gamma and tau P795_6720 ENOG4105HSS phospholipase C P795_6725 ENOG4105HSS phospholipase C P795_6735 ENOG4105C0A alcohol dehydrogenase P795_6765 ENOG4105CBC glutamate synthase P795_6785 ENOG4105D8G Major Facilitator superfamily P795_6795 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase P795_6800 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein P795_6820 ENOG4105CK6 Two component transcriptional regulator (Winged helix family P795_6830 ENOG4107QZF nitrite reductase NADPH large subunit P795_6835 ENOG4108IFG nitrite reductase, (NAD(P)H) P795_6870 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) P795_6875 ENOG4105CVM Molybdenum cofactor synthesis domain protein P795_6885 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family P795_6890 ENOG4105T38 integral membrane protein P795_6910 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) P795_6915 ENOG4105CMR udp-glucose 4-epimerase P795_6970 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family P795_6975 ENOG4105CUX Signal transduction histidine kinase P795_6995 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) P795_7000 ENOG4105KNE Phosphatidate cytidylyltransferase P795_7010 ENOG4105DZP Membrane-associated zinc metalloprotease P795_7015 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane P795_7035 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) P795_7045 ENOG4105Y3E Modulates RecA activity (By similarity) P795_7055 ENOG4105VEJ Heat shock protein P795_7060 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 P795_7085 ENOG4105F7P transcriptional regulator AsnC family P795_7095 ENOG4105C85 amino acid P795_7110 ENOG4105CHH sulfate transporter P795_7115 ENOG4108RAV Conserved protein P795_7120 ENOG4105D8V Glucose sorbosone dehydrogenase P795_7130 ENOG4105BZU Histidine kinase P795_7145 ENOG4105DM4 PTS System P795_7150 ENOG4105DE4 1-phosphofructokinase P795_7155 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) P795_7180 ENOG4105CWM branched-chain amino acid transport system II carrier protein P795_7185 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) P795_7190 ENOG4105CC0 LysR family Transcriptional regulator P795_7200 ENOG4105M2J Glutaredoxin P795_7205 ENOG4105C8Y Acetylornithine aminotransferase P795_7210 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) P795_7235 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) P795_7245 ENOG41068P6 UPF0319 protein P795_7260 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii P795_7265 ENOG4105C4M (Ubiquinol oxidase) subunit I P795_7275 ENOG4105PV3 Inner membrane protein yqiJ P795_7290 ENOG4105E0K tonB-dependent siderophore receptor P795_7300 ENOG4105HDD phospholipase P795_7305 ENOG4105CZN Potassium uptake protein P795_7315 ENOG4105C7B Threonine dehydratase P795_7345 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) P795_7350 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit P795_7360 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) P795_7375 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase P795_7420 ENOG4107VMU Membrane P795_7425 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) P795_7435 ENOG4107QP7 CoA-transferase subunit A P795_7440 ENOG4107QP7 CoA-transferase subunit A P795_7445 ENOG4107QNJ CoA-transferase subunit B P795_7450 ENOG4107QNJ CoA-transferase subunit B P795_7455 ENOG4105CHU acetyl-coa acetyltransferase P795_7460 ENOG4105F2Z 3-oxoadipate enol-lactonase P795_7470 ENOG4105C26 Dehydrogenase P795_7480 ENOG4105F11 amine oxidase P795_7500 ENOG4105CHR reductase P795_7510 ENOG4105FUY alpha subunit P795_7530 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) P795_7545 ENOG4105DNH Major Facilitator P795_7570 ENOG4105C1G acyl-Coa dehydrogenase P795_7575 ENOG4108PTX LysR family Transcriptional regulator P795_7580 ENOG4107HP6 Transcriptional regulator P795_7595 ENOG4105MD1 YeeE YedE family protein P795_7610 ENOG4105DZG Dehydrogenase P795_7615 ENOG4105TW1 Carbohydrate-selective porin OprB P795_7620 ENOG4106JPM 3-dehydroshikimate dehydratase P795_7625 ENOG4105FF2 Type I DHQase P795_7630 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha P795_7635 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta P795_7640 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase P795_7645 ENOG4105D2S major facilitator superfamily P795_7650 ENOG4105F2Z 3-oxoadipate enol-lactonase P795_7655 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase P795_7660 ENOG4105CHU acetyl-coa acetyltransferase P795_7665 ENOG4107QNJ CoA-transferase subunit B P795_7670 ENOG4107QP7 CoA-transferase subunit A P795_7680 ENOG4105NN7 muconolactone delta-isomerase P795_7685 ENOG4105DTQ mandelate racemase muconate lactonizing P795_7690 ENOG4108KB2 LysR family Transcriptional regulator P795_7700 ENOG4107EJG GntR family transcriptional regulator P795_7720 ENOG4105CZJ Aldehyde dehydrogenase P795_7750 ENOG4108Z6Z Transcriptional regulator P795_7775 ENOG4107Z3H Transcriptional regulator, TetR family P795_7780 ENOG4108PTX LysR family Transcriptional regulator P795_7785 ENOG41061TZ Short-chain dehydrogenase reductase Sdr P795_7790 ENOG41061TZ Short-chain dehydrogenase reductase Sdr P795_7795 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr P795_7805 ENOG4105CSU acyl-Coa dehydrogenase P795_7815 ENOG4105CEY Amp-dependent synthetase and ligase P795_7835 ENOG4105D5K Hemolysin activator protein P795_7840 ENOG4105CKT filamentous hemagglutinin P795_7870 ENOG4105FDP GntR family transcriptional regulator P795_7885 ENOG4106P55 Transcriptional regulator P795_7910 ENOG4108JQ1 Dehydrogenase P795_7915 ENOG4105JSC dimethylmenaquinone methyltransferase P795_7925 ENOG4105CW7 secretion protein, HlyD family P795_7940 ENOG4107VQW regulatoR P795_7945 ENOG4105CJP fad dependent oxidoreductase P795_7965 ENOG4105CJP fad dependent oxidoreductase P795_7985 ENOG4105C26 Dehydrogenase P795_8000 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) P795_8005 ENOG4105C2C drug resistance transporter, Bcr CflA P795_8015 ENOG4105ERH Fumarylacetoacetate hydrolase P795_8025 ENOG4105C26 Dehydrogenase P795_8030 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase P795_8045 ENOG4105CNV Aldolase P795_8050 ENOG4105C26 Dehydrogenase P795_8055 ENOG4105CSH Transporter P795_8075 ENOG4108V8F Transcriptional regulator, MarR family P795_8080 ENOG4105CZJ Aldehyde dehydrogenase P795_8085 ENOG4105C01 Dihydroxy-acid dehydratase P795_8095 ENOG4105DDW LysR family Transcriptional regulator P795_8100 ENOG4105EXW epimerase dehydratase P795_8110 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase P795_8115 ENOG4105CF7 AraC family transcriptional regulator P795_8130 ENOG4105DQ4 alcohol dehydrogenase P795_8140 ENOG4105EHG Permease protein P795_8145 ENOG4105E0A ABC, transporter P795_8165 ENOG4105C5T Phosphoribosyl pyrophosphate synthase P795_8215 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) P795_8250 ENOG4108BAS reductase P795_8255 ENOG4105EMU Dehydrogenase P795_8265 ENOG4108R6W Transcriptional regulator, ARAC family P795_8270 ENOG4108821 RND type efflux pump P795_8275 ENOG4105E0F Histidine kinase P795_8280 ENOG4105CK6 Two component transcriptional regulator (Winged helix family P795_8285 ENOG4105C1P efflux transporter, rnd family, mfp subunit P795_8290 ENOG4105BZS acriflavin resistance protein P795_8295 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) P795_8310 ENOG4105X0I Fimbrial P795_8360 ENOG4107RZC phospholipase d P795_8380 ENOG4108IGT Dipeptidase P795_8410 ENOG4107T31 5'-nucleotidase P795_8420 ENOG4105WQI isochorismatase P795_8425 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase P795_8430 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) P795_8435 ENOG4105E0C molybdate abc transporter P795_8440 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein P795_8445 ENOG4105F4R Transcriptional regulator mode P795_8450 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit P795_8455 ENOG4108YS2 small subunit P795_8460 ENOG4105F57 Anthranilate dioxygenase reductase P795_8485 ENOG4105CHR reductase P795_8495 ENOG4105D2S major facilitator superfamily P795_8500 ENOG4105D2S major facilitator superfamily P795_8505 ENOG4105CF7 AraC family transcriptional regulator P795_8510 ENOG4105DTD Dehydrogenase P795_8515 ENOG4105CY2 Citrate transporter P795_8525 ENOG4108IND Tetr family transcriptional regulator P795_8550 ENOG4108M0I Transcriptional regulator P795_8565 ENOG4105CRW Short chain fatty acid transporter P795_8570 ENOG4105CHU acetyl-coa acetyltransferase P795_8580 ENOG4107YNJ LysR family Transcriptional regulator P795_8595 ENOG4108IJ0 Aspartate ammonia-lyase P795_8605 ENOG4105CSH Transporter P795_8625 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component P795_8630 ENOG4106FTQ Taurine ABC transporter, periplasmic P795_8645 ENOG4105FDP GntR family transcriptional regulator P795_8655 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) P795_8660 ENOG4105KVH Transcriptional regulator P795_8665 ENOG4105UEI Transcriptional Regulator AraC Family P795_8680 ENOG4108VCT Sulfite exporter TauE/SafE P795_8690 ENOG4107QPB Beta-lactamase domain protein P795_8700 ENOG4105FFC UPF0187 protein P795_8710 ENOG4105CHR reductase P795_8725 ENOG4105CPP Dehydrogenase, E1 component P795_8730 ENOG4107R0V Pyruvate dehydrogenase P795_8735 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) P795_8750 ENOG4105BZU Histidine kinase P795_8760 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) P795_8765 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) P795_8810 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) P795_8825 ENOG4105C28 cystathionine P795_8835 ENOG4105F2W methyltransferase P795_8870 ENOG4105K59 histidine triad (HIT) protein P795_8895 ENOG4107QWP ABC-2 type transporter P795_8900 ENOG4107QWP ABC-2 type transporter P795_8905 ENOG4105CJ1 ABC, transporter P795_8920 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) P795_8925 ENOG4105CNM Receptor P795_8945 ENOG4107TSN permease P795_8950 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) P795_8970 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) P795_8975 ENOG4108YZT Adenosylcobinamide kinase P795_9020 ENOG4105JSC dimethylmenaquinone methyltransferase P795_9030 ENOG4105DJU Siderophore biosynthesis protein P795_9035 ENOG4105DUU IucA IucC family protein P795_9040 ENOG4105C0R drug resistance transporter emrb qaca subfamily P795_9055 ENOG4108Z66 YbaK ebsC protein P795_9070 ENOG4105C1G acyl-Coa dehydrogenase P795_9075 ENOG4105C1G acyl-Coa dehydrogenase P795_9080 ENOG4105EEF Alkane 1-monooxygenase P795_9085 ENOG4105E7U AraC family transcriptional regulator P795_9090 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) P795_9095 ENOG4105K70 DNA-binding protein P795_9110 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family P795_9120 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins P795_9125 ENOG4108Z4V iron-sulfur cluster assembly P795_9140 ENOG4108ZIT Ferredoxin, 2FE-2S P795_9145 ENOG4105F8J Adenylate Guanylate cyclase P795_9155 ENOG4108JA2 transcriptioN-repair coupling factor P795_9175 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) P795_9180 ENOG4105K4T epimerase P795_9195 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase P795_9215 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component P795_9225 ENOG4105DGW oligopeptidase A P795_9260 ENOG4105SG9 biopolymer transport protein, ExbD P795_9265 ENOG4107QP3 malate synthase g P795_9270 ENOG4105D6Z AFG1 family ATPase P795_9280 ENOG4107RN6 Monooxygenase P795_9300 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) P795_9305 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) P795_9320 ENOG4108Z6B deaminase P795_9340 ENOG4108RTD type II secretion system protein K P795_9365 ENOG4105F8V Hydrolase, tatD family P795_9375 ENOG4107QRG dna polymerase iii P795_9385 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) P795_9390 ENOG4105BZ1 (ABC) transporter P795_9395 ENOG4105SG9 biopolymer transport protein, ExbD P795_9405 ENOG4105FA0 parb-like partition protein P795_9410 ENOG4107QJE Chromosome Partitioning Protein P795_9420 ENOG4108S0S Nucleotidyl transferase P795_9425 ENOG4105EHM Aminoglycoside phosphotransferase P795_9430 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) P795_9435 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) P795_9440 ENOG4105D2N Aldolase P795_9460 ENOG4108UHJ MAF-like protein P795_9465 ENOG4105EZE Cupin 4 family protein P795_9475 ENOG41080HT Transcriptional regulator, arsr family P795_9485 ENOG4105XPP Protein of unknown function (DUF1275) P795_9490 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme P795_9495 ENOG4105BZ1 (ABC) transporter P795_9505 ENOG4108ZX5 transcriptional regulator P795_9515 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) P795_9520 ENOG4105CK7 Sodium proline symporter P795_9525 ENOG4105EW9 transcriptional regulator AsnC family P795_9530 ENOG4105C26 Dehydrogenase P795_9535 ENOG4105YGK Pfam:UPF0157 P795_9550 ENOG4108T58 Mg2 transport protein CorA P795_9560 ENOG4108YYC ycei family P795_9570 ENOG4105CV1 Transketolase (EC 2.2.1.1) P795_9600 ENOG4108HWY Beta-lactamase P795_9620 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) P795_9625 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) P795_9645 ENOG4105X0I Fimbrial P795_9650 ENOG4105GQR Chaperone P795_9670 ENOG4108ZX5 transcriptional regulator P795_9685 ENOG4108IPJ Membrane P795_9695 ENOG4105ETS cytosine purines uracil thiamine allantoin P795_9705 ENOG4105CC0 LysR family Transcriptional regulator P795_9720 ENOG41067SE Tetr family transcriptional regulator P795_9735 ENOG4105EW9 transcriptional regulator AsnC family P795_9745 ENOG4105CDA abc transporter atp-binding protein P795_9750 ENOG4105DRP amino acid AbC transporter P795_9755 ENOG4105EAD ABC transporter P795_9770 ENOG4107T8P acyl-Coa dehydrogenase P795_9785 ENOG4105D01 (LipO)protein P795_9790 ENOG4105D01 (LipO)protein P795_9795 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) P795_9800 ENOG4108UMI ABC transporter, permease P795_9805 ENOG4105C3G gtp-binding protein P795_9830 ENOG4108UMN azlc family P795_9835 ENOG4105ZED uncharacterized protein ygaH P795_9865 ENOG4105E7U AraC family transcriptional regulator P795_9870 ENOG4108V06 Glutathione peroxidase P795_9880 ENOG4105CHM Aminotransferase P795_9885 ENOG4105CK2 sodium dicarboxylate symporter P795_9895 ENOG4105C0B DNA polymerase III (alpha subunit) P795_9930 ENOG4108KB2 LysR family Transcriptional regulator P795_9935 ENOG4105D6J arsenicaL-resistance protein P795_9940 ENOG41082YX Transcriptional regulator, arsr family P795_9955 ENOG4105CPN adenine deaminase P795_9965 ENOG4105CBN LysR family transcriptional regulator P795_9975 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease P795_9985 ENOG4105E2B Taurine dioxygenase P795_9990 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component P795_9995 ENOG4108IY8 ABC, transporter