locus-tag	class	description
A4U85_00010	COG0592	DNA-directed DNA polymerase activity
A4U85_00020	COG0187	DNA topoisomerase II activity
A4U85_00030	COG0586	Pfam SNARE associated Golgi protein
A4U85_00035	COG0488	(ABC) transporter
A4U85_00060	COG0596	Alpha beta hydrolase
A4U85_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A4U85_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A4U85_00105	COG0625	glutathione transferase activity
A4U85_00115	COG0733	neurotransmitter:sodium symporter activity
A4U85_00150	COG0583	DNA-binding transcription factor activity
A4U85_00155	COG2233	PERMEase
A4U85_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_00205	COG2814	Major facilitator Superfamily
A4U85_00210	COG0656	L-ascorbic acid biosynthetic process
A4U85_00215	COG0583	DNA-binding transcription factor activity
A4U85_00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4U85_00230	COG1064	alcohol dehydrogenase
A4U85_00235	COG2818	Glycosylase
A4U85_00250	COG1194	a g-specific adenine glycosylase
A4U85_00270	COG2983	Belongs to the UPF0260 family
A4U85_00275	COG2133	pyrroloquinoline quinone binding
A4U85_00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A4U85_00285	COG2116	formate transmembrane transporter activity
A4U85_00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A4U85_00310	COG1335	isochorismatase
A4U85_00315	COG0385	Bile acid
A4U85_00325	COG1683	Conserved Protein
A4U85_00345	COG0625	glutathione transferase activity
A4U85_00355	COG1113	amino acid transport
A4U85_00365	COG0523	cobalamin synthesis protein
A4U85_00375	COG2188	Transcriptional regulator
A4U85_00405	COG0010	Belongs to the arginase family
A4U85_00415	COG0546	phosphoglycolate phosphatase activity
A4U85_00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A4U85_00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A4U85_00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A4U85_00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A4U85_00485	COG0753	catalase activity
A4U85_00535	COG0534	Mate efflux family protein
A4U85_00540	COG0436	Aminotransferase
A4U85_00545	COG2733	membrane
A4U85_00560	COG2918	glutathione biosynthetic process
A4U85_00570	COG3501	Rhs element vgr protein
A4U85_00580	COG3179	chitinase
A4U85_00595	COG3150	esterase
A4U85_00605	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
A4U85_00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4U85_00630	COG2233	PERMEase
A4U85_00635	COG2351	hydroxyisourate hydrolase activity
A4U85_00670	COG3706	GGDEF domain
A4U85_00685	COG1393	Belongs to the ArsC family
A4U85_00690	COG0708	Exodeoxyribonuclease III
A4U85_00710	COG0189	ligase activity
A4U85_00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A4U85_00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A4U85_00755	COG4942	peptidase
A4U85_00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4U85_00775	COG2119	membrane
A4U85_00780	COG4774	siderophore transport
A4U85_00785	COG0426	domain, Protein
A4U85_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A4U85_00830	COG1902	pentaerythritol trinitrate reductase activity
A4U85_00835	COG1519	Transferase
A4U85_00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A4U85_00845	COG0668	transmembrane transport
A4U85_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A4U85_00860	COG1335	isochorismatase
A4U85_00865	COG1522	sequence-specific DNA binding
A4U85_00890	COG0784	Response regulator, receiver
A4U85_00890	COG2198	Histidine kinase
A4U85_00890	COG2205	protein histidine kinase activity
A4U85_00895	COG3162	membrane
A4U85_00900	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A4U85_00910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A4U85_00920	COG3706	GGDEF domain
A4U85_00925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A4U85_00930	COG1309	transcriptional regulator
A4U85_00950	COG0351	phosphomethylpyrimidine kinase
A4U85_00950	COG0352	thiamine-phosphate diphosphorylase activity
A4U85_00950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A4U85_00960	COG2814	Major facilitator Superfamily
A4U85_01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A4U85_01020	COG1113	amino acid transport
A4U85_01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A4U85_01035	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_01045	COG1335	isochorismatase
A4U85_01075	COG2814	Major facilitator Superfamily
A4U85_01080	COG0583	DNA-binding transcription factor activity
A4U85_01100	COG0667	Aldo Keto reductase
A4U85_01130	COG1733	regulation of RNA biosynthetic process
A4U85_01135	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4U85_01205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A4U85_01245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A4U85_01275	COG0427	acetyl-CoA hydrolase
A4U85_01285	COG0745	RESPONSE REGULATOR receiver
A4U85_01295	COG0659	secondary active sulfate transmembrane transporter activity
A4U85_01300	COG4221	oxidoreductase activity
A4U85_01310	COG0488	(ABC) transporter
A4U85_01375	COG0833	amino acid
A4U85_01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A4U85_01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A4U85_01440	COG2226	methyltransferase
A4U85_01490	COG0070	glutamate synthase
A4U85_01490	COG0069	glutamate synthase activity
A4U85_01490	COG0067	glutamate synthase
A4U85_01495	COG0493	'glutamate synthase
A4U85_01505	COG1704	LemA family
A4U85_01510	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A4U85_01530	COG3307	-O-antigen
A4U85_01550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A4U85_01560	COG0194	GDP metabolic process
A4U85_01610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A4U85_01630	COG5380	lipid catabolic process
A4U85_01635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A4U85_01660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A4U85_01665	COG0277	FAD linked oxidase domain protein
A4U85_01675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A4U85_01680	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4U85_01695	COG1289	transmembrane transporter activity
A4U85_01705	COG0628	permease
A4U85_01710	COG1192	Involved in chromosome partitioning
A4U85_01740	COG0833	amino acid
A4U85_01745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A4U85_01750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A4U85_01760	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_01800	COG0583	DNA-binding transcription factor activity
A4U85_01840	COG0517	IMP dehydrogenase activity
A4U85_01845	COG1983	PspC domain protein
A4U85_01855	COG1960	acyl-CoA dehydrogenase activity
A4U85_01870	COG0408	coproporphyrinogen oxidase activity
A4U85_01890	COG0513	Belongs to the DEAD box helicase family
A4U85_01900	COG1127	ABC transporter
A4U85_01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A4U85_01915	COG2854	intermembrane phospholipid transfer
A4U85_01925	COG0598	Magnesium transport protein CorA
A4U85_01935	COG0494	nUDIX hydrolase
A4U85_01940	COG1040	competence protein
A4U85_01945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A4U85_01965	COG1946	Acyl-CoA thioesterase
A4U85_01970	COG1301	dicarboxylic acid transport
A4U85_01985	COG1959	2 iron, 2 sulfur cluster binding
A4U85_01990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4U85_01990	COG1017	nitric oxide dioxygenase activity
A4U85_01995	COG0433	COG0433 Predicted ATPase
A4U85_02000	COG0626	cystathionine gamma-synthase activity
A4U85_02120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A4U85_02130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A4U85_02155	COG1960	acyl-CoA dehydrogenase activity
A4U85_02160	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A4U85_02190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A4U85_02195	COG0339	signal peptide processing
A4U85_02200	COG0557	exoribonuclease II activity
A4U85_02245	COG0179	Fumarylacetoacetate (FAA) hydrolase
A4U85_02250	COG2169	Transcriptional regulator
A4U85_02255	COG0697	spore germination
A4U85_02260	COG1295	ribonuclease BN
A4U85_02295	COG1702	phosphate starvation-inducible protein PhoH
A4U85_02305	COG1196	nuclear chromosome segregation
A4U85_02305	COG0741	lytic transglycosylase activity
A4U85_02305	COG0739	heme binding
A4U85_02335	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A4U85_02340	COG1183	phosphatidylcholine synthase activity
A4U85_02385	COG1960	acyl-CoA dehydrogenase activity
A4U85_02390	COG1309	transcriptional regulator
A4U85_02405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A4U85_02410	COG1960	acyl-CoA dehydrogenase activity
A4U85_02430	COG2969	positive regulation of protein catabolic process
A4U85_02440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A4U85_02455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A4U85_02460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A4U85_02480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A4U85_02490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A4U85_02495	COG1408	metallophosphoesterase
A4U85_02505	COG2199	diguanylate cyclase activity
A4U85_02550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4U85_02550	COG3453	Protein conserved in bacteria
A4U85_02565	COG1607	acyl-coa hydrolase
A4U85_02595	COG2350	Protein conserved in bacteria
A4U85_02605	COG0613	PHP domain protein
A4U85_02610	COG3781	membrane
A4U85_02620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A4U85_02625	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A4U85_02635	COG1862	Preprotein translocase
A4U85_02670	COG2205	protein histidine kinase activity
A4U85_02675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A4U85_02695	COG0726	polysaccharide deacetylase
A4U85_02700	COG0463	Glycosyl transferase, family 2
A4U85_02705	COG0438	transferase activity, transferring glycosyl groups
A4U85_02770	COG0625	glutathione transferase activity
A4U85_02775	COG0583	DNA-binding transcription factor activity
A4U85_02780	COG1960	acyl-CoA dehydrogenase activity
A4U85_02785	COG1960	acyl-CoA dehydrogenase activity
A4U85_02795	COG2205	protein histidine kinase activity
A4U85_02800	COG0745	RESPONSE REGULATOR receiver
A4U85_02805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A4U85_02825	COG2096	Adenosyltransferase
A4U85_02830	COG4206	TonB-dependent receptor
A4U85_02840	COG0133	tryptophan synthase activity
A4U85_02875	COG0285	dihydrofolate synthase activity
A4U85_02895	COG0450	alkyl hydroperoxide reductase
A4U85_02910	COG0477	Major facilitator Superfamily
A4U85_02915	COG1272	protein, Hemolysin III
A4U85_02945	COG0183	Belongs to the thiolase family
A4U85_02950	COG2207	Transcriptional regulator
A4U85_02970	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A4U85_02990	COG0183	Belongs to the thiolase family
A4U85_03000	COG2885	chlorophyll binding
A4U85_03000	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A4U85_03010	COG1690	Belongs to the RtcB family
A4U85_03015	COG0833	amino acid
A4U85_03025	COG2233	PERMEase
A4U85_03055	COG2094	Belongs to the DNA glycosylase MPG family
A4U85_03060	COG4772	TonB-dependent receptor
A4U85_03065	COG1902	pentaerythritol trinitrate reductase activity
A4U85_03080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A4U85_03085	COG0354	folic acid binding
A4U85_03095	COG3189	MarR family transcriptional regulator
A4U85_03100	COG2824	Alkylphosphonate utilization operon protein PhnA
A4U85_03105	COG3422	double-strand break repair
A4U85_03145	COG0840	transmembrane signaling receptor activity
A4U85_03165	COG5510	response to toxic substance
A4U85_03175	COG2832	Protein of unknown function (DUF454)
A4U85_03180	COG1376	ErfK ybiS ycfS ynhG family protein
A4U85_03230	COG1289	transmembrane transporter activity
A4U85_03235	COG2814	Major facilitator Superfamily
A4U85_03250	COG1115	amino acid carrier protein
A4U85_03255	COG1752	Esterase of the alpha-beta hydrolase superfamily
A4U85_03260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A4U85_03265	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A4U85_03290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A4U85_03300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A4U85_03305	COG1077	Cell shape determining protein MreB Mrl
A4U85_03310	COG1792	Involved in formation and maintenance of cell shape
A4U85_03315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A4U85_03320	COG0424	maF-like protein
A4U85_03325	COG1530	ribonuclease E activity
A4U85_03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A4U85_03355	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4U85_03380	COG2207	Transcriptional regulator
A4U85_03400	COG1113	amino acid transport
A4U85_03405	COG2828	Protein conserved in bacteria
A4U85_03410	COG0142	geranyltranstransferase activity
A4U85_03415	COG2315	Protein conserved in bacteria
A4U85_03430	COG1752	Esterase of the alpha-beta hydrolase superfamily
A4U85_03450	COG2194	sulfuric ester hydrolase activity
A4U85_03455	COG0745	RESPONSE REGULATOR receiver
A4U85_03460	COG0642	Histidine kinase
A4U85_03470	COG0004	ammonium transporteR
A4U85_03475	COG0583	DNA-binding transcription factor activity
A4U85_03495	COG0525	valine-tRNA ligase activity
A4U85_03505	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_03515	COG0393	Putative heavy-metal-binding
A4U85_03520	COG0393	Putative heavy-metal-binding
A4U85_03525	COG1538	Outer membrane efflux protein
A4U85_03535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_03540	COG0671	phosphoesterase, PA-phosphatase related
A4U85_03570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A4U85_03585	COG1648	precorrin-2 dehydrogenase activity
A4U85_03585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A4U85_03590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A4U85_03605	COG0531	amino acid
A4U85_03620	COG0321	lipoyl(octanoyl) transferase activity
A4U85_03625	COG2921	Belongs to the UPF0250 family
A4U85_03660	COG2009	succinate dehydrogenase
A4U85_03665	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A4U85_03670	COG1053	succinate dehydrogenase
A4U85_03675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A4U85_03690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4U85_03710	COG2354	Protein conserved in bacteria
A4U85_03715	COG2321	neutral zinc metallopeptidase
A4U85_03735	COG2843	Capsule synthesis protein
A4U85_03750	COG0589	response to stress
A4U85_03770	COG0505	Belongs to the CarA family
A4U85_03795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A4U85_03800	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A4U85_03850	COG0477	Major facilitator Superfamily
A4U85_03855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A4U85_03875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A4U85_03900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4U85_03905	COG0584	glycerophosphoryl diester phosphodiesterase
A4U85_03925	COG0741	lytic transglycosylase activity
A4U85_03945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A4U85_03960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A4U85_03990	COG0778	Nitroreductase
A4U85_04005	COG1929	Belongs to the glycerate kinase type-1 family
A4U85_04010	COG0243	molybdopterin cofactor binding
A4U85_04015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A4U85_04020	COG3339	Conserved Protein
A4U85_04030	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A4U85_04045	COG1113	amino acid transport
A4U85_04055	COG0019	diaminopimelate decarboxylase activity
A4U85_04070	COG2267	carboxylic ester hydrolase activity
A4U85_04075	COG1280	lysine exporter protein (LysE YggA)
A4U85_04080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A4U85_04110	COG0463	Glycosyl transferase, family 2
A4U85_04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_04160	COG4591	ABC-type transport system involved in lipoprotein release permease component
A4U85_04165	COG1136	(ABC) transporter
A4U85_04170	COG2333	competence protein COMEC
A4U85_04170	COG0658	competence protein
A4U85_04180	COG0616	signal peptide processing
A4U85_04180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A4U85_04185	COG0596	Alpha beta hydrolase
A4U85_04190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A4U85_04200	COG0628	permease
A4U85_04235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A4U85_04255	COG0823	Involved in the tonB-independent uptake of proteins
A4U85_04275	COG0824	Thioesterase
A4U85_04280	COG1473	amidohydrolase
A4U85_04300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A4U85_04300	COG0047	phosphoribosylformylglycinamidine synthase activity
A4U85_04305	COG2814	Major facilitator Superfamily
A4U85_04315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A4U85_04320	COG1024	Enoyl-CoA hydratase
A4U85_04325	COG1056	cytidyltransferase-related domain
A4U85_04325	COG1051	belongs to the nudix hydrolase family
A4U85_04335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A4U85_04350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A4U85_04365	COG4625	pathogenesis
A4U85_04370	COG0583	DNA-binding transcription factor activity
A4U85_04375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A4U85_04380	COG4208	sulfate ABC transporter
A4U85_04385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A4U85_04395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A4U85_04400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A4U85_04405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A4U85_04425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A4U85_04440	COG0681	Belongs to the peptidase S26 family
A4U85_04455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A4U85_04465	COG1381	Involved in DNA repair and RecF pathway recombination
A4U85_04470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A4U85_04480	COG4221	oxidoreductase activity
A4U85_04505	COG0443	Heat shock 70 kDa protein
A4U85_04535	COG0556	nucleotide-excision repair
A4U85_04590	COG2070	2-Nitropropane dioxygenase
A4U85_04620	COG1215	transferase activity, transferring glycosyl groups
A4U85_04635	COG0415	Belongs to the DNA photolyase family
A4U85_04645	COG1252	NADH dehydrogenase
A4U85_04650	COG1686	Belongs to the peptidase S11 family
A4U85_04665	COG1187	pseudouridine synthase activity
A4U85_04685	COG0477	Major facilitator Superfamily
A4U85_04690	COG0583	DNA-binding transcription factor activity
A4U85_04705	COG0612	Peptidase, M16
A4U85_04730	COG0352	thiamine-phosphate diphosphorylase activity
A4U85_04765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4U85_04775	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4U85_04790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A4U85_04795	COG0076	glutamate decarboxylase activity
A4U85_04805	COG1522	sequence-specific DNA binding
A4U85_04810	COG3961	Belongs to the TPP enzyme family
A4U85_04815	COG1113	amino acid transport
A4U85_04820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A4U85_04825	COG0573	inorganic phosphate transmembrane transporter activity
A4U85_04835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A4U85_04840	COG0616	signal peptide processing
A4U85_04875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A4U85_04880	COG1686	Belongs to the peptidase S11 family
A4U85_04905	COG0583	DNA-binding transcription factor activity
A4U85_04910	COG1067	ATP-dependent peptidase activity
A4U85_04935	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A4U85_04955	COG1966	Carbon starvation protein
A4U85_04960	COG2879	small protein
A4U85_04990	COG1741	Belongs to the pirin family
A4U85_05000	COG2964	Protein conserved in bacteria
A4U85_05015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A4U85_05020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4U85_05025	COG4605	iron ion homeostasis
A4U85_05030	COG4604	ABC transporter, ATP-binding protein
A4U85_05035	COG4607	ABC-type enterochelin transport system periplasmic component
A4U85_05040	COG4774	siderophore transport
A4U85_05050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A4U85_05055	COG1021	2,3-dihydroxybenzoate-AMP ligase
A4U85_05060	COG1535	isochorismatase
A4U85_05060	COG3433	isochorismatase activity
A4U85_05075	COG1132	(ABC) transporter
A4U85_05080	COG5265	(ABC) transporter
A4U85_05085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A4U85_05095	COG1169	isochorismate synthase
A4U85_05110	COG3739	integral membrane protein
A4U85_05140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A4U85_05170	COG0308	aminopeptidase N
A4U85_05175	COG0512	Glutamine amidotransferase of anthranilate synthase
A4U85_05185	COG3104	oligopeptide transport
A4U85_05200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A4U85_05235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A4U85_05240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A4U85_05245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A4U85_05265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A4U85_05270	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A4U85_05275	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A4U85_05290	COG1960	acyl-CoA dehydrogenase activity
A4U85_05295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A4U85_05300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4U85_05315	COG2223	nitrite transmembrane transporter activity
A4U85_05325	COG0024	Methionine aminopeptidase
A4U85_05330	COG0052	Belongs to the universal ribosomal protein uS2 family
A4U85_05345	COG2207	Transcriptional regulator
A4U85_05370	COG2951	lytic endotransglycosylase activity
A4U85_05375	COG0772	Belongs to the SEDS family
A4U85_05390	COG0842	Transport permease protein
A4U85_05395	COG1131	(ABC) transporter
A4U85_05400	COG0582	viral genome integration into host DNA
A4U85_05405	COG3617	BRO family, N-terminal domain
A4U85_05435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A4U85_05785	COG1538	Outer membrane efflux protein
A4U85_05795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_05810	COG4215	(ABC) transporter
A4U85_05815	COG4160	amino acid transport
A4U85_05820	COG4598	ABC transporter
A4U85_05830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A4U85_05840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4U85_05855	COG1720	tRNA m6t6A37 methyltransferase activity
A4U85_05870	COG3111	PFAM Bacterial OB fold (BOF) protein
A4U85_05875	COG0745	RESPONSE REGULATOR receiver
A4U85_05880	COG0642	Histidine kinase
A4U85_05890	COG0494	nUDIX hydrolase
A4U85_05900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A4U85_05905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A4U85_05910	COG3139	Protein of unknown function (DUF1315)
A4U85_05915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A4U85_05920	COG1301	dicarboxylic acid transport
A4U85_05925	COG1960	acyl-CoA dehydrogenase activity
A4U85_05930	COG2819	hydrolase of the alpha beta superfamily
A4U85_05940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A4U85_05950	COG2195	Cleaves the N-terminal amino acid of tripeptides
A4U85_05955	COG1234	tRNA 3'-trailer cleavage
A4U85_05985	COG2363	Small membrane protein
A4U85_06005	COG0513	Belongs to the DEAD box helicase family
A4U85_06015	COG0778	Nitroreductase
A4U85_06045	COG1286	toxin biosynthetic process
A4U85_06070	COG4783	chaperone-mediated protein folding
A4U85_06075	COG1610	YqeY-like protein
A4U85_06080	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A4U85_06175	COG3111	PFAM Bacterial OB fold (BOF) protein
A4U85_06200	COG3243	poly(R)-hydroxyalkanoic acid synthase
A4U85_06205	COG0786	glutamate:sodium symporter activity
A4U85_06215	COG2186	Transcriptional regulator
A4U85_06270	COG0477	Major facilitator Superfamily
A4U85_06275	COG1051	belongs to the nudix hydrolase family
A4U85_06305	COG2995	paraquat-inducible protein a
A4U85_06310	COG3008	intermembrane lipid transfer
A4U85_06310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A4U85_06320	COG2351	hydroxyisourate hydrolase activity
A4U85_06360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A4U85_06370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A4U85_06375	COG0642	Histidine kinase
A4U85_06380	COG0745	RESPONSE REGULATOR receiver
A4U85_06400	COG1794	racemase activity, acting on amino acids and derivatives
A4U85_06430	COG1301	dicarboxylic acid transport
A4U85_06440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4U85_06445	COG2011	ABC-type metal ion transport system permease component
A4U85_06450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A4U85_06455	COG1464	Belongs to the NlpA lipoprotein family
A4U85_06460	COG0151	Belongs to the GarS family
A4U85_06465	COG0138	bifunctional purine biosynthesis protein purh
A4U85_06470	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A4U85_06500	COG2308	Evidence 4 Homologs of previously reported genes of
A4U85_06510	COG1305	Transglutaminase-like
A4U85_06520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A4U85_06525	COG0305	Participates in initiation and elongation during chromosome replication
A4U85_06550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A4U85_06560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A4U85_06565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A4U85_06590	COG1649	PFAM Uncharacterised BCR, COG1649
A4U85_06590	COG0726	polysaccharide deacetylase
A4U85_06595	COG1215	transferase activity, transferring glycosyl groups
A4U85_06600	COG3658	cytochrome
A4U85_06610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A4U85_06630	COG0583	DNA-binding transcription factor activity
A4U85_06665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A4U85_06670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_06695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A4U85_06700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A4U85_06710	COG2205	protein histidine kinase activity
A4U85_06715	COG0745	RESPONSE REGULATOR receiver
A4U85_06720	COG0174	glutamine synthetase
A4U85_06740	COG0729	surface antigen
A4U85_06765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A4U85_06770	COG2814	Major facilitator Superfamily
A4U85_06785	COG0583	DNA-binding transcription factor activity
A4U85_06800	COG1187	pseudouridine synthase activity
A4U85_06820	COG0802	atpase or kinase
A4U85_06825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A4U85_06835	COG1923	regulation of RNA biosynthetic process
A4U85_06840	COG0697	spore germination
A4U85_06855	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A4U85_06870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A4U85_06870	COG0519	Catalyzes the synthesis of GMP from XMP
A4U85_06875	COG4302	ethanolamine ammonia-lyase activity
A4U85_06880	COG4303	Ethanolamine ammonia lyase large subunit
A4U85_06885	COG0531	amino acid
A4U85_06905	COG1454	alcohol dehydrogenase
A4U85_06910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A4U85_06935	COG0308	aminopeptidase N
A4U85_06975	COG1605	Chorismate mutase
A4U85_06990	COG1309	transcriptional regulator
A4U85_07000	COG0668	transmembrane transport
A4U85_07030	COG4773	Receptor
A4U85_07050	COG0488	(ABC) transporter
A4U85_07055	COG0589	response to stress
A4U85_07075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A4U85_07085	COG3135	benzoate transporter
A4U85_07090	COG1522	sequence-specific DNA binding
A4U85_07105	COG0583	DNA-binding transcription factor activity
A4U85_07115	COG0183	Belongs to the thiolase family
A4U85_07145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A4U85_07155	COG0824	Thioesterase
A4U85_07160	COG1454	alcohol dehydrogenase
A4U85_07170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A4U85_07190	COG0069	glutamate synthase activity
A4U85_07210	COG2814	Major facilitator Superfamily
A4U85_07225	COG0511	ligase activity, forming carbon-carbon bonds
A4U85_07240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A4U85_07240	COG1116	anion transmembrane transporter activity
A4U85_07245	COG0745	RESPONSE REGULATOR receiver
A4U85_07255	COG2146	nitrite reductase [NAD(P)H] activity
A4U85_07255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A4U85_07260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A4U85_07265	COG0243	molybdopterin cofactor binding
A4U85_07280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A4U85_07295	COG0315	cyclic pyranopterin monophosphate synthase activity
A4U85_07295	COG0521	Mo-molybdopterin cofactor biosynthetic process
A4U85_07300	COG0303	'Molybdopterin
A4U85_07310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4U85_07315	COG0697	spore germination
A4U85_07335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A4U85_07340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A4U85_07395	COG2204	response regulator
A4U85_07400	COG3852	Histidine kinase
A4U85_07420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A4U85_07425	COG0575	Belongs to the CDS family
A4U85_07460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A4U85_07475	COG2137	regulation of response to DNA damage stimulus
A4U85_07485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A4U85_07490	COG1011	Hydrolase
A4U85_07515	COG1522	sequence-specific DNA binding
A4U85_07525	COG1113	amino acid transport
A4U85_07540	COG0659	secondary active sulfate transmembrane transporter activity
A4U85_07545	COG2135	peptidase activity
A4U85_07560	COG3300	MHYT domain
A4U85_07560	COG5001	Diguanylate cyclase
A4U85_07580	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
A4U85_07580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4U85_07580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4U85_07585	COG1105	Belongs to the carbohydrate kinase PfkB family
A4U85_07590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4U85_07590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A4U85_07620	COG0024	Methionine aminopeptidase
A4U85_07625	COG0583	DNA-binding transcription factor activity
A4U85_07635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A4U85_07640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A4U85_07645	COG0516	GMP reductase activity
A4U85_07645	COG0517	IMP dehydrogenase activity
A4U85_07670	COG0552	protein localization to endoplasmic reticulum
A4U85_07680	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A4U85_07690	COG4890	Cyd operon protein YbgT
A4U85_07695	COG1294	oxidase, subunit
A4U85_07710	COG1585	Membrane protein implicated in regulation of membrane protease activity
A4U85_07720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A4U85_07725	COG4774	siderophore transport
A4U85_07740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A4U85_07745	COG0569	domain protein
A4U85_07750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A4U85_07780	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A4U85_07785	COG0542	response to heat
A4U85_07795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A4U85_07810	COG0446	pyridine nucleotide-disulphide oxidoreductase
A4U85_07810	COG1902	pentaerythritol trinitrate reductase activity
A4U85_07855	COG2323	membrane
A4U85_07860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A4U85_07870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A4U85_07875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A4U85_07880	COG0183	Belongs to the thiolase family
A4U85_07885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A4U85_07890	COG0596	Alpha beta hydrolase
A4U85_07895	COG2271	Major facilitator Superfamily
A4U85_07900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A4U85_07905	COG3485	protocatechuate 3,4-dioxygenase
A4U85_07910	COG3485	protocatechuate 3,4-dioxygenase
A4U85_07915	COG0710	3-dehydroquinate dehydratase activity
A4U85_07920	COG3420	alginic acid biosynthetic process
A4U85_07925	COG3659	wide pore channel activity
A4U85_07930	COG4993	Dehydrogenase
A4U85_07940	COG2391	methyltransferase activity
A4U85_07955	COG1414	Transcriptional regulator
A4U85_07960	COG0583	DNA-binding transcription factor activity
A4U85_07965	COG1960	acyl-CoA dehydrogenase activity
A4U85_07990	COG2814	Major facilitator Superfamily
A4U85_08000	COG0154	amidase activity
A4U85_08020	COG4638	Rieske (2fe-2S)
A4U85_08030	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_08050	COG3733	amine oxidase
A4U85_08060	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_08070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A4U85_08075	COG0183	Belongs to the thiolase family
A4U85_08080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A4U85_08085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A4U85_08095	COG4829	muconolactone delta-isomerase
A4U85_08100	COG4948	Mandelate Racemase Muconate Lactonizing
A4U85_08105	COG0583	DNA-binding transcription factor activity
A4U85_08115	COG2186	Transcriptional regulator
A4U85_08135	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_08150	COG0446	pyridine nucleotide-disulphide oxidoreductase
A4U85_08150	COG1902	pentaerythritol trinitrate reductase activity
A4U85_08165	COG0789	Transcriptional regulator
A4U85_08190	COG1309	transcriptional regulator
A4U85_08195	COG0583	DNA-binding transcription factor activity
A4U85_08200	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08205	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08210	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08220	COG1960	acyl-CoA dehydrogenase activity
A4U85_08230	COG0318	PFAM AMP-dependent synthetase and ligase
A4U85_08245	COG2831	hemolysin activation secretion protein
A4U85_08250	COG3210	domain, Protein
A4U85_08300	COG0583	DNA-binding transcription factor activity
A4U85_08315	COG1566	PFAM secretion protein HlyD family protein
A4U85_08330	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_08335	COG0129	dihydroxy-acid dehydratase activity
A4U85_08345	COG0583	DNA-binding transcription factor activity
A4U85_08350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A4U85_08360	COG2084	Dehydrogenase
A4U85_08365	COG2207	Transcriptional regulator
A4U85_08380	COG1064	alcohol dehydrogenase
A4U85_08395	COG1120	ATPase activity
A4U85_08415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A4U85_08460	COG1401	restriction endodeoxyribonuclease activity
A4U85_08530	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A4U85_08575	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
A4U85_08590	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08605	COG2207	Transcriptional regulator
A4U85_08615	COG2205	protein histidine kinase activity
A4U85_08620	COG0745	RESPONSE REGULATOR receiver
A4U85_08625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_08630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A4U85_08670	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A4U85_08680	COG0753	catalase activity
A4U85_08695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A4U85_08755	COG3433	isochorismatase activity
A4U85_08755	COG1535	isochorismatase
A4U85_08760	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08765	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A4U85_08770	COG4149	molybdate abc transporter
A4U85_08775	COG0725	ABC transporter, periplasmic molybdate-binding protein
A4U85_08785	COG4638	Rieske (2fe-2S)
A4U85_08790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A4U85_08795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4U85_08795	COG0543	2 iron, 2 sulfur cluster binding
A4U85_08810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_08820	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08825	COG0412	Dienelactone hydrolase
A4U85_08835	COG2207	Transcriptional regulator
A4U85_08840	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_08845	COG2610	gluconate transmembrane transporter activity
A4U85_08855	COG1309	transcriptional regulator
A4U85_08875	COG0583	DNA-binding transcription factor activity
A4U85_08890	COG2031	fatty acid transporter
A4U85_08895	COG0183	Belongs to the thiolase family
A4U85_08900	COG0583	DNA-binding transcription factor activity
A4U85_08905	COG0583	DNA-binding transcription factor activity
A4U85_08920	COG1027	Aspartate ammonia-lyase
A4U85_08930	COG0477	Major facilitator Superfamily
A4U85_08950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A4U85_08955	COG4521	taurine ABC transporter
A4U85_08980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A4U85_08985	COG1733	regulation of RNA biosynthetic process
A4U85_08990	COG2207	Transcriptional regulator
A4U85_08990	COG3708	Transcriptional regulator
A4U85_09005	COG0730	response to heat
A4U85_09015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4U85_09015	COG3453	Protein conserved in bacteria
A4U85_09025	COG3781	membrane
A4U85_09030	COG1063	alcohol dehydrogenase
A4U85_09040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4U85_09045	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4U85_09050	COG0022	dehydrogenase e1 component
A4U85_09055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A4U85_09060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A4U85_09075	COG3706	GGDEF domain
A4U85_09095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A4U85_09120	COG2226	methyltransferase
A4U85_09175	COG0842	Transport permease protein
A4U85_09180	COG0842	Transport permease protein
A4U85_09185	COG1131	(ABC) transporter
A4U85_09200	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A4U85_09205	COG4773	Receptor
A4U85_09225	COG0730	response to heat
A4U85_09230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A4U85_09245	COG0406	alpha-ribazole phosphatase activity
A4U85_09265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A4U85_09295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A4U85_09305	COG4264	IucA IucC family
A4U85_09310	COG4264	IucA IucC family
A4U85_09330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A4U85_09345	COG1960	acyl-CoA dehydrogenase activity
A4U85_09350	COG1960	acyl-CoA dehydrogenase activity
A4U85_09355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A4U85_09360	COG2207	Transcriptional regulator
A4U85_09365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A4U85_09370	COG0776	regulation of translation
A4U85_09395	COG0822	iron-sulfur transferase activity
A4U85_09400	COG0316	Belongs to the HesB IscA family
A4U85_09430	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A4U85_09450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A4U85_09455	COG0702	epimerase
A4U85_09490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A4U85_09500	COG0339	signal peptide processing
A4U85_09545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A4U85_09550	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A4U85_09580	COG0776	regulation of translation
A4U85_09600	COG0590	tRNA wobble adenosine to inosine editing
A4U85_09630	COG2165	general secretion pathway protein
A4U85_09645	COG0084	hydrolase, TatD family'
A4U85_09665	COG1663	tetraacyldisaccharide 4'-kinase activity
A4U85_09670	COG1132	(ABC) transporter
A4U85_09680	COG0811	peptide transport
A4U85_09685	COG1475	DNA binding
A4U85_09690	COG1192	Involved in chromosome partitioning
A4U85_09700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A4U85_09715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A4U85_09720	COG0191	fructose-bisphosphate aldolase activity
A4U85_09740	COG0424	maF-like protein
A4U85_09745	COG2850	peptidyl-arginine hydroxylation
A4U85_09755	COG0640	Transcriptional regulator
A4U85_09765	COG3619	membrane
A4U85_09770	COG3122	Protein conserved in bacteria
A4U85_09775	COG1132	(ABC) transporter
A4U85_09795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A4U85_09800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A4U85_09810	COG0506	proline dehydrogenase activity
A4U85_09810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A4U85_09810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A4U85_09815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A4U85_09830	COG3698	Phosphodiester glycosidase
A4U85_09840	COG2353	YceI-like domain
A4U85_09850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A4U85_09895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A4U85_09895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A4U85_09920	COG3539	Fimbrial protein
A4U85_09925	COG3121	Chaperone
A4U85_09950	COG0697	spore germination
A4U85_09960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A4U85_09970	COG0583	DNA-binding transcription factor activity
A4U85_10000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A4U85_10010	COG1061	Type III restriction enzyme res subunit
A4U85_10015	COG1002	Type II restriction enzyme, methylase subunits
A4U85_10030	COG4584	PFAM Integrase catalytic
A4U85_10035	COG1484	DNA-dependent DNA replication
A4U85_10045	COG1309	transcriptional regulator
A4U85_10060	COG1522	sequence-specific DNA binding
A4U85_10070	COG1126	abc transporter atp-binding protein
A4U85_10075	COG0765	amino acid transport
A4U85_10080	COG0765	amino acid transport
A4U85_10110	COG1464	Belongs to the NlpA lipoprotein family
A4U85_10120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A4U85_10125	COG2011	ABC-type metal ion transport system permease component
A4U85_10130	COG0012	GTP binding
A4U85_10155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A4U85_10195	COG0386	Belongs to the glutathione peroxidase family
A4U85_10205	COG0436	Aminotransferase
A4U85_10245	COG3634	alkyl hydroperoxide reductase activity
A4U85_10260	COG0583	DNA-binding transcription factor activity
A4U85_10265	COG0798	PFAM Bile acid sodium symporter
A4U85_10270	COG0640	Transcriptional regulator
A4U85_10285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A4U85_10295	COG0583	DNA-binding transcription factor activity
A4U85_10305	COG1953	Uracil, thiamine, allantoin
A4U85_10315	COG2175	clavaminate synthase activity
A4U85_10320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A4U85_10325	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A4U85_10330	COG4521	taurine ABC transporter
A4U85_10340	COG0477	Major facilitator Superfamily
A4U85_10360	COG1271	oxidase subunit
A4U85_10365	COG1294	oxidase, subunit
A4U85_10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4U85_10415	COG3052	prosthetic group binding
A4U85_10420	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A4U85_10430	COG0583	DNA-binding transcription factor activity
A4U85_10440	COG2814	Major facilitator Superfamily
A4U85_10460	COG1346	cytolysis
A4U85_10470	COG0583	DNA-binding transcription factor activity
A4U85_10475	COG0625	glutathione transferase activity
A4U85_10480	COG0625	glutathione transferase activity
A4U85_10485	COG0583	DNA-binding transcription factor activity
A4U85_10500	COG1045	serine acetyltransferase
A4U85_10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A4U85_10510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A4U85_10515	COG1280	lysine exporter protein (LysE YggA)
A4U85_10525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4U85_10530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4U85_10535	COG1126	abc transporter atp-binding protein
A4U85_10540	COG0765	amino acid transport
A4U85_10545	COG0765	amino acid transport
A4U85_10560	COG2205	protein histidine kinase activity
A4U85_10560	COG0784	Response regulator, receiver
A4U85_10580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A4U85_10600	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_10650	COG0583	DNA-binding transcription factor activity
A4U85_10670	COG0318	PFAM AMP-dependent synthetase and ligase
A4U85_10675	COG1309	transcriptional regulator
A4U85_10680	COG1960	acyl-CoA dehydrogenase activity
A4U85_10685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A4U85_10690	COG1024	Enoyl-CoA hydratase
A4U85_10705	COG0583	DNA-binding transcription factor activity
A4U85_10720	COG1960	acyl-CoA dehydrogenase activity
A4U85_10730	COG2814	Major facilitator Superfamily
A4U85_10740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A4U85_10745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A4U85_10750	COG2814	Major facilitator Superfamily
A4U85_10755	COG1960	acyl-CoA dehydrogenase activity
A4U85_10760	COG1024	Enoyl-CoA hydratase
A4U85_10765	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_10770	COG1250	3-hydroxyacyl-CoA dehydrogenase
A4U85_10775	COG0183	Belongs to the thiolase family
A4U85_10785	COG2814	Major facilitator Superfamily
A4U85_10795	COG1024	Enoyl-CoA hydratase
A4U85_10810	COG1960	acyl-CoA dehydrogenase activity
A4U85_10815	COG2814	Major facilitator Superfamily
A4U85_10820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A4U85_10825	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A4U85_10840	COG3842	ATPase activity
A4U85_10845	COG1840	ABC-type Fe3 transport system, periplasmic component
A4U85_10855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4U85_10860	COG1414	Transcriptional regulator
A4U85_10870	COG0583	DNA-binding transcription factor activity
A4U85_10875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A4U85_10880	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_10890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A4U85_10895	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_10900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A4U85_10905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_10910	COG2267	carboxylic ester hydrolase activity
A4U85_10930	COG3038	cytochrome b561
A4U85_10935	COG0753	catalase activity
A4U85_10940	COG2271	Major facilitator Superfamily
A4U85_10945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A4U85_10950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A4U85_10965	COG2207	Transcriptional regulator
A4U85_11005	COG2050	protein possibly involved in aromatic compounds catabolism
A4U85_11015	COG3327	negative regulation of DNA-templated transcription, initiation
A4U85_11020	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A4U85_11025	COG0183	Belongs to the thiolase family
A4U85_11030	COG1250	3-hydroxyacyl-CoA dehydrogenase
A4U85_11035	COG1024	Enoyl-CoA hydratase
A4U85_11040	COG1024	Enoyl-CoA hydratase
A4U85_11045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4U85_11050	COG2151	metal-sulfur cluster biosynthetic enzyme
A4U85_11055	COG3396	Phenylacetate-CoA oxygenase
A4U85_11060	COG3460	Phenylacetate-CoA oxygenase
A4U85_11065	COG3396	Phenylacetate-CoA oxygenase
A4U85_11070	COG2030	dehydratase
A4U85_11070	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_11075	COG1760	l-serine dehydratase
A4U85_11080	COG0531	amino acid
A4U85_11085	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_11130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A4U85_11155	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A4U85_11170	COG2807	transmembrane transport
A4U85_11175	COG0590	tRNA wobble adenosine to inosine editing
A4U85_11185	COG0583	DNA-binding transcription factor activity
A4U85_11225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A4U85_11225	COG2885	chlorophyll binding
A4U85_11295	COG1116	anion transmembrane transporter activity
A4U85_11300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4U85_11310	COG0864	Transcriptional regulator
A4U85_11325	COG1733	regulation of RNA biosynthetic process
A4U85_11330	COG2249	NAD(P)H dehydrogenase (quinone) activity
A4U85_11335	COG0439	Biotin carboxylase
A4U85_11350	COG1063	alcohol dehydrogenase
A4U85_11360	COG1309	transcriptional regulator
A4U85_11375	COG3210	domain, Protein
A4U85_11380	COG2831	hemolysin activation secretion protein
A4U85_11385	COG0038	chloride channel
A4U85_11390	COG4770	biotin carboxylase activity
A4U85_11410	COG1914	H( )-stimulated, divalent metal cation uptake system
A4U85_11415	COG0583	DNA-binding transcription factor activity
A4U85_11445	COG1250	3-hydroxyacyl-CoA dehydrogenase
A4U85_11465	COG2814	Major facilitator Superfamily
A4U85_11475	COG1560	Kdo2-lipid A biosynthetic process
A4U85_11485	COG5006	permease, DMT superfamily
A4U85_11490	COG1522	sequence-specific DNA binding
A4U85_11505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A4U85_11590	COG1137	ATPase activity
A4U85_11595	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A4U85_11605	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A4U85_11610	COG0517	IMP dehydrogenase activity
A4U85_11610	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
A4U85_11815	COG5377	YqaJ viral recombinase family
A4U85_11825	COG0210	DNA helicase
A4U85_11905	COG1733	regulation of RNA biosynthetic process
A4U85_11910	COG2814	Major facilitator Superfamily
A4U85_11940	COG1278	Cold shock
A4U85_11945	COG1280	lysine exporter protein (LysE YggA)
A4U85_11980	COG1570	exodeoxyribonuclease VII activity
A4U85_12030	COG0583	DNA-binding transcription factor activity
A4U85_12035	COG4638	Rieske (2fe-2S)
A4U85_12040	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A4U85_12045	COG0543	2 iron, 2 sulfur cluster binding
A4U85_12045	COG0633	Ferredoxin
A4U85_12050	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_12055	COG3135	benzoate transporter
A4U85_12060	COG2814	Major facilitator Superfamily
A4U85_12075	COG1643	Atp-dependent helicase
A4U85_12080	COG0450	alkyl hydroperoxide reductase
A4U85_12090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A4U85_12100	COG3634	alkyl hydroperoxide reductase activity
A4U85_12120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A4U85_12140	COG0625	glutathione transferase activity
A4U85_12150	COG2885	chlorophyll binding
A4U85_12200	COG1765	OsmC-like protein
A4U85_12210	COG0667	Aldo Keto reductase
A4U85_12225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A4U85_12235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A4U85_12245	COG0582	viral genome integration into host DNA
A4U85_12370	COG3566	protein conserved in bacteria
A4U85_12395	COG3567	Phage-associated protein, HI1409 family
A4U85_12400	COG5410	chromosome segregation
A4U85_12480	COG4197	protein conserved in bacteria, prophage-related
A4U85_12485	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A4U85_12550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A4U85_12560	COG3038	cytochrome b561
A4U85_12565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A4U85_12570	COG2252	PERMEase
A4U85_12580	COG2072	flavoprotein involved in K transport
A4U85_12595	COG1741	Belongs to the pirin family
A4U85_12600	COG1309	transcriptional regulator
A4U85_12610	COG0300	oxidoreductase activity
A4U85_12615	COG2072	flavoprotein involved in K transport
A4U85_12620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A4U85_12665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A4U85_12680	COG2814	Major facilitator Superfamily
A4U85_12685	COG1024	Enoyl-CoA hydratase
A4U85_12690	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_12700	COG1960	acyl-CoA dehydrogenase activity
A4U85_12725	COG2186	Transcriptional regulator
A4U85_12730	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_12740	COG4948	Mandelate Racemase Muconate Lactonizing
A4U85_12745	COG2271	Major facilitator Superfamily
A4U85_12750	COG2721	sulfolactate sulfo-lyase activity
A4U85_12755	COG0697	spore germination
A4U85_12790	COG1113	amino acid transport
A4U85_12810	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_12830	COG0531	amino acid
A4U85_12840	COG1113	amino acid transport
A4U85_12880	COG4269	membrane
A4U85_12895	COG1309	transcriptional regulator
A4U85_12920	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
A4U85_12925	COG2184	nucleotidyltransferase activity
A4U85_12980	COG0789	Transcriptional regulator
A4U85_13055	COG0582	viral genome integration into host DNA
A4U85_13065	COG1902	pentaerythritol trinitrate reductase activity
A4U85_13065	COG0446	pyridine nucleotide-disulphide oxidoreductase
A4U85_13075	COG4251	negative regulation of phosphorylation
A4U85_13075	COG3706	GGDEF domain
A4U85_13075	COG2203	Gaf domain
A4U85_13075	COG5001	Diguanylate cyclase
A4U85_13085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A4U85_13105	COG4172	Belongs to the ABC transporter superfamily
A4U85_13110	COG4239	(ABC) transporter, permease
A4U85_13115	COG4174	ABC transporter (Permease)
A4U85_13125	COG1388	LysM domain
A4U85_13125	COG0741	lytic transglycosylase activity
A4U85_13125	COG1388	LysM domain
A4U85_13125	COG0741	lytic transglycosylase activity
A4U85_13130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A4U85_13170	COG0583	DNA-binding transcription factor activity
A4U85_13175	COG1279	arginine transmembrane transporter activity
A4U85_13195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4U85_13200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4U85_13205	COG0006	proline dipeptidase activity
A4U85_13240	COG2194	sulfuric ester hydrolase activity
A4U85_13285	COG0739	heme binding
A4U85_13600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A4U85_13625	COG3384	dioxygenase
A4U85_13635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A4U85_13640	COG2878	Part of a membrane complex involved in electron transport
A4U85_13645	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A4U85_13665	COG0768	penicillin binding
A4U85_13670	COG0742	ribosomal rna small subunit methyltransferase
A4U85_13685	COG0830	nickel cation binding
A4U85_13695	COG0804	urea catabolic process
A4U85_13735	COG1253	flavin adenine dinucleotide binding
A4U85_13740	COG2851	Citrate transporter
A4U85_13785	COG1773	rubredoxin
A4U85_13790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A4U85_13800	COG0583	DNA-binding transcription factor activity
A4U85_13825	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A4U85_13830	COG4181	ATPase activity
A4U85_13875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A4U85_13895	COG0306	phosphate transporter
A4U85_13905	COG3958	Transketolase
A4U85_13910	COG3959	Transketolase, thiamine diphosphate binding domain
A4U85_13915	COG2271	Major facilitator Superfamily
A4U85_13920	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_13925	COG0583	DNA-binding transcription factor activity
A4U85_13940	COG2223	nitrite transmembrane transporter activity
A4U85_13945	COG2207	Transcriptional regulator
A4U85_13950	COG2066	Belongs to the glutaminase family
A4U85_13955	COG0242	peptide deformylase activity
A4U85_13960	COG0477	Major facilitator Superfamily
A4U85_13970	COG0028	Belongs to the TPP enzyme family
A4U85_13985	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_13990	COG2267	carboxylic ester hydrolase activity
A4U85_14000	COG2271	Major facilitator Superfamily
A4U85_14015	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_14035	COG1414	Transcriptional regulator
A4U85_14050	COG1024	Enoyl-CoA hydratase
A4U85_14060	COG1215	transferase activity, transferring glycosyl groups
A4U85_14065	COG1649	PFAM Uncharacterised BCR, COG1649
A4U85_14065	COG0726	polysaccharide deacetylase
A4U85_14075	COG4681	YaeQ
A4U85_14085	COG0523	cobalamin synthesis protein
A4U85_14095	COG1607	acyl-coa hydrolase
A4U85_14105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A4U85_14110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A4U85_14115	COG1309	transcriptional regulator
A4U85_14140	COG2040	homocysteine
A4U85_14145	COG0531	amino acid
A4U85_14190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A4U85_14195	COG0477	Major facilitator Superfamily
A4U85_14315	COG0629	single-stranded DNA binding
A4U85_14360	COG0582	viral genome integration into host DNA
A4U85_14370	COG0405	Gamma-glutamyltransferase
A4U85_14375	COG2814	Major facilitator Superfamily
A4U85_14385	COG2050	protein possibly involved in aromatic compounds catabolism
A4U85_14400	COG1090	epimerase
A4U85_14420	COG0420	3'-5' exonuclease activity
A4U85_14445	COG0735	belongs to the Fur family
A4U85_14450	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A4U85_14475	COG0121	glutamine amidotransferase
A4U85_14490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4U85_14500	COG0210	DNA helicase
A4U85_14505	COG2885	chlorophyll binding
A4U85_14510	COG0204	Acyl-transferase
A4U85_14525	COG2894	cell division
A4U85_14540	COG1280	lysine exporter protein (LysE YggA)
A4U85_14545	COG1674	ftsk spoiiie
A4U85_14550	COG0492	ferredoxin-NADP+ reductase activity
A4U85_14555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A4U85_14565	COG0456	acetyltransferase
A4U85_14625	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A4U85_14625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A4U85_14645	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_14665	COG0473	3-isopropylmalate dehydrogenase activity
A4U85_14670	COG0583	DNA-binding transcription factor activity
A4U85_14690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A4U85_14715	COG0564	pseudouridine synthase activity
A4U85_14725	COG0358	DNA primase activity
A4U85_14740	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A4U85_14770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A4U85_14800	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A4U85_14810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A4U85_14810	COG0351	phosphomethylpyrimidine kinase
A4U85_14810	COG0352	thiamine-phosphate diphosphorylase activity
A4U85_14815	COG1652	LysM domain
A4U85_14840	COG1399	metal-binding, possibly nucleic acid-binding protein
A4U85_14845	COG3101	peptidyl-lysine hydroxylation
A4U85_14850	COG0009	L-threonylcarbamoyladenylate synthase
A4U85_14855	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A4U85_14860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A4U85_14875	COG4106	trans-aconitate 2-methyltransferase activity
A4U85_14890	COG2226	methyltransferase
A4U85_14890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A4U85_14890	COG0596	Alpha beta hydrolase
A4U85_14895	COG1877	trehalose-phosphatase activity
A4U85_14900	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A4U85_14905	COG2223	nitrite transmembrane transporter activity
A4U85_14925	COG1196	nuclear chromosome segregation
A4U85_14935	COG0730	response to heat
A4U85_14950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A4U85_14960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A4U85_15005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A4U85_15010	COG0489	protein tyrosine kinase activity
A4U85_15020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A4U85_15020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A4U85_15050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A4U85_15055	COG2081	HI0933 family
A4U85_15065	COG0668	transmembrane transport
A4U85_15085	COG0583	DNA-binding transcription factor activity
A4U85_15105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A4U85_15110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A4U85_15140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A4U85_15175	COG2205	protein histidine kinase activity
A4U85_15180	COG0745	RESPONSE REGULATOR receiver
A4U85_15200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A4U85_15260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A4U85_15265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
A4U85_15275	COG0583	DNA-binding transcription factor activity
A4U85_15285	COG0583	DNA-binding transcription factor activity
A4U85_15300	COG0583	DNA-binding transcription factor activity
A4U85_15305	COG1053	succinate dehydrogenase
A4U85_15320	COG1309	transcriptional regulator
A4U85_15325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A4U85_15330	COG2814	Major facilitator Superfamily
A4U85_15335	COG1960	acyl-CoA dehydrogenase activity
A4U85_15340	COG0583	DNA-binding transcription factor activity
A4U85_15345	COG1063	alcohol dehydrogenase
A4U85_15375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A4U85_15380	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A4U85_15385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A4U85_15405	COG2132	Multicopper oxidase
A4U85_15415	COG0561	phosphatase activity
A4U85_15420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A4U85_15430	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A4U85_15445	COG1214	PFAM Peptidase M22, glycoprotease
A4U85_15495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A4U85_15505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A4U85_15510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A4U85_15515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A4U85_15575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A4U85_15585	COG1846	Transcriptional regulator
A4U85_15590	COG1764	response to oxidative stress
A4U85_15615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4U85_15615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4U85_15630	COG0037	tRNA processing
A4U85_15640	COG0248	Ppx GppA phosphatase
A4U85_15665	COG0072	phenylalanine-tRNA ligase activity
A4U85_15690	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A4U85_15705	COG1238	metal cluster binding
A4U85_15710	COG0625	glutathione transferase activity
A4U85_15725	COG0318	PFAM AMP-dependent synthetase and ligase
A4U85_15730	COG3028	Belongs to the UPF0307 family
A4U85_15735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4U85_15755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4U85_15760	COG0617	tRNA 3'-terminal CCA addition
A4U85_15765	COG1555	photosystem II stabilization
A4U85_15770	COG3956	TIGRFAM MazG family protein
A4U85_15780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A4U85_15800	COG5002	protein histidine kinase activity
A4U85_15800	COG2205	protein histidine kinase activity
A4U85_15800	COG0784	Response regulator, receiver
A4U85_15805	COG1024	Enoyl-CoA hydratase
A4U85_15810	COG2084	Dehydrogenase
A4U85_15815	COG3622	Belongs to the hyi family
A4U85_15830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A4U85_15835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A4U85_15840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
A4U85_15845	COG0697	spore germination
A4U85_15855	COG2814	Major facilitator Superfamily
A4U85_15860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A4U85_15870	COG0583	DNA-binding transcription factor activity
A4U85_15875	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A4U85_15890	COG0084	hydrolase, TatD family'
A4U85_15905	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A4U85_15935	COG0440	acetolactate synthase activity
A4U85_15940	COG0028	Belongs to the TPP enzyme family
A4U85_15965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4U85_15970	COG1136	(ABC) transporter
A4U85_15970	COG0577	efflux transmembrane transporter activity
A4U85_15975	COG1538	Outer membrane efflux protein
A4U85_15990	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A4U85_15995	COG1162	GTPase activity
A4U85_16005	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A4U85_16045	COG1426	Protein conserved in bacteria
A4U85_16080	COG0793	Belongs to the peptidase S41A family
A4U85_16095	COG2267	carboxylic ester hydrolase activity
A4U85_16105	COG1012	belongs to the aldehyde dehydrogenase family
A4U85_16110	COG3265	gluconokinase activity
A4U85_16120	COG0800	Aldolase
A4U85_16130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A4U85_16135	COG0857	belongs to the CobB CobQ family
A4U85_16135	COG0280	phosphate acetyltransferase
A4U85_16140	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A4U85_16140	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A4U85_16160	COG0740	serine-type endopeptidase activity
A4U85_16170	COG4774	siderophore transport
A4U85_16180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A4U85_16190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A4U85_16190	COG2813	Specifically methylates the guanine in position
A4U85_16335	COG0788	formyltetrahydrofolate deformylase activity
A4U85_16350	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A4U85_16355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A4U85_16360	COG4651	solute:proton antiporter activity
A4U85_16360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A4U85_16380	COG0724	RNA recognition motif
A4U85_16385	COG0210	DNA helicase
A4U85_16410	COG1733	regulation of RNA biosynthetic process
A4U85_16430	COG1280	lysine exporter protein (LysE YggA)
A4U85_16435	COG1560	Kdo2-lipid A biosynthetic process
A4U85_16445	COG1301	dicarboxylic acid transport
A4U85_16500	COG0473	3-isopropylmalate dehydrogenase activity
A4U85_16565	COG0583	DNA-binding transcription factor activity
A4U85_16575	COG0625	glutathione transferase activity
A4U85_16580	COG2378	regulation of single-species biofilm formation
A4U85_16585	COG0546	phosphoglycolate phosphatase activity
A4U85_16595	COG1530	ribonuclease E activity
A4U85_16615	COG0583	DNA-binding transcription factor activity
A4U85_16620	COG4221	oxidoreductase activity
A4U85_16625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A4U85_16635	COG0534	Mate efflux family protein
A4U85_16650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A4U85_16685	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A4U85_16690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A4U85_16705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A4U85_16715	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A4U85_16715	COG0644	oxidoreductase
A4U85_16720	COG0425	Belongs to the sulfur carrier protein TusA family
A4U85_16725	COG4535	Mg2 and Co2 transporter CorC
A4U85_16735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A4U85_16755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A4U85_16760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A4U85_16760	COG0475	glutathione-regulated potassium exporter activity
A4U85_16775	COG0484	heat shock protein binding
A4U85_16780	COG0789	Transcriptional regulator
A4U85_16785	COG0598	Magnesium transport protein CorA
A4U85_16805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A4U85_16810	COG1074	ATP-dependent DNA helicase activity
A4U85_16815	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A4U85_16835	COG2226	methyltransferase
A4U85_16850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A4U85_16855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A4U85_16870	COG2111	Na H antiporter
A4U85_16870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A4U85_16875	COG1006	Multisubunit Na H antiporter MnhC subunit
A4U85_16880	COG0651	ATP synthesis coupled electron transport
A4U85_16890	COG2212	antiporter activity
A4U85_16910	COG0195	Participates in both transcription termination and antitermination
A4U85_16955	COG0237	dephospho-CoA kinase activity
A4U85_16965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A4U85_16980	COG0497	DNA recombination
A4U85_16990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A4U85_17020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A4U85_17020	COG2169	Transcriptional regulator
A4U85_17025	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A4U85_17085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A4U85_17100	COG0326	Molecular chaperone. Has ATPase activity
A4U85_17115	COG2056	Na+-H+ antiporter family
A4U85_17215	COG0546	phosphoglycolate phosphatase activity
A4U85_17220	COG1716	ATPase activity
A4U85_17265	COG0181	hydroxymethylbilane synthase activity
A4U85_17275	COG3275	phosphorelay sensor kinase activity
A4U85_17295	COG1538	Outer membrane efflux protein
A4U85_17300	COG0697	spore germination
A4U85_17325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A4U85_17330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A4U85_17335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A4U85_17340	COG0772	Belongs to the SEDS family
A4U85_17365	COG4974	Belongs to the 'phage' integrase family
A4U85_17370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A4U85_17380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A4U85_17390	COG2197	response regulator
A4U85_17405	COG0793	Belongs to the peptidase S41A family
A4U85_17410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A4U85_17415	COG0795	lipopolysaccharide-transporting ATPase activity
A4U85_17455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A4U85_17455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A4U85_17465	COG0004	ammonium transporteR
A4U85_17470	COG0347	Belongs to the P(II) protein family
A4U85_17480	COG0606	chelatase, subunit chli
A4U85_17485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4U85_17495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A4U85_17510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A4U85_17525	COG0318	PFAM AMP-dependent synthetase and ligase
A4U85_17535	COG0477	Major facilitator Superfamily
A4U85_17540	COG2860	membrane
A4U85_17550	COG1253	flavin adenine dinucleotide binding
A4U85_17560	COG2814	Major facilitator Superfamily
A4U85_17570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A4U85_17605	COG0655	NAD(P)H dehydrogenase (quinone) activity
A4U85_17615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A4U85_17650	COG1309	transcriptional regulator
A4U85_17685	COG0758	DNA mediated transformation
A4U85_17695	COG0697	spore germination
A4U85_17700	COG1309	transcriptional regulator
A4U85_17715	COG0386	Belongs to the glutathione peroxidase family
A4U85_17780	COG1121	(ABC) transporter
A4U85_17785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A4U85_17790	COG1280	lysine exporter protein (LysE YggA)
A4U85_17795	COG2837	iron assimilation
A4U85_17800	COG0281	malic enzyme
A4U85_17845	COG0519	Catalyzes the synthesis of GMP from XMP
A4U85_17845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A4U85_17850	COG4399	Belongs to the UPF0754 family
A4U85_17855	COG2259	Doxx family
A4U85_17860	COG0586	Pfam SNARE associated Golgi protein
A4U85_17875	COG1192	Involved in chromosome partitioning
A4U85_17885	COG0271	Belongs to the BolA IbaG family
A4U85_17905	COG2267	carboxylic ester hydrolase activity
A4U85_17925	COG3321	synthase
A4U85_17925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A4U85_17925	COG0318	PFAM AMP-dependent synthetase and ligase
A4U85_17925	COG0300	oxidoreductase activity
A4U85_17925	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_17930	COG1960	acyl-CoA dehydrogenase activity
A4U85_17940	COG2197	response regulator
A4U85_17950	COG3916	Acyl-homoserine-lactone synthase
A4U85_17955	COG0477	Major facilitator Superfamily
A4U85_17960	COG1024	Enoyl-CoA hydratase
A4U85_17965	COG1024	Enoyl-CoA hydratase
A4U85_17970	COG1960	acyl-CoA dehydrogenase activity
A4U85_17975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A4U85_17995	COG1113	amino acid transport
A4U85_18000	COG1113	amino acid transport
A4U85_18005	COG0251	oxidation-reduction process
A4U85_18020	COG1522	sequence-specific DNA binding
A4U85_18045	COG0564	pseudouridine synthase activity
A4U85_18120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A4U85_18135	COG1802	Transcriptional regulator
A4U85_18140	COG1448	Aminotransferase
A4U85_18145	COG0277	FAD linked oxidase domain protein
A4U85_18155	COG2186	Transcriptional regulator
A4U85_18165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4U85_18170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A4U85_18185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A4U85_18190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A4U85_18215	COG0438	transferase activity, transferring glycosyl groups
A4U85_18245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A4U85_18250	COG1596	polysaccharide export
A4U85_18275	COG0728	peptidoglycan biosynthetic process
A4U85_18280	COG3023	N-Acetylmuramoyl-L-alanine amidase
A4U85_18395	COG2184	nucleotidyltransferase activity
A4U85_18415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4U85_18450	COG0798	PFAM Bile acid sodium symporter
A4U85_18485	COG4691	Plasmid stability protein
A4U85_18575	COG0546	phosphoglycolate phosphatase activity
A4U85_18580	COG1028	Short-chain dehydrogenase reductase Sdr
A4U85_18600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A4U85_18605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A4U85_18610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A4U85_18615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A4U85_18620	COG1116	anion transmembrane transporter activity
A4U85_18625	COG1309	transcriptional regulator
A4U85_18630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A4U85_18640	COG0196	riboflavin kinase activity
A4U85_18645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A4U85_18655	COG1047	Peptidyl-prolyl cis-trans
A4U85_18695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A4U85_18720	COG0583	DNA-binding transcription factor activity
A4U85_18750	COG2951	lytic endotransglycosylase activity
A4U85_18755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A4U85_18770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A4U85_18780	COG0671	phosphoesterase, PA-phosphatase related
A4U85_18785	COG0861	Integral membrane protein TerC family
A4U85_18795	COG0754	glutathionylspermidine amidase activity
A4U85_18805	COG0402	S-adenosylhomocysteine deaminase activity
A4U85_18825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A4U85_18830	COG1230	cation diffusion facilitator family transporter
A4U85_18845	COG0706	membrane insertase activity
A4U85_18860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A4U85_18870	COG1764	response to oxidative stress
A4U85_18875	COG1846	Transcriptional regulator
A4U85_18910	COG4683	PFAM Phage derived protein Gp49-like (DUF891)