locus-tag	class	description
NQU59_00045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQU59_00055	COG1764	response to oxidative stress
NQU59_00080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQU59_00080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQU59_00095	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NQU59_00095	COG2755	lipolytic protein G-D-S-L family
NQU59_00110	COG0037	tRNA processing
NQU59_00120	COG0248	Ppx GppA phosphatase
NQU59_00145	COG0072	phenylalanine-tRNA ligase activity
NQU59_00195	COG1238	metal cluster binding
NQU59_00210	COG0625	glutathione transferase activity
NQU59_00230	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_00235	COG3028	Belongs to the UPF0307 family
NQU59_00260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NQU59_00265	COG0617	tRNA 3'-terminal CCA addition
NQU59_00270	COG1555	photosystem II stabilization
NQU59_00275	COG3956	TIGRFAM MazG family protein
NQU59_00285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQU59_00305	COG0784	Response regulator, receiver
NQU59_00305	COG2205	protein histidine kinase activity
NQU59_00305	COG5002	protein histidine kinase activity
NQU59_00315	COG2084	Dehydrogenase
NQU59_00320	COG3622	Belongs to the hyi family
NQU59_00330	COG1051	belongs to the nudix hydrolase family
NQU59_00365	COG2814	Major facilitator Superfamily
NQU59_00370	COG1002	Type II restriction enzyme, methylase subunits
NQU59_00380	COG1061	Type III restriction enzyme res subunit
NQU59_00390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NQU59_00455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NQU59_00475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NQU59_00490	COG0084	hydrolase, TatD family'
NQU59_00495	COG0726	polysaccharide deacetylase
NQU59_00505	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NQU59_00520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQU59_00525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NQU59_00575	COG1476	TRANSCRIPTIONal
NQU59_00600	COG0440	acetolactate synthase activity
NQU59_00605	COG0028	Belongs to the TPP enzyme family
NQU59_00630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQU59_00635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQU59_00640	COG0577	efflux transmembrane transporter activity
NQU59_00640	COG1136	(ABC) transporter
NQU59_00645	COG1538	Outer membrane efflux protein
NQU59_00675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NQU59_00680	COG1162	GTPase activity
NQU59_00690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NQU59_00715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NQU59_00725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQU59_00735	COG3781	membrane
NQU59_00740	COG0667	Aldo Keto reductase
NQU59_00745	COG0583	DNA-binding transcription factor activity
NQU59_00780	COG1666	GTP binding
NQU59_00790	COG1956	GAF domain-containing protein
NQU59_00795	COG1607	acyl-coa hydrolase
NQU59_00850	COG1183	phosphatidylcholine synthase activity
NQU59_00855	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NQU59_00885	COG1196	nuclear chromosome segregation
NQU59_00885	COG0741	lytic transglycosylase activity
NQU59_00885	COG0739	heme binding
NQU59_00895	COG1702	phosphate starvation-inducible protein PhoH
NQU59_00930	COG3878	Protein conserved in bacteria
NQU59_00935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NQU59_00975	COG0788	formyltetrahydrofolate deformylase activity
NQU59_01000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NQU59_01000	COG4651	solute:proton antiporter activity
NQU59_01020	COG0724	RNA recognition motif
NQU59_01025	COG0210	DNA helicase
NQU59_01050	COG2900	Belongs to the SlyX family
NQU59_01055	COG0488	(ABC) transporter
NQU59_01060	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NQU59_01065	COG1560	Kdo2-lipid A biosynthetic process
NQU59_01145	COG0473	3-isopropylmalate dehydrogenase activity
NQU59_01160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQU59_01170	COG0583	DNA-binding transcription factor activity
NQU59_01190	COG0494	nUDIX hydrolase
NQU59_01205	COG0753	catalase activity
NQU59_01225	COG0583	DNA-binding transcription factor activity
NQU59_01230	COG0625	glutathione transferase activity
NQU59_01240	COG0546	phosphoglycolate phosphatase activity
NQU59_01250	COG1530	ribonuclease E activity
NQU59_01255	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_01270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQU59_01280	COG0534	Mate efflux family protein
NQU59_01285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NQU59_01315	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_01320	COG1309	transcriptional regulator
NQU59_01325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQU59_01340	COG0493	'glutamate synthase
NQU59_01340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQU59_01350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NQU59_01390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQU59_01405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQU59_01415	COG0644	oxidoreductase
NQU59_01415	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NQU59_01435	COG0425	Belongs to the sulfur carrier protein TusA family
NQU59_01440	COG4535	Mg2 and Co2 transporter CorC
NQU59_01445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NQU59_01450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQU59_01470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQU59_01480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NQU59_01495	COG0789	Transcriptional regulator
NQU59_01500	COG0598	Magnesium transport protein CorA
NQU59_01505	COG1301	dicarboxylic acid transport
NQU59_01510	COG1185	polyribonucleotide nucleotidyltransferase activity
NQU59_01515	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NQU59_01520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQU59_01525	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQU59_01530	COG1074	ATP-dependent DNA helicase activity
NQU59_01535	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NQU59_01560	COG2226	methyltransferase
NQU59_01570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NQU59_01575	COG3038	cytochrome b561
NQU59_01595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NQU59_01610	COG2111	Na H antiporter
NQU59_01610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NQU59_01615	COG1006	Multisubunit Na H antiporter MnhC subunit
NQU59_01620	COG0651	ATP synthesis coupled electron transport
NQU59_01625	COG1863	multisubunit Na H antiporter MnhE subunit
NQU59_01630	COG2212	antiporter activity
NQU59_01635	COG1320	monovalent cation:proton antiporter activity
NQU59_01640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NQU59_01650	COG0195	Participates in both transcription termination and antitermination
NQU59_01675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NQU59_01700	COG0237	dephospho-CoA kinase activity
NQU59_01710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQU59_01720	COG0497	DNA recombination
NQU59_01730	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NQU59_01760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NQU59_01805	COG1132	(ABC) transporter
NQU59_01815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NQU59_01835	COG0326	Molecular chaperone. Has ATPase activity
NQU59_01850	COG2056	Na+-H+ antiporter family
NQU59_01885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NQU59_01895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NQU59_01945	COG0546	phosphoglycolate phosphatase activity
NQU59_01950	COG1716	ATPase activity
NQU59_01995	COG0181	hydroxymethylbilane synthase activity
NQU59_02005	COG3275	phosphorelay sensor kinase activity
NQU59_02030	COG0494	nUDIX hydrolase
NQU59_02040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NQU59_02045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQU59_02050	COG0772	Belongs to the SEDS family
NQU59_02075	COG4974	Belongs to the 'phage' integrase family
NQU59_02080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NQU59_02090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NQU59_02100	COG2197	response regulator
NQU59_02115	COG0793	Belongs to the peptidase S41A family
NQU59_02120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NQU59_02125	COG0795	lipopolysaccharide-transporting ATPase activity
NQU59_02130	COG0795	lipopolysaccharide-transporting ATPase activity
NQU59_02165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NQU59_02165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NQU59_02175	COG0004	ammonium transporteR
NQU59_02180	COG0347	Belongs to the P(II) protein family
NQU59_02215	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NQU59_02230	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_02260	COG2860	membrane
NQU59_02270	COG1253	flavin adenine dinucleotide binding
NQU59_02285	COG2814	Major facilitator Superfamily
NQU59_02300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQU59_02305	COG0745	RESPONSE REGULATOR receiver
NQU59_02310	COG2205	protein histidine kinase activity
NQU59_02340	COG2814	Major facilitator Superfamily
NQU59_02370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NQU59_02405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NQU59_02425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQU59_02430	COG3162	membrane
NQU59_02435	COG2205	protein histidine kinase activity
NQU59_02435	COG0784	Response regulator, receiver
NQU59_02465	COG1652	LysM domain
NQU59_02470	COG0758	DNA mediated transformation
NQU59_02480	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQU59_02485	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQU59_02490	COG3845	ABC transporter
NQU59_02535	COG1309	transcriptional regulator
NQU59_02540	COG2814	Major facilitator Superfamily
NQU59_02555	COG0386	Belongs to the glutathione peroxidase family
NQU59_02565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NQU59_02570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NQU59_02580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NQU59_02620	COG1121	(ABC) transporter
NQU59_02625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQU59_02630	COG1280	lysine exporter protein (LysE YggA)
NQU59_02635	COG2837	iron assimilation
NQU59_02685	COG2271	Major facilitator Superfamily
NQU59_02710	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_02715	COG0583	DNA-binding transcription factor activity
NQU59_02725	COG0519	Catalyzes the synthesis of GMP from XMP
NQU59_02725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NQU59_02730	COG4399	Belongs to the UPF0754 family
NQU59_02735	COG3111	PFAM Bacterial OB fold (BOF) protein
NQU59_02740	COG2259	Doxx family
NQU59_02745	COG0586	Pfam SNARE associated Golgi protein
NQU59_02760	COG1192	Involved in chromosome partitioning
NQU59_02770	COG0271	Belongs to the BolA IbaG family
NQU59_02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQU59_02795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQU59_02800	COG1113	amino acid transport
NQU59_02805	COG0697	spore germination
NQU59_02810	COG0477	Major facilitator Superfamily
NQU59_02820	COG1024	Enoyl-CoA hydratase
NQU59_02825	COG1960	acyl-CoA dehydrogenase activity
NQU59_02830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQU59_02850	COG1113	amino acid transport
NQU59_02855	COG0251	oxidation-reduction process
NQU59_02880	COG0456	acetyltransferase
NQU59_02885	COG0564	pseudouridine synthase activity
NQU59_02925	COG1487	ribonuclease activity
NQU59_02930	COG4456	Virulence-associated protein
NQU59_02935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQU59_02950	COG1802	Transcriptional regulator
NQU59_02955	COG1448	Aminotransferase
NQU59_02960	COG0277	FAD linked oxidase domain protein
NQU59_02970	COG2186	Transcriptional regulator
NQU59_02980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQU59_02985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQU59_03000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NQU59_03005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQU59_03030	COG1215	transferase activity, transferring glycosyl groups
NQU59_03050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NQU59_03060	COG1596	polysaccharide export
NQU59_03085	COG0728	peptidoglycan biosynthetic process
NQU59_03090	COG3023	N-Acetylmuramoyl-L-alanine amidase
NQU59_03145	COG0546	phosphoglycolate phosphatase activity
NQU59_03150	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_03160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NQU59_03160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NQU59_03165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQU59_03170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQU59_03175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQU59_03180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_03185	COG1116	anion transmembrane transporter activity
NQU59_03190	COG1309	transcriptional regulator
NQU59_03195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQU59_03205	COG0196	riboflavin kinase activity
NQU59_03210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NQU59_03220	COG1047	Peptidyl-prolyl cis-trans
NQU59_03260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQU59_03265	COG0657	acetylesterase activity
NQU59_03280	COG0583	DNA-binding transcription factor activity
NQU59_03290	COG0443	Heat shock 70 kDa protein
NQU59_03295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NQU59_03320	COG2951	lytic endotransglycosylase activity
NQU59_03325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NQU59_03345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NQU59_03365	COG1960	acyl-CoA dehydrogenase activity
NQU59_03370	COG0583	DNA-binding transcription factor activity
NQU59_03380	COG0861	Integral membrane protein TerC family
NQU59_03385	COG0402	S-adenosylhomocysteine deaminase activity
NQU59_03415	COG0706	membrane insertase activity
NQU59_03440	COG0592	DNA-directed DNA polymerase activity
NQU59_03450	COG0187	DNA topoisomerase II activity
NQU59_03455	COG0586	Pfam SNARE associated Golgi protein
NQU59_03460	COG0488	(ABC) transporter
NQU59_03490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NQU59_03495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NQU59_03545	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_03550	COG0733	neurotransmitter:sodium symporter activity
NQU59_03585	COG0583	DNA-binding transcription factor activity
NQU59_03595	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_03600	COG2233	PERMEase
NQU59_03610	COG1309	transcriptional regulator
NQU59_03615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQU59_03645	COG2814	Major facilitator Superfamily
NQU59_03650	COG0656	L-ascorbic acid biosynthetic process
NQU59_03655	COG0583	DNA-binding transcription factor activity
NQU59_03665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQU59_03675	COG1064	alcohol dehydrogenase
NQU59_03680	COG2818	Glycosylase
NQU59_03695	COG1194	a g-specific adenine glycosylase
NQU59_03705	COG5487	UPF0391 membrane protein
NQU59_03710	COG2983	Belongs to the UPF0260 family
NQU59_03715	COG2133	pyrroloquinoline quinone binding
NQU59_03725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NQU59_03750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQU59_03760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQU59_03765	COG1335	isochorismatase
NQU59_03770	COG1522	sequence-specific DNA binding
NQU59_03780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQU59_03790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NQU59_03795	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NQU59_03820	COG3830	Belongs to the UPF0237 family
NQU59_03820	COG0560	Phosphoserine phosphatase
NQU59_03840	COG0753	catalase activity
NQU59_03880	COG0583	DNA-binding transcription factor activity
NQU59_03890	COG0583	DNA-binding transcription factor activity
NQU59_03925	COG0534	Mate efflux family protein
NQU59_03930	COG0436	Aminotransferase
NQU59_03935	COG2733	membrane
NQU59_03950	COG2918	glutathione biosynthetic process
NQU59_03965	COG1388	LysM domain
NQU59_03965	COG5632	N-Acetylmuramoyl-L-alanine amidase
NQU59_03965	COG3409	Peptidoglycan-binding domain 1 protein
NQU59_04000	COG3150	esterase
NQU59_04055	COG0666	response to abiotic stimulus
NQU59_04055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQU59_04090	COG1393	Belongs to the ArsC family
NQU59_04095	COG0708	Exodeoxyribonuclease III
NQU59_04120	COG0300	oxidoreductase activity
NQU59_04145	COG1846	Transcriptional regulator
NQU59_04150	COG0386	Belongs to the glutathione peroxidase family
NQU59_04155	COG0189	ligase activity
NQU59_04175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NQU59_04220	COG2119	membrane
NQU59_04225	COG0426	domain, Protein
NQU59_04225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQU59_04245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NQU59_04270	COG1902	pentaerythritol trinitrate reductase activity
NQU59_04280	COG1519	Transferase
NQU59_04290	COG0668	transmembrane transport
NQU59_04300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQU59_04305	COG1335	isochorismatase
NQU59_04310	COG1522	sequence-specific DNA binding
NQU59_04370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NQU59_04370	COG0352	thiamine-phosphate diphosphorylase activity
NQU59_04370	COG0351	phosphomethylpyrimidine kinase
NQU59_04380	COG2814	Major facilitator Superfamily
NQU59_04400	COG1335	isochorismatase
NQU59_04410	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NQU59_04510	COG2205	protein histidine kinase activity
NQU59_04525	COG0326	Molecular chaperone. Has ATPase activity
NQU59_04555	COG3158	transport of potassium into the cell
NQU59_04585	COG0107	imidazoleglycerol-phosphate synthase activity
NQU59_04645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NQU59_04670	COG2226	methyltransferase
NQU59_04675	COG0427	acetyl-CoA hydrolase
NQU59_04730	COG0583	DNA-binding transcription factor activity
NQU59_04735	COG2851	Citrate transporter
NQU59_04745	COG0477	Major facilitator Superfamily
NQU59_04750	COG0789	Transcriptional regulator
NQU59_04755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQU59_04755	COG3320	Male sterility
NQU59_04760	COG4221	oxidoreductase activity
NQU59_04770	COG0488	(ABC) transporter
NQU59_04835	COG0833	amino acid
NQU59_04860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NQU59_04880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NQU59_04885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQU59_04895	COG2226	methyltransferase
NQU59_04945	COG0067	glutamate synthase
NQU59_04945	COG0070	glutamate synthase
NQU59_04945	COG0069	glutamate synthase activity
NQU59_04950	COG0493	'glutamate synthase
NQU59_04965	COG1704	LemA family
NQU59_04970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NQU59_05015	COG1132	(ABC) transporter
NQU59_05060	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NQU59_05065	COG3307	-O-antigen
NQU59_05085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQU59_05095	COG0194	GDP metabolic process
NQU59_05100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQU59_05170	COG0228	four-way junction DNA binding
NQU59_05175	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NQU59_05185	COG0335	large ribosomal subunit rRNA binding
NQU59_05190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NQU59_05210	COG5006	permease, DMT superfamily
NQU59_05215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQU59_05220	COG0277	FAD linked oxidase domain protein
NQU59_05250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NQU59_05255	COG2249	NAD(P)H dehydrogenase (quinone) activity
NQU59_05275	COG1289	transmembrane transporter activity
NQU59_05285	COG0628	permease
NQU59_05290	COG1192	Involved in chromosome partitioning
NQU59_05300	COG2226	methyltransferase
NQU59_05335	COG1404	Belongs to the peptidase S8 family
NQU59_05390	COG0517	IMP dehydrogenase activity
NQU59_05395	COG1983	PspC domain protein
NQU59_05405	COG1960	acyl-CoA dehydrogenase activity
NQU59_05430	COG0408	coproporphyrinogen oxidase activity
NQU59_05455	COG1127	ABC transporter
NQU59_05460	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQU59_05465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NQU59_05470	COG2854	intermembrane phospholipid transfer
NQU59_05480	COG0598	Magnesium transport protein CorA
NQU59_05490	COG0494	nUDIX hydrolase
NQU59_05495	COG1040	competence protein
NQU59_05500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NQU59_05515	COG2937	Belongs to the GPAT DAPAT family
NQU59_05520	COG1946	Acyl-CoA thioesterase
NQU59_05525	COG1301	dicarboxylic acid transport
NQU59_05540	COG1959	2 iron, 2 sulfur cluster binding
NQU59_05550	COG0433	COG0433 Predicted ATPase
NQU59_05570	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQU59_05590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NQU59_05615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQU59_05640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQU59_05655	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQU59_05665	COG0200	Binds to the 23S rRNA
NQU59_05690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQU59_05720	COG1960	acyl-CoA dehydrogenase activity
NQU59_05725	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NQU59_05760	COG0697	spore germination
NQU59_05785	COG0339	signal peptide processing
NQU59_05795	COG0557	exoribonuclease II activity
NQU59_05835	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQU59_05840	COG2207	Transcriptional regulator
NQU59_05850	COG1295	ribonuclease BN
NQU59_05875	COG1785	Belongs to the alkaline phosphatase family
NQU59_05940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQU59_05940	COG2813	Specifically methylates the guanine in position
NQU59_05950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQU59_05960	COG4774	siderophore transport
NQU59_05965	COG4774	siderophore transport
NQU59_05975	COG0740	serine-type endopeptidase activity
NQU59_05995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NQU59_05995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NQU59_06015	COG0280	phosphate acetyltransferase
NQU59_06015	COG0857	belongs to the CobB CobQ family
NQU59_06020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NQU59_06045	COG0793	Belongs to the peptidase S41A family
NQU59_06060	COG1346	cytolysis
NQU59_06070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQU59_06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQU59_06090	COG1408	metallophosphoesterase
NQU59_06100	COG2199	diguanylate cyclase activity
NQU59_06150	COG1960	acyl-CoA dehydrogenase activity
NQU59_06155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NQU59_06160	COG1309	transcriptional regulator
NQU59_06175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQU59_06180	COG1960	acyl-CoA dehydrogenase activity
NQU59_06190	COG4770	biotin carboxylase activity
NQU59_06230	COG2969	positive regulation of protein catabolic process
NQU59_06235	COG0625	glutathione transferase activity
NQU59_06245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NQU59_06250	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NQU59_06260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NQU59_06265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQU59_06270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NQU59_06340	COG1953	Uracil, thiamine, allantoin
NQU59_06350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQU59_06360	COG1862	Preprotein translocase
NQU59_06425	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NQU59_06475	COG3306	glycosyltransferase involved in LPS biosynthesis
NQU59_06495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQU59_06545	COG1960	acyl-CoA dehydrogenase activity
NQU59_06550	COG1960	acyl-CoA dehydrogenase activity
NQU59_06560	COG2205	protein histidine kinase activity
NQU59_06565	COG0745	RESPONSE REGULATOR receiver
NQU59_06575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NQU59_06595	COG2096	Adenosyltransferase
NQU59_06600	COG4206	TonB-dependent receptor
NQU59_06660	COG0285	dihydrofolate synthase activity
NQU59_06680	COG0450	alkyl hydroperoxide reductase
NQU59_06700	COG0477	Major facilitator Superfamily
NQU59_06705	COG1272	protein, Hemolysin III
NQU59_06750	COG0183	Belongs to the thiolase family
NQU59_06770	COG2207	Transcriptional regulator
NQU59_06775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NQU59_06790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQU59_06805	COG0183	Belongs to the thiolase family
NQU59_06830	COG1690	Belongs to the RtcB family
NQU59_06835	COG0833	amino acid
NQU59_06845	COG2233	PERMEase
NQU59_06850	COG1217	gtp-binding protein TYPA
NQU59_06875	COG4772	TonB-dependent receptor
NQU59_06885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NQU59_06900	COG0354	folic acid binding
NQU59_06915	COG3189	MarR family transcriptional regulator
NQU59_06920	COG2824	Alkylphosphonate utilization operon protein PhnA
NQU59_06925	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_06930	COG3422	double-strand break repair
NQU59_06960	COG0840	transmembrane signaling receptor activity
NQU59_06965	COG0643	Histidine kinase
NQU59_06965	COG2198	Histidine kinase
NQU59_06965	COG0643	Histidine kinase
NQU59_06965	COG2198	Histidine kinase
NQU59_06990	COG2832	Protein of unknown function (DUF454)
NQU59_07075	COG1289	transmembrane transporter activity
NQU59_07080	COG2814	Major facilitator Superfamily
NQU59_07095	COG0786	glutamate:sodium symporter activity
NQU59_07100	COG1115	amino acid carrier protein
NQU59_07105	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQU59_07110	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NQU59_07185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQU59_07195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQU59_07200	COG1077	Cell shape determining protein MreB Mrl
NQU59_07205	COG1792	Involved in formation and maintenance of cell shape
NQU59_07215	COG0424	maF-like protein
NQU59_07220	COG1530	ribonuclease E activity
NQU59_07230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQU59_07240	COG0560	Phosphoserine phosphatase
NQU59_07255	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NQU59_07260	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NQU59_07265	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NQU59_07270	COG2205	protein histidine kinase activity
NQU59_07275	COG0745	RESPONSE REGULATOR receiver
NQU59_07280	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_07310	COG2851	Citrate transporter
NQU59_07320	COG0671	phosphoesterase, PA-phosphatase related
NQU59_07325	COG0174	glutamine synthetase
NQU59_07335	COG1113	amino acid transport
NQU59_07345	COG0142	geranyltranstransferase activity
NQU59_07350	COG2315	Protein conserved in bacteria
NQU59_07365	COG1752	Esterase of the alpha-beta hydrolase superfamily
NQU59_07385	COG2194	sulfuric ester hydrolase activity
NQU59_07390	COG0745	RESPONSE REGULATOR receiver
NQU59_07395	COG0642	Histidine kinase
NQU59_07410	COG1126	abc transporter atp-binding protein
NQU59_07415	COG0765	amino acid transport
NQU59_07420	COG0765	amino acid transport
NQU59_07430	COG0004	ammonium transporteR
NQU59_07435	COG2031	fatty acid transporter
NQU59_07450	COG0583	DNA-binding transcription factor activity
NQU59_07460	COG2610	gluconate transmembrane transporter activity
NQU59_07465	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_07475	COG2852	Protein conserved in bacteria
NQU59_07480	COG0525	valine-tRNA ligase activity
NQU59_07495	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_07505	COG0393	Putative heavy-metal-binding
NQU59_07510	COG0393	Putative heavy-metal-binding
NQU59_07515	COG1538	Outer membrane efflux protein
NQU59_07525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQU59_07560	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NQU59_07575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NQU59_07575	COG1648	precorrin-2 dehydrogenase activity
NQU59_07580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NQU59_07590	COG1733	regulation of RNA biosynthetic process
NQU59_07600	COG0531	amino acid
NQU59_07615	COG0321	lipoyl(octanoyl) transferase activity
NQU59_07620	COG2921	Belongs to the UPF0250 family
NQU59_07640	COG1280	lysine exporter protein (LysE YggA)
NQU59_07645	COG0583	DNA-binding transcription factor activity
NQU59_07650	COG1054	Belongs to the UPF0176 family
NQU59_07680	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NQU59_07685	COG1053	succinate dehydrogenase
NQU59_07690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NQU59_07710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQU59_07730	COG2268	Band 7 protein
NQU59_07735	COG1585	Membrane protein implicated in regulation of membrane protease activity
NQU59_07745	COG2354	Protein conserved in bacteria
NQU59_07750	COG2321	neutral zinc metallopeptidase
NQU59_07765	COG3328	transposase activity
NQU59_07790	COG0589	response to stress
NQU59_07800	COG0251	oxidation-reduction process
NQU59_07805	COG1309	transcriptional regulator
NQU59_07815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NQU59_07820	COG0505	Belongs to the CarA family
NQU59_07845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQU59_07850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NQU59_07860	COG2304	oxidoreductase activity
NQU59_07885	COG0584	glycerophosphoryl diester phosphodiesterase
NQU59_07900	COG2239	Acts as a magnesium transporter
NQU59_07910	COG0501	Belongs to the peptidase M48B family
NQU59_07915	COG0741	lytic transglycosylase activity
NQU59_07935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQU59_07945	COG0582	viral genome integration into host DNA
NQU59_07995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NQU59_08025	COG0583	DNA-binding transcription factor activity
NQU59_08045	COG1607	acyl-coa hydrolase
NQU59_08055	COG0523	cobalamin synthesis protein
NQU59_08060	COG4681	YaeQ
NQU59_08075	COG0726	polysaccharide deacetylase
NQU59_08075	COG1649	PFAM Uncharacterised BCR, COG1649
NQU59_08080	COG1215	transferase activity, transferring glycosyl groups
NQU59_08120	COG2388	GCN5-related N-acetyl-transferase
NQU59_08130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQU59_08155	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NQU59_08160	COG1597	lipid kinase activity
NQU59_08200	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NQU59_08210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NQU59_08230	COG4771	TonB-dependent receptor
NQU59_08245	COG0288	reversible hydration of carbon dioxide
NQU59_08260	COG4181	ATPase activity
NQU59_08265	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NQU59_08275	COG0457	Tetratricopeptide repeat
NQU59_08275	COG0705	Rhomboid family
NQU59_08290	COG2070	2-Nitropropane dioxygenase
NQU59_08320	COG1215	transferase activity, transferring glycosyl groups
NQU59_08335	COG0415	Belongs to the DNA photolyase family
NQU59_08345	COG1252	NADH dehydrogenase
NQU59_08350	COG1686	Belongs to the peptidase S11 family
NQU59_08360	COG2351	hydroxyisourate hydrolase activity
NQU59_08390	COG1187	pseudouridine synthase activity
NQU59_08420	COG0612	Peptidase, M16
NQU59_08495	COG0352	thiamine-phosphate diphosphorylase activity
NQU59_08510	COG0564	pseudouridine synthase activity
NQU59_08520	COG0783	Belongs to the Dps family
NQU59_08550	COG1309	transcriptional regulator
NQU59_08555	COG2207	Transcriptional regulator
NQU59_08570	COG0318	PFAM AMP-dependent synthetase and ligase
NQU59_08580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NQU59_08585	COG0076	glutamate decarboxylase activity
NQU59_08595	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_08600	COG1522	sequence-specific DNA binding
NQU59_08605	COG3961	Belongs to the TPP enzyme family
NQU59_08610	COG1113	amino acid transport
NQU59_08620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NQU59_08635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQU59_08640	COG0616	signal peptide processing
NQU59_08665	COG0742	ribosomal rna small subunit methyltransferase
NQU59_08670	COG0768	penicillin binding
NQU59_08695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NQU59_08700	COG2878	Part of a membrane complex involved in electron transport
NQU59_08705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQU59_08715	COG3384	dioxygenase
NQU59_08730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NQU59_08810	COG0006	proline dipeptidase activity
NQU59_08815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQU59_08820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQU59_08875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NQU59_08880	COG1388	LysM domain
NQU59_08880	COG0741	lytic transglycosylase activity
NQU59_08885	COG4166	transmembrane transport
NQU59_08890	COG4174	ABC transporter (Permease)
NQU59_08895	COG4239	(ABC) transporter, permease
NQU59_08900	COG4172	Belongs to the ABC transporter superfamily
NQU59_08915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NQU59_08945	COG3739	integral membrane protein
NQU59_08965	COG0302	gtp cyclohydrolase
NQU59_08985	COG4771	TonB-dependent receptor
NQU59_08990	COG0308	aminopeptidase N
NQU59_09000	COG1823	symporter activity
NQU59_09005	COG0512	Glutamine amidotransferase of anthranilate synthase
NQU59_09010	COG0174	glutamine synthetase
NQU59_09015	COG3161	chorismate lyase activity
NQU59_09020	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NQU59_09070	COG0436	Aminotransferase
NQU59_09085	COG3706	GGDEF domain
NQU59_09090	COG0556	nucleotide-excision repair
NQU59_09170	COG5377	YqaJ viral recombinase family
NQU59_09430	COG0583	DNA-binding transcription factor activity
NQU59_09440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQU59_09445	COG1773	rubredoxin
NQU59_09455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQU59_09490	COG0222	ribosome binding
NQU59_09495	COG1253	flavin adenine dinucleotide binding
NQU59_09510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NQU59_09515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NQU59_09520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NQU59_09525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQU59_09545	COG0024	Methionine aminopeptidase
NQU59_09550	COG0052	Belongs to the universal ribosomal protein uS2 family
NQU59_09560	COG3015	lipoprotein NlpE involved in copper resistance
NQU59_09580	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NQU59_09585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NQU59_09585	COG0517	IMP dehydrogenase activity
NQU59_09590	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NQU59_09600	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NQU59_09605	COG1137	ATPase activity
NQU59_09615	COG1538	Outer membrane efflux protein
NQU59_09645	COG4122	O-methyltransferase activity
NQU59_09655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NQU59_09675	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_09680	COG0583	DNA-binding transcription factor activity
NQU59_09685	COG1914	H( )-stimulated, divalent metal cation uptake system
NQU59_09700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NQU59_09705	COG4770	biotin carboxylase activity
NQU59_09730	COG0671	phosphoesterase, PA-phosphatase related
NQU59_09765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQU59_09775	COG2207	Transcriptional regulator
NQU59_09780	COG2207	Transcriptional regulator
NQU59_09785	COG1073	alpha beta
NQU59_09790	COG1902	pentaerythritol trinitrate reductase activity
NQU59_09795	COG0583	DNA-binding transcription factor activity
NQU59_09830	COG4783	chaperone-mediated protein folding
NQU59_09845	COG1610	YqeY-like protein
NQU59_09880	COG0697	spore germination
NQU59_09915	COG2815	serine threonine protein kinase
NQU59_09915	COG0515	serine threonine protein kinase
NQU59_09945	COG1113	amino acid transport
NQU59_09995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NQU59_10000	COG1686	Belongs to the peptidase S11 family
NQU59_10030	COG0583	DNA-binding transcription factor activity
NQU59_10035	COG1067	ATP-dependent peptidase activity
NQU59_10075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NQU59_10080	COG1966	Carbon starvation protein
NQU59_10085	COG2879	small protein
NQU59_10090	COG0714	Associated with various cellular activities
NQU59_10130	COG3728	DNA packaging
NQU59_10130	COG5484	DNA packaging
NQU59_10175	COG1741	Belongs to the pirin family
NQU59_10190	COG0583	DNA-binding transcription factor activity
NQU59_10195	COG0697	spore germination
NQU59_10200	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQU59_10200	COG1902	pentaerythritol trinitrate reductase activity
NQU59_10210	COG0582	viral genome integration into host DNA
NQU59_10250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NQU59_10255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NQU59_10260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NQU59_10265	COG2205	protein histidine kinase activity
NQU59_10270	COG0745	RESPONSE REGULATOR receiver
NQU59_10310	COG2814	Major facilitator Superfamily
NQU59_10360	COG0625	glutathione transferase activity
NQU59_10365	COG0583	DNA-binding transcription factor activity
NQU59_10375	COG1346	cytolysis
NQU59_10400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQU59_10405	COG3713	MltA-interacting MipA family protein
NQU59_10420	COG2076	Multidrug Resistance protein
NQU59_10440	COG1570	exodeoxyribonuclease VII activity
NQU59_10445	COG1113	amino acid transport
NQU59_10480	COG2814	Major facilitator Superfamily
NQU59_10520	COG0596	Alpha beta hydrolase
NQU59_10535	COG0590	tRNA wobble adenosine to inosine editing
NQU59_10540	COG2807	transmembrane transport
NQU59_10570	COG0308	aminopeptidase N
NQU59_10580	COG1714	RDD family
NQU59_10600	COG0475	glutathione-regulated potassium exporter activity
NQU59_10600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NQU59_10605	COG3135	benzoate transporter
NQU59_10615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NQU59_10635	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NQU59_10670	COG0316	Belongs to the HesB IscA family
NQU59_10675	COG0822	iron-sulfur transferase activity
NQU59_10700	COG0776	regulation of translation
NQU59_10705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NQU59_10720	COG2137	regulation of response to DNA damage stimulus
NQU59_10725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NQU59_10730	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NQU59_10735	COG1011	Hydrolase
NQU59_10760	COG0268	Binds directly to 16S ribosomal RNA
NQU59_10765	COG0702	epimerase
NQU59_10770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NQU59_10785	COG0183	Belongs to the thiolase family
NQU59_10790	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_10800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NQU59_10820	COG0424	maF-like protein
NQU59_10845	COG0778	Nitroreductase
NQU59_10875	COG1286	toxin biosynthetic process
NQU59_10935	COG3634	alkyl hydroperoxide reductase activity
NQU59_10970	COG0436	Aminotransferase
NQU59_10980	COG0386	Belongs to the glutathione peroxidase family
NQU59_10990	COG1280	lysine exporter protein (LysE YggA)
NQU59_11005	COG1522	sequence-specific DNA binding
NQU59_11030	COG1942	4-Oxalocrotonate Tautomerase
NQU59_11045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQU59_11090	COG0012	GTP binding
NQU59_11095	COG2011	ABC-type metal ion transport system permease component
NQU59_11100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQU59_11105	COG1464	Belongs to the NlpA lipoprotein family
NQU59_11310	COG0753	catalase activity
NQU59_11340	COG3539	Fimbrial protein
NQU59_11365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NQU59_11365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NQU59_11385	COG1278	Cold shock
NQU59_11390	COG1278	Cold shock
NQU59_11435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQU59_11440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NQU59_11460	COG2353	YceI-like domain
NQU59_11465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQU59_11495	COG3153	acetyltransferase
NQU59_11510	COG3698	Phosphodiester glycosidase
NQU59_11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQU59_11540	COG0506	proline dehydrogenase activity
NQU59_11540	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NQU59_11540	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NQU59_11550	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQU59_11560	COG3397	chitin binding
NQU59_11575	COG2030	dehydratase
NQU59_11580	COG1132	(ABC) transporter
NQU59_11615	COG2026	Addiction module toxin, RelE StbE family
NQU59_11775	COG0668	transmembrane transport
NQU59_11780	COG3122	Protein conserved in bacteria
NQU59_11800	COG0640	Transcriptional regulator
NQU59_11825	COG2850	peptidyl-arginine hydroxylation
NQU59_11840	COG0824	Thioesterase
NQU59_11845	COG1454	alcohol dehydrogenase
NQU59_11880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQU59_11920	COG2831	hemolysin activation secretion protein
NQU59_11925	COG3210	domain, Protein
NQU59_12035	COG0625	glutathione transferase activity
NQU59_12045	COG1113	amino acid transport
NQU59_12050	COG2814	Major facilitator Superfamily
NQU59_12065	COG0439	Biotin carboxylase
NQU59_12080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQU59_12080	COG1116	anion transmembrane transporter activity
NQU59_12090	COG2223	nitrite transmembrane transporter activity
NQU59_12095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQU59_12095	COG2146	nitrite reductase [NAD(P)H] activity
NQU59_12100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQU59_12105	COG0243	molybdopterin cofactor binding
NQU59_12115	COG0477	Major facilitator Superfamily
NQU59_12120	COG0583	DNA-binding transcription factor activity
NQU59_12140	COG0243	molybdopterin cofactor binding
NQU59_12145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQU59_12160	COG0521	Mo-molybdopterin cofactor biosynthetic process
NQU59_12160	COG0315	cyclic pyranopterin monophosphate synthase activity
NQU59_12165	COG0303	'Molybdopterin
NQU59_12175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQU59_12180	COG0697	spore germination
NQU59_12185	COG2920	part of a sulfur-relay system
NQU59_12200	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NQU59_12255	COG2204	response regulator
NQU59_12260	COG3852	Histidine kinase
NQU59_12270	COG0528	UMP kinase activity
NQU59_12280	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQU59_12285	COG0575	Belongs to the CDS family
NQU59_12300	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NQU59_12310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQU59_12320	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQU59_12325	COG2207	Transcriptional regulator
NQU59_12330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQU59_12335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQU59_12340	COG1960	acyl-CoA dehydrogenase activity
NQU59_12345	COG1960	acyl-CoA dehydrogenase activity
NQU59_12355	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_12355	COG2030	dehydratase
NQU59_12360	COG3396	Phenylacetate-CoA oxygenase
NQU59_12365	COG3460	Phenylacetate-CoA oxygenase
NQU59_12370	COG3396	Phenylacetate-CoA oxygenase
NQU59_12375	COG2151	metal-sulfur cluster biosynthetic enzyme
NQU59_12380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NQU59_12385	COG1024	Enoyl-CoA hydratase
NQU59_12390	COG1024	Enoyl-CoA hydratase
NQU59_12395	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQU59_12400	COG0183	Belongs to the thiolase family
NQU59_12405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NQU59_12410	COG3327	negative regulation of DNA-templated transcription, initiation
NQU59_12425	COG1414	Transcriptional regulator
NQU59_12430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQU59_12480	COG2223	nitrite transmembrane transporter activity
NQU59_12495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQU59_12510	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NQU59_12535	COG4771	TonB-dependent receptor
NQU59_12550	COG0730	response to heat
NQU59_12580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQU59_12605	COG0477	Major facilitator Superfamily
NQU59_12625	COG0537	adenosine 5'-monophosphoramidase activity
NQU59_12640	COG2076	Multidrug Resistance protein
NQU59_12690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NQU59_12700	COG2226	methyltransferase
NQU59_12715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQU59_12725	COG0133	tryptophan synthase activity
NQU59_12740	COG3706	GGDEF domain
NQU59_12750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQU59_12755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQU59_12770	COG2249	NAD(P)H dehydrogenase (quinone) activity
NQU59_12780	COG4589	Belongs to the CDS family
NQU59_12795	COG0671	phosphoesterase, PA-phosphatase related
NQU59_12795	COG2453	phosphatase
NQU59_12800	COG2267	carboxylic ester hydrolase activity
NQU59_12805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NQU59_12840	COG0583	DNA-binding transcription factor activity
NQU59_12870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQU59_12890	COG3052	prosthetic group binding
NQU59_12895	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NQU59_12945	COG4774	siderophore transport
NQU59_12975	COG1271	oxidase subunit
NQU59_12980	COG1294	oxidase, subunit
NQU59_12990	COG2814	Major facilitator Superfamily
NQU59_13040	COG1595	DNA-templated transcription, initiation
NQU59_13105	COG0789	Transcriptional regulator
NQU59_13115	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQU59_13115	COG1902	pentaerythritol trinitrate reductase activity
NQU59_13130	COG3268	Saccharopine dehydrogenase
NQU59_13150	COG1595	DNA-templated transcription, initiation
NQU59_13160	COG3220	belongs to the UPF0276 family
NQU59_13175	COG0745	RESPONSE REGULATOR receiver
NQU59_13180	COG2205	protein histidine kinase activity
NQU59_13215	COG1944	ATP diphosphatase activity
NQU59_13220	COG0583	DNA-binding transcription factor activity
NQU59_13230	COG1802	Transcriptional regulator
NQU59_13250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NQU59_13260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQU59_13315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQU59_13365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NQU59_13370	COG0148	phosphopyruvate hydratase activity
NQU59_13405	COG1902	pentaerythritol trinitrate reductase activity
NQU59_13405	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQU59_13415	COG2267	carboxylic ester hydrolase activity
NQU59_13430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQU59_13435	COG0488	(ABC) transporter
NQU59_13455	COG0542	response to heat
NQU59_13460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NQU59_13465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NQU59_13485	COG1785	Belongs to the alkaline phosphatase family
NQU59_13505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQU59_13510	COG0569	domain protein
NQU59_13515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQU59_13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQU59_13560	COG1294	oxidase, subunit
NQU59_13565	COG4890	Cyd operon protein YbgT
NQU59_13600	COG0552	protein localization to endoplasmic reticulum
NQU59_13625	COG0517	IMP dehydrogenase activity
NQU59_13625	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NQU59_13630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQU59_13635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NQU59_13645	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQU59_13650	COG0583	DNA-binding transcription factor activity
NQU59_13655	COG0024	Methionine aminopeptidase
NQU59_13695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NQU59_13700	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NQU59_13715	COG2814	Major facilitator Superfamily
NQU59_13720	COG1309	transcriptional regulator
NQU59_13725	COG2431	L-lysine efflux transmembrane transporter activity
NQU59_13755	COG0776	regulation of translation
NQU59_13820	COG0084	hydrolase, TatD family'
NQU59_13835	COG3328	transposase activity
NQU59_13860	COG1663	tetraacyldisaccharide 4'-kinase activity
NQU59_13865	COG1132	(ABC) transporter
NQU59_13875	COG0811	peptide transport
NQU59_13880	COG1475	DNA binding
NQU59_13885	COG1192	Involved in chromosome partitioning
NQU59_13895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NQU59_13910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NQU59_13920	COG0513	Belongs to the DEAD box helicase family
NQU59_13940	COG2363	Small membrane protein
NQU59_13990	COG4650	regulator
NQU59_14000	COG1234	tRNA 3'-trailer cleavage
NQU59_14010	COG1690	Belongs to the RtcB family
NQU59_14025	COG0430	RNA-3'-phosphate cyclase activity
NQU59_14040	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NQU59_14045	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQU59_14055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NQU59_14070	COG1960	acyl-CoA dehydrogenase activity
NQU59_14085	COG3139	Protein of unknown function (DUF1315)
NQU59_14090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQU59_14095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQU59_14105	COG0494	nUDIX hydrolase
NQU59_14115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NQU59_14120	COG1720	tRNA m6t6A37 methyltransferase activity
NQU59_14150	COG0583	DNA-binding transcription factor activity
NQU59_14155	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NQU59_14170	COG2814	Major facilitator Superfamily
NQU59_14175	COG4607	ABC-type enterochelin transport system periplasmic component
NQU59_14180	COG4604	ABC transporter, ATP-binding protein
NQU59_14185	COG4605	iron ion homeostasis
NQU59_14190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQU59_14195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQU59_14200	COG0471	metal ion transport
NQU59_14245	COG0729	surface antigen
NQU59_14250	COG0477	Major facilitator Superfamily
NQU59_14275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NQU59_14285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NQU59_14295	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NQU59_14300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQU59_14335	COG4682	membrane
NQU59_14365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NQU59_14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQU59_14395	COG1116	anion transmembrane transporter activity
NQU59_14410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQU59_14415	COG0864	Transcriptional regulator
NQU59_14420	COG0439	Biotin carboxylase
NQU59_14465	COG1131	(ABC) transporter
NQU59_14470	COG0842	Transport permease protein
NQU59_14485	COG0772	Belongs to the SEDS family
NQU59_14490	COG2951	lytic endotransglycosylase activity
NQU59_14510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQU59_14515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NQU59_14525	COG1643	Atp-dependent helicase
NQU59_14545	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQU59_14585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQU59_14690	COG1765	OsmC-like protein
NQU59_14700	COG0501	Belongs to the peptidase M48B family
NQU59_14705	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NQU59_14710	COG2072	flavoprotein involved in K transport
NQU59_14730	COG1309	transcriptional regulator
NQU59_14735	COG5002	protein histidine kinase activity
NQU59_14740	COG0745	RESPONSE REGULATOR receiver
NQU59_14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQU59_14750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQU59_14755	COG1538	Outer membrane efflux protein
NQU59_14775	COG1876	peptidase activity
NQU59_14790	COG2837	iron assimilation
NQU59_14795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NQU59_14800	COG0243	molybdopterin cofactor binding
NQU59_14815	COG1271	oxidase subunit
NQU59_14820	COG1294	oxidase, subunit
NQU59_14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQU59_14870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQU59_14875	COG0010	Belongs to the arginase family
NQU59_14885	COG1113	amino acid transport
NQU59_14905	COG2188	Transcriptional regulator
NQU59_14915	COG0583	DNA-binding transcription factor activity
NQU59_14925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQU59_14935	COG2885	chlorophyll binding
NQU59_14955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_14965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQU59_14990	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NQU59_14995	COG4266	Belongs to the allantoicase family
NQU59_15000	COG2186	Transcriptional regulator
NQU59_15005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NQU59_15020	COG2233	PERMEase
NQU59_15025	COG2351	hydroxyisourate hydrolase activity
NQU59_15040	COG4993	Dehydrogenase
NQU59_15045	COG3659	wide pore channel activity
NQU59_15050	COG3420	alginic acid biosynthetic process
NQU59_15055	COG0710	3-dehydroquinate dehydratase activity
NQU59_15060	COG3485	protocatechuate 3,4-dioxygenase
NQU59_15065	COG3485	protocatechuate 3,4-dioxygenase
NQU59_15070	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQU59_15075	COG2271	Major facilitator Superfamily
NQU59_15080	COG0596	Alpha beta hydrolase
NQU59_15085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQU59_15090	COG0183	Belongs to the thiolase family
NQU59_15095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NQU59_15100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NQU59_15105	COG1414	Transcriptional regulator
NQU59_15110	COG2985	domain, Protein
NQU59_15125	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_15130	COG4638	Rieske (2fe-2S)
NQU59_15135	COG0657	acetylesterase activity
NQU59_15145	COG0473	3-isopropylmalate dehydrogenase activity
NQU59_15150	COG0583	DNA-binding transcription factor activity
NQU59_15205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQU59_15225	COG0531	amino acid
NQU59_15230	COG4303	Ethanolamine ammonia lyase large subunit
NQU59_15240	COG0519	Catalyzes the synthesis of GMP from XMP
NQU59_15240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NQU59_15245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQU59_15255	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQU59_15270	COG0778	Nitroreductase
NQU59_15275	COG2249	NAD(P)H dehydrogenase (quinone) activity
NQU59_15285	COG0697	spore germination
NQU59_15290	COG1923	regulation of RNA biosynthetic process
NQU59_15300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NQU59_15305	COG0802	atpase or kinase
NQU59_15325	COG1187	pseudouridine synthase activity
NQU59_15335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQU59_15340	COG5001	Diguanylate cyclase
NQU59_15340	COG3300	MHYT domain
NQU59_15365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NQU59_15370	COG1845	cytochrome c oxidase, subunit III
NQU59_15375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NQU59_15405	COG0305	Participates in initiation and elongation during chromosome replication
NQU59_15410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NQU59_15425	COG1305	Transglutaminase-like
NQU59_15435	COG2308	Evidence 4 Homologs of previously reported genes of
NQU59_15450	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NQU59_15460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQU59_15470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NQU59_15490	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQU59_15500	COG3038	cytochrome b561
NQU59_15520	COG2827	Endonuclease containing a URI domain
NQU59_15570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NQU59_15575	COG2252	PERMEase
NQU59_15640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NQU59_15645	COG0138	bifunctional purine biosynthesis protein purh
NQU59_15655	COG1464	Belongs to the NlpA lipoprotein family
NQU59_15660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQU59_15665	COG2011	ABC-type metal ion transport system permease component
NQU59_15670	COG1280	lysine exporter protein (LysE YggA)
NQU59_15685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQU59_15695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NQU59_15700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NQU59_15705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NQU59_15715	COG0281	malic enzyme
NQU59_15715	COG0280	phosphate acetyltransferase
NQU59_15740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NQU59_15755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQU59_15760	COG0571	ribonuclease III activity
NQU59_15775	COG0481	GTPase activity
NQU59_15785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQU59_15800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NQU59_15805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQU59_15810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NQU59_15820	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NQU59_15825	COG4208	sulfate ABC transporter
NQU59_15830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NQU59_15835	COG0583	DNA-binding transcription factor activity
NQU59_15850	COG0602	queuosine metabolic process
NQU59_15855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NQU59_15870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NQU59_15885	COG1056	cytidyltransferase-related domain
NQU59_15885	COG1051	belongs to the nudix hydrolase family
NQU59_15890	COG1024	Enoyl-CoA hydratase
NQU59_15895	COG1929	Belongs to the glycerate kinase type-1 family
NQU59_15940	COG2814	Major facilitator Superfamily
NQU59_15945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQU59_15945	COG0047	phosphoribosylformylglycinamidine synthase activity
NQU59_15980	COG0824	Thioesterase
NQU59_16000	COG0823	Involved in the tonB-independent uptake of proteins
NQU59_16020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQU59_16050	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQU59_16055	COG0628	permease
NQU59_16065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NQU59_16075	COG3772	lysozyme
NQU59_16165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NQU59_16165	COG0616	signal peptide processing
NQU59_16175	COG0658	competence protein
NQU59_16175	COG2333	competence protein COMEC
NQU59_16180	COG1136	(ABC) transporter
NQU59_16185	COG4591	ABC-type transport system involved in lipoprotein release permease component
NQU59_16195	COG0697	spore germination
NQU59_16200	COG1671	Belongs to the UPF0178 family
NQU59_16235	COG0842	Transport permease protein
NQU59_16245	COG0463	Glycosyl transferase, family 2
NQU59_16255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQU59_16275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NQU59_16290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NQU59_16295	COG0019	diaminopimelate decarboxylase activity
NQU59_16305	COG1113	amino acid transport
NQU59_16320	COG0306	phosphate transporter
NQU59_16330	COG2852	Protein conserved in bacteria
NQU59_16340	COG2066	Belongs to the glutaminase family
NQU59_16345	COG0242	peptide deformylase activity
NQU59_16365	COG0589	response to stress
NQU59_16405	COG2175	clavaminate synthase activity
NQU59_16410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_16415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NQU59_16420	COG4521	taurine ABC transporter
NQU59_16430	COG1045	serine acetyltransferase
NQU59_16435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQU59_16440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQU59_16445	COG1280	lysine exporter protein (LysE YggA)
NQU59_16455	COG2188	Transcriptional regulator
NQU59_16460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NQU59_16475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_16480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NQU59_16495	COG1230	cation diffusion facilitator family transporter
NQU59_16510	COG4149	molybdate abc transporter
NQU59_16515	COG0725	ABC transporter, periplasmic molybdate-binding protein
NQU59_16620	COG0671	phosphoesterase, PA-phosphatase related
NQU59_16640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NQU59_16640	COG3008	intermembrane lipid transfer
NQU59_16645	COG2995	paraquat-inducible protein a
NQU59_16655	COG0833	amino acid
NQU59_16670	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_16680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQU59_16685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQU59_16695	COG0281	malic enzyme
NQU59_16700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NQU59_16705	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_16730	COG3618	amidohydrolase
NQU59_16735	COG4774	siderophore transport
NQU59_16755	COG1960	acyl-CoA dehydrogenase activity
NQU59_16765	COG0583	DNA-binding transcription factor activity
NQU59_16770	COG4948	Mandelate Racemase Muconate Lactonizing
NQU59_16775	COG4829	muconolactone delta-isomerase
NQU59_16785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NQU59_16790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NQU59_16795	COG0183	Belongs to the thiolase family
NQU59_16800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQU59_16805	COG1012	belongs to the aldehyde dehydrogenase family
NQU59_16820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQU59_16830	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_16840	COG4638	Rieske (2fe-2S)
NQU59_16855	COG0154	amidase activity
NQU59_16865	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQU59_16870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NQU59_16880	COG2814	Major facilitator Superfamily
NQU59_16890	COG0583	DNA-binding transcription factor activity
NQU59_16895	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NQU59_16915	COG0789	Transcriptional regulator
NQU59_16925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQU59_16930	COG0235	Class ii aldolase
NQU59_16935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQU59_16985	COG0745	RESPONSE REGULATOR receiver
NQU59_16990	COG0642	Histidine kinase
NQU59_17005	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQU59_17035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQU59_17070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NQU59_17080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_17085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQU59_17100	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NQU59_17125	COG1132	(ABC) transporter
NQU59_17130	COG1132	(ABC) transporter
NQU59_17180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQU59_17185	COG0601	transmembrane transport
NQU59_17250	COG2072	flavoprotein involved in K transport
NQU59_17300	COG0405	Gamma-glutamyltransferase
NQU59_17305	COG2814	Major facilitator Superfamily
NQU59_17310	COG1566	PFAM secretion protein HlyD family protein
NQU59_17320	COG2226	methyltransferase
NQU59_17325	COG2050	protein possibly involved in aromatic compounds catabolism
NQU59_17335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NQU59_17340	COG1090	epimerase
NQU59_17370	COG0420	3'-5' exonuclease activity
NQU59_17380	COG1968	undecaprenyl-diphosphatase activity
NQU59_17405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NQU59_17425	COG0121	glutamine amidotransferase
NQU59_17445	COG0756	dUTP diphosphatase activity
NQU59_17450	COG0210	DNA helicase
NQU59_17455	COG2885	chlorophyll binding
NQU59_17460	COG0204	Acyl-transferase
NQU59_17470	COG0850	regulation of cytokinetic process
NQU59_17475	COG2894	cell division
NQU59_17480	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NQU59_17490	COG1674	ftsk spoiiie
NQU59_17495	COG0492	ferredoxin-NADP+ reductase activity
NQU59_17500	COG0500	methyltransferase
NQU59_17505	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NQU59_17515	COG0456	acetyltransferase
NQU59_17535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQU59_17560	COG1981	membrane
NQU59_17585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQU59_17585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NQU59_17610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQU59_17635	COG1496	oxidoreductase activity
NQU59_17640	COG0564	pseudouridine synthase activity
NQU59_17650	COG0358	DNA primase activity
NQU59_17665	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NQU59_17695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NQU59_17730	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQU59_17740	COG0351	phosphomethylpyrimidine kinase
NQU59_17740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NQU59_17740	COG0352	thiamine-phosphate diphosphorylase activity
NQU59_17745	COG1652	LysM domain
NQU59_17755	COG1028	Short-chain dehydrogenase reductase Sdr
NQU59_17765	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQU59_17770	COG1399	metal-binding, possibly nucleic acid-binding protein
NQU59_17775	COG3101	peptidyl-lysine hydroxylation
NQU59_17780	COG0009	L-threonylcarbamoyladenylate synthase
NQU59_17790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NQU59_17795	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQU59_17820	COG0339	signal peptide processing
NQU59_17830	COG4166	transmembrane transport
NQU59_17880	COG4106	trans-aconitate 2-methyltransferase activity
NQU59_17895	COG0596	Alpha beta hydrolase
NQU59_17895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NQU59_17895	COG2226	methyltransferase
NQU59_17910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NQU59_17935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQU59_17950	COG1196	nuclear chromosome segregation
NQU59_17970	COG0730	response to heat
NQU59_17990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NQU59_18025	COG0644	oxidoreductase
NQU59_18080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQU59_18085	COG0489	protein tyrosine kinase activity
NQU59_18120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQU59_18120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQU59_18130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQU59_18140	COG4716	Myosin-crossreactive antigen
NQU59_18145	COG2226	methyltransferase
NQU59_18170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NQU59_18175	COG2081	HI0933 family
NQU59_18185	COG0668	transmembrane transport
NQU59_18205	COG0583	DNA-binding transcription factor activity
NQU59_18215	COG1278	Cold shock
NQU59_18235	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQU59_18240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NQU59_18245	COG0713	ATP synthesis coupled electron transport
NQU59_18255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQU59_18270	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NQU59_18280	COG0649	NAD binding
NQU59_18280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQU59_18290	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NQU59_18305	COG2205	protein histidine kinase activity
NQU59_18310	COG0745	RESPONSE REGULATOR receiver
NQU59_18325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQU59_18340	COG2207	Transcriptional regulator
NQU59_18380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NQU59_18385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NQU59_18390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NQU59_18415	COG2132	Multicopper oxidase
NQU59_18425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NQU59_18455	COG1968	undecaprenyl-diphosphatase activity
NQU59_18460	COG1214	PFAM Peptidase M22, glycoprotease
NQU59_18470	COG0494	nUDIX hydrolase
NQU59_18520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NQU59_18530	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NQU59_18535	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQU59_18590	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
NQU59_18615	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD