locus-tag	class	description
AS4_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AS4_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AS4_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS4_00050	ENOG4108821	RND type efflux pump
AS4_00060	ENOG4105C5H	ABC transporter
AS4_00070	ENOG4108821	RND type efflux pump
AS4_00080	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AS4_00090	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AS4_00120	ENOG4108821	RND type efflux pump
AS4_00170	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AS4_00220	ENOG4108XC3	NADH ubiquinone oxidoreductase
AS4_00230	ENOG4105C8J	)-transporter
AS4_00250	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AS4_00260	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AS4_00300	ENOG4105C01	Dihydroxy-acid dehydratase
AS4_00340	ENOG4105CFQ	glutamine synthetase
AS4_00380	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AS4_00390	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AS4_00400	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AS4_00410	ENOG4105DTN	riboflavin biosynthesis protein ribF
AS4_00440	ENOG4105C2W	permease
AS4_00450	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AS4_00460	ENOG4105J7D	transcriptional regulator
AS4_00550	ENOG4105F27	Major Facilitator
AS4_00560	ENOG4105CV8	reductase
AS4_00570	ENOG4105HEI	LysR family (Transcriptional regulator
AS4_00600	ENOG4105DQ4	alcohol dehydrogenase
AS4_00610	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AS4_00640	ENOG4105CEN	a g-specific adenine glycosylase
AS4_00680	ENOG4108ZZ3	UPF0260 protein
AS4_00700	ENOG4105D1H	recombination factor protein RarA
AS4_00740	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS4_00790	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS4_00800	ENOG4108RWI	nicotinamidase
AS4_00810	ENOG4105C09	Bile acid
AS4_00820	ENOG4105EWC	Purine nucleoside phosphorylase
AS4_00850	ENOG4108IND	Tetr family transcriptional regulator
AS4_00890	ENOG4105PGM	cation diffusion facilitator family transporter
AS4_00900	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AS4_00920	ENOG4108ZAI	phosphatidylglycerophosphatase a
AS4_00930	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AS4_00940	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AS4_00950	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AS4_00960	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AS4_00980	ENOG4105EAC	phosphoserine phosphatase
AS4_01030	ENOG4105KHC	sulfurtransferase
AS4_01070	ENOG4105BZU	Histidine kinase
AS4_01080	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AS4_01120	ENOG4107QJQ	Mate efflux family protein
AS4_01130	ENOG4105CHM	Aminotransferase
AS4_01230	ENOG4105ES4	Nitrilase
AS4_01270	ENOG4106BRA	Membrane
AS4_01310	ENOG4105D9M	gamma-glutamylcysteine synthetase
AS4_01320	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AS4_01350	ENOG4105IPS	esterase
AS4_01360	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS4_01370	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
AS4_01380	ENOG4105C32	Amino acid ABC transporter (Permease)
AS4_01400	ENOG4105C0Z	ABC transporter
AS4_01410	ENOG4108IV0	ABC, transporter
AS4_01500	ENOG4105BZU	Histidine kinase
AS4_01510	ENOG4105BZU	Histidine kinase
AS4_01540	ENOG4105KUZ	arsenate reductase
AS4_01550	ENOG4105CGK	Exodeoxyribonuclease III
AS4_01580	ENOG4107RBI	VanW family
AS4_01590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AS4_01610	ENOG4105D7Z	glutathione synthase
AS4_01630	ENOG4105DFU	Cell wall formation (By similarity)
AS4_01650	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AS4_01660	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AS4_01670	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AS4_01680	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS4_01710	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AS4_01720	ENOG4107QSN	dihydrolipoamide acetyltransferase
AS4_01770	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AS4_01800	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AS4_01860	ENOG4105EUB	pirin domain protein
AS4_01900	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AS4_01910	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS4_01950	ENOG4105DWF	phosphomethylpyrimidine kinase
AS4_01970	ENOG4107RDB	Major Facilitator
AS4_01980	ENOG4108UUM	single-stranded DNA-binding protein
AS4_02020	ENOG4105D3R	alkyl hydroperoxide reductase
AS4_02030	ENOG4105CC0	LysR family Transcriptional regulator
AS4_02040	ENOG4105CHJ	isochorismatase hydrolase
AS4_02050	ENOG4105EUB	pirin domain protein
AS4_02060	ENOG4105CVN	desaturase
AS4_02190	ENOG4105DFH	Transport of potassium into the cell (By similarity)
AS4_02230	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AS4_02270	ENOG4105CH7	arginosuccinase
AS4_02280	ENOG4108HRK	Histidine kinase
AS4_02290	ENOG4108NEV	two component transcriptional regulator, LytTR family
AS4_02300	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AS4_02350	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
AS4_02380	ENOG4105GVR	general secretion pathway protein D
AS4_02400	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS4_02430	ENOG4105PM1	preprotein translocase subunit SecE
AS4_02440	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AS4_02460	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AS4_02480	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AS4_02490	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS4_02500	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS4_02550	ENOG4105D3Y	Na H antiporter
AS4_02580	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AS4_02610	ENOG4107ZXU	DSBA oxidoreductase
AS4_02670	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_02680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS4_02710	ENOG4108QCI	YvbH-like oligomerisation region
AS4_02760	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AS4_02820	ENOG4108M8S	permease YjgP YjgQ family protein
AS4_02830	ENOG4108K5H	permease YjgP YjgQ family protein
AS4_02840	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AS4_02850	ENOG4105CN1	protease
AS4_02860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS4_02870	ENOG4107TUY	Histidine kinase
AS4_02890	ENOG41061WM	D-Alanyl-D-Alanine
AS4_02930	ENOG4105D6E	homoserine dehydrogenase
AS4_02940	ENOG4105T95	Thiol disulfide interChange protein
AS4_02950	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AS4_02970	ENOG4105CE1	Ferrous iron transport protein b
AS4_02990	ENOG4105BZ1	(ABC) transporter
AS4_03010	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
AS4_03030	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
AS4_03050	ENOG4105Y49	secretion protein, HlyD family
AS4_03070	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AS4_03090	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AS4_03100	ENOG4105NBK	UPF0345 protein
AS4_03110	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AS4_03130	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AS4_03160	ENOG4107QHF	type ii secretion system protein e
AS4_03180	ENOG4107EJC	Preprotein translocase subunit SecG
AS4_03190	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AS4_03200	ENOG4105CHV	Transcription elongation factor NusA
AS4_03210	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AS4_03220	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AS4_03240	ENOG4108V0P	LemA family
AS4_03250	ENOG4105HA9	of methanol dehydrogenase type
AS4_03300	ENOG4108YSG	O-Antigen polymerase
AS4_03310	ENOG4108UQY	Iron-storage protein
AS4_03330	ENOG4105KME	endoribonuclease L-psp
AS4_03340	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS4_03350	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AS4_03360	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AS4_03380	ENOG4106855	Competence protein
AS4_03440	ENOG4105KHS	type IV fimbrial pilin protein
AS4_03450	ENOG4105K5M	30s ribosomal protein S16
AS4_03460	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AS4_03480	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AS4_03490	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS4_03500	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS4_03510	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
AS4_03520	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AS4_03570	ENOG4108R1E	Serine threonine protein phosphatase 1
AS4_03590	ENOG4107AQZ	Membrane
AS4_03600	ENOG4108JQ1	Dehydrogenase
AS4_03610	ENOG4105CQB	FAD linked oxidase domain protein
AS4_03640	ENOG4105CPF	Cell wall formation (By similarity)
AS4_03660	ENOG4105EUB	pirin domain protein
AS4_03680	ENOG4107QF7	multi-drug
AS4_03690	ENOG4105VCH	membrane
AS4_03710	ENOG4105EM2	membrane
AS4_03730	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS4_03740	ENOG4105IPI	Membrane
AS4_03860	ENOG4105C5I	Dehydrogenase
AS4_03940	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AS4_04000	ENOG4105IQ5	FAD linked oxidase domain protein
AS4_04030	ENOG4105W87	Cbs domain
AS4_04040	ENOG41067S9	phage shock protein C, PspC
AS4_04080	ENOG4105J5T	Amp-dependent synthetase and ligase
AS4_04090	ENOG4105C03	ribonuclease
AS4_04100	ENOG4105EI2	Pseudouridine synthase
AS4_04110	ENOG4107XGZ	Hydrolase
AS4_04120	ENOG4105D29	Helix-turn-helix type 11 domain protein
AS4_04150	ENOG4108W5M	transcriptional regulator
AS4_04230	ENOG4105CH6	catalase
AS4_04310	ENOG4105CSU	acyl-Coa dehydrogenase
AS4_04350	ENOG4105CDV	Ompa motb domain protein
AS4_04380	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AS4_04390	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS4_04450	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AS4_04480	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS4_04500	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AS4_04540	ENOG4105HDK	L-asparaginase
AS4_04610	ENOG4105D1S	lipid A biosynthesis
AS4_04620	ENOG4108UVJ	appr-1-p processing domain protein
AS4_04650	ENOG4105C5H	ABC transporter
AS4_04660	ENOG41069P5	Protein slyX homolog
AS4_04670	ENOG4108WAV	Transcriptional regulator
AS4_04680	ENOG4105C5A	transporter
AS4_04710	ENOG4107R7A	Allophanate hydrolase subunit 2
AS4_04720	ENOG4108JIK	carboxylase
AS4_04740	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AS4_04750	ENOG4105KVH	Transcriptional regulator
AS4_04770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AS4_04820	ENOG4105BZW	Glycerate kinase
AS4_04840	ENOG4105C4R	Atp-dependent dna helicase
AS4_04880	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AS4_04890	ENOG4105W0E	50S ribosomal protein L33
AS4_04900	ENOG4105KDC	50s ribosomal protein l28
AS4_04910	ENOG4107RGH	Aldehyde dehydrogenase
AS4_04920	ENOG41062JF	Transcriptional regulator
AS4_04930	ENOG4105CIY	formyltetrahydrofolate deformylase
AS4_04980	ENOG4107QPB	Beta-lactamase domain protein
AS4_05010	ENOG4105NAU	thioesterase Superfamily protein
AS4_05040	ENOG4108VPT	UPF0234 protein
AS4_05050	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AS4_05080	ENOG4105K9H	YciI-like protein
AS4_05100	ENOG4105DB7	PHP domain protein
AS4_05120	ENOG4105C9A	Phoh family
AS4_05130	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AS4_05140	ENOG4105E4C	Lytic transglycosylase catalytic
AS4_05160	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AS4_05200	ENOG4105D6S	protein involved in catabolism of external DNA
AS4_05210	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AS4_05280	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AS4_05290	ENOG4108XI2	Domain of unknown function (DUF1963)
AS4_05370	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AS4_05400	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AS4_05440	ENOG4105DWV	Homoserine O-trans-acetylase
AS4_05460	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AS4_05490	ENOG4108ESX	Receptor
AS4_05520	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AS4_05570	ENOG4107GFK	fumarate
AS4_05590	ENOG4105E0K	tonB-dependent siderophore receptor
AS4_05600	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AS4_05610	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AS4_05660	ENOG4105CN1	protease
AS4_05670	ENOG4105BZU	Histidine kinase
AS4_05680	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AS4_05710	ENOG4105F8V	Hydrolase, tatD family
AS4_05720	ENOG4107QM5	aconitate hydratase
AS4_05730	ENOG4105CUZ	uba thif-type nad fad binding protein
AS4_05770	ENOG4107RSM	transcriptional regulator
AS4_05780	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS4_05820	ENOG4105EQ1	Transcriptional regulator
AS4_05860	ENOG4105ETE	Transcriptional regulator (LacI family
AS4_05890	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AS4_05930	ENOG4105CUY	Mechanosensitive ion channel
AS4_06010	ENOG4107WMG	L,D-carboxypeptidase
AS4_06040	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS4_06050	ENOG4105W8H	transhydrogenase (subunit alpha
AS4_06060	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AS4_06080	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS4_06090	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AS4_06100	ENOG4105VIE	preprotein translocase, subunit YajC
AS4_06190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AS4_06610	ENOG4105ED4	portal protein
AS4_06640	ENOG4105EB3	Histidine kinase
AS4_06650	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AS4_06660	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AS4_06700	ENOG4105C39	capsular polysaccharide phosphotransferase
AS4_06730	ENOG4107J0A	lipopolysaccharide biosynthetic process
AS4_06740	ENOG4105W1T	Glycosyl Transferase
AS4_06750	ENOG4105W1T	Glycosyl Transferase
AS4_06760	ENOG4105EXC	Acyl-transferase
AS4_06790	ENOG4107J0A	lipopolysaccharide biosynthetic process
AS4_06820	ENOG4105C9M	aspartyl-trna synthetase
AS4_06850	ENOG4105UGU	tonB-dependent Receptor
AS4_06950	ENOG4105CSU	acyl-Coa dehydrogenase
AS4_06960	ENOG4105CSU	acyl-Coa dehydrogenase
AS4_06980	ENOG4105CEY	Amp-dependent synthetase and ligase
AS4_06990	ENOG4108ZX5	transcriptional regulator
AS4_07000	ENOG4107R72	Ceramidase
AS4_07010	ENOG4105QE3	oxidoreductase
AS4_07040	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AS4_07060	ENOG4105CYM	Glutathione S-transferase
AS4_07090	ENOG4105W39	Membrane
AS4_07120	ENOG41082NX	50s ribosomal protein l35
AS4_07130	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AS4_07200	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AS4_07210	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS4_07230	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AS4_07250	ENOG4105C9X	ppx gppa phosphatase
AS4_07270	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AS4_07280	ENOG4105II7	pyrroline-5-carboxylate reductase
AS4_07290	ENOG4108VIA	integral membrane protein
AS4_07300	ENOG4105C2M	dna polymerase I
AS4_07320	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_07340	ENOG4108WHA	ompa motb domain protein
AS4_07350	ENOG4105CDV	Ompa motb domain protein
AS4_07370	ENOG4105E0Y	RtcB Protein
AS4_07390	ENOG4108IQI	permease
AS4_07410	ENOG4105C2W	permease
AS4_07430	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AS4_07450	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AS4_07470	ENOG4105TW1	Carbohydrate-selective porin OprB
AS4_07480	ENOG4105CHB	tonB-dependent Receptor
AS4_07490	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS4_07520	ENOG4105T95	Thiol disulfide interChange protein
AS4_07580	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AS4_07590	ENOG4108I0Z	Aconitate hydratase
AS4_07660	ENOG4105BZU	Histidine kinase
AS4_07700	ENOG4105KB2	stringent starvation protein b
AS4_07710	ENOG4107MKT	Stringent starvation protein a
AS4_07730	ENOG4108UJD	30S ribosomal protein S9
AS4_07740	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AS4_07770	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AS4_07780	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AS4_07790	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AS4_07840	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AS4_07860	ENOG4107RZC	phospholipase d
AS4_07930	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AS4_07950	ENOG4105CSH	Transporter
AS4_07960	ENOG4105C26	Dehydrogenase
AS4_08000	ENOG4108DNJ	Pfam:TonB
AS4_08020	ENOG4107QSI	ABC, transporter
AS4_08030	ENOG4108J59	Extracellular solute-binding protein, family 5
AS4_08060	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS4_08090	ENOG4105FE9	pseudouridine synthase
AS4_08100	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AS4_08110	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
AS4_08130	ENOG4105CS6	Rhs element vgr protein
AS4_08190	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
AS4_08250	ENOG4105DDI	hemolysin-type calcium-binding region
AS4_08270	ENOG4105D5G	Transposase
AS4_08420	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS4_08440	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AS4_08450	ENOG4107EXC	regulatoR
AS4_08460	ENOG4105JJR	Histidine kinase
AS4_08510	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AS4_08540	ENOG4105GKE	subunit e
AS4_08550	ENOG4107QIZ	NADH dehydrogenase
AS4_08560	ENOG4108IEH	NADH dehydrogenase subunit g
AS4_08570	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AS4_08580	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS4_08590	ENOG4107UFS	subunit j
AS4_08600	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AS4_08610	ENOG4105D65	subunit l
AS4_08620	ENOG4105C8S	subunit m
AS4_08640	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AS4_08670	ENOG4105DUM	transcriptional regulator, lysR family
AS4_08680	ENOG4105DP0	ferredoxin-NADP reductase
AS4_08690	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AS4_08700	ENOG4105D52	delta-aminolevulinic acid dehydratase
AS4_08710	ENOG4108VUY	thioesterase Superfamily protein
AS4_08720	ENOG4105CW7	secretion protein, HlyD family
AS4_08730	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AS4_08750	ENOG4107R3N	Filamentation induced by cAMP protein fic
AS4_08760	ENOG4105C3R	Methionine synthase
AS4_08780	ENOG4105CJ3	phosphate transporter
AS4_08790	ENOG4108MRJ	
AS4_08810	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AS4_08820	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AS4_08880	ENOG4105D4T	Citrate transporter
AS4_08890	ENOG4105C37	(CBS) domain
AS4_08910	ENOG4107RET	Isocitrate lyase
AS4_08940	ENOG4107QMS	site-determining protein
AS4_08950	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AS4_08970	ENOG4106HNH	Acyl-transferase
AS4_08980	ENOG4108ZG0	Ompa motb domain protein
AS4_08990	ENOG4105C4R	Atp-dependent dna helicase
AS4_09000	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AS4_09010	ENOG4107QKV	phosphomannomutase
AS4_09020	ENOG4105CAS	nag kinase
AS4_09040	ENOG4105E7A	Glutamine amidotransferase
AS4_09070	ENOG4105VDB	UPF0125 protein
AS4_09090	ENOG41090R7	Ferric uptake
AS4_09100	ENOG4105CZX	twitching motility protein
AS4_09110	ENOG4105CZX	twitching motility protein
AS4_09120	ENOG4105DFA	alanine racemase domain protein
AS4_09130	ENOG4108QM7	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AS4_09180	ENOG4105EYH	Exonuclease
AS4_09190	ENOG4107RH8	nuclease SbcCD subunit D
AS4_09230	ENOG4108RF1	Protein of unknown function DUF2625
AS4_09260	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AS4_09300	ENOG4105D6U	Sodium Glutamate Symporter
AS4_09310	ENOG4105CAH	Chromate
AS4_09320	ENOG4105D78	K07001 NTE family protein
AS4_09380	ENOG4105CKI	cobalamin synthesis protein
AS4_09390	ENOG4108VWS	Yaeq family
AS4_09430	ENOG4107BJW	polysaccharide deacetylase
AS4_09440	ENOG4105CND	Glycosyl transferase, family 2
AS4_09510	ENOG41060BG	Tetr family transcriptional regulator
AS4_09530	ENOG4106YT9	Enoyl-CoA hydratase
AS4_09560	ENOG4105D05	Receptor
AS4_09620	ENOG4105C85	amino acid
AS4_09630	ENOG4105C7F	AcnD-accessory protein PrpF
AS4_09640	ENOG4105BZU	Histidine kinase
AS4_09650	ENOG4105CTB	Polyprenyl synthetase
AS4_09680	ENOG4105D78	K07001 NTE family protein
AS4_09700	ENOG4105EYM	Major Facilitator superfamily
AS4_09710	ENOG4105DIJ	Phosphoethanolamine transferase
AS4_09730	ENOG4105DHQ	Histidine kinase
AS4_09810	ENOG4105CHR	reductase
AS4_09850	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AS4_09870	ENOG4105CHR	reductase
AS4_09910	ENOG4105K8R	UPF0145 protein
AS4_09920	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AS4_09930	ENOG4105BZS	acriflavin resistance protein
AS4_09940	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AS4_09950	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AS4_09980	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AS4_10010	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AS4_10030	ENOG4105H3G	oxidoreductase
AS4_10080	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AS4_10090	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AS4_10100	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AS4_10140	ENOG4105CHR	reductase
AS4_10160	ENOG4105CUB	amino acid
AS4_10190	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AS4_10200	ENOG4108Z43	UPF0250 protein
AS4_10210	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS4_10240	ENOG4105N14	lysine exporter protein LysE YggA
AS4_10250	ENOG4107T5V	SNARE associated Golgi
AS4_10280	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AS4_10330	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AS4_10340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AS4_10400	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AS4_10410	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS4_10420	ENOG4105C34	Pseudouridine synthase
AS4_10450	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AS4_10510	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AS4_10520	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AS4_10530	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AS4_10600	ENOG4105CSH	Transporter
AS4_10610	ENOG4105E98	transcriptional regulator DeoR family
AS4_10620	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AS4_10650	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
AS4_10660	ENOG4105CBD	Diacylglycerol kinase
AS4_10690	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AS4_10710	ENOG41080IJ	Diacylglycerol kinase
AS4_10720	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AS4_10730	ENOG4105BZS	acriflavin resistance protein
AS4_10740	ENOG4105CJW	magnesium transporter
AS4_10770	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS4_10780	ENOG4107QNR	UPF0135 protein
AS4_10790	ENOG4105C0H	protease
AS4_10820	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AS4_10830	ENOG4105C85	amino acid
AS4_10850	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AS4_10900	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AS4_10910	ENOG4108821	RND type efflux pump
AS4_10920	ENOG4107S01	Repressor protein MetJ
AS4_10940	ENOG4108IQI	permease
AS4_10950	ENOG4108IQI	permease
AS4_10960	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AS4_10970	ENOG4105EKE	dihydroorotase
AS4_11010	ENOG4105D0M	Protease HtpX homolog
AS4_11020	ENOG4105E4C	Lytic transglycosylase catalytic
AS4_11030	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AS4_11050	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AS4_11060	ENOG4108RRZ	Transcription elongation factor GreB
AS4_11090	ENOG4105E18	UPF0276 protein
AS4_11110	ENOG4108WQI	RNA Polymerase
AS4_11160	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AS4_11190	ENOG4105DHQ	Histidine kinase
AS4_11230	ENOG4105D05	Receptor
AS4_11250	ENOG4108SF5	RNA Polymerase
AS4_11270	ENOG4105CNM	Receptor
AS4_11280	ENOG4105CSH	Transporter
AS4_11310	ENOG4105CNM	Receptor
AS4_11320	ENOG4108WUH	Transcriptional regulator, TetR family
AS4_11420	ENOG4105CW0	outer membrane usher protein
AS4_11460	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AS4_11470	ENOG4105X0I	Fimbrial
AS4_11520	ENOG4105EVZ	LysR family transcriptional regulator
AS4_11530	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AS4_11540	ENOG4105C26	Dehydrogenase
AS4_11560	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
AS4_11580	ENOG4108M66	Involved in regulation of length and mediation of adhesion of SfmA fimbriae (but not necessary for the production of fimbriae). Seems to be mannose binding adhesin (By similarity)
AS4_11590	ENOG4105CW0	outer membrane usher protein
AS4_11600	ENOG4108AF8	Chaperone
AS4_11620	ENOG4108WDE	Fimbrial protein
AS4_11700	ENOG4107RNU	major facilitator superfamily MFS_1
AS4_11710	ENOG4107QZF	nitrite reductase NADPH large subunit
AS4_11720	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AS4_11760	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS4_11780	ENOG4108ZAF	Molybdopterin
AS4_11790	ENOG4107HP6	Transcriptional regulator
AS4_11800	ENOG4107QP7	CoA-transferase subunit A
AS4_11810	ENOG4107QNJ	CoA-transferase subunit B
AS4_11820	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_11830	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
AS4_11840	ENOG4105F2Z	3-oxoadipate enol-lactonase
AS4_11850	ENOG4105D2S	major facilitator superfamily
AS4_11860	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AS4_11870	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
AS4_11880	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
AS4_11890	ENOG4105FF2	Type I DHQase
AS4_11900	ENOG4106JPM	3-dehydroshikimate dehydratase
AS4_11910	ENOG4105TW1	Carbohydrate-selective porin OprB
AS4_11920	ENOG4105DZG	Dehydrogenase
AS4_11970	ENOG4105GR3	Histidine kinase
AS4_12000	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AS4_12020	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AS4_12030	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
AS4_12040	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
AS4_12050	ENOG4105C08	Histidine kinase
AS4_12060	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
AS4_12100	ENOG4105ENX	hydrolase
AS4_12110	ENOG410642W	LysR family Transcriptional regulator
AS4_12240	ENOG4107RAQ	aminopeptidase
AS4_12260	ENOG4105D0A	hydroxylase
AS4_12270	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AS4_12290	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AS4_12320	ENOG4105W4M	Transport-associated protein
AS4_12360	ENOG4107RZZ	dna polymerase iii epsilon subunit
AS4_12370	ENOG4105E9H	Lytic Murein transglycosylase
AS4_12390	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AS4_12400	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AS4_12410	ENOG4108JQ5	ABC transporter
AS4_12470	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AS4_12480	ENOG4105CE9	30S ribosomal protein S2
AS4_12490	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AS4_12510	ENOG4105ECQ	AraC Family Transcriptional Regulator
AS4_12560	ENOG4107ARF	
AS4_12600	ENOG4105CVE	Lytic murein transglycosylase
AS4_12610	ENOG4105CNI	cell division protein FtsW
AS4_12640	ENOG4105E3A	(ABC) transporter
AS4_12650	ENOG4105DA5	(ABC) transporter
AS4_12660	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AS4_12670	ENOG4105MEW	serine threonine protein phosphatase
AS4_12780	ENOG4105VZ8	Transcriptional regulator
AS4_13010	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AS4_13040	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AS4_13080	ENOG4105C2W	permease
AS4_13100	ENOG4108MEJ	flavin reductase domain protein
AS4_13120	ENOG4108ETY	sodium dicarboxylate symporter
AS4_13150	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AS4_13180	ENOG4105DP0	ferredoxin-NADP reductase
AS4_13190	ENOG4108R96	Methyltransferase, YaeB family
AS4_13230	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AS4_13320	ENOG4107QHF	type ii secretion system protein e
AS4_13330	ENOG4105H4F	exported protein
AS4_13350	ENOG4105DHQ	Histidine kinase
AS4_13370	ENOG4105M6F	mutator MutT protein
AS4_13390	ENOG4105BZ4	penicillin-binding protein
AS4_13400	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AS4_13410	ENOG4105VUT	cytoplasmic protein
AS4_13430	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AS4_13440	ENOG4105CK2	sodium dicarboxylate symporter
AS4_13460	ENOG4108S2Y	peptide Chain Release factor
AS4_13480	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AS4_13510	ENOG4107QS8	(LipO)protein
AS4_13520	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AS4_13550	ENOG4105EA8	2-Nitropropane dioxygenase
AS4_13650	ENOG4105D3R	alkyl hydroperoxide reductase
AS4_13660	ENOG4105CQ7	ATP-dependent helicase
AS4_13730	ENOG4105D5K	Hemolysin activator protein
AS4_13740	ENOG4105CZE	histidine utilization repressor
AS4_13750	ENOG41090B9	response to stress
AS4_13780	ENOG4105C85	amino acid
AS4_13800	ENOG41088SP	formiminoglutamate hydrolase
AS4_13810	ENOG4105D82	Glutamate dehydrogenase
AS4_13850	ENOG4105BZU	Histidine kinase
AS4_13870	ENOG4105F95	Monooxygenase
AS4_13880	ENOG4108IXY	short-chain dehydrogenase reductase
AS4_13920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AS4_13930	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
AS4_13970	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AS4_13990	ENOG4105C02	permease
AS4_14080	ENOG4108JU3	Alkyl hydroperoxide reductase
AS4_14090	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AS4_14110	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AS4_14120	ENOG4105CFP	Peptidase U32
AS4_14140	ENOG41082YX	Transcriptional regulator, arsr family
AS4_14150	ENOG4105D6J	arsenicaL-resistance protein
AS4_14160	ENOG4105W1Y	Transcriptional regulator
AS4_14230	ENOG4105D3G	Pseudouridine synthase
AS4_14240	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AS4_14250	ENOG4108IQE	Amp-dependent synthetase and ligase
AS4_14350	ENOG4105GAV	receptor
AS4_14370	ENOG4108JPW	Aminotransferase
AS4_14380	ENOG4105DY8	decarboxylase
AS4_14400	ENOG4108Z4U	Ferredoxin
AS4_14430	ENOG4105DFP	Integrase
AS4_14480	ENOG4107RGH	Aldehyde dehydrogenase
AS4_14490	ENOG4105EG6	Saccharopine dehydrogenase
AS4_14520	ENOG4105CH6	catalase
AS4_14530	ENOG4105D52	delta-aminolevulinic acid dehydratase
AS4_14580	ENOG4108Z6Z	Transcriptional regulator
AS4_14600	ENOG4108R0M	Aminoglycoside
AS4_14630	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_14640	ENOG4105CHR	reductase
AS4_14650	ENOG4108JU7	Transcriptional regulator
AS4_14710	ENOG4105K56	Transcriptional regulator
AS4_14750	ENOG4105X0I	Fimbrial
AS4_14780	ENOG4105X0I	Fimbrial
AS4_14800	ENOG4108WQH	regulatoR
AS4_14810	ENOG4105BZU	Histidine kinase
AS4_14840	ENOG4107QYX	exodeoxyribonuclease v alpha
AS4_14850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS4_14860	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AS4_14870	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AS4_14910	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AS4_14920	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AS4_14930	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AS4_14940	ENOG4105E0C	molybdate abc transporter
AS4_14950	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AS4_14960	ENOG4105F7F	Chaperone
AS4_14980	ENOG4105D5K	Hemolysin activator protein
AS4_14990	ENOG41090Q8	at two internal lysine residues, thereby converting it to the active toxin. The acyl donor is ACP
AS4_15000	ENOG4105CKT	filamentous hemagglutinin
AS4_15010	ENOG4105CKT	filamentous hemagglutinin
AS4_15130	ENOG4108J1Q	
AS4_15140	ENOG4105F7P	transcriptional regulator AsnC family
AS4_15160	ENOG4105C85	amino acid
AS4_15170	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AS4_15270	ENOG4105F57	Anthranilate dioxygenase reductase
AS4_15280	ENOG4108YS2	small subunit
AS4_15290	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
AS4_15320	ENOG4105JHE	Major Facilitator Superfamily
AS4_15350	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS4_15370	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AS4_15400	ENOG4105FUY	alpha subunit
AS4_15460	ENOG4105F11	amine oxidase
AS4_15480	ENOG4105C26	Dehydrogenase
AS4_15500	ENOG4105F2Z	3-oxoadipate enol-lactonase
AS4_15510	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_15520	ENOG4107QNJ	CoA-transferase subunit B
AS4_15530	ENOG4107QP7	CoA-transferase subunit A
AS4_15540	ENOG4105NN7	muconolactone delta-isomerase
AS4_15550	ENOG4105DTQ	mandelate racemase muconate lactonizing
AS4_15560	ENOG4108KB2	LysR family Transcriptional regulator
AS4_15570	ENOG4108MZY	
AS4_15580	ENOG4108MR5	
AS4_15590	ENOG410626B	catechol 1,2-dioxygenase
AS4_15600	ENOG4105EPF	Outer membrane porin
AS4_15620	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS4_15630	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS4_15650	ENOG41067MG	lrgb family
AS4_15700	ENOG4105CNN	ABC, transporter
AS4_15740	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AS4_15760	ENOG4105E6M	Sulphatase-modifying factor protein
AS4_15770	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AS4_15810	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AS4_15820	ENOG4107RGD	Major Facilitator superfamily
AS4_15830	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_15840	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AS4_15870	ENOG4105EA8	2-Nitropropane dioxygenase
AS4_15880	ENOG4105EQ0	Major Facilitator superfamily
AS4_15900	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_15910	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS4_15930	ENOG4105E39	Enoyl-CoA hydratase
AS4_15940	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_15950	ENOG4107RGD	Major Facilitator superfamily
AS4_15960	ENOG4107QP7	CoA-transferase subunit A
AS4_15970	ENOG4107QNJ	CoA-transferase subunit B
AS4_15990	ENOG4105EQ0	Major Facilitator superfamily
AS4_16010	ENOG4105CSU	acyl-Coa dehydrogenase
AS4_16020	ENOG4108UKI	Enoyl-CoA hydratase
AS4_16040	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
AS4_16050	ENOG4105DTD	Dehydrogenase
AS4_16060	ENOG4105CY2	Citrate transporter
AS4_16070	ENOG4105F04	LysR family Transcriptional regulator
AS4_16090	ENOG4107QNJ	CoA-transferase subunit B
AS4_16100	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_16120	ENOG4105CNV	Aldolase
AS4_16130	ENOG4105DUU	IucA IucC family protein
AS4_16150	ENOG4105DJU	Siderophore biosynthesis protein
AS4_16160	ENOG4105CIF	Ornithine Cyclodeaminase
AS4_16180	ENOG4105CS6	Rhs element vgr protein
AS4_16190	ENOG4105CNA	YD repeat protein
AS4_16210	ENOG4105CNA	YD repeat protein
AS4_16320	ENOG4105EJC	lysr family transcriptional regulator
AS4_16330	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AS4_16340	ENOG4105C94	Transporter
AS4_16360	ENOG4105DVW	rieske (2Fe-2S)
AS4_16370	ENOG4105C26	Dehydrogenase
AS4_16380	ENOG4105E3J	oxidoreductase
AS4_16410	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AS4_16450	ENOG4105EUV	Phenol 2-monooxygenase
AS4_16490	ENOG4105GR3	Histidine kinase
AS4_16500	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AS4_16510	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AS4_16520	ENOG4105BZS	acriflavin resistance protein
AS4_16540	ENOG4108YNN	Heme oxygenase
AS4_16550	ENOG4105WD1	Membrane
AS4_16580	ENOG4108SF5	RNA Polymerase
AS4_16670	ENOG4105CHM	Aminotransferase
AS4_16690	ENOG4105BZU	Histidine kinase
AS4_16700	ENOG4105BZU	Histidine kinase
AS4_16720	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AS4_16740	ENOG4105DTR	rard protein
AS4_16800	ENOG4105ECR	NmrA family
AS4_16810	ENOG4105KVH	Transcriptional regulator
AS4_16830	ENOG4107QTF	adenylosuccinate lyase
AS4_16840	ENOG41075W9	High frequency lysogenization protein HflD homolog
AS4_16880	ENOG4108Z0R	Transferase
AS4_16890	ENOG4105DZ1	carboxypeptidase
AS4_16940	ENOG4105JQN	Transcriptional regulator
AS4_16950	ENOG4105C8Y	Acetylornithine aminotransferase
AS4_16960	ENOG4105M2J	Glutaredoxin
AS4_16970	ENOG4105DAN	ATP-dependent protease
AS4_17000	ENOG4105DHU	Bile acid
AS4_17040	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AS4_17050	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AS4_17060	ENOG4105D22	carbon starvation protein
AS4_17070	ENOG4105VCD	cytoplasmic protein
AS4_17090	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AS4_17110	ENOG4105F8C	transglutaminase domain-containing protein
AS4_17590	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS4_17820	ENOG4105D05	Receptor
AS4_17910	ENOG4105BZS	acriflavin resistance protein
AS4_17950	ENOG4105C7N	Xanthine uracil vitamin C permease
AS4_17960	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AS4_17980	ENOG4105CPW	cytochrome b561
AS4_18010	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AS4_18030	ENOG4105CFH	Aspartokinase
AS4_18070	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AS4_18110	ENOG4105EW9	transcriptional regulator AsnC family
AS4_18120	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
AS4_18140	ENOG4108W2Y	isochorismatase
AS4_18170	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AS4_18180	ENOG4105ERG	peptidase m48, ste24p
AS4_18210	ENOG4105CPC	Aldo Keto reductase
AS4_18220	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AS4_18230	ENOG4108UKZ	OsmC family
AS4_18250	ENOG4105C9B	Cysteine desulfurase
AS4_18260	ENOG4105ESN	nucleotide-binding protein
AS4_18280	ENOG4105D7W	serine acetyltransferase
AS4_18300	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS4_18360	ENOG4105CXT	aspartate transcarbamylase
AS4_18370	ENOG4105CD3	dihydroorotase
AS4_18380	ENOG4105UYK	outer membrane protein a
AS4_18420	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS4_18440	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AS4_18450	ENOG4105CC0	LysR family Transcriptional regulator
AS4_18530	ENOG4107RKG	DJ-1/PfpI family
AS4_18570	ENOG4105DRR	Transcriptional regulator, GntR family
AS4_18640	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AS4_18680	ENOG4105YGK	Pfam:UPF0157
AS4_18700	ENOG4105D06	uba thif-type nad fad binding protein
AS4_18720	ENOG4105KRF	dihydroneopterin aldolase
AS4_18760	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AS4_18770	ENOG4105CFU	surface antigen
AS4_18790	ENOG4105CEY	Amp-dependent synthetase and ligase
AS4_18820	ENOG4105C5I	Dehydrogenase
AS4_18830	ENOG4105ERG	peptidase m48, ste24p
AS4_18860	ENOG4105KTH	gatB Yqey
AS4_18870	ENOG4105VCC	30S ribosomal protein S21
AS4_18920	ENOG4105CHM	Aminotransferase
AS4_18930	ENOG4105E0X	reductase
AS4_18940	ENOG4108V06	Glutathione peroxidase
AS4_18950	ENOG4106AXJ	AraC family transcriptional regulator
AS4_18980	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AS4_19010	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AS4_19050	ENOG4105ZED	uncharacterized protein ygaH
AS4_19060	ENOG4108UMN	azlc family
AS4_19110	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AS4_19120	ENOG4105C3G	gtp-binding protein
AS4_19130	ENOG4108UMI	ABC transporter, permease
AS4_19140	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AS4_19150	ENOG4105D01	(LipO)protein
AS4_19160	ENOG4105D01	(LipO)protein
AS4_19190	ENOG4107T8P	acyl-Coa dehydrogenase
AS4_19240	ENOG4107QIJ	Aconitate hydratase 2
AS4_19290	ENOG4105EW9	transcriptional regulator AsnC family
AS4_19300	ENOG4105EYW	Ion transport protein
AS4_19320	ENOG4105D6U	Sodium Glutamate Symporter
AS4_19340	ENOG4105BZU	Histidine kinase
AS4_19370	ENOG4108VMM	UPF0756 membrane protein
AS4_19380	ENOG4108Z40	Transcriptional regulator
AS4_19400	ENOG4105I08	Pseudouridine synthase
AS4_19450	ENOG4105K8N	protein family UPF0079, ATPase
AS4_19460	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AS4_19480	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AS4_19490	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AS4_19500	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AS4_19510	ENOG4105EHM	Aminoglycoside phosphotransferase
AS4_19520	ENOG4108S0S	Nucleotidyl transferase
AS4_19540	ENOG4107QJE	Chromosome Partitioning Protein
AS4_19550	ENOG4105FA0	parb-like partition protein
AS4_19570	ENOG4105SG9	biopolymer transport protein, ExbD
AS4_19580	ENOG4105BZ1	(ABC) transporter
AS4_19590	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AS4_19610	ENOG4107QRG	dna polymerase iii
AS4_19630	ENOG4105F8V	Hydrolase, tatD family
AS4_19700	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AS4_19720	ENOG4108Z6B	deaminase
AS4_19750	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AS4_19760	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AS4_19800	ENOG4108VEV	chaperone
AS4_19810	ENOG4105X0I	Fimbrial
AS4_19850	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AS4_19860	ENOG4105DWU	Membrane
AS4_19870	ENOG4107RN6	Monooxygenase
AS4_19900	ENOG4105D6Z	AFG1 family ATPase
AS4_19910	ENOG4105CZN	Potassium uptake protein
AS4_19950	ENOG4105C7B	Threonine dehydratase
AS4_19960	ENOG4105E66	phosphoriboisomerase A
AS4_20010	ENOG4105BZU	Histidine kinase
AS4_20040	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AS4_20050	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS4_20110	ENOG4105HEI	LysR family (Transcriptional regulator
AS4_20120	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS4_20140	ENOG4105ETT	transcriptional Regulator, LysR family
AS4_20150	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_20160	ENOG4107RGD	Major Facilitator superfamily
AS4_20220	ENOG4105CR4	methylisocitrate lyase
AS4_20230	ENOG4105BZN	citrate synthase
AS4_20260	ENOG4105CBC	glutamate synthase
AS4_20290	ENOG4105EZE	Cupin 4 family protein
AS4_20320	ENOG4108UHJ	MAF-like protein
AS4_20340	ENOG4105BZA	Phosphoglycerate kinase
AS4_20360	ENOG4105D2N	Aldolase
AS4_20400	ENOG4106611	bacteriocin immunity
AS4_20460	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AS4_20480	ENOG4105K4T	epimerase
AS4_20490	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AS4_20570	ENOG4108JA2	transcriptioN-repair coupling factor
AS4_20590	ENOG4105F8J	Adenylate Guanylate cyclase
AS4_20600	ENOG4108ZIT	Ferredoxin, 2FE-2S
AS4_20630	ENOG4108Z4V	iron-sulfur cluster assembly
AS4_20640	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AS4_20660	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AS4_20690	ENOG4105K70	DNA-binding protein
AS4_20700	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AS4_20710	ENOG4105E7U	AraC family transcriptional regulator
AS4_20720	ENOG4105EEF	Alkane 1-monooxygenase
AS4_20780	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AS4_20860	ENOG4105CHJ	isochorismatase hydrolase
AS4_20870	ENOG4105JQN	Transcriptional regulator
AS4_20940	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS4_20950	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS4_20960	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AS4_20980	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
AS4_21000	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
AS4_21090	ENOG4105DUM	transcriptional regulator, lysR family
AS4_21190	ENOG4106HB6	Alpha beta hydrolase
AS4_21200	ENOG4108ZX5	transcriptional regulator
AS4_21210	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS4_21230	ENOG4105ETT	transcriptional Regulator, LysR family
AS4_21240	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
AS4_21280	ENOG4105T38	integral membrane protein
AS4_21290	ENOG4105CHM	Aminotransferase
AS4_21310	ENOG4107RZC	phospholipase d
AS4_21350	ENOG4105C5H	ABC transporter
AS4_21370	ENOG4105CGF	Aromatic amino acid aminotransferase
AS4_21380	ENOG4105EV9	Alpha Beta Hydrolase
AS4_21390	ENOG4105DKK	Benzoate
AS4_21440	ENOG4105D8G	Major Facilitator superfamily
AS4_21450	ENOG41067MG	lrgb family
AS4_21460	ENOG4105VAW	lrga family
AS4_21470	ENOG4105CMU	LysR family (Transcriptional regulator
AS4_21480	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AS4_21500	ENOG4107Z3H	Transcriptional regulator, TetR family
AS4_21540	ENOG4105BZS	acriflavin resistance protein
AS4_21550	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AS4_21570	ENOG4105CHR	reductase
AS4_21580	ENOG4105ETT	transcriptional Regulator, LysR family
AS4_21600	ENOG4105C28	cystathionine
AS4_21610	ENOG4108UKI	Enoyl-CoA hydratase
AS4_21620	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_21660	ENOG4105CEY	Amp-dependent synthetase and ligase
AS4_21690	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_21730	ENOG4105VCQ	rubredoxin
AS4_21750	ENOG4108XM1	transcriptional regulator AsnC family
AS4_21770	ENOG4105D2S	major facilitator superfamily
AS4_21800	ENOG4105ENH	Sulfatase
AS4_21810	ENOG4105E6M	Sulphatase-modifying factor protein
AS4_21830	ENOG4105E0K	tonB-dependent siderophore receptor
AS4_21850	ENOG41082F9	transcriptional regulator
AS4_21860	ENOG4108IND	Tetr family transcriptional regulator
AS4_21910	ENOG4105E39	Enoyl-CoA hydratase
AS4_21920	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_21940	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS4_21950	ENOG4105C26	Dehydrogenase
AS4_21960	ENOG4107YNJ	LysR family Transcriptional regulator
AS4_21990	ENOG4105CS6	Rhs element vgr protein
AS4_22000	ENOG4105DDY	UPF0142 protein ycaO
AS4_22030	ENOG4105MUA	Resistance protein
AS4_22110	ENOG4105DAX	Pfam:DUF2983
AS4_22180	ENOG4108M24	von Willebrand factor, type A
AS4_22200	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AS4_22220	ENOG4105H3G	oxidoreductase
AS4_22230	ENOG4105KME	endoribonuclease L-psp
AS4_22270	ENOG4105C26	Dehydrogenase
AS4_22290	ENOG4105SKE	transcriptional Regulator LysR family
AS4_22300	ENOG41061H0	Monooxygenase
AS4_22310	ENOG4105DHG	Allantoate amidinohydrolase
AS4_22320	ENOG4108Z2U	ureidoglycolate hydrolase
AS4_22340	ENOG4105VT2	5-hydroxyisourate hydrolase
AS4_22400	ENOG4105CQM	Urea amidohydrolase subunit alpha
AS4_22460	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AS4_22480	ENOG41081QV	Universal stress protein
AS4_22540	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AS4_22590	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_22600	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_22610	ENOG4108MJ3	acetyltransferase
AS4_22640	ENOG4108R6W	Transcriptional regulator, ARAC family
AS4_22650	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AS4_22850	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS4_22860	ENOG4105BZU	Histidine kinase
AS4_22920	ENOG41080HT	Transcriptional regulator, arsr family
AS4_22960	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
AS4_22990	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AS4_23000	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AS4_23010	ENOG4108YZT	Adenosylcobinamide kinase
AS4_23030	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AS4_23070	ENOG4105EYM	Major Facilitator superfamily
AS4_23130	ENOG4107VFM	Dehydrogenase
AS4_23140	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AS4_23180	ENOG4105KVH	Transcriptional regulator
AS4_23190	ENOG4108Z66	YbaK ebsC protein
AS4_23200	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
AS4_23210	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AS4_23220	ENOG41077RS	Phosphatase
AS4_23250	ENOG4108HPI	phosphatidate Cytidylyltransferase
AS4_23280	ENOG4105C6T	cysteine synthase
AS4_23290	ENOG4105E55	glycerol-3-phosphate acyltransferase
AS4_23300	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AS4_23310	ENOG4108SGK	Tetr family transcriptional regulator
AS4_23370	ENOG4105CPC	Aldo Keto reductase
AS4_23380	ENOG4105EJC	lysr family transcriptional regulator
AS4_23400	ENOG4105CX6	glutaminyL-tRNA synthetase
AS4_23420	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AS4_23430	ENOG4108RCM	Nitroreductase
AS4_23480	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AS4_23490	ENOG4105CNI	cell division protein FtsW
AS4_23510	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AS4_23530	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AS4_23560	ENOG4108IJ0	Aspartate ammonia-lyase
AS4_23600	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS4_23620	ENOG4108MXF	Alpha Beta Hydrolase
AS4_23640	ENOG4105D2S	major facilitator superfamily
AS4_23650	ENOG4108KB2	LysR family Transcriptional regulator
AS4_23670	ENOG4105FUY	alpha subunit
AS4_23680	ENOG4108UKV	benzoate 1,2-dioxygenase
AS4_23690	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
AS4_23700	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
AS4_23710	ENOG4105DKK	Benzoate
AS4_23760	ENOG4105CSH	Transporter
AS4_23790	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AS4_23810	ENOG4108IJ0	Aspartate ammonia-lyase
AS4_23820	ENOG4105CK7	Sodium proline symporter
AS4_23830	ENOG4105EW9	transcriptional regulator AsnC family
AS4_23840	ENOG4105C26	Dehydrogenase
AS4_23860	ENOG410814C	multidrug resistance protein
AS4_23950	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AS4_23970	ENOG4105CD8	aminopeptidase N
AS4_24000	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AS4_24010	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS4_24020	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
AS4_24030	ENOG4108V8F	Transcriptional regulator, MarR family
AS4_24100	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS4_24120	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AS4_24130	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AS4_24150	ENOG4105BZU	Histidine kinase
AS4_24170	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AS4_24190	ENOG4105CJ2	(LipO)protein
AS4_24210	ENOG4107TSN	permease
AS4_24220	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AS4_24260	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AS4_24280	ENOG4107QSV	RmuC domain protein
AS4_24290	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AS4_24300	ENOG4105VEJ	Heat shock protein
AS4_24310	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AS4_24320	ENOG4105Y3E	Modulates RecA activity (By similarity)
AS4_24340	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS4_24360	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS4_24380	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AS4_24390	ENOG4105DZP	Membrane-associated zinc metalloprotease
AS4_24410	ENOG4105KNE	Phosphatidate cytidylyltransferase
AS4_24420	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AS4_24430	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AS4_24460	ENOG4105CUX	Signal transduction histidine kinase
AS4_24470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AS4_24490	ENOG4105VP5	Bacterial protein of unknown function (DUF937)
AS4_24520	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AS4_24530	ENOG4105CNM	Receptor
AS4_24580	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
AS4_24590	ENOG4105BZ1	(ABC) transporter
AS4_24600	ENOG4105HDD	phospholipase
AS4_24680	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AS4_24690	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AS4_24810	ENOG4105CHH	sulfate transporter
AS4_24830	ENOG4107QUV	Domain protein
AS4_24880	ENOG4105HEI	LysR family (Transcriptional regulator
AS4_24890	ENOG4107QV2	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AS4_24910	ENOG4108NIW	Leucine export protein LeuE
AS4_24920	ENOG4105DKK	Benzoate
AS4_24930	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AS4_24940	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AS4_24980	ENOG4105EE5	Membrane protein terC
AS4_25020	ENOG4107QP3	malate synthase g
AS4_25060	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AS4_25130	ENOG4105C2X	Arabinose 5-phosphate isomerase
AS4_25140	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AS4_25200	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AS4_25220	ENOG4105C28	cystathionine
AS4_25260	ENOG4105K59	histidine triad (HIT) protein
AS4_25350	ENOG4105C0A	alcohol dehydrogenase
AS4_25390	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
AS4_25410	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AS4_25460	ENOG4105CHR	reductase
AS4_25470	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_25490	ENOG4105C0A	alcohol dehydrogenase
AS4_25530	ENOG4107W6X	Transcriptional regulator
AS4_25580	ENOG4108M0I	Transcriptional regulator
AS4_25630	ENOG4108IG5	Transcriptional regulator
AS4_25640	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS4_25650	ENOG4105UCG	Domain of unknown function (DUF333)
AS4_25710	ENOG4108Z5V	transcriptional regulator, merr family
AS4_25790	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AS4_25800	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AS4_25880	ENOG41084X4	Acylphosphatase (EC 3.6.1.7)
AS4_25890	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AS4_25900	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AS4_25930	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AS4_25950	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AS4_26000	ENOG41069NU	Nitroreductase
AS4_26020	ENOG4105C1J	atp-dependent rna helicase
AS4_26050	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AS4_26060	ENOG4105M08	Membrane
AS4_26120	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
AS4_26130	ENOG4105NF4	modulator of drug activity
AS4_26150	ENOG4108K3A	Glutathione S-transferase
AS4_26160	ENOG4105CHH	sulfate transporter
AS4_26180	ENOG4105ENE	Histidine kinase
AS4_26210	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_26250	ENOG4105GVF	(ABC) transporter
AS4_26260	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AS4_26270	ENOG4105FFC	UPF0187 protein
AS4_26280	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AS4_26290	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AS4_26320	ENOG4105DEN	Luciferase family
AS4_26330	ENOG4108Z12	YiaAB two helix domain-containing protein
AS4_26410	ENOG4105E2S	oxidase) subunit II
AS4_26420	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AS4_26430	ENOG4105CCU	oxidase (Subunit III)
AS4_26440	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AS4_26500	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AS4_26520	ENOG4105CDU	Replicative dna helicase
AS4_26540	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AS4_26670	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AS4_26680	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AS4_26690	ENOG4105C12	Phosphoribosylglycinamide synthetase
AS4_26720	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AS4_26730	ENOG4108UMI	ABC transporter, permease
AS4_26810	ENOG4105C0B	DNA polymerase III (alpha subunit)
AS4_26920	ENOG4105D1Q	UPF0246 protein
AS4_26940	ENOG4105CYB	regulatoR
AS4_26950	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AS4_27000	ENOG4105E0Y	RtcB Protein
AS4_27040	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AS4_27080	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AS4_27090	ENOG4105CQC	Prephenate dehydratase
AS4_27100	ENOG4107R7Y	intracellular protease Pfpi family
AS4_27120	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_27130	ENOG4105ERU	peptidase
AS4_27140	ENOG4105CK2	sodium dicarboxylate symporter
AS4_27150	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AS4_27170	ENOG4105C8U	phosphate abc transporter
AS4_27270	ENOG4108IUZ	ABC transporter
AS4_27280	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AS4_27300	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AS4_27310	ENOG4105C2X	Arabinose 5-phosphate isomerase
AS4_27350	ENOG41064T2	transcriptional regulator, lysR family
AS4_27360	ENOG4105CHR	reductase
AS4_27380	ENOG4107T8P	acyl-Coa dehydrogenase
AS4_27420	ENOG4108UPT	UPF0178 protein
AS4_27490	ENOG4107KET	secretion protein, HlyD family
AS4_27520	ENOG4105CK2	sodium dicarboxylate symporter
AS4_27600	ENOG4108ETH	Formylglycinamide ribotide synthetase
AS4_27660	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AS4_27670	ENOG4105D05	Receptor
AS4_27680	ENOG4105CRW	Short chain fatty acid transporter
AS4_27730	ENOG4105CAU	Arsenical resistance protein, ArsH
AS4_27740	ENOG4105D6J	arsenicaL-resistance protein
AS4_27760	ENOG41082YX	Transcriptional regulator, arsr family
AS4_27880	ENOG4108T86	baseplate J family protein
AS4_27970	ENOG4105TKZ	Tail Sheath
AS4_28220	ENOG4105RDA	repressor
AS4_28300	ENOG4107YD3	Thioesterase
AS4_28310	ENOG4105E02	MotA TolQ exbB proton channel
AS4_28320	ENOG4105M8F	Biopolymer transport protein exbD tolR
AS4_28360	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AS4_28370	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AS4_28450	ENOG4105C5F	glutamine synthetase
AS4_28510	ENOG4105DFP	Integrase
AS4_28540	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AS4_28560	ENOG4105KUS	lysozyme
AS4_29040	ENOG4105DDQ	anthranilate synthase
AS4_29050	ENOG4107QYG	anthranilate phosphoribosyltransferase
AS4_29080	ENOG4105EUJ	GTP cyclohydrolase i
AS4_29120	ENOG4107FQ9	ethanolamine ammonia-lyase
AS4_29130	ENOG4105CPD	ethanolamine ammonia-lyase
AS4_29140	ENOG4107R55	ethanolamine transporter
AS4_29180	ENOG4105NX3	Membrane
AS4_29210	ENOG4105C2I	pirin domain protein
AS4_29220	ENOG4105MP9	class II Aldolase
AS4_29240	ENOG4105C2W	permease
AS4_29250	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
AS4_29260	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
AS4_29270	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AS4_29280	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
AS4_29300	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AS4_29390	ENOG4108HW3	(ABC) transporter
AS4_29410	ENOG4105MRR	Transcriptional regulator (By similarity)
AS4_29430	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AS4_29460	ENOG4105DZ2	Transcriptional regulator
AS4_29470	ENOG4105WPN	DNA integration recombination invertion protein
AS4_29480	ENOG4105SYT	Methylenetetrahydrofolate reductase
AS4_29490	ENOG41063XI	Toxic component of a toxin-antitoxin (TA) module. A
AS4_29500	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
AS4_29510	ENOG4105E0K	tonB-dependent siderophore receptor
AS4_29570	ENOG4105DDW	LysR family Transcriptional regulator
AS4_29600	ENOG4105KME	endoribonuclease L-psp
AS4_29610	ENOG4105C26	Dehydrogenase
AS4_29630	ENOG4105JSC	dimethylmenaquinone methyltransferase
AS4_29680	ENOG4105X58	receptor
AS4_29790	ENOG4108YNN	Heme oxygenase
AS4_29840	ENOG4105EUZ	Beta-lactamase domain protein
AS4_29890	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AS4_29900	ENOG4105C26	Dehydrogenase
AS4_29910	ENOG4105IKQ	hydratase
AS4_29980	ENOG4105C26	Dehydrogenase
AS4_30090	ENOG4105C85	amino acid
AS4_30100	ENOG4108FUF	Transcriptional regulator, IclR family
AS4_30110	ENOG4105CY2	Citrate transporter
AS4_30120	ENOG4105C0A	alcohol dehydrogenase
AS4_30130	ENOG4105C26	Dehydrogenase
AS4_30170	ENOG4105CW0	outer membrane usher protein
AS4_30220	ENOG4105TW1	Carbohydrate-selective porin OprB
AS4_30230	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AS4_30270	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS4_30340	ENOG4105HMI	Membrane
AS4_30390	ENOG4105E2B	Taurine dioxygenase
AS4_30400	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
AS4_30420	ENOG41090VV	Protein of unknown function (DUF2846)
AS4_30450	ENOG4105CHH	sulfate transporter
AS4_30460	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS4_30470	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AS4_30500	ENOG4107RCV	ABC transporter, permease
AS4_30510	ENOG4108IJ6	ABC transporter
AS4_30520	ENOG4105C4Y	ABC transporter
AS4_30580	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS4_30600	ENOG4105CXG	d-lactate dehydrogenase
AS4_30620	ENOG41073TP	transcriptional regulator
AS4_30630	ENOG4105DAA	L-lactate
AS4_30640	ENOG4108Q5Y	Membrane
AS4_30650	ENOG4105EGI	Transcriptional regulator
AS4_30720	ENOG4105CSH	Transporter
AS4_30730	ENOG4108R99	pseudouridine synthase
AS4_30740	ENOG4105E9K	Isocitrate dehydrogenase
AS4_30750	ENOG4107QPN	acyl-Coa dehydrogenase
AS4_30840	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AS4_30850	ENOG4105SYT	Methylenetetrahydrofolate reductase
AS4_30860	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AS4_30870	ENOG4105BZU	Histidine kinase
AS4_30880	ENOG4105C6K	Malic enzyme
AS4_30900	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AS4_30930	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AS4_30950	ENOG4105VT2	5-hydroxyisourate hydrolase
AS4_30970	ENOG4105DZ1	carboxypeptidase
AS4_30980	ENOG4105CEP	NADH dehydrogenase
AS4_30990	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AS4_31000	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AS4_31020	ENOG4105EXG	Transcriptional regulator
AS4_31050	ENOG4105CPC	Aldo Keto reductase
AS4_31060	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AS4_31070	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AS4_31080	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AS4_31100	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AS4_31110	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AS4_31130	ENOG4105C3F	Signal peptidase i
AS4_31180	ENOG4105EMU	Dehydrogenase
AS4_31190	ENOG4105CYM	Glutathione S-transferase
AS4_31210	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AS4_31250	ENOG4105DFA	alanine racemase domain protein
AS4_31280	ENOG4105CSW	GntR family transcriptional regulator
AS4_31290	ENOG4107IFA	Lipase (EC 3.1.1.3)
AS4_31320	ENOG4105E7U	AraC family transcriptional regulator
AS4_31420	ENOG4105C0H	protease
AS4_31430	ENOG4108IYU	L-aspartate oxidase
AS4_31440	ENOG4105E7U	AraC family transcriptional regulator
AS4_31500	ENOG4105HHA	aminodeoxychorismate lyase
AS4_31520	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AS4_31540	ENOG4108I5D	sulfate abc transporter
AS4_31550	ENOG4105ECW	sulfate abc transporter
AS4_31560	ENOG4108IJ6	ABC transporter
AS4_31570	ENOG4107R11	Transcriptional regulator
AS4_31610	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AS4_31620	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AS4_31650	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS4_31670	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AS4_31680	ENOG4108K3A	Glutathione S-transferase
AS4_31690	ENOG4105EXG	Transcriptional regulator
AS4_31710	ENOG4108YYC	ycei family
AS4_31730	ENOG4108UKI	Enoyl-CoA hydratase
AS4_31750	ENOG4105EGD	dinuclear metal center protein, YbgI family
AS4_31760	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS4_31790	ENOG4105C10	Electron transfer flavoprotein
AS4_31800	ENOG4105BZJ	Electron transfer flavoprotein
AS4_31810	ENOG4105N14	lysine exporter protein LysE YggA
AS4_31820	ENOG4108YXU	transcriptional regulator AsnC family
AS4_31840	ENOG4108YYQ	gCN5-related N-acetyltransferase
AS4_31870	ENOG4107VAM	peptidase, m28
AS4_31880	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AS4_31890	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AS4_31920	ENOG4105D82	Glutamate dehydrogenase
AS4_31940	ENOG4108R3D	Electron transport complex
AS4_31950	ENOG4105CSM	endonuclease III
AS4_32010	ENOG4105CJN	penicillin-binding protein
AS4_32020	ENOG4106H78	methyltransferase
AS4_32060	ENOG4108KEZ	Dehydrogenase
AS4_32070	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AS4_32090	ENOG4107QN2	dihydrolipoyl dehydrogenase
AS4_32100	ENOG4105C7S	Dehydrogenase
AS4_32110	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AS4_32120	ENOG4105E33	succinate dehydrogenase
AS4_32140	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AS4_32150	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AS4_32170	ENOG4105DUX	Transporter
AS4_32210	ENOG4105F95	Monooxygenase
AS4_32300	ENOG4105EEI	dihydropteroate synthase
AS4_32310	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AS4_32330	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AS4_32340	ENOG4105HBR	Rna-binding protein
AS4_32370	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AS4_32380	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AS4_32410	ENOG4105JQZ	Methyltransferase
AS4_32420	ENOG4105EQK	-acetyltransferase
AS4_32430	ENOG4105C85	amino acid
AS4_32450	ENOG4108RXX	maleylacetoacetate isomerase
AS4_32490	ENOG4108UKI	Enoyl-CoA hydratase
AS4_32540	ENOG4105EEQ	Na H antiporter
AS4_32550	ENOG4105CGZ	zinc metallopeptidase
AS4_32560	ENOG4105CKW	Inner membrane protein yedI
AS4_32620	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AS4_32630	ENOG4105VCQ	rubredoxin
AS4_32640	ENOG4107QZF	nitrite reductase NADPH large subunit
AS4_32660	ENOG4105C5Q	Transcriptional regulator
AS4_32700	ENOG4107U91	Rhomboid family
AS4_32710	ENOG4105CV6	ABC transporter, permease
AS4_32720	ENOG4108I0Y	(ABC) transporter
AS4_32730	ENOG4108UJV	acyl-CoA thioesterase i
AS4_32760	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
AS4_32780	ENOG4105D8T	Acyltransferase
AS4_32800	ENOG4105C03	ribonuclease
AS4_32810	ENOG4108Z03	MAF-like protein
AS4_32820	ENOG4105VQ7	Rod shape-determining protein MreD
AS4_32830	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AS4_32840	ENOG4105DFF	Rod shape-determining protein mreb
AS4_32850	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AS4_32870	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AS4_32930	ENOG4108821	RND type efflux pump
AS4_32950	ENOG4105C9K	Endothelin-converting enzyme 1
AS4_32960	ENOG4105CN8	Transcriptional regulator
AS4_33020	ENOG4105CNM	Receptor
AS4_33030	ENOG4105CKI	cobalamin synthesis protein
AS4_33050	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AS4_33070	ENOG4105CD3	dihydroorotase
AS4_33080	ENOG4107SWG	transcriptional regulator MERR family
AS4_33090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS4_33110	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AS4_33120	ENOG4105E0K	tonB-dependent siderophore receptor
AS4_33150	ENOG4105SG9	biopolymer transport protein, ExbD
AS4_33170	ENOG4105WQ5	TonB family
AS4_33180	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AS4_33200	ENOG4105GVF	(ABC) transporter
AS4_33220	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AS4_33230	ENOG4105D7T	ABC transporter
AS4_33250	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AS4_33270	ENOG4108JU7	Transcriptional regulator
AS4_33280	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AS4_33310	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AS4_33320	ENOG4105BZ1	(ABC) transporter
AS4_33330	ENOG4105BZ1	(ABC) transporter
AS4_33370	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AS4_33450	ENOG4108IPW	abc transporter atp-binding protein
AS4_33530	ENOG4105CHR	reductase
AS4_33560	ENOG4105CPP	Dehydrogenase, E1 component
AS4_33570	ENOG4107R0V	Pyruvate dehydrogenase
AS4_33580	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AS4_33610	ENOG4105C94	Transporter
AS4_33620	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
AS4_33660	ENOG4108IG5	Transcriptional regulator
AS4_33670	ENOG4105F27	Major Facilitator
AS4_33710	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS4_33730	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AS4_33740	ENOG4105FB2	class II Aldolase
AS4_33750	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AS4_33770	ENOG4105C7K	acetolactate synthase
AS4_33800	ENOG4105CHR	reductase
AS4_33830	ENOG4105DJB	Major Facilitator Superfamily
AS4_33840	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
AS4_33920	ENOG4105VJY	transcriptional regulator
AS4_33960	ENOG4105KVH	Transcriptional regulator
AS4_33990	ENOG4105CNA	YD repeat protein
AS4_34000	ENOG4105CS6	Rhs element vgr protein
AS4_34010	ENOG4108Z4X	TRANSCRIPTIONal
AS4_34030	ENOG410624X	efflux transporter, rnd family, mfp subunit
AS4_34040	ENOG4105BZS	acriflavin resistance protein
AS4_34070	ENOG4108YNN	Heme oxygenase
AS4_34090	ENOG4108SF5	RNA Polymerase
AS4_34120	ENOG4105W8I	Transcriptional regulator
AS4_34150	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AS4_34160	ENOG4105EJC	lysr family transcriptional regulator
AS4_34240	ENOG4105HSS	phospholipase C
AS4_34260	ENOG4105DY2	Paraquat-inducible protein b
AS4_34270	ENOG4105F1S	paraquat-inducible protein a
AS4_34290	ENOG4105JQN	Transcriptional regulator
AS4_34300	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AS4_34330	ENOG4108JJA	ABC, transporter
AS4_34370	ENOG4105W8I	Transcriptional regulator
AS4_34380	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AS4_34390	ENOG4105C26	Dehydrogenase
AS4_34410	ENOG4105ETS	cytosine purines uracil thiamine allantoin
AS4_34420	ENOG4105C26	Dehydrogenase
AS4_34430	ENOG4108M8W	Monooxygenase
AS4_34440	ENOG4105MXW	flavin reductase domain protein, FMN-binding
AS4_34450	ENOG4108MXF	Alpha Beta Hydrolase
AS4_34500	ENOG4105D2S	major facilitator superfamily
AS4_34530	ENOG4105E3J	oxidoreductase
AS4_34550	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
AS4_34560	ENOG4107HP6	Transcriptional regulator
AS4_34580	ENOG4105NIV	Esterase
AS4_34590	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS4_34620	ENOG4105CEB	Aspartate aminotransferase
AS4_34650	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
AS4_34660	ENOG4105DZS	Phenylacetate-CoA ligase
AS4_34670	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_34680	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AS4_34690	ENOG4108UKI	Enoyl-CoA hydratase
AS4_34700	ENOG4105E39	Enoyl-CoA hydratase
AS4_34710	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AS4_34720	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
AS4_34730	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
AS4_34740	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
AS4_34750	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
AS4_34760	ENOG4105DXM	phenylacetic acid degradation protein
AS4_34770	ENOG4105CSH	Transporter
AS4_34870	ENOG4107R3N	Filamentation induced by cAMP protein fic
AS4_34890	ENOG4105EPF	Outer membrane porin
AS4_34900	ENOG4105D2S	major facilitator superfamily
AS4_34910	ENOG4105D2S	major facilitator superfamily
AS4_34930	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AS4_34940	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AS4_34960	ENOG4105CSH	Transporter
AS4_35020	ENOG4105PV3	Inner membrane protein yqiJ
AS4_35030	ENOG4107S78	Band 7 protein
AS4_35060	ENOG4105ETS	cytosine purines uracil thiamine allantoin
AS4_35070	ENOG4105CKI	cobalamin synthesis protein
AS4_35090	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AS4_35120	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
AS4_35140	ENOG4105CNU	cell division protein FtsK
AS4_35150	ENOG4105C3M	thioredoxin reductase
AS4_35170	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AS4_35190	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
AS4_35240	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AS4_35260	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
AS4_35280	ENOG4105DEG	Vwa containing coxe family protein
AS4_35300	ENOG4108KDT	Molybdate metabolism regulator
AS4_35310	ENOG4108KDT	Molybdate metabolism regulator
AS4_35340	ENOG4108YXA	Membrane
AS4_35350	ENOG4105EXC	Acyl-transferase
AS4_35360	ENOG4105C85	amino acid
AS4_35400	ENOG4105EW9	transcriptional regulator AsnC family
AS4_35410	ENOG4107XGZ	Hydrolase
AS4_35420	ENOG4105DWF	phosphomethylpyrimidine kinase
AS4_35460	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AS4_35510	ENOG4105E3B	Multicopper oxidase
AS4_35530	ENOG4105DJV	ribulose-phosphate 3-epimerase
AS4_35550	ENOG4108M3P	Membrane
AS4_35560	ENOG4105C4W	S-formylglutathione hydrolase
AS4_35590	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AS4_35600	ENOG41072GX	Peptidase M22 Glycoprotease
AS4_35610	ENOG4108Z0R	Transferase
AS4_35620	ENOG4105P8F	nudix hydrolase
AS4_35700	ENOG4105CRQ	synthase (Component I)
AS4_35720	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AS4_35740	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AS4_35810	ENOG4105EAD	ABC transporter
AS4_35820	ENOG4105DRP	amino acid AbC transporter
AS4_35830	ENOG4105CDA	abc transporter atp-binding protein
AS4_35840	ENOG4107Y60	(LipO)protein
AS4_35860	ENOG4106B0W	Curli production assembly transport component CsgG
AS4_35910	ENOG4105F2W	methyltransferase
AS4_35970	ENOG4105K6H	D-cysteine desulfhydrase
AS4_35980	ENOG4105CBX	hi0933 family
AS4_36040	ENOG4105C2C	drug resistance transporter, Bcr CflA
AS4_36050	ENOG4105EM2	membrane
AS4_36110	ENOG4105WD1	Membrane
AS4_36170	ENOG4105CBS	Chea signal transduction histidine kinase
AS4_36180	ENOG4105C8Q	Methyl-accepting chemotaxis
AS4_36190	ENOG4108ZGA	chew protein
AS4_36200	ENOG4105M3Z	response regulator
AS4_36210	ENOG4108UNF	response regulator
AS4_36230	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AS4_36340	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AS4_36360	ENOG4105D1F	ATP-binding protein
AS4_36430	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AS4_36460	ENOG4108WS1	
AS4_36470	ENOG4108KHX	Diguanylate cyclase
AS4_36500	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AS4_36530	ENOG4105D3R	alkyl hydroperoxide reductase
AS4_36540	ENOG4109066	lysm domain bon superfamily protein
AS4_36550	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AS4_36560	ENOG4105CHR	reductase
AS4_36570	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AS4_36590	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AS4_36600	ENOG4108BPE	-transporting atpase
AS4_36610	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AS4_36650	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AS4_36730	ENOG4105KAF	membrAne
AS4_36750	ENOG4105CHU	acetyl-coa acetyltransferase
AS4_36770	ENOG4105I4A	GCN5-related N-acetyltransferase
AS4_36780	ENOG4108R6W	Transcriptional regulator, ARAC family
AS4_36790	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AS4_36800	ENOG4105TW1	Carbohydrate-selective porin OprB
AS4_36810	ENOG4105DZG	Dehydrogenase
AS4_36820	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AS4_36850	ENOG4105KWI	UPF0339 protein
AS4_36880	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AS4_36890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AS4_36910	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AS4_36930	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AS4_36940	ENOG4108UWD	Iron-storage protein
AS4_36950	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
AS4_36970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AS4_36990	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AS4_37010	ENOG4105HF0	Membrane
AS4_37070	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AS4_37100	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AS4_37200	ENOG4105CS6	Rhs element vgr protein
AS4_37300	ENOG4108UT2	hemolysin iii
AS4_37310	ENOG4105CSH	Transporter
AS4_37330	ENOG4105D3G	Pseudouridine synthase
AS4_37350	ENOG41060WC	Enoyl-CoA hydratase
AS4_37360	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_37370	ENOG4107QX3	carboxylase
AS4_37380	ENOG4105CHR	reductase
AS4_37410	ENOG4108RZE	Tetr family transcriptional regulator
AS4_37420	ENOG4105KNA	-acetyltransferase
AS4_37450	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_37460	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_37470	ENOG4105C0D	helicase
AS4_37530	ENOG4105K56	Transcriptional regulator
AS4_37540	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AS4_37550	ENOG4107QHF	type ii secretion system protein e
AS4_37600	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AS4_37620	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AS4_37670	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AS4_37700	ENOG4108WBT	adenosyltransferase
AS4_37740	ENOG4105CNG	UPF0061 protein
AS4_37760	ENOG4105MSB	protein, conserved in bacteria
AS4_37770	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS4_37780	ENOG4105EB3	Histidine kinase
AS4_37800	ENOG4105N42	UPF0307 protein
AS4_37810	ENOG41080Z8	PHOSPHOCARRIER protein
AS4_37820	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AS4_37830	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AS4_37850	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AS4_37860	ENOG4105DJ0	Poly(A) Polymerase
AS4_37880	ENOG4105DXN	mazG family
AS4_37910	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AS4_37940	ENOG4105C6T	cysteine synthase
AS4_37950	ENOG4105BZU	Histidine kinase
AS4_37960	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
AS4_37970	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AS4_37980	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AS4_38030	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AS4_38070	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AS4_38110	ENOG4105WVQ	Fe-S assembly protein IscX
AS4_38120	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
AS4_38160	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AS4_38170	ENOG4108ZP8	Acetolactate synthase small subunit
AS4_38180	ENOG4105C7K	acetolactate synthase
AS4_38230	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
AS4_38240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AS4_38250	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
AS4_38320	ENOG4105CS6	Rhs element vgr protein
AS4_38330	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AS4_38350	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AS4_38360	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AS4_38380	ENOG4105VW4	glutaredoxin 3
AS4_38460	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AS4_38470	ENOG4105W5Q	DNA repair protein (RadC
AS4_38480	ENOG4105FFC	UPF0187 protein
AS4_38550	ENOG4105C29	acyl-CoA thioesterase
AS4_38570	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AS4_38580	ENOG4107S2Z	UPF0761 membrane protein
AS4_38600	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AS4_38650	ENOG4105EQ0	Major Facilitator superfamily
AS4_38660	ENOG4107YPT	transcriptional regulator
AS4_38670	ENOG4105CT1	(ABC) transporter
AS4_38680	ENOG4107RP9	extracellular solute-binding protein, family 3
AS4_38690	ENOG4105CDA	abc transporter atp-binding protein
AS4_38700	ENOG4108HW4	amino acid AbC transporter
AS4_38710	ENOG4105EAD	ABC transporter
AS4_38740	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AS4_38760	ENOG4105DGW	oligopeptidase A
AS4_38770	ENOG4105VKU	nucleicacid-binding protein
AS4_38880	ENOG4105C1G	acyl-Coa dehydrogenase
AS4_38890	ENOG4105CT3	Monooxygenase
AS4_38900	ENOG4108ZT0	50S ribosomal protein l17
AS4_38910	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AS4_38920	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AS4_38930	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AS4_38950	ENOG41067V7	50S ribosomal protein L36
AS4_38960	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AS4_38990	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AS4_39020	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AS4_39040	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AS4_39060	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AS4_39110	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AS4_39120	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AS4_39150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AS4_39160	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AS4_39170	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AS4_39180	ENOG41089BK	Glutamine amido-transferase
AS4_39200	ENOG4105D7A	ATP-binding protein
AS4_39210	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AS4_39250	ENOG4105CK2	sodium dicarboxylate symporter
AS4_39260	ENOG4105C29	acyl-CoA thioesterase
AS4_39270	ENOG4105E55	glycerol-3-phosphate acyltransferase
AS4_39300	ENOG4105CB5	ATP-dependent DNA helicase recG
AS4_39320	ENOG4105MJ2	Competence protein
AS4_39340	ENOG4108URH	decarboxylase
AS4_39350	ENOG4105D7N	magnesium and cobalt transport protein CorA
AS4_39380	ENOG4107PE3	Mammalian cell entry related domain protein
AS4_39390	ENOG4105CY3	ABC transporter, permease
AS4_39400	ENOG4105DHJ	ABC, transporter
AS4_39410	ENOG4105C1J	atp-dependent rna helicase
AS4_39430	ENOG4105ECY	inositol monophosphatase
AS4_39440	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AS4_39450	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AS4_39470	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AS4_39510	ENOG4105CSU	acyl-Coa dehydrogenase
AS4_39530	ENOG4105CSA	Coproporphyrinogen iii oxidase
AS4_39550	ENOG4107QI1	Mate efflux family protein
AS4_39580	ENOG4105NRA	50s ribosomal protein l31 type b
AS4_39590	ENOG4105WMR	Protein CrcB homolog
AS4_39650	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AS4_39670	ENOG4105C5X	domain protein
AS4_39700	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AS4_39720	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AS4_39760	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AS4_39770	ENOG4108JU5	Magnesium and cobalt efflux protein
AS4_39780	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AS4_39790	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AS4_39820	ENOG4108VAU	general secretion pathway protein G
AS4_39830	ENOG4105D7Q	type ii secretion system
AS4_39840	ENOG4105C25	Primosomal protein n'
AS4_39880	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AS4_39890	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AS4_39910	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
AS4_39920	ENOG4105Z2P	Protein of unknown function (DUF465)
AS4_39930	ENOG4107QUT	magnesium and cobalt transport protein CorA
AS4_39940	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AS4_39970	ENOG4107QYX	exodeoxyribonuclease v alpha
AS4_39980	ENOG4107QKA	exodeoxyribonuclease V beta
AS4_39990	ENOG4105DSY	exodeoxyribonuclease V, gamma
AS4_40030	ENOG4105CSP	Major Facilitator Superfamily
AS4_40040	ENOG4108UAU	isochorismatase
AS4_40050	ENOG4105RE0	Asp Glu hydantoin racemase
AS4_40070	ENOG4105MSY	salicylate hydroxylase
AS4_40090	ENOG4108VHT	MarR family transcriptional regulator
AS4_40100	ENOG4105CSR	polyphosphate kinase 2
AS4_40140	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AS4_40170	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AS4_40220	ENOG4105D65	subunit l
AS4_40230	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AS4_40240	ENOG4107R4Z	monovalent cation h antiporter subunit d
AS4_40250	ENOG4105SC1	monovalent cation H antiporter subunit E
AS4_40260	ENOG4105W4C	monovalent cation H antiporter subunit F
AS4_40270	ENOG4105KJM	monovalent cation h antiporter subunit g
AS4_40280	ENOG4108R6K	riboflavin synthase, subunit alpha
AS4_40300	ENOG4105KVH	Transcriptional regulator
AS4_40310	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
AS4_40320	ENOG4105BZ8	glutamate synthase
AS4_40330	ENOG4105CBC	glutamate synthase
AS4_40380	ENOG4105E4G	Type IV pilus
AS4_40430	ENOG4108JQC	penicillin-binding protein 1A
AS4_40440	ENOG4105DHI	Methyltransferase
AS4_40450	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AS4_40460	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AS4_40470	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AS4_40480	ENOG4105CJN	penicillin-binding protein
AS4_40490	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AS4_40520	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AS4_40540	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AS4_40560	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AS4_40650	ENOG4105PDP	Short chain dehydrogenase
AS4_40680	ENOG4105EQ2	LysR family Transcriptional regulator
AS4_40710	ENOG4105W1Y	Transcriptional regulator
AS4_40740	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AS4_40750	ENOG4105E0F	Histidine kinase
AS4_40760	ENOG4105CYC	Transferase
AS4_40830	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AS4_40890	ENOG410631K	Membrane
AS4_40920	ENOG4105CUV	Homoserine Kinase
AS4_40950	ENOG4105C5H	ABC transporter
AS4_40990	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AS4_41040	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AS4_41050	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AS4_41060	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AS4_41080	ENOG4105CNI	cell division protein FtsW
AS4_41100	ENOG4105DQR	SNARE associated Golgi
AS4_41120	ENOG4105DVP	Adenine-specific
AS4_41130	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AS4_41150	ENOG4105BZU	Histidine kinase
AS4_41160	ENOG4108YZA	Nitrogen regulatory protein pii
AS4_41180	ENOG4105C0P	Mg chelatase subunit ChlI
AS4_41200	ENOG4108YYD	acetyltransferase
AS4_41240	ENOG41090KI	Outer membrane porin
AS4_41250	ENOG4105F0N	pyrophosphate phospho-hydrolase
AS4_41280	ENOG4105CEY	Amp-dependent synthetase and ligase
AS4_41290	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AS4_41310	ENOG41079KZ	Major Facilitator Superfamily
AS4_41330	ENOG4105EN6	Membrane
AS4_41340	ENOG4105K5B	UPF0225 protein
AS4_41350	ENOG4105EE5	Membrane protein terC
AS4_41360	ENOG4108URH	decarboxylase
AS4_41370	ENOG4105RA2	Membrane
AS4_41390	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AS4_41410	ENOG4105BZU	Histidine kinase
AS4_41420	ENOG4108HWY	Beta-lactamase
AS4_41440	ENOG4105C94	Transporter
AS4_41460	ENOG4107QN1	sodium solute
AS4_41470	ENOG41062QD	Membrane
AS4_41480	ENOG4105BZU	Histidine kinase
AS4_41540	ENOG4105Y7M	Transcriptional regulator, TetR family
AS4_41610	ENOG4108WZM	domain protein
AS4_41620	ENOG4105C79	DNA protecting protein DprA
AS4_41630	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AS4_41650	ENOG4108IND	Tetr family transcriptional regulator
AS4_41660	ENOG4107RTG	Major Facilitator superfamily
AS4_41700	ENOG4108V06	Glutathione peroxidase
AS4_41770	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AS4_41790	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AS4_41820	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AS4_41850	ENOG4105NXV	High-affinity zinc uptake system protein
AS4_41870	ENOG4105FDK	ABC transporter
AS4_41880	ENOG4105FAV	ABC, transporter
AS4_41890	ENOG4108NIW	Leucine export protein LeuE
AS4_41910	ENOG4105EZR	dyp-type peroxidase family protein
AS4_41960	ENOG4107R1I	NAD-dependent malic enzyme
AS4_42020	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AS4_42030	ENOG4105EB3	Histidine kinase
AS4_42040	ENOG4105CT7	inner membrane cred family protein
AS4_42080	ENOG4105CCT	upf0313 protein
AS4_42090	ENOG4105D94	Major Facilitator Superfamily
AS4_42110	ENOG4108UZX	fmn reductase
AS4_42120	ENOG4105FBW	Monooxygenase
AS4_42140	ENOG4107T8P	acyl-Coa dehydrogenase
AS4_42150	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AS4_42170	ENOG4105D64	Mechanosensitive ion channel
AS4_42190	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AS4_42200	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AS4_42220	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
AS4_42260	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AS4_42270	ENOG4108VBZ	doxx family
AS4_42280	ENOG4105DQR	SNARE associated Golgi
AS4_42300	ENOG4107QJE	Chromosome Partitioning Protein
AS4_42320	ENOG4105M85	Bola protein
AS4_42370	ENOG4107QKV	phosphomannomutase
AS4_42400	ENOG4105CMR	udp-glucose 4-epimerase
AS4_42420	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AS4_42430	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AS4_42440	ENOG4105D3Q	Sugar transferase
AS4_42470	ENOG4108UW5	maltose o-acetyltransferase
AS4_42480	ENOG4105K64	Glycosyl transferase, family 2
AS4_42550	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AS4_42570	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AS4_42590	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AS4_42600	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AS4_42620	ENOG4105DAY	polysaccharide export protein
AS4_42640	ENOG4105D75	Capsular exopolysaccharide family
AS4_42650	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS4_42660	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AS4_42670	ENOG4105CJR	Integral membrane protein (MviN
AS4_42680	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AS4_42690	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AS4_42730	ENOG4105HSS	phospholipase C
AS4_42740	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AS4_42810	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AS4_42820	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AS4_42840	ENOG4105UBK	short-chain dehydrogenase reductase
AS4_42890	ENOG4107QZM	n-acetylglutamate synthase
AS4_42900	ENOG4105GVF	(ABC) transporter
AS4_42910	ENOG4105GVF	(ABC) transporter
AS4_42920	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
AS4_42930	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AS4_42940	ENOG4108VM9	ABC, transporter
AS4_42950	ENOG4108W9H	Tetr family transcriptional regulator
AS4_42990	ENOG4105CDV	Ompa motb domain protein
AS4_43100	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AS4_43200	ENOG4105CGH	5'-nucleotidase
AS4_43210	ENOG4105E2B	Taurine dioxygenase
AS4_43220	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AS4_43230	ENOG4108IY8	ABC, transporter
AS4_43240	ENOG4106FTQ	Taurine ABC transporter, periplasmic
AS4_43250	ENOG4108821	RND type efflux pump
AS4_43310	ENOG4105CFG	Acts as a chaperone (By similarity)
AS4_43380	ENOG4105CVE	Lytic murein transglycosylase
AS4_43400	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AS4_43410	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AS4_43450	ENOG4105DFU	Cell wall formation (By similarity)
AS4_43480	ENOG410830R	acetyltransferase
AS4_43490	ENOG4105F27	Major Facilitator
AS4_43530	ENOG4105DU1	integral membrane protein, terc
AS4_43550	ENOG4107QUY	Guanine deaminase
AS4_43560	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AS4_43570	ENOG4105Y3U	Transglycosylase-associated protein
AS4_43580	ENOG4105T95	Thiol disulfide interChange protein
AS4_43590	ENOG4105PGM	cation diffusion facilitator family transporter
AS4_43640	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AS4_43650	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AS4_43660	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AS4_43670	ENOG4105VG0	50S ribosomal protein l34