locus-tag	class	description
Ahae5227_00010	COG0592	DNA-directed DNA polymerase activity
Ahae5227_00020	COG0187	DNA topoisomerase II activity
Ahae5227_00025	COG0586	Pfam SNARE associated Golgi protein
Ahae5227_00030	COG0488	(ABC) transporter
Ahae5227_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Ahae5227_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Ahae5227_00100	COG0471	metal ion transport
Ahae5227_00100	COG3273	potassium ion transport
Ahae5227_00110	COG1012	belongs to the aldehyde dehydrogenase family
Ahae5227_00115	COG3738	Protein conserved in bacteria
Ahae5227_00125	COG0733	neurotransmitter:sodium symporter activity
Ahae5227_00165	COG2233	PERMEase
Ahae5227_00175	COG1309	transcriptional regulator
Ahae5227_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_00195	COG0484	heat shock protein binding
Ahae5227_00210	COG2814	Major facilitator Superfamily
Ahae5227_00215	COG0656	L-ascorbic acid biosynthetic process
Ahae5227_00220	COG0583	DNA-binding transcription factor activity
Ahae5227_00235	COG1064	alcohol dehydrogenase
Ahae5227_00240	COG2818	Glycosylase
Ahae5227_00255	COG1194	a g-specific adenine glycosylase
Ahae5227_00265	COG5487	UPF0391 membrane protein
Ahae5227_00270	COG2983	Belongs to the UPF0260 family
Ahae5227_00275	COG2133	pyrroloquinoline quinone binding
Ahae5227_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Ahae5227_00295	COG1228	amidohydrolase
Ahae5227_00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Ahae5227_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ahae5227_00315	COG1335	isochorismatase
Ahae5227_00320	COG1522	sequence-specific DNA binding
Ahae5227_00350	COG0515	serine threonine protein kinase
Ahae5227_00410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Ahae5227_00420	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Ahae5227_00425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Ahae5227_00430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Ahae5227_00450	COG0560	Phosphoserine phosphatase
Ahae5227_00450	COG3830	Belongs to the UPF0237 family
Ahae5227_00495	COG1278	Cold shock
Ahae5227_00500	COG0583	DNA-binding transcription factor activity
Ahae5227_00530	COG0534	Mate efflux family protein
Ahae5227_00535	COG0436	Aminotransferase
Ahae5227_00545	COG2733	membrane
Ahae5227_00560	COG2918	glutathione biosynthetic process
Ahae5227_00575	COG3150	esterase
Ahae5227_00620	COG1247	-acetyltransferase
Ahae5227_00650	COG0625	glutathione transferase activity
Ahae5227_00675	COG1132	(ABC) transporter
Ahae5227_00695	COG1393	Belongs to the ArsC family
Ahae5227_00700	COG0708	Exodeoxyribonuclease III
Ahae5227_00715	COG0300	oxidoreductase activity
Ahae5227_00735	COG0386	Belongs to the glutathione peroxidase family
Ahae5227_00740	COG0189	ligase activity
Ahae5227_00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Ahae5227_00810	COG2119	membrane
Ahae5227_00815	COG4774	siderophore transport
Ahae5227_00820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Ahae5227_00820	COG0426	domain, Protein
Ahae5227_00845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Ahae5227_00865	COG1902	pentaerythritol trinitrate reductase activity
Ahae5227_00875	COG1519	Transferase
Ahae5227_00885	COG0668	transmembrane transport
Ahae5227_00890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ahae5227_00920	COG3706	GGDEF domain
Ahae5227_00945	COG0351	phosphomethylpyrimidine kinase
Ahae5227_00945	COG0352	thiamine-phosphate diphosphorylase activity
Ahae5227_00945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Ahae5227_00955	COG2814	Major facilitator Superfamily
Ahae5227_01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Ahae5227_01040	COG1012	belongs to the aldehyde dehydrogenase family
Ahae5227_01050	COG1335	isochorismatase
Ahae5227_01060	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
Ahae5227_01130	COG0582	viral genome integration into host DNA
Ahae5227_01140	COG3158	transport of potassium into the cell
Ahae5227_01155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Ahae5227_01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Ahae5227_01195	COG0659	secondary active sulfate transmembrane transporter activity
Ahae5227_01210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Ahae5227_01245	COG0427	acetyl-CoA hydrolase
Ahae5227_01250	COG2205	protein histidine kinase activity
Ahae5227_01255	COG0745	RESPONSE REGULATOR receiver
Ahae5227_01280	COG1028	Short-chain dehydrogenase reductase Sdr
Ahae5227_01285	COG0583	DNA-binding transcription factor activity
Ahae5227_01295	COG0789	Transcriptional regulator
Ahae5227_01315	COG4221	oxidoreductase activity
Ahae5227_01320	COG2873	o-acetylhomoserine
Ahae5227_01325	COG0488	(ABC) transporter
Ahae5227_01395	COG0833	amino acid
Ahae5227_01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Ahae5227_01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Ahae5227_01465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Ahae5227_01470	COG2226	methyltransferase
Ahae5227_01520	COG0070	glutamate synthase
Ahae5227_01520	COG0067	glutamate synthase
Ahae5227_01520	COG0069	glutamate synthase activity
Ahae5227_01525	COG0493	'glutamate synthase
Ahae5227_01535	COG1704	LemA family
Ahae5227_01540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Ahae5227_01555	COG1487	ribonuclease activity
Ahae5227_01590	COG3307	-O-antigen
Ahae5227_01610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Ahae5227_01620	COG0194	GDP metabolic process
Ahae5227_01625	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Ahae5227_01630	COG4969	Belongs to the N-Me-Phe pilin family
Ahae5227_01695	COG0228	four-way junction DNA binding
Ahae5227_01700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Ahae5227_01710	COG0335	large ribosomal subunit rRNA binding
Ahae5227_01720	COG5380	lipid catabolic process
Ahae5227_01725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Ahae5227_01750	COG0741	lytic transglycosylase activity
Ahae5227_01750	COG1196	nuclear chromosome segregation
Ahae5227_01750	COG0739	heme binding
Ahae5227_01755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ahae5227_01760	COG0277	FAD linked oxidase domain protein
Ahae5227_01775	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Ahae5227_01780	COG2249	NAD(P)H dehydrogenase (quinone) activity
Ahae5227_01800	COG1289	transmembrane transporter activity
Ahae5227_01805	COG0628	permease
Ahae5227_01810	COG1192	Involved in chromosome partitioning
Ahae5227_01820	COG2226	methyltransferase
Ahae5227_01855	COG1404	Belongs to the peptidase S8 family
Ahae5227_01865	COG2072	flavoprotein involved in K transport
Ahae5227_01925	COG3328	transposase activity
Ahae5227_01945	COG0471	metal ion transport
Ahae5227_01955	COG1983	PspC domain protein
Ahae5227_01965	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_02025	COG1127	ABC transporter
Ahae5227_02030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Ahae5227_02035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Ahae5227_02040	COG2854	intermembrane phospholipid transfer
Ahae5227_02055	COG0598	Magnesium transport protein CorA
Ahae5227_02070	COG1040	competence protein
Ahae5227_02075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Ahae5227_02090	COG2937	Belongs to the GPAT DAPAT family
Ahae5227_02095	COG1946	Acyl-CoA thioesterase
Ahae5227_02100	COG1301	dicarboxylic acid transport
Ahae5227_02120	COG1959	2 iron, 2 sulfur cluster binding
Ahae5227_02130	COG0433	COG0433 Predicted ATPase
Ahae5227_02150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Ahae5227_02170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Ahae5227_02220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Ahae5227_02300	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_02305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Ahae5227_02330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ahae5227_02355	COG0339	signal peptide processing
Ahae5227_02360	COG0557	exoribonuclease II activity
Ahae5227_02450	COG0179	Fumarylacetoacetate (FAA) hydrolase
Ahae5227_02460	COG2207	Transcriptional regulator
Ahae5227_02470	COG1295	ribonuclease BN
Ahae5227_02510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ahae5227_02540	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ahae5227_02540	COG2813	Specifically methylates the guanine in position
Ahae5227_02550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ahae5227_02555	COG4771	TonB-dependent receptor
Ahae5227_02565	COG0740	serine-type endopeptidase activity
Ahae5227_02585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Ahae5227_02585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Ahae5227_02590	COG1917	Cupin 2, conserved barrel domain protein
Ahae5227_02590	COG2207	Transcriptional regulator
Ahae5227_02595	COG0697	spore germination
Ahae5227_02610	COG0280	phosphate acetyltransferase
Ahae5227_02610	COG0857	belongs to the CobB CobQ family
Ahae5227_02615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Ahae5227_02625	COG2267	carboxylic ester hydrolase activity
Ahae5227_02645	COG0793	Belongs to the peptidase S41A family
Ahae5227_02690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Ahae5227_02700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Ahae5227_02705	COG1408	metallophosphoesterase
Ahae5227_02715	COG2199	diguanylate cyclase activity
Ahae5227_02755	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_02770	COG1309	transcriptional regulator
Ahae5227_02785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ahae5227_02805	COG2969	positive regulation of protein catabolic process
Ahae5227_02810	COG0625	glutathione transferase activity
Ahae5227_02815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Ahae5227_02820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Ahae5227_02830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Ahae5227_02835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Ahae5227_02840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Ahae5227_02855	COG2975	iron-sulfur cluster assembly
Ahae5227_02875	COG1426	Protein conserved in bacteria
Ahae5227_02910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Ahae5227_02920	COG1862	Preprotein translocase
Ahae5227_02950	COG2205	protein histidine kinase activity
Ahae5227_02950	COG0784	Response regulator, receiver
Ahae5227_02950	COG5002	protein histidine kinase activity
Ahae5227_02955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Ahae5227_02965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Ahae5227_02990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Ahae5227_02990	COG2755	lipolytic protein G-D-S-L family
Ahae5227_03025	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Ahae5227_03065	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_03070	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_03080	COG2205	protein histidine kinase activity
Ahae5227_03085	COG0745	RESPONSE REGULATOR receiver
Ahae5227_03105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Ahae5227_03125	COG2096	Adenosyltransferase
Ahae5227_03130	COG4206	TonB-dependent receptor
Ahae5227_03180	COG0285	dihydrofolate synthase activity
Ahae5227_03195	COG0450	alkyl hydroperoxide reductase
Ahae5227_03215	COG0477	Major facilitator Superfamily
Ahae5227_03220	COG1272	protein, Hemolysin III
Ahae5227_03250	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ahae5227_03250	COG1024	Enoyl-CoA hydratase
Ahae5227_03255	COG0183	Belongs to the thiolase family
Ahae5227_03265	COG2207	Transcriptional regulator
Ahae5227_03270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Ahae5227_03285	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ahae5227_03300	COG0183	Belongs to the thiolase family
Ahae5227_03310	COG2885	chlorophyll binding
Ahae5227_03310	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Ahae5227_03315	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Ahae5227_03315	COG2885	chlorophyll binding
Ahae5227_03320	COG1690	Belongs to the RtcB family
Ahae5227_03325	COG0833	amino acid
Ahae5227_03335	COG2233	PERMEase
Ahae5227_03370	COG4772	TonB-dependent receptor
Ahae5227_03380	COG0354	folic acid binding
Ahae5227_03390	COG2824	Alkylphosphonate utilization operon protein PhnA
Ahae5227_03395	COG3422	double-strand break repair
Ahae5227_03430	COG0840	transmembrane signaling receptor activity
Ahae5227_03435	COG2198	Histidine kinase
Ahae5227_03435	COG0643	Histidine kinase
Ahae5227_03435	COG2198	Histidine kinase
Ahae5227_03435	COG0643	Histidine kinase
Ahae5227_03450	COG5510	response to toxic substance
Ahae5227_03460	COG2832	Protein of unknown function (DUF454)
Ahae5227_03465	COG1376	ErfK ybiS ycfS ynhG family protein
Ahae5227_03510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Ahae5227_03520	COG1289	transmembrane transporter activity
Ahae5227_03525	COG2814	Major facilitator Superfamily
Ahae5227_03540	COG0786	glutamate:sodium symporter activity
Ahae5227_03545	COG1115	amino acid carrier protein
Ahae5227_03550	COG1752	Esterase of the alpha-beta hydrolase superfamily
Ahae5227_03555	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
Ahae5227_03590	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ahae5227_03615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ahae5227_03620	COG1077	Cell shape determining protein MreB Mrl
Ahae5227_03625	COG1792	Involved in formation and maintenance of cell shape
Ahae5227_03635	COG0424	maF-like protein
Ahae5227_03640	COG1530	ribonuclease E activity
Ahae5227_03650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Ahae5227_03660	COG0560	Phosphoserine phosphatase
Ahae5227_03700	COG1113	amino acid transport
Ahae5227_03710	COG0142	geranyltranstransferase activity
Ahae5227_03725	COG1752	Esterase of the alpha-beta hydrolase superfamily
Ahae5227_03760	COG2194	sulfuric ester hydrolase activity
Ahae5227_03765	COG0745	RESPONSE REGULATOR receiver
Ahae5227_03770	COG0642	Histidine kinase
Ahae5227_03780	COG1126	abc transporter atp-binding protein
Ahae5227_03785	COG0765	amino acid transport
Ahae5227_03790	COG0765	amino acid transport
Ahae5227_03800	COG0004	ammonium transporteR
Ahae5227_03815	COG2852	Protein conserved in bacteria
Ahae5227_03820	COG3328	transposase activity
Ahae5227_03850	COG0525	valine-tRNA ligase activity
Ahae5227_03865	COG1028	Short-chain dehydrogenase reductase Sdr
Ahae5227_03875	COG0393	Putative heavy-metal-binding
Ahae5227_03880	COG0393	Putative heavy-metal-binding
Ahae5227_03885	COG1538	Outer membrane efflux protein
Ahae5227_03895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_03900	COG0671	phosphoesterase, PA-phosphatase related
Ahae5227_03930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Ahae5227_03945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ahae5227_03945	COG1648	precorrin-2 dehydrogenase activity
Ahae5227_03950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Ahae5227_03960	COG1733	regulation of RNA biosynthetic process
Ahae5227_03970	COG0531	amino acid
Ahae5227_03985	COG0321	lipoyl(octanoyl) transferase activity
Ahae5227_04015	COG1280	lysine exporter protein (LysE YggA)
Ahae5227_04030	COG0500	methyltransferase
Ahae5227_04035	COG0586	Pfam SNARE associated Golgi protein
Ahae5227_04055	COG2009	succinate dehydrogenase
Ahae5227_04060	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Ahae5227_04065	COG1053	succinate dehydrogenase
Ahae5227_04070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Ahae5227_04090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahae5227_04115	COG2801	Transposase and inactivated derivatives
Ahae5227_04120	COG2268	Band 7 protein
Ahae5227_04125	COG1585	Membrane protein implicated in regulation of membrane protease activity
Ahae5227_04135	COG2354	Protein conserved in bacteria
Ahae5227_04140	COG2321	neutral zinc metallopeptidase
Ahae5227_04150	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_04175	COG2801	Transposase and inactivated derivatives
Ahae5227_04235	COG0110	maltose O-acetyltransferase activity
Ahae5227_04245	COG2801	Transposase and inactivated derivatives
Ahae5227_04260	COG0505	Belongs to the CarA family
Ahae5227_04285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahae5227_04300	COG2304	oxidoreductase activity
Ahae5227_04360	COG2194	sulfuric ester hydrolase activity
Ahae5227_04365	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ahae5227_04370	COG2239	Acts as a magnesium transporter
Ahae5227_04380	COG0501	Belongs to the peptidase M48B family
Ahae5227_04385	COG0739	heme binding
Ahae5227_04385	COG0741	lytic transglycosylase activity
Ahae5227_04385	COG1196	nuclear chromosome segregation
Ahae5227_04405	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Ahae5227_04410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Ahae5227_04495	COG2184	nucleotidyltransferase activity
Ahae5227_04505	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Ahae5227_04555	COG2233	PERMEase
Ahae5227_04560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Ahae5227_04565	COG0251	oxidation-reduction process
Ahae5227_04570	COG1335	isochorismatase
Ahae5227_04575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ahae5227_04580	COG0778	Nitroreductase
Ahae5227_04585	COG0596	Alpha beta hydrolase
Ahae5227_04600	COG0582	viral genome integration into host DNA
Ahae5227_04610	COG1301	dicarboxylic acid transport
Ahae5227_04645	COG0725	ABC transporter, periplasmic molybdate-binding protein
Ahae5227_04650	COG4149	molybdate abc transporter
Ahae5227_04665	COG4521	taurine ABC transporter
Ahae5227_04670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Ahae5227_04675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ahae5227_04720	COG0589	response to stress
Ahae5227_04735	COG0242	peptide deformylase activity
Ahae5227_04740	COG2852	Protein conserved in bacteria
Ahae5227_04760	COG0306	phosphate transporter
Ahae5227_04780	COG1115	amino acid carrier protein
Ahae5227_04790	COG0019	diaminopimelate decarboxylase activity
Ahae5227_04795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Ahae5227_04805	COG1280	lysine exporter protein (LysE YggA)
Ahae5227_04810	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Ahae5227_04825	COG2318	DinB family
Ahae5227_04835	COG0842	Transport permease protein
Ahae5227_04845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_04870	COG1671	Belongs to the UPF0178 family
Ahae5227_04885	COG4591	ABC-type transport system involved in lipoprotein release permease component
Ahae5227_04890	COG1136	(ABC) transporter
Ahae5227_04895	COG0658	competence protein
Ahae5227_04895	COG2333	competence protein COMEC
Ahae5227_04905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ahae5227_04905	COG0616	signal peptide processing
Ahae5227_04915	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Ahae5227_04925	COG0628	permease
Ahae5227_04990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Ahae5227_05010	COG0823	Involved in the tonB-independent uptake of proteins
Ahae5227_05030	COG0824	Thioesterase
Ahae5227_05040	COG2255	four-way junction helicase activity
Ahae5227_05060	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ahae5227_05060	COG0047	phosphoribosylformylglycinamidine synthase activity
Ahae5227_05105	COG3323	Protein of unknown function (DUF1653)
Ahae5227_05105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Ahae5227_05110	COG0778	Nitroreductase
Ahae5227_05120	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
Ahae5227_05120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Ahae5227_05120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Ahae5227_05125	COG1105	Belongs to the carbohydrate kinase PfkB family
Ahae5227_05130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ahae5227_05130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Ahae5227_05135	COG1024	Enoyl-CoA hydratase
Ahae5227_05140	COG1056	cytidyltransferase-related domain
Ahae5227_05140	COG1051	belongs to the nudix hydrolase family
Ahae5227_05145	COG0583	DNA-binding transcription factor activity
Ahae5227_05150	COG1942	4-Oxalocrotonate Tautomerase
Ahae5227_05175	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ahae5227_05190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Ahae5227_05195	COG0602	queuosine metabolic process
Ahae5227_05210	COG0583	DNA-binding transcription factor activity
Ahae5227_05215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Ahae5227_05220	COG4208	sulfate ABC transporter
Ahae5227_05225	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Ahae5227_05235	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Ahae5227_05240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Ahae5227_05245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Ahae5227_05290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ahae5227_05300	COG0481	GTPase activity
Ahae5227_05315	COG0571	ribonuclease III activity
Ahae5227_05320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Ahae5227_05335	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Ahae5227_05360	COG0436	Aminotransferase
Ahae5227_05390	COG0556	nucleotide-excision repair
Ahae5227_05395	COG3293	Transposase
Ahae5227_05445	COG1840	ABC-type Fe3 transport system, periplasmic component
Ahae5227_05450	COG3842	ATPase activity
Ahae5227_05470	COG0583	DNA-binding transcription factor activity
Ahae5227_05475	COG0596	Alpha beta hydrolase
Ahae5227_05480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ahae5227_05490	COG1773	rubredoxin
Ahae5227_05500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Ahae5227_05510	COG0175	sulfate reduction
Ahae5227_05525	COG0222	ribosome binding
Ahae5227_05530	COG1253	flavin adenine dinucleotide binding
Ahae5227_05545	COG3015	lipoprotein NlpE involved in copper resistance
Ahae5227_05575	COG0642	Histidine kinase
Ahae5227_05580	COG0745	RESPONSE REGULATOR receiver
Ahae5227_05590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ahae5227_05605	COG0640	Transcriptional regulator
Ahae5227_05630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ahae5227_05710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Ahae5227_05765	COG3586	endonuclease activity
Ahae5227_05815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Ahae5227_05825	COG3756	Protein conserved in bacteria
Ahae5227_05860	COG0517	IMP dehydrogenase activity
Ahae5227_05860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ahae5227_05865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Ahae5227_05875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Ahae5227_05880	COG1137	ATPase activity
Ahae5227_05905	COG1739	Uncharacterized protein family UPF0029
Ahae5227_05920	COG4122	O-methyltransferase activity
Ahae5227_05930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Ahae5227_06015	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Ahae5227_06055	COG0204	Acyl-transferase
Ahae5227_06060	COG4783	chaperone-mediated protein folding
Ahae5227_06080	COG1610	YqeY-like protein
Ahae5227_06150	COG1414	Transcriptional regulator
Ahae5227_06170	COG1028	Short-chain dehydrogenase reductase Sdr
Ahae5227_06180	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ahae5227_06185	COG2271	Major facilitator Superfamily
Ahae5227_06200	COG1028	Short-chain dehydrogenase reductase Sdr
Ahae5227_06215	COG0028	Belongs to the TPP enzyme family
Ahae5227_06235	COG0482	sulfurtransferase activity
Ahae5227_06250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Ahae5227_06255	COG1686	Belongs to the peptidase S11 family
Ahae5227_06275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Ahae5227_06285	COG0583	DNA-binding transcription factor activity
Ahae5227_06300	COG1067	ATP-dependent peptidase activity
Ahae5227_06320	COG0254	rRNA binding
Ahae5227_06340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Ahae5227_06345	COG1966	Carbon starvation protein
Ahae5227_06350	COG2879	small protein
Ahae5227_06355	COG0714	Associated with various cellular activities
Ahae5227_06455	COG1785	Belongs to the alkaline phosphatase family
Ahae5227_06505	COG3604	Transcriptional regulator
Ahae5227_06530	COG2144	transferase activity, transferring acyl groups
Ahae5227_06540	COG2072	flavoprotein involved in K transport
Ahae5227_06610	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
Ahae5227_06615	COG2116	formate transmembrane transporter activity
Ahae5227_06620	COG0515	serine threonine protein kinase
Ahae5227_06645	COG1741	Belongs to the pirin family
Ahae5227_06660	COG1902	pentaerythritol trinitrate reductase activity
Ahae5227_06660	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ahae5227_06670	COG0582	viral genome integration into host DNA
Ahae5227_06775	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ahae5227_06805	COG0569	domain protein
Ahae5227_06810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Ahae5227_06815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Ahae5227_06820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Ahae5227_06825	COG2205	protein histidine kinase activity
Ahae5227_06830	COG0745	RESPONSE REGULATOR receiver
Ahae5227_06835	COG0174	glutamine synthetase
Ahae5227_06875	COG2995	paraquat-inducible protein a
Ahae5227_06880	COG3008	intermembrane lipid transfer
Ahae5227_06880	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Ahae5227_06920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Ahae5227_06930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Ahae5227_06935	COG1469	GTP cyclohydrolase I activity
Ahae5227_06950	COG0523	cobalamin synthesis protein
Ahae5227_06955	COG1414	Transcriptional regulator
Ahae5227_06960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Ahae5227_06965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Ahae5227_06970	COG0183	Belongs to the thiolase family
Ahae5227_06975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Ahae5227_06980	COG0596	Alpha beta hydrolase
Ahae5227_06985	COG2271	Major facilitator Superfamily
Ahae5227_06990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ahae5227_06995	COG3485	protocatechuate 3,4-dioxygenase
Ahae5227_07000	COG3485	protocatechuate 3,4-dioxygenase
Ahae5227_07005	COG0710	3-dehydroquinate dehydratase activity
Ahae5227_07010	COG3420	alginic acid biosynthetic process
Ahae5227_07015	COG3659	wide pore channel activity
Ahae5227_07020	COG4993	Dehydrogenase
Ahae5227_07030	COG2351	hydroxyisourate hydrolase activity
Ahae5227_07035	COG2233	PERMEase
Ahae5227_07055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ahae5227_07065	COG4266	Belongs to the allantoicase family
Ahae5227_07080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ahae5227_07090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ahae5227_07105	COG0583	DNA-binding transcription factor activity
Ahae5227_07115	COG2188	Transcriptional regulator
Ahae5227_07135	COG0010	Belongs to the arginase family
Ahae5227_07140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ahae5227_07145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Ahae5227_07180	COG0243	molybdopterin cofactor binding
Ahae5227_07185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Ahae5227_07190	COG2837	iron assimilation
Ahae5227_07200	COG1538	Outer membrane efflux protein
Ahae5227_07205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ahae5227_07210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_07230	COG5002	protein histidine kinase activity
Ahae5227_07235	COG3040	lipid binding
Ahae5227_07270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ahae5227_07280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ahae5227_07290	COG2801	Transposase and inactivated derivatives
Ahae5227_07320	COG1309	transcriptional regulator
Ahae5227_07340	COG2072	flavoprotein involved in K transport
Ahae5227_07345	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Ahae5227_07350	COG1560	Kdo2-lipid A biosynthetic process
Ahae5227_07355	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Ahae5227_07360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Ahae5227_07365	COG4770	biotin carboxylase activity
Ahae5227_07370	COG0501	Belongs to the peptidase M48B family
Ahae5227_07390	COG1765	OsmC-like protein
Ahae5227_07445	COG4133	protoheme IX ABC transporter activity
Ahae5227_07475	COG0308	aminopeptidase N
Ahae5227_07480	COG1760	l-serine dehydratase
Ahae5227_07500	COG1714	RDD family
Ahae5227_07510	COG0475	glutathione-regulated potassium exporter activity
Ahae5227_07510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Ahae5227_07515	COG3135	benzoate transporter
Ahae5227_07525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Ahae5227_07530	COG0583	DNA-binding transcription factor activity
Ahae5227_07550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Ahae5227_07580	COG0316	Belongs to the HesB IscA family
Ahae5227_07585	COG0822	iron-sulfur transferase activity
Ahae5227_07610	COG0776	regulation of translation
Ahae5227_07615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ahae5227_07630	COG2137	regulation of response to DNA damage stimulus
Ahae5227_07640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Ahae5227_07645	COG1011	Hydrolase
Ahae5227_07650	COG1218	3'(2'),5'-bisphosphate nucleotidase
Ahae5227_07695	COG0268	Binds directly to 16S ribosomal RNA
Ahae5227_07700	COG0702	epimerase
Ahae5227_07705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Ahae5227_07725	COG0183	Belongs to the thiolase family
Ahae5227_07780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Ahae5227_07785	COG0583	DNA-binding transcription factor activity
Ahae5227_07790	COG0424	maF-like protein
Ahae5227_07845	COG1286	toxin biosynthetic process
Ahae5227_07885	COG2801	Transposase and inactivated derivatives
Ahae5227_07895	COG3634	alkyl hydroperoxide reductase activity
Ahae5227_07930	COG0436	Aminotransferase
Ahae5227_07935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ahae5227_07940	COG0386	Belongs to the glutathione peroxidase family
Ahae5227_07950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_07965	COG1522	sequence-specific DNA binding
Ahae5227_07975	COG0436	Aminotransferase
Ahae5227_08000	COG1253	flavin adenine dinucleotide binding
Ahae5227_08005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ahae5227_08015	COG0012	GTP binding
Ahae5227_08020	COG2011	ABC-type metal ion transport system permease component
Ahae5227_08025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Ahae5227_08070	COG2195	Cleaves the N-terminal amino acid of tripeptides
Ahae5227_08080	COG3550	peptidyl-serine autophosphorylation
Ahae5227_08125	COG2363	Small membrane protein
Ahae5227_08145	COG0513	Belongs to the DEAD box helicase family
Ahae5227_08155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ahae5227_08170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Ahae5227_08180	COG1192	Involved in chromosome partitioning
Ahae5227_08185	COG1475	DNA binding
Ahae5227_08190	COG0811	peptide transport
Ahae5227_08200	COG1132	(ABC) transporter
Ahae5227_08205	COG1663	tetraacyldisaccharide 4'-kinase activity
Ahae5227_08230	COG0084	hydrolase, TatD family'
Ahae5227_08300	COG0776	regulation of translation
Ahae5227_08315	COG2431	L-lysine efflux transmembrane transporter activity
Ahae5227_08330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Ahae5227_08335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Ahae5227_08385	COG0024	Methionine aminopeptidase
Ahae5227_08390	COG0583	DNA-binding transcription factor activity
Ahae5227_08400	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Ahae5227_08405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ahae5227_08410	COG0517	IMP dehydrogenase activity
Ahae5227_08410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ahae5227_08435	COG0552	protein localization to endoplasmic reticulum
Ahae5227_08465	COG4890	Cyd operon protein YbgT
Ahae5227_08470	COG1294	oxidase, subunit
Ahae5227_08495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ahae5227_08515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ahae5227_08520	COG0569	domain protein
Ahae5227_08525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ahae5227_08530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Ahae5227_08575	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Ahae5227_08585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Ahae5227_08590	COG0542	response to heat
Ahae5227_08600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Ahae5227_08605	COG2267	carboxylic ester hydrolase activity
Ahae5227_08615	COG1902	pentaerythritol trinitrate reductase activity
Ahae5227_08615	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ahae5227_08650	COG0148	phosphopyruvate hydratase activity
Ahae5227_08655	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Ahae5227_08715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Ahae5227_08740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Ahae5227_08755	COG1802	Transcriptional regulator
Ahae5227_08770	COG2207	Transcriptional regulator
Ahae5227_08775	COG1063	alcohol dehydrogenase
Ahae5227_08785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Ahae5227_08850	COG1944	ATP diphosphatase activity
Ahae5227_08870	COG1522	sequence-specific DNA binding
Ahae5227_08885	COG0439	Biotin carboxylase
Ahae5227_08895	COG0864	Transcriptional regulator
Ahae5227_08900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ahae5227_08910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ahae5227_08915	COG1595	DNA-templated transcription, initiation
Ahae5227_08975	COG0583	DNA-binding transcription factor activity
Ahae5227_08990	COG4770	biotin carboxylase activity
Ahae5227_08995	COG1024	Enoyl-CoA hydratase
Ahae5227_09000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ahae5227_09005	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_09010	COG1309	transcriptional regulator
Ahae5227_09015	COG0318	PFAM AMP-dependent synthetase and ligase
Ahae5227_09030	COG2814	Major facilitator Superfamily
Ahae5227_09050	COG0583	DNA-binding transcription factor activity
Ahae5227_09060	COG4774	siderophore transport
Ahae5227_09135	COG4584	PFAM Integrase catalytic
Ahae5227_09135	COG2390	Transcriptional regulator
Ahae5227_09140	COG1484	DNA-dependent DNA replication
Ahae5227_09305	COG3706	GGDEF domain
Ahae5227_09325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahae5227_09345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Ahae5227_09390	COG0537	adenosine 5'-monophosphoramidase activity
Ahae5227_09420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ahae5227_09440	COG0730	response to heat
Ahae5227_09445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Ahae5227_09455	COG4771	TonB-dependent receptor
Ahae5227_09475	COG0406	alpha-ribazole phosphatase activity
Ahae5227_09480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Ahae5227_09500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Ahae5227_09515	COG2223	nitrite transmembrane transporter activity
Ahae5227_09560	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_09565	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_09570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahae5227_09575	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ahae5227_09580	COG2207	Transcriptional regulator
Ahae5227_09585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ahae5227_09620	COG0575	Belongs to the CDS family
Ahae5227_09625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Ahae5227_09635	COG0528	UMP kinase activity
Ahae5227_09645	COG3852	Histidine kinase
Ahae5227_09655	COG1309	transcriptional regulator
Ahae5227_09700	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Ahae5227_09720	COG0697	spore germination
Ahae5227_09725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Ahae5227_09735	COG0303	'Molybdopterin
Ahae5227_09740	COG0315	cyclic pyranopterin monophosphate synthase activity
Ahae5227_09740	COG0521	Mo-molybdopterin cofactor biosynthetic process
Ahae5227_09755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Ahae5227_09760	COG0243	molybdopterin cofactor binding
Ahae5227_09775	COG0243	molybdopterin cofactor binding
Ahae5227_09780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ahae5227_09785	COG2146	nitrite reductase [NAD(P)H] activity
Ahae5227_09785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ahae5227_09790	COG2223	nitrite transmembrane transporter activity
Ahae5227_09800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ahae5227_09800	COG1116	anion transmembrane transporter activity
Ahae5227_09815	COG0439	Biotin carboxylase
Ahae5227_09830	COG2814	Major facilitator Superfamily
Ahae5227_09840	COG0069	glutamate synthase activity
Ahae5227_09860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Ahae5227_09875	COG1454	alcohol dehydrogenase
Ahae5227_09885	COG0824	Thioesterase
Ahae5227_09895	COG2850	peptidyl-arginine hydroxylation
Ahae5227_09920	COG0640	Transcriptional regulator
Ahae5227_09945	COG0668	transmembrane transport
Ahae5227_09965	COG1132	(ABC) transporter
Ahae5227_09985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Ahae5227_09995	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Ahae5227_09995	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Ahae5227_09995	COG0506	proline dehydrogenase activity
Ahae5227_10010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Ahae5227_10020	COG3698	Phosphodiester glycosidase
Ahae5227_10035	COG3153	acetyltransferase
Ahae5227_10040	COG2353	YceI-like domain
Ahae5227_10055	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Ahae5227_10060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Ahae5227_10085	COG1278	Cold shock
Ahae5227_10090	COG1278	Cold shock
Ahae5227_10110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Ahae5227_10110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Ahae5227_10145	COG3539	Fimbrial protein
Ahae5227_10215	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Ahae5227_10235	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_10255	COG3501	Rhs element vgr protein
Ahae5227_10260	COG3139	Protein of unknown function (DUF1315)
Ahae5227_10265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Ahae5227_10270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Ahae5227_10280	COG0494	nUDIX hydrolase
Ahae5227_10290	COG0642	Histidine kinase
Ahae5227_10305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Ahae5227_10310	COG1720	tRNA m6t6A37 methyltransferase activity
Ahae5227_10345	COG0583	DNA-binding transcription factor activity
Ahae5227_10350	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Ahae5227_10360	COG2814	Major facilitator Superfamily
Ahae5227_10365	COG4607	ABC-type enterochelin transport system periplasmic component
Ahae5227_10370	COG4604	ABC transporter, ATP-binding protein
Ahae5227_10375	COG4605	iron ion homeostasis
Ahae5227_10380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ahae5227_10390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ahae5227_10395	COG0471	metal ion transport
Ahae5227_10425	COG0729	surface antigen
Ahae5227_10450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Ahae5227_10470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Ahae5227_10480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Ahae5227_10565	COG3659	wide pore channel activity
Ahae5227_10575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Ahae5227_10585	COG0583	DNA-binding transcription factor activity
Ahae5227_10590	COG1131	(ABC) transporter
Ahae5227_10595	COG0842	Transport permease protein
Ahae5227_10610	COG0772	Belongs to the SEDS family
Ahae5227_10615	COG2951	lytic endotransglycosylase activity
Ahae5227_10640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Ahae5227_10655	COG1643	Atp-dependent helicase
Ahae5227_10660	COG0450	alkyl hydroperoxide reductase
Ahae5227_10670	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ahae5227_10690	COG3634	alkyl hydroperoxide reductase activity
Ahae5227_10710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Ahae5227_10725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Ahae5227_10735	COG0531	amino acid
Ahae5227_10740	COG4303	Ethanolamine ammonia lyase large subunit
Ahae5227_10745	COG4302	ethanolamine ammonia-lyase activity
Ahae5227_10750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ahae5227_10750	COG0519	Catalyzes the synthesis of GMP from XMP
Ahae5227_10755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ahae5227_10765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ahae5227_10775	COG2249	NAD(P)H dehydrogenase (quinone) activity
Ahae5227_10785	COG0697	spore germination
Ahae5227_10790	COG1923	regulation of RNA biosynthetic process
Ahae5227_10800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Ahae5227_10805	COG0802	atpase or kinase
Ahae5227_10835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ahae5227_10840	COG3300	MHYT domain
Ahae5227_10840	COG5001	Diguanylate cyclase
Ahae5227_10860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Ahae5227_10865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ahae5227_10870	COG1845	cytochrome c oxidase, subunit III
Ahae5227_10875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Ahae5227_10900	COG2249	NAD(P)H dehydrogenase (quinone) activity
Ahae5227_10905	COG1733	regulation of RNA biosynthetic process
Ahae5227_10910	COG0305	Participates in initiation and elongation during chromosome replication
Ahae5227_10915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Ahae5227_10930	COG1305	Transglutaminase-like
Ahae5227_10940	COG2308	Evidence 4 Homologs of previously reported genes of
Ahae5227_10955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Ahae5227_10970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Ahae5227_10980	COG0527	aspartate kinase activity
Ahae5227_10990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Ahae5227_11000	COG3038	cytochrome b561
Ahae5227_11005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Ahae5227_11010	COG2252	PERMEase
Ahae5227_11090	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Ahae5227_11095	COG0138	bifunctional purine biosynthesis protein purh
Ahae5227_11100	COG0151	Belongs to the GarS family
Ahae5227_11105	COG1464	Belongs to the NlpA lipoprotein family
Ahae5227_11110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Ahae5227_11115	COG2011	ABC-type metal ion transport system permease component
Ahae5227_11140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Ahae5227_11145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Ahae5227_11150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Ahae5227_11175	COG0052	Belongs to the universal ribosomal protein uS2 family
Ahae5227_11180	COG0024	Methionine aminopeptidase
Ahae5227_11190	COG2223	nitrite transmembrane transporter activity
Ahae5227_11210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ahae5227_11215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Ahae5227_11220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Ahae5227_11225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Ahae5227_11260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Ahae5227_11265	COG3161	chorismate lyase activity
Ahae5227_11270	COG0174	glutamine synthetase
Ahae5227_11275	COG0512	Glutamine amidotransferase of anthranilate synthase
Ahae5227_11290	COG3217	Mosc domain protein beta barrel domain protein
Ahae5227_11290	COG0633	Ferredoxin
Ahae5227_11315	COG0302	gtp cyclohydrolase
Ahae5227_11340	COG3739	integral membrane protein
Ahae5227_11355	COG2203	Gaf domain
Ahae5227_11355	COG3706	GGDEF domain
Ahae5227_11355	COG5001	Diguanylate cyclase
Ahae5227_11355	COG4251	negative regulation of phosphorylation
Ahae5227_11365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Ahae5227_11380	COG4172	Belongs to the ABC transporter superfamily
Ahae5227_11385	COG4239	(ABC) transporter, permease
Ahae5227_11390	COG4174	ABC transporter (Permease)
Ahae5227_11395	COG4166	transmembrane transport
Ahae5227_11400	COG0741	lytic transglycosylase activity
Ahae5227_11400	COG1388	LysM domain
Ahae5227_11400	COG0741	lytic transglycosylase activity
Ahae5227_11400	COG1388	LysM domain
Ahae5227_11405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Ahae5227_11415	COG2816	NAD+ diphosphatase activity
Ahae5227_11445	COG0583	DNA-binding transcription factor activity
Ahae5227_11450	COG1279	arginine transmembrane transporter activity
Ahae5227_11460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ahae5227_11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ahae5227_11470	COG0006	proline dipeptidase activity
Ahae5227_11500	COG2217	Heavy metal translocating P-type atpase
Ahae5227_11515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Ahae5227_11530	COG3384	dioxygenase
Ahae5227_11540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ahae5227_11590	COG3501	Rhs element vgr protein
Ahae5227_11595	COG2878	Part of a membrane complex involved in electron transport
Ahae5227_11600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Ahae5227_11630	COG0768	penicillin binding
Ahae5227_11635	COG0742	ribosomal rna small subunit methyltransferase
Ahae5227_11665	COG0616	signal peptide processing
Ahae5227_11670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Ahae5227_11680	COG0573	inorganic phosphate transmembrane transporter activity
Ahae5227_11695	COG0076	glutamate decarboxylase activity
Ahae5227_11700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Ahae5227_11710	COG1309	transcriptional regulator
Ahae5227_11740	COG0783	Belongs to the Dps family
Ahae5227_11750	COG0564	pseudouridine synthase activity
Ahae5227_11765	COG0352	thiamine-phosphate diphosphorylase activity
Ahae5227_11795	COG0612	Peptidase, M16
Ahae5227_11800	COG0384	phenazine biosynthesis protein PhzF
Ahae5227_11805	COG3293	Transposase
Ahae5227_11855	COG1686	Belongs to the peptidase S11 family
Ahae5227_11860	COG1252	NADH dehydrogenase
Ahae5227_11870	COG0415	Belongs to the DNA photolyase family
Ahae5227_11930	COG1271	oxidase subunit
Ahae5227_11935	COG1294	oxidase, subunit
Ahae5227_11955	COG0705	Rhomboid family
Ahae5227_11955	COG0457	Tetratricopeptide repeat
Ahae5227_11965	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Ahae5227_11970	COG4181	ATPase activity
Ahae5227_11980	COG0456	acetyltransferase
Ahae5227_12000	COG4771	TonB-dependent receptor
Ahae5227_12020	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Ahae5227_12040	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_12065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Ahae5227_12070	COG1597	lipid kinase activity
Ahae5227_12075	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Ahae5227_12105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Ahae5227_12120	COG2388	GCN5-related N-acetyl-transferase
Ahae5227_12165	COG4681	YaeQ
Ahae5227_12170	COG0523	cobalamin synthesis protein
Ahae5227_12180	COG1607	acyl-coa hydrolase
Ahae5227_12200	COG2814	Major facilitator Superfamily
Ahae5227_12205	COG1024	Enoyl-CoA hydratase
Ahae5227_12210	COG1012	belongs to the aldehyde dehydrogenase family
Ahae5227_12220	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_12240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ahae5227_12245	COG1414	Transcriptional regulator
Ahae5227_12250	COG0281	malic enzyme
Ahae5227_12255	COG0833	amino acid
Ahae5227_12270	COG1012	belongs to the aldehyde dehydrogenase family
Ahae5227_12280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ahae5227_12285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ahae5227_12295	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_12300	COG1454	alcohol dehydrogenase
Ahae5227_12305	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Ahae5227_12330	COG0625	glutathione transferase activity
Ahae5227_12350	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ahae5227_12350	COG1902	pentaerythritol trinitrate reductase activity
Ahae5227_12360	COG4689	acetoacetate decarboxylase
Ahae5227_12365	COG4221	oxidoreductase activity
Ahae5227_12390	COG2814	Major facilitator Superfamily
Ahae5227_12395	COG1566	PFAM secretion protein HlyD family protein
Ahae5227_12400	COG2050	protein possibly involved in aromatic compounds catabolism
Ahae5227_12410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ahae5227_12415	COG1090	epimerase
Ahae5227_12435	COG0420	3'-5' exonuclease activity
Ahae5227_12475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ahae5227_12480	COG2914	Belongs to the UPF0125 (RnfH) family
Ahae5227_12495	COG0121	glutamine amidotransferase
Ahae5227_12510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ahae5227_12515	COG0756	dUTP diphosphatase activity
Ahae5227_12520	COG0210	DNA helicase
Ahae5227_12525	COG2885	chlorophyll binding
Ahae5227_12530	COG0204	Acyl-transferase
Ahae5227_12540	COG0850	regulation of cytokinetic process
Ahae5227_12545	COG2894	cell division
Ahae5227_12550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Ahae5227_12560	COG1280	lysine exporter protein (LysE YggA)
Ahae5227_12565	COG1674	ftsk spoiiie
Ahae5227_12565	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Ahae5227_12570	COG0492	ferredoxin-NADP+ reductase activity
Ahae5227_12575	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Ahae5227_12585	COG0456	acetyltransferase
Ahae5227_12600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ahae5227_12610	COG0049	tRNA binding
Ahae5227_12645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Ahae5227_12645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ahae5227_12670	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Ahae5227_12680	COG0582	viral genome integration into host DNA
Ahae5227_12705	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ahae5227_12750	COG2132	Multicopper oxidase
Ahae5227_12765	COG2205	protein histidine kinase activity
Ahae5227_12770	COG2217	Heavy metal translocating P-type atpase
Ahae5227_12890	COG0564	pseudouridine synthase activity
Ahae5227_12900	COG0358	DNA primase activity
Ahae5227_12915	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Ahae5227_12930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Ahae5227_12965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Ahae5227_12975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Ahae5227_12975	COG0352	thiamine-phosphate diphosphorylase activity
Ahae5227_12975	COG0351	phosphomethylpyrimidine kinase
Ahae5227_12985	COG1652	LysM domain
Ahae5227_13010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Ahae5227_13015	COG1399	metal-binding, possibly nucleic acid-binding protein
Ahae5227_13020	COG3101	peptidyl-lysine hydroxylation
Ahae5227_13025	COG0009	L-threonylcarbamoyladenylate synthase
Ahae5227_13045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Ahae5227_13050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Ahae5227_13080	COG0747	negative chemotaxis
Ahae5227_13125	COG4106	trans-aconitate 2-methyltransferase activity
Ahae5227_13140	COG0596	Alpha beta hydrolase
Ahae5227_13140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ahae5227_13140	COG2226	methyltransferase
Ahae5227_13145	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ahae5227_13170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Ahae5227_13180	COG1196	nuclear chromosome segregation
Ahae5227_13190	COG0730	response to heat
Ahae5227_13210	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Ahae5227_13270	COG2358	TRAP transporter, solute receptor (TAXI family
Ahae5227_13290	COG0489	protein tyrosine kinase activity
Ahae5227_13310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ahae5227_13310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ahae5227_13320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Ahae5227_13340	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Ahae5227_13345	COG2081	HI0933 family
Ahae5227_13350	COG0668	transmembrane transport
Ahae5227_13370	COG0583	DNA-binding transcription factor activity
Ahae5227_13395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahae5227_13400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Ahae5227_13415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahae5227_13430	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Ahae5227_13440	COG0649	NAD binding
Ahae5227_13440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahae5227_13450	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahae5227_13465	COG2205	protein histidine kinase activity
Ahae5227_13470	COG0745	RESPONSE REGULATOR receiver
Ahae5227_13485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ahae5227_13490	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_13505	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_13525	COG0732	type I restriction modification DNA specificity domain
Ahae5227_13580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Ahae5227_13585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Ahae5227_13590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Ahae5227_13595	COG2076	Multidrug Resistance protein
Ahae5227_13615	COG2132	Multicopper oxidase
Ahae5227_13625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Ahae5227_13650	COG1968	undecaprenyl-diphosphatase activity
Ahae5227_13655	COG1214	PFAM Peptidase M22, glycoprotease
Ahae5227_13665	COG0494	nUDIX hydrolase
Ahae5227_13735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ahae5227_13745	COG1595	DNA-templated transcription, initiation
Ahae5227_13750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Ahae5227_13755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Ahae5227_13820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ahae5227_13830	COG1764	response to oxidative stress
Ahae5227_13855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ahae5227_13855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ahae5227_13870	COG0037	tRNA processing
Ahae5227_13880	COG0248	Ppx GppA phosphatase
Ahae5227_13905	COG0072	phenylalanine-tRNA ligase activity
Ahae5227_13940	COG1238	metal cluster binding
Ahae5227_13955	COG0625	glutathione transferase activity
Ahae5227_13975	COG0318	PFAM AMP-dependent synthetase and ligase
Ahae5227_13980	COG3028	Belongs to the UPF0307 family
Ahae5227_14005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Ahae5227_14010	COG0617	tRNA 3'-terminal CCA addition
Ahae5227_14015	COG1555	photosystem II stabilization
Ahae5227_14020	COG3956	TIGRFAM MazG family protein
Ahae5227_14050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Ahae5227_14070	COG5002	protein histidine kinase activity
Ahae5227_14070	COG2205	protein histidine kinase activity
Ahae5227_14070	COG0784	Response regulator, receiver
Ahae5227_14075	COG1024	Enoyl-CoA hydratase
Ahae5227_14080	COG2084	Dehydrogenase
Ahae5227_14085	COG3622	Belongs to the hyi family
Ahae5227_14135	COG2814	Major facilitator Superfamily
Ahae5227_14140	COG5285	phytanoyl-CoA dioxygenase
Ahae5227_14145	COG1917	Cupin 2, conserved barrel domain protein
Ahae5227_14155	COG0456	acetyltransferase
Ahae5227_14165	COG0431	NADPH-dependent FMN reductase
Ahae5227_14170	COG0798	PFAM Bile acid sodium symporter
Ahae5227_14180	COG0640	Transcriptional regulator
Ahae5227_14210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Ahae5227_14225	COG0732	type I restriction modification DNA specificity domain
Ahae5227_14235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Ahae5227_14315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Ahae5227_14325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Ahae5227_14340	COG0084	hydrolase, TatD family'
Ahae5227_14355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Ahae5227_14370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Ahae5227_14390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Ahae5227_14395	COG0583	DNA-binding transcription factor activity
Ahae5227_14400	COG4221	oxidoreductase activity
Ahae5227_14565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Ahae5227_14570	COG0440	acetolactate synthase activity
Ahae5227_14575	COG0028	Belongs to the TPP enzyme family
Ahae5227_14595	COG1466	dna polymerase III delta subunit
Ahae5227_14600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_14605	COG1136	(ABC) transporter
Ahae5227_14605	COG0577	efflux transmembrane transporter activity
Ahae5227_14610	COG1538	Outer membrane efflux protein
Ahae5227_14635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Ahae5227_14640	COG1162	GTPase activity
Ahae5227_14650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Ahae5227_14685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Ahae5227_14695	COG3781	membrane
Ahae5227_14730	COG1666	GTP binding
Ahae5227_14755	COG1956	GAF domain-containing protein
Ahae5227_14760	COG1607	acyl-coa hydrolase
Ahae5227_14820	COG1183	phosphatidylcholine synthase activity
Ahae5227_14825	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Ahae5227_14855	COG0739	heme binding
Ahae5227_14855	COG1196	nuclear chromosome segregation
Ahae5227_14855	COG0741	lytic transglycosylase activity
Ahae5227_14865	COG1702	phosphate starvation-inducible protein PhoH
Ahae5227_14890	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_14960	COG0788	formyltetrahydrofolate deformylase activity
Ahae5227_14985	COG4651	solute:proton antiporter activity
Ahae5227_14985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Ahae5227_15005	COG0210	DNA helicase
Ahae5227_15030	COG1733	regulation of RNA biosynthetic process
Ahae5227_15040	COG2900	Belongs to the SlyX family
Ahae5227_15055	COG1560	Kdo2-lipid A biosynthetic process
Ahae5227_15115	COG0473	3-isopropylmalate dehydrogenase activity
Ahae5227_15150	COG0494	nUDIX hydrolase
Ahae5227_15185	COG0625	glutathione transferase activity
Ahae5227_15200	COG0564	pseudouridine synthase activity
Ahae5227_15210	COG1530	ribonuclease E activity
Ahae5227_15215	COG0318	PFAM AMP-dependent synthetase and ligase
Ahae5227_15230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ahae5227_15240	COG0534	Mate efflux family protein
Ahae5227_15245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Ahae5227_15270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Ahae5227_15295	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Ahae5227_15355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ahae5227_15370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Ahae5227_15380	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
Ahae5227_15380	COG0644	oxidoreductase
Ahae5227_15385	COG0425	Belongs to the sulfur carrier protein TusA family
Ahae5227_15390	COG4535	Mg2 and Co2 transporter CorC
Ahae5227_15395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Ahae5227_15415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Ahae5227_15425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Ahae5227_15440	COG0789	Transcriptional regulator
Ahae5227_15445	COG0598	Magnesium transport protein CorA
Ahae5227_15450	COG1185	polyribonucleotide nucleotidyltransferase activity
Ahae5227_15455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Ahae5227_15465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Ahae5227_15470	COG1074	ATP-dependent DNA helicase activity
Ahae5227_15475	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Ahae5227_15500	COG2226	methyltransferase
Ahae5227_15520	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_15535	COG1116	anion transmembrane transporter activity
Ahae5227_15540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ahae5227_15550	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Ahae5227_15565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Ahae5227_15565	COG2111	Na H antiporter
Ahae5227_15570	COG1006	Multisubunit Na H antiporter MnhC subunit
Ahae5227_15575	COG0651	ATP synthesis coupled electron transport
Ahae5227_15580	COG1863	multisubunit Na H antiporter MnhE subunit
Ahae5227_15585	COG2212	antiporter activity
Ahae5227_15600	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_15605	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_15625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Ahae5227_15635	COG0195	Participates in both transcription termination and antitermination
Ahae5227_15685	COG0237	dephospho-CoA kinase activity
Ahae5227_15700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Ahae5227_15710	COG0497	DNA recombination
Ahae5227_15720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Ahae5227_15745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Ahae5227_15805	COG1132	(ABC) transporter
Ahae5227_15815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Ahae5227_15830	COG0326	Molecular chaperone. Has ATPase activity
Ahae5227_15840	COG2056	Na+-H+ antiporter family
Ahae5227_15890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Ahae5227_15900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Ahae5227_15910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ahae5227_15940	COG0546	phosphoglycolate phosphatase activity
Ahae5227_15990	COG0181	hydroxymethylbilane synthase activity
Ahae5227_16000	COG3275	phosphorelay sensor kinase activity
Ahae5227_16025	COG0494	nUDIX hydrolase
Ahae5227_16035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Ahae5227_16040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ahae5227_16050	COG0772	Belongs to the SEDS family
Ahae5227_16075	COG4974	Belongs to the 'phage' integrase family
Ahae5227_16080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ahae5227_16090	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Ahae5227_16095	COG1686	Belongs to the peptidase S11 family
Ahae5227_16100	COG2197	response regulator
Ahae5227_16115	COG0793	Belongs to the peptidase S41A family
Ahae5227_16120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Ahae5227_16125	COG0795	lipopolysaccharide-transporting ATPase activity
Ahae5227_16130	COG0795	lipopolysaccharide-transporting ATPase activity
Ahae5227_16165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ahae5227_16165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ahae5227_16170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Ahae5227_16175	COG0004	ammonium transporteR
Ahae5227_16180	COG0347	Belongs to the P(II) protein family
Ahae5227_16270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ahae5227_16275	COG1230	cation diffusion facilitator family transporter
Ahae5227_16285	COG0640	Transcriptional regulator
Ahae5227_16290	COG2217	Heavy metal translocating P-type atpase
Ahae5227_16295	COG0789	Transcriptional regulator
Ahae5227_16335	COG2814	Major facilitator Superfamily
Ahae5227_16375	COG0633	Ferredoxin
Ahae5227_16420	COG0606	chelatase, subunit chli
Ahae5227_16455	COG0318	PFAM AMP-dependent synthetase and ligase
Ahae5227_16470	COG2860	membrane
Ahae5227_16480	COG1253	flavin adenine dinucleotide binding
Ahae5227_16500	COG2814	Major facilitator Superfamily
Ahae5227_16510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Ahae5227_16535	COG2814	Major facilitator Superfamily
Ahae5227_16545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Ahae5227_16550	COG1283	sodium-dependent phosphate transmembrane transporter activity
Ahae5227_16580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Ahae5227_16595	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Ahae5227_16600	COG3162	membrane
Ahae5227_16605	COG2205	protein histidine kinase activity
Ahae5227_16630	COG1652	LysM domain
Ahae5227_16635	COG0758	DNA mediated transformation
Ahae5227_16650	COG1309	transcriptional regulator
Ahae5227_16655	COG2814	Major facilitator Superfamily
Ahae5227_16665	COG0386	Belongs to the glutathione peroxidase family
Ahae5227_16690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Ahae5227_16700	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Ahae5227_16740	COG1121	(ABC) transporter
Ahae5227_16745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ahae5227_16750	COG1280	lysine exporter protein (LysE YggA)
Ahae5227_16755	COG2837	iron assimilation
Ahae5227_16790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Ahae5227_16820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ahae5227_16820	COG0519	Catalyzes the synthesis of GMP from XMP
Ahae5227_16825	COG4399	Belongs to the UPF0754 family
Ahae5227_16835	COG2259	Doxx family
Ahae5227_16840	COG0586	Pfam SNARE associated Golgi protein
Ahae5227_16855	COG1192	Involved in chromosome partitioning
Ahae5227_16865	COG0271	Belongs to the BolA IbaG family
Ahae5227_16900	COG3756	Protein conserved in bacteria
Ahae5227_16955	COG3293	Transposase
Ahae5227_17030	COG2015	COG2015, Alkyl sulfatase and related hydrolases
Ahae5227_17070	COG0735	belongs to the Fur family
Ahae5227_17125	COG2801	Transposase and inactivated derivatives
Ahae5227_17140	COG0477	Major facilitator Superfamily
Ahae5227_17145	COG1024	Enoyl-CoA hydratase
Ahae5227_17150	COG1024	Enoyl-CoA hydratase
Ahae5227_17155	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_17160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ahae5227_17195	COG0251	oxidation-reduction process
Ahae5227_17225	COG0456	acetyltransferase
Ahae5227_17235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Ahae5227_17250	COG3293	Transposase
Ahae5227_17265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Ahae5227_17285	COG1802	Transcriptional regulator
Ahae5227_17295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ahae5227_17305	COG2826	transposase and inactivated derivatives, IS30 family
Ahae5227_17310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Ahae5227_17325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Ahae5227_17335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Ahae5227_17345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Ahae5227_17360	COG1063	alcohol dehydrogenase
Ahae5227_17390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Ahae5227_17395	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Ahae5227_17430	COG3023	N-Acetylmuramoyl-L-alanine amidase
Ahae5227_17480	COG0546	phosphoglycolate phosphatase activity
Ahae5227_17485	COG1028	Short-chain dehydrogenase reductase Sdr
Ahae5227_17495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Ahae5227_17495	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Ahae5227_17500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ahae5227_17505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ahae5227_17510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ahae5227_17515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ahae5227_17520	COG1116	anion transmembrane transporter activity
Ahae5227_17525	COG1309	transcriptional regulator
Ahae5227_17535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Ahae5227_17545	COG0196	riboflavin kinase activity
Ahae5227_17550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Ahae5227_17560	COG1047	Peptidyl-prolyl cis-trans
Ahae5227_17600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Ahae5227_17625	COG0583	DNA-binding transcription factor activity
Ahae5227_17635	COG0443	Heat shock 70 kDa protein
Ahae5227_17645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Ahae5227_17660	COG3293	Transposase
Ahae5227_17680	COG2951	lytic endotransglycosylase activity
Ahae5227_17685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Ahae5227_17710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Ahae5227_17730	COG1960	acyl-CoA dehydrogenase activity
Ahae5227_17740	COG0861	Integral membrane protein TerC family
Ahae5227_17755	COG0402	S-adenosylhomocysteine deaminase activity
Ahae5227_17770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ahae5227_17780	COG0706	membrane insertase activity
Ahae5227_17810	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP