locus-tag	class	description
AhaeAN3_00010	COG0592	DNA-directed DNA polymerase activity
AhaeAN3_00020	COG0187	DNA topoisomerase II activity
AhaeAN3_00025	COG0586	Pfam SNARE associated Golgi protein
AhaeAN3_00030	COG0488	(ABC) transporter
AhaeAN3_00060	COG0596	Alpha beta hydrolase
AhaeAN3_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AhaeAN3_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AhaeAN3_00110	COG0471	metal ion transport
AhaeAN3_00110	COG3273	potassium ion transport
AhaeAN3_00120	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN3_00125	COG3738	Protein conserved in bacteria
AhaeAN3_00135	COG0733	neurotransmitter:sodium symporter activity
AhaeAN3_00175	COG2233	PERMEase
AhaeAN3_00190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_00205	COG0484	heat shock protein binding
AhaeAN3_00220	COG2814	Major facilitator Superfamily
AhaeAN3_00225	COG0656	L-ascorbic acid biosynthetic process
AhaeAN3_00230	COG0583	DNA-binding transcription factor activity
AhaeAN3_00245	COG1064	alcohol dehydrogenase
AhaeAN3_00250	COG2818	Glycosylase
AhaeAN3_00265	COG1194	a g-specific adenine glycosylase
AhaeAN3_00275	COG5487	UPF0391 membrane protein
AhaeAN3_00280	COG2983	Belongs to the UPF0260 family
AhaeAN3_00285	COG2133	pyrroloquinoline quinone binding
AhaeAN3_00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AhaeAN3_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AhaeAN3_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AhaeAN3_00320	COG1335	isochorismatase
AhaeAN3_00325	COG1522	sequence-specific DNA binding
AhaeAN3_00340	COG3328	transposase activity
AhaeAN3_00350	COG1230	cation diffusion facilitator family transporter
AhaeAN3_00370	COG2217	Heavy metal translocating P-type atpase
AhaeAN3_00375	COG2205	protein histidine kinase activity
AhaeAN3_00390	COG2132	Multicopper oxidase
AhaeAN3_00420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AhaeAN3_00430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AhaeAN3_00435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AhaeAN3_00440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AhaeAN3_00460	COG3830	Belongs to the UPF0237 family
AhaeAN3_00460	COG0560	Phosphoserine phosphatase
AhaeAN3_00520	COG0583	DNA-binding transcription factor activity
AhaeAN3_00550	COG0534	Mate efflux family protein
AhaeAN3_00555	COG0436	Aminotransferase
AhaeAN3_00565	COG2733	membrane
AhaeAN3_00580	COG2918	glutathione biosynthetic process
AhaeAN3_00595	COG3150	esterase
AhaeAN3_00635	COG1247	-acetyltransferase
AhaeAN3_00665	COG0625	glutathione transferase activity
AhaeAN3_00685	COG1393	Belongs to the ArsC family
AhaeAN3_00690	COG0708	Exodeoxyribonuclease III
AhaeAN3_00715	COG0300	oxidoreductase activity
AhaeAN3_00760	COG0386	Belongs to the glutathione peroxidase family
AhaeAN3_00765	COG0189	ligase activity
AhaeAN3_00785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AhaeAN3_00795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AhaeAN3_00835	COG2119	membrane
AhaeAN3_00840	COG4774	siderophore transport
AhaeAN3_00845	COG0426	domain, Protein
AhaeAN3_00845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN3_00870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AhaeAN3_00895	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN3_00900	COG1519	Transferase
AhaeAN3_00905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AhaeAN3_00910	COG0668	transmembrane transport
AhaeAN3_00915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN3_00945	COG3706	GGDEF domain
AhaeAN3_00970	COG0351	phosphomethylpyrimidine kinase
AhaeAN3_00970	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN3_00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN3_00980	COG2814	Major facilitator Superfamily
AhaeAN3_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN3_01015	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN3_01025	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AhaeAN3_01055	COG3158	transport of potassium into the cell
AhaeAN3_01095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AhaeAN3_01125	COG0659	secondary active sulfate transmembrane transporter activity
AhaeAN3_01140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AhaeAN3_01175	COG0427	acetyl-CoA hydrolase
AhaeAN3_01180	COG2205	protein histidine kinase activity
AhaeAN3_01185	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_01215	COG0583	DNA-binding transcription factor activity
AhaeAN3_01225	COG0789	Transcriptional regulator
AhaeAN3_01230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AhaeAN3_01230	COG3320	Male sterility
AhaeAN3_01235	COG4221	oxidoreductase activity
AhaeAN3_01240	COG2873	o-acetylhomoserine
AhaeAN3_01245	COG0488	(ABC) transporter
AhaeAN3_01315	COG0833	amino acid
AhaeAN3_01355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AhaeAN3_01360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AhaeAN3_01365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AhaeAN3_01370	COG2226	methyltransferase
AhaeAN3_01420	COG0070	glutamate synthase
AhaeAN3_01420	COG0069	glutamate synthase activity
AhaeAN3_01420	COG0067	glutamate synthase
AhaeAN3_01425	COG0493	'glutamate synthase
AhaeAN3_01445	COG1704	LemA family
AhaeAN3_01450	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AhaeAN3_01465	COG1487	ribonuclease activity
AhaeAN3_01475	COG4969	Belongs to the N-Me-Phe pilin family
AhaeAN3_01495	COG4636	protein conserved in cyanobacteria
AhaeAN3_01500	COG3307	-O-antigen
AhaeAN3_01520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN3_01530	COG0194	GDP metabolic process
AhaeAN3_01535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AhaeAN3_01540	COG4969	Belongs to the N-Me-Phe pilin family
AhaeAN3_01610	COG0228	four-way junction DNA binding
AhaeAN3_01615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AhaeAN3_01625	COG0335	large ribosomal subunit rRNA binding
AhaeAN3_01635	COG5380	lipid catabolic process
AhaeAN3_01640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AhaeAN3_01665	COG1196	nuclear chromosome segregation
AhaeAN3_01665	COG0739	heme binding
AhaeAN3_01665	COG0741	lytic transglycosylase activity
AhaeAN3_01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AhaeAN3_01675	COG0277	FAD linked oxidase domain protein
AhaeAN3_01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AhaeAN3_01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN3_01710	COG1289	transmembrane transporter activity
AhaeAN3_01715	COG0628	permease
AhaeAN3_01720	COG1192	Involved in chromosome partitioning
AhaeAN3_01730	COG2226	methyltransferase
AhaeAN3_01775	COG2072	flavoprotein involved in K transport
AhaeAN3_01825	COG0471	metal ion transport
AhaeAN3_01835	COG1983	PspC domain protein
AhaeAN3_01845	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_01900	COG1127	ABC transporter
AhaeAN3_01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AhaeAN3_01910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AhaeAN3_01915	COG2854	intermembrane phospholipid transfer
AhaeAN3_01930	COG0598	Magnesium transport protein CorA
AhaeAN3_01945	COG1040	competence protein
AhaeAN3_01950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AhaeAN3_01965	COG2937	Belongs to the GPAT DAPAT family
AhaeAN3_01970	COG1946	Acyl-CoA thioesterase
AhaeAN3_01975	COG1301	dicarboxylic acid transport
AhaeAN3_01995	COG1959	2 iron, 2 sulfur cluster binding
AhaeAN3_02005	COG0433	COG0433 Predicted ATPase
AhaeAN3_02025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AhaeAN3_02045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AhaeAN3_02095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AhaeAN3_02175	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AhaeAN3_02205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AhaeAN3_02235	COG0339	signal peptide processing
AhaeAN3_02240	COG0557	exoribonuclease II activity
AhaeAN3_02285	COG0179	Fumarylacetoacetate (FAA) hydrolase
AhaeAN3_02290	COG2207	Transcriptional regulator
AhaeAN3_02300	COG1295	ribonuclease BN
AhaeAN3_02340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AhaeAN3_02375	COG2813	Specifically methylates the guanine in position
AhaeAN3_02375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AhaeAN3_02385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AhaeAN3_02395	COG3128	pkhd-type hydroxylase
AhaeAN3_02405	COG4771	TonB-dependent receptor
AhaeAN3_02415	COG0740	serine-type endopeptidase activity
AhaeAN3_02435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN3_02435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN3_02440	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN3_02440	COG2207	Transcriptional regulator
AhaeAN3_02445	COG0697	spore germination
AhaeAN3_02455	COG0857	belongs to the CobB CobQ family
AhaeAN3_02455	COG0280	phosphate acetyltransferase
AhaeAN3_02460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AhaeAN3_02470	COG2267	carboxylic ester hydrolase activity
AhaeAN3_02485	COG0793	Belongs to the peptidase S41A family
AhaeAN3_02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AhaeAN3_02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN3_02520	COG1408	metallophosphoesterase
AhaeAN3_02530	COG2199	diguanylate cyclase activity
AhaeAN3_02570	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_02585	COG1309	transcriptional regulator
AhaeAN3_02600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN3_02605	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_02660	COG2969	positive regulation of protein catabolic process
AhaeAN3_02665	COG0625	glutathione transferase activity
AhaeAN3_02670	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AhaeAN3_02675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AhaeAN3_02685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AhaeAN3_02690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AhaeAN3_02695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AhaeAN3_02710	COG2975	iron-sulfur cluster assembly
AhaeAN3_02730	COG1426	Protein conserved in bacteria
AhaeAN3_02765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AhaeAN3_02775	COG1862	Preprotein translocase
AhaeAN3_02805	COG5002	protein histidine kinase activity
AhaeAN3_02810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AhaeAN3_02820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AhaeAN3_02880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AhaeAN3_02920	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_02925	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_02935	COG2205	protein histidine kinase activity
AhaeAN3_02940	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_02975	COG2096	Adenosyltransferase
AhaeAN3_02980	COG4206	TonB-dependent receptor
AhaeAN3_03005	COG3501	Rhs element vgr protein
AhaeAN3_03055	COG0285	dihydrofolate synthase activity
AhaeAN3_03070	COG0450	alkyl hydroperoxide reductase
AhaeAN3_03090	COG0477	Major facilitator Superfamily
AhaeAN3_03095	COG1272	protein, Hemolysin III
AhaeAN3_03130	COG0183	Belongs to the thiolase family
AhaeAN3_03140	COG2207	Transcriptional regulator
AhaeAN3_03145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AhaeAN3_03160	COG3501	Rhs element vgr protein
AhaeAN3_03170	COG0739	heme binding
AhaeAN3_03175	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_03200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN3_03215	COG0183	Belongs to the thiolase family
AhaeAN3_03225	COG2885	chlorophyll binding
AhaeAN3_03225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN3_03235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN3_03235	COG2885	chlorophyll binding
AhaeAN3_03240	COG1690	Belongs to the RtcB family
AhaeAN3_03245	COG0833	amino acid
AhaeAN3_03255	COG2233	PERMEase
AhaeAN3_03265	COG1970	mechanosensitive ion channel activity
AhaeAN3_03285	COG4772	TonB-dependent receptor
AhaeAN3_03295	COG0354	folic acid binding
AhaeAN3_03305	COG2824	Alkylphosphonate utilization operon protein PhnA
AhaeAN3_03310	COG3422	double-strand break repair
AhaeAN3_03340	COG0840	transmembrane signaling receptor activity
AhaeAN3_03345	COG2198	Histidine kinase
AhaeAN3_03345	COG2198	Histidine kinase
AhaeAN3_03345	COG0643	Histidine kinase
AhaeAN3_03345	COG0643	Histidine kinase
AhaeAN3_03360	COG5510	response to toxic substance
AhaeAN3_03370	COG2832	Protein of unknown function (DUF454)
AhaeAN3_03375	COG1376	ErfK ybiS ycfS ynhG family protein
AhaeAN3_03420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AhaeAN3_03430	COG1289	transmembrane transporter activity
AhaeAN3_03435	COG2814	Major facilitator Superfamily
AhaeAN3_03450	COG0786	glutamate:sodium symporter activity
AhaeAN3_03455	COG1115	amino acid carrier protein
AhaeAN3_03460	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN3_03465	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AhaeAN3_03515	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN3_03525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN3_03530	COG1077	Cell shape determining protein MreB Mrl
AhaeAN3_03535	COG1792	Involved in formation and maintenance of cell shape
AhaeAN3_03545	COG0424	maF-like protein
AhaeAN3_03550	COG1530	ribonuclease E activity
AhaeAN3_03560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN3_03570	COG0560	Phosphoserine phosphatase
AhaeAN3_03590	COG2851	Citrate transporter
AhaeAN3_03595	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN3_03620	COG1113	amino acid transport
AhaeAN3_03625	COG2828	Protein conserved in bacteria
AhaeAN3_03630	COG0142	geranyltranstransferase activity
AhaeAN3_03645	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN3_03665	COG2194	sulfuric ester hydrolase activity
AhaeAN3_03670	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_03675	COG0642	Histidine kinase
AhaeAN3_03685	COG1126	abc transporter atp-binding protein
AhaeAN3_03690	COG0765	amino acid transport
AhaeAN3_03695	COG0765	amino acid transport
AhaeAN3_03705	COG0004	ammonium transporteR
AhaeAN3_03730	COG0525	valine-tRNA ligase activity
AhaeAN3_03770	COG0393	Putative heavy-metal-binding
AhaeAN3_03775	COG1538	Outer membrane efflux protein
AhaeAN3_03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_03790	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN3_03820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AhaeAN3_03835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AhaeAN3_03835	COG1648	precorrin-2 dehydrogenase activity
AhaeAN3_03840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AhaeAN3_03850	COG1733	regulation of RNA biosynthetic process
AhaeAN3_03860	COG0531	amino acid
AhaeAN3_03875	COG0321	lipoyl(octanoyl) transferase activity
AhaeAN3_03905	COG1280	lysine exporter protein (LysE YggA)
AhaeAN3_03910	COG0583	DNA-binding transcription factor activity
AhaeAN3_03915	COG0500	methyltransferase
AhaeAN3_03920	COG0586	Pfam SNARE associated Golgi protein
AhaeAN3_03940	COG2009	succinate dehydrogenase
AhaeAN3_03945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AhaeAN3_03950	COG1053	succinate dehydrogenase
AhaeAN3_03955	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AhaeAN3_03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN3_03990	COG2268	Band 7 protein
AhaeAN3_03995	COG1585	Membrane protein implicated in regulation of membrane protease activity
AhaeAN3_04005	COG2354	Protein conserved in bacteria
AhaeAN3_04010	COG2321	neutral zinc metallopeptidase
AhaeAN3_04030	COG0110	maltose O-acetyltransferase activity
AhaeAN3_04050	COG0505	Belongs to the CarA family
AhaeAN3_04075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN3_04090	COG2304	oxidoreductase activity
AhaeAN3_04115	COG0584	glycerophosphoryl diester phosphodiesterase
AhaeAN3_04120	COG2194	sulfuric ester hydrolase activity
AhaeAN3_04125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN3_04130	COG2239	Acts as a magnesium transporter
AhaeAN3_04140	COG0501	Belongs to the peptidase M48B family
AhaeAN3_04145	COG1196	nuclear chromosome segregation
AhaeAN3_04145	COG0739	heme binding
AhaeAN3_04145	COG0741	lytic transglycosylase activity
AhaeAN3_04160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AhaeAN3_04165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AhaeAN3_04195	COG0725	ABC transporter, periplasmic molybdate-binding protein
AhaeAN3_04200	COG4149	molybdate abc transporter
AhaeAN3_04220	COG4521	taurine ABC transporter
AhaeAN3_04225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AhaeAN3_04230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN3_04235	COG2175	clavaminate synthase activity
AhaeAN3_04265	COG0589	response to stress
AhaeAN3_04280	COG0242	peptide deformylase activity
AhaeAN3_04285	COG2852	Protein conserved in bacteria
AhaeAN3_04305	COG0306	phosphate transporter
AhaeAN3_04330	COG1115	amino acid carrier protein
AhaeAN3_04340	COG0019	diaminopimelate decarboxylase activity
AhaeAN3_04345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AhaeAN3_04355	COG1280	lysine exporter protein (LysE YggA)
AhaeAN3_04360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AhaeAN3_04400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_04425	COG1671	Belongs to the UPF0178 family
AhaeAN3_04440	COG4591	ABC-type transport system involved in lipoprotein release permease component
AhaeAN3_04445	COG1136	(ABC) transporter
AhaeAN3_04450	COG2333	competence protein COMEC
AhaeAN3_04450	COG0658	competence protein
AhaeAN3_04460	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AhaeAN3_04460	COG0616	signal peptide processing
AhaeAN3_04470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AhaeAN3_04480	COG0628	permease
AhaeAN3_04520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN3_04540	COG0823	Involved in the tonB-independent uptake of proteins
AhaeAN3_04560	COG0824	Thioesterase
AhaeAN3_04570	COG2255	four-way junction helicase activity
AhaeAN3_04585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AhaeAN3_04585	COG0047	phosphoribosylformylglycinamidine synthase activity
AhaeAN3_04605	COG3323	Protein of unknown function (DUF1653)
AhaeAN3_04605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN3_04610	COG0778	Nitroreductase
AhaeAN3_04615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN3_04615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN3_04615	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AhaeAN3_04620	COG1105	Belongs to the carbohydrate kinase PfkB family
AhaeAN3_04625	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AhaeAN3_04625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AhaeAN3_04630	COG1024	Enoyl-CoA hydratase
AhaeAN3_04635	COG1051	belongs to the nudix hydrolase family
AhaeAN3_04635	COG1056	cytidyltransferase-related domain
AhaeAN3_04640	COG0583	DNA-binding transcription factor activity
AhaeAN3_04645	COG1942	4-Oxalocrotonate Tautomerase
AhaeAN3_04665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN3_04680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AhaeAN3_04685	COG0602	queuosine metabolic process
AhaeAN3_04700	COG0583	DNA-binding transcription factor activity
AhaeAN3_04705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AhaeAN3_04710	COG4208	sulfate ABC transporter
AhaeAN3_04715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AhaeAN3_04725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AhaeAN3_04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AhaeAN3_04735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AhaeAN3_04785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN3_04795	COG0481	GTPase activity
AhaeAN3_04810	COG0571	ribonuclease III activity
AhaeAN3_04815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AhaeAN3_04830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AhaeAN3_04855	COG0436	Aminotransferase
AhaeAN3_04875	COG0556	nucleotide-excision repair
AhaeAN3_04920	COG1840	ABC-type Fe3 transport system, periplasmic component
AhaeAN3_04925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AhaeAN3_04945	COG0583	DNA-binding transcription factor activity
AhaeAN3_04950	COG0596	Alpha beta hydrolase
AhaeAN3_04955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN3_04960	COG1773	rubredoxin
AhaeAN3_04970	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AhaeAN3_04980	COG0175	sulfate reduction
AhaeAN3_04995	COG0222	ribosome binding
AhaeAN3_05000	COG1253	flavin adenine dinucleotide binding
AhaeAN3_05015	COG3015	lipoprotein NlpE involved in copper resistance
AhaeAN3_05030	COG0517	IMP dehydrogenase activity
AhaeAN3_05030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN3_05035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AhaeAN3_05045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AhaeAN3_05050	COG1137	ATPase activity
AhaeAN3_05060	COG3676	manually curated
AhaeAN3_05095	COG4122	O-methyltransferase activity
AhaeAN3_05105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AhaeAN3_05140	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AhaeAN3_05170	COG4783	chaperone-mediated protein folding
AhaeAN3_05190	COG1610	YqeY-like protein
AhaeAN3_05255	COG1414	Transcriptional regulator
AhaeAN3_05275	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN3_05285	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN3_05290	COG2271	Major facilitator Superfamily
AhaeAN3_05305	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN3_05315	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN3_05320	COG0028	Belongs to the TPP enzyme family
AhaeAN3_05340	COG0482	sulfurtransferase activity
AhaeAN3_05355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AhaeAN3_05360	COG1686	Belongs to the peptidase S11 family
AhaeAN3_05380	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AhaeAN3_05390	COG0583	DNA-binding transcription factor activity
AhaeAN3_05395	COG1067	ATP-dependent peptidase activity
AhaeAN3_05415	COG0254	rRNA binding
AhaeAN3_05435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AhaeAN3_05440	COG1966	Carbon starvation protein
AhaeAN3_05445	COG2879	small protein
AhaeAN3_05450	COG0714	Associated with various cellular activities
AhaeAN3_05480	COG1741	Belongs to the pirin family
AhaeAN3_05495	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN3_05495	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN3_05505	COG0582	viral genome integration into host DNA
AhaeAN3_05590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN3_05595	COG0569	domain protein
AhaeAN3_05600	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AhaeAN3_05605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AhaeAN3_05610	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AhaeAN3_05615	COG2205	protein histidine kinase activity
AhaeAN3_05620	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_05625	COG0174	glutamine synthetase
AhaeAN3_05710	COG0582	viral genome integration into host DNA
AhaeAN3_05735	COG2995	paraquat-inducible protein a
AhaeAN3_05740	COG3008	intermembrane lipid transfer
AhaeAN3_05740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AhaeAN3_05780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AhaeAN3_05790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN3_05795	COG1469	GTP cyclohydrolase I activity
AhaeAN3_05810	COG0523	cobalamin synthesis protein
AhaeAN3_05815	COG1414	Transcriptional regulator
AhaeAN3_05820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AhaeAN3_05825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AhaeAN3_05830	COG0183	Belongs to the thiolase family
AhaeAN3_05835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AhaeAN3_05840	COG0596	Alpha beta hydrolase
AhaeAN3_05845	COG2271	Major facilitator Superfamily
AhaeAN3_05850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AhaeAN3_05855	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN3_05860	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN3_05865	COG0710	3-dehydroquinate dehydratase activity
AhaeAN3_05870	COG3420	alginic acid biosynthetic process
AhaeAN3_05875	COG3659	wide pore channel activity
AhaeAN3_05880	COG4993	Dehydrogenase
AhaeAN3_05890	COG2351	hydroxyisourate hydrolase activity
AhaeAN3_05895	COG2233	PERMEase
AhaeAN3_05915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN3_05925	COG4266	Belongs to the allantoicase family
AhaeAN3_05940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN3_05950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN3_05965	COG0583	DNA-binding transcription factor activity
AhaeAN3_05975	COG2188	Transcriptional regulator
AhaeAN3_05995	COG0010	Belongs to the arginase family
AhaeAN3_06000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN3_06005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN3_06040	COG0243	molybdopterin cofactor binding
AhaeAN3_06045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AhaeAN3_06050	COG2837	iron assimilation
AhaeAN3_06080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN3_06090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN3_06125	COG1309	transcriptional regulator
AhaeAN3_06145	COG2072	flavoprotein involved in K transport
AhaeAN3_06150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AhaeAN3_06155	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN3_06160	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN3_06165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN3_06170	COG4770	biotin carboxylase activity
AhaeAN3_06175	COG0501	Belongs to the peptidase M48B family
AhaeAN3_06185	COG1765	OsmC-like protein
AhaeAN3_06235	COG4133	protoheme IX ABC transporter activity
AhaeAN3_06265	COG0308	aminopeptidase N
AhaeAN3_06270	COG1760	l-serine dehydratase
AhaeAN3_06280	COG1714	RDD family
AhaeAN3_06290	COG0475	glutathione-regulated potassium exporter activity
AhaeAN3_06290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN3_06295	COG3135	benzoate transporter
AhaeAN3_06305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AhaeAN3_06325	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AhaeAN3_06360	COG0316	Belongs to the HesB IscA family
AhaeAN3_06365	COG0822	iron-sulfur transferase activity
AhaeAN3_06390	COG0776	regulation of translation
AhaeAN3_06395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN3_06410	COG2137	regulation of response to DNA damage stimulus
AhaeAN3_06420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AhaeAN3_06425	COG1011	Hydrolase
AhaeAN3_06430	COG1218	3'(2'),5'-bisphosphate nucleotidase
AhaeAN3_06450	COG0268	Binds directly to 16S ribosomal RNA
AhaeAN3_06455	COG0702	epimerase
AhaeAN3_06460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AhaeAN3_06475	COG0183	Belongs to the thiolase family
AhaeAN3_06520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AhaeAN3_06525	COG0583	DNA-binding transcription factor activity
AhaeAN3_06530	COG0424	maF-like protein
AhaeAN3_06630	COG3634	alkyl hydroperoxide reductase activity
AhaeAN3_06645	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AhaeAN3_06650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AhaeAN3_06665	COG2353	YceI-like domain
AhaeAN3_06670	COG3153	acetyltransferase
AhaeAN3_06685	COG3698	Phosphodiester glycosidase
AhaeAN3_06695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AhaeAN3_06705	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN3_06705	COG0506	proline dehydrogenase activity
AhaeAN3_06705	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN3_06720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN3_06740	COG1132	(ABC) transporter
AhaeAN3_06750	COG0668	transmembrane transport
AhaeAN3_06755	COG3122	Protein conserved in bacteria
AhaeAN3_06775	COG0640	Transcriptional regulator
AhaeAN3_06800	COG2850	peptidyl-arginine hydroxylation
AhaeAN3_06815	COG1454	alcohol dehydrogenase
AhaeAN3_06820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AhaeAN3_06840	COG0069	glutamate synthase activity
AhaeAN3_06850	COG2814	Major facilitator Superfamily
AhaeAN3_06865	COG0439	Biotin carboxylase
AhaeAN3_06870	COG0511	ligase activity, forming carbon-carbon bonds
AhaeAN3_06880	COG1116	anion transmembrane transporter activity
AhaeAN3_06880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN3_06890	COG2223	nitrite transmembrane transporter activity
AhaeAN3_06895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN3_06895	COG2146	nitrite reductase [NAD(P)H] activity
AhaeAN3_06900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN3_06905	COG0243	molybdopterin cofactor binding
AhaeAN3_06920	COG0243	molybdopterin cofactor binding
AhaeAN3_06925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AhaeAN3_06940	COG0315	cyclic pyranopterin monophosphate synthase activity
AhaeAN3_06940	COG0521	Mo-molybdopterin cofactor biosynthetic process
AhaeAN3_06945	COG0303	'Molybdopterin
AhaeAN3_06955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN3_06960	COG0697	spore germination
AhaeAN3_06980	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AhaeAN3_06985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AhaeAN3_07025	COG1309	transcriptional regulator
AhaeAN3_07035	COG3852	Histidine kinase
AhaeAN3_07045	COG0528	UMP kinase activity
AhaeAN3_07055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AhaeAN3_07060	COG0575	Belongs to the CDS family
AhaeAN3_07095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN3_07100	COG2207	Transcriptional regulator
AhaeAN3_07105	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN3_07110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN3_07115	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_07120	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_07165	COG2814	Major facilitator Superfamily
AhaeAN3_07180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AhaeAN3_07195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AhaeAN3_07200	COG0406	alpha-ribazole phosphatase activity
AhaeAN3_07220	COG4771	TonB-dependent receptor
AhaeAN3_07230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN3_07235	COG0730	response to heat
AhaeAN3_07255	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN3_07280	COG0537	adenosine 5'-monophosphoramidase activity
AhaeAN3_07310	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AhaeAN3_07345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AhaeAN3_07365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN3_07385	COG2205	protein histidine kinase activity
AhaeAN3_07405	COG3706	GGDEF domain
AhaeAN3_07415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN3_07425	COG2801	Transposase and inactivated derivatives
AhaeAN3_07460	COG4774	siderophore transport
AhaeAN3_07470	COG0583	DNA-binding transcription factor activity
AhaeAN3_07485	COG0183	Belongs to the thiolase family
AhaeAN3_07490	COG2814	Major facilitator Superfamily
AhaeAN3_07505	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_07515	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN3_07520	COG1309	transcriptional regulator
AhaeAN3_07525	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_07530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN3_07535	COG1024	Enoyl-CoA hydratase
AhaeAN3_07540	COG4770	biotin carboxylase activity
AhaeAN3_07550	COG0583	DNA-binding transcription factor activity
AhaeAN3_07610	COG1595	DNA-templated transcription, initiation
AhaeAN3_07615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN3_07625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN3_07630	COG0864	Transcriptional regulator
AhaeAN3_07635	COG0439	Biotin carboxylase
AhaeAN3_07650	COG1522	sequence-specific DNA binding
AhaeAN3_07670	COG1944	ATP diphosphatase activity
AhaeAN3_07700	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_07720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AhaeAN3_07730	COG1063	alcohol dehydrogenase
AhaeAN3_07735	COG2207	Transcriptional regulator
AhaeAN3_07740	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_07755	COG1802	Transcriptional regulator
AhaeAN3_07770	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AhaeAN3_07780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN3_07835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AhaeAN3_07840	COG0148	phosphopyruvate hydratase activity
AhaeAN3_07875	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN3_07875	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN3_07885	COG2267	carboxylic ester hydrolase activity
AhaeAN3_07890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN3_07900	COG0542	response to heat
AhaeAN3_07905	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AhaeAN3_07935	COG1451	nucleotide metabolic process
AhaeAN3_07940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AhaeAN3_07945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AhaeAN3_07950	COG0569	domain protein
AhaeAN3_07955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN3_07975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AhaeAN3_08000	COG1294	oxidase, subunit
AhaeAN3_08005	COG4890	Cyd operon protein YbgT
AhaeAN3_08030	COG0552	protein localization to endoplasmic reticulum
AhaeAN3_08055	COG0517	IMP dehydrogenase activity
AhaeAN3_08055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN3_08060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN3_08065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AhaeAN3_08075	COG0583	DNA-binding transcription factor activity
AhaeAN3_08080	COG0024	Methionine aminopeptidase
AhaeAN3_08125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AhaeAN3_08130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AhaeAN3_08145	COG2801	Transposase and inactivated derivatives
AhaeAN3_08150	COG2431	L-lysine efflux transmembrane transporter activity
AhaeAN3_08165	COG0776	regulation of translation
AhaeAN3_08230	COG0084	hydrolase, TatD family'
AhaeAN3_08255	COG1663	tetraacyldisaccharide 4'-kinase activity
AhaeAN3_08260	COG1132	(ABC) transporter
AhaeAN3_08270	COG0811	peptide transport
AhaeAN3_08275	COG1475	DNA binding
AhaeAN3_08280	COG1192	Involved in chromosome partitioning
AhaeAN3_08290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AhaeAN3_08305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN3_08315	COG0513	Belongs to the DEAD box helicase family
AhaeAN3_08335	COG2363	Small membrane protein
AhaeAN3_08375	COG3550	peptidyl-serine autophosphorylation
AhaeAN3_08385	COG2195	Cleaves the N-terminal amino acid of tripeptides
AhaeAN3_08415	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN3_08420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN3_08425	COG2011	ABC-type metal ion transport system permease component
AhaeAN3_08430	COG0012	GTP binding
AhaeAN3_08440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN3_08445	COG1253	flavin adenine dinucleotide binding
AhaeAN3_08455	COG1942	4-Oxalocrotonate Tautomerase
AhaeAN3_08470	COG0436	Aminotransferase
AhaeAN3_08480	COG1522	sequence-specific DNA binding
AhaeAN3_08485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_08495	COG0386	Belongs to the glutathione peroxidase family
AhaeAN3_08500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN3_08505	COG0436	Aminotransferase
AhaeAN3_08555	COG3042	response to heat
AhaeAN3_08565	COG1278	Cold shock
AhaeAN3_08575	COG1278	Cold shock
AhaeAN3_08595	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AhaeAN3_08595	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AhaeAN3_08655	COG2801	Transposase and inactivated derivatives
AhaeAN3_08665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AhaeAN3_08685	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_08695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AhaeAN3_08720	COG3501	Rhs element vgr protein
AhaeAN3_08725	COG3293	Transposase
AhaeAN3_08730	COG3139	Protein of unknown function (DUF1315)
AhaeAN3_08735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AhaeAN3_08740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AhaeAN3_08750	COG0494	nUDIX hydrolase
AhaeAN3_08760	COG0642	Histidine kinase
AhaeAN3_08765	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_08775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AhaeAN3_08780	COG1720	tRNA m6t6A37 methyltransferase activity
AhaeAN3_08815	COG0583	DNA-binding transcription factor activity
AhaeAN3_08820	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AhaeAN3_08830	COG2814	Major facilitator Superfamily
AhaeAN3_08835	COG4607	ABC-type enterochelin transport system periplasmic component
AhaeAN3_08840	COG4604	ABC transporter, ATP-binding protein
AhaeAN3_08845	COG4605	iron ion homeostasis
AhaeAN3_08850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AhaeAN3_08860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN3_08865	COG0471	metal ion transport
AhaeAN3_08875	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_08895	COG0729	surface antigen
AhaeAN3_08920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AhaeAN3_08955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN3_09015	COG3676	manually curated
AhaeAN3_09020	COG1131	(ABC) transporter
AhaeAN3_09025	COG0842	Transport permease protein
AhaeAN3_09040	COG0772	Belongs to the SEDS family
AhaeAN3_09045	COG2951	lytic endotransglycosylase activity
AhaeAN3_09070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AhaeAN3_09085	COG1643	Atp-dependent helicase
AhaeAN3_09090	COG0450	alkyl hydroperoxide reductase
AhaeAN3_09100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN3_09120	COG3634	alkyl hydroperoxide reductase activity
AhaeAN3_09140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AhaeAN3_09155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN3_09165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AhaeAN3_09165	COG0519	Catalyzes the synthesis of GMP from XMP
AhaeAN3_09175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN3_09185	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN3_09195	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN3_09205	COG0697	spore germination
AhaeAN3_09210	COG1923	regulation of RNA biosynthetic process
AhaeAN3_09220	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AhaeAN3_09225	COG0802	atpase or kinase
AhaeAN3_09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN3_09260	COG3300	MHYT domain
AhaeAN3_09260	COG5001	Diguanylate cyclase
AhaeAN3_09280	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AhaeAN3_09285	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AhaeAN3_09290	COG1845	cytochrome c oxidase, subunit III
AhaeAN3_09295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AhaeAN3_09320	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN3_09325	COG1733	regulation of RNA biosynthetic process
AhaeAN3_09330	COG0305	Participates in initiation and elongation during chromosome replication
AhaeAN3_09335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AhaeAN3_09345	COG3328	transposase activity
AhaeAN3_09360	COG1305	Transglutaminase-like
AhaeAN3_09370	COG2308	Evidence 4 Homologs of previously reported genes of
AhaeAN3_09385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AhaeAN3_09405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AhaeAN3_09415	COG0527	aspartate kinase activity
AhaeAN3_09425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AhaeAN3_09435	COG3038	cytochrome b561
AhaeAN3_09440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AhaeAN3_09445	COG2252	PERMEase
AhaeAN3_09500	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AhaeAN3_09505	COG0138	bifunctional purine biosynthesis protein purh
AhaeAN3_09510	COG0151	Belongs to the GarS family
AhaeAN3_09515	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN3_09520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN3_09525	COG2011	ABC-type metal ion transport system permease component
AhaeAN3_09550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AhaeAN3_09555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AhaeAN3_09560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AhaeAN3_09585	COG0052	Belongs to the universal ribosomal protein uS2 family
AhaeAN3_09590	COG0024	Methionine aminopeptidase
AhaeAN3_09610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN3_09615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN3_09620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN3_09625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN3_09660	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AhaeAN3_09665	COG3161	chorismate lyase activity
AhaeAN3_09670	COG0174	glutamine synthetase
AhaeAN3_09675	COG0512	Glutamine amidotransferase of anthranilate synthase
AhaeAN3_09685	COG0633	Ferredoxin
AhaeAN3_09685	COG3217	Mosc domain protein beta barrel domain protein
AhaeAN3_09710	COG0302	gtp cyclohydrolase
AhaeAN3_09730	COG3739	integral membrane protein
AhaeAN3_09745	COG5001	Diguanylate cyclase
AhaeAN3_09745	COG2203	Gaf domain
AhaeAN3_09745	COG3706	GGDEF domain
AhaeAN3_09745	COG4251	negative regulation of phosphorylation
AhaeAN3_09755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN3_09770	COG4172	Belongs to the ABC transporter superfamily
AhaeAN3_09775	COG4239	(ABC) transporter, permease
AhaeAN3_09780	COG4174	ABC transporter (Permease)
AhaeAN3_09785	COG4166	transmembrane transport
AhaeAN3_09790	COG0741	lytic transglycosylase activity
AhaeAN3_09790	COG0741	lytic transglycosylase activity
AhaeAN3_09790	COG1388	LysM domain
AhaeAN3_09790	COG1388	LysM domain
AhaeAN3_09795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN3_09805	COG2816	NAD+ diphosphatase activity
AhaeAN3_09835	COG0583	DNA-binding transcription factor activity
AhaeAN3_09840	COG1279	arginine transmembrane transporter activity
AhaeAN3_09850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN3_09855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN3_09860	COG0006	proline dipeptidase activity
AhaeAN3_09890	COG2217	Heavy metal translocating P-type atpase
AhaeAN3_09945	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_09955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AhaeAN3_09970	COG3328	transposase activity
AhaeAN3_09975	COG3384	dioxygenase
AhaeAN3_09985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN3_10015	COG3501	Rhs element vgr protein
AhaeAN3_10020	COG2878	Part of a membrane complex involved in electron transport
AhaeAN3_10025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AhaeAN3_10050	COG0768	penicillin binding
AhaeAN3_10055	COG0742	ribosomal rna small subunit methyltransferase
AhaeAN3_10080	COG0616	signal peptide processing
AhaeAN3_10085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AhaeAN3_10095	COG0573	inorganic phosphate transmembrane transporter activity
AhaeAN3_10110	COG0076	glutamate decarboxylase activity
AhaeAN3_10115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN3_10155	COG0783	Belongs to the Dps family
AhaeAN3_10165	COG0564	pseudouridine synthase activity
AhaeAN3_10180	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN3_10210	COG0612	Peptidase, M16
AhaeAN3_10215	COG0384	phenazine biosynthesis protein PhzF
AhaeAN3_10250	COG1686	Belongs to the peptidase S11 family
AhaeAN3_10255	COG1252	NADH dehydrogenase
AhaeAN3_10265	COG0415	Belongs to the DNA photolyase family
AhaeAN3_10290	COG2197	response regulator
AhaeAN3_10295	COG4585	Histidine kinase
AhaeAN3_10310	COG0457	Tetratricopeptide repeat
AhaeAN3_10310	COG0705	Rhomboid family
AhaeAN3_10320	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AhaeAN3_10325	COG4181	ATPase activity
AhaeAN3_10335	COG0456	acetyltransferase
AhaeAN3_10375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AhaeAN3_10400	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AhaeAN3_10405	COG1597	lipid kinase activity
AhaeAN3_10425	COG4773	Receptor
AhaeAN3_10440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AhaeAN3_10450	COG2388	GCN5-related N-acetyl-transferase
AhaeAN3_10495	COG4681	YaeQ
AhaeAN3_10500	COG0523	cobalamin synthesis protein
AhaeAN3_10510	COG1607	acyl-coa hydrolase
AhaeAN3_10530	COG2814	Major facilitator Superfamily
AhaeAN3_10535	COG1024	Enoyl-CoA hydratase
AhaeAN3_10540	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN3_10550	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_10570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN3_10575	COG1414	Transcriptional regulator
AhaeAN3_10585	COG0281	malic enzyme
AhaeAN3_10590	COG0833	amino acid
AhaeAN3_10605	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN3_10615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN3_10620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN3_10630	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_10635	COG1454	alcohol dehydrogenase
AhaeAN3_10645	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_10675	COG0625	glutathione transferase activity
AhaeAN3_10700	COG2814	Major facilitator Superfamily
AhaeAN3_10705	COG1566	PFAM secretion protein HlyD family protein
AhaeAN3_10710	COG2050	protein possibly involved in aromatic compounds catabolism
AhaeAN3_10720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AhaeAN3_10725	COG1090	epimerase
AhaeAN3_10745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AhaeAN3_10750	COG0420	3'-5' exonuclease activity
AhaeAN3_10780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AhaeAN3_10785	COG2914	Belongs to the UPF0125 (RnfH) family
AhaeAN3_10800	COG0121	glutamine amidotransferase
AhaeAN3_10815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN3_10820	COG0756	dUTP diphosphatase activity
AhaeAN3_10825	COG0210	DNA helicase
AhaeAN3_10830	COG2885	chlorophyll binding
AhaeAN3_10835	COG0204	Acyl-transferase
AhaeAN3_10845	COG0850	regulation of cytokinetic process
AhaeAN3_10850	COG2894	cell division
AhaeAN3_10855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AhaeAN3_10865	COG1280	lysine exporter protein (LysE YggA)
AhaeAN3_10870	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AhaeAN3_10870	COG1674	ftsk spoiiie
AhaeAN3_10875	COG0492	ferredoxin-NADP+ reductase activity
AhaeAN3_10880	COG0500	methyltransferase
AhaeAN3_10885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AhaeAN3_10895	COG0456	acetyltransferase
AhaeAN3_10910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN3_10920	COG0049	tRNA binding
AhaeAN3_10950	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN3_10950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AhaeAN3_10975	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AhaeAN3_10985	COG0582	viral genome integration into host DNA
AhaeAN3_11000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN3_11045	COG2132	Multicopper oxidase
AhaeAN3_11060	COG2205	protein histidine kinase activity
AhaeAN3_11065	COG2217	Heavy metal translocating P-type atpase
AhaeAN3_11175	COG0564	pseudouridine synthase activity
AhaeAN3_11185	COG0358	DNA primase activity
AhaeAN3_11200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AhaeAN3_11215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AhaeAN3_11250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AhaeAN3_11260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN3_11260	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN3_11260	COG0351	phosphomethylpyrimidine kinase
AhaeAN3_11270	COG1652	LysM domain
AhaeAN3_11295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AhaeAN3_11300	COG1399	metal-binding, possibly nucleic acid-binding protein
AhaeAN3_11305	COG3101	peptidyl-lysine hydroxylation
AhaeAN3_11310	COG0009	L-threonylcarbamoyladenylate synthase
AhaeAN3_11330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AhaeAN3_11335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AhaeAN3_11355	COG0601	transmembrane transport
AhaeAN3_11365	COG0747	negative chemotaxis
AhaeAN3_11375	COG4771	TonB-dependent receptor
AhaeAN3_11415	COG4106	trans-aconitate 2-methyltransferase activity
AhaeAN3_11430	COG2226	methyltransferase
AhaeAN3_11430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AhaeAN3_11430	COG0596	Alpha beta hydrolase
AhaeAN3_11435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN3_11450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AhaeAN3_11460	COG1196	nuclear chromosome segregation
AhaeAN3_11470	COG0730	response to heat
AhaeAN3_11490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AhaeAN3_11545	COG2358	TRAP transporter, solute receptor (TAXI family
AhaeAN3_11560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AhaeAN3_11565	COG0489	protein tyrosine kinase activity
AhaeAN3_11585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN3_11585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN3_11595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AhaeAN3_11615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AhaeAN3_11620	COG2081	HI0933 family
AhaeAN3_11625	COG0668	transmembrane transport
AhaeAN3_11645	COG0583	DNA-binding transcription factor activity
AhaeAN3_11670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN3_11675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN3_11690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN3_11705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AhaeAN3_11715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN3_11715	COG0649	NAD binding
AhaeAN3_11725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN3_11740	COG2205	protein histidine kinase activity
AhaeAN3_11745	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_11760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AhaeAN3_11795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AhaeAN3_11800	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AhaeAN3_11805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AhaeAN3_11810	COG2076	Multidrug Resistance protein
AhaeAN3_11830	COG2132	Multicopper oxidase
AhaeAN3_11840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AhaeAN3_11865	COG1968	undecaprenyl-diphosphatase activity
AhaeAN3_11870	COG1214	PFAM Peptidase M22, glycoprotease
AhaeAN3_11880	COG0494	nUDIX hydrolase
AhaeAN3_11930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AhaeAN3_11940	COG1595	DNA-templated transcription, initiation
AhaeAN3_11945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AhaeAN3_11950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AhaeAN3_12015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN3_12025	COG1764	response to oxidative stress
AhaeAN3_12050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN3_12050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN3_12065	COG0037	tRNA processing
AhaeAN3_12075	COG0248	Ppx GppA phosphatase
AhaeAN3_12100	COG0072	phenylalanine-tRNA ligase activity
AhaeAN3_12135	COG1238	metal cluster binding
AhaeAN3_12150	COG0625	glutathione transferase activity
AhaeAN3_12170	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN3_12175	COG3028	Belongs to the UPF0307 family
AhaeAN3_12200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AhaeAN3_12205	COG0617	tRNA 3'-terminal CCA addition
AhaeAN3_12210	COG1555	photosystem II stabilization
AhaeAN3_12215	COG3956	TIGRFAM MazG family protein
AhaeAN3_12265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN3_12285	COG0784	Response regulator, receiver
AhaeAN3_12285	COG2205	protein histidine kinase activity
AhaeAN3_12285	COG5002	protein histidine kinase activity
AhaeAN3_12290	COG1024	Enoyl-CoA hydratase
AhaeAN3_12295	COG2084	Dehydrogenase
AhaeAN3_12300	COG3622	Belongs to the hyi family
AhaeAN3_12315	COG0004	ammonium transporteR
AhaeAN3_12355	COG2814	Major facilitator Superfamily
AhaeAN3_12360	COG5285	phytanoyl-CoA dioxygenase
AhaeAN3_12365	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN3_12375	COG0456	acetyltransferase
AhaeAN3_12385	COG0431	NADPH-dependent FMN reductase
AhaeAN3_12390	COG0798	PFAM Bile acid sodium symporter
AhaeAN3_12400	COG0640	Transcriptional regulator
AhaeAN3_12420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AhaeAN3_12430	COG0732	type I restriction modification DNA specificity domain
AhaeAN3_12440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AhaeAN3_12460	COG0174	glutamine synthetase
AhaeAN3_12475	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_12480	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AhaeAN3_12490	COG0745	RESPONSE REGULATOR receiver
AhaeAN3_12495	COG2205	protein histidine kinase activity
AhaeAN3_12505	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AhaeAN3_12510	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AhaeAN3_12590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AhaeAN3_12600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AhaeAN3_12610	COG0084	hydrolase, TatD family'
AhaeAN3_12615	COG0726	polysaccharide deacetylase
AhaeAN3_12625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AhaeAN3_12680	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AhaeAN3_12705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AhaeAN3_12710	COG0440	acetolactate synthase activity
AhaeAN3_12715	COG0028	Belongs to the TPP enzyme family
AhaeAN3_12735	COG1466	dna polymerase III delta subunit
AhaeAN3_12740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_12745	COG0577	efflux transmembrane transporter activity
AhaeAN3_12745	COG1136	(ABC) transporter
AhaeAN3_12750	COG1538	Outer membrane efflux protein
AhaeAN3_12775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AhaeAN3_12780	COG1162	GTPase activity
AhaeAN3_12825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AhaeAN3_12835	COG3781	membrane
AhaeAN3_12870	COG1666	GTP binding
AhaeAN3_12885	COG1956	GAF domain-containing protein
AhaeAN3_12890	COG1607	acyl-coa hydrolase
AhaeAN3_12945	COG1183	phosphatidylcholine synthase activity
AhaeAN3_12950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AhaeAN3_12980	COG1196	nuclear chromosome segregation
AhaeAN3_12980	COG0741	lytic transglycosylase activity
AhaeAN3_12980	COG0739	heme binding
AhaeAN3_12990	COG1702	phosphate starvation-inducible protein PhoH
AhaeAN3_13030	COG3878	Protein conserved in bacteria
AhaeAN3_13075	COG0788	formyltetrahydrofolate deformylase activity
AhaeAN3_13100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN3_13100	COG4651	solute:proton antiporter activity
AhaeAN3_13120	COG0210	DNA helicase
AhaeAN3_13150	COG2900	Belongs to the SlyX family
AhaeAN3_13165	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN3_13215	COG0473	3-isopropylmalate dehydrogenase activity
AhaeAN3_13250	COG0494	nUDIX hydrolase
AhaeAN3_13285	COG0625	glutathione transferase activity
AhaeAN3_13300	COG0564	pseudouridine synthase activity
AhaeAN3_13310	COG1530	ribonuclease E activity
AhaeAN3_13315	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN3_13330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AhaeAN3_13340	COG0534	Mate efflux family protein
AhaeAN3_13345	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AhaeAN3_13370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN3_13395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AhaeAN3_13435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AhaeAN3_13450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AhaeAN3_13460	COG0644	oxidoreductase
AhaeAN3_13460	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AhaeAN3_13465	COG0425	Belongs to the sulfur carrier protein TusA family
AhaeAN3_13470	COG4535	Mg2 and Co2 transporter CorC
AhaeAN3_13475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AhaeAN3_13485	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_13500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AhaeAN3_13510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AhaeAN3_13525	COG0789	Transcriptional regulator
AhaeAN3_13530	COG0598	Magnesium transport protein CorA
AhaeAN3_13535	COG1185	polyribonucleotide nucleotidyltransferase activity
AhaeAN3_13540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AhaeAN3_13550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN3_13555	COG1074	ATP-dependent DNA helicase activity
AhaeAN3_13560	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AhaeAN3_13585	COG2226	methyltransferase
AhaeAN3_13610	COG1116	anion transmembrane transporter activity
AhaeAN3_13615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN3_13625	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN3_13640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN3_13640	COG2111	Na H antiporter
AhaeAN3_13645	COG1006	Multisubunit Na H antiporter MnhC subunit
AhaeAN3_13650	COG0651	ATP synthesis coupled electron transport
AhaeAN3_13655	COG1863	multisubunit Na H antiporter MnhE subunit
AhaeAN3_13660	COG2212	antiporter activity
AhaeAN3_13685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AhaeAN3_13695	COG0195	Participates in both transcription termination and antitermination
AhaeAN3_13745	COG0237	dephospho-CoA kinase activity
AhaeAN3_13760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN3_13770	COG0497	DNA recombination
AhaeAN3_13780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AhaeAN3_13805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AhaeAN3_13845	COG1132	(ABC) transporter
AhaeAN3_13855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AhaeAN3_13870	COG0326	Molecular chaperone. Has ATPase activity
AhaeAN3_13880	COG2056	Na+-H+ antiporter family
AhaeAN3_13930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AhaeAN3_13940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AhaeAN3_13950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN3_13980	COG0546	phosphoglycolate phosphatase activity
AhaeAN3_13985	COG1716	ATPase activity
AhaeAN3_14030	COG0181	hydroxymethylbilane synthase activity
AhaeAN3_14040	COG3275	phosphorelay sensor kinase activity
AhaeAN3_14090	COG0494	nUDIX hydrolase
AhaeAN3_14100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AhaeAN3_14105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN3_14110	COG0772	Belongs to the SEDS family
AhaeAN3_14135	COG4974	Belongs to the 'phage' integrase family
AhaeAN3_14140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN3_14150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AhaeAN3_14155	COG1686	Belongs to the peptidase S11 family
AhaeAN3_14160	COG2197	response regulator
AhaeAN3_14175	COG0793	Belongs to the peptidase S41A family
AhaeAN3_14180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AhaeAN3_14185	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN3_14190	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN3_14230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN3_14230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN3_14235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AhaeAN3_14240	COG0004	ammonium transporteR
AhaeAN3_14245	COG0347	Belongs to the P(II) protein family
AhaeAN3_14325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN3_14330	COG1230	cation diffusion facilitator family transporter
AhaeAN3_14340	COG0640	Transcriptional regulator
AhaeAN3_14350	COG0789	Transcriptional regulator
AhaeAN3_14380	COG2814	Major facilitator Superfamily
AhaeAN3_14420	COG0633	Ferredoxin
AhaeAN3_14465	COG0606	chelatase, subunit chli
AhaeAN3_14505	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN3_14515	COG2860	membrane
AhaeAN3_14525	COG1253	flavin adenine dinucleotide binding
AhaeAN3_14545	COG2814	Major facilitator Superfamily
AhaeAN3_14555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AhaeAN3_14580	COG2814	Major facilitator Superfamily
AhaeAN3_14590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AhaeAN3_14600	COG1283	sodium-dependent phosphate transmembrane transporter activity
AhaeAN3_14630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AhaeAN3_14645	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN3_14650	COG3162	membrane
AhaeAN3_14655	COG2205	protein histidine kinase activity
AhaeAN3_14680	COG1652	LysM domain
AhaeAN3_14685	COG0758	DNA mediated transformation
AhaeAN3_14700	COG1309	transcriptional regulator
AhaeAN3_14705	COG2814	Major facilitator Superfamily
AhaeAN3_14715	COG0386	Belongs to the glutathione peroxidase family
AhaeAN3_14740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AhaeAN3_14750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AhaeAN3_14790	COG1121	(ABC) transporter
AhaeAN3_14795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AhaeAN3_14800	COG1280	lysine exporter protein (LysE YggA)
AhaeAN3_14805	COG2837	iron assimilation
AhaeAN3_14840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN3_14870	COG0519	Catalyzes the synthesis of GMP from XMP
AhaeAN3_14870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AhaeAN3_14875	COG4399	Belongs to the UPF0754 family
AhaeAN3_14885	COG2259	Doxx family
AhaeAN3_14890	COG0586	Pfam SNARE associated Golgi protein
AhaeAN3_14905	COG1192	Involved in chromosome partitioning
AhaeAN3_14915	COG0271	Belongs to the BolA IbaG family
AhaeAN3_14950	COG3756	Protein conserved in bacteria
AhaeAN3_14980	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AhaeAN3_14985	COG0270	DNA (cytosine-5-)-methyltransferase activity
AhaeAN3_15050	COG3550	peptidyl-serine autophosphorylation
AhaeAN3_15055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AhaeAN3_15100	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_15105	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AhaeAN3_15115	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_15155	COG0582	viral genome integration into host DNA
AhaeAN3_15170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN3_15170	COG2885	chlorophyll binding
AhaeAN3_15190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AhaeAN3_15200	COG4115	mRNA cleavage
AhaeAN3_15215	COG0477	Major facilitator Superfamily
AhaeAN3_15220	COG1024	Enoyl-CoA hydratase
AhaeAN3_15225	COG1024	Enoyl-CoA hydratase
AhaeAN3_15230	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_15235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN3_15255	COG1113	amino acid transport
AhaeAN3_15260	COG0251	oxidation-reduction process
AhaeAN3_15285	COG0456	acetyltransferase
AhaeAN3_15295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AhaeAN3_15315	COG2826	transposase and inactivated derivatives, IS30 family
AhaeAN3_15325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AhaeAN3_15345	COG1802	Transcriptional regulator
AhaeAN3_15350	COG1448	Aminotransferase
AhaeAN3_15355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN3_15360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AhaeAN3_15375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AhaeAN3_15385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AhaeAN3_15395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AhaeAN3_15410	COG1216	Glycosyl transferase, family 2
AhaeAN3_15430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AhaeAN3_15465	COG3023	N-Acetylmuramoyl-L-alanine amidase
AhaeAN3_15515	COG0546	phosphoglycolate phosphatase activity
AhaeAN3_15520	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN3_15530	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AhaeAN3_15530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AhaeAN3_15535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN3_15540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN3_15545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN3_15550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN3_15555	COG1116	anion transmembrane transporter activity
AhaeAN3_15560	COG1309	transcriptional regulator
AhaeAN3_15580	COG2801	Transposase and inactivated derivatives
AhaeAN3_15600	COG0196	riboflavin kinase activity
AhaeAN3_15605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AhaeAN3_15615	COG1047	Peptidyl-prolyl cis-trans
AhaeAN3_15655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AhaeAN3_15680	COG0583	DNA-binding transcription factor activity
AhaeAN3_15690	COG0443	Heat shock 70 kDa protein
AhaeAN3_15695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AhaeAN3_15720	COG2951	lytic endotransglycosylase activity
AhaeAN3_15725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AhaeAN3_15745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AhaeAN3_15765	COG1960	acyl-CoA dehydrogenase activity
AhaeAN3_15775	COG0861	Integral membrane protein TerC family
AhaeAN3_15780	COG0402	S-adenosylhomocysteine deaminase activity
AhaeAN3_15795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN3_15810	COG0706	membrane insertase activity
AhaeAN3_15845	COG2184	nucleotidyltransferase activity
AhaeAN3_15860	COG2801	Transposase and inactivated derivatives
AhaeAN3_15875	COG0543	2 iron, 2 sulfur cluster binding
AhaeAN3_15875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AhaeAN3_15880	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AhaeAN3_15885	COG4638	Rieske (2fe-2S)
AhaeAN3_15925	COG1192	Involved in chromosome partitioning
AhaeAN3_15935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AhaeAN3_15955	COG2801	Transposase and inactivated derivatives
AhaeAN3_15985	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AhaeAN3_16100	COG1252	NADH dehydrogenase
AhaeAN3_16105	COG0627	Serine hydrolase involved in the detoxification of formaldehyde