locus-tag	class	description
AhaeAN59_00010	COG0592	DNA-directed DNA polymerase activity
AhaeAN59_00020	COG0187	DNA topoisomerase II activity
AhaeAN59_00025	COG0586	Pfam SNARE associated Golgi protein
AhaeAN59_00030	COG0488	(ABC) transporter
AhaeAN59_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AhaeAN59_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AhaeAN59_00100	COG0471	metal ion transport
AhaeAN59_00100	COG3273	potassium ion transport
AhaeAN59_00110	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN59_00115	COG3738	Protein conserved in bacteria
AhaeAN59_00125	COG0733	neurotransmitter:sodium symporter activity
AhaeAN59_00165	COG2233	PERMEase
AhaeAN59_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_00195	COG0484	heat shock protein binding
AhaeAN59_00210	COG2814	Major facilitator Superfamily
AhaeAN59_00215	COG0656	L-ascorbic acid biosynthetic process
AhaeAN59_00220	COG0583	DNA-binding transcription factor activity
AhaeAN59_00235	COG1064	alcohol dehydrogenase
AhaeAN59_00240	COG2818	Glycosylase
AhaeAN59_00255	COG1194	a g-specific adenine glycosylase
AhaeAN59_00265	COG5487	UPF0391 membrane protein
AhaeAN59_00270	COG2983	Belongs to the UPF0260 family
AhaeAN59_00275	COG2133	pyrroloquinoline quinone binding
AhaeAN59_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AhaeAN59_00295	COG1228	amidohydrolase
AhaeAN59_00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AhaeAN59_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AhaeAN59_00315	COG1335	isochorismatase
AhaeAN59_00320	COG1522	sequence-specific DNA binding
AhaeAN59_00345	COG0464	growth
AhaeAN59_00355	COG3421	Type III restriction
AhaeAN59_00360	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AhaeAN59_00400	COG0505	Belongs to the CarA family
AhaeAN59_00405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN59_00415	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AhaeAN59_00425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AhaeAN59_00430	COG0235	Class ii aldolase
AhaeAN59_00435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN59_00455	COG4372	Transposase
AhaeAN59_00480	COG3135	benzoate transporter
AhaeAN59_00595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AhaeAN59_00605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AhaeAN59_00610	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AhaeAN59_00615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AhaeAN59_00635	COG0560	Phosphoserine phosphatase
AhaeAN59_00635	COG3830	Belongs to the UPF0237 family
AhaeAN59_00680	COG1278	Cold shock
AhaeAN59_00685	COG0583	DNA-binding transcription factor activity
AhaeAN59_00715	COG0534	Mate efflux family protein
AhaeAN59_00720	COG0436	Aminotransferase
AhaeAN59_00730	COG2733	membrane
AhaeAN59_00745	COG2918	glutathione biosynthetic process
AhaeAN59_00760	COG3150	esterase
AhaeAN59_00805	COG1247	-acetyltransferase
AhaeAN59_00835	COG0625	glutathione transferase activity
AhaeAN59_00855	COG1132	(ABC) transporter
AhaeAN59_00875	COG1393	Belongs to the ArsC family
AhaeAN59_00880	COG0708	Exodeoxyribonuclease III
AhaeAN59_00895	COG0300	oxidoreductase activity
AhaeAN59_00925	COG0386	Belongs to the glutathione peroxidase family
AhaeAN59_00930	COG0189	ligase activity
AhaeAN59_00950	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AhaeAN59_01000	COG2119	membrane
AhaeAN59_01005	COG4774	siderophore transport
AhaeAN59_01010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN59_01010	COG0426	domain, Protein
AhaeAN59_01035	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AhaeAN59_01055	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN59_01060	COG1519	Transferase
AhaeAN59_01070	COG0668	transmembrane transport
AhaeAN59_01080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN59_01135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN59_01145	COG2814	Major facilitator Superfamily
AhaeAN59_01170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN59_01175	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN59_01180	COG1335	isochorismatase
AhaeAN59_01185	COG0583	DNA-binding transcription factor activity
AhaeAN59_01195	COG1335	isochorismatase
AhaeAN59_01205	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AhaeAN59_01260	COG4372	Transposase
AhaeAN59_01285	COG0582	viral genome integration into host DNA
AhaeAN59_01295	COG3158	transport of potassium into the cell
AhaeAN59_01335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AhaeAN59_01365	COG0659	secondary active sulfate transmembrane transporter activity
AhaeAN59_01380	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AhaeAN59_01415	COG0427	acetyl-CoA hydrolase
AhaeAN59_01420	COG2205	protein histidine kinase activity
AhaeAN59_01425	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_01450	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN59_01455	COG0583	DNA-binding transcription factor activity
AhaeAN59_01465	COG0789	Transcriptional regulator
AhaeAN59_01470	COG3320	Male sterility
AhaeAN59_01470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AhaeAN59_01475	COG4221	oxidoreductase activity
AhaeAN59_01480	COG2873	o-acetylhomoserine
AhaeAN59_01485	COG0488	(ABC) transporter
AhaeAN59_01615	COG0484	heat shock protein binding
AhaeAN59_01635	COG2801	Transposase and inactivated derivatives
AhaeAN59_01665	COG0833	amino acid
AhaeAN59_01720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AhaeAN59_01725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AhaeAN59_01730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AhaeAN59_01735	COG2226	methyltransferase
AhaeAN59_01785	COG0067	glutamate synthase
AhaeAN59_01785	COG0070	glutamate synthase
AhaeAN59_01785	COG0069	glutamate synthase activity
AhaeAN59_01790	COG0493	'glutamate synthase
AhaeAN59_01810	COG1704	LemA family
AhaeAN59_01815	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AhaeAN59_01830	COG1487	ribonuclease activity
AhaeAN59_01860	COG4636	protein conserved in cyanobacteria
AhaeAN59_01865	COG3307	-O-antigen
AhaeAN59_01885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN59_01895	COG0194	GDP metabolic process
AhaeAN59_01900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AhaeAN59_01905	COG4969	Belongs to the N-Me-Phe pilin family
AhaeAN59_01970	COG0228	four-way junction DNA binding
AhaeAN59_01975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AhaeAN59_01985	COG0335	large ribosomal subunit rRNA binding
AhaeAN59_01995	COG5380	lipid catabolic process
AhaeAN59_02000	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AhaeAN59_02025	COG0739	heme binding
AhaeAN59_02025	COG1196	nuclear chromosome segregation
AhaeAN59_02025	COG0741	lytic transglycosylase activity
AhaeAN59_02030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AhaeAN59_02035	COG0277	FAD linked oxidase domain protein
AhaeAN59_02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AhaeAN59_02055	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN59_02075	COG1289	transmembrane transporter activity
AhaeAN59_02080	COG0628	permease
AhaeAN59_02085	COG1192	Involved in chromosome partitioning
AhaeAN59_02095	COG2226	methyltransferase
AhaeAN59_02135	COG2072	flavoprotein involved in K transport
AhaeAN59_02145	COG1196	nuclear chromosome segregation
AhaeAN59_02180	COG0471	metal ion transport
AhaeAN59_02195	COG1983	PspC domain protein
AhaeAN59_02205	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_02260	COG1127	ABC transporter
AhaeAN59_02265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AhaeAN59_02270	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AhaeAN59_02275	COG2854	intermembrane phospholipid transfer
AhaeAN59_02290	COG0598	Magnesium transport protein CorA
AhaeAN59_02305	COG1040	competence protein
AhaeAN59_02310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AhaeAN59_02330	COG2937	Belongs to the GPAT DAPAT family
AhaeAN59_02335	COG1946	Acyl-CoA thioesterase
AhaeAN59_02340	COG1301	dicarboxylic acid transport
AhaeAN59_02360	COG1959	2 iron, 2 sulfur cluster binding
AhaeAN59_02370	COG0433	COG0433 Predicted ATPase
AhaeAN59_02390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AhaeAN59_02410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AhaeAN59_02460	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AhaeAN59_02540	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_02545	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AhaeAN59_02570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AhaeAN59_02605	COG0557	exoribonuclease II activity
AhaeAN59_02635	COG0179	Fumarylacetoacetate (FAA) hydrolase
AhaeAN59_02640	COG1295	ribonuclease BN
AhaeAN59_02665	COG1785	Belongs to the alkaline phosphatase family
AhaeAN59_02725	COG2813	Specifically methylates the guanine in position
AhaeAN59_02725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AhaeAN59_02735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AhaeAN59_02740	COG4771	TonB-dependent receptor
AhaeAN59_02750	COG0740	serine-type endopeptidase activity
AhaeAN59_02770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN59_02770	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AhaeAN59_02775	COG2207	Transcriptional regulator
AhaeAN59_02775	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN59_02795	COG0280	phosphate acetyltransferase
AhaeAN59_02795	COG0857	belongs to the CobB CobQ family
AhaeAN59_02800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AhaeAN59_02810	COG2267	carboxylic ester hydrolase activity
AhaeAN59_02825	COG0793	Belongs to the peptidase S41A family
AhaeAN59_02845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AhaeAN59_02860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN59_02865	COG1408	metallophosphoesterase
AhaeAN59_02875	COG2199	diguanylate cyclase activity
AhaeAN59_02915	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_02930	COG1309	transcriptional regulator
AhaeAN59_02945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN59_02950	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_03035	COG2969	positive regulation of protein catabolic process
AhaeAN59_03040	COG0625	glutathione transferase activity
AhaeAN59_03045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AhaeAN59_03050	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AhaeAN59_03060	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AhaeAN59_03065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AhaeAN59_03070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AhaeAN59_03085	COG2975	iron-sulfur cluster assembly
AhaeAN59_03105	COG1426	Protein conserved in bacteria
AhaeAN59_03140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AhaeAN59_03150	COG1862	Preprotein translocase
AhaeAN59_03185	COG5002	protein histidine kinase activity
AhaeAN59_03190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AhaeAN59_03200	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AhaeAN59_03210	COG0438	transferase activity, transferring glycosyl groups
AhaeAN59_03280	COG4372	Transposase
AhaeAN59_03295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AhaeAN59_03335	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_03340	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_03350	COG2205	protein histidine kinase activity
AhaeAN59_03355	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_03390	COG2096	Adenosyltransferase
AhaeAN59_03395	COG4206	TonB-dependent receptor
AhaeAN59_03445	COG0285	dihydrofolate synthase activity
AhaeAN59_03460	COG0450	alkyl hydroperoxide reductase
AhaeAN59_03480	COG0477	Major facilitator Superfamily
AhaeAN59_03485	COG1272	protein, Hemolysin III
AhaeAN59_03520	COG0183	Belongs to the thiolase family
AhaeAN59_03535	COG2207	Transcriptional regulator
AhaeAN59_03540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AhaeAN59_03555	COG3501	Rhs element vgr protein
AhaeAN59_03580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN59_03595	COG0183	Belongs to the thiolase family
AhaeAN59_03605	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN59_03605	COG2885	chlorophyll binding
AhaeAN59_03610	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AhaeAN59_03610	COG2885	chlorophyll binding
AhaeAN59_03615	COG1690	Belongs to the RtcB family
AhaeAN59_03620	COG0833	amino acid
AhaeAN59_03630	COG2233	PERMEase
AhaeAN59_03640	COG1970	mechanosensitive ion channel activity
AhaeAN59_03650	COG4372	Transposase
AhaeAN59_03675	COG4772	TonB-dependent receptor
AhaeAN59_03685	COG0354	folic acid binding
AhaeAN59_03695	COG2824	Alkylphosphonate utilization operon protein PhnA
AhaeAN59_03700	COG3422	double-strand break repair
AhaeAN59_03730	COG0840	transmembrane signaling receptor activity
AhaeAN59_03735	COG2198	Histidine kinase
AhaeAN59_03735	COG0643	Histidine kinase
AhaeAN59_03735	COG2198	Histidine kinase
AhaeAN59_03735	COG0643	Histidine kinase
AhaeAN59_03750	COG5510	response to toxic substance
AhaeAN59_03760	COG2832	Protein of unknown function (DUF454)
AhaeAN59_03765	COG1376	ErfK ybiS ycfS ynhG family protein
AhaeAN59_03810	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AhaeAN59_03820	COG2985	domain, Protein
AhaeAN59_03830	COG1289	transmembrane transporter activity
AhaeAN59_03835	COG2814	Major facilitator Superfamily
AhaeAN59_03850	COG0786	glutamate:sodium symporter activity
AhaeAN59_03855	COG1115	amino acid carrier protein
AhaeAN59_03860	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN59_03865	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AhaeAN59_03920	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN59_03935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN59_03945	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AhaeAN59_03950	COG1077	Cell shape determining protein MreB Mrl
AhaeAN59_03955	COG1792	Involved in formation and maintenance of cell shape
AhaeAN59_03965	COG0424	maF-like protein
AhaeAN59_03970	COG1530	ribonuclease E activity
AhaeAN59_03980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN59_03990	COG0560	Phosphoserine phosphatase
AhaeAN59_04010	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN59_04020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AhaeAN59_04045	COG1113	amino acid transport
AhaeAN59_04050	COG2828	Protein conserved in bacteria
AhaeAN59_04055	COG0142	geranyltranstransferase activity
AhaeAN59_04070	COG1752	Esterase of the alpha-beta hydrolase superfamily
AhaeAN59_04150	COG2194	sulfuric ester hydrolase activity
AhaeAN59_04155	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_04160	COG0642	Histidine kinase
AhaeAN59_04170	COG1126	abc transporter atp-binding protein
AhaeAN59_04175	COG0765	amino acid transport
AhaeAN59_04180	COG0765	amino acid transport
AhaeAN59_04190	COG0004	ammonium transporteR
AhaeAN59_04210	COG0525	valine-tRNA ligase activity
AhaeAN59_04225	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN59_04235	COG0393	Putative heavy-metal-binding
AhaeAN59_04240	COG0393	Putative heavy-metal-binding
AhaeAN59_04245	COG1538	Outer membrane efflux protein
AhaeAN59_04255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_04260	COG0671	phosphoesterase, PA-phosphatase related
AhaeAN59_04290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AhaeAN59_04305	COG1648	precorrin-2 dehydrogenase activity
AhaeAN59_04305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AhaeAN59_04310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AhaeAN59_04320	COG1733	regulation of RNA biosynthetic process
AhaeAN59_04330	COG0531	amino acid
AhaeAN59_04345	COG0321	lipoyl(octanoyl) transferase activity
AhaeAN59_04375	COG1280	lysine exporter protein (LysE YggA)
AhaeAN59_04385	COG0500	methyltransferase
AhaeAN59_04390	COG0586	Pfam SNARE associated Golgi protein
AhaeAN59_04410	COG2009	succinate dehydrogenase
AhaeAN59_04415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AhaeAN59_04420	COG1053	succinate dehydrogenase
AhaeAN59_04425	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AhaeAN59_04445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN59_04460	COG2268	Band 7 protein
AhaeAN59_04465	COG1585	Membrane protein implicated in regulation of membrane protease activity
AhaeAN59_04475	COG2354	Protein conserved in bacteria
AhaeAN59_04480	COG2321	neutral zinc metallopeptidase
AhaeAN59_04540	COG0110	maltose O-acetyltransferase activity
AhaeAN59_04560	COG0505	Belongs to the CarA family
AhaeAN59_04585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN59_04600	COG2304	oxidoreductase activity
AhaeAN59_04625	COG0584	glycerophosphoryl diester phosphodiesterase
AhaeAN59_04635	COG2194	sulfuric ester hydrolase activity
AhaeAN59_04640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN59_04645	COG2239	Acts as a magnesium transporter
AhaeAN59_04655	COG0501	Belongs to the peptidase M48B family
AhaeAN59_04660	COG1196	nuclear chromosome segregation
AhaeAN59_04660	COG0739	heme binding
AhaeAN59_04660	COG0741	lytic transglycosylase activity
AhaeAN59_04675	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AhaeAN59_04680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AhaeAN59_04690	COG1301	dicarboxylic acid transport
AhaeAN59_04695	COG0583	DNA-binding transcription factor activity
AhaeAN59_04820	COG0725	ABC transporter, periplasmic molybdate-binding protein
AhaeAN59_04825	COG4149	molybdate abc transporter
AhaeAN59_04830	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AhaeAN59_04840	COG4521	taurine ABC transporter
AhaeAN59_04845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AhaeAN59_04850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN59_04855	COG2175	clavaminate synthase activity
AhaeAN59_04885	COG0589	response to stress
AhaeAN59_04900	COG0242	peptide deformylase activity
AhaeAN59_04925	COG0306	phosphate transporter
AhaeAN59_04940	COG1115	amino acid carrier protein
AhaeAN59_04950	COG0019	diaminopimelate decarboxylase activity
AhaeAN59_04955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AhaeAN59_04965	COG1280	lysine exporter protein (LysE YggA)
AhaeAN59_04970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AhaeAN59_05010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_05030	COG1671	Belongs to the UPF0178 family
AhaeAN59_05045	COG4591	ABC-type transport system involved in lipoprotein release permease component
AhaeAN59_05050	COG1136	(ABC) transporter
AhaeAN59_05055	COG2333	competence protein COMEC
AhaeAN59_05055	COG0658	competence protein
AhaeAN59_05065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AhaeAN59_05065	COG0616	signal peptide processing
AhaeAN59_05075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AhaeAN59_05085	COG0628	permease
AhaeAN59_05125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN59_05145	COG0823	Involved in the tonB-independent uptake of proteins
AhaeAN59_05165	COG0824	Thioesterase
AhaeAN59_05175	COG2255	four-way junction helicase activity
AhaeAN59_05195	COG0047	phosphoribosylformylglycinamidine synthase activity
AhaeAN59_05195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AhaeAN59_05215	COG3323	Protein of unknown function (DUF1653)
AhaeAN59_05215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN59_05220	COG0778	Nitroreductase
AhaeAN59_05225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AhaeAN59_05225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN59_05225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AhaeAN59_05230	COG1105	Belongs to the carbohydrate kinase PfkB family
AhaeAN59_05235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AhaeAN59_05235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AhaeAN59_05240	COG1024	Enoyl-CoA hydratase
AhaeAN59_05245	COG1056	cytidyltransferase-related domain
AhaeAN59_05245	COG1051	belongs to the nudix hydrolase family
AhaeAN59_05250	COG0583	DNA-binding transcription factor activity
AhaeAN59_05255	COG1942	4-Oxalocrotonate Tautomerase
AhaeAN59_05275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN59_05290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AhaeAN59_05295	COG0602	queuosine metabolic process
AhaeAN59_05310	COG0583	DNA-binding transcription factor activity
AhaeAN59_05315	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AhaeAN59_05320	COG4208	sulfate ABC transporter
AhaeAN59_05325	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AhaeAN59_05335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AhaeAN59_05340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AhaeAN59_05345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AhaeAN59_05365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN59_05375	COG0481	GTPase activity
AhaeAN59_05390	COG0571	ribonuclease III activity
AhaeAN59_05395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AhaeAN59_05410	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AhaeAN59_05435	COG0436	Aminotransferase
AhaeAN59_05460	COG0556	nucleotide-excision repair
AhaeAN59_05510	COG1840	ABC-type Fe3 transport system, periplasmic component
AhaeAN59_05515	COG3842	ATPase activity
AhaeAN59_05535	COG0583	DNA-binding transcription factor activity
AhaeAN59_05540	COG0596	Alpha beta hydrolase
AhaeAN59_05545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN59_05555	COG1773	rubredoxin
AhaeAN59_05565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AhaeAN59_05580	COG0175	sulfate reduction
AhaeAN59_05600	COG0222	ribosome binding
AhaeAN59_05605	COG1253	flavin adenine dinucleotide binding
AhaeAN59_05620	COG3015	lipoprotein NlpE involved in copper resistance
AhaeAN59_05635	COG0517	IMP dehydrogenase activity
AhaeAN59_05635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN59_05640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AhaeAN59_05650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AhaeAN59_05655	COG1137	ATPase activity
AhaeAN59_05690	COG4122	O-methyltransferase activity
AhaeAN59_05700	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AhaeAN59_05725	COG0583	DNA-binding transcription factor activity
AhaeAN59_05775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AhaeAN59_05795	COG0583	DNA-binding transcription factor activity
AhaeAN59_05835	COG4783	chaperone-mediated protein folding
AhaeAN59_05850	COG1610	YqeY-like protein
AhaeAN59_05935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN59_05940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN59_05945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AhaeAN59_05950	COG4605	iron ion homeostasis
AhaeAN59_05955	COG4604	ABC transporter, ATP-binding protein
AhaeAN59_05970	COG4372	Transposase
AhaeAN59_05995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AhaeAN59_05995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AhaeAN59_06000	COG1021	2,3-dihydroxybenzoate-AMP ligase
AhaeAN59_06005	COG1535	isochorismatase
AhaeAN59_06005	COG3433	isochorismatase activity
AhaeAN59_06015	COG1132	(ABC) transporter
AhaeAN59_06020	COG1132	(ABC) transporter
AhaeAN59_06025	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AhaeAN59_06035	COG1169	isochorismate synthase
AhaeAN59_06040	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN59_06045	COG1414	Transcriptional regulator
AhaeAN59_06050	COG2146	nitrite reductase [NAD(P)H] activity
AhaeAN59_06065	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN59_06100	COG0482	sulfurtransferase activity
AhaeAN59_06115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AhaeAN59_06120	COG1686	Belongs to the peptidase S11 family
AhaeAN59_06140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AhaeAN59_06150	COG0583	DNA-binding transcription factor activity
AhaeAN59_06155	COG1067	ATP-dependent peptidase activity
AhaeAN59_06175	COG0254	rRNA binding
AhaeAN59_06190	COG1509	lysine 2,3-aminomutase activity
AhaeAN59_06195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AhaeAN59_06215	COG2879	small protein
AhaeAN59_06220	COG0714	Associated with various cellular activities
AhaeAN59_06250	COG1741	Belongs to the pirin family
AhaeAN59_06265	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN59_06265	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN59_06295	COG2271	Major facilitator Superfamily
AhaeAN59_06340	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_06350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AhaeAN59_06385	COG1629	transport
AhaeAN59_06390	COG3501	Rhs element vgr protein
AhaeAN59_06450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AhaeAN59_06460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN59_06465	COG1469	GTP cyclohydrolase I activity
AhaeAN59_06480	COG0523	cobalamin synthesis protein
AhaeAN59_06485	COG1414	Transcriptional regulator
AhaeAN59_06490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AhaeAN59_06495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AhaeAN59_06500	COG0183	Belongs to the thiolase family
AhaeAN59_06505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AhaeAN59_06510	COG0596	Alpha beta hydrolase
AhaeAN59_06515	COG2271	Major facilitator Superfamily
AhaeAN59_06520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AhaeAN59_06525	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN59_06530	COG3485	protocatechuate 3,4-dioxygenase
AhaeAN59_06535	COG0710	3-dehydroquinate dehydratase activity
AhaeAN59_06540	COG3420	alginic acid biosynthetic process
AhaeAN59_06545	COG3659	wide pore channel activity
AhaeAN59_06550	COG4993	Dehydrogenase
AhaeAN59_06560	COG2351	hydroxyisourate hydrolase activity
AhaeAN59_06565	COG2233	PERMEase
AhaeAN59_06585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN59_06595	COG4266	Belongs to the allantoicase family
AhaeAN59_06620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN59_06630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN59_06645	COG0583	DNA-binding transcription factor activity
AhaeAN59_06655	COG2188	Transcriptional regulator
AhaeAN59_06680	COG0010	Belongs to the arginase family
AhaeAN59_06685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN59_06690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN59_06735	COG0243	molybdopterin cofactor binding
AhaeAN59_06740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AhaeAN59_06745	COG2837	iron assimilation
AhaeAN59_06755	COG1538	Outer membrane efflux protein
AhaeAN59_06760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN59_06765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_06770	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_06775	COG5002	protein histidine kinase activity
AhaeAN59_06780	COG3040	lipid binding
AhaeAN59_06800	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN59_06810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AhaeAN59_06815	COG0642	Histidine kinase
AhaeAN59_06835	COG1309	transcriptional regulator
AhaeAN59_06855	COG2072	flavoprotein involved in K transport
AhaeAN59_06860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AhaeAN59_06865	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN59_06870	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN59_06875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AhaeAN59_06880	COG4770	biotin carboxylase activity
AhaeAN59_06885	COG0501	Belongs to the peptidase M48B family
AhaeAN59_06895	COG1765	OsmC-like protein
AhaeAN59_06945	COG3501	Rhs element vgr protein
AhaeAN59_06995	COG4133	protoheme IX ABC transporter activity
AhaeAN59_07030	COG0308	aminopeptidase N
AhaeAN59_07035	COG1760	l-serine dehydratase
AhaeAN59_07055	COG1714	RDD family
AhaeAN59_07070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN59_07070	COG0475	glutathione-regulated potassium exporter activity
AhaeAN59_07075	COG3135	benzoate transporter
AhaeAN59_07085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AhaeAN59_07090	COG0583	DNA-binding transcription factor activity
AhaeAN59_07110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AhaeAN59_07140	COG0316	Belongs to the HesB IscA family
AhaeAN59_07145	COG0822	iron-sulfur transferase activity
AhaeAN59_07170	COG0776	regulation of translation
AhaeAN59_07175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN59_07190	COG2137	regulation of response to DNA damage stimulus
AhaeAN59_07200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AhaeAN59_07205	COG1011	Hydrolase
AhaeAN59_07210	COG1218	3'(2'),5'-bisphosphate nucleotidase
AhaeAN59_07230	COG0268	Binds directly to 16S ribosomal RNA
AhaeAN59_07235	COG0702	epimerase
AhaeAN59_07240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AhaeAN59_07280	COG0183	Belongs to the thiolase family
AhaeAN59_07325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AhaeAN59_07330	COG0583	DNA-binding transcription factor activity
AhaeAN59_07335	COG0424	maF-like protein
AhaeAN59_07405	COG1286	toxin biosynthetic process
AhaeAN59_07460	COG3634	alkyl hydroperoxide reductase activity
AhaeAN59_07505	COG0436	Aminotransferase
AhaeAN59_07510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN59_07515	COG0386	Belongs to the glutathione peroxidase family
AhaeAN59_07525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_07530	COG1522	sequence-specific DNA binding
AhaeAN59_07540	COG0436	Aminotransferase
AhaeAN59_07565	COG1253	flavin adenine dinucleotide binding
AhaeAN59_07570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN59_07580	COG0012	GTP binding
AhaeAN59_07585	COG2011	ABC-type metal ion transport system permease component
AhaeAN59_07590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN59_07595	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN59_07625	COG2195	Cleaves the N-terminal amino acid of tripeptides
AhaeAN59_07635	COG3550	peptidyl-serine autophosphorylation
AhaeAN59_07680	COG2363	Small membrane protein
AhaeAN59_07700	COG0513	Belongs to the DEAD box helicase family
AhaeAN59_07710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AhaeAN59_07725	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AhaeAN59_07735	COG1192	Involved in chromosome partitioning
AhaeAN59_07740	COG1475	DNA binding
AhaeAN59_07745	COG0811	peptide transport
AhaeAN59_07755	COG1132	(ABC) transporter
AhaeAN59_07760	COG1663	tetraacyldisaccharide 4'-kinase activity
AhaeAN59_07785	COG0084	hydrolase, TatD family'
AhaeAN59_07850	COG0776	regulation of translation
AhaeAN59_07865	COG2431	L-lysine efflux transmembrane transporter activity
AhaeAN59_07895	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AhaeAN59_07900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AhaeAN59_07950	COG0024	Methionine aminopeptidase
AhaeAN59_07955	COG0583	DNA-binding transcription factor activity
AhaeAN59_07965	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AhaeAN59_07970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN59_07975	COG0517	IMP dehydrogenase activity
AhaeAN59_07975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AhaeAN59_08000	COG0552	protein localization to endoplasmic reticulum
AhaeAN59_08030	COG4890	Cyd operon protein YbgT
AhaeAN59_08035	COG1294	oxidase, subunit
AhaeAN59_08060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AhaeAN59_08095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN59_08100	COG0569	domain protein
AhaeAN59_08105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AhaeAN59_08110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AhaeAN59_08145	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AhaeAN59_08150	COG0542	response to heat
AhaeAN59_08160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN59_08165	COG2267	carboxylic ester hydrolase activity
AhaeAN59_08175	COG0446	pyridine nucleotide-disulphide oxidoreductase
AhaeAN59_08175	COG1902	pentaerythritol trinitrate reductase activity
AhaeAN59_08210	COG0148	phosphopyruvate hydratase activity
AhaeAN59_08215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AhaeAN59_08270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AhaeAN59_08285	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AhaeAN59_08300	COG1802	Transcriptional regulator
AhaeAN59_08325	COG1063	alcohol dehydrogenase
AhaeAN59_08335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AhaeAN59_08385	COG1944	ATP diphosphatase activity
AhaeAN59_08405	COG1522	sequence-specific DNA binding
AhaeAN59_08420	COG0439	Biotin carboxylase
AhaeAN59_08425	COG0864	Transcriptional regulator
AhaeAN59_08430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN59_08440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN59_08445	COG1595	DNA-templated transcription, initiation
AhaeAN59_08505	COG0583	DNA-binding transcription factor activity
AhaeAN59_08515	COG4770	biotin carboxylase activity
AhaeAN59_08520	COG1024	Enoyl-CoA hydratase
AhaeAN59_08525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AhaeAN59_08530	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_08535	COG1309	transcriptional regulator
AhaeAN59_08540	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN59_08555	COG2814	Major facilitator Superfamily
AhaeAN59_08575	COG0583	DNA-binding transcription factor activity
AhaeAN59_08585	COG4774	siderophore transport
AhaeAN59_08630	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN59_08640	COG3706	GGDEF domain
AhaeAN59_08660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AhaeAN59_08680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AhaeAN59_08725	COG0537	adenosine 5'-monophosphoramidase activity
AhaeAN59_08755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN59_08775	COG0730	response to heat
AhaeAN59_08780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AhaeAN59_08790	COG4771	TonB-dependent receptor
AhaeAN59_08810	COG0406	alpha-ribazole phosphatase activity
AhaeAN59_08815	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AhaeAN59_08830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AhaeAN59_08845	COG2814	Major facilitator Superfamily
AhaeAN59_08890	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_08895	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_08900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AhaeAN59_08905	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN59_08925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN59_08960	COG0575	Belongs to the CDS family
AhaeAN59_08965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AhaeAN59_08975	COG0528	UMP kinase activity
AhaeAN59_08985	COG3852	Histidine kinase
AhaeAN59_08990	COG2204	response regulator
AhaeAN59_08995	COG1309	transcriptional regulator
AhaeAN59_09045	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AhaeAN59_09065	COG0697	spore germination
AhaeAN59_09070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AhaeAN59_09080	COG0303	'Molybdopterin
AhaeAN59_09085	COG0521	Mo-molybdopterin cofactor biosynthetic process
AhaeAN59_09085	COG0315	cyclic pyranopterin monophosphate synthase activity
AhaeAN59_09100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AhaeAN59_09105	COG0243	molybdopterin cofactor binding
AhaeAN59_09120	COG0243	molybdopterin cofactor binding
AhaeAN59_09125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN59_09130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AhaeAN59_09130	COG2146	nitrite reductase [NAD(P)H] activity
AhaeAN59_09135	COG2223	nitrite transmembrane transporter activity
AhaeAN59_09145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN59_09145	COG1116	anion transmembrane transporter activity
AhaeAN59_09160	COG0439	Biotin carboxylase
AhaeAN59_09175	COG2814	Major facilitator Superfamily
AhaeAN59_09185	COG0069	glutamate synthase activity
AhaeAN59_09205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AhaeAN59_09215	COG1454	alcohol dehydrogenase
AhaeAN59_09220	COG0824	Thioesterase
AhaeAN59_09230	COG2850	peptidyl-arginine hydroxylation
AhaeAN59_09250	COG0640	Transcriptional regulator
AhaeAN59_09275	COG0668	transmembrane transport
AhaeAN59_09285	COG1132	(ABC) transporter
AhaeAN59_09315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN59_09325	COG0506	proline dehydrogenase activity
AhaeAN59_09325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN59_09325	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AhaeAN59_09330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AhaeAN59_09335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AhaeAN59_09345	COG3698	Phosphodiester glycosidase
AhaeAN59_09360	COG3153	acetyltransferase
AhaeAN59_09365	COG2353	YceI-like domain
AhaeAN59_09380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AhaeAN59_09385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AhaeAN59_09400	COG3042	response to heat
AhaeAN59_09410	COG1278	Cold shock
AhaeAN59_09420	COG1278	Cold shock
AhaeAN59_09440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AhaeAN59_09440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AhaeAN59_09465	COG3539	Fimbrial protein
AhaeAN59_09505	COG0204	Acyl-transferase
AhaeAN59_09525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AhaeAN59_09540	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_09545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AhaeAN59_09565	COG3501	Rhs element vgr protein
AhaeAN59_09570	COG3139	Protein of unknown function (DUF1315)
AhaeAN59_09575	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AhaeAN59_09580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AhaeAN59_09590	COG0494	nUDIX hydrolase
AhaeAN59_09600	COG0642	Histidine kinase
AhaeAN59_09605	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_09615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AhaeAN59_09620	COG1720	tRNA m6t6A37 methyltransferase activity
AhaeAN59_09655	COG0583	DNA-binding transcription factor activity
AhaeAN59_09660	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AhaeAN59_09670	COG2814	Major facilitator Superfamily
AhaeAN59_09675	COG4607	ABC-type enterochelin transport system periplasmic component
AhaeAN59_09680	COG4604	ABC transporter, ATP-binding protein
AhaeAN59_09685	COG4605	iron ion homeostasis
AhaeAN59_09690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AhaeAN59_09700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AhaeAN59_09705	COG0471	metal ion transport
AhaeAN59_09730	COG0729	surface antigen
AhaeAN59_09755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AhaeAN59_09780	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AhaeAN59_09790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN59_09905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AhaeAN59_09915	COG0583	DNA-binding transcription factor activity
AhaeAN59_09920	COG1131	(ABC) transporter
AhaeAN59_09925	COG0842	Transport permease protein
AhaeAN59_09940	COG0772	Belongs to the SEDS family
AhaeAN59_09945	COG2951	lytic endotransglycosylase activity
AhaeAN59_09970	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AhaeAN59_09985	COG1643	Atp-dependent helicase
AhaeAN59_09990	COG0450	alkyl hydroperoxide reductase
AhaeAN59_10000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN59_10020	COG3634	alkyl hydroperoxide reductase activity
AhaeAN59_10040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AhaeAN59_10055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN59_10065	COG0531	amino acid
AhaeAN59_10070	COG4303	Ethanolamine ammonia lyase large subunit
AhaeAN59_10075	COG4302	ethanolamine ammonia-lyase activity
AhaeAN59_10080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AhaeAN59_10080	COG0519	Catalyzes the synthesis of GMP from XMP
AhaeAN59_10085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN59_10095	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AhaeAN59_10105	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN59_10115	COG0697	spore germination
AhaeAN59_10120	COG1923	regulation of RNA biosynthetic process
AhaeAN59_10130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AhaeAN59_10135	COG0802	atpase or kinase
AhaeAN59_10165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN59_10170	COG5001	Diguanylate cyclase
AhaeAN59_10170	COG3300	MHYT domain
AhaeAN59_10190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AhaeAN59_10195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AhaeAN59_10200	COG1845	cytochrome c oxidase, subunit III
AhaeAN59_10205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AhaeAN59_10230	COG2249	NAD(P)H dehydrogenase (quinone) activity
AhaeAN59_10235	COG1733	regulation of RNA biosynthetic process
AhaeAN59_10240	COG0305	Participates in initiation and elongation during chromosome replication
AhaeAN59_10245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AhaeAN59_10260	COG1305	Transglutaminase-like
AhaeAN59_10290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AhaeAN59_10305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AhaeAN59_10315	COG0527	aspartate kinase activity
AhaeAN59_10325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AhaeAN59_10335	COG3038	cytochrome b561
AhaeAN59_10340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AhaeAN59_10345	COG2252	PERMEase
AhaeAN59_10425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AhaeAN59_10430	COG0138	bifunctional purine biosynthesis protein purh
AhaeAN59_10435	COG0151	Belongs to the GarS family
AhaeAN59_10440	COG1464	Belongs to the NlpA lipoprotein family
AhaeAN59_10445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AhaeAN59_10450	COG2011	ABC-type metal ion transport system permease component
AhaeAN59_10475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AhaeAN59_10480	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AhaeAN59_10485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AhaeAN59_10515	COG0052	Belongs to the universal ribosomal protein uS2 family
AhaeAN59_10520	COG0024	Methionine aminopeptidase
AhaeAN59_10530	COG2223	nitrite transmembrane transporter activity
AhaeAN59_10540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AhaeAN59_10545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AhaeAN59_10550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN59_10555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AhaeAN59_10590	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AhaeAN59_10595	COG3161	chorismate lyase activity
AhaeAN59_10600	COG0174	glutamine synthetase
AhaeAN59_10605	COG0512	Glutamine amidotransferase of anthranilate synthase
AhaeAN59_10615	COG3217	Mosc domain protein beta barrel domain protein
AhaeAN59_10615	COG0633	Ferredoxin
AhaeAN59_10640	COG0302	gtp cyclohydrolase
AhaeAN59_10660	COG3739	integral membrane protein
AhaeAN59_10675	COG2203	Gaf domain
AhaeAN59_10675	COG3706	GGDEF domain
AhaeAN59_10675	COG4251	negative regulation of phosphorylation
AhaeAN59_10675	COG5001	Diguanylate cyclase
AhaeAN59_10685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN59_10700	COG4172	Belongs to the ABC transporter superfamily
AhaeAN59_10705	COG4239	(ABC) transporter, permease
AhaeAN59_10710	COG4174	ABC transporter (Permease)
AhaeAN59_10715	COG4166	transmembrane transport
AhaeAN59_10720	COG0741	lytic transglycosylase activity
AhaeAN59_10720	COG0741	lytic transglycosylase activity
AhaeAN59_10720	COG1388	LysM domain
AhaeAN59_10720	COG1388	LysM domain
AhaeAN59_10725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AhaeAN59_10735	COG2816	NAD+ diphosphatase activity
AhaeAN59_10765	COG0583	DNA-binding transcription factor activity
AhaeAN59_10770	COG1279	arginine transmembrane transporter activity
AhaeAN59_10780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN59_10785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN59_10790	COG0006	proline dipeptidase activity
AhaeAN59_10825	COG2217	Heavy metal translocating P-type atpase
AhaeAN59_10840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AhaeAN59_10855	COG3384	dioxygenase
AhaeAN59_10865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN59_10895	COG2878	Part of a membrane complex involved in electron transport
AhaeAN59_10900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AhaeAN59_10925	COG0768	penicillin binding
AhaeAN59_10930	COG0742	ribosomal rna small subunit methyltransferase
AhaeAN59_10955	COG0616	signal peptide processing
AhaeAN59_10960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AhaeAN59_10970	COG0573	inorganic phosphate transmembrane transporter activity
AhaeAN59_10985	COG0076	glutamate decarboxylase activity
AhaeAN59_10990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AhaeAN59_11000	COG4772	TonB-dependent receptor
AhaeAN59_11010	COG1309	transcriptional regulator
AhaeAN59_11040	COG0783	Belongs to the Dps family
AhaeAN59_11050	COG0564	pseudouridine synthase activity
AhaeAN59_11065	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN59_11095	COG0612	Peptidase, M16
AhaeAN59_11100	COG0384	phenazine biosynthesis protein PhzF
AhaeAN59_11140	COG1686	Belongs to the peptidase S11 family
AhaeAN59_11145	COG1252	NADH dehydrogenase
AhaeAN59_11155	COG0415	Belongs to the DNA photolyase family
AhaeAN59_11175	COG1271	oxidase subunit
AhaeAN59_11180	COG1294	oxidase, subunit
AhaeAN59_11200	COG0705	Rhomboid family
AhaeAN59_11200	COG0457	Tetratricopeptide repeat
AhaeAN59_11210	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AhaeAN59_11215	COG4181	ATPase activity
AhaeAN59_11220	COG4372	Transposase
AhaeAN59_11240	COG0456	acetyltransferase
AhaeAN59_11290	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AhaeAN59_11310	COG0582	viral genome integration into host DNA
AhaeAN59_11325	COG0732	type I restriction modification DNA specificity domain
AhaeAN59_11330	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AhaeAN59_11400	COG0174	glutamine synthetase
AhaeAN59_11405	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_11410	COG2205	protein histidine kinase activity
AhaeAN59_11415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AhaeAN59_11420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AhaeAN59_11425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AhaeAN59_11430	COG0569	domain protein
AhaeAN59_11435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AhaeAN59_11450	COG3328	transposase activity
AhaeAN59_11515	COG1484	DNA-dependent DNA replication
AhaeAN59_11520	COG2390	Transcriptional regulator
AhaeAN59_11520	COG4584	PFAM Integrase catalytic
AhaeAN59_11580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AhaeAN59_11585	COG1597	lipid kinase activity
AhaeAN59_11590	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AhaeAN59_11640	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AhaeAN59_11650	COG2388	GCN5-related N-acetyl-transferase
AhaeAN59_11675	COG3152	Membrane
AhaeAN59_11725	COG4681	YaeQ
AhaeAN59_11730	COG0523	cobalamin synthesis protein
AhaeAN59_11740	COG1607	acyl-coa hydrolase
AhaeAN59_11760	COG2814	Major facilitator Superfamily
AhaeAN59_11765	COG1024	Enoyl-CoA hydratase
AhaeAN59_11770	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN59_11780	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN59_11820	COG0281	malic enzyme
AhaeAN59_11825	COG0833	amino acid
AhaeAN59_11840	COG1012	belongs to the aldehyde dehydrogenase family
AhaeAN59_11850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AhaeAN59_11855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AhaeAN59_11865	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_11870	COG1454	alcohol dehydrogenase
AhaeAN59_11875	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AhaeAN59_11900	COG0625	glutathione transferase activity
AhaeAN59_11925	COG2814	Major facilitator Superfamily
AhaeAN59_11930	COG1566	PFAM secretion protein HlyD family protein
AhaeAN59_11935	COG2050	protein possibly involved in aromatic compounds catabolism
AhaeAN59_11945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AhaeAN59_11950	COG1090	epimerase
AhaeAN59_11965	COG1024	Enoyl-CoA hydratase
AhaeAN59_12000	COG0420	3'-5' exonuclease activity
AhaeAN59_12040	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AhaeAN59_12045	COG2914	Belongs to the UPF0125 (RnfH) family
AhaeAN59_12060	COG0121	glutamine amidotransferase
AhaeAN59_12075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN59_12080	COG0756	dUTP diphosphatase activity
AhaeAN59_12085	COG0210	DNA helicase
AhaeAN59_12090	COG2885	chlorophyll binding
AhaeAN59_12095	COG0204	Acyl-transferase
AhaeAN59_12105	COG0850	regulation of cytokinetic process
AhaeAN59_12110	COG2894	cell division
AhaeAN59_12115	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AhaeAN59_12125	COG1280	lysine exporter protein (LysE YggA)
AhaeAN59_12130	COG1674	ftsk spoiiie
AhaeAN59_12130	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AhaeAN59_12135	COG0492	ferredoxin-NADP+ reductase activity
AhaeAN59_12140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AhaeAN59_12150	COG0456	acetyltransferase
AhaeAN59_12165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN59_12175	COG0049	tRNA binding
AhaeAN59_12210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AhaeAN59_12210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN59_12235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AhaeAN59_12245	COG0582	viral genome integration into host DNA
AhaeAN59_12265	COG4372	Transposase
AhaeAN59_12280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AhaeAN59_12335	COG2132	Multicopper oxidase
AhaeAN59_12350	COG2205	protein histidine kinase activity
AhaeAN59_12355	COG2217	Heavy metal translocating P-type atpase
AhaeAN59_12375	COG4372	Transposase
AhaeAN59_12480	COG0564	pseudouridine synthase activity
AhaeAN59_12490	COG0358	DNA primase activity
AhaeAN59_12510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AhaeAN59_12525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AhaeAN59_12560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AhaeAN59_12570	COG0351	phosphomethylpyrimidine kinase
AhaeAN59_12570	COG0352	thiamine-phosphate diphosphorylase activity
AhaeAN59_12570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AhaeAN59_12580	COG1652	LysM domain
AhaeAN59_12605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AhaeAN59_12610	COG1399	metal-binding, possibly nucleic acid-binding protein
AhaeAN59_12615	COG3101	peptidyl-lysine hydroxylation
AhaeAN59_12620	COG0009	L-threonylcarbamoyladenylate synthase
AhaeAN59_12640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AhaeAN59_12645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AhaeAN59_12675	COG0747	negative chemotaxis
AhaeAN59_12720	COG4106	trans-aconitate 2-methyltransferase activity
AhaeAN59_12740	COG0596	Alpha beta hydrolase
AhaeAN59_12750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AhaeAN59_12765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AhaeAN59_12775	COG1196	nuclear chromosome segregation
AhaeAN59_12785	COG0730	response to heat
AhaeAN59_12805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AhaeAN59_12840	COG4372	Transposase
AhaeAN59_12895	COG2358	TRAP transporter, solute receptor (TAXI family
AhaeAN59_12915	COG0489	protein tyrosine kinase activity
AhaeAN59_12935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN59_12935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AhaeAN59_12945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AhaeAN59_12965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AhaeAN59_12970	COG2081	HI0933 family
AhaeAN59_12975	COG0668	transmembrane transport
AhaeAN59_12995	COG0583	DNA-binding transcription factor activity
AhaeAN59_13020	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN59_13025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN59_13040	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN59_13055	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AhaeAN59_13065	COG0649	NAD binding
AhaeAN59_13065	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN59_13075	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AhaeAN59_13090	COG2205	protein histidine kinase activity
AhaeAN59_13095	COG0745	RESPONSE REGULATOR receiver
AhaeAN59_13110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AhaeAN59_13140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AhaeAN59_13145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AhaeAN59_13150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AhaeAN59_13155	COG2076	Multidrug Resistance protein
AhaeAN59_13175	COG2132	Multicopper oxidase
AhaeAN59_13185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AhaeAN59_13210	COG1968	undecaprenyl-diphosphatase activity
AhaeAN59_13215	COG1214	PFAM Peptidase M22, glycoprotease
AhaeAN59_13225	COG0494	nUDIX hydrolase
AhaeAN59_13265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AhaeAN59_13275	COG1595	DNA-templated transcription, initiation
AhaeAN59_13280	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AhaeAN59_13285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AhaeAN59_13350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AhaeAN59_13360	COG1764	response to oxidative stress
AhaeAN59_13385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN59_13385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AhaeAN59_13400	COG0037	tRNA processing
AhaeAN59_13410	COG0248	Ppx GppA phosphatase
AhaeAN59_13435	COG0072	phenylalanine-tRNA ligase activity
AhaeAN59_13465	COG1238	metal cluster binding
AhaeAN59_13480	COG0625	glutathione transferase activity
AhaeAN59_13500	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN59_13505	COG3028	Belongs to the UPF0307 family
AhaeAN59_13530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AhaeAN59_13535	COG0617	tRNA 3'-terminal CCA addition
AhaeAN59_13540	COG1555	photosystem II stabilization
AhaeAN59_13545	COG3956	TIGRFAM MazG family protein
AhaeAN59_13560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AhaeAN59_13580	COG0784	Response regulator, receiver
AhaeAN59_13580	COG2205	protein histidine kinase activity
AhaeAN59_13580	COG5002	protein histidine kinase activity
AhaeAN59_13585	COG1024	Enoyl-CoA hydratase
AhaeAN59_13590	COG2084	Dehydrogenase
AhaeAN59_13595	COG3622	Belongs to the hyi family
AhaeAN59_13640	COG2814	Major facilitator Superfamily
AhaeAN59_13645	COG5285	phytanoyl-CoA dioxygenase
AhaeAN59_13650	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN59_13660	COG0456	acetyltransferase
AhaeAN59_13670	COG0431	NADPH-dependent FMN reductase
AhaeAN59_13675	COG0798	PFAM Bile acid sodium symporter
AhaeAN59_13685	COG0640	Transcriptional regulator
AhaeAN59_13700	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AhaeAN59_13710	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AhaeAN59_13725	COG0084	hydrolase, TatD family'
AhaeAN59_13740	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AhaeAN59_13745	COG3177	Filamentation induced by cAMP protein fic
AhaeAN59_13750	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AhaeAN59_13960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AhaeAN59_13965	COG0440	acetolactate synthase activity
AhaeAN59_13970	COG0028	Belongs to the TPP enzyme family
AhaeAN59_13990	COG1466	dna polymerase III delta subunit
AhaeAN59_13995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_14000	COG1136	(ABC) transporter
AhaeAN59_14000	COG0577	efflux transmembrane transporter activity
AhaeAN59_14005	COG1538	Outer membrane efflux protein
AhaeAN59_14030	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AhaeAN59_14035	COG1162	GTPase activity
AhaeAN59_14045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AhaeAN59_14080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AhaeAN59_14090	COG3781	membrane
AhaeAN59_14125	COG1666	GTP binding
AhaeAN59_14140	COG1956	GAF domain-containing protein
AhaeAN59_14145	COG1607	acyl-coa hydrolase
AhaeAN59_14210	COG1183	phosphatidylcholine synthase activity
AhaeAN59_14215	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AhaeAN59_14245	COG0739	heme binding
AhaeAN59_14245	COG0741	lytic transglycosylase activity
AhaeAN59_14245	COG1196	nuclear chromosome segregation
AhaeAN59_14255	COG1702	phosphate starvation-inducible protein PhoH
AhaeAN59_14270	COG4773	Receptor
AhaeAN59_14335	COG0788	formyltetrahydrofolate deformylase activity
AhaeAN59_14360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AhaeAN59_14360	COG4651	solute:proton antiporter activity
AhaeAN59_14385	COG0210	DNA helicase
AhaeAN59_14410	COG1733	regulation of RNA biosynthetic process
AhaeAN59_14420	COG2900	Belongs to the SlyX family
AhaeAN59_14435	COG1560	Kdo2-lipid A biosynthetic process
AhaeAN59_14485	COG0473	3-isopropylmalate dehydrogenase activity
AhaeAN59_14520	COG0494	nUDIX hydrolase
AhaeAN59_14555	COG0625	glutathione transferase activity
AhaeAN59_14570	COG0564	pseudouridine synthase activity
AhaeAN59_14580	COG1530	ribonuclease E activity
AhaeAN59_14585	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN59_14600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AhaeAN59_14610	COG0534	Mate efflux family protein
AhaeAN59_14615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AhaeAN59_14640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN59_14665	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AhaeAN59_14705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AhaeAN59_14720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AhaeAN59_14730	COG0644	oxidoreductase
AhaeAN59_14730	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AhaeAN59_14735	COG0425	Belongs to the sulfur carrier protein TusA family
AhaeAN59_14740	COG4535	Mg2 and Co2 transporter CorC
AhaeAN59_14745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AhaeAN59_14765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AhaeAN59_14775	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AhaeAN59_14790	COG0789	Transcriptional regulator
AhaeAN59_14795	COG0598	Magnesium transport protein CorA
AhaeAN59_14800	COG1185	polyribonucleotide nucleotidyltransferase activity
AhaeAN59_14805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AhaeAN59_14815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AhaeAN59_14820	COG1074	ATP-dependent DNA helicase activity
AhaeAN59_14825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AhaeAN59_14850	COG2226	methyltransferase
AhaeAN59_14875	COG1116	anion transmembrane transporter activity
AhaeAN59_14880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AhaeAN59_14890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AhaeAN59_14905	COG2111	Na H antiporter
AhaeAN59_14905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AhaeAN59_14910	COG1006	Multisubunit Na H antiporter MnhC subunit
AhaeAN59_14915	COG0651	ATP synthesis coupled electron transport
AhaeAN59_14920	COG1863	multisubunit Na H antiporter MnhE subunit
AhaeAN59_14925	COG2212	antiporter activity
AhaeAN59_14950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AhaeAN59_14960	COG0195	Participates in both transcription termination and antitermination
AhaeAN59_15020	COG0237	dephospho-CoA kinase activity
AhaeAN59_15035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AhaeAN59_15045	COG0497	DNA recombination
AhaeAN59_15055	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AhaeAN59_15080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AhaeAN59_15135	COG1132	(ABC) transporter
AhaeAN59_15145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AhaeAN59_15160	COG0326	Molecular chaperone. Has ATPase activity
AhaeAN59_15170	COG2056	Na+-H+ antiporter family
AhaeAN59_15220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AhaeAN59_15230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AhaeAN59_15240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AhaeAN59_15270	COG0546	phosphoglycolate phosphatase activity
AhaeAN59_15275	COG1716	ATPase activity
AhaeAN59_15330	COG0181	hydroxymethylbilane synthase activity
AhaeAN59_15340	COG3275	phosphorelay sensor kinase activity
AhaeAN59_15370	COG0494	nUDIX hydrolase
AhaeAN59_15380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AhaeAN59_15385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AhaeAN59_15390	COG0772	Belongs to the SEDS family
AhaeAN59_15415	COG4974	Belongs to the 'phage' integrase family
AhaeAN59_15420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN59_15430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AhaeAN59_15435	COG1686	Belongs to the peptidase S11 family
AhaeAN59_15440	COG2197	response regulator
AhaeAN59_15455	COG0793	Belongs to the peptidase S41A family
AhaeAN59_15460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AhaeAN59_15465	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN59_15470	COG0795	lipopolysaccharide-transporting ATPase activity
AhaeAN59_15505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN59_15505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AhaeAN59_15510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AhaeAN59_15515	COG0004	ammonium transporteR
AhaeAN59_15520	COG0347	Belongs to the P(II) protein family
AhaeAN59_15640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AhaeAN59_15645	COG1230	cation diffusion facilitator family transporter
AhaeAN59_15660	COG0640	Transcriptional regulator
AhaeAN59_15665	COG2217	Heavy metal translocating P-type atpase
AhaeAN59_15670	COG0789	Transcriptional regulator
AhaeAN59_15680	COG4372	Transposase
AhaeAN59_15740	COG2814	Major facilitator Superfamily
AhaeAN59_15780	COG0633	Ferredoxin
AhaeAN59_15830	COG0606	chelatase, subunit chli
AhaeAN59_15865	COG0318	PFAM AMP-dependent synthetase and ligase
AhaeAN59_15885	COG2860	membrane
AhaeAN59_15895	COG1253	flavin adenine dinucleotide binding
AhaeAN59_15915	COG2814	Major facilitator Superfamily
AhaeAN59_15925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AhaeAN59_15965	COG2814	Major facilitator Superfamily
AhaeAN59_15975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AhaeAN59_15985	COG1283	sodium-dependent phosphate transmembrane transporter activity
AhaeAN59_16015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AhaeAN59_16030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AhaeAN59_16035	COG3162	membrane
AhaeAN59_16040	COG2205	protein histidine kinase activity
AhaeAN59_16065	COG1652	LysM domain
AhaeAN59_16070	COG0758	DNA mediated transformation
AhaeAN59_16085	COG1309	transcriptional regulator
AhaeAN59_16090	COG2814	Major facilitator Superfamily
AhaeAN59_16100	COG0386	Belongs to the glutathione peroxidase family
AhaeAN59_16125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AhaeAN59_16135	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AhaeAN59_16175	COG1121	(ABC) transporter
AhaeAN59_16180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AhaeAN59_16185	COG1280	lysine exporter protein (LysE YggA)
AhaeAN59_16190	COG2837	iron assimilation
AhaeAN59_16225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AhaeAN59_16255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AhaeAN59_16255	COG0519	Catalyzes the synthesis of GMP from XMP
AhaeAN59_16260	COG4399	Belongs to the UPF0754 family
AhaeAN59_16270	COG2259	Doxx family
AhaeAN59_16275	COG0586	Pfam SNARE associated Golgi protein
AhaeAN59_16290	COG1192	Involved in chromosome partitioning
AhaeAN59_16300	COG0271	Belongs to the BolA IbaG family
AhaeAN59_16330	COG3756	Protein conserved in bacteria
AhaeAN59_16385	COG0270	DNA (cytosine-5-)-methyltransferase activity
AhaeAN59_16450	COG3550	peptidyl-serine autophosphorylation
AhaeAN59_16515	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AhaeAN59_16590	COG0735	belongs to the Fur family
AhaeAN59_16630	COG0477	Major facilitator Superfamily
AhaeAN59_16635	COG1024	Enoyl-CoA hydratase
AhaeAN59_16640	COG1024	Enoyl-CoA hydratase
AhaeAN59_16645	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_16650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AhaeAN59_16670	COG1113	amino acid transport
AhaeAN59_16675	COG0251	oxidation-reduction process
AhaeAN59_16705	COG0456	acetyltransferase
AhaeAN59_16715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AhaeAN59_16750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AhaeAN59_16770	COG1802	Transcriptional regulator
AhaeAN59_16775	COG1448	Aminotransferase
AhaeAN59_16780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AhaeAN59_16785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AhaeAN59_16800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AhaeAN59_16810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AhaeAN59_16820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AhaeAN59_16825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AhaeAN59_16870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AhaeAN59_16905	COG3023	N-Acetylmuramoyl-L-alanine amidase
AhaeAN59_16955	COG0546	phosphoglycolate phosphatase activity
AhaeAN59_16960	COG1028	Short-chain dehydrogenase reductase Sdr
AhaeAN59_16970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AhaeAN59_16970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AhaeAN59_16975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN59_16980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AhaeAN59_16985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AhaeAN59_16990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AhaeAN59_16995	COG1116	anion transmembrane transporter activity
AhaeAN59_17000	COG1309	transcriptional regulator
AhaeAN59_17005	COG4372	Transposase
AhaeAN59_17030	COG2801	Transposase and inactivated derivatives
AhaeAN59_17045	COG0196	riboflavin kinase activity
AhaeAN59_17050	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AhaeAN59_17060	COG1047	Peptidyl-prolyl cis-trans
AhaeAN59_17100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AhaeAN59_17125	COG0583	DNA-binding transcription factor activity
AhaeAN59_17135	COG0443	Heat shock 70 kDa protein
AhaeAN59_17140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AhaeAN59_17165	COG2951	lytic endotransglycosylase activity
AhaeAN59_17170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AhaeAN59_17190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AhaeAN59_17210	COG1960	acyl-CoA dehydrogenase activity
AhaeAN59_17220	COG0861	Integral membrane protein TerC family
AhaeAN59_17230	COG0402	S-adenosylhomocysteine deaminase activity
AhaeAN59_17245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AhaeAN59_17255	COG0706	membrane insertase activity
AhaeAN59_17330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AhaeAN59_17335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AhaeAN59_17400	COG1917	Cupin 2, conserved barrel domain protein
AhaeAN59_17400	COG4977	sequence-specific DNA binding
AhaeAN59_17405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN59_17410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AhaeAN59_17415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN59_17425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AhaeAN59_17430	COG3706	GGDEF domain
AhaeAN59_17445	COG2369	cell adhesion
AhaeAN59_17450	COG0582	viral genome integration into host DNA
AhaeAN59_17475	COG0789	Transcriptional regulator
AhaeAN59_17510	COG1373	ATPase (AAA superfamily
AhaeAN59_17630	COG0789	Transcriptional regulator
AhaeAN59_17660	COG4716	Myosin-crossreactive antigen
AhaeAN59_17665	COG1063	alcohol dehydrogenase
AhaeAN59_17690	COG0154	amidase activity