locus-tag	class	description
AHTJR_00010	COG0592	DNA-directed DNA polymerase activity
AHTJR_00020	COG0187	DNA topoisomerase II activity
AHTJR_00025	COG0586	Pfam SNARE associated Golgi protein
AHTJR_00030	COG0488	(ABC) transporter
AHTJR_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AHTJR_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AHTJR_00100	COG0471	metal ion transport
AHTJR_00100	COG3273	potassium ion transport
AHTJR_00110	COG1012	belongs to the aldehyde dehydrogenase family
AHTJR_00115	COG3738	Protein conserved in bacteria
AHTJR_00125	COG0733	neurotransmitter:sodium symporter activity
AHTJR_00165	COG2233	PERMEase
AHTJR_00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_00195	COG0484	heat shock protein binding
AHTJR_00215	COG0656	L-ascorbic acid biosynthetic process
AHTJR_00220	COG0583	DNA-binding transcription factor activity
AHTJR_00235	COG1064	alcohol dehydrogenase
AHTJR_00240	COG2818	Glycosylase
AHTJR_00255	COG1194	a g-specific adenine glycosylase
AHTJR_00265	COG5487	UPF0391 membrane protein
AHTJR_00270	COG2983	Belongs to the UPF0260 family
AHTJR_00275	COG2133	pyrroloquinoline quinone binding
AHTJR_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AHTJR_00295	COG1228	amidohydrolase
AHTJR_00300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AHTJR_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AHTJR_00315	COG1335	isochorismatase
AHTJR_00320	COG1522	sequence-specific DNA binding
AHTJR_00330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AHTJR_00340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AHTJR_00345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AHTJR_00350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AHTJR_00370	COG0560	Phosphoserine phosphatase
AHTJR_00370	COG3830	Belongs to the UPF0237 family
AHTJR_00415	COG1278	Cold shock
AHTJR_00455	COG0534	Mate efflux family protein
AHTJR_00460	COG0436	Aminotransferase
AHTJR_00470	COG2733	membrane
AHTJR_00485	COG2918	glutathione biosynthetic process
AHTJR_00500	COG3150	esterase
AHTJR_00510	COG0534	Mate efflux family protein
AHTJR_00520	COG0559	Belongs to the binding-protein-dependent transport system permease family
AHTJR_00535	COG0410	ABC transporter
AHTJR_00545	COG1247	-acetyltransferase
AHTJR_00575	COG0625	glutathione transferase activity
AHTJR_00580	COG1132	(ABC) transporter
AHTJR_00600	COG1393	Belongs to the ArsC family
AHTJR_00605	COG0708	Exodeoxyribonuclease III
AHTJR_00635	COG0386	Belongs to the glutathione peroxidase family
AHTJR_00640	COG0189	ligase activity
AHTJR_00660	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AHTJR_00710	COG2119	membrane
AHTJR_00715	COG4774	siderophore transport
AHTJR_00720	COG0426	domain, Protein
AHTJR_00720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHTJR_00745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AHTJR_00775	COG1902	pentaerythritol trinitrate reductase activity
AHTJR_00780	COG1519	Transferase
AHTJR_00790	COG0668	transmembrane transport
AHTJR_00795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHTJR_00860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AHTJR_00860	COG0351	phosphomethylpyrimidine kinase
AHTJR_00860	COG0352	thiamine-phosphate diphosphorylase activity
AHTJR_00870	COG2814	Major facilitator Superfamily
AHTJR_00895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AHTJR_00900	COG1012	belongs to the aldehyde dehydrogenase family
AHTJR_00910	COG1335	isochorismatase
AHTJR_00920	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AHTJR_00945	COG3177	Filamentation induced by cAMP protein fic
AHTJR_01050	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_01075	COG0582	viral genome integration into host DNA
AHTJR_01085	COG3158	transport of potassium into the cell
AHTJR_01100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AHTJR_01120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AHTJR_01140	COG0659	secondary active sulfate transmembrane transporter activity
AHTJR_01160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AHTJR_01195	COG0427	acetyl-CoA hydrolase
AHTJR_01200	COG2205	protein histidine kinase activity
AHTJR_01205	COG0745	RESPONSE REGULATOR receiver
AHTJR_01235	COG1028	Short-chain dehydrogenase reductase Sdr
AHTJR_01240	COG0583	DNA-binding transcription factor activity
AHTJR_01265	COG4221	oxidoreductase activity
AHTJR_01275	COG0488	(ABC) transporter
AHTJR_01345	COG0833	amino acid
AHTJR_01370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AHTJR_01390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AHTJR_01395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AHTJR_01400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AHTJR_01405	COG2226	methyltransferase
AHTJR_01455	COG0067	glutamate synthase
AHTJR_01455	COG0069	glutamate synthase activity
AHTJR_01455	COG0070	glutamate synthase
AHTJR_01460	COG0493	'glutamate synthase
AHTJR_01470	COG1704	LemA family
AHTJR_01475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AHTJR_01510	COG2755	lipolytic protein G-D-S-L family
AHTJR_01510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AHTJR_01525	COG3307	-O-antigen
AHTJR_01535	COG2906	2 iron, 2 sulfur cluster binding
AHTJR_01545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHTJR_01555	COG0194	GDP metabolic process
AHTJR_01560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AHTJR_01590	COG4969	Belongs to the N-Me-Phe pilin family
AHTJR_01630	COG0228	four-way junction DNA binding
AHTJR_01635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AHTJR_01645	COG0335	large ribosomal subunit rRNA binding
AHTJR_01655	COG5380	lipid catabolic process
AHTJR_01660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AHTJR_01680	COG5006	permease, DMT superfamily
AHTJR_01685	COG0741	lytic transglycosylase activity
AHTJR_01685	COG0739	heme binding
AHTJR_01685	COG1196	nuclear chromosome segregation
AHTJR_01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AHTJR_01695	COG0277	FAD linked oxidase domain protein
AHTJR_01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AHTJR_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHTJR_01730	COG1289	transmembrane transporter activity
AHTJR_01735	COG0628	permease
AHTJR_01740	COG1192	Involved in chromosome partitioning
AHTJR_01750	COG2226	methyltransferase
AHTJR_01790	COG2072	flavoprotein involved in K transport
AHTJR_01830	COG0471	metal ion transport
AHTJR_01840	COG1983	PspC domain protein
AHTJR_01850	COG1960	acyl-CoA dehydrogenase activity
AHTJR_01865	COG0406	alpha-ribazole phosphatase activity
AHTJR_01890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AHTJR_01900	COG1127	ABC transporter
AHTJR_01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AHTJR_01910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AHTJR_01915	COG2854	intermembrane phospholipid transfer
AHTJR_01930	COG0598	Magnesium transport protein CorA
AHTJR_01945	COG1040	competence protein
AHTJR_01950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AHTJR_01965	COG2937	Belongs to the GPAT DAPAT family
AHTJR_01970	COG1946	Acyl-CoA thioesterase
AHTJR_02000	COG1017	nitric oxide dioxygenase activity
AHTJR_02000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHTJR_02005	COG0433	COG0433 Predicted ATPase
AHTJR_02025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AHTJR_02045	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AHTJR_02095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AHTJR_02130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AHTJR_02140	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AHTJR_02155	COG0203	ribosomal protein L17
AHTJR_02175	COG1960	acyl-CoA dehydrogenase activity
AHTJR_02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AHTJR_02205	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AHTJR_02230	COG0339	signal peptide processing
AHTJR_02235	COG0557	exoribonuclease II activity
AHTJR_02285	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
AHTJR_02335	COG2207	Transcriptional regulator
AHTJR_02345	COG1295	ribonuclease BN
AHTJR_02375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AHTJR_02400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHTJR_02400	COG2813	Specifically methylates the guanine in position
AHTJR_02410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHTJR_02415	COG4771	TonB-dependent receptor
AHTJR_02425	COG0740	serine-type endopeptidase activity
AHTJR_02445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AHTJR_02445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AHTJR_02450	COG1917	Cupin 2, conserved barrel domain protein
AHTJR_02450	COG2207	Transcriptional regulator
AHTJR_02455	COG0697	spore germination
AHTJR_02470	COG0280	phosphate acetyltransferase
AHTJR_02470	COG0857	belongs to the CobB CobQ family
AHTJR_02475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AHTJR_02500	COG0793	Belongs to the peptidase S41A family
AHTJR_02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AHTJR_02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHTJR_02535	COG1408	metallophosphoesterase
AHTJR_02545	COG2199	diguanylate cyclase activity
AHTJR_02585	COG1960	acyl-CoA dehydrogenase activity
AHTJR_02600	COG1309	transcriptional regulator
AHTJR_02615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AHTJR_02620	COG1960	acyl-CoA dehydrogenase activity
AHTJR_02645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AHTJR_02650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AHTJR_02655	COG0625	glutathione transferase activity
AHTJR_02660	COG2969	positive regulation of protein catabolic process
AHTJR_02710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AHTJR_02715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AHTJR_02720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AHTJR_02740	COG2975	iron-sulfur cluster assembly
AHTJR_02760	COG1426	Protein conserved in bacteria
AHTJR_02795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AHTJR_02805	COG1862	Preprotein translocase
AHTJR_02840	COG5002	protein histidine kinase activity
AHTJR_02845	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AHTJR_02855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AHTJR_02900	COG0463	Glycosyl transferase, family 2
AHTJR_02900	COG1216	Glycosyl transferase, family 2
AHTJR_02925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AHTJR_02945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AHTJR_02985	COG1960	acyl-CoA dehydrogenase activity
AHTJR_02990	COG1960	acyl-CoA dehydrogenase activity
AHTJR_03000	COG2205	protein histidine kinase activity
AHTJR_03005	COG0745	RESPONSE REGULATOR receiver
AHTJR_03040	COG2096	Adenosyltransferase
AHTJR_03045	COG4206	TonB-dependent receptor
AHTJR_03055	COG0133	tryptophan synthase activity
AHTJR_03095	COG0285	dihydrofolate synthase activity
AHTJR_03110	COG0450	alkyl hydroperoxide reductase
AHTJR_03130	COG0477	Major facilitator Superfamily
AHTJR_03135	COG1272	protein, Hemolysin III
AHTJR_03170	COG0183	Belongs to the thiolase family
AHTJR_03180	COG2207	Transcriptional regulator
AHTJR_03185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AHTJR_03215	COG0739	heme binding
AHTJR_03230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHTJR_03245	COG0183	Belongs to the thiolase family
AHTJR_03255	COG2885	chlorophyll binding
AHTJR_03255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AHTJR_03265	COG2885	chlorophyll binding
AHTJR_03265	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AHTJR_03270	COG1690	Belongs to the RtcB family
AHTJR_03275	COG0833	amino acid
AHTJR_03285	COG2233	PERMEase
AHTJR_03300	COG1970	mechanosensitive ion channel activity
AHTJR_03320	COG4772	TonB-dependent receptor
AHTJR_03330	COG0354	folic acid binding
AHTJR_03340	COG2824	Alkylphosphonate utilization operon protein PhnA
AHTJR_03345	COG3422	double-strand break repair
AHTJR_03375	COG0840	transmembrane signaling receptor activity
AHTJR_03380	COG0643	Histidine kinase
AHTJR_03380	COG0643	Histidine kinase
AHTJR_03380	COG2198	Histidine kinase
AHTJR_03380	COG2198	Histidine kinase
AHTJR_03395	COG5510	response to toxic substance
AHTJR_03405	COG2832	Protein of unknown function (DUF454)
AHTJR_03410	COG1376	ErfK ybiS ycfS ynhG family protein
AHTJR_03465	COG1289	transmembrane transporter activity
AHTJR_03485	COG0786	glutamate:sodium symporter activity
AHTJR_03490	COG1115	amino acid carrier protein
AHTJR_03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
AHTJR_03500	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AHTJR_03545	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHTJR_03555	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AHTJR_03560	COG1077	Cell shape determining protein MreB Mrl
AHTJR_03565	COG1792	Involved in formation and maintenance of cell shape
AHTJR_03575	COG0424	maF-like protein
AHTJR_03580	COG1530	ribonuclease E activity
AHTJR_03590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AHTJR_03620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AHTJR_03625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AHTJR_03630	COG2205	protein histidine kinase activity
AHTJR_03635	COG0745	RESPONSE REGULATOR receiver
AHTJR_03645	COG0671	phosphoesterase, PA-phosphatase related
AHTJR_03655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AHTJR_03680	COG1113	amino acid transport
AHTJR_03690	COG0142	geranyltranstransferase activity
AHTJR_03705	COG1752	Esterase of the alpha-beta hydrolase superfamily
AHTJR_03730	COG2194	sulfuric ester hydrolase activity
AHTJR_03735	COG0745	RESPONSE REGULATOR receiver
AHTJR_03740	COG0642	Histidine kinase
AHTJR_03750	COG1126	abc transporter atp-binding protein
AHTJR_03755	COG0765	amino acid transport
AHTJR_03760	COG0765	amino acid transport
AHTJR_03785	COG2852	Protein conserved in bacteria
AHTJR_03805	COG0525	valine-tRNA ligase activity
AHTJR_03820	COG1028	Short-chain dehydrogenase reductase Sdr
AHTJR_03830	COG0393	Putative heavy-metal-binding
AHTJR_03835	COG0393	Putative heavy-metal-binding
AHTJR_03840	COG1538	Outer membrane efflux protein
AHTJR_03850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_03855	COG0671	phosphoesterase, PA-phosphatase related
AHTJR_03885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AHTJR_03900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AHTJR_03900	COG1648	precorrin-2 dehydrogenase activity
AHTJR_03905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AHTJR_03915	COG1733	regulation of RNA biosynthetic process
AHTJR_03925	COG0531	amino acid
AHTJR_03940	COG0321	lipoyl(octanoyl) transferase activity
AHTJR_03980	COG0500	methyltransferase
AHTJR_03985	COG0586	Pfam SNARE associated Golgi protein
AHTJR_04005	COG2009	succinate dehydrogenase
AHTJR_04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AHTJR_04015	COG1053	succinate dehydrogenase
AHTJR_04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AHTJR_04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHTJR_04055	COG2268	Band 7 protein
AHTJR_04060	COG1585	Membrane protein implicated in regulation of membrane protease activity
AHTJR_04070	COG2354	Protein conserved in bacteria
AHTJR_04075	COG2321	neutral zinc metallopeptidase
AHTJR_04115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AHTJR_04145	COG0110	maltose O-acetyltransferase activity
AHTJR_04165	COG0505	Belongs to the CarA family
AHTJR_04190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHTJR_04200	COG2304	oxidoreductase activity
AHTJR_04225	COG0584	glycerophosphoryl diester phosphodiesterase
AHTJR_04230	COG2194	sulfuric ester hydrolase activity
AHTJR_04250	COG2239	Acts as a magnesium transporter
AHTJR_04260	COG0501	Belongs to the peptidase M48B family
AHTJR_04265	COG1196	nuclear chromosome segregation
AHTJR_04265	COG0741	lytic transglycosylase activity
AHTJR_04265	COG0739	heme binding
AHTJR_04280	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AHTJR_04285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AHTJR_04315	COG0725	ABC transporter, periplasmic molybdate-binding protein
AHTJR_04320	COG4149	molybdate abc transporter
AHTJR_04340	COG4521	taurine ABC transporter
AHTJR_04345	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AHTJR_04350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHTJR_04355	COG2175	clavaminate synthase activity
AHTJR_04385	COG0589	response to stress
AHTJR_04400	COG0242	peptide deformylase activity
AHTJR_04405	COG2852	Protein conserved in bacteria
AHTJR_04430	COG0306	phosphate transporter
AHTJR_04460	COG1115	amino acid carrier protein
AHTJR_04470	COG0019	diaminopimelate decarboxylase activity
AHTJR_04475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AHTJR_04485	COG1280	lysine exporter protein (LysE YggA)
AHTJR_04490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AHTJR_04530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_04560	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AHTJR_04570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AHTJR_04760	COG1671	Belongs to the UPF0178 family
AHTJR_04775	COG4591	ABC-type transport system involved in lipoprotein release permease component
AHTJR_04780	COG1136	(ABC) transporter
AHTJR_04785	COG2333	competence protein COMEC
AHTJR_04785	COG0658	competence protein
AHTJR_04795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AHTJR_04795	COG0616	signal peptide processing
AHTJR_04805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AHTJR_04815	COG0628	permease
AHTJR_04855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHTJR_04875	COG0823	Involved in the tonB-independent uptake of proteins
AHTJR_04895	COG0824	Thioesterase
AHTJR_04905	COG2255	four-way junction helicase activity
AHTJR_04920	COG0047	phosphoribosylformylglycinamidine synthase activity
AHTJR_04920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AHTJR_04930	COG3323	Protein of unknown function (DUF1653)
AHTJR_04930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHTJR_04935	COG0778	Nitroreductase
AHTJR_04940	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AHTJR_04940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHTJR_04940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AHTJR_04945	COG1105	Belongs to the carbohydrate kinase PfkB family
AHTJR_04950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AHTJR_04950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AHTJR_04955	COG1024	Enoyl-CoA hydratase
AHTJR_04960	COG1056	cytidyltransferase-related domain
AHTJR_04960	COG1051	belongs to the nudix hydrolase family
AHTJR_04965	COG0583	DNA-binding transcription factor activity
AHTJR_04970	COG1942	4-Oxalocrotonate Tautomerase
AHTJR_04990	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHTJR_05005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AHTJR_05010	COG0602	queuosine metabolic process
AHTJR_05025	COG0583	DNA-binding transcription factor activity
AHTJR_05030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AHTJR_05035	COG4208	sulfate ABC transporter
AHTJR_05040	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AHTJR_05050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AHTJR_05055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AHTJR_05060	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AHTJR_05110	COG0481	GTPase activity
AHTJR_05125	COG0571	ribonuclease III activity
AHTJR_05130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AHTJR_05145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AHTJR_05190	COG0556	nucleotide-excision repair
AHTJR_05230	COG0582	viral genome integration into host DNA
AHTJR_05300	COG1840	ABC-type Fe3 transport system, periplasmic component
AHTJR_05305	COG3842	ATPase activity
AHTJR_05325	COG0583	DNA-binding transcription factor activity
AHTJR_05330	COG0596	Alpha beta hydrolase
AHTJR_05335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHTJR_05340	COG1773	rubredoxin
AHTJR_05350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AHTJR_05360	COG0175	sulfate reduction
AHTJR_05375	COG0222	ribosome binding
AHTJR_05380	COG1253	flavin adenine dinucleotide binding
AHTJR_05395	COG3015	lipoprotein NlpE involved in copper resistance
AHTJR_05410	COG0517	IMP dehydrogenase activity
AHTJR_05410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHTJR_05415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AHTJR_05425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AHTJR_05430	COG1137	ATPase activity
AHTJR_05480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AHTJR_05570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AHTJR_05595	COG0204	Acyl-transferase
AHTJR_05600	COG4783	chaperone-mediated protein folding
AHTJR_05620	COG1610	YqeY-like protein
AHTJR_05625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AHTJR_05645	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AHTJR_05710	COG1414	Transcriptional regulator
AHTJR_05715	COG2146	nitrite reductase [NAD(P)H] activity
AHTJR_05730	COG1028	Short-chain dehydrogenase reductase Sdr
AHTJR_05740	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHTJR_05745	COG2271	Major facilitator Superfamily
AHTJR_05760	COG1028	Short-chain dehydrogenase reductase Sdr
AHTJR_05775	COG0028	Belongs to the TPP enzyme family
AHTJR_05795	COG0482	sulfurtransferase activity
AHTJR_05810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AHTJR_05815	COG1686	Belongs to the peptidase S11 family
AHTJR_05835	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AHTJR_05845	COG0583	DNA-binding transcription factor activity
AHTJR_05850	COG1067	ATP-dependent peptidase activity
AHTJR_05870	COG0254	rRNA binding
AHTJR_05885	COG1509	lysine 2,3-aminomutase activity
AHTJR_05890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AHTJR_05895	COG1966	Carbon starvation protein
AHTJR_05900	COG2879	small protein
AHTJR_05905	COG0714	Associated with various cellular activities
AHTJR_05965	COG1741	Belongs to the pirin family
AHTJR_05980	COG1902	pentaerythritol trinitrate reductase activity
AHTJR_05980	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHTJR_06020	COG1570	exodeoxyribonuclease VII activity
AHTJR_06085	COG2271	Major facilitator Superfamily
AHTJR_06100	COG0642	Histidine kinase
AHTJR_06105	COG0745	RESPONSE REGULATOR receiver
AHTJR_06115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AHTJR_06120	COG3604	Transcriptional regulator
AHTJR_06145	COG1629	transport
AHTJR_06150	COG3501	Rhs element vgr protein
AHTJR_06155	COG3209	COG3209 Rhs family protein
AHTJR_06200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AHTJR_06210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHTJR_06215	COG1469	GTP cyclohydrolase I activity
AHTJR_06230	COG0523	cobalamin synthesis protein
AHTJR_06235	COG1414	Transcriptional regulator
AHTJR_06240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AHTJR_06245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AHTJR_06250	COG0183	Belongs to the thiolase family
AHTJR_06255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AHTJR_06260	COG0596	Alpha beta hydrolase
AHTJR_06265	COG2271	Major facilitator Superfamily
AHTJR_06275	COG3485	protocatechuate 3,4-dioxygenase
AHTJR_06280	COG3485	protocatechuate 3,4-dioxygenase
AHTJR_06285	COG0710	3-dehydroquinate dehydratase activity
AHTJR_06290	COG3420	alginic acid biosynthetic process
AHTJR_06295	COG3659	wide pore channel activity
AHTJR_06300	COG4993	Dehydrogenase
AHTJR_06310	COG2351	hydroxyisourate hydrolase activity
AHTJR_06315	COG2233	PERMEase
AHTJR_06325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHTJR_06330	COG2186	Transcriptional regulator
AHTJR_06335	COG4266	Belongs to the allantoicase family
AHTJR_06360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHTJR_06375	COG0583	DNA-binding transcription factor activity
AHTJR_06385	COG2188	Transcriptional regulator
AHTJR_06405	COG0010	Belongs to the arginase family
AHTJR_06410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AHTJR_06415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHTJR_06425	COG0243	molybdopterin cofactor binding
AHTJR_06430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AHTJR_06435	COG2837	iron assimilation
AHTJR_06445	COG1538	Outer membrane efflux protein
AHTJR_06450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHTJR_06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_06460	COG0745	RESPONSE REGULATOR receiver
AHTJR_06465	COG5002	protein histidine kinase activity
AHTJR_06470	COG3040	lipid binding
AHTJR_06490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AHTJR_06500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AHTJR_06505	COG0642	Histidine kinase
AHTJR_06525	COG1309	transcriptional regulator
AHTJR_06545	COG2072	flavoprotein involved in K transport
AHTJR_06550	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AHTJR_06555	COG1560	Kdo2-lipid A biosynthetic process
AHTJR_06560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AHTJR_06570	COG4770	biotin carboxylase activity
AHTJR_06575	COG0501	Belongs to the peptidase M48B family
AHTJR_06585	COG1765	OsmC-like protein
AHTJR_06665	COG0308	aminopeptidase N
AHTJR_06670	COG1760	l-serine dehydratase
AHTJR_06690	COG1714	RDD family
AHTJR_06700	COG0475	glutathione-regulated potassium exporter activity
AHTJR_06700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHTJR_06705	COG3135	benzoate transporter
AHTJR_06720	COG0583	DNA-binding transcription factor activity
AHTJR_06735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AHTJR_06765	COG0316	Belongs to the HesB IscA family
AHTJR_06770	COG0822	iron-sulfur transferase activity
AHTJR_06795	COG0776	regulation of translation
AHTJR_06800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHTJR_06815	COG2137	regulation of response to DNA damage stimulus
AHTJR_06825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AHTJR_06830	COG1011	Hydrolase
AHTJR_06835	COG1218	3'(2'),5'-bisphosphate nucleotidase
AHTJR_06855	COG0268	Binds directly to 16S ribosomal RNA
AHTJR_06860	COG0702	epimerase
AHTJR_06865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AHTJR_06875	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_06890	COG0183	Belongs to the thiolase family
AHTJR_06935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AHTJR_06940	COG0583	DNA-binding transcription factor activity
AHTJR_06945	COG0424	maF-like protein
AHTJR_07000	COG1286	toxin biosynthetic process
AHTJR_07045	COG3634	alkyl hydroperoxide reductase activity
AHTJR_07080	COG0436	Aminotransferase
AHTJR_07085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHTJR_07090	COG0386	Belongs to the glutathione peroxidase family
AHTJR_07100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_07115	COG1522	sequence-specific DNA binding
AHTJR_07125	COG0436	Aminotransferase
AHTJR_07140	COG1942	4-Oxalocrotonate Tautomerase
AHTJR_07150	COG1253	flavin adenine dinucleotide binding
AHTJR_07155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AHTJR_07165	COG0012	GTP binding
AHTJR_07170	COG2011	ABC-type metal ion transport system permease component
AHTJR_07175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHTJR_07180	COG1464	Belongs to the NlpA lipoprotein family
AHTJR_07210	COG2195	Cleaves the N-terminal amino acid of tripeptides
AHTJR_07220	COG3550	peptidyl-serine autophosphorylation
AHTJR_07265	COG2363	Small membrane protein
AHTJR_07285	COG0513	Belongs to the DEAD box helicase family
AHTJR_07295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AHTJR_07310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AHTJR_07320	COG1192	Involved in chromosome partitioning
AHTJR_07325	COG1475	DNA binding
AHTJR_07330	COG0811	peptide transport
AHTJR_07340	COG1132	(ABC) transporter
AHTJR_07345	COG1663	tetraacyldisaccharide 4'-kinase activity
AHTJR_07370	COG0084	hydrolase, TatD family'
AHTJR_07415	COG0590	tRNA wobble adenosine to inosine editing
AHTJR_07435	COG0776	regulation of translation
AHTJR_07450	COG2431	L-lysine efflux transmembrane transporter activity
AHTJR_07465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AHTJR_07470	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AHTJR_07520	COG0024	Methionine aminopeptidase
AHTJR_07525	COG0583	DNA-binding transcription factor activity
AHTJR_07535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AHTJR_07540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AHTJR_07545	COG0517	IMP dehydrogenase activity
AHTJR_07545	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AHTJR_07570	COG0552	protein localization to endoplasmic reticulum
AHTJR_07595	COG4890	Cyd operon protein YbgT
AHTJR_07600	COG1294	oxidase, subunit
AHTJR_07625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AHTJR_07645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AHTJR_07650	COG0569	domain protein
AHTJR_07655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AHTJR_07660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AHTJR_07695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AHTJR_07700	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AHTJR_07705	COG0542	response to heat
AHTJR_07715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHTJR_07720	COG2267	carboxylic ester hydrolase activity
AHTJR_07730	COG1902	pentaerythritol trinitrate reductase activity
AHTJR_07730	COG0446	pyridine nucleotide-disulphide oxidoreductase
AHTJR_07765	COG0148	phosphopyruvate hydratase activity
AHTJR_07770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AHTJR_07830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AHTJR_07840	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AHTJR_07855	COG1802	Transcriptional regulator
AHTJR_07865	COG2207	Transcriptional regulator
AHTJR_07870	COG1063	alcohol dehydrogenase
AHTJR_07880	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AHTJR_07925	COG1944	ATP diphosphatase activity
AHTJR_07945	COG1522	sequence-specific DNA binding
AHTJR_07960	COG0439	Biotin carboxylase
AHTJR_07965	COG0864	Transcriptional regulator
AHTJR_07970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHTJR_07980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHTJR_07985	COG1595	DNA-templated transcription, initiation
AHTJR_08045	COG0583	DNA-binding transcription factor activity
AHTJR_08060	COG1024	Enoyl-CoA hydratase
AHTJR_08065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AHTJR_08070	COG1960	acyl-CoA dehydrogenase activity
AHTJR_08075	COG1309	transcriptional regulator
AHTJR_08080	COG0318	PFAM AMP-dependent synthetase and ligase
AHTJR_08095	COG2814	Major facilitator Superfamily
AHTJR_08115	COG0583	DNA-binding transcription factor activity
AHTJR_08125	COG4774	siderophore transport
AHTJR_08160	COG0179	Fumarylacetoacetate (FAA) hydrolase
AHTJR_08175	COG2067	long-chain fatty acid transport protein
AHTJR_08205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHTJR_08290	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHTJR_08300	COG3706	GGDEF domain
AHTJR_08320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AHTJR_08340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AHTJR_08390	COG0537	adenosine 5'-monophosphoramidase activity
AHTJR_08420	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHTJR_08440	COG0730	response to heat
AHTJR_08445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AHTJR_08455	COG4771	TonB-dependent receptor
AHTJR_08475	COG0406	alpha-ribazole phosphatase activity
AHTJR_08480	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AHTJR_08495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AHTJR_08510	COG2223	nitrite transmembrane transporter activity
AHTJR_08555	COG1960	acyl-CoA dehydrogenase activity
AHTJR_08560	COG1960	acyl-CoA dehydrogenase activity
AHTJR_08565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AHTJR_08570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHTJR_08575	COG2207	Transcriptional regulator
AHTJR_08580	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHTJR_08615	COG0575	Belongs to the CDS family
AHTJR_08620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AHTJR_08630	COG0528	UMP kinase activity
AHTJR_08640	COG3852	Histidine kinase
AHTJR_08645	COG2204	response regulator
AHTJR_08650	COG1309	transcriptional regulator
AHTJR_08695	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AHTJR_08715	COG0697	spore germination
AHTJR_08720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AHTJR_08730	COG0303	'Molybdopterin
AHTJR_08735	COG0521	Mo-molybdopterin cofactor biosynthetic process
AHTJR_08735	COG0315	cyclic pyranopterin monophosphate synthase activity
AHTJR_08750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AHTJR_08755	COG0243	molybdopterin cofactor binding
AHTJR_08760	COG3048	D-serine ammonia-lyase activity
AHTJR_08770	COG0243	molybdopterin cofactor binding
AHTJR_08775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHTJR_08780	COG2146	nitrite reductase [NAD(P)H] activity
AHTJR_08780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AHTJR_08785	COG2223	nitrite transmembrane transporter activity
AHTJR_08795	COG1116	anion transmembrane transporter activity
AHTJR_08795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHTJR_08810	COG0439	Biotin carboxylase
AHTJR_08825	COG2814	Major facilitator Superfamily
AHTJR_08835	COG0069	glutamate synthase activity
AHTJR_08855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AHTJR_08880	COG3038	cytochrome b561
AHTJR_08885	COG1454	alcohol dehydrogenase
AHTJR_08890	COG0824	Thioesterase
AHTJR_08900	COG2850	peptidyl-arginine hydroxylation
AHTJR_08920	COG0640	Transcriptional regulator
AHTJR_08945	COG0668	transmembrane transport
AHTJR_08955	COG1132	(ABC) transporter
AHTJR_08975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AHTJR_08985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AHTJR_08985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AHTJR_08985	COG0506	proline dehydrogenase activity
AHTJR_08990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AHTJR_08995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AHTJR_09005	COG3698	Phosphodiester glycosidase
AHTJR_09020	COG3153	acetyltransferase
AHTJR_09025	COG2353	YceI-like domain
AHTJR_09040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AHTJR_09045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AHTJR_09060	COG3042	response to heat
AHTJR_09070	COG1278	Cold shock
AHTJR_09075	COG1278	Cold shock
AHTJR_09095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AHTJR_09095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AHTJR_09120	COG3539	Fimbrial protein
AHTJR_09175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AHTJR_09195	COG1960	acyl-CoA dehydrogenase activity
AHTJR_09230	COG3501	Rhs element vgr protein
AHTJR_09235	COG3139	Protein of unknown function (DUF1315)
AHTJR_09240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AHTJR_09255	COG0494	nUDIX hydrolase
AHTJR_09265	COG0642	Histidine kinase
AHTJR_09270	COG0745	RESPONSE REGULATOR receiver
AHTJR_09280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AHTJR_09285	COG1720	tRNA m6t6A37 methyltransferase activity
AHTJR_09320	COG0583	DNA-binding transcription factor activity
AHTJR_09325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AHTJR_09335	COG2814	Major facilitator Superfamily
AHTJR_09340	COG4607	ABC-type enterochelin transport system periplasmic component
AHTJR_09345	COG4604	ABC transporter, ATP-binding protein
AHTJR_09350	COG4605	iron ion homeostasis
AHTJR_09355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AHTJR_09365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AHTJR_09370	COG0471	metal ion transport
AHTJR_09395	COG0729	surface antigen
AHTJR_09420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AHTJR_09455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AHTJR_09550	COG1131	(ABC) transporter
AHTJR_09555	COG0842	Transport permease protein
AHTJR_09570	COG0772	Belongs to the SEDS family
AHTJR_09575	COG2951	lytic endotransglycosylase activity
AHTJR_09600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AHTJR_09615	COG1643	Atp-dependent helicase
AHTJR_09620	COG0450	alkyl hydroperoxide reductase
AHTJR_09630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHTJR_09650	COG3634	alkyl hydroperoxide reductase activity
AHTJR_09670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AHTJR_09685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AHTJR_09695	COG0519	Catalyzes the synthesis of GMP from XMP
AHTJR_09695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHTJR_09700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHTJR_09710	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AHTJR_09720	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHTJR_09730	COG0697	spore germination
AHTJR_09735	COG1923	regulation of RNA biosynthetic process
AHTJR_09745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AHTJR_09750	COG0802	atpase or kinase
AHTJR_09770	COG1187	pseudouridine synthase activity
AHTJR_09780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AHTJR_09785	COG5001	Diguanylate cyclase
AHTJR_09785	COG3300	MHYT domain
AHTJR_09805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AHTJR_09810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AHTJR_09815	COG1845	cytochrome c oxidase, subunit III
AHTJR_09820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AHTJR_09845	COG2249	NAD(P)H dehydrogenase (quinone) activity
AHTJR_09850	COG1733	regulation of RNA biosynthetic process
AHTJR_09855	COG0305	Participates in initiation and elongation during chromosome replication
AHTJR_09860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AHTJR_09875	COG1305	Transglutaminase-like
AHTJR_09885	COG2308	Evidence 4 Homologs of previously reported genes of
AHTJR_09895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AHTJR_09930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AHTJR_09940	COG0527	aspartate kinase activity
AHTJR_09950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AHTJR_09960	COG3038	cytochrome b561
AHTJR_09965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AHTJR_09970	COG2252	PERMEase
AHTJR_10025	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AHTJR_10030	COG0138	bifunctional purine biosynthesis protein purh
AHTJR_10035	COG0151	Belongs to the GarS family
AHTJR_10040	COG1464	Belongs to the NlpA lipoprotein family
AHTJR_10045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AHTJR_10050	COG2011	ABC-type metal ion transport system permease component
AHTJR_10085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AHTJR_10090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AHTJR_10095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AHTJR_10120	COG0052	Belongs to the universal ribosomal protein uS2 family
AHTJR_10125	COG0024	Methionine aminopeptidase
AHTJR_10135	COG2223	nitrite transmembrane transporter activity
AHTJR_10145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AHTJR_10150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AHTJR_10155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AHTJR_10190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AHTJR_10195	COG3161	chorismate lyase activity
AHTJR_10210	COG0512	Glutamine amidotransferase of anthranilate synthase
AHTJR_10220	COG3217	Mosc domain protein beta barrel domain protein
AHTJR_10220	COG0633	Ferredoxin
AHTJR_10245	COG0302	gtp cyclohydrolase
AHTJR_10265	COG3739	integral membrane protein
AHTJR_10280	COG5001	Diguanylate cyclase
AHTJR_10280	COG4251	negative regulation of phosphorylation
AHTJR_10280	COG3706	GGDEF domain
AHTJR_10280	COG2203	Gaf domain
AHTJR_10290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AHTJR_10305	COG4172	Belongs to the ABC transporter superfamily
AHTJR_10310	COG4239	(ABC) transporter, permease
AHTJR_10315	COG4174	ABC transporter (Permease)
AHTJR_10320	COG4166	transmembrane transport
AHTJR_10325	COG1388	LysM domain
AHTJR_10325	COG0741	lytic transglycosylase activity
AHTJR_10325	COG1388	LysM domain
AHTJR_10325	COG0741	lytic transglycosylase activity
AHTJR_10330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AHTJR_10340	COG2816	NAD+ diphosphatase activity
AHTJR_10370	COG0583	DNA-binding transcription factor activity
AHTJR_10375	COG1279	arginine transmembrane transporter activity
AHTJR_10395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHTJR_10400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHTJR_10405	COG0006	proline dipeptidase activity
AHTJR_10435	COG2217	Heavy metal translocating P-type atpase
AHTJR_10460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AHTJR_10475	COG3384	dioxygenase
AHTJR_10485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AHTJR_10515	COG3501	Rhs element vgr protein
AHTJR_10520	COG2878	Part of a membrane complex involved in electron transport
AHTJR_10525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AHTJR_10550	COG0768	penicillin binding
AHTJR_10555	COG0742	ribosomal rna small subunit methyltransferase
AHTJR_10580	COG0616	signal peptide processing
AHTJR_10585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AHTJR_10595	COG0573	inorganic phosphate transmembrane transporter activity
AHTJR_10610	COG0076	glutamate decarboxylase activity
AHTJR_10615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AHTJR_10625	COG1309	transcriptional regulator
AHTJR_10655	COG0783	Belongs to the Dps family
AHTJR_10665	COG0564	pseudouridine synthase activity
AHTJR_10680	COG0352	thiamine-phosphate diphosphorylase activity
AHTJR_10710	COG0612	Peptidase, M16
AHTJR_10715	COG0384	phenazine biosynthesis protein PhzF
AHTJR_10750	COG1686	Belongs to the peptidase S11 family
AHTJR_10755	COG1252	NADH dehydrogenase
AHTJR_10765	COG0415	Belongs to the DNA photolyase family
AHTJR_10785	COG1271	oxidase subunit
AHTJR_10790	COG1294	oxidase, subunit
AHTJR_10810	COG0457	Tetratricopeptide repeat
AHTJR_10810	COG0705	Rhomboid family
AHTJR_10820	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AHTJR_10825	COG4181	ATPase activity
AHTJR_10835	COG0456	acetyltransferase
AHTJR_10845	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_10860	COG4771	TonB-dependent receptor
AHTJR_10880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AHTJR_10910	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AHTJR_10915	COG1597	lipid kinase activity
AHTJR_10920	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AHTJR_10940	COG2831	hemolysin activation secretion protein
AHTJR_10960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AHTJR_10970	COG2388	GCN5-related N-acetyl-transferase
AHTJR_11015	COG4681	YaeQ
AHTJR_11020	COG0523	cobalamin synthesis protein
AHTJR_11030	COG1607	acyl-coa hydrolase
AHTJR_11050	COG2814	Major facilitator Superfamily
AHTJR_11055	COG1024	Enoyl-CoA hydratase
AHTJR_11060	COG1012	belongs to the aldehyde dehydrogenase family
AHTJR_11070	COG1960	acyl-CoA dehydrogenase activity
AHTJR_11090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHTJR_11095	COG1414	Transcriptional regulator
AHTJR_11110	COG0281	malic enzyme
AHTJR_11115	COG0833	amino acid
AHTJR_11130	COG1012	belongs to the aldehyde dehydrogenase family
AHTJR_11140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AHTJR_11145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AHTJR_11155	COG1960	acyl-CoA dehydrogenase activity
AHTJR_11160	COG1454	alcohol dehydrogenase
AHTJR_11210	COG0582	viral genome integration into host DNA
AHTJR_11235	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_11260	COG2814	Major facilitator Superfamily
AHTJR_11265	COG1566	PFAM secretion protein HlyD family protein
AHTJR_11270	COG2050	protein possibly involved in aromatic compounds catabolism
AHTJR_11280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AHTJR_11285	COG1090	epimerase
AHTJR_11305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHTJR_11310	COG0420	3'-5' exonuclease activity
AHTJR_11340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AHTJR_11345	COG2914	Belongs to the UPF0125 (RnfH) family
AHTJR_11360	COG0121	glutamine amidotransferase
AHTJR_11380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHTJR_11385	COG0756	dUTP diphosphatase activity
AHTJR_11390	COG0210	DNA helicase
AHTJR_11395	COG2885	chlorophyll binding
AHTJR_11400	COG0204	Acyl-transferase
AHTJR_11410	COG0850	regulation of cytokinetic process
AHTJR_11415	COG2894	cell division
AHTJR_11420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AHTJR_11430	COG1280	lysine exporter protein (LysE YggA)
AHTJR_11435	COG1674	ftsk spoiiie
AHTJR_11440	COG0492	ferredoxin-NADP+ reductase activity
AHTJR_11445	COG0500	methyltransferase
AHTJR_11460	COG0456	acetyltransferase
AHTJR_11490	COG0049	tRNA binding
AHTJR_11525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHTJR_11525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AHTJR_11550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AHTJR_11580	COG0564	pseudouridine synthase activity
AHTJR_11590	COG0358	DNA primase activity
AHTJR_11605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AHTJR_11635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AHTJR_11670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AHTJR_11680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AHTJR_11680	COG0352	thiamine-phosphate diphosphorylase activity
AHTJR_11680	COG0351	phosphomethylpyrimidine kinase
AHTJR_11695	COG1652	LysM domain
AHTJR_11720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AHTJR_11725	COG1399	metal-binding, possibly nucleic acid-binding protein
AHTJR_11730	COG3101	peptidyl-lysine hydroxylation
AHTJR_11735	COG0009	L-threonylcarbamoyladenylate synthase
AHTJR_11750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AHTJR_11755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AHTJR_11775	COG0601	transmembrane transport
AHTJR_11785	COG0747	negative chemotaxis
AHTJR_11830	COG4106	trans-aconitate 2-methyltransferase activity
AHTJR_11845	COG2226	methyltransferase
AHTJR_11845	COG0596	Alpha beta hydrolase
AHTJR_11845	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AHTJR_11855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AHTJR_11870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AHTJR_11880	COG1196	nuclear chromosome segregation
AHTJR_11890	COG0730	response to heat
AHTJR_11910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AHTJR_11990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHTJR_11995	COG0489	protein tyrosine kinase activity
AHTJR_12015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHTJR_12015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AHTJR_12030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AHTJR_12050	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AHTJR_12055	COG2081	HI0933 family
AHTJR_12060	COG0668	transmembrane transport
AHTJR_12080	COG0583	DNA-binding transcription factor activity
AHTJR_12100	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHTJR_12105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AHTJR_12110	COG0713	ATP synthesis coupled electron transport
AHTJR_12120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHTJR_12135	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AHTJR_12145	COG0649	NAD binding
AHTJR_12145	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHTJR_12155	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AHTJR_12180	COG2205	protein histidine kinase activity
AHTJR_12185	COG0745	RESPONSE REGULATOR receiver
AHTJR_12200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AHTJR_12215	COG1131	(ABC) transporter
AHTJR_12225	COG1113	amino acid transport
AHTJR_12235	COG0625	glutathione transferase activity
AHTJR_12260	COG2814	Major facilitator Superfamily
AHTJR_12270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHTJR_12275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHTJR_12280	COG1309	transcriptional regulator
AHTJR_12300	COG1063	alcohol dehydrogenase
AHTJR_12345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AHTJR_12350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AHTJR_12355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AHTJR_12360	COG2076	Multidrug Resistance protein
AHTJR_12380	COG2132	Multicopper oxidase
AHTJR_12390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AHTJR_12415	COG1968	undecaprenyl-diphosphatase activity
AHTJR_12420	COG1214	PFAM Peptidase M22, glycoprotease
AHTJR_12430	COG0494	nUDIX hydrolase
AHTJR_12480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AHTJR_12490	COG1595	DNA-templated transcription, initiation
AHTJR_12495	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AHTJR_12500	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AHTJR_12560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AHTJR_12570	COG1764	response to oxidative stress
AHTJR_12595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHTJR_12595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AHTJR_12610	COG0037	tRNA processing
AHTJR_12620	COG0248	Ppx GppA phosphatase
AHTJR_12645	COG0072	phenylalanine-tRNA ligase activity
AHTJR_12670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AHTJR_12680	COG1238	metal cluster binding
AHTJR_12695	COG0625	glutathione transferase activity
AHTJR_12715	COG0318	PFAM AMP-dependent synthetase and ligase
AHTJR_12720	COG3028	Belongs to the UPF0307 family
AHTJR_12745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AHTJR_12750	COG0617	tRNA 3'-terminal CCA addition
AHTJR_12755	COG1555	photosystem II stabilization
AHTJR_12760	COG3956	TIGRFAM MazG family protein
AHTJR_12775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AHTJR_12795	COG2205	protein histidine kinase activity
AHTJR_12795	COG5002	protein histidine kinase activity
AHTJR_12795	COG0784	Response regulator, receiver
AHTJR_12805	COG2084	Dehydrogenase
AHTJR_12810	COG3622	Belongs to the hyi family
AHTJR_12825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AHTJR_12830	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AHTJR_12835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AHTJR_12840	COG0789	Transcriptional regulator
AHTJR_12850	COG2814	Major facilitator Superfamily
AHTJR_12855	COG5285	phytanoyl-CoA dioxygenase
AHTJR_12865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AHTJR_12870	COG0456	acetyltransferase
AHTJR_12880	COG0431	NADPH-dependent FMN reductase
AHTJR_12885	COG0798	PFAM Bile acid sodium symporter
AHTJR_12895	COG0640	Transcriptional regulator
AHTJR_12910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AHTJR_12920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AHTJR_12935	COG0084	hydrolase, TatD family'
AHTJR_12950	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AHTJR_12975	COG3501	Rhs element vgr protein
AHTJR_13040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AHTJR_13045	COG0440	acetolactate synthase activity
AHTJR_13050	COG0028	Belongs to the TPP enzyme family
AHTJR_13070	COG1466	dna polymerase III delta subunit
AHTJR_13075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_13080	COG1136	(ABC) transporter
AHTJR_13080	COG0577	efflux transmembrane transporter activity
AHTJR_13085	COG1538	Outer membrane efflux protein
AHTJR_13105	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AHTJR_13110	COG1162	GTPase activity
AHTJR_13120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AHTJR_13155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AHTJR_13165	COG3781	membrane
AHTJR_13205	COG1666	GTP binding
AHTJR_13220	COG1956	GAF domain-containing protein
AHTJR_13225	COG1607	acyl-coa hydrolase
AHTJR_13240	COG3453	Protein conserved in bacteria
AHTJR_13240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHTJR_13280	COG1183	phosphatidylcholine synthase activity
AHTJR_13285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AHTJR_13315	COG0741	lytic transglycosylase activity
AHTJR_13315	COG1196	nuclear chromosome segregation
AHTJR_13315	COG0739	heme binding
AHTJR_13325	COG1702	phosphate starvation-inducible protein PhoH
AHTJR_13415	COG0788	formyltetrahydrofolate deformylase activity
AHTJR_13430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AHTJR_13435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AHTJR_13440	COG4651	solute:proton antiporter activity
AHTJR_13440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AHTJR_13460	COG0210	DNA helicase
AHTJR_13505	COG1560	Kdo2-lipid A biosynthetic process
AHTJR_13555	COG0473	3-isopropylmalate dehydrogenase activity
AHTJR_13590	COG0494	nUDIX hydrolase
AHTJR_13605	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AHTJR_13610	COG3011	Protein conserved in bacteria
AHTJR_13625	COG0625	glutathione transferase activity
AHTJR_13640	COG0564	pseudouridine synthase activity
AHTJR_13650	COG1530	ribonuclease E activity
AHTJR_13670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AHTJR_13680	COG0534	Mate efflux family protein
AHTJR_13685	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AHTJR_13710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHTJR_13735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AHTJR_13775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AHTJR_13790	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AHTJR_13800	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AHTJR_13800	COG0644	oxidoreductase
AHTJR_13805	COG0425	Belongs to the sulfur carrier protein TusA family
AHTJR_13810	COG4535	Mg2 and Co2 transporter CorC
AHTJR_13815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AHTJR_13835	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AHTJR_13845	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AHTJR_13860	COG0789	Transcriptional regulator
AHTJR_13865	COG0598	Magnesium transport protein CorA
AHTJR_13870	COG1185	polyribonucleotide nucleotidyltransferase activity
AHTJR_13875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AHTJR_13885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AHTJR_13890	COG1074	ATP-dependent DNA helicase activity
AHTJR_13895	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AHTJR_13920	COG2226	methyltransferase
AHTJR_13935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHTJR_13945	COG1116	anion transmembrane transporter activity
AHTJR_13950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AHTJR_13960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AHTJR_13975	COG2111	Na H antiporter
AHTJR_13975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AHTJR_13980	COG1006	Multisubunit Na H antiporter MnhC subunit
AHTJR_13985	COG0651	ATP synthesis coupled electron transport
AHTJR_13995	COG2212	antiporter activity
AHTJR_14005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AHTJR_14015	COG0195	Participates in both transcription termination and antitermination
AHTJR_14065	COG0237	dephospho-CoA kinase activity
AHTJR_14080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AHTJR_14090	COG0497	DNA recombination
AHTJR_14100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AHTJR_14130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AHTJR_14170	COG1132	(ABC) transporter
AHTJR_14180	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AHTJR_14200	COG0326	Molecular chaperone. Has ATPase activity
AHTJR_14210	COG2056	Na+-H+ antiporter family
AHTJR_14265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AHTJR_14275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AHTJR_14285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AHTJR_14315	COG0546	phosphoglycolate phosphatase activity
AHTJR_14365	COG0181	hydroxymethylbilane synthase activity
AHTJR_14375	COG3275	phosphorelay sensor kinase activity
AHTJR_14400	COG0494	nUDIX hydrolase
AHTJR_14410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AHTJR_14415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AHTJR_14420	COG0772	Belongs to the SEDS family
AHTJR_14445	COG4974	Belongs to the 'phage' integrase family
AHTJR_14450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHTJR_14460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AHTJR_14465	COG1686	Belongs to the peptidase S11 family
AHTJR_14470	COG2197	response regulator
AHTJR_14485	COG0793	Belongs to the peptidase S41A family
AHTJR_14490	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AHTJR_14495	COG0795	lipopolysaccharide-transporting ATPase activity
AHTJR_14500	COG0795	lipopolysaccharide-transporting ATPase activity
AHTJR_14535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHTJR_14535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AHTJR_14540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AHTJR_14545	COG0004	ammonium transporteR
AHTJR_14550	COG0347	Belongs to the P(II) protein family
AHTJR_14625	COG1538	Outer membrane efflux protein
AHTJR_14635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AHTJR_14640	COG1230	cation diffusion facilitator family transporter
AHTJR_14650	COG0640	Transcriptional regulator
AHTJR_14660	COG0789	Transcriptional regulator
AHTJR_14690	COG2814	Major facilitator Superfamily
AHTJR_14730	COG0633	Ferredoxin
AHTJR_14780	COG0606	chelatase, subunit chli
AHTJR_14815	COG0318	PFAM AMP-dependent synthetase and ligase
AHTJR_14825	COG2860	membrane
AHTJR_14835	COG1253	flavin adenine dinucleotide binding
AHTJR_14855	COG2814	Major facilitator Superfamily
AHTJR_14865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHTJR_14890	COG2814	Major facilitator Superfamily
AHTJR_14900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AHTJR_14950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AHTJR_14965	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AHTJR_14970	COG3162	membrane
AHTJR_14975	COG2205	protein histidine kinase activity
AHTJR_14985	COG4771	TonB-dependent receptor
AHTJR_15000	COG1652	LysM domain
AHTJR_15005	COG0758	DNA mediated transformation
AHTJR_15020	COG1309	transcriptional regulator
AHTJR_15025	COG2814	Major facilitator Superfamily
AHTJR_15035	COG0386	Belongs to the glutathione peroxidase family
AHTJR_15060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AHTJR_15070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AHTJR_15110	COG1121	(ABC) transporter
AHTJR_15115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AHTJR_15120	COG1280	lysine exporter protein (LysE YggA)
AHTJR_15125	COG2837	iron assimilation
AHTJR_15160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AHTJR_15165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AHTJR_15180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AHTJR_15185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AHTJR_15185	COG0519	Catalyzes the synthesis of GMP from XMP
AHTJR_15190	COG4399	Belongs to the UPF0754 family
AHTJR_15200	COG2259	Doxx family
AHTJR_15205	COG0586	Pfam SNARE associated Golgi protein
AHTJR_15220	COG1192	Involved in chromosome partitioning
AHTJR_15230	COG0271	Belongs to the BolA IbaG family
AHTJR_15265	COG3756	Protein conserved in bacteria
AHTJR_15300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AHTJR_15375	COG0477	Major facilitator Superfamily
AHTJR_15380	COG1024	Enoyl-CoA hydratase
AHTJR_15385	COG1024	Enoyl-CoA hydratase
AHTJR_15390	COG1960	acyl-CoA dehydrogenase activity
AHTJR_15395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AHTJR_15415	COG1113	amino acid transport
AHTJR_15420	COG0251	oxidation-reduction process
AHTJR_15435	COG1522	sequence-specific DNA binding
AHTJR_15460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AHTJR_15495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AHTJR_15510	COG1802	Transcriptional regulator
AHTJR_15515	COG1448	Aminotransferase
AHTJR_15520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHTJR_15525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AHTJR_15540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AHTJR_15550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AHTJR_15560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AHTJR_15585	COG2244	polysaccharide biosynthetic process
AHTJR_15590	COG2089	acid synthase
AHTJR_15605	COG1083	cytidylyl-transferase
AHTJR_15610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AHTJR_15615	COG1086	Polysaccharide biosynthesis protein
AHTJR_15640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AHTJR_15645	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AHTJR_15680	COG3023	N-Acetylmuramoyl-L-alanine amidase
AHTJR_15715	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_15735	COG0546	phosphoglycolate phosphatase activity
AHTJR_15740	COG1028	Short-chain dehydrogenase reductase Sdr
AHTJR_15750	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AHTJR_15750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AHTJR_15755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHTJR_15760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AHTJR_15765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AHTJR_15770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AHTJR_15775	COG1116	anion transmembrane transporter activity
AHTJR_15780	COG1309	transcriptional regulator
AHTJR_15790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AHTJR_15800	COG0196	riboflavin kinase activity
AHTJR_15805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AHTJR_15815	COG1047	Peptidyl-prolyl cis-trans
AHTJR_15855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AHTJR_15880	COG0583	DNA-binding transcription factor activity
AHTJR_15890	COG0443	Heat shock 70 kDa protein
AHTJR_15895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AHTJR_15925	COG2951	lytic endotransglycosylase activity
AHTJR_15930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AHTJR_15950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AHTJR_15975	COG1960	acyl-CoA dehydrogenase activity
AHTJR_15985	COG0861	Integral membrane protein TerC family
AHTJR_15990	COG0402	S-adenosylhomocysteine deaminase activity
AHTJR_16005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AHTJR_16015	COG0706	membrane insertase activity
AHTJR_16030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AHTJR_16085	COG3316	Transposase and inactivated derivatives
AHTJR_16100	COG3316	Transposase and inactivated derivatives
AHTJR_16110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AHTJR_16125	COG4783	chaperone-mediated protein folding
AHTJR_16360	COG1475	DNA binding
AHTJR_16520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AHTJR_16585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AHTJR_16635	COG0625	glutathione transferase activity
AHTJR_16640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHTJR_16700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AHTJR_16850	COG2826	transposase and inactivated derivatives, IS30 family
AHTJR_17015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AHTJR_17065	COG1525	nuclease
AHTJR_17075	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AHTJR_17120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AHTJR_17265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHTJR_17270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AHTJR_17290	COG0183	Belongs to the thiolase family
AHTJR_17295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AHTJR_17300	COG3706	GGDEF domain
AHTJR_17350	COG0860	N-Acetylmuramoyl-L-alanine amidase
AHTJR_17385	COG2801	Transposase and inactivated derivatives
AHTJR_17395	COG0745	RESPONSE REGULATOR receiver
AHTJR_17400	COG5002	protein histidine kinase activity
AHTJR_17410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AHTJR_17435	COG2801	Transposase and inactivated derivatives
AHTJR_17455	COG3657	addiction module killer protein
AHTJR_17460	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AHTJR_17490	COG3316	Transposase and inactivated derivatives
AHTJR_17495	COG0583	DNA-binding transcription factor activity
AHTJR_17510	COG3316	Transposase and inactivated derivatives
AHTJR_17515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AHTJR_17540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism