locus-tag	class	description
FK538_00045	COG3328	transposase activity
FK538_00085	COG3077	Addiction module antitoxin, RelB DinJ family
FK538_00090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FK538_00095	COG0592	DNA-directed DNA polymerase activity
FK538_00105	COG0187	DNA topoisomerase II activity
FK538_00130	COG0488	(ABC) transporter
FK538_00155	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FK538_00160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FK538_00185	COG0737	Belongs to the 5'-nucleotidase family
FK538_00215	COG2814	Major facilitator Superfamily
FK538_00225	COG1012	belongs to the aldehyde dehydrogenase family
FK538_00230	COG0733	neurotransmitter:sodium symporter activity
FK538_00240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FK538_00260	COG0129	dihydroxy-acid dehydratase activity
FK538_00275	COG2233	PERMEase
FK538_00285	COG1309	transcriptional regulator
FK538_00290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK538_00345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FK538_00360	COG0438	transferase activity, transferring glycosyl groups
FK538_00365	COG1216	Glycosyl transferase, family 2
FK538_00365	COG1442	glycosyl transferase family 8
FK538_00375	COG0438	transferase activity, transferring glycosyl groups
FK538_00385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FK538_00400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FK538_00415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FK538_00420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK538_00450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FK538_00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FK538_00495	COG0271	Belongs to the BolA IbaG family
FK538_00505	COG1192	Involved in chromosome partitioning
FK538_00520	COG0586	Pfam SNARE associated Golgi protein
FK538_00525	COG2259	Doxx family
FK538_00530	COG0519	Catalyzes the synthesis of GMP from XMP
FK538_00530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK538_00570	COG0281	malic enzyme
FK538_00575	COG3501	Rhs element vgr protein
FK538_00580	COG3179	chitinase
FK538_00600	COG2837	iron assimilation
FK538_00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK538_00615	COG1121	(ABC) transporter
FK538_00665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FK538_00690	COG0386	Belongs to the glutathione peroxidase family
FK538_00695	COG0697	spore germination
FK538_00710	COG0758	DNA mediated transformation
FK538_00760	COG2814	Major facilitator Superfamily
FK538_00785	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FK538_00800	COG2814	Major facilitator Superfamily
FK538_00820	COG1253	flavin adenine dinucleotide binding
FK538_00830	COG2860	membrane
FK538_00835	COG0477	Major facilitator Superfamily
FK538_00845	COG0318	PFAM AMP-dependent synthetase and ligase
FK538_00860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FK538_00885	COG0347	Belongs to the P(II) protein family
FK538_00890	COG0004	ammonium transporteR
FK538_00900	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK538_00900	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK538_00915	COG0586	Pfam SNARE associated Golgi protein
FK538_00940	COG0795	lipopolysaccharide-transporting ATPase activity
FK538_00945	COG0795	lipopolysaccharide-transporting ATPase activity
FK538_00950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FK538_00955	COG0793	Belongs to the peptidase S41A family
FK538_00970	COG2197	response regulator
FK538_00980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FK538_00995	COG4974	Belongs to the 'phage' integrase family
FK538_01020	COG0772	Belongs to the SEDS family
FK538_01030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FK538_01035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FK538_01040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK538_01045	COG0494	nUDIX hydrolase
FK538_01080	COG3275	phosphorelay sensor kinase activity
FK538_01090	COG0181	hydroxymethylbilane synthase activity
FK538_01110	COG0824	Thioesterase
FK538_01195	COG0081	regulation of translation
FK538_01210	COG0085	RNA polymerase activity
FK538_01215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FK538_01235	COG2056	Na+-H+ antiporter family
FK538_01250	COG0326	Molecular chaperone. Has ATPase activity
FK538_01275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FK538_01285	COG2233	PERMEase
FK538_01295	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK538_01295	COG1024	Enoyl-CoA hydratase
FK538_01325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FK538_01330	COG1132	(ABC) transporter
FK538_01345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FK538_01355	COG0497	DNA recombination
FK538_01360	COG3123	guanosine phosphorylase activity
FK538_01365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK538_01375	COG0237	dephospho-CoA kinase activity
FK538_01425	COG0779	Required for maturation of 30S ribosomal subunits
FK538_01430	COG0195	Participates in both transcription termination and antitermination
FK538_01440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FK538_01450	COG2212	antiporter activity
FK538_01460	COG0651	ATP synthesis coupled electron transport
FK538_01465	COG1006	Multisubunit Na H antiporter MnhC subunit
FK538_01470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK538_01470	COG2111	Na H antiporter
FK538_01485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FK538_01495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FK538_01525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FK538_01530	COG1074	ATP-dependent DNA helicase activity
FK538_01535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK538_01540	COG0675	Transposase, IS605 OrfB family
FK538_01545	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FK538_01560	COG2841	Protein conserved in bacteria
FK538_01565	COG0789	Transcriptional regulator
FK538_01575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FK538_01585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FK538_01605	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FK538_01610	COG4535	Mg2 and Co2 transporter CorC
FK538_01615	COG0425	Belongs to the sulfur carrier protein TusA family
FK538_01620	COG3501	Rhs element vgr protein
FK538_01700	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FK538_01700	COG0644	oxidoreductase
FK538_01710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FK538_01725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK538_01735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FK538_01745	COG0493	'glutamate synthase
FK538_01745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK538_01755	COG2226	methyltransferase
FK538_01770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FK538_01800	COG0751	glycine-tRNA ligase activity
FK538_01810	COG0617	tRNA 3'-terminal CCA addition
FK538_01810	COG0517	IMP dehydrogenase activity
FK538_01810	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FK538_01815	COG1983	PspC domain protein
FK538_01840	COG0318	PFAM AMP-dependent synthetase and ligase
FK538_01845	COG1530	ribonuclease E activity
FK538_01860	COG0546	phosphoglycolate phosphatase activity
FK538_01865	COG3971	2-oxopent-4-enoate hydratase activity
FK538_01870	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FK538_01895	COG0583	DNA-binding transcription factor activity
FK538_01900	COG4638	Rieske (2fe-2S)
FK538_01915	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_01920	COG3384	dioxygenase
FK538_01925	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK538_01940	COG0753	catalase activity
FK538_01950	COG1960	acyl-CoA dehydrogenase activity
FK538_01970	COG0494	nUDIX hydrolase
FK538_01985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FK538_02000	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FK538_02015	COG0473	3-isopropylmalate dehydrogenase activity
FK538_02070	COG1560	Kdo2-lipid A biosynthetic process
FK538_02080	COG2900	Belongs to the SlyX family
FK538_02110	COG1929	Belongs to the glycerate kinase type-1 family
FK538_02120	COG0210	DNA helicase
FK538_02125	COG0724	RNA recognition motif
FK538_02140	COG4651	solute:proton antiporter activity
FK538_02140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK538_02165	COG0788	formyltetrahydrofolate deformylase activity
FK538_02195	COG1295	ribonuclease BN
FK538_02240	COG1702	phosphate starvation-inducible protein PhoH
FK538_02250	COG0741	lytic transglycosylase activity
FK538_02250	COG0739	heme binding
FK538_02250	COG1196	nuclear chromosome segregation
FK538_02265	COG3385	transposase activity
FK538_02295	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FK538_02300	COG1183	phosphatidylcholine synthase activity
FK538_02365	COG1607	acyl-coa hydrolase
FK538_02375	COG1666	GTP binding
FK538_02395	COG2350	Protein conserved in bacteria
FK538_02405	COG0613	PHP domain protein
FK538_02410	COG3781	membrane
FK538_02420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FK538_02430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK538_02440	COG1162	GTPase activity
FK538_02445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FK538_02465	COG3209	COG3209 Rhs family protein
FK538_02535	COG1136	(ABC) transporter
FK538_02535	COG0577	efflux transmembrane transporter activity
FK538_02540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK538_02565	COG0028	Belongs to the TPP enzyme family
FK538_02570	COG0440	acetolactate synthase activity
FK538_02610	COG2975	iron-sulfur cluster assembly
FK538_02640	COG0124	histidyl-tRNA synthetase
FK538_02650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK538_02665	COG3956	TIGRFAM MazG family protein
FK538_02670	COG1555	photosystem II stabilization
FK538_02675	COG0617	tRNA 3'-terminal CCA addition
FK538_02680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FK538_02695	COG1660	Displays ATPase and GTPase activities
FK538_02705	COG3028	Belongs to the UPF0307 family
FK538_02710	COG0318	PFAM AMP-dependent synthetase and ligase
FK538_02725	COG0625	glutathione transferase activity
FK538_02730	COG1238	metal cluster binding
FK538_02765	COG0072	phenylalanine-tRNA ligase activity
FK538_02790	COG0248	Ppx GppA phosphatase
FK538_02800	COG0037	tRNA processing
FK538_02845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK538_02900	COG2969	positive regulation of protein catabolic process
FK538_02905	COG0625	glutathione transferase activity
FK538_02910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FK538_02920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FK538_02925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FK538_02930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FK538_02960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FK538_02970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK538_02975	COG1408	metallophosphoesterase
FK538_02985	COG0477	Major facilitator Superfamily
FK538_02990	COG1272	protein, Hemolysin III
FK538_03015	COG1024	Enoyl-CoA hydratase
FK538_03015	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK538_03020	COG0183	Belongs to the thiolase family
FK538_03025	COG2207	Transcriptional regulator
FK538_03035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK538_03050	COG0183	Belongs to the thiolase family
FK538_03070	COG0833	amino acid
FK538_03080	COG2233	PERMEase
FK538_03090	COG1970	mechanosensitive ion channel activity
FK538_03105	COG1877	trehalose-phosphatase activity
FK538_03110	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FK538_03120	COG0363	glucosamine-6-phosphate deaminase activity
FK538_03150	COG0354	folic acid binding
FK538_03185	COG0346	lactoylglutathione lyase activity
FK538_03190	COG0564	pseudouridine synthase activity
FK538_03205	COG3189	MarR family transcriptional regulator
FK538_03210	COG2824	Alkylphosphonate utilization operon protein PhnA
FK538_03270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FK538_03290	COG0730	response to heat
FK538_03300	COG1196	nuclear chromosome segregation
FK538_03305	COG3115	cell septum assembly
FK538_03310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FK538_03315	COG2193	ferroxidase activity
FK538_03320	COG0596	Alpha beta hydrolase
FK538_03320	COG2226	methyltransferase
FK538_03320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK538_03335	COG4106	trans-aconitate 2-methyltransferase activity
FK538_03350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FK538_03355	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FK538_03365	COG0009	L-threonylcarbamoyladenylate synthase
FK538_03370	COG3101	peptidyl-lysine hydroxylation
FK538_03375	COG1399	metal-binding, possibly nucleic acid-binding protein
FK538_03390	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_03400	COG1652	LysM domain
FK538_03405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK538_03420	COG0745	RESPONSE REGULATOR receiver
FK538_03425	COG2205	protein histidine kinase activity
FK538_03430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK538_03445	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK538_03460	COG3338	carbonate dehydratase activity
FK538_03465	COG1126	abc transporter atp-binding protein
FK538_03470	COG0765	amino acid transport
FK538_03475	COG0765	amino acid transport
FK538_03490	COG2323	membrane
FK538_03505	COG2852	Protein conserved in bacteria
FK538_03530	COG0525	valine-tRNA ligase activity
FK538_03545	COG0393	Putative heavy-metal-binding
FK538_03550	COG0393	Putative heavy-metal-binding
FK538_03555	COG1538	Outer membrane efflux protein
FK538_03565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK538_03570	COG0671	phosphoesterase, PA-phosphatase related
FK538_03595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FK538_03605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FK538_03610	COG1648	precorrin-2 dehydrogenase activity
FK538_03610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FK538_03615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FK538_03620	COG0531	amino acid
FK538_03640	COG0321	lipoyl(octanoyl) transferase activity
FK538_03680	COG0586	Pfam SNARE associated Golgi protein
FK538_03720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK538_03750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FK538_03765	COG0358	DNA primase activity
FK538_03775	COG0564	pseudouridine synthase activity
FK538_03790	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FK538_03800	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK538_03830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FK538_03830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK538_03845	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FK538_03855	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_03875	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FK538_03880	COG1053	succinate dehydrogenase
FK538_03885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FK538_03900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK538_03910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FK538_03920	COG1649	PFAM Uncharacterised BCR, COG1649
FK538_03920	COG0726	polysaccharide deacetylase
FK538_03925	COG1215	transferase activity, transferring glycosyl groups
FK538_03935	COG2268	Band 7 protein
FK538_03950	COG2354	Protein conserved in bacteria
FK538_03955	COG2321	neutral zinc metallopeptidase
FK538_03965	COG0589	response to stress
FK538_03970	COG0110	maltose O-acetyltransferase activity
FK538_03975	COG0251	oxidation-reduction process
FK538_03980	COG1309	transcriptional regulator
FK538_03995	COG0505	Belongs to the CarA family
FK538_04010	COG1534	Rna-binding protein
FK538_04020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK538_04030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FK538_04065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FK538_04085	COG1597	lipid kinase activity
FK538_04120	COG2239	Acts as a magnesium transporter
FK538_04130	COG0501	Belongs to the peptidase M48B family
FK538_04135	COG0741	lytic transglycosylase activity
FK538_04135	COG1196	nuclear chromosome segregation
FK538_04135	COG0739	heme binding
FK538_04140	COG0037	tRNA processing
FK538_04150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FK538_04155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK538_04170	COG1840	ABC-type Fe3 transport system, periplasmic component
FK538_04175	COG3842	ATPase activity
FK538_04180	COG1741	Belongs to the pirin family
FK538_04190	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FK538_04195	COG3739	integral membrane protein
FK538_04210	COG3706	GGDEF domain
FK538_04240	COG0512	Glutamine amidotransferase of anthranilate synthase
FK538_04245	COG0174	glutamine synthetase
FK538_04255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FK538_04265	COG0583	DNA-binding transcription factor activity
FK538_04300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FK538_04305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FK538_04330	COG1115	amino acid carrier protein
FK538_04335	COG1113	amino acid transport
FK538_04345	COG0019	diaminopimelate decarboxylase activity
FK538_04360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FK538_04370	COG1522	sequence-specific DNA binding
FK538_04375	COG1280	lysine exporter protein (LysE YggA)
FK538_04415	COG1671	Belongs to the UPF0178 family
FK538_04430	COG4591	ABC-type transport system involved in lipoprotein release permease component
FK538_04435	COG1136	(ABC) transporter
FK538_04440	COG2333	competence protein COMEC
FK538_04440	COG0658	competence protein
FK538_04460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FK538_04465	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FK538_04470	COG0628	permease
FK538_04475	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FK538_04505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK538_04520	COG3385	transposase activity
FK538_04530	COG0823	Involved in the tonB-independent uptake of proteins
FK538_04550	COG0824	Thioesterase
FK538_04555	COG1473	amidohydrolase
FK538_04570	COG2255	four-way junction helicase activity
FK538_04590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FK538_04590	COG0047	phosphoribosylformylglycinamidine synthase activity
FK538_04605	COG0778	Nitroreductase
FK538_04610	COG1024	Enoyl-CoA hydratase
FK538_04615	COG1051	belongs to the nudix hydrolase family
FK538_04615	COG1056	cytidyltransferase-related domain
FK538_04620	COG2353	YceI-like domain
FK538_04625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK538_04635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FK538_04640	COG0602	queuosine metabolic process
FK538_04660	COG0583	DNA-binding transcription factor activity
FK538_04665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FK538_04670	COG4208	sulfate ABC transporter
FK538_04685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FK538_04695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FK538_04710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK538_04720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK538_04735	COG0681	Belongs to the peptidase S26 family
FK538_04745	COG0571	ribonuclease III activity
FK538_04750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FK538_04760	COG1381	Involved in DNA repair and RecF pathway recombination
FK538_04765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FK538_04790	COG0436	Aminotransferase
FK538_04810	COG0556	nucleotide-excision repair
FK538_04840	COG0702	epimerase
FK538_04845	COG1733	regulation of RNA biosynthetic process
FK538_04850	COG2814	Major facilitator Superfamily
FK538_04860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FK538_04870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK538_04875	COG0076	glutamate decarboxylase activity
FK538_04885	COG0573	inorganic phosphate transmembrane transporter activity
FK538_04895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FK538_04900	COG0616	signal peptide processing
FK538_04940	COG1929	Belongs to the glycerate kinase type-1 family
FK538_04945	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK538_04950	COG1686	Belongs to the peptidase S11 family
FK538_04965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FK538_04975	COG0583	DNA-binding transcription factor activity
FK538_04980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK538_04985	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FK538_04990	COG1067	ATP-dependent peptidase activity
FK538_05025	COG1509	lysine 2,3-aminomutase activity
FK538_05030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FK538_05035	COG1966	Carbon starvation protein
FK538_05040	COG2879	small protein
FK538_05045	COG0714	Associated with various cellular activities
FK538_05075	COG2252	PERMEase
FK538_05080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FK538_05090	COG1215	transferase activity, transferring glycosyl groups
FK538_05100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FK538_05110	COG0527	aspartate kinase activity
FK538_05120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FK538_05135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FK538_05140	COG0501	Belongs to the peptidase M48B family
FK538_05155	COG0667	Aldo Keto reductase
FK538_05165	COG1765	OsmC-like protein
FK538_05185	COG0540	Belongs to the ATCase OTCase family
FK538_05200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK538_05215	COG4770	biotin carboxylase activity
FK538_05220	COG1024	Enoyl-CoA hydratase
FK538_05225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FK538_05230	COG1960	acyl-CoA dehydrogenase activity
FK538_05235	COG1309	transcriptional regulator
FK538_05240	COG0318	PFAM AMP-dependent synthetase and ligase
FK538_05260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FK538_05270	COG0659	secondary active sulfate transmembrane transporter activity
FK538_05280	COG3385	transposase activity
FK538_05295	COG2363	Small membrane protein
FK538_05315	COG0513	Belongs to the DEAD box helicase family
FK538_05380	COG4783	chaperone-mediated protein folding
FK538_05395	COG1610	YqeY-like protein
FK538_05425	COG0515	serine threonine protein kinase
FK538_05425	COG2815	serine threonine protein kinase
FK538_05465	COG2755	lipolytic protein G-D-S-L family
FK538_05465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FK538_05470	COG0436	Aminotransferase
FK538_05475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FK538_05480	COG0386	Belongs to the glutathione peroxidase family
FK538_05490	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FK538_05505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK538_05515	COG0012	GTP binding
FK538_05555	COG0204	Acyl-transferase
FK538_05565	COG0582	viral genome integration into host DNA
FK538_05590	COG3586	endonuclease activity
FK538_05625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK538_05630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FK538_05635	COG0022	dehydrogenase e1 component
FK538_05640	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK538_05645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK538_05680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FK538_05685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FK538_05695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FK538_05710	COG2986	histidine ammonia-lyase
FK538_05750	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_05755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FK538_05790	COG0579	oxidoreductase
FK538_05855	COG5002	protein histidine kinase activity
FK538_05855	COG5001	Diguanylate cyclase
FK538_05870	COG0783	Belongs to the Dps family
FK538_05875	COG2814	Major facilitator Superfamily
FK538_05880	COG1012	belongs to the aldehyde dehydrogenase family
FK538_05880	COG2030	dehydratase
FK538_05885	COG3396	Phenylacetate-CoA oxygenase
FK538_05890	COG3460	Phenylacetate-CoA oxygenase
FK538_05895	COG3396	Phenylacetate-CoA oxygenase
FK538_05900	COG2151	metal-sulfur cluster biosynthetic enzyme
FK538_05905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK538_05910	COG1024	Enoyl-CoA hydratase
FK538_05915	COG1024	Enoyl-CoA hydratase
FK538_05920	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK538_05925	COG0183	Belongs to the thiolase family
FK538_05930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FK538_05935	COG3327	negative regulation of DNA-templated transcription, initiation
FK538_05945	COG0318	PFAM AMP-dependent synthetase and ligase
FK538_05965	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FK538_05970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FK538_05970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FK538_05975	COG1254	Belongs to the acylphosphatase family
FK538_06015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FK538_06020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FK538_06030	COG2353	YceI-like domain
FK538_06035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK538_06035	COG0519	Catalyzes the synthesis of GMP from XMP
FK538_06055	COG1454	alcohol dehydrogenase
FK538_06065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK538_06070	COG0583	DNA-binding transcription factor activity
FK538_06080	COG2707	UPF0756 membrane protein
FK538_06105	COG0802	atpase or kinase
FK538_06110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FK538_06120	COG1923	regulation of RNA biosynthetic process
FK538_06125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK538_06135	COG3178	'Phosphotransferase
FK538_06140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FK538_06150	COG1192	Involved in chromosome partitioning
FK538_06155	COG1475	DNA binding
FK538_06160	COG0811	peptide transport
FK538_06170	COG1132	(ABC) transporter
FK538_06175	COG1663	tetraacyldisaccharide 4'-kinase activity
FK538_06195	COG0084	hydrolase, TatD family'
FK538_06230	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FK538_06260	COG0776	regulation of translation
FK538_06270	COG0284	orotidine-5'-phosphate decarboxylase activity
FK538_06275	COG2431	L-lysine efflux transmembrane transporter activity
FK538_06290	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FK538_06295	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FK538_06315	COG1253	flavin adenine dinucleotide binding
FK538_06345	COG0583	DNA-binding transcription factor activity
FK538_06355	COG2204	response regulator
FK538_06360	COG3852	Histidine kinase
FK538_06375	COG0233	cytoplasmic translational termination
FK538_06380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FK538_06385	COG0575	Belongs to the CDS family
FK538_06420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK538_06450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK538_06455	COG0730	response to heat
FK538_06460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK538_06465	COG2207	Transcriptional regulator
FK538_06470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK538_06480	COG1960	acyl-CoA dehydrogenase activity
FK538_06485	COG1960	acyl-CoA dehydrogenase activity
FK538_06520	COG4890	Cyd operon protein YbgT
FK538_06525	COG1294	oxidase, subunit
FK538_06540	COG1585	Membrane protein implicated in regulation of membrane protease activity
FK538_06550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK538_06570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FK538_06575	COG0569	domain protein
FK538_06585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FK538_06605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FK538_06610	COG0542	response to heat
FK538_06625	COG0477	Major facilitator Superfamily
FK538_06645	COG0372	Belongs to the citrate synthase family
FK538_06655	COG1546	Belongs to the CinA family
FK538_06655	COG1058	Belongs to the CinA family
FK538_06720	COG2814	Major facilitator Superfamily
FK538_06735	COG0439	Biotin carboxylase
FK538_06740	COG0511	ligase activity, forming carbon-carbon bonds
FK538_06775	COG0596	Alpha beta hydrolase
FK538_06930	COG1309	transcriptional regulator
FK538_06950	COG0730	response to heat
FK538_06955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK538_06960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FK538_06970	COG2885	chlorophyll binding
FK538_06995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FK538_07005	COG0745	RESPONSE REGULATOR receiver
FK538_07025	COG1012	belongs to the aldehyde dehydrogenase family
FK538_07030	COG1309	transcriptional regulator
FK538_07035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK538_07070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK538_07085	COG0515	serine threonine protein kinase
FK538_07090	COG2116	formate transmembrane transporter activity
FK538_07095	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FK538_07105	COG2223	nitrite transmembrane transporter activity
FK538_07115	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_07145	COG2814	Major facilitator Superfamily
FK538_07150	COG0583	DNA-binding transcription factor activity
FK538_07155	COG4948	Mandelate Racemase Muconate Lactonizing
FK538_07160	COG4829	muconolactone delta-isomerase
FK538_07170	COG4638	Rieske (2fe-2S)
FK538_07175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FK538_07180	COG0543	2 iron, 2 sulfur cluster binding
FK538_07180	COG0633	Ferredoxin
FK538_07185	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_07190	COG3135	benzoate transporter
FK538_07195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK538_07200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK538_07205	COG0183	Belongs to the thiolase family
FK538_07210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK538_07230	COG0583	DNA-binding transcription factor activity
FK538_07235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FK538_07240	COG4149	molybdate abc transporter
FK538_07250	COG0303	'Molybdopterin
FK538_07255	COG0315	cyclic pyranopterin monophosphate synthase activity
FK538_07255	COG0521	Mo-molybdopterin cofactor biosynthetic process
FK538_07270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FK538_07280	COG0243	molybdopterin cofactor binding
FK538_07285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK538_07290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK538_07295	COG2223	nitrite transmembrane transporter activity
FK538_07305	COG1116	anion transmembrane transporter activity
FK538_07305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK538_07310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK538_07315	COG2937	Belongs to the GPAT DAPAT family
FK538_07320	COG0640	Transcriptional regulator
FK538_07340	COG3122	Protein conserved in bacteria
FK538_07345	COG0668	transmembrane transport
FK538_07355	COG1132	(ABC) transporter
FK538_07375	COG2814	Major facilitator Superfamily
FK538_07385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK538_07395	COG1113	amino acid transport
FK538_07410	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FK538_07415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK538_07465	COG1525	nuclease
FK538_07480	COG1271	oxidase subunit
FK538_07490	COG2814	Major facilitator Superfamily
FK538_07495	COG2207	Transcriptional regulator
FK538_07495	COG1917	Cupin 2, conserved barrel domain protein
FK538_07500	COG1960	acyl-CoA dehydrogenase activity
FK538_07510	COG1629	transport
FK538_07525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FK538_07530	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FK538_07550	COG0583	DNA-binding transcription factor activity
FK538_07560	COG1346	cytolysis
FK538_07570	COG1283	sodium-dependent phosphate transmembrane transporter activity
FK538_07580	COG0693	protein deglycase activity
FK538_07625	COG0552	protein localization to endoplasmic reticulum
FK538_07630	COG0612	Peptidase, M16
FK538_07660	COG0617	tRNA 3'-terminal CCA addition
FK538_07660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FK538_07660	COG0517	IMP dehydrogenase activity
FK538_07665	COG0133	tryptophan synthase activity
FK538_07675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK538_07695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FK538_07750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK538_07780	COG0822	iron-sulfur transferase activity
FK538_07785	COG0316	Belongs to the HesB IscA family
FK538_07815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK538_07830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK538_07835	COG0702	epimerase
FK538_07865	COG1011	Hydrolase
FK538_07870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FK538_07880	COG2137	regulation of response to DNA damage stimulus
FK538_07895	COG0772	Belongs to the SEDS family
FK538_07910	COG0148	phosphopyruvate hydratase activity
FK538_07930	COG0583	DNA-binding transcription factor activity
FK538_07940	COG2814	Major facilitator Superfamily
FK538_07955	COG1902	pentaerythritol trinitrate reductase activity
FK538_07955	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK538_07970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FK538_07975	COG2814	Major facilitator Superfamily
FK538_07980	COG1960	acyl-CoA dehydrogenase activity
FK538_07985	COG0583	DNA-binding transcription factor activity
FK538_07990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FK538_07995	COG1027	Aspartate ammonia-lyase
FK538_08000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK538_08010	COG0506	proline dehydrogenase activity
FK538_08010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK538_08010	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK538_08030	COG3698	Phosphodiester glycosidase
FK538_08070	COG0697	spore germination
FK538_08095	COG0424	maF-like protein
FK538_08100	COG2850	peptidyl-arginine hydroxylation
FK538_08105	COG4585	Histidine kinase
FK538_08115	COG0069	glutamate synthase activity
FK538_08135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FK538_08140	COG1454	alcohol dehydrogenase
FK538_08145	COG0824	Thioesterase
FK538_08165	COG2030	dehydratase
FK538_08175	COG0183	Belongs to the thiolase family
FK538_08190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FK538_08200	COG3135	benzoate transporter
FK538_08210	COG0589	response to stress
FK538_08215	COG0589	response to stress
FK538_08225	COG0308	aminopeptidase N
FK538_08255	COG0786	glutamate:sodium symporter activity
FK538_08305	COG0477	Major facilitator Superfamily
FK538_08320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FK538_08330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FK538_08340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK538_08345	COG1960	acyl-CoA dehydrogenase activity
FK538_08365	COG3781	membrane
FK538_08375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FK538_08390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK538_08415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FK538_08420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FK538_08425	COG1845	cytochrome c oxidase, subunit III
FK538_08430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FK538_08440	COG0360	Binds together with S18 to 16S ribosomal RNA
FK538_08445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FK538_08460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FK538_08475	COG1305	Transglutaminase-like
FK538_08485	COG2308	Evidence 4 Homologs of previously reported genes of
FK538_08525	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FK538_08530	COG0138	bifunctional purine biosynthesis protein purh
FK538_08550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK538_08555	COG2011	ABC-type metal ion transport system permease component
FK538_08590	COG1454	alcohol dehydrogenase
FK538_08600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FK538_08610	COG4122	O-methyltransferase activity
FK538_08635	COG2274	protein secretion by the type I secretion system
FK538_08645	COG1137	ATPase activity
FK538_08650	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FK538_08660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FK538_08665	COG0517	IMP dehydrogenase activity
FK538_08665	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FK538_08690	COG1643	Atp-dependent helicase
FK538_08720	COG3634	alkyl hydroperoxide reductase activity
FK538_08730	COG3385	transposase activity
FK538_08755	COG2070	2-Nitropropane dioxygenase
FK538_08770	COG1278	Cold shock
FK538_08805	COG1309	transcriptional regulator
FK538_08810	COG0596	Alpha beta hydrolase
FK538_08845	COG2433	Pfam Transposase IS66
FK538_08870	COG0352	thiamine-phosphate diphosphorylase activity
FK538_08905	COG0612	Peptidase, M16
FK538_08915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK538_08925	COG0739	heme binding
FK538_08935	COG1187	pseudouridine synthase activity
FK538_08950	COG1686	Belongs to the peptidase S11 family
FK538_08955	COG1252	NADH dehydrogenase
FK538_08960	COG1047	Peptidyl-prolyl cis-trans
FK538_08985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FK538_08990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FK538_09000	COG0693	protein deglycase activity
FK538_09005	COG1960	acyl-CoA dehydrogenase activity
FK538_09010	COG1301	dicarboxylic acid transport
FK538_09020	COG3139	Protein of unknown function (DUF1315)
FK538_09025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FK538_09030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FK538_09050	COG0642	Histidine kinase
FK538_09055	COG0745	RESPONSE REGULATOR receiver
FK538_09065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FK538_09080	COG2963	transposase activity
FK538_09090	COG4372	Transposase
FK538_09100	COG1720	tRNA m6t6A37 methyltransferase activity
FK538_09125	COG0789	Transcriptional regulator
FK538_09130	COG0431	NADPH-dependent FMN reductase
FK538_09135	COG0798	PFAM Bile acid sodium symporter
FK538_09145	COG0640	Transcriptional regulator
FK538_09160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK538_09165	COG3634	alkyl hydroperoxide reductase activity
FK538_09185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK538_09245	COG1131	(ABC) transporter
FK538_09250	COG0842	Transport permease protein
FK538_09265	COG2951	lytic endotransglycosylase activity
FK538_09290	COG0052	Belongs to the universal ribosomal protein uS2 family
FK538_09310	COG2175	clavaminate synthase activity
FK538_09320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK538_09350	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FK538_09355	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FK538_09360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK538_09380	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FK538_09410	COG2871	sodium ion transport
FK538_09425	COG0582	viral genome integration into host DNA
FK538_09510	COG4372	Transposase
FK538_09570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FK538_09620	COG2801	Transposase and inactivated derivatives
FK538_09655	COG2184	nucleotidyltransferase activity
FK538_09705	COG1902	pentaerythritol trinitrate reductase activity
FK538_09705	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK538_09720	COG4251	negative regulation of phosphorylation
FK538_09720	COG5001	Diguanylate cyclase
FK538_09720	COG3706	GGDEF domain
FK538_09720	COG2203	Gaf domain
FK538_09725	COG0418	dihydroorotase activity
FK538_09730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK538_09750	COG0833	amino acid
FK538_09780	COG4172	Belongs to the ABC transporter superfamily
FK538_09785	COG4239	(ABC) transporter, permease
FK538_09790	COG4174	ABC transporter (Permease)
FK538_09795	COG4166	transmembrane transport
FK538_09800	COG1388	LysM domain
FK538_09800	COG0741	lytic transglycosylase activity
FK538_09805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK538_09815	COG2816	NAD+ diphosphatase activity
FK538_09850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK538_09855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK538_09865	COG0006	proline dipeptidase activity
FK538_09870	COG3079	Belongs to the UPF0149 family
FK538_09905	COG0277	FAD linked oxidase domain protein
FK538_09915	COG2186	Transcriptional regulator
FK538_09950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FK538_09960	COG2234	aminopeptidase activity
FK538_09970	COG3384	dioxygenase
FK538_09980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK538_09985	COG2878	Part of a membrane complex involved in electron transport
FK538_09990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FK538_10015	COG0768	penicillin binding
FK538_10020	COG0742	ribosomal rna small subunit methyltransferase
FK538_10035	COG0830	nickel cation binding
FK538_10050	COG0804	urea catabolic process
FK538_10070	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_10085	COG3015	lipoprotein NlpE involved in copper resistance
FK538_10105	COG1253	flavin adenine dinucleotide binding
FK538_10120	COG0604	alcohol dehydrogenase
FK538_10120	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_10120	COG3321	synthase
FK538_10125	COG3118	belongs to the thioredoxin family
FK538_10165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FK538_10170	COG1773	rubredoxin
FK538_10175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK538_10185	COG0583	DNA-binding transcription factor activity
FK538_10195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FK538_10205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FK538_10210	COG4181	ATPase activity
FK538_10235	COG4771	TonB-dependent receptor
FK538_10260	COG0306	phosphate transporter
FK538_10275	COG0477	Major facilitator Superfamily
FK538_10305	COG2199	diguanylate cyclase activity
FK538_10305	COG2203	Gaf domain
FK538_10315	COG4681	YaeQ
FK538_10320	COG0523	cobalamin synthesis protein
FK538_10350	COG0583	DNA-binding transcription factor activity
FK538_10355	COG2814	Major facilitator Superfamily
FK538_10365	COG1607	acyl-coa hydrolase
FK538_10375	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK538_10380	COG2059	Chromate
FK538_10385	COG1115	amino acid carrier protein
FK538_10390	COG0786	glutamate:sodium symporter activity
FK538_10405	COG2814	Major facilitator Superfamily
FK538_10410	COG1289	transmembrane transporter activity
FK538_10420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FK538_10475	COG1376	ErfK ybiS ycfS ynhG family protein
FK538_10480	COG2832	Protein of unknown function (DUF454)
FK538_10490	COG5510	response to toxic substance
FK538_10505	COG0784	Response regulator, receiver
FK538_10505	COG2198	Histidine kinase
FK538_10505	COG0643	Histidine kinase
FK538_10510	COG0840	transmembrane signaling receptor activity
FK538_10545	COG0442	prolyl-tRNA aminoacylation
FK538_10580	COG2358	TRAP transporter, solute receptor (TAXI family
FK538_10595	COG0489	protein tyrosine kinase activity
FK538_10600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK538_10600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK538_10635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FK538_10650	COG2081	HI0933 family
FK538_10660	COG0668	transmembrane transport
FK538_10685	COG0583	DNA-binding transcription factor activity
FK538_10690	COG1278	Cold shock
FK538_10695	COG1278	Cold shock
FK538_10710	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK538_10715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK538_10720	COG0713	ATP synthesis coupled electron transport
FK538_10725	COG0839	Belongs to the complex I subunit 6 family
FK538_10730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK538_10735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FK538_10745	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FK538_10765	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK538_10775	COG0142	geranyltranstransferase activity
FK538_10780	COG2828	Protein conserved in bacteria
FK538_10785	COG1113	amino acid transport
FK538_10805	COG0625	glutathione transferase activity
FK538_10845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK538_10850	COG1530	ribonuclease E activity
FK538_10855	COG0424	maF-like protein
FK538_10860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FK538_10865	COG1792	Involved in formation and maintenance of cell shape
FK538_10870	COG1077	Cell shape determining protein MreB Mrl
FK538_10875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK538_10885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK538_10905	COG0697	spore germination
FK538_10920	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FK538_10935	COG1215	transferase activity, transferring glycosyl groups
FK538_10940	COG1649	PFAM Uncharacterised BCR, COG1649
FK538_10940	COG0726	polysaccharide deacetylase
FK538_10965	COG3177	Filamentation induced by cAMP protein fic
FK538_11015	COG1802	Transcriptional regulator
FK538_11030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FK538_11035	COG3385	transposase activity
FK538_11040	COG2050	protein possibly involved in aromatic compounds catabolism
FK538_11060	COG0420	3'-5' exonuclease activity
FK538_11090	COG0735	belongs to the Fur family
FK538_11095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK538_11100	COG2914	Belongs to the UPF0125 (RnfH) family
FK538_11115	COG0121	glutamine amidotransferase
FK538_11130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK538_11140	COG0210	DNA helicase
FK538_11145	COG2885	chlorophyll binding
FK538_11150	COG0204	Acyl-transferase
FK538_11160	COG0850	regulation of cytokinetic process
FK538_11165	COG2894	cell division
FK538_11180	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FK538_11180	COG1674	ftsk spoiiie
FK538_11185	COG0492	ferredoxin-NADP+ reductase activity
FK538_11190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FK538_11200	COG0456	acetyltransferase
FK538_11225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FK538_11245	COG1113	amino acid transport
FK538_11250	COG0251	oxidation-reduction process
FK538_11275	COG0352	thiamine-phosphate diphosphorylase activity
FK538_11275	COG0351	phosphomethylpyrimidine kinase
FK538_11275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK538_11290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK538_11295	COG2076	Multidrug Resistance protein
FK538_11305	COG2132	Multicopper oxidase
FK538_11315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FK538_11330	COG4269	membrane
FK538_11350	COG1968	undecaprenyl-diphosphatase activity
FK538_11355	COG1214	PFAM Peptidase M22, glycoprotease
FK538_11365	COG0494	nUDIX hydrolase
FK538_11415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FK538_11420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FK538_11480	COG2199	diguanylate cyclase activity
FK538_11510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FK538_11515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FK538_11530	COG0450	alkyl hydroperoxide reductase
FK538_11545	COG0285	dihydrofolate synthase activity
FK538_11550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FK538_11595	COG4206	TonB-dependent receptor
FK538_11600	COG2096	Adenosyltransferase
FK538_11620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FK538_11625	COG2315	Protein conserved in bacteria
FK538_11635	COG0745	RESPONSE REGULATOR receiver
FK538_11640	COG2205	protein histidine kinase activity
FK538_11650	COG1960	acyl-CoA dehydrogenase activity
FK538_11655	COG1960	acyl-CoA dehydrogenase activity
FK538_11660	COG3223	Belongs to the PsiE family
FK538_11690	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FK538_11705	COG1215	transferase activity, transferring glycosyl groups
FK538_11740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FK538_11745	COG5002	protein histidine kinase activity
FK538_11760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FK538_11770	COG1704	LemA family
FK538_11785	COG1862	Preprotein translocase
FK538_11805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK538_11820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK538_11825	COG0784	Response regulator, receiver
FK538_11825	COG2205	protein histidine kinase activity
FK538_11825	COG5002	protein histidine kinase activity
FK538_11830	COG1024	Enoyl-CoA hydratase
FK538_11840	COG3622	Belongs to the hyi family
FK538_11865	COG0697	spore germination
FK538_11870	COG2814	Major facilitator Superfamily
FK538_11900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK538_11905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FK538_11910	COG0084	hydrolase, TatD family'
FK538_11925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FK538_11945	COG0793	Belongs to the peptidase S41A family
FK538_11975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FK538_11980	COG0857	belongs to the CobB CobQ family
FK538_11980	COG0280	phosphate acetyltransferase
FK538_12000	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK538_12000	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK538_12015	COG0740	serine-type endopeptidase activity
FK538_12025	COG4771	TonB-dependent receptor
FK538_12030	COG4774	siderophore transport
FK538_12035	COG3128	pkhd-type hydroxylase
FK538_12045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FK538_12050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK538_12055	COG2813	Specifically methylates the guanine in position
FK538_12055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK538_12115	COG3040	lipid binding
FK538_12145	COG0179	Fumarylacetoacetate (FAA) hydrolase
FK538_12180	COG0557	exoribonuclease II activity
FK538_12185	COG0339	signal peptide processing
FK538_12190	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FK538_12225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FK538_12230	COG1960	acyl-CoA dehydrogenase activity
FK538_12235	COG2072	flavoprotein involved in K transport
FK538_12245	COG0202	RNA polymerase activity
FK538_12250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FK538_12285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FK538_12295	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FK538_12300	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FK538_12335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FK538_12365	COG0088	Forms part of the polypeptide exit tunnel
FK538_12390	COG0433	COG0433 Predicted ATPase
FK538_12400	COG1959	2 iron, 2 sulfur cluster binding
FK538_12420	COG1301	dicarboxylic acid transport
FK538_12425	COG1946	Acyl-CoA thioesterase
FK538_12430	COG2937	Belongs to the GPAT DAPAT family
FK538_12440	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FK538_12445	COG1040	competence protein
FK538_12460	COG0598	Magnesium transport protein CorA
FK538_12465	COG3385	transposase activity
FK538_12475	COG2854	intermembrane phospholipid transfer
FK538_12480	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FK538_12485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FK538_12490	COG1127	ABC transporter
FK538_12515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK538_12535	COG1960	acyl-CoA dehydrogenase activity
FK538_12540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK538_12550	COG0534	Mate efflux family protein
FK538_12555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FK538_12560	COG0254	rRNA binding
FK538_12565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FK538_12585	COG2226	methyltransferase
FK538_12595	COG0675	Transposase, IS605 OrfB family
FK538_12605	COG1192	Involved in chromosome partitioning
FK538_12610	COG0628	permease
FK538_12620	COG2814	Major facilitator Superfamily
FK538_12635	COG0277	FAD linked oxidase domain protein
FK538_12640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FK538_12665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FK538_12670	COG5380	lipid catabolic process
FK538_12675	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FK538_12700	COG0335	large ribosomal subunit rRNA binding
FK538_12710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FK538_12715	COG0228	four-way junction DNA binding
FK538_12760	COG0194	GDP metabolic process
FK538_12765	COG1758	RNA polymerase activity
FK538_12770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK538_12790	COG3307	-O-antigen
FK538_12800	COG4969	Belongs to the N-Me-Phe pilin family
FK538_12810	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FK538_12815	COG1704	LemA family
FK538_12825	COG0493	'glutamate synthase
FK538_12830	COG0067	glutamate synthase
FK538_12830	COG0069	glutamate synthase activity
FK538_12830	COG0070	glutamate synthase
FK538_12880	COG2226	methyltransferase
FK538_12890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FK538_12895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FK538_12910	COG0275	rRNA processing
FK538_12920	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FK538_12930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FK538_12950	COG0488	(ABC) transporter
FK538_12960	COG4221	oxidoreductase activity
FK538_12975	COG0745	RESPONSE REGULATOR receiver
FK538_12980	COG2205	protein histidine kinase activity
FK538_12985	COG0427	acetyl-CoA hydrolase
FK538_13015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FK538_13050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FK538_13090	COG3158	transport of potassium into the cell
FK538_13115	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FK538_13130	COG0629	single-stranded DNA binding
FK538_13135	COG2814	Major facilitator Superfamily
FK538_13145	COG0351	phosphomethylpyrimidine kinase
FK538_13145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK538_13145	COG0352	thiamine-phosphate diphosphorylase activity
FK538_13150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FK538_13155	COG3706	GGDEF domain
FK538_13165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK538_13185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK538_13190	COG3162	membrane
FK538_13195	COG2205	protein histidine kinase activity
FK538_13195	COG0784	Response regulator, receiver
FK538_13210	COG0431	NADPH-dependent FMN reductase
FK538_13225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK538_13230	COG0668	transmembrane transport
FK538_13235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK538_13240	COG1519	Transferase
FK538_13245	COG1902	pentaerythritol trinitrate reductase activity
FK538_13250	COG0640	Transcriptional regulator
FK538_13270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FK538_13295	COG0426	domain, Protein
FK538_13295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK538_13300	COG2119	membrane
FK538_13330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FK538_13340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FK538_13350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FK538_13355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FK538_13360	COG0189	ligase activity
FK538_13380	COG0708	Exodeoxyribonuclease III
FK538_13385	COG1393	Belongs to the ArsC family
FK538_13400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FK538_13405	COG3706	GGDEF domain
FK538_13410	COG0625	glutathione transferase activity
FK538_13450	COG1247	-acetyltransferase
FK538_13455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK538_13460	COG4266	Belongs to the allantoicase family
FK538_13465	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FK538_13475	COG0471	metal ion transport
FK538_13515	COG3150	esterase
FK538_13525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FK538_13530	COG2918	glutathione biosynthetic process
FK538_13545	COG2733	membrane
FK538_13550	COG0436	Aminotransferase
FK538_13555	COG0534	Mate efflux family protein
FK538_13600	COG0753	catalase activity
FK538_13620	COG3830	Belongs to the UPF0237 family
FK538_13620	COG0560	Phosphoserine phosphatase
FK538_13635	COG0385	Bile acid
FK538_13640	COG1335	isochorismatase
FK538_13645	COG2814	Major facilitator Superfamily
FK538_13650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK538_13660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FK538_13665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FK538_13670	COG2983	Belongs to the UPF0260 family
FK538_13675	COG5487	UPF0391 membrane protein
FK538_13690	COG1194	a g-specific adenine glycosylase
FK538_13695	COG0739	heme binding
FK538_13705	COG2818	Glycosylase
FK538_13710	COG1064	alcohol dehydrogenase
FK538_13730	COG3023	N-Acetylmuramoyl-L-alanine amidase
FK538_13740	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FK538_13745	COG1309	transcriptional regulator
FK538_13755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FK538_13760	COG0546	phosphoglycolate phosphatase activity
FK538_13765	COG1028	Short-chain dehydrogenase reductase Sdr
FK538_13790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK538_13795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK538_13800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK538_13805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK538_13810	COG1116	anion transmembrane transporter activity
FK538_13825	COG1309	transcriptional regulator
FK538_13835	COG0196	riboflavin kinase activity
FK538_13840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FK538_13845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FK538_13850	COG1047	Peptidyl-prolyl cis-trans
FK538_13860	COG2133	pyrroloquinoline quinone binding
FK538_13865	COG2814	Major facilitator Superfamily
FK538_13895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FK538_13940	COG2951	lytic endotransglycosylase activity
FK538_13945	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FK538_13965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FK538_13985	COG2388	GCN5-related N-acetyl-transferase
FK538_13995	COG0861	Integral membrane protein TerC family
FK538_14000	COG3385	transposase activity
FK538_14005	COG0402	S-adenosylhomocysteine deaminase activity
FK538_14020	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK538_14025	COG1230	cation diffusion facilitator family transporter
FK538_14050	COG0706	membrane insertase activity
FK538_14055	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FK538_14060	COG0594	ribonuclease P activity
FK538_14115	COG1373	ATPase (AAA superfamily
FK538_14160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FK538_14170	COG2132	Multicopper oxidase
FK538_14185	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FK538_14225	COG2862	Uncharacterized protein family, UPF0114
FK538_14235	COG0659	secondary active sulfate transmembrane transporter activity
FK538_14350	COG2801	Transposase and inactivated derivatives
FK538_14380	COG4974	Belongs to the 'phage' integrase family
FK538_14410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK538_14490	COG1660	Displays ATPase and GTPase activities
FK538_14515	COG0659	secondary active sulfate transmembrane transporter activity
FK538_14520	COG0589	response to stress
FK538_14525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FK538_14535	COG1475	DNA binding
FK538_14540	COG1192	Involved in chromosome partitioning