locus-tag	class	description
MOW12_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MOW12_00010	COG0592	DNA-directed DNA polymerase activity
MOW12_00020	COG0187	DNA topoisomerase II activity
MOW12_00040	COG0488	(ABC) transporter
MOW12_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MOW12_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MOW12_00115	COG2814	Major facilitator Superfamily
MOW12_00125	COG1012	belongs to the aldehyde dehydrogenase family
MOW12_00130	COG0733	neurotransmitter:sodium symporter activity
MOW12_00140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MOW12_00150	COG0129	dihydroxy-acid dehydratase activity
MOW12_00160	COG0129	dihydroxy-acid dehydratase activity
MOW12_00180	COG2233	PERMEase
MOW12_00190	COG1309	transcriptional regulator
MOW12_00195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MOW12_00270	COG1216	Glycosyl transferase, family 2
MOW12_00285	COG1086	Polysaccharide biosynthesis protein
MOW12_00305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MOW12_00315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MOW12_00325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MOW12_00340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MOW12_00390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MOW12_00400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MOW12_00415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MOW12_00535	COG2801	Transposase and inactivated derivatives
MOW12_00565	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MOW12_00570	COG1335	isochorismatase
MOW12_00580	COG3077	Addiction module antitoxin, RelB DinJ family
MOW12_00585	COG2801	Transposase and inactivated derivatives
MOW12_00615	COG1570	exodeoxyribonuclease VII activity
MOW12_00675	COG1570	exodeoxyribonuclease VII activity
MOW12_00690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MOW12_00695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MOW12_00750	COG3756	Protein conserved in bacteria
MOW12_00785	COG0271	Belongs to the BolA IbaG family
MOW12_00795	COG1192	Involved in chromosome partitioning
MOW12_00810	COG0586	Pfam SNARE associated Golgi protein
MOW12_00815	COG2259	Doxx family
MOW12_00820	COG0519	Catalyzes the synthesis of GMP from XMP
MOW12_00820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MOW12_00825	COG1715	Restriction endonuclease
MOW12_00865	COG0281	malic enzyme
MOW12_00875	COG3179	chitinase
MOW12_00885	COG2837	iron assimilation
MOW12_00895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MOW12_00900	COG1121	(ABC) transporter
MOW12_00950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MOW12_00975	COG0386	Belongs to the glutathione peroxidase family
MOW12_00980	COG0697	spore germination
MOW12_00990	COG0758	DNA mediated transformation
MOW12_01045	COG2814	Major facilitator Superfamily
MOW12_01065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MOW12_01090	COG2814	Major facilitator Superfamily
MOW12_01110	COG1253	flavin adenine dinucleotide binding
MOW12_01120	COG2860	membrane
MOW12_01125	COG0477	Major facilitator Superfamily
MOW12_01135	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_01150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MOW12_01165	COG0606	chelatase, subunit chli
MOW12_01175	COG0347	Belongs to the P(II) protein family
MOW12_01180	COG0004	ammonium transporteR
MOW12_01190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MOW12_01190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MOW12_01205	COG0586	Pfam SNARE associated Golgi protein
MOW12_01230	COG0795	lipopolysaccharide-transporting ATPase activity
MOW12_01235	COG0795	lipopolysaccharide-transporting ATPase activity
MOW12_01240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MOW12_01245	COG0793	Belongs to the peptidase S41A family
MOW12_01260	COG2197	response regulator
MOW12_01270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MOW12_01285	COG4974	Belongs to the 'phage' integrase family
MOW12_01310	COG0772	Belongs to the SEDS family
MOW12_01320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MOW12_01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MOW12_01330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MOW12_01335	COG0494	nUDIX hydrolase
MOW12_01380	COG3275	phosphorelay sensor kinase activity
MOW12_01390	COG0181	hydroxymethylbilane synthase activity
MOW12_01410	COG0824	Thioesterase
MOW12_01495	COG0081	regulation of translation
MOW12_01510	COG0085	RNA polymerase activity
MOW12_01515	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MOW12_01535	COG2056	Na+-H+ antiporter family
MOW12_01555	COG0326	Molecular chaperone. Has ATPase activity
MOW12_01590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MOW12_01600	COG2233	PERMEase
MOW12_01610	COG1250	3-hydroxyacyl-CoA dehydrogenase
MOW12_01610	COG1024	Enoyl-CoA hydratase
MOW12_01630	COG0322	excinuclease ABC activity
MOW12_01640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MOW12_01645	COG1132	(ABC) transporter
MOW12_01660	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MOW12_01670	COG0497	DNA recombination
MOW12_01675	COG3123	guanosine phosphorylase activity
MOW12_01680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MOW12_01690	COG0237	dephospho-CoA kinase activity
MOW12_01740	COG0779	Required for maturation of 30S ribosomal subunits
MOW12_01745	COG0195	Participates in both transcription termination and antitermination
MOW12_01755	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MOW12_01760	COG1320	monovalent cation:proton antiporter activity
MOW12_01765	COG2212	antiporter activity
MOW12_01770	COG1863	multisubunit Na H antiporter MnhE subunit
MOW12_01775	COG0651	ATP synthesis coupled electron transport
MOW12_01780	COG1006	Multisubunit Na H antiporter MnhC subunit
MOW12_01785	COG2111	Na H antiporter
MOW12_01785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MOW12_01800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MOW12_01810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MOW12_01840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MOW12_01845	COG1074	ATP-dependent DNA helicase activity
MOW12_01850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MOW12_01855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MOW12_01870	COG2841	Protein conserved in bacteria
MOW12_01875	COG0789	Transcriptional regulator
MOW12_01885	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MOW12_01895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MOW12_01915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MOW12_01920	COG4535	Mg2 and Co2 transporter CorC
MOW12_01925	COG0425	Belongs to the sulfur carrier protein TusA family
MOW12_01980	COG0644	oxidoreductase
MOW12_01980	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MOW12_01990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MOW12_02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MOW12_02015	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MOW12_02025	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MOW12_02025	COG0493	'glutamate synthase
MOW12_02035	COG2226	methyltransferase
MOW12_02050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MOW12_02080	COG0751	glycine-tRNA ligase activity
MOW12_02090	COG0617	tRNA 3'-terminal CCA addition
MOW12_02090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MOW12_02090	COG0517	IMP dehydrogenase activity
MOW12_02095	COG1983	PspC domain protein
MOW12_02120	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_02125	COG1530	ribonuclease E activity
MOW12_02135	COG0546	phosphoglycolate phosphatase activity
MOW12_02140	COG3971	2-oxopent-4-enoate hydratase activity
MOW12_02145	COG4569	acetaldehyde dehydrogenase (acetylating) activity
MOW12_02170	COG0583	DNA-binding transcription factor activity
MOW12_02175	COG4638	Rieske (2fe-2S)
MOW12_02190	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_02195	COG3384	dioxygenase
MOW12_02200	COG0446	pyridine nucleotide-disulphide oxidoreductase
MOW12_02215	COG0753	catalase activity
MOW12_02225	COG1960	acyl-CoA dehydrogenase activity
MOW12_02245	COG0494	nUDIX hydrolase
MOW12_02260	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MOW12_02275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MOW12_02290	COG0473	3-isopropylmalate dehydrogenase activity
MOW12_02340	COG1560	Kdo2-lipid A biosynthetic process
MOW12_02345	COG0488	(ABC) transporter
MOW12_02350	COG2900	Belongs to the SlyX family
MOW12_02380	COG1929	Belongs to the glycerate kinase type-1 family
MOW12_02390	COG0210	DNA helicase
MOW12_02395	COG0724	RNA recognition motif
MOW12_02410	COG4651	solute:proton antiporter activity
MOW12_02410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MOW12_02435	COG0788	formyltetrahydrofolate deformylase activity
MOW12_02465	COG1295	ribonuclease BN
MOW12_02515	COG1702	phosphate starvation-inducible protein PhoH
MOW12_02565	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MOW12_02570	COG1183	phosphatidylcholine synthase activity
MOW12_02635	COG1607	acyl-coa hydrolase
MOW12_02645	COG1666	GTP binding
MOW12_02665	COG2350	Protein conserved in bacteria
MOW12_02675	COG0613	PHP domain protein
MOW12_02680	COG3781	membrane
MOW12_02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MOW12_02700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MOW12_02710	COG1162	GTPase activity
MOW12_02715	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MOW12_02735	COG3942	CHAP domain
MOW12_02735	COG1388	LysM domain
MOW12_02760	COG3328	transposase activity
MOW12_02765	COG1538	Outer membrane efflux protein
MOW12_02770	COG1136	(ABC) transporter
MOW12_02770	COG0577	efflux transmembrane transporter activity
MOW12_02775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MOW12_02800	COG0028	Belongs to the TPP enzyme family
MOW12_02805	COG0440	acetolactate synthase activity
MOW12_02845	COG2975	iron-sulfur cluster assembly
MOW12_02875	COG0124	histidyl-tRNA synthetase
MOW12_02885	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MOW12_02900	COG3956	TIGRFAM MazG family protein
MOW12_02905	COG1555	photosystem II stabilization
MOW12_02910	COG0617	tRNA 3'-terminal CCA addition
MOW12_02915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MOW12_02930	COG1660	Displays ATPase and GTPase activities
MOW12_02940	COG3028	Belongs to the UPF0307 family
MOW12_02945	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_02960	COG0625	glutathione transferase activity
MOW12_02965	COG1238	metal cluster binding
MOW12_03000	COG0072	phenylalanine-tRNA ligase activity
MOW12_03025	COG0248	Ppx GppA phosphatase
MOW12_03035	COG0037	tRNA processing
MOW12_03080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MOW12_03130	COG2969	positive regulation of protein catabolic process
MOW12_03135	COG0625	glutathione transferase activity
MOW12_03140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MOW12_03150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MOW12_03155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MOW12_03160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MOW12_03190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MOW12_03200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MOW12_03205	COG1408	metallophosphoesterase
MOW12_03215	COG0477	Major facilitator Superfamily
MOW12_03220	COG1272	protein, Hemolysin III
MOW12_03250	COG1250	3-hydroxyacyl-CoA dehydrogenase
MOW12_03250	COG1024	Enoyl-CoA hydratase
MOW12_03255	COG0183	Belongs to the thiolase family
MOW12_03260	COG2207	Transcriptional regulator
MOW12_03265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MOW12_03270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MOW12_03290	COG3385	transposase activity
MOW12_03295	COG0183	Belongs to the thiolase family
MOW12_03315	COG0833	amino acid
MOW12_03325	COG2233	PERMEase
MOW12_03330	COG1217	gtp-binding protein TYPA
MOW12_03335	COG1970	mechanosensitive ion channel activity
MOW12_03340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MOW12_03350	COG1877	trehalose-phosphatase activity
MOW12_03375	COG0363	glucosamine-6-phosphate deaminase activity
MOW12_03405	COG0354	folic acid binding
MOW12_03430	COG3293	Transposase
MOW12_03445	COG0564	pseudouridine synthase activity
MOW12_03460	COG3189	MarR family transcriptional regulator
MOW12_03465	COG2824	Alkylphosphonate utilization operon protein PhnA
MOW12_03475	COG0628	permease
MOW12_03485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MOW12_03490	COG2801	Transposase and inactivated derivatives
MOW12_03495	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_03510	COG3077	Addiction module antitoxin, RelB DinJ family
MOW12_03550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MOW12_03570	COG0730	response to heat
MOW12_03580	COG1196	nuclear chromosome segregation
MOW12_03585	COG3115	cell septum assembly
MOW12_03590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MOW12_03595	COG2193	ferroxidase activity
MOW12_03600	COG2226	methyltransferase
MOW12_03600	COG0596	Alpha beta hydrolase
MOW12_03600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MOW12_03615	COG4106	trans-aconitate 2-methyltransferase activity
MOW12_03625	COG3385	transposase activity
MOW12_03635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MOW12_03640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MOW12_03650	COG0009	L-threonylcarbamoyladenylate synthase
MOW12_03655	COG3101	peptidyl-lysine hydroxylation
MOW12_03660	COG1399	metal-binding, possibly nucleic acid-binding protein
MOW12_03675	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_03685	COG1652	LysM domain
MOW12_03695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MOW12_03710	COG0745	RESPONSE REGULATOR receiver
MOW12_03715	COG2205	protein histidine kinase activity
MOW12_03720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MOW12_03735	COG1752	Esterase of the alpha-beta hydrolase superfamily
MOW12_03750	COG3338	carbonate dehydratase activity
MOW12_03755	COG1126	abc transporter atp-binding protein
MOW12_03760	COG0765	amino acid transport
MOW12_03765	COG0765	amino acid transport
MOW12_03775	COG2323	membrane
MOW12_03805	COG0525	valine-tRNA ligase activity
MOW12_03825	COG0393	Putative heavy-metal-binding
MOW12_03835	COG1538	Outer membrane efflux protein
MOW12_03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MOW12_03850	COG0671	phosphoesterase, PA-phosphatase related
MOW12_03875	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MOW12_03885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MOW12_03890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MOW12_03890	COG1648	precorrin-2 dehydrogenase activity
MOW12_03895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MOW12_03900	COG0531	amino acid
MOW12_03915	COG0321	lipoyl(octanoyl) transferase activity
MOW12_03950	COG0586	Pfam SNARE associated Golgi protein
MOW12_03975	COG3385	transposase activity
MOW12_03995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MOW12_04025	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MOW12_04040	COG0358	DNA primase activity
MOW12_04060	COG0564	pseudouridine synthase activity
MOW12_04075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MOW12_04085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MOW12_04115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MOW12_04115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MOW12_04130	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MOW12_04140	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_04145	COG2072	flavoprotein involved in K transport
MOW12_04160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MOW12_04165	COG1053	succinate dehydrogenase
MOW12_04170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MOW12_04190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MOW12_04200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MOW12_04215	COG0726	polysaccharide deacetylase
MOW12_04215	COG1649	PFAM Uncharacterised BCR, COG1649
MOW12_04220	COG1215	transferase activity, transferring glycosyl groups
MOW12_04230	COG2268	Band 7 protein
MOW12_04245	COG2354	Protein conserved in bacteria
MOW12_04250	COG2321	neutral zinc metallopeptidase
MOW12_04260	COG0589	response to stress
MOW12_04265	COG0110	maltose O-acetyltransferase activity
MOW12_04270	COG0415	Belongs to the DNA photolyase family
MOW12_04285	COG0505	Belongs to the CarA family
MOW12_04300	COG1534	Rna-binding protein
MOW12_04310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MOW12_04320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MOW12_04355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MOW12_04375	COG1597	lipid kinase activity
MOW12_04410	COG2239	Acts as a magnesium transporter
MOW12_04420	COG0501	Belongs to the peptidase M48B family
MOW12_04425	COG0741	lytic transglycosylase activity
MOW12_04425	COG1196	nuclear chromosome segregation
MOW12_04425	COG0739	heme binding
MOW12_04430	COG0037	tRNA processing
MOW12_04440	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MOW12_04445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MOW12_04475	COG1840	ABC-type Fe3 transport system, periplasmic component
MOW12_04480	COG3842	ATPase activity
MOW12_04485	COG1741	Belongs to the pirin family
MOW12_04495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MOW12_04500	COG3739	integral membrane protein
MOW12_04515	COG3706	GGDEF domain
MOW12_04525	COG0302	gtp cyclohydrolase
MOW12_04550	COG0174	glutamine synthetase
MOW12_04560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MOW12_04570	COG0583	DNA-binding transcription factor activity
MOW12_04605	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MOW12_04610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MOW12_04630	COG1115	amino acid carrier protein
MOW12_04635	COG1113	amino acid transport
MOW12_04645	COG0019	diaminopimelate decarboxylase activity
MOW12_04660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MOW12_04670	COG1522	sequence-specific DNA binding
MOW12_04675	COG1280	lysine exporter protein (LysE YggA)
MOW12_04720	COG1671	Belongs to the UPF0178 family
MOW12_04735	COG4591	ABC-type transport system involved in lipoprotein release permease component
MOW12_04740	COG1136	(ABC) transporter
MOW12_04745	COG2333	competence protein COMEC
MOW12_04745	COG0658	competence protein
MOW12_04765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MOW12_04770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MOW12_04775	COG0628	permease
MOW12_04780	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MOW12_04795	COG3385	transposase activity
MOW12_04815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MOW12_04830	COG3385	transposase activity
MOW12_04840	COG0823	Involved in the tonB-independent uptake of proteins
MOW12_04860	COG0824	Thioesterase
MOW12_04865	COG1473	amidohydrolase
MOW12_04880	COG2255	four-way junction helicase activity
MOW12_04905	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MOW12_04905	COG0047	phosphoribosylformylglycinamidine synthase activity
MOW12_04925	COG1024	Enoyl-CoA hydratase
MOW12_04930	COG1056	cytidyltransferase-related domain
MOW12_04930	COG1051	belongs to the nudix hydrolase family
MOW12_04945	COG2353	YceI-like domain
MOW12_04950	COG0583	DNA-binding transcription factor activity
MOW12_04960	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MOW12_04970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MOW12_04975	COG0602	queuosine metabolic process
MOW12_04985	COG4625	pathogenesis
MOW12_04995	COG0583	DNA-binding transcription factor activity
MOW12_05000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MOW12_05005	COG4208	sulfate ABC transporter
MOW12_05020	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MOW12_05030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MOW12_05045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MOW12_05055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MOW12_05070	COG0681	Belongs to the peptidase S26 family
MOW12_05080	COG0571	ribonuclease III activity
MOW12_05085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MOW12_05095	COG1381	Involved in DNA repair and RecF pathway recombination
MOW12_05100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MOW12_05125	COG0436	Aminotransferase
MOW12_05150	COG3300	MHYT domain
MOW12_05150	COG5001	Diguanylate cyclase
MOW12_05160	COG0556	nucleotide-excision repair
MOW12_05190	COG0702	epimerase
MOW12_05195	COG1733	regulation of RNA biosynthetic process
MOW12_05200	COG2814	Major facilitator Superfamily
MOW12_05210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MOW12_05220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MOW12_05225	COG0076	glutamate decarboxylase activity
MOW12_05235	COG0573	inorganic phosphate transmembrane transporter activity
MOW12_05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MOW12_05250	COG0616	signal peptide processing
MOW12_05290	COG2801	Transposase and inactivated derivatives
MOW12_05295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MOW12_05300	COG1686	Belongs to the peptidase S11 family
MOW12_05315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MOW12_05325	COG0583	DNA-binding transcription factor activity
MOW12_05335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MOW12_05340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MOW12_05345	COG1067	ATP-dependent peptidase activity
MOW12_05380	COG1509	lysine 2,3-aminomutase activity
MOW12_05385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MOW12_05390	COG1966	Carbon starvation protein
MOW12_05395	COG2879	small protein
MOW12_05400	COG0714	Associated with various cellular activities
MOW12_05470	COG4626	Terminase
MOW12_05470	COG1802	Transcriptional regulator
MOW12_05495	COG2252	PERMEase
MOW12_05500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MOW12_05510	COG1215	transferase activity, transferring glycosyl groups
MOW12_05520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MOW12_05530	COG0527	aspartate kinase activity
MOW12_05540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MOW12_05555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MOW12_05560	COG0501	Belongs to the peptidase M48B family
MOW12_05575	COG0667	Aldo Keto reductase
MOW12_05585	COG1765	OsmC-like protein
MOW12_05605	COG0540	Belongs to the ATCase OTCase family
MOW12_05620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MOW12_05635	COG4770	biotin carboxylase activity
MOW12_05640	COG1024	Enoyl-CoA hydratase
MOW12_05645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MOW12_05650	COG1960	acyl-CoA dehydrogenase activity
MOW12_05655	COG1309	transcriptional regulator
MOW12_05660	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_05680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MOW12_05690	COG0659	secondary active sulfate transmembrane transporter activity
MOW12_05710	COG2363	Small membrane protein
MOW12_05730	COG0513	Belongs to the DEAD box helicase family
MOW12_05795	COG4783	chaperone-mediated protein folding
MOW12_05810	COG1610	YqeY-like protein
MOW12_05840	COG2815	serine threonine protein kinase
MOW12_05840	COG0515	serine threonine protein kinase
MOW12_05880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MOW12_05880	COG2755	lipolytic protein G-D-S-L family
MOW12_05885	COG0436	Aminotransferase
MOW12_05890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MOW12_05895	COG0386	Belongs to the glutathione peroxidase family
MOW12_05905	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MOW12_05920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MOW12_05930	COG0012	GTP binding
MOW12_05960	COG0204	Acyl-transferase
MOW12_05970	COG0582	viral genome integration into host DNA
MOW12_05975	COG3328	transposase activity
MOW12_06060	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
MOW12_06065	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MOW12_06135	COG2963	transposase activity
MOW12_06145	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MOW12_06155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MOW12_06160	COG0022	dehydrogenase e1 component
MOW12_06165	COG0508	dehydrogenase complex catalyzes the overall conversion of
MOW12_06170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MOW12_06180	COG1063	alcohol dehydrogenase
MOW12_06215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MOW12_06220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MOW12_06230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MOW12_06245	COG2986	histidine ammonia-lyase
MOW12_06285	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_06290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MOW12_06355	COG0183	Belongs to the thiolase family
MOW12_06360	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MOW12_06365	COG3327	negative regulation of DNA-templated transcription, initiation
MOW12_06375	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_06395	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MOW12_06400	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MOW12_06400	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MOW12_06405	COG1254	Belongs to the acylphosphatase family
MOW12_06445	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MOW12_06450	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MOW12_06460	COG2353	YceI-like domain
MOW12_06465	COG0519	Catalyzes the synthesis of GMP from XMP
MOW12_06465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MOW12_06495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MOW12_06500	COG0583	DNA-binding transcription factor activity
MOW12_06510	COG2707	UPF0756 membrane protein
MOW12_06535	COG0802	atpase or kinase
MOW12_06540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MOW12_06550	COG1923	regulation of RNA biosynthetic process
MOW12_06555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MOW12_06565	COG3178	'Phosphotransferase
MOW12_06570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MOW12_06580	COG1192	Involved in chromosome partitioning
MOW12_06585	COG1475	DNA binding
MOW12_06590	COG0811	peptide transport
MOW12_06600	COG1132	(ABC) transporter
MOW12_06605	COG1663	tetraacyldisaccharide 4'-kinase activity
MOW12_06625	COG0084	hydrolase, TatD family'
MOW12_06660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MOW12_06690	COG0776	regulation of translation
MOW12_06700	COG0284	orotidine-5'-phosphate decarboxylase activity
MOW12_06705	COG2431	L-lysine efflux transmembrane transporter activity
MOW12_06720	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MOW12_06725	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MOW12_06745	COG1253	flavin adenine dinucleotide binding
MOW12_06750	COG3385	transposase activity
MOW12_06780	COG0583	DNA-binding transcription factor activity
MOW12_06795	COG3852	Histidine kinase
MOW12_06810	COG0233	cytoplasmic translational termination
MOW12_06815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MOW12_06820	COG0575	Belongs to the CDS family
MOW12_06835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MOW12_06855	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MOW12_06885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MOW12_06890	COG0730	response to heat
MOW12_06895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MOW12_06900	COG2207	Transcriptional regulator
MOW12_06905	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MOW12_06915	COG1960	acyl-CoA dehydrogenase activity
MOW12_06920	COG1960	acyl-CoA dehydrogenase activity
MOW12_06955	COG4890	Cyd operon protein YbgT
MOW12_06960	COG1294	oxidase, subunit
MOW12_06975	COG1585	Membrane protein implicated in regulation of membrane protease activity
MOW12_06985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MOW12_07005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MOW12_07010	COG0569	domain protein
MOW12_07020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MOW12_07040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MOW12_07045	COG0542	response to heat
MOW12_07080	COG0372	Belongs to the citrate synthase family
MOW12_07090	COG1058	Belongs to the CinA family
MOW12_07090	COG1546	Belongs to the CinA family
MOW12_07130	COG2814	Major facilitator Superfamily
MOW12_07145	COG0439	Biotin carboxylase
MOW12_07150	COG0511	ligase activity, forming carbon-carbon bonds
MOW12_07185	COG0596	Alpha beta hydrolase
MOW12_07275	COG2801	Transposase and inactivated derivatives
MOW12_07325	COG0730	response to heat
MOW12_07330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MOW12_07335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MOW12_07345	COG2885	chlorophyll binding
MOW12_07365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MOW12_07395	COG1012	belongs to the aldehyde dehydrogenase family
MOW12_07400	COG1309	transcriptional regulator
MOW12_07405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MOW12_07440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MOW12_07470	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_07480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MOW12_07485	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_07490	COG1846	Transcriptional regulator
MOW12_07495	COG2814	Major facilitator Superfamily
MOW12_07510	COG0318	PFAM AMP-dependent synthetase and ligase
MOW12_07525	COG2226	methyltransferase
MOW12_07525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MOW12_07525	COG0596	Alpha beta hydrolase
MOW12_07530	COG1960	acyl-CoA dehydrogenase activity
MOW12_07540	COG1024	Enoyl-CoA hydratase
MOW12_07545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MOW12_07550	COG0235	Class ii aldolase
MOW12_07560	COG0183	Belongs to the thiolase family
MOW12_07565	COG1250	3-hydroxyacyl-CoA dehydrogenase
MOW12_07570	COG1024	Enoyl-CoA hydratase
MOW12_07575	COG2814	Major facilitator Superfamily
MOW12_07585	COG2814	Major facilitator Superfamily
MOW12_07590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MOW12_07595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MOW12_07600	COG2814	Major facilitator Superfamily
MOW12_07605	COG1960	acyl-CoA dehydrogenase activity
MOW12_07610	COG1960	acyl-CoA dehydrogenase activity
MOW12_07620	COG0644	oxidoreductase
MOW12_07620	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MOW12_07625	COG0515	serine threonine protein kinase
MOW12_07630	COG2116	formate transmembrane transporter activity
MOW12_07635	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MOW12_07650	COG2223	nitrite transmembrane transporter activity
MOW12_07700	COG2814	Major facilitator Superfamily
MOW12_07705	COG0583	DNA-binding transcription factor activity
MOW12_07710	COG4948	Mandelate Racemase Muconate Lactonizing
MOW12_07715	COG4829	muconolactone delta-isomerase
MOW12_07725	COG4638	Rieske (2fe-2S)
MOW12_07730	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MOW12_07735	COG0543	2 iron, 2 sulfur cluster binding
MOW12_07735	COG0633	Ferredoxin
MOW12_07740	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_07745	COG3135	benzoate transporter
MOW12_07750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MOW12_07755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MOW12_07760	COG0183	Belongs to the thiolase family
MOW12_07765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MOW12_07790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MOW12_07795	COG4149	molybdate abc transporter
MOW12_07800	COG0725	ABC transporter, periplasmic molybdate-binding protein
MOW12_07805	COG0303	'Molybdopterin
MOW12_07810	COG0521	Mo-molybdopterin cofactor biosynthetic process
MOW12_07810	COG0315	cyclic pyranopterin monophosphate synthase activity
MOW12_07825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MOW12_07835	COG0243	molybdopterin cofactor binding
MOW12_07840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MOW12_07845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MOW12_07845	COG2146	nitrite reductase [NAD(P)H] activity
MOW12_07850	COG2223	nitrite transmembrane transporter activity
MOW12_07860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MOW12_07860	COG1116	anion transmembrane transporter activity
MOW12_07865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MOW12_07875	COG0640	Transcriptional regulator
MOW12_07895	COG3122	Protein conserved in bacteria
MOW12_07900	COG0668	transmembrane transport
MOW12_07915	COG1132	(ABC) transporter
MOW12_07935	COG2814	Major facilitator Superfamily
MOW12_07960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MOW12_07970	COG1113	amino acid transport
MOW12_07985	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MOW12_07990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MOW12_08040	COG1525	nuclease
MOW12_08050	COG1294	oxidase, subunit
MOW12_08055	COG1271	oxidase subunit
MOW12_08065	COG2814	Major facilitator Superfamily
MOW12_08070	COG2207	Transcriptional regulator
MOW12_08075	COG1960	acyl-CoA dehydrogenase activity
MOW12_08085	COG1629	transport
MOW12_08100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MOW12_08105	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MOW12_08125	COG0583	DNA-binding transcription factor activity
MOW12_08135	COG1346	cytolysis
MOW12_08145	COG1283	sodium-dependent phosphate transmembrane transporter activity
MOW12_08155	COG0693	protein deglycase activity
MOW12_08200	COG0552	protein localization to endoplasmic reticulum
MOW12_08205	COG0612	Peptidase, M16
MOW12_08235	COG0617	tRNA 3'-terminal CCA addition
MOW12_08235	COG0517	IMP dehydrogenase activity
MOW12_08235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MOW12_08240	COG0133	tryptophan synthase activity
MOW12_08250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MOW12_08270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MOW12_08325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MOW12_08355	COG0822	iron-sulfur transferase activity
MOW12_08360	COG0316	Belongs to the HesB IscA family
MOW12_08390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MOW12_08405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MOW12_08410	COG0702	epimerase
MOW12_08415	COG0268	Binds directly to 16S ribosomal RNA
MOW12_08435	COG1011	Hydrolase
MOW12_08440	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MOW12_08450	COG2137	regulation of response to DNA damage stimulus
MOW12_08465	COG0772	Belongs to the SEDS family
MOW12_08480	COG0148	phosphopyruvate hydratase activity
MOW12_08510	COG1902	pentaerythritol trinitrate reductase activity
MOW12_08510	COG0446	pyridine nucleotide-disulphide oxidoreductase
MOW12_08530	COG1960	acyl-CoA dehydrogenase activity
MOW12_08540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MOW12_08545	COG1027	Aspartate ammonia-lyase
MOW12_08555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MOW12_08565	COG0506	proline dehydrogenase activity
MOW12_08565	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MOW12_08565	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MOW12_08585	COG3698	Phosphodiester glycosidase
MOW12_08650	COG0697	spore germination
MOW12_08675	COG0424	maF-like protein
MOW12_08680	COG2850	peptidyl-arginine hydroxylation
MOW12_08685	COG4585	Histidine kinase
MOW12_08695	COG0069	glutamate synthase activity
MOW12_08725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MOW12_08730	COG1454	alcohol dehydrogenase
MOW12_08735	COG0824	Thioesterase
MOW12_08740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MOW12_08750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MOW12_08755	COG2030	dehydratase
MOW12_08765	COG0183	Belongs to the thiolase family
MOW12_08780	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MOW12_08790	COG3135	benzoate transporter
MOW12_08800	COG0589	response to stress
MOW12_08805	COG0589	response to stress
MOW12_08815	COG0308	aminopeptidase N
MOW12_08850	COG0786	glutamate:sodium symporter activity
MOW12_08895	COG0477	Major facilitator Superfamily
MOW12_08910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MOW12_08930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MOW12_08935	COG1960	acyl-CoA dehydrogenase activity
MOW12_08955	COG3781	membrane
MOW12_08965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MOW12_08980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MOW12_09005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MOW12_09010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MOW12_09015	COG1845	cytochrome c oxidase, subunit III
MOW12_09020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MOW12_09030	COG0360	Binds together with S18 to 16S ribosomal RNA
MOW12_09035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MOW12_09050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MOW12_09065	COG1305	Transglutaminase-like
MOW12_09075	COG2308	Evidence 4 Homologs of previously reported genes of
MOW12_09115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MOW12_09120	COG0138	bifunctional purine biosynthesis protein purh
MOW12_09145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MOW12_09150	COG2011	ABC-type metal ion transport system permease component
MOW12_09205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MOW12_09215	COG4122	O-methyltransferase activity
MOW12_09250	COG1137	ATPase activity
MOW12_09255	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MOW12_09265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MOW12_09270	COG0517	IMP dehydrogenase activity
MOW12_09270	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MOW12_09295	COG1643	Atp-dependent helicase
MOW12_09325	COG3634	alkyl hydroperoxide reductase activity
MOW12_09335	COG2391	methyltransferase activity
MOW12_09360	COG2070	2-Nitropropane dioxygenase
MOW12_09375	COG1278	Cold shock
MOW12_09430	COG1309	transcriptional regulator
MOW12_09435	COG0596	Alpha beta hydrolase
MOW12_09485	COG0352	thiamine-phosphate diphosphorylase activity
MOW12_09520	COG0612	Peptidase, M16
MOW12_09530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MOW12_09540	COG0739	heme binding
MOW12_09555	COG1187	pseudouridine synthase activity
MOW12_09570	COG1686	Belongs to the peptidase S11 family
MOW12_09575	COG1252	NADH dehydrogenase
MOW12_09580	COG1047	Peptidyl-prolyl cis-trans
MOW12_09605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MOW12_09610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MOW12_09620	COG0693	protein deglycase activity
MOW12_09625	COG1960	acyl-CoA dehydrogenase activity
MOW12_09630	COG1301	dicarboxylic acid transport
MOW12_09640	COG3139	Protein of unknown function (DUF1315)
MOW12_09645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MOW12_09650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MOW12_09685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MOW12_09695	COG1720	tRNA m6t6A37 methyltransferase activity
MOW12_09710	COG0789	Transcriptional regulator
MOW12_09715	COG0431	NADPH-dependent FMN reductase
MOW12_09720	COG0798	PFAM Bile acid sodium symporter
MOW12_09730	COG0640	Transcriptional regulator
MOW12_09740	COG0826	peptidase U32
MOW12_09745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MOW12_09750	COG3634	alkyl hydroperoxide reductase activity
MOW12_09770	COG3385	transposase activity
MOW12_09775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MOW12_09830	COG1131	(ABC) transporter
MOW12_09835	COG0842	Transport permease protein
MOW12_09850	COG2951	lytic endotransglycosylase activity
MOW12_09875	COG0052	Belongs to the universal ribosomal protein uS2 family
MOW12_09895	COG3293	Transposase
MOW12_09900	COG2175	clavaminate synthase activity
MOW12_09910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MOW12_09915	COG1960	acyl-CoA dehydrogenase activity
MOW12_09940	COG3385	transposase activity
MOW12_09945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MOW12_09950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MOW12_09955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MOW12_09975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MOW12_10080	COG0446	pyridine nucleotide-disulphide oxidoreductase
MOW12_10080	COG1902	pentaerythritol trinitrate reductase activity
MOW12_10095	COG3706	GGDEF domain
MOW12_10095	COG4251	negative regulation of phosphorylation
MOW12_10095	COG5001	Diguanylate cyclase
MOW12_10095	COG2203	Gaf domain
MOW12_10100	COG0418	dihydroorotase activity
MOW12_10105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MOW12_10130	COG0833	amino acid
MOW12_10160	COG4172	Belongs to the ABC transporter superfamily
MOW12_10165	COG4239	(ABC) transporter, permease
MOW12_10170	COG4174	ABC transporter (Permease)
MOW12_10175	COG4166	transmembrane transport
MOW12_10180	COG1388	LysM domain
MOW12_10180	COG0741	lytic transglycosylase activity
MOW12_10195	COG2816	NAD+ diphosphatase activity
MOW12_10230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MOW12_10235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MOW12_10245	COG0006	proline dipeptidase activity
MOW12_10250	COG3079	Belongs to the UPF0149 family
MOW12_10280	COG0277	FAD linked oxidase domain protein
MOW12_10290	COG2186	Transcriptional regulator
MOW12_10315	COG3328	transposase activity
MOW12_10330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MOW12_10345	COG2234	aminopeptidase activity
MOW12_10355	COG3384	dioxygenase
MOW12_10365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MOW12_10370	COG2878	Part of a membrane complex involved in electron transport
MOW12_10375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MOW12_10400	COG0768	penicillin binding
MOW12_10405	COG0742	ribosomal rna small subunit methyltransferase
MOW12_10420	COG0830	nickel cation binding
MOW12_10435	COG3328	transposase activity
MOW12_10445	COG0804	urea catabolic process
MOW12_10480	COG3015	lipoprotein NlpE involved in copper resistance
MOW12_10500	COG1253	flavin adenine dinucleotide binding
MOW12_10525	COG3118	belongs to the thioredoxin family
MOW12_10555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MOW12_10560	COG1773	rubredoxin
MOW12_10565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MOW12_10575	COG0583	DNA-binding transcription factor activity
MOW12_10585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MOW12_10595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MOW12_10600	COG4181	ATPase activity
MOW12_10625	COG4771	TonB-dependent receptor
MOW12_10675	COG0306	phosphate transporter
MOW12_10685	COG2066	Belongs to the glutaminase family
MOW12_10695	COG0477	Major facilitator Superfamily
MOW12_10725	COG2199	diguanylate cyclase activity
MOW12_10725	COG2203	Gaf domain
MOW12_10735	COG4681	YaeQ
MOW12_10740	COG0523	cobalamin synthesis protein
MOW12_10770	COG0583	DNA-binding transcription factor activity
MOW12_10775	COG2814	Major facilitator Superfamily
MOW12_10785	COG1607	acyl-coa hydrolase
MOW12_10795	COG1752	Esterase of the alpha-beta hydrolase superfamily
MOW12_10800	COG2059	Chromate
MOW12_10805	COG1115	amino acid carrier protein
MOW12_10810	COG0786	glutamate:sodium symporter activity
MOW12_10825	COG2814	Major facilitator Superfamily
MOW12_10830	COG1289	transmembrane transporter activity
MOW12_10840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MOW12_10900	COG1376	ErfK ybiS ycfS ynhG family protein
MOW12_10905	COG2832	Protein of unknown function (DUF454)
MOW12_10915	COG5510	response to toxic substance
MOW12_10935	COG0643	Histidine kinase
MOW12_10935	COG0784	Response regulator, receiver
MOW12_10935	COG2198	Histidine kinase
MOW12_10940	COG0840	transmembrane signaling receptor activity
MOW12_10960	COG2801	Transposase and inactivated derivatives
MOW12_10980	COG0442	prolyl-tRNA aminoacylation
MOW12_11015	COG2358	TRAP transporter, solute receptor (TAXI family
MOW12_11030	COG0489	protein tyrosine kinase activity
MOW12_11035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOW12_11035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOW12_11045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOW12_11045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOW12_11065	COG0004	ammonium transporteR
MOW12_11080	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MOW12_11095	COG2081	HI0933 family
MOW12_11110	COG0668	transmembrane transport
MOW12_11135	COG0583	DNA-binding transcription factor activity
MOW12_11140	COG1278	Cold shock
MOW12_11155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MOW12_11160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MOW12_11165	COG0713	ATP synthesis coupled electron transport
MOW12_11170	COG0839	Belongs to the complex I subunit 6 family
MOW12_11175	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MOW12_11180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MOW12_11190	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MOW12_11210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MOW12_11220	COG0142	geranyltranstransferase activity
MOW12_11225	COG2828	Protein conserved in bacteria
MOW12_11230	COG1113	amino acid transport
MOW12_11250	COG0625	glutathione transferase activity
MOW12_11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MOW12_11300	COG1530	ribonuclease E activity
MOW12_11305	COG0424	maF-like protein
MOW12_11310	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MOW12_11315	COG1792	Involved in formation and maintenance of cell shape
MOW12_11320	COG1077	Cell shape determining protein MreB Mrl
MOW12_11325	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MOW12_11335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MOW12_11365	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MOW12_11380	COG1215	transferase activity, transferring glycosyl groups
MOW12_11385	COG0726	polysaccharide deacetylase
MOW12_11385	COG1649	PFAM Uncharacterised BCR, COG1649
MOW12_11420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MOW12_11425	COG2050	protein possibly involved in aromatic compounds catabolism
MOW12_11445	COG0420	3'-5' exonuclease activity
MOW12_11475	COG0735	belongs to the Fur family
MOW12_11480	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MOW12_11485	COG2914	Belongs to the UPF0125 (RnfH) family
MOW12_11535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MOW12_11545	COG0210	DNA helicase
MOW12_11550	COG2885	chlorophyll binding
MOW12_11555	COG0204	Acyl-transferase
MOW12_11565	COG0850	regulation of cytokinetic process
MOW12_11570	COG2894	cell division
MOW12_11585	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MOW12_11585	COG1674	ftsk spoiiie
MOW12_11590	COG0492	ferredoxin-NADP+ reductase activity
MOW12_11595	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MOW12_11605	COG0456	acetyltransferase
MOW12_11630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MOW12_11645	COG1981	membrane
MOW12_11650	COG1113	amino acid transport
MOW12_11655	COG0251	oxidation-reduction process
MOW12_11680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MOW12_11680	COG0351	phosphomethylpyrimidine kinase
MOW12_11680	COG0352	thiamine-phosphate diphosphorylase activity
MOW12_11695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MOW12_11700	COG2076	Multidrug Resistance protein
MOW12_11710	COG2132	Multicopper oxidase
MOW12_11720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MOW12_11735	COG4269	membrane
MOW12_11755	COG1968	undecaprenyl-diphosphatase activity
MOW12_11760	COG1214	PFAM Peptidase M22, glycoprotease
MOW12_11770	COG0494	nUDIX hydrolase
MOW12_11795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MOW12_11800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MOW12_11860	COG2199	diguanylate cyclase activity
MOW12_11890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MOW12_11895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MOW12_11910	COG0450	alkyl hydroperoxide reductase
MOW12_11925	COG0285	dihydrofolate synthase activity
MOW12_11930	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MOW12_11975	COG4206	TonB-dependent receptor
MOW12_11980	COG2096	Adenosyltransferase
MOW12_12000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MOW12_12005	COG2315	Protein conserved in bacteria
MOW12_12015	COG1113	amino acid transport
MOW12_12025	COG0745	RESPONSE REGULATOR receiver
MOW12_12030	COG2205	protein histidine kinase activity
MOW12_12040	COG1960	acyl-CoA dehydrogenase activity
MOW12_12045	COG1960	acyl-CoA dehydrogenase activity
MOW12_12100	COG3547	Transposase (IS116 IS110 IS902 family)
MOW12_12105	COG0675	Transposase, IS605 OrfB family
MOW12_12130	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MOW12_12145	COG1216	Glycosyl transferase, family 2
MOW12_12180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MOW12_12185	COG5002	protein histidine kinase activity
MOW12_12200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MOW12_12210	COG1704	LemA family
MOW12_12225	COG1862	Preprotein translocase
MOW12_12240	COG3385	transposase activity
MOW12_12250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MOW12_12265	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MOW12_12270	COG0784	Response regulator, receiver
MOW12_12270	COG5002	protein histidine kinase activity
MOW12_12270	COG2205	protein histidine kinase activity
MOW12_12275	COG1024	Enoyl-CoA hydratase
MOW12_12285	COG3622	Belongs to the hyi family
MOW12_12310	COG0697	spore germination
MOW12_12315	COG2814	Major facilitator Superfamily
MOW12_12360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MOW12_12435	COG1785	Belongs to the alkaline phosphatase family
MOW12_12440	COG1785	Belongs to the alkaline phosphatase family
MOW12_12515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MOW12_12520	COG3385	transposase activity
MOW12_12525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MOW12_12530	COG0084	hydrolase, TatD family'
MOW12_12545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MOW12_12560	COG0793	Belongs to the peptidase S41A family
MOW12_12590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MOW12_12595	COG0857	belongs to the CobB CobQ family
MOW12_12595	COG0280	phosphate acetyltransferase
MOW12_12620	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MOW12_12620	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MOW12_12635	COG0740	serine-type endopeptidase activity
MOW12_12645	COG4771	TonB-dependent receptor
MOW12_12650	COG4774	siderophore transport
MOW12_12655	COG3128	pkhd-type hydroxylase
MOW12_12665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MOW12_12670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MOW12_12675	COG2813	Specifically methylates the guanine in position
MOW12_12675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MOW12_12740	COG3040	lipid binding
MOW12_12770	COG0179	Fumarylacetoacetate (FAA) hydrolase
MOW12_12805	COG0557	exoribonuclease II activity
MOW12_12810	COG0339	signal peptide processing
MOW12_12815	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MOW12_12845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MOW12_12870	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MOW12_12875	COG1960	acyl-CoA dehydrogenase activity
MOW12_12880	COG2072	flavoprotein involved in K transport
MOW12_12890	COG0202	RNA polymerase activity
MOW12_12895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MOW12_12930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MOW12_12940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MOW12_12945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MOW12_12980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MOW12_13010	COG0088	Forms part of the polypeptide exit tunnel
MOW12_13045	COG1959	2 iron, 2 sulfur cluster binding
MOW12_13065	COG1301	dicarboxylic acid transport
MOW12_13070	COG1946	Acyl-CoA thioesterase
MOW12_13075	COG2937	Belongs to the GPAT DAPAT family
MOW12_13085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MOW12_13090	COG1040	competence protein
MOW12_13105	COG0598	Magnesium transport protein CorA
MOW12_13115	COG2854	intermembrane phospholipid transfer
MOW12_13120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MOW12_13125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MOW12_13130	COG1127	ABC transporter
MOW12_13155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MOW12_13160	COG0408	coproporphyrinogen oxidase activity
MOW12_13175	COG1960	acyl-CoA dehydrogenase activity
MOW12_13180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MOW12_13190	COG0534	Mate efflux family protein
MOW12_13195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MOW12_13200	COG0254	rRNA binding
MOW12_13205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MOW12_13250	COG1192	Involved in chromosome partitioning
MOW12_13255	COG0628	permease
MOW12_13265	COG2814	Major facilitator Superfamily
MOW12_13280	COG0277	FAD linked oxidase domain protein
MOW12_13285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MOW12_13310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MOW12_13320	COG3547	Transposase (IS116 IS110 IS902 family)
MOW12_13330	COG5380	lipid catabolic process
MOW12_13335	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MOW12_13340	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MOW12_13345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MOW12_13350	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MOW12_13355	COG0335	large ribosomal subunit rRNA binding
MOW12_13365	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MOW12_13370	COG0228	four-way junction DNA binding
MOW12_13385	COG2165	general secretion pathway protein
MOW12_13395	COG0194	GDP metabolic process
MOW12_13400	COG1758	RNA polymerase activity
MOW12_13405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MOW12_13425	COG3307	-O-antigen
MOW12_13445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MOW12_13450	COG1704	LemA family
MOW12_13460	COG0493	'glutamate synthase
MOW12_13465	COG0067	glutamate synthase
MOW12_13465	COG0069	glutamate synthase activity
MOW12_13465	COG0070	glutamate synthase
MOW12_13535	COG3385	transposase activity
MOW12_13540	COG2226	methyltransferase
MOW12_13550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MOW12_13555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MOW12_13570	COG0275	rRNA processing
MOW12_13575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MOW12_13585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MOW12_13605	COG0488	(ABC) transporter
MOW12_13615	COG4221	oxidoreductase activity
MOW12_13640	COG0427	acetyl-CoA hydrolase
MOW12_13670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MOW12_13690	COG0697	spore germination
MOW12_13705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MOW12_13745	COG3158	transport of potassium into the cell
MOW12_13790	COG2826	transposase and inactivated derivatives, IS30 family
MOW12_13815	COG1324	tolerance protein
MOW12_13820	COG0673	inositol 2-dehydrogenase activity
MOW12_13840	COG2826	transposase and inactivated derivatives, IS30 family
MOW12_13875	COG0629	single-stranded DNA binding
MOW12_13880	COG2814	Major facilitator Superfamily
MOW12_13890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MOW12_13905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MOW12_13920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MOW12_13940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MOW12_13945	COG3162	membrane
MOW12_13950	COG2205	protein histidine kinase activity
MOW12_13950	COG0784	Response regulator, receiver
MOW12_13970	COG0431	NADPH-dependent FMN reductase
MOW12_13980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MOW12_13985	COG0668	transmembrane transport
MOW12_13990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MOW12_13995	COG1519	Transferase
MOW12_14000	COG1902	pentaerythritol trinitrate reductase activity
MOW12_14005	COG0640	Transcriptional regulator
MOW12_14025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MOW12_14055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MOW12_14055	COG0426	domain, Protein
MOW12_14060	COG2119	membrane
MOW12_14090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MOW12_14100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MOW12_14110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MOW12_14115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MOW12_14120	COG0189	ligase activity
MOW12_14135	COG4115	mRNA cleavage
MOW12_14185	COG0708	Exodeoxyribonuclease III
MOW12_14190	COG1393	Belongs to the ArsC family
MOW12_14205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MOW12_14210	COG3706	GGDEF domain
MOW12_14215	COG0625	glutathione transferase activity
MOW12_14255	COG1247	-acetyltransferase
MOW12_14265	COG4266	Belongs to the allantoicase family
MOW12_14270	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MOW12_14280	COG0471	metal ion transport
MOW12_14325	COG3150	esterase
MOW12_14335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MOW12_14340	COG2918	glutathione biosynthetic process
MOW12_14355	COG2733	membrane
MOW12_14360	COG0436	Aminotransferase
MOW12_14365	COG0534	Mate efflux family protein
MOW12_14420	COG0753	catalase activity
MOW12_14440	COG3830	Belongs to the UPF0237 family
MOW12_14440	COG0560	Phosphoserine phosphatase
MOW12_14455	COG0385	Bile acid
MOW12_14460	COG1335	isochorismatase
MOW12_14465	COG2814	Major facilitator Superfamily
MOW12_14470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MOW12_14480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MOW12_14485	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MOW12_14490	COG2983	Belongs to the UPF0260 family
MOW12_14495	COG5487	UPF0391 membrane protein
MOW12_14510	COG1194	a g-specific adenine glycosylase
MOW12_14515	COG0739	heme binding
MOW12_14525	COG2818	Glycosylase
MOW12_14530	COG1064	alcohol dehydrogenase
MOW12_14550	COG3023	N-Acetylmuramoyl-L-alanine amidase
MOW12_14560	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MOW12_14565	COG1309	transcriptional regulator
MOW12_14575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MOW12_14580	COG0546	phosphoglycolate phosphatase activity
MOW12_14585	COG1028	Short-chain dehydrogenase reductase Sdr
MOW12_14625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MOW12_14625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MOW12_14630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MOW12_14635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MOW12_14640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MOW12_14645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MOW12_14650	COG1116	anion transmembrane transporter activity
MOW12_14665	COG1309	transcriptional regulator
MOW12_14675	COG0196	riboflavin kinase activity
MOW12_14680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MOW12_14685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MOW12_14690	COG1047	Peptidyl-prolyl cis-trans
MOW12_14700	COG2133	pyrroloquinoline quinone binding
MOW12_14705	COG2814	Major facilitator Superfamily
MOW12_14735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MOW12_14745	COG0657	acetylesterase activity
MOW12_14780	COG2951	lytic endotransglycosylase activity
MOW12_14785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MOW12_14805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MOW12_14830	COG0861	Integral membrane protein TerC family
MOW12_14835	COG0402	S-adenosylhomocysteine deaminase activity
MOW12_14855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MOW12_14860	COG1230	cation diffusion facilitator family transporter
MOW12_14900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MOW12_14905	COG0594	ribonuclease P activity
MOW12_15135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MOW12_15160	COG4974	Belongs to the 'phage' integrase family
MOW12_15185	COG2184	nucleotidyltransferase activity
MOW12_15230	COG1192	Involved in chromosome partitioning
MOW12_15245	COG2963	transposase activity
MOW12_15265	COG1414	Transcriptional regulator
MOW12_15270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MOW12_15275	COG1414	Transcriptional regulator
MOW12_15280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MOW12_15285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MOW12_15290	COG0183	Belongs to the thiolase family
MOW12_15315	COG1660	Displays ATPase and GTPase activities
MOW12_15340	COG2801	Transposase and inactivated derivatives
MOW12_15345	COG0488	(ABC) transporter
MOW12_15355	COG0488	(ABC) transporter
MOW12_15365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MOW12_15440	COG1373	ATPase (AAA superfamily