locus-tag	class	description
G0027_00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0027_00055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G0027_00070	COG1113	amino acid transport
G0027_00080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0027_00090	COG2814	Major facilitator Superfamily
G0027_00110	COG1132	(ABC) transporter
G0027_00125	COG0668	transmembrane transport
G0027_00130	COG3122	Protein conserved in bacteria
G0027_00150	COG0640	Transcriptional regulator
G0027_00160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0027_00165	COG1116	anion transmembrane transporter activity
G0027_00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_00175	COG2223	nitrite transmembrane transporter activity
G0027_00180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_00185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_00190	COG0243	molybdopterin cofactor binding
G0027_00200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G0027_00215	COG0521	Mo-molybdopterin cofactor biosynthetic process
G0027_00215	COG0315	cyclic pyranopterin monophosphate synthase activity
G0027_00230	COG4149	molybdate abc transporter
G0027_00235	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G0027_00240	COG0583	DNA-binding transcription factor activity
G0027_00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_00265	COG0183	Belongs to the thiolase family
G0027_00270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_00275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_00285	COG0583	DNA-binding transcription factor activity
G0027_00290	COG2814	Major facilitator Superfamily
G0027_00320	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_00330	COG2223	nitrite transmembrane transporter activity
G0027_00340	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G0027_00345	COG2116	formate transmembrane transporter activity
G0027_00350	COG0515	serine threonine protein kinase
G0027_00355	COG0644	oxidoreductase
G0027_00355	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0027_00365	COG1960	acyl-CoA dehydrogenase activity
G0027_00370	COG1960	acyl-CoA dehydrogenase activity
G0027_00375	COG2814	Major facilitator Superfamily
G0027_00380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_00385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_00390	COG2814	Major facilitator Superfamily
G0027_00400	COG2814	Major facilitator Superfamily
G0027_00405	COG1024	Enoyl-CoA hydratase
G0027_00410	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_00415	COG0183	Belongs to the thiolase family
G0027_00425	COG0235	Class ii aldolase
G0027_00430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0027_00435	COG1024	Enoyl-CoA hydratase
G0027_00445	COG1960	acyl-CoA dehydrogenase activity
G0027_00460	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_00470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_00475	COG2814	Major facilitator Superfamily
G0027_00485	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_00490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G0027_00500	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_00530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_00565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0027_00570	COG1309	transcriptional regulator
G0027_00575	COG1012	belongs to the aldehyde dehydrogenase family
G0027_00605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G0027_00640	COG2885	chlorophyll binding
G0027_00650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G0027_00655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_00660	COG0730	response to heat
G0027_00665	COG3293	Transposase
G0027_00705	COG2801	Transposase and inactivated derivatives
G0027_00795	COG0596	Alpha beta hydrolase
G0027_00830	COG0511	ligase activity, forming carbon-carbon bonds
G0027_00835	COG0439	Biotin carboxylase
G0027_00850	COG2814	Major facilitator Superfamily
G0027_00855	COG3038	cytochrome b561
G0027_00885	COG1546	Belongs to the CinA family
G0027_00885	COG1058	Belongs to the CinA family
G0027_00895	COG0372	Belongs to the citrate synthase family
G0027_00930	COG0542	response to heat
G0027_00935	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G0027_00965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G0027_00975	COG0569	domain protein
G0027_00980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G0027_01000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G0027_01010	COG1585	Membrane protein implicated in regulation of membrane protease activity
G0027_01025	COG1294	oxidase, subunit
G0027_01030	COG4890	Cyd operon protein YbgT
G0027_01065	COG1960	acyl-CoA dehydrogenase activity
G0027_01070	COG1960	acyl-CoA dehydrogenase activity
G0027_01080	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0027_01085	COG2207	Transcriptional regulator
G0027_01090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0027_01095	COG0730	response to heat
G0027_01100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0027_01130	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0027_01150	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_01165	COG0575	Belongs to the CDS family
G0027_01170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G0027_01175	COG0233	cytoplasmic translational termination
G0027_01190	COG3852	Histidine kinase
G0027_01205	COG0583	DNA-binding transcription factor activity
G0027_01235	COG1253	flavin adenine dinucleotide binding
G0027_01255	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G0027_01260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G0027_01275	COG2431	L-lysine efflux transmembrane transporter activity
G0027_01280	COG0284	orotidine-5'-phosphate decarboxylase activity
G0027_01290	COG0776	regulation of translation
G0027_01320	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G0027_01355	COG0084	hydrolase, TatD family'
G0027_01375	COG1663	tetraacyldisaccharide 4'-kinase activity
G0027_01380	COG1132	(ABC) transporter
G0027_01390	COG0811	peptide transport
G0027_01395	COG1475	DNA binding
G0027_01400	COG1192	Involved in chromosome partitioning
G0027_01410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G0027_01415	COG3178	'Phosphotransferase
G0027_01425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_01430	COG1923	regulation of RNA biosynthetic process
G0027_01440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G0027_01445	COG0802	atpase or kinase
G0027_01470	COG2707	UPF0756 membrane protein
G0027_01480	COG0583	DNA-binding transcription factor activity
G0027_01485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_01515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0027_01515	COG0519	Catalyzes the synthesis of GMP from XMP
G0027_01520	COG2353	YceI-like domain
G0027_01530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G0027_01535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G0027_01575	COG1254	Belongs to the acylphosphatase family
G0027_01580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G0027_01580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G0027_01585	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G0027_01605	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_01615	COG3327	negative regulation of DNA-templated transcription, initiation
G0027_01620	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G0027_01625	COG0183	Belongs to the thiolase family
G0027_01630	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_01635	COG1024	Enoyl-CoA hydratase
G0027_01650	COG0204	Acyl-transferase
G0027_01680	COG0012	GTP binding
G0027_01690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G0027_01705	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G0027_01715	COG0386	Belongs to the glutathione peroxidase family
G0027_01720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G0027_01725	COG0436	Aminotransferase
G0027_01730	COG2755	lipolytic protein G-D-S-L family
G0027_01730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G0027_01770	COG2815	serine threonine protein kinase
G0027_01770	COG0515	serine threonine protein kinase
G0027_01800	COG1610	YqeY-like protein
G0027_01815	COG4783	chaperone-mediated protein folding
G0027_01880	COG0513	Belongs to the DEAD box helicase family
G0027_01900	COG2363	Small membrane protein
G0027_01920	COG0659	secondary active sulfate transmembrane transporter activity
G0027_01930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G0027_01950	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_01955	COG1309	transcriptional regulator
G0027_01960	COG1960	acyl-CoA dehydrogenase activity
G0027_01965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G0027_01970	COG1024	Enoyl-CoA hydratase
G0027_01975	COG4770	biotin carboxylase activity
G0027_01990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_02005	COG0540	Belongs to the ATCase OTCase family
G0027_02025	COG1765	OsmC-like protein
G0027_02035	COG0667	Aldo Keto reductase
G0027_02050	COG0501	Belongs to the peptidase M48B family
G0027_02055	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G0027_02070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G0027_02080	COG0527	aspartate kinase activity
G0027_02090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G0027_02100	COG1215	transferase activity, transferring glycosyl groups
G0027_02110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G0027_02115	COG2252	PERMEase
G0027_02140	COG0714	Associated with various cellular activities
G0027_02145	COG2879	small protein
G0027_02150	COG1966	Carbon starvation protein
G0027_02155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G0027_02160	COG1509	lysine 2,3-aminomutase activity
G0027_02195	COG1067	ATP-dependent peptidase activity
G0027_02200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G0027_02205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G0027_02210	COG0583	DNA-binding transcription factor activity
G0027_02220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G0027_02235	COG1686	Belongs to the peptidase S11 family
G0027_02240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G0027_02275	COG0616	signal peptide processing
G0027_02280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G0027_02290	COG0573	inorganic phosphate transmembrane transporter activity
G0027_02300	COG0076	glutamate decarboxylase activity
G0027_02305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G0027_02345	COG3385	transposase activity
G0027_02360	COG4372	Transposase
G0027_02465	COG3617	BRO family, N-terminal domain
G0027_02490	COG0582	viral genome integration into host DNA
G0027_02495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G0027_02505	COG2814	Major facilitator Superfamily
G0027_02510	COG1733	regulation of RNA biosynthetic process
G0027_02515	COG0702	epimerase
G0027_02545	COG0556	nucleotide-excision repair
G0027_02555	COG3300	MHYT domain
G0027_02555	COG5001	Diguanylate cyclase
G0027_02580	COG0436	Aminotransferase
G0027_02605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G0027_02610	COG1381	Involved in DNA repair and RecF pathway recombination
G0027_02620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G0027_02625	COG0571	ribonuclease III activity
G0027_02635	COG0681	Belongs to the peptidase S26 family
G0027_02650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G0027_02660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G0027_02675	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G0027_02685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0027_02700	COG4208	sulfate ABC transporter
G0027_02705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G0027_02710	COG0583	DNA-binding transcription factor activity
G0027_02730	COG0602	queuosine metabolic process
G0027_02735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G0027_02745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G0027_02750	COG2353	YceI-like domain
G0027_02755	COG1051	belongs to the nudix hydrolase family
G0027_02755	COG1056	cytidyltransferase-related domain
G0027_02760	COG1024	Enoyl-CoA hydratase
G0027_02765	COG0778	Nitroreductase
G0027_02780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G0027_02780	COG0047	phosphoribosylformylglycinamidine synthase activity
G0027_02800	COG2310	stress, protein
G0027_02830	COG1358	cellular component organization or biogenesis
G0027_02860	COG2255	four-way junction helicase activity
G0027_02870	COG0824	Thioesterase
G0027_02890	COG0823	Involved in the tonB-independent uptake of proteins
G0027_02910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0027_02940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0027_02945	COG0628	permease
G0027_02950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G0027_02955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G0027_02975	COG0658	competence protein
G0027_02975	COG2333	competence protein COMEC
G0027_02980	COG1136	(ABC) transporter
G0027_02985	COG4591	ABC-type transport system involved in lipoprotein release permease component
G0027_03000	COG1671	Belongs to the UPF0178 family
G0027_03040	COG1280	lysine exporter protein (LysE YggA)
G0027_03045	COG1522	sequence-specific DNA binding
G0027_03055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G0027_03070	COG0019	diaminopimelate decarboxylase activity
G0027_03080	COG1113	amino acid transport
G0027_03085	COG1115	amino acid carrier protein
G0027_03105	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G0027_03110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G0027_03145	COG0583	DNA-binding transcription factor activity
G0027_03155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G0027_03165	COG0174	glutamine synthetase
G0027_03170	COG0512	Glutamine amidotransferase of anthranilate synthase
G0027_03190	COG0302	gtp cyclohydrolase
G0027_03200	COG3706	GGDEF domain
G0027_03215	COG3739	integral membrane protein
G0027_03220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G0027_03230	COG1741	Belongs to the pirin family
G0027_03235	COG3842	ATPase activity
G0027_03240	COG1840	ABC-type Fe3 transport system, periplasmic component
G0027_03270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G0027_03300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G0027_03310	COG2184	nucleotidyltransferase activity
G0027_03370	COG0582	viral genome integration into host DNA
G0027_03380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_03400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_03405	COG1074	ATP-dependent DNA helicase activity
G0027_03410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G0027_03430	COG4372	Transposase
G0027_03470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G0027_03480	COG1061	Type III restriction enzyme res subunit
G0027_03485	COG1002	Type II restriction enzyme, methylase subunits
G0027_03520	COG4372	Transposase
G0027_03535	COG4372	Transposase
G0027_03575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G0027_03585	COG0037	tRNA processing
G0027_03590	COG1196	nuclear chromosome segregation
G0027_03590	COG0741	lytic transglycosylase activity
G0027_03590	COG0739	heme binding
G0027_03595	COG0501	Belongs to the peptidase M48B family
G0027_03605	COG2239	Acts as a magnesium transporter
G0027_03615	COG0584	glycerophosphoryl diester phosphodiesterase
G0027_03640	COG1597	lipid kinase activity
G0027_03660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G0027_03695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G0027_03705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0027_03715	COG1534	Rna-binding protein
G0027_03730	COG0505	Belongs to the CarA family
G0027_03745	COG0415	Belongs to the DNA photolyase family
G0027_03750	COG0110	maltose O-acetyltransferase activity
G0027_03755	COG0589	response to stress
G0027_03765	COG2321	neutral zinc metallopeptidase
G0027_03770	COG2354	Protein conserved in bacteria
G0027_03785	COG2268	Band 7 protein
G0027_03795	COG1215	transferase activity, transferring glycosyl groups
G0027_03800	COG0726	polysaccharide deacetylase
G0027_03800	COG1649	PFAM Uncharacterised BCR, COG1649
G0027_03810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G0027_03820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G0027_03835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G0027_03840	COG1053	succinate dehydrogenase
G0027_03845	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G0027_03860	COG2072	flavoprotein involved in K transport
G0027_03865	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_03875	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G0027_03890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0027_03890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G0027_03920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_03930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G0027_03945	COG0564	pseudouridine synthase activity
G0027_03955	COG0358	DNA primase activity
G0027_03970	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G0027_04000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G0027_04040	COG0586	Pfam SNARE associated Golgi protein
G0027_04065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G0027_04075	COG0321	lipoyl(octanoyl) transferase activity
G0027_04090	COG0531	amino acid
G0027_04095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G0027_04100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G0027_04100	COG1648	precorrin-2 dehydrogenase activity
G0027_04105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G0027_04115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G0027_04140	COG0671	phosphoesterase, PA-phosphatase related
G0027_04145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_04155	COG1538	Outer membrane efflux protein
G0027_04165	COG0393	Putative heavy-metal-binding
G0027_04170	COG0393	Putative heavy-metal-binding
G0027_04185	COG0525	valine-tRNA ligase activity
G0027_04215	COG2323	membrane
G0027_04225	COG0765	amino acid transport
G0027_04230	COG0765	amino acid transport
G0027_04235	COG1126	abc transporter atp-binding protein
G0027_04240	COG3338	carbonate dehydratase activity
G0027_04255	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0027_04270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_04275	COG2205	protein histidine kinase activity
G0027_04280	COG0745	RESPONSE REGULATOR receiver
G0027_04295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G0027_04325	COG1652	LysM domain
G0027_04335	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_04350	COG1399	metal-binding, possibly nucleic acid-binding protein
G0027_04355	COG3101	peptidyl-lysine hydroxylation
G0027_04360	COG0009	L-threonylcarbamoyladenylate synthase
G0027_04370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G0027_04375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G0027_04390	COG4106	trans-aconitate 2-methyltransferase activity
G0027_04405	COG2226	methyltransferase
G0027_04405	COG0596	Alpha beta hydrolase
G0027_04405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_04410	COG2193	ferroxidase activity
G0027_04415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G0027_04420	COG3115	cell septum assembly
G0027_04425	COG1196	nuclear chromosome segregation
G0027_04435	COG0730	response to heat
G0027_04455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G0027_04485	COG2801	Transposase and inactivated derivatives
G0027_04490	COG2801	Transposase and inactivated derivatives
G0027_04505	COG0628	permease
G0027_04515	COG2824	Alkylphosphonate utilization operon protein PhnA
G0027_04520	COG3189	MarR family transcriptional regulator
G0027_04535	COG0564	pseudouridine synthase activity
G0027_04570	COG0354	folic acid binding
G0027_04600	COG0363	glucosamine-6-phosphate deaminase activity
G0027_04610	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G0027_04615	COG1877	trehalose-phosphatase activity
G0027_04625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_04630	COG1970	mechanosensitive ion channel activity
G0027_04635	COG1217	gtp-binding protein TYPA
G0027_04640	COG2233	PERMEase
G0027_04650	COG0833	amino acid
G0027_04670	COG0183	Belongs to the thiolase family
G0027_04685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_04690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_04695	COG2207	Transcriptional regulator
G0027_04700	COG0183	Belongs to the thiolase family
G0027_04705	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_04705	COG1024	Enoyl-CoA hydratase
G0027_04730	COG1272	protein, Hemolysin III
G0027_04735	COG0477	Major facilitator Superfamily
G0027_04745	COG1408	metallophosphoesterase
G0027_04750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0027_04760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G0027_04790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G0027_04795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G0027_04800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G0027_04810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G0027_04815	COG0625	glutathione transferase activity
G0027_04820	COG2969	positive regulation of protein catabolic process
G0027_04875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0027_04920	COG0037	tRNA processing
G0027_04930	COG0248	Ppx GppA phosphatase
G0027_04955	COG0072	phenylalanine-tRNA ligase activity
G0027_04990	COG1238	metal cluster binding
G0027_04995	COG0625	glutathione transferase activity
G0027_05010	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_05015	COG3028	Belongs to the UPF0307 family
G0027_05025	COG1660	Displays ATPase and GTPase activities
G0027_05040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G0027_05045	COG0617	tRNA 3'-terminal CCA addition
G0027_05050	COG1555	photosystem II stabilization
G0027_05055	COG3956	TIGRFAM MazG family protein
G0027_05070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_05080	COG0124	histidyl-tRNA synthetase
G0027_05110	COG2975	iron-sulfur cluster assembly
G0027_05150	COG0440	acetolactate synthase activity
G0027_05155	COG0028	Belongs to the TPP enzyme family
G0027_05185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_05190	COG0577	efflux transmembrane transporter activity
G0027_05190	COG1136	(ABC) transporter
G0027_05195	COG1538	Outer membrane efflux protein
G0027_05210	COG2826	transposase and inactivated derivatives, IS30 family
G0027_05235	COG1324	tolerance protein
G0027_05240	COG0673	inositol 2-dehydrogenase activity
G0027_05260	COG2826	transposase and inactivated derivatives, IS30 family
G0027_05285	COG1324	tolerance protein
G0027_05335	COG1324	tolerance protein
G0027_05360	COG2826	transposase and inactivated derivatives, IS30 family
G0027_05385	COG1324	tolerance protein
G0027_05390	COG0673	inositol 2-dehydrogenase activity
G0027_05410	COG2826	transposase and inactivated derivatives, IS30 family
G0027_05425	COG3942	CHAP domain
G0027_05425	COG1388	LysM domain
G0027_05450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G0027_05455	COG1162	GTPase activity
G0027_05465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G0027_05475	COG3385	transposase activity
G0027_05480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G0027_05490	COG3781	membrane
G0027_05495	COG0613	PHP domain protein
G0027_05505	COG2350	Protein conserved in bacteria
G0027_05525	COG1666	GTP binding
G0027_05535	COG1607	acyl-coa hydrolase
G0027_05600	COG1183	phosphatidylcholine synthase activity
G0027_05605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G0027_05645	COG0741	lytic transglycosylase activity
G0027_05645	COG1196	nuclear chromosome segregation
G0027_05645	COG0739	heme binding
G0027_05655	COG1702	phosphate starvation-inducible protein PhoH
G0027_05700	COG1295	ribonuclease BN
G0027_05730	COG0788	formyltetrahydrofolate deformylase activity
G0027_05755	COG4651	solute:proton antiporter activity
G0027_05755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G0027_05770	COG0724	RNA recognition motif
G0027_05775	COG0210	DNA helicase
G0027_05785	COG1929	Belongs to the glycerate kinase type-1 family
G0027_05815	COG2900	Belongs to the SlyX family
G0027_05820	COG0488	(ABC) transporter
G0027_05825	COG1560	Kdo2-lipid A biosynthetic process
G0027_05880	COG0473	3-isopropylmalate dehydrogenase activity
G0027_05895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G0027_05910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G0027_05925	COG0494	nUDIX hydrolase
G0027_05945	COG1960	acyl-CoA dehydrogenase activity
G0027_05955	COG0753	catalase activity
G0027_05970	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_05975	COG3384	dioxygenase
G0027_05980	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_05995	COG4638	Rieske (2fe-2S)
G0027_06000	COG0583	DNA-binding transcription factor activity
G0027_06025	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G0027_06030	COG3971	2-oxopent-4-enoate hydratase activity
G0027_06035	COG0546	phosphoglycolate phosphatase activity
G0027_06045	COG1530	ribonuclease E activity
G0027_06050	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_06075	COG1983	PspC domain protein
G0027_06080	COG0517	IMP dehydrogenase activity
G0027_06080	COG0617	tRNA 3'-terminal CCA addition
G0027_06080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0027_06090	COG0751	glycine-tRNA ligase activity
G0027_06135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G0027_06160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_06160	COG0493	'glutamate synthase
G0027_06170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G0027_06180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G0027_06195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G0027_06205	COG0644	oxidoreductase
G0027_06205	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0027_06220	COG2826	transposase and inactivated derivatives, IS30 family
G0027_06230	COG2826	transposase and inactivated derivatives, IS30 family
G0027_06255	COG0425	Belongs to the sulfur carrier protein TusA family
G0027_06260	COG4535	Mg2 and Co2 transporter CorC
G0027_06265	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G0027_06285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G0027_06295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G0027_06305	COG0789	Transcriptional regulator
G0027_06310	COG2841	Protein conserved in bacteria
G0027_06325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G0027_06330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_06335	COG1074	ATP-dependent DNA helicase activity
G0027_06340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G0027_06370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0027_06380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G0027_06395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0027_06395	COG2111	Na H antiporter
G0027_06400	COG1006	Multisubunit Na H antiporter MnhC subunit
G0027_06405	COG0651	ATP synthesis coupled electron transport
G0027_06410	COG1863	multisubunit Na H antiporter MnhE subunit
G0027_06415	COG2212	antiporter activity
G0027_06420	COG1320	monovalent cation:proton antiporter activity
G0027_06425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G0027_06435	COG0195	Participates in both transcription termination and antitermination
G0027_06440	COG0779	Required for maturation of 30S ribosomal subunits
G0027_06490	COG0237	dephospho-CoA kinase activity
G0027_06500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0027_06505	COG3123	guanosine phosphorylase activity
G0027_06510	COG0497	DNA recombination
G0027_06520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G0027_06535	COG1132	(ABC) transporter
G0027_06540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G0027_06550	COG0322	excinuclease ABC activity
G0027_06570	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0027_06570	COG1024	Enoyl-CoA hydratase
G0027_06580	COG2233	PERMEase
G0027_06590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G0027_06615	COG0326	Molecular chaperone. Has ATPase activity
G0027_06630	COG2056	Na+-H+ antiporter family
G0027_06650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G0027_06655	COG0085	RNA polymerase activity
G0027_06670	COG0081	regulation of translation
G0027_06755	COG0824	Thioesterase
G0027_06775	COG0181	hydroxymethylbilane synthase activity
G0027_06785	COG3275	phosphorelay sensor kinase activity
G0027_06830	COG0494	nUDIX hydrolase
G0027_06835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G0027_06840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G0027_06845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0027_06855	COG0772	Belongs to the SEDS family
G0027_06880	COG4974	Belongs to the 'phage' integrase family
G0027_06895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G0027_06905	COG2197	response regulator
G0027_06920	COG0793	Belongs to the peptidase S41A family
G0027_06925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G0027_06930	COG0795	lipopolysaccharide-transporting ATPase activity
G0027_06935	COG0795	lipopolysaccharide-transporting ATPase activity
G0027_06960	COG0586	Pfam SNARE associated Golgi protein
G0027_06975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0027_06975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0027_06985	COG0004	ammonium transporteR
G0027_06990	COG0347	Belongs to the P(II) protein family
G0027_07000	COG0606	chelatase, subunit chli
G0027_07015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0027_07030	COG0318	PFAM AMP-dependent synthetase and ligase
G0027_07040	COG0477	Major facilitator Superfamily
G0027_07045	COG2860	membrane
G0027_07055	COG1253	flavin adenine dinucleotide binding
G0027_07075	COG2814	Major facilitator Superfamily
G0027_07090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0027_07110	COG2814	Major facilitator Superfamily
G0027_07160	COG0758	DNA mediated transformation
G0027_07170	COG0697	spore germination
G0027_07175	COG0386	Belongs to the glutathione peroxidase family
G0027_07200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G0027_07250	COG1121	(ABC) transporter
G0027_07255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G0027_07265	COG2837	iron assimilation
G0027_07290	COG0281	malic enzyme
G0027_07330	COG1715	Restriction endonuclease
G0027_07335	COG0519	Catalyzes the synthesis of GMP from XMP
G0027_07335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0027_07340	COG2259	Doxx family
G0027_07345	COG0586	Pfam SNARE associated Golgi protein
G0027_07360	COG1192	Involved in chromosome partitioning
G0027_07370	COG0271	Belongs to the BolA IbaG family
G0027_07405	COG3756	Protein conserved in bacteria
G0027_07500	COG0642	Histidine kinase
G0027_07505	COG0745	RESPONSE REGULATOR receiver
G0027_07510	COG2194	sulfuric ester hydrolase activity
G0027_07515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G0027_07520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0027_07535	COG1570	exodeoxyribonuclease VII activity
G0027_07560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0027_07565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0027_07575	COG0659	secondary active sulfate transmembrane transporter activity
G0027_07595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0027_07775	COG0583	DNA-binding transcription factor activity
G0027_08000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_08015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G0027_08030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G0027_08040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G0027_08090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0027_08105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G0027_08115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G0027_08125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G0027_08130	COG0438	transferase activity, transferring glycosyl groups
G0027_08140	COG0367	asparagine synthase
G0027_08190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G0027_08245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0027_08250	COG1309	transcriptional regulator
G0027_08260	COG2233	PERMEase
G0027_08275	COG0129	dihydroxy-acid dehydratase activity
G0027_08285	COG0129	dihydroxy-acid dehydratase activity
G0027_08295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G0027_08305	COG0733	neurotransmitter:sodium symporter activity
G0027_08320	COG1012	belongs to the aldehyde dehydrogenase family
G0027_08330	COG2814	Major facilitator Superfamily
G0027_08380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G0027_08385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G0027_08410	COG0488	(ABC) transporter
G0027_08415	COG1063	alcohol dehydrogenase
G0027_08430	COG0187	DNA topoisomerase II activity
G0027_08440	COG0592	DNA-directed DNA polymerase activity
G0027_08445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0027_08455	COG0594	ribonuclease P activity
G0027_08460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G0027_08465	COG0706	membrane insertase activity
G0027_08500	COG1230	cation diffusion facilitator family transporter
G0027_08505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G0027_08520	COG0402	S-adenosylhomocysteine deaminase activity
G0027_08525	COG0861	Integral membrane protein TerC family
G0027_08535	COG2388	GCN5-related N-acetyl-transferase
G0027_08555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0027_08575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G0027_08585	COG2951	lytic endotransglycosylase activity
G0027_08620	COG0657	acetylesterase activity
G0027_08630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G0027_08660	COG2814	Major facilitator Superfamily
G0027_08675	COG1047	Peptidyl-prolyl cis-trans
G0027_08680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G0027_08685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G0027_08690	COG0196	riboflavin kinase activity
G0027_08705	COG1309	transcriptional regulator
G0027_08715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_08720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0027_08725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G0027_08725	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G0027_08760	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_08765	COG0546	phosphoglycolate phosphatase activity
G0027_08770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G0027_08780	COG1309	transcriptional regulator
G0027_08785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G0027_08795	COG3023	N-Acetylmuramoyl-L-alanine amidase
G0027_08815	COG1064	alcohol dehydrogenase
G0027_08820	COG2818	Glycosylase
G0027_08835	COG1194	a g-specific adenine glycosylase
G0027_08850	COG5487	UPF0391 membrane protein
G0027_08855	COG2983	Belongs to the UPF0260 family
G0027_08860	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G0027_08865	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G0027_08875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G0027_08880	COG2814	Major facilitator Superfamily
G0027_08885	COG1335	isochorismatase
G0027_08890	COG0385	Bile acid
G0027_08905	COG3830	Belongs to the UPF0237 family
G0027_08905	COG0560	Phosphoserine phosphatase
G0027_08925	COG0753	catalase activity
G0027_08980	COG2175	clavaminate synthase activity
G0027_08985	COG0534	Mate efflux family protein
G0027_08990	COG0436	Aminotransferase
G0027_08995	COG2733	membrane
G0027_09010	COG2918	glutathione biosynthetic process
G0027_09015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G0027_09025	COG3150	esterase
G0027_09065	COG0471	metal ion transport
G0027_09080	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G0027_09085	COG4266	Belongs to the allantoicase family
G0027_09090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_09095	COG1247	-acetyltransferase
G0027_09135	COG0625	glutathione transferase activity
G0027_09145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G0027_09160	COG1393	Belongs to the ArsC family
G0027_09165	COG0708	Exodeoxyribonuclease III
G0027_09210	COG4115	mRNA cleavage
G0027_09220	COG0189	ligase activity
G0027_09225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G0027_09230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0027_09240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G0027_09250	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G0027_09280	COG2119	membrane
G0027_09285	COG0426	domain, Protein
G0027_09285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_09310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G0027_09330	COG0640	Transcriptional regulator
G0027_09335	COG1902	pentaerythritol trinitrate reductase activity
G0027_09340	COG1519	Transferase
G0027_09345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0027_09350	COG0668	transmembrane transport
G0027_09355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0027_09380	COG0784	Response regulator, receiver
G0027_09380	COG2205	protein histidine kinase activity
G0027_09385	COG3162	membrane
G0027_09390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_09410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0027_09425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G0027_09440	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0027_09450	COG2814	Major facilitator Superfamily
G0027_09455	COG0629	single-stranded DNA binding
G0027_09470	COG4372	Transposase
G0027_09535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_09565	COG2132	Multicopper oxidase
G0027_09580	COG2801	Transposase and inactivated derivatives
G0027_09585	COG3077	Addiction module antitoxin, RelB DinJ family
G0027_09615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G0027_09640	COG3158	transport of potassium into the cell
G0027_09685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G0027_09700	COG0697	spore germination
G0027_09720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G0027_09750	COG0427	acetyl-CoA hydrolase
G0027_09775	COG4221	oxidoreductase activity
G0027_09785	COG0488	(ABC) transporter
G0027_09815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0027_09825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0027_09830	COG0275	rRNA processing
G0027_09845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G0027_09850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G0027_09860	COG2226	methyltransferase
G0027_09865	COG3385	transposase activity
G0027_09925	COG0069	glutamate synthase activity
G0027_09925	COG0067	glutamate synthase
G0027_09925	COG0070	glutamate synthase
G0027_09930	COG0493	'glutamate synthase
G0027_09940	COG1704	LemA family
G0027_09945	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G0027_09955	COG2801	Transposase and inactivated derivatives
G0027_09980	COG3307	-O-antigen
G0027_10000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0027_10005	COG1758	RNA polymerase activity
G0027_10010	COG0194	GDP metabolic process
G0027_10065	COG4969	Belongs to the N-Me-Phe pilin family
G0027_10075	COG0228	four-way junction DNA binding
G0027_10080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G0027_10090	COG0335	large ribosomal subunit rRNA binding
G0027_10135	COG5380	lipid catabolic process
G0027_10140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G0027_10165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0027_10170	COG0277	FAD linked oxidase domain protein
G0027_10185	COG2814	Major facilitator Superfamily
G0027_10195	COG0628	permease
G0027_10200	COG1192	Involved in chromosome partitioning
G0027_10225	COG2226	methyltransferase
G0027_10245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0027_10250	COG0254	rRNA binding
G0027_10255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0027_10260	COG0534	Mate efflux family protein
G0027_10270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0027_10275	COG1960	acyl-CoA dehydrogenase activity
G0027_10295	COG0408	coproporphyrinogen oxidase activity
G0027_10300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0027_10325	COG1127	ABC transporter
G0027_10330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G0027_10335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G0027_10340	COG2854	intermembrane phospholipid transfer
G0027_10350	COG0598	Magnesium transport protein CorA
G0027_10365	COG1040	competence protein
G0027_10370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G0027_10380	COG2937	Belongs to the GPAT DAPAT family
G0027_10385	COG1946	Acyl-CoA thioesterase
G0027_10390	COG1301	dicarboxylic acid transport
G0027_10410	COG1959	2 iron, 2 sulfur cluster binding
G0027_10420	COG0433	COG0433 Predicted ATPase
G0027_10445	COG0088	Forms part of the polypeptide exit tunnel
G0027_10475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G0027_10510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G0027_10515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G0027_10525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G0027_10560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G0027_10565	COG0202	RNA polymerase activity
G0027_10575	COG2072	flavoprotein involved in K transport
G0027_10580	COG1960	acyl-CoA dehydrogenase activity
G0027_10585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G0027_10610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G0027_10615	COG0697	spore germination
G0027_10650	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G0027_10655	COG0339	signal peptide processing
G0027_10660	COG0557	exoribonuclease II activity
G0027_10695	COG0179	Fumarylacetoacetate (FAA) hydrolase
G0027_10725	COG3040	lipid binding
G0027_10790	COG2813	Specifically methylates the guanine in position
G0027_10790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_10795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_10800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G0027_10810	COG3128	pkhd-type hydroxylase
G0027_10815	COG4774	siderophore transport
G0027_10820	COG4771	TonB-dependent receptor
G0027_10830	COG0740	serine-type endopeptidase activity
G0027_10845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G0027_10845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G0027_10885	COG2801	Transposase and inactivated derivatives
G0027_10890	COG0280	phosphate acetyltransferase
G0027_10890	COG0857	belongs to the CobB CobQ family
G0027_10895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G0027_10910	COG0596	Alpha beta hydrolase
G0027_10910	COG2226	methyltransferase
G0027_10910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0027_10925	COG0793	Belongs to the peptidase S41A family
G0027_10955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G0027_10970	COG0084	hydrolase, TatD family'
G0027_10975	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G0027_10980	COG3385	transposase activity
G0027_10985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G0027_11020	COG1785	Belongs to the alkaline phosphatase family
G0027_11025	COG1785	Belongs to the alkaline phosphatase family
G0027_11115	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G0027_11125	COG0732	type I restriction modification DNA specificity domain
G0027_11135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
G0027_11155	COG1058	Belongs to the CinA family
G0027_11155	COG1546	Belongs to the CinA family
G0027_11175	COG2814	Major facilitator Superfamily
G0027_11180	COG0697	spore germination
G0027_11205	COG3622	Belongs to the hyi family
G0027_11215	COG1024	Enoyl-CoA hydratase
G0027_11220	COG5002	protein histidine kinase activity
G0027_11220	COG2205	protein histidine kinase activity
G0027_11220	COG0784	Response regulator, receiver
G0027_11225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0027_11240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0027_11260	COG1862	Preprotein translocase
G0027_11275	COG1704	LemA family
G0027_11285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G0027_11300	COG5002	protein histidine kinase activity
G0027_11305	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G0027_11325	COG0438	transferase activity, transferring glycosyl groups
G0027_11375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G0027_11405	COG3223	Belongs to the PsiE family
G0027_11410	COG1960	acyl-CoA dehydrogenase activity
G0027_11415	COG1960	acyl-CoA dehydrogenase activity
G0027_11430	COG2205	protein histidine kinase activity
G0027_11435	COG0745	RESPONSE REGULATOR receiver
G0027_11460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G0027_11465	COG3385	transposase activity
G0027_11485	COG2096	Adenosyltransferase
G0027_11490	COG4206	TonB-dependent receptor
G0027_11535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G0027_11540	COG0285	dihydrofolate synthase activity
G0027_11565	COG0450	alkyl hydroperoxide reductase
G0027_11580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G0027_11585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G0027_11610	COG2885	chlorophyll binding
G0027_11615	COG2199	diguanylate cyclase activity
G0027_11680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G0027_11685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G0027_11705	COG0494	nUDIX hydrolase
G0027_11715	COG1214	PFAM Peptidase M22, glycoprotease
G0027_11720	COG1968	undecaprenyl-diphosphatase activity
G0027_11740	COG4269	membrane
G0027_11755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G0027_11765	COG2132	Multicopper oxidase
G0027_11780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G0027_11795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0027_11795	COG0352	thiamine-phosphate diphosphorylase activity
G0027_11795	COG0351	phosphomethylpyrimidine kinase
G0027_11820	COG0251	oxidation-reduction process
G0027_11825	COG1113	amino acid transport
G0027_11830	COG1981	membrane
G0027_11845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G0027_11870	COG0456	acetyltransferase
G0027_11880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G0027_11885	COG0492	ferredoxin-NADP+ reductase activity
G0027_11890	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G0027_11890	COG1674	ftsk spoiiie
G0027_11905	COG2894	cell division
G0027_11910	COG0850	regulation of cytokinetic process
G0027_11920	COG0204	Acyl-transferase
G0027_11925	COG2885	chlorophyll binding
G0027_11930	COG0210	DNA helicase
G0027_11940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0027_11990	COG2914	Belongs to the UPF0125 (RnfH) family
G0027_11995	COG3385	transposase activity
G0027_12000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0027_12005	COG0735	belongs to the Fur family
G0027_12035	COG0420	3'-5' exonuclease activity
G0027_12055	COG2050	protein possibly involved in aromatic compounds catabolism
G0027_12060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G0027_12100	COG1414	Transcriptional regulator
G0027_12105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_12110	COG1414	Transcriptional regulator
G0027_12115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0027_12120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0027_12125	COG0183	Belongs to the thiolase family
G0027_12130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G0027_12135	COG0596	Alpha beta hydrolase
G0027_12140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G0027_12145	COG3485	protocatechuate 3,4-dioxygenase
G0027_12150	COG3485	protocatechuate 3,4-dioxygenase
G0027_12180	COG1960	acyl-CoA dehydrogenase activity
G0027_12185	COG3320	Male sterility
G0027_12185	COG1022	Amp-dependent synthetase and ligase
G0027_12190	COG1012	belongs to the aldehyde dehydrogenase family
G0027_12195	COG1024	Enoyl-CoA hydratase
G0027_12200	COG2814	Major facilitator Superfamily
G0027_12215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G0027_12235	COG3177	Filamentation induced by cAMP protein fic
G0027_12265	COG1649	PFAM Uncharacterised BCR, COG1649
G0027_12265	COG0726	polysaccharide deacetylase
G0027_12270	COG1215	transferase activity, transferring glycosyl groups
G0027_12285	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G0027_12325	COG3328	transposase activity
G0027_12335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0027_12340	COG0154	amidase activity
G0027_12345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0027_12350	COG1077	Cell shape determining protein MreB Mrl
G0027_12355	COG1792	Involved in formation and maintenance of cell shape
G0027_12360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G0027_12365	COG0424	maF-like protein
G0027_12370	COG1530	ribonuclease E activity
G0027_12380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G0027_12420	COG0625	glutathione transferase activity
G0027_12430	COG0675	Transposase, IS605 OrfB family
G0027_12445	COG1113	amino acid transport
G0027_12450	COG2828	Protein conserved in bacteria
G0027_12455	COG0142	geranyltranstransferase activity
G0027_12465	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_12485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G0027_12495	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G0027_12500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_12505	COG0839	Belongs to the complex I subunit 6 family
G0027_12510	COG0713	ATP synthesis coupled electron transport
G0027_12515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0027_12520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0027_12535	COG1278	Cold shock
G0027_12540	COG1278	Cold shock
G0027_12545	COG0583	DNA-binding transcription factor activity
G0027_12575	COG0668	transmembrane transport
G0027_12585	COG2081	HI0933 family
G0027_12620	COG0004	ammonium transporteR
G0027_12635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0027_12635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0027_12640	COG0489	protein tyrosine kinase activity
G0027_12655	COG2358	TRAP transporter, solute receptor (TAXI family
G0027_12690	COG0442	prolyl-tRNA aminoacylation
G0027_12725	COG0840	transmembrane signaling receptor activity
G0027_12730	COG0643	Histidine kinase
G0027_12730	COG0784	Response regulator, receiver
G0027_12730	COG2198	Histidine kinase
G0027_12745	COG5510	response to toxic substance
G0027_12755	COG2832	Protein of unknown function (DUF454)
G0027_12760	COG1376	ErfK ybiS ycfS ynhG family protein
G0027_12815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G0027_12825	COG1289	transmembrane transporter activity
G0027_12830	COG2814	Major facilitator Superfamily
G0027_12845	COG0786	glutamate:sodium symporter activity
G0027_12850	COG1115	amino acid carrier protein
G0027_12855	COG2059	Chromate
G0027_12860	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0027_12870	COG1607	acyl-coa hydrolase
G0027_12880	COG2814	Major facilitator Superfamily
G0027_12885	COG0583	DNA-binding transcription factor activity
G0027_12915	COG0523	cobalamin synthesis protein
G0027_12920	COG4681	YaeQ
G0027_12930	COG2203	Gaf domain
G0027_12930	COG2199	diguanylate cyclase activity
G0027_12960	COG0477	Major facilitator Superfamily
G0027_12970	COG2066	Belongs to the glutaminase family
G0027_12980	COG0306	phosphate transporter
G0027_13020	COG4771	TonB-dependent receptor
G0027_13025	COG0500	methyltransferase
G0027_13055	COG4181	ATPase activity
G0027_13060	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G0027_13070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0027_13080	COG0583	DNA-binding transcription factor activity
G0027_13090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0027_13095	COG1773	rubredoxin
G0027_13100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G0027_13130	COG3118	belongs to the thioredoxin family
G0027_13150	COG1253	flavin adenine dinucleotide binding
G0027_13170	COG3015	lipoprotein NlpE involved in copper resistance
G0027_13185	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_13205	COG0804	urea catabolic process
G0027_13210	COG3385	transposase activity
G0027_13220	COG3328	transposase activity
G0027_13235	COG0830	nickel cation binding
G0027_13250	COG0742	ribosomal rna small subunit methyltransferase
G0027_13255	COG0768	penicillin binding
G0027_13280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G0027_13285	COG2878	Part of a membrane complex involved in electron transport
G0027_13290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G0027_13300	COG3384	dioxygenase
G0027_13310	COG2234	aminopeptidase activity
G0027_13320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G0027_13355	COG2186	Transcriptional regulator
G0027_13365	COG0277	FAD linked oxidase domain protein
G0027_13395	COG3079	Belongs to the UPF0149 family
G0027_13400	COG0006	proline dipeptidase activity
G0027_13410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_13415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0027_13450	COG2816	NAD+ diphosphatase activity
G0027_13465	COG0741	lytic transglycosylase activity
G0027_13465	COG1388	LysM domain
G0027_13470	COG4166	transmembrane transport
G0027_13475	COG4174	ABC transporter (Permease)
G0027_13480	COG4239	(ABC) transporter, permease
G0027_13485	COG4172	Belongs to the ABC transporter superfamily
G0027_13515	COG0833	amino acid
G0027_13535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G0027_13540	COG0418	dihydroorotase activity
G0027_13545	COG5001	Diguanylate cyclase
G0027_13545	COG4251	negative regulation of phosphorylation
G0027_13545	COG3706	GGDEF domain
G0027_13545	COG2203	Gaf domain
G0027_13560	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_13560	COG1902	pentaerythritol trinitrate reductase activity
G0027_13600	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G0027_13620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0027_13625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G0027_13630	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G0027_13655	COG1960	acyl-CoA dehydrogenase activity
G0027_13660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G0027_13670	COG2175	clavaminate synthase activity
G0027_13690	COG0052	Belongs to the universal ribosomal protein uS2 family
G0027_13715	COG2951	lytic endotransglycosylase activity
G0027_13730	COG0842	Transport permease protein
G0027_13735	COG1131	(ABC) transporter
G0027_13790	COG3385	transposase activity
G0027_13795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0027_13815	COG3634	alkyl hydroperoxide reductase activity
G0027_13820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0027_13825	COG0826	peptidase U32
G0027_13835	COG0640	Transcriptional regulator
G0027_13845	COG0798	PFAM Bile acid sodium symporter
G0027_13850	COG0431	NADPH-dependent FMN reductase
G0027_13855	COG0789	Transcriptional regulator
G0027_13880	COG1720	tRNA m6t6A37 methyltransferase activity
G0027_13890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G0027_13925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0027_13930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G0027_13935	COG3139	Protein of unknown function (DUF1315)
G0027_13950	COG1301	dicarboxylic acid transport
G0027_13955	COG1960	acyl-CoA dehydrogenase activity
G0027_13960	COG0693	protein deglycase activity
G0027_13970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G0027_13975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G0027_14000	COG1047	Peptidyl-prolyl cis-trans
G0027_14005	COG1252	NADH dehydrogenase
G0027_14010	COG1686	Belongs to the peptidase S11 family
G0027_14025	COG1187	pseudouridine synthase activity
G0027_14035	COG0739	heme binding
G0027_14045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0027_14055	COG0612	Peptidase, M16
G0027_14065	COG3385	transposase activity
G0027_14095	COG0352	thiamine-phosphate diphosphorylase activity
G0027_14110	COG2801	Transposase and inactivated derivatives
G0027_14120	COG1028	Short-chain dehydrogenase reductase Sdr
G0027_14125	COG2801	Transposase and inactivated derivatives
G0027_14155	COG0596	Alpha beta hydrolase
G0027_14160	COG1309	transcriptional regulator
G0027_14195	COG1278	Cold shock
G0027_14215	COG2070	2-Nitropropane dioxygenase
G0027_14240	COG2391	methyltransferase activity
G0027_14245	COG3385	transposase activity
G0027_14255	COG3634	alkyl hydroperoxide reductase activity
G0027_14285	COG1643	Atp-dependent helicase
G0027_14310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G0027_14310	COG0517	IMP dehydrogenase activity
G0027_14315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G0027_14325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G0027_14330	COG1137	ATPase activity
G0027_14375	COG4122	O-methyltransferase activity
G0027_14385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G0027_14400	COG1454	alcohol dehydrogenase
G0027_14430	COG2011	ABC-type metal ion transport system permease component
G0027_14435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G0027_14455	COG0138	bifunctional purine biosynthesis protein purh
G0027_14460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G0027_14500	COG2308	Evidence 4 Homologs of previously reported genes of
G0027_14510	COG1305	Transglutaminase-like
G0027_14525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G0027_14540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G0027_14545	COG0360	Binds together with S18 to 16S ribosomal RNA
G0027_14555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G0027_14560	COG1845	cytochrome c oxidase, subunit III
G0027_14565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G0027_14570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G0027_14595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0027_14610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G0027_14620	COG3781	membrane
G0027_14640	COG1960	acyl-CoA dehydrogenase activity
G0027_14660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G0027_14670	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G0027_14685	COG0477	Major facilitator Superfamily
G0027_14730	COG0786	glutamate:sodium symporter activity
G0027_14765	COG0308	aminopeptidase N
G0027_14775	COG0589	response to stress
G0027_14780	COG0589	response to stress
G0027_14790	COG3135	benzoate transporter
G0027_14800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G0027_14815	COG0183	Belongs to the thiolase family
G0027_14825	COG2030	dehydratase
G0027_14830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G0027_14840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G0027_14845	COG0824	Thioesterase
G0027_14850	COG1454	alcohol dehydrogenase
G0027_14855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G0027_14875	COG0069	glutamate synthase activity
G0027_14885	COG4585	Histidine kinase
G0027_14890	COG2850	peptidyl-arginine hydroxylation
G0027_14895	COG0424	maF-like protein
G0027_14920	COG3385	transposase activity
G0027_14925	COG0697	spore germination
G0027_14965	COG3698	Phosphodiester glycosidase
G0027_14985	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0027_14985	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0027_14985	COG0506	proline dehydrogenase activity
G0027_14995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0027_15000	COG1027	Aspartate ammonia-lyase
G0027_15005	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G0027_15010	COG0583	DNA-binding transcription factor activity
G0027_15015	COG1960	acyl-CoA dehydrogenase activity
G0027_15020	COG2814	Major facilitator Superfamily
G0027_15025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0027_15040	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0027_15040	COG1902	pentaerythritol trinitrate reductase activity
G0027_15075	COG0148	phosphopyruvate hydratase activity
G0027_15090	COG0772	Belongs to the SEDS family
G0027_15105	COG2137	regulation of response to DNA damage stimulus
G0027_15115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G0027_15120	COG1011	Hydrolase
G0027_15140	COG0268	Binds directly to 16S ribosomal RNA
G0027_15145	COG0702	epimerase
G0027_15150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G0027_15165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G0027_15195	COG0316	Belongs to the HesB IscA family
G0027_15200	COG0822	iron-sulfur transferase activity
G0027_15230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0027_15285	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G0027_15305	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0027_15315	COG0133	tryptophan synthase activity
G0027_15320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0027_15320	COG0517	IMP dehydrogenase activity
G0027_15320	COG0617	tRNA 3'-terminal CCA addition
G0027_15350	COG0612	Peptidase, M16
G0027_15355	COG0552	protein localization to endoplasmic reticulum
G0027_15400	COG0693	protein deglycase activity
G0027_15410	COG1283	sodium-dependent phosphate transmembrane transporter activity
G0027_15420	COG1346	cytolysis
G0027_15430	COG0583	DNA-binding transcription factor activity
G0027_15450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G0027_15455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0027_15470	COG1629	transport
G0027_15480	COG1960	acyl-CoA dehydrogenase activity
G0027_15485	COG2207	Transcriptional regulator
G0027_15485	COG1917	Cupin 2, conserved barrel domain protein
G0027_15490	COG2814	Major facilitator Superfamily
G0027_15500	COG1271	oxidase subunit
G0027_15515	COG1525	nuclease
G0027_15570	COG1192	Involved in chromosome partitioning
G0027_15650	COG0745	RESPONSE REGULATOR receiver
G0027_15655	COG0642	Histidine kinase
G0027_15720	COG0582	viral genome integration into host DNA
G0027_15725	COG0789	Transcriptional regulator
G0027_15735	COG1230	cation diffusion facilitator family transporter
G0027_15755	COG4372	Transposase
G0027_15760	COG3657	addiction module killer protein
G0027_15765	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_15770	COG2801	Transposase and inactivated derivatives
G0027_15780	COG2801	Transposase and inactivated derivatives
G0027_15795	COG2801	Transposase and inactivated derivatives
G0027_15800	COG0488	(ABC) transporter
G0027_15805	COG3173	Aminoglycoside phosphotransferase
G0027_15865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0027_15875	COG5002	protein histidine kinase activity
G0027_15885	COG2801	Transposase and inactivated derivatives
G0027_15915	COG1660	Displays ATPase and GTPase activities
G0027_15960	COG2801	Transposase and inactivated derivatives
G0027_16015	COG2963	transposase activity
G0027_16040	COG2801	Transposase and inactivated derivatives
G0027_16055	COG2801	Transposase and inactivated derivatives
G0027_16110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0027_16185	COG1373	ATPase (AAA superfamily
G0027_16220	COG1475	DNA binding
G0027_16225	COG1192	Involved in chromosome partitioning
G0027_16260	COG2801	Transposase and inactivated derivatives
G0027_16265	COG2801	Transposase and inactivated derivatives
G0027_16280	COG2801	Transposase and inactivated derivatives
G0027_16295	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
G0027_16365	COG3188	usher protein
G0027_16385	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_16390	COG3657	addiction module killer protein
G0027_16395	COG2801	Transposase and inactivated derivatives
G0027_16435	COG3188	usher protein
G0027_16455	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0027_16460	COG3657	addiction module killer protein
G0027_16465	COG2801	Transposase and inactivated derivatives
G0027_16505	COG2076	Multidrug Resistance protein
G0027_16520	COG0488	(ABC) transporter