locus-tag	class	description
FSC05_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC05_00010	COG0592	DNA-directed DNA polymerase activity
FSC05_00020	COG0187	DNA topoisomerase II activity
FSC05_00040	COG0488	(ABC) transporter
FSC05_00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FSC05_00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSC05_00080	COG0737	Belongs to the 5'-nucleotidase family
FSC05_00110	COG2814	Major facilitator Superfamily
FSC05_00115	COG2133	pyrroloquinoline quinone binding
FSC05_00135	COG1047	Peptidyl-prolyl cis-trans
FSC05_00140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSC05_00145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSC05_00150	COG0196	riboflavin kinase activity
FSC05_00160	COG1309	transcriptional regulator
FSC05_00165	COG0675	Transposase, IS605 OrfB family
FSC05_00175	COG1116	anion transmembrane transporter activity
FSC05_00180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSC05_00185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC05_00190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_00195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_00200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSC05_00200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FSC05_00220	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_00225	COG0546	phosphoglycolate phosphatase activity
FSC05_00230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSC05_00240	COG1309	transcriptional regulator
FSC05_00245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSC05_00255	COG3023	N-Acetylmuramoyl-L-alanine amidase
FSC05_00275	COG1064	alcohol dehydrogenase
FSC05_00280	COG2818	Glycosylase
FSC05_00290	COG0739	heme binding
FSC05_00295	COG1194	a g-specific adenine glycosylase
FSC05_00310	COG5487	UPF0391 membrane protein
FSC05_00315	COG2983	Belongs to the UPF0260 family
FSC05_00320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSC05_00325	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSC05_00335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSC05_00340	COG2814	Major facilitator Superfamily
FSC05_00345	COG1335	isochorismatase
FSC05_00350	COG0385	Bile acid
FSC05_00365	COG0560	Phosphoserine phosphatase
FSC05_00365	COG3830	Belongs to the UPF0237 family
FSC05_00385	COG0753	catalase activity
FSC05_00445	COG1464	Belongs to the NlpA lipoprotein family
FSC05_00450	COG1464	Belongs to the NlpA lipoprotein family
FSC05_00455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC05_00460	COG2011	ABC-type metal ion transport system permease component
FSC05_00465	COG0534	Mate efflux family protein
FSC05_00470	COG0436	Aminotransferase
FSC05_00475	COG2733	membrane
FSC05_00490	COG2918	glutathione biosynthetic process
FSC05_00495	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FSC05_00505	COG3150	esterase
FSC05_00545	COG0471	metal ion transport
FSC05_00560	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FSC05_00565	COG4266	Belongs to the allantoicase family
FSC05_00570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_00575	COG1247	-acetyltransferase
FSC05_00615	COG0625	glutathione transferase activity
FSC05_00625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FSC05_00640	COG1393	Belongs to the ArsC family
FSC05_00645	COG0708	Exodeoxyribonuclease III
FSC05_00665	COG2801	Transposase and inactivated derivatives
FSC05_00700	COG3188	usher protein
FSC05_00720	COG0189	ligase activity
FSC05_00725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSC05_00730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC05_00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FSC05_00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSC05_00780	COG2119	membrane
FSC05_00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_00785	COG0426	domain, Protein
FSC05_00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSC05_00835	COG1902	pentaerythritol trinitrate reductase activity
FSC05_00840	COG1519	Transferase
FSC05_00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC05_00850	COG0668	transmembrane transport
FSC05_00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC05_00870	COG0431	NADPH-dependent FMN reductase
FSC05_00885	COG2205	protein histidine kinase activity
FSC05_00885	COG0784	Response regulator, receiver
FSC05_00890	COG3162	membrane
FSC05_00895	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC05_00925	COG3706	GGDEF domain
FSC05_00930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSC05_00935	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC05_00945	COG2814	Major facilitator Superfamily
FSC05_00950	COG0629	single-stranded DNA binding
FSC05_00965	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FSC05_01025	COG1785	Belongs to the alkaline phosphatase family
FSC05_01030	COG1785	Belongs to the alkaline phosphatase family
FSC05_01105	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FSC05_01110	COG0732	type I restriction modification DNA specificity domain
FSC05_01115	COG4804	nuclease activity
FSC05_01135	COG0582	viral genome integration into host DNA
FSC05_01145	COG3158	transport of potassium into the cell
FSC05_01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FSC05_01200	COG0697	spore germination
FSC05_01220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSC05_01250	COG0427	acetyl-CoA hydrolase
FSC05_01255	COG2205	protein histidine kinase activity
FSC05_01260	COG0745	RESPONSE REGULATOR receiver
FSC05_01275	COG4221	oxidoreductase activity
FSC05_01285	COG0488	(ABC) transporter
FSC05_01315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC05_01325	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSC05_01330	COG0275	rRNA processing
FSC05_01345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSC05_01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSC05_01360	COG2226	methyltransferase
FSC05_01365	COG3385	transposase activity
FSC05_01380	COG0675	Transposase, IS605 OrfB family
FSC05_01425	COG0069	glutamate synthase activity
FSC05_01425	COG0070	glutamate synthase
FSC05_01425	COG0067	glutamate synthase
FSC05_01430	COG0493	'glutamate synthase
FSC05_01440	COG1704	LemA family
FSC05_01445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FSC05_01465	COG3307	-O-antigen
FSC05_01485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC05_01490	COG1758	RNA polymerase activity
FSC05_01495	COG0194	GDP metabolic process
FSC05_01515	COG0228	four-way junction DNA binding
FSC05_01520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FSC05_01530	COG0335	large ribosomal subunit rRNA binding
FSC05_01540	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC05_01545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FSC05_01550	COG5380	lipid catabolic process
FSC05_01560	COG3547	Transposase (IS116 IS110 IS902 family)
FSC05_01570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSC05_01595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSC05_01605	COG0277	FAD linked oxidase domain protein
FSC05_01620	COG2814	Major facilitator Superfamily
FSC05_01630	COG0628	permease
FSC05_01635	COG1192	Involved in chromosome partitioning
FSC05_01660	COG2226	methyltransferase
FSC05_01680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSC05_01685	COG0254	rRNA binding
FSC05_01690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC05_01695	COG0534	Mate efflux family protein
FSC05_01705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC05_01710	COG1960	acyl-CoA dehydrogenase activity
FSC05_01730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FSC05_01755	COG1127	ABC transporter
FSC05_01760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSC05_01765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FSC05_01770	COG2854	intermembrane phospholipid transfer
FSC05_01780	COG0598	Magnesium transport protein CorA
FSC05_01795	COG1040	competence protein
FSC05_01800	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSC05_01810	COG2937	Belongs to the GPAT DAPAT family
FSC05_01815	COG1946	Acyl-CoA thioesterase
FSC05_01820	COG1301	dicarboxylic acid transport
FSC05_01840	COG1959	2 iron, 2 sulfur cluster binding
FSC05_01850	COG0433	COG0433 Predicted ATPase
FSC05_01895	COG0088	Forms part of the polypeptide exit tunnel
FSC05_01925	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSC05_01960	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSC05_01965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSC05_01975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSC05_02010	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSC05_02015	COG0202	RNA polymerase activity
FSC05_02025	COG2072	flavoprotein involved in K transport
FSC05_02030	COG1960	acyl-CoA dehydrogenase activity
FSC05_02035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FSC05_02080	COG0697	spore germination
FSC05_02090	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FSC05_02095	COG0339	signal peptide processing
FSC05_02105	COG0557	exoribonuclease II activity
FSC05_02155	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSC05_02185	COG3040	lipid binding
FSC05_02245	COG2813	Specifically methylates the guanine in position
FSC05_02245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_02250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_02255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSC05_02265	COG3128	pkhd-type hydroxylase
FSC05_02270	COG4774	siderophore transport
FSC05_02275	COG4771	TonB-dependent receptor
FSC05_02285	COG0740	serine-type endopeptidase activity
FSC05_02300	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC05_02300	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FSC05_02310	COG0280	phosphate acetyltransferase
FSC05_02310	COG0857	belongs to the CobB CobQ family
FSC05_02315	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSC05_02345	COG0793	Belongs to the peptidase S41A family
FSC05_02360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FSC05_02375	COG0084	hydrolase, TatD family'
FSC05_02380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FSC05_02385	COG3385	transposase activity
FSC05_02390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSC05_02410	COG1546	Belongs to the CinA family
FSC05_02410	COG1058	Belongs to the CinA family
FSC05_02430	COG2814	Major facilitator Superfamily
FSC05_02435	COG0697	spore germination
FSC05_02460	COG3622	Belongs to the hyi family
FSC05_02470	COG1024	Enoyl-CoA hydratase
FSC05_02475	COG2205	protein histidine kinase activity
FSC05_02475	COG5002	protein histidine kinase activity
FSC05_02475	COG0784	Response regulator, receiver
FSC05_02480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC05_02495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSC05_02515	COG1862	Preprotein translocase
FSC05_02525	COG5001	Diguanylate cyclase
FSC05_02525	COG4251	negative regulation of phosphorylation
FSC05_02525	COG3706	GGDEF domain
FSC05_02525	COG2203	Gaf domain
FSC05_02530	COG1704	LemA family
FSC05_02540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FSC05_02555	COG5002	protein histidine kinase activity
FSC05_02560	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FSC05_02580	COG0438	transferase activity, transferring glycosyl groups
FSC05_02625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSC05_02655	COG3547	Transposase (IS116 IS110 IS902 family)
FSC05_02705	COG1960	acyl-CoA dehydrogenase activity
FSC05_02710	COG1960	acyl-CoA dehydrogenase activity
FSC05_02720	COG2205	protein histidine kinase activity
FSC05_02725	COG0745	RESPONSE REGULATOR receiver
FSC05_02735	COG1113	amino acid transport
FSC05_02745	COG2315	Protein conserved in bacteria
FSC05_02750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FSC05_02770	COG2096	Adenosyltransferase
FSC05_02775	COG4206	TonB-dependent receptor
FSC05_02820	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FSC05_02825	COG0285	dihydrofolate synthase activity
FSC05_02845	COG0675	Transposase, IS605 OrfB family
FSC05_02850	COG0450	alkyl hydroperoxide reductase
FSC05_02870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSC05_02875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FSC05_02900	COG2885	chlorophyll binding
FSC05_02905	COG2199	diguanylate cyclase activity
FSC05_02965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSC05_02970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSC05_02990	COG0494	nUDIX hydrolase
FSC05_03000	COG1214	PFAM Peptidase M22, glycoprotease
FSC05_03005	COG1968	undecaprenyl-diphosphatase activity
FSC05_03025	COG4269	membrane
FSC05_03040	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FSC05_03050	COG2132	Multicopper oxidase
FSC05_03065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSC05_03080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FSC05_03080	COG0352	thiamine-phosphate diphosphorylase activity
FSC05_03080	COG0351	phosphomethylpyrimidine kinase
FSC05_03105	COG0251	oxidation-reduction process
FSC05_03110	COG1113	amino acid transport
FSC05_03130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSC05_03155	COG0456	acetyltransferase
FSC05_03165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSC05_03170	COG0492	ferredoxin-NADP+ reductase activity
FSC05_03175	COG1674	ftsk spoiiie
FSC05_03175	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSC05_03190	COG2894	cell division
FSC05_03205	COG0204	Acyl-transferase
FSC05_03210	COG2885	chlorophyll binding
FSC05_03215	COG0210	DNA helicase
FSC05_03225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSC05_03240	COG0121	glutamine amidotransferase
FSC05_03255	COG2914	Belongs to the UPF0125 (RnfH) family
FSC05_03260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_03265	COG0735	belongs to the Fur family
FSC05_03295	COG0420	3'-5' exonuclease activity
FSC05_03315	COG2050	protein possibly involved in aromatic compounds catabolism
FSC05_03320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSC05_03330	COG0582	viral genome integration into host DNA
FSC05_03355	COG1802	Transcriptional regulator
FSC05_03405	COG3177	Filamentation induced by cAMP protein fic
FSC05_03425	COG0726	polysaccharide deacetylase
FSC05_03425	COG1649	PFAM Uncharacterised BCR, COG1649
FSC05_03430	COG1215	transferase activity, transferring glycosyl groups
FSC05_03445	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FSC05_03490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC05_03495	COG0154	amidase activity
FSC05_03500	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSC05_03505	COG1077	Cell shape determining protein MreB Mrl
FSC05_03510	COG1792	Involved in formation and maintenance of cell shape
FSC05_03515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FSC05_03520	COG0424	maF-like protein
FSC05_03525	COG1530	ribonuclease E activity
FSC05_03530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSC05_03570	COG0625	glutathione transferase activity
FSC05_03580	COG0675	Transposase, IS605 OrfB family
FSC05_03595	COG1113	amino acid transport
FSC05_03600	COG2828	Protein conserved in bacteria
FSC05_03605	COG0142	geranyltranstransferase activity
FSC05_03615	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_03635	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FSC05_03645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSC05_03650	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_03655	COG0839	Belongs to the complex I subunit 6 family
FSC05_03660	COG0713	ATP synthesis coupled electron transport
FSC05_03665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC05_03670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSC05_03685	COG1278	Cold shock
FSC05_03695	COG0583	DNA-binding transcription factor activity
FSC05_03720	COG0668	transmembrane transport
FSC05_03730	COG2081	HI0933 family
FSC05_03750	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FSC05_03775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC05_03775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSC05_03780	COG0489	protein tyrosine kinase activity
FSC05_03795	COG2358	TRAP transporter, solute receptor (TAXI family
FSC05_03870	COG0442	prolyl-tRNA aminoacylation
FSC05_03910	COG0840	transmembrane signaling receptor activity
FSC05_03915	COG0643	Histidine kinase
FSC05_03915	COG2198	Histidine kinase
FSC05_03915	COG0784	Response regulator, receiver
FSC05_03930	COG5510	response to toxic substance
FSC05_03940	COG2832	Protein of unknown function (DUF454)
FSC05_03945	COG1376	ErfK ybiS ycfS ynhG family protein
FSC05_04000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FSC05_04010	COG1289	transmembrane transporter activity
FSC05_04015	COG2814	Major facilitator Superfamily
FSC05_04030	COG0786	glutamate:sodium symporter activity
FSC05_04035	COG1115	amino acid carrier protein
FSC05_04040	COG2059	Chromate
FSC05_04045	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC05_04055	COG1607	acyl-coa hydrolase
FSC05_04065	COG2814	Major facilitator Superfamily
FSC05_04070	COG0583	DNA-binding transcription factor activity
FSC05_04090	COG0523	cobalamin synthesis protein
FSC05_04095	COG4681	YaeQ
FSC05_04105	COG2203	Gaf domain
FSC05_04105	COG2199	diguanylate cyclase activity
FSC05_04135	COG0477	Major facilitator Superfamily
FSC05_04145	COG2066	Belongs to the glutaminase family
FSC05_04155	COG0306	phosphate transporter
FSC05_04195	COG4771	TonB-dependent receptor
FSC05_04220	COG4181	ATPase activity
FSC05_04225	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FSC05_04235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC05_04245	COG0583	DNA-binding transcription factor activity
FSC05_04255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_04260	COG1773	rubredoxin
FSC05_04265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSC05_04295	COG3118	belongs to the thioredoxin family
FSC05_04315	COG1253	flavin adenine dinucleotide binding
FSC05_04335	COG3015	lipoprotein NlpE involved in copper resistance
FSC05_04350	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_04370	COG0804	urea catabolic process
FSC05_04385	COG2801	Transposase and inactivated derivatives
FSC05_04400	COG0830	nickel cation binding
FSC05_04415	COG0742	ribosomal rna small subunit methyltransferase
FSC05_04420	COG0768	penicillin binding
FSC05_04445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FSC05_04450	COG2878	Part of a membrane complex involved in electron transport
FSC05_04455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSC05_04465	COG3384	dioxygenase
FSC05_04475	COG2234	aminopeptidase activity
FSC05_04490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FSC05_04505	COG3328	transposase activity
FSC05_04515	COG0675	Transposase, IS605 OrfB family
FSC05_04530	COG2186	Transcriptional regulator
FSC05_04540	COG0277	FAD linked oxidase domain protein
FSC05_04570	COG3079	Belongs to the UPF0149 family
FSC05_04575	COG0006	proline dipeptidase activity
FSC05_04585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_04590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FSC05_04625	COG2816	NAD+ diphosphatase activity
FSC05_04640	COG0741	lytic transglycosylase activity
FSC05_04640	COG1388	LysM domain
FSC05_04645	COG4166	transmembrane transport
FSC05_04650	COG4174	ABC transporter (Permease)
FSC05_04655	COG4239	(ABC) transporter, permease
FSC05_04660	COG4172	Belongs to the ABC transporter superfamily
FSC05_04690	COG0833	amino acid
FSC05_04710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FSC05_04715	COG0418	dihydroorotase activity
FSC05_04720	COG3706	GGDEF domain
FSC05_04720	COG5001	Diguanylate cyclase
FSC05_04720	COG2203	Gaf domain
FSC05_04720	COG4251	negative regulation of phosphorylation
FSC05_04740	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_04740	COG1902	pentaerythritol trinitrate reductase activity
FSC05_04845	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FSC05_04865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FSC05_04870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSC05_04875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSC05_04880	COG3385	transposase activity
FSC05_04905	COG1960	acyl-CoA dehydrogenase activity
FSC05_04910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC05_04920	COG2175	clavaminate synthase activity
FSC05_04940	COG0052	Belongs to the universal ribosomal protein uS2 family
FSC05_04965	COG2951	lytic endotransglycosylase activity
FSC05_04980	COG0842	Transport permease protein
FSC05_04985	COG1131	(ABC) transporter
FSC05_05045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC05_05065	COG3634	alkyl hydroperoxide reductase activity
FSC05_05070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_05085	COG0640	Transcriptional regulator
FSC05_05095	COG0798	PFAM Bile acid sodium symporter
FSC05_05100	COG0431	NADPH-dependent FMN reductase
FSC05_05105	COG0789	Transcriptional regulator
FSC05_05120	COG1720	tRNA m6t6A37 methyltransferase activity
FSC05_05130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSC05_05140	COG0745	RESPONSE REGULATOR receiver
FSC05_05145	COG0642	Histidine kinase
FSC05_05165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSC05_05170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSC05_05175	COG3139	Protein of unknown function (DUF1315)
FSC05_05185	COG1301	dicarboxylic acid transport
FSC05_05190	COG1960	acyl-CoA dehydrogenase activity
FSC05_05195	COG0693	protein deglycase activity
FSC05_05205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSC05_05210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSC05_05235	COG1047	Peptidyl-prolyl cis-trans
FSC05_05240	COG1252	NADH dehydrogenase
FSC05_05245	COG1686	Belongs to the peptidase S11 family
FSC05_05260	COG1187	pseudouridine synthase activity
FSC05_05270	COG0739	heme binding
FSC05_05280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_05290	COG0612	Peptidase, M16
FSC05_05325	COG0352	thiamine-phosphate diphosphorylase activity
FSC05_05365	COG0596	Alpha beta hydrolase
FSC05_05370	COG1309	transcriptional regulator
FSC05_05410	COG1278	Cold shock
FSC05_05425	COG2070	2-Nitropropane dioxygenase
FSC05_05450	COG2391	methyltransferase activity
FSC05_05460	COG3634	alkyl hydroperoxide reductase activity
FSC05_05490	COG1643	Atp-dependent helicase
FSC05_05515	COG0517	IMP dehydrogenase activity
FSC05_05515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FSC05_05520	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FSC05_05530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FSC05_05535	COG1137	ATPase activity
FSC05_05570	COG4122	O-methyltransferase activity
FSC05_05580	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FSC05_05625	COG2011	ABC-type metal ion transport system permease component
FSC05_05630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FSC05_05650	COG0138	bifunctional purine biosynthesis protein purh
FSC05_05655	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FSC05_05695	COG2308	Evidence 4 Homologs of previously reported genes of
FSC05_05705	COG1305	Transglutaminase-like
FSC05_05720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSC05_05735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSC05_05740	COG0360	Binds together with S18 to 16S ribosomal RNA
FSC05_05750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FSC05_05755	COG1845	cytochrome c oxidase, subunit III
FSC05_05760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSC05_05765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSC05_05790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSC05_05805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSC05_05815	COG3781	membrane
FSC05_05835	COG1960	acyl-CoA dehydrogenase activity
FSC05_05840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSC05_05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSC05_05865	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSC05_05880	COG0477	Major facilitator Superfamily
FSC05_05925	COG0786	glutamate:sodium symporter activity
FSC05_05960	COG0308	aminopeptidase N
FSC05_05970	COG0589	response to stress
FSC05_05975	COG0589	response to stress
FSC05_05985	COG3135	benzoate transporter
FSC05_05995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSC05_06010	COG0183	Belongs to the thiolase family
FSC05_06020	COG2030	dehydratase
FSC05_06035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FSC05_06040	COG0824	Thioesterase
FSC05_06045	COG1454	alcohol dehydrogenase
FSC05_06050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSC05_06070	COG0069	glutamate synthase activity
FSC05_06075	COG2197	response regulator
FSC05_06080	COG4585	Histidine kinase
FSC05_06085	COG2850	peptidyl-arginine hydroxylation
FSC05_06090	COG0424	maF-like protein
FSC05_06115	COG0697	spore germination
FSC05_06155	COG3698	Phosphodiester glycosidase
FSC05_06175	COG0506	proline dehydrogenase activity
FSC05_06175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC05_06175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FSC05_06185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_06190	COG1027	Aspartate ammonia-lyase
FSC05_06195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSC05_06200	COG0583	DNA-binding transcription factor activity
FSC05_06205	COG1960	acyl-CoA dehydrogenase activity
FSC05_06210	COG2814	Major facilitator Superfamily
FSC05_06215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSC05_06230	COG1902	pentaerythritol trinitrate reductase activity
FSC05_06230	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_06260	COG0148	phosphopyruvate hydratase activity
FSC05_06275	COG0772	Belongs to the SEDS family
FSC05_06290	COG2137	regulation of response to DNA damage stimulus
FSC05_06300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSC05_06305	COG1011	Hydrolase
FSC05_06325	COG0268	Binds directly to 16S ribosomal RNA
FSC05_06330	COG0702	epimerase
FSC05_06335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSC05_06350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FSC05_06380	COG0316	Belongs to the HesB IscA family
FSC05_06385	COG0822	iron-sulfur transferase activity
FSC05_06415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_06470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSC05_06490	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC05_06500	COG0133	tryptophan synthase activity
FSC05_06505	COG0617	tRNA 3'-terminal CCA addition
FSC05_06505	COG0517	IMP dehydrogenase activity
FSC05_06505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC05_06535	COG0612	Peptidase, M16
FSC05_06540	COG0552	protein localization to endoplasmic reticulum
FSC05_06585	COG0693	protein deglycase activity
FSC05_06595	COG1283	sodium-dependent phosphate transmembrane transporter activity
FSC05_06605	COG1346	cytolysis
FSC05_06615	COG0583	DNA-binding transcription factor activity
FSC05_06635	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FSC05_06640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC05_06665	COG1960	acyl-CoA dehydrogenase activity
FSC05_06670	COG2207	Transcriptional regulator
FSC05_06675	COG2814	Major facilitator Superfamily
FSC05_06685	COG1271	oxidase subunit
FSC05_06690	COG1294	oxidase, subunit
FSC05_06700	COG1525	nuclease
FSC05_06750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC05_06755	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSC05_06770	COG1113	amino acid transport
FSC05_06780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC05_06790	COG2814	Major facilitator Superfamily
FSC05_06810	COG1132	(ABC) transporter
FSC05_06825	COG0668	transmembrane transport
FSC05_06830	COG3122	Protein conserved in bacteria
FSC05_06850	COG0640	Transcriptional regulator
FSC05_06855	COG2937	Belongs to the GPAT DAPAT family
FSC05_06860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSC05_06865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSC05_06865	COG1116	anion transmembrane transporter activity
FSC05_06875	COG2223	nitrite transmembrane transporter activity
FSC05_06880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_06880	COG2146	nitrite reductase [NAD(P)H] activity
FSC05_06885	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_06890	COG0243	molybdopterin cofactor binding
FSC05_06900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSC05_06915	COG0315	cyclic pyranopterin monophosphate synthase activity
FSC05_06915	COG0521	Mo-molybdopterin cofactor biosynthetic process
FSC05_06920	COG0303	'Molybdopterin
FSC05_06925	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSC05_06930	COG4149	molybdate abc transporter
FSC05_06935	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FSC05_06960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_06965	COG0183	Belongs to the thiolase family
FSC05_06970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_06975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC05_06980	COG3135	benzoate transporter
FSC05_07020	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_07030	COG2223	nitrite transmembrane transporter activity
FSC05_07040	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FSC05_07045	COG2116	formate transmembrane transporter activity
FSC05_07050	COG0515	serine threonine protein kinase
FSC05_07065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_07100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FSC05_07105	COG1309	transcriptional regulator
FSC05_07110	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_07130	COG0745	RESPONSE REGULATOR receiver
FSC05_07140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSC05_07170	COG2885	chlorophyll binding
FSC05_07180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FSC05_07185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSC05_07190	COG0730	response to heat
FSC05_07215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSC05_07220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSC05_07225	COG0022	dehydrogenase e1 component
FSC05_07230	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSC05_07235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC05_07245	COG1063	alcohol dehydrogenase
FSC05_07250	COG4628	conserved protein (DUF2132)
FSC05_07260	COG2801	Transposase and inactivated derivatives
FSC05_07375	COG0596	Alpha beta hydrolase
FSC05_07410	COG0511	ligase activity, forming carbon-carbon bonds
FSC05_07415	COG0439	Biotin carboxylase
FSC05_07430	COG2814	Major facilitator Superfamily
FSC05_07465	COG1546	Belongs to the CinA family
FSC05_07465	COG1058	Belongs to the CinA family
FSC05_07475	COG0372	Belongs to the citrate synthase family
FSC05_07495	COG0477	Major facilitator Superfamily
FSC05_07510	COG0542	response to heat
FSC05_07515	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSC05_07535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FSC05_07545	COG0569	domain protein
FSC05_07550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FSC05_07570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSC05_07580	COG1585	Membrane protein implicated in regulation of membrane protease activity
FSC05_07595	COG1294	oxidase, subunit
FSC05_07600	COG4890	Cyd operon protein YbgT
FSC05_07640	COG1960	acyl-CoA dehydrogenase activity
FSC05_07645	COG1960	acyl-CoA dehydrogenase activity
FSC05_07655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FSC05_07660	COG2207	Transcriptional regulator
FSC05_07665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC05_07670	COG0730	response to heat
FSC05_07675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FSC05_07705	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FSC05_07725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_07740	COG0575	Belongs to the CDS family
FSC05_07745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSC05_07750	COG0233	cytoplasmic translational termination
FSC05_07765	COG3852	Histidine kinase
FSC05_07770	COG2204	response regulator
FSC05_07780	COG0583	DNA-binding transcription factor activity
FSC05_07810	COG1253	flavin adenine dinucleotide binding
FSC05_07830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FSC05_07835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FSC05_07850	COG2431	L-lysine efflux transmembrane transporter activity
FSC05_07855	COG0284	orotidine-5'-phosphate decarboxylase activity
FSC05_07865	COG0776	regulation of translation
FSC05_07895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FSC05_07930	COG0084	hydrolase, TatD family'
FSC05_07950	COG1663	tetraacyldisaccharide 4'-kinase activity
FSC05_07955	COG1132	(ABC) transporter
FSC05_07965	COG0811	peptide transport
FSC05_07970	COG1475	DNA binding
FSC05_07975	COG1192	Involved in chromosome partitioning
FSC05_07985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSC05_07990	COG3178	'Phosphotransferase
FSC05_08000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_08005	COG1923	regulation of RNA biosynthetic process
FSC05_08015	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FSC05_08020	COG0802	atpase or kinase
FSC05_08045	COG2707	UPF0756 membrane protein
FSC05_08055	COG0583	DNA-binding transcription factor activity
FSC05_08060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_08090	COG0519	Catalyzes the synthesis of GMP from XMP
FSC05_08090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC05_08095	COG2353	YceI-like domain
FSC05_08105	COG3385	transposase activity
FSC05_08110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FSC05_08115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FSC05_08150	COG1254	Belongs to the acylphosphatase family
FSC05_08155	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSC05_08155	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSC05_08160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FSC05_08180	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_08190	COG3327	negative regulation of DNA-templated transcription, initiation
FSC05_08195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FSC05_08200	COG0183	Belongs to the thiolase family
FSC05_08205	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_08210	COG1024	Enoyl-CoA hydratase
FSC05_08215	COG1024	Enoyl-CoA hydratase
FSC05_08220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FSC05_08225	COG2151	metal-sulfur cluster biosynthetic enzyme
FSC05_08230	COG3396	Phenylacetate-CoA oxygenase
FSC05_08235	COG3460	Phenylacetate-CoA oxygenase
FSC05_08240	COG3396	Phenylacetate-CoA oxygenase
FSC05_08245	COG2030	dehydratase
FSC05_08245	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_08250	COG2814	Major facilitator Superfamily
FSC05_08255	COG0783	Belongs to the Dps family
FSC05_08285	COG2801	Transposase and inactivated derivatives
FSC05_08295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSC05_08300	COG0183	Belongs to the thiolase family
FSC05_08310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_08315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FSC05_08320	COG1414	Transcriptional regulator
FSC05_08330	COG4774	siderophore transport
FSC05_08345	COG0579	oxidoreductase
FSC05_08390	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSC05_08425	COG0642	Histidine kinase
FSC05_08440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FSC05_08465	COG2816	NAD+ diphosphatase activity
FSC05_08470	COG3046	protein related to deoxyribodipyrimidine photolyase
FSC05_08485	COG2351	hydroxyisourate hydrolase activity
FSC05_08505	COG1136	(ABC) transporter
FSC05_08515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_08540	COG0204	Acyl-transferase
FSC05_08565	COG0012	GTP binding
FSC05_08575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FSC05_08590	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FSC05_08600	COG0386	Belongs to the glutathione peroxidase family
FSC05_08605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSC05_08610	COG0436	Aminotransferase
FSC05_08615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSC05_08615	COG2755	lipolytic protein G-D-S-L family
FSC05_08655	COG0515	serine threonine protein kinase
FSC05_08655	COG2815	serine threonine protein kinase
FSC05_08685	COG1610	YqeY-like protein
FSC05_08700	COG4783	chaperone-mediated protein folding
FSC05_08765	COG0513	Belongs to the DEAD box helicase family
FSC05_08785	COG2363	Small membrane protein
FSC05_08805	COG0659	secondary active sulfate transmembrane transporter activity
FSC05_08815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FSC05_08835	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_08840	COG1309	transcriptional regulator
FSC05_08845	COG1960	acyl-CoA dehydrogenase activity
FSC05_08850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSC05_08855	COG1024	Enoyl-CoA hydratase
FSC05_08860	COG4770	biotin carboxylase activity
FSC05_08875	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSC05_08890	COG0540	Belongs to the ATCase OTCase family
FSC05_08910	COG1765	OsmC-like protein
FSC05_08920	COG0667	Aldo Keto reductase
FSC05_08935	COG0501	Belongs to the peptidase M48B family
FSC05_08940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSC05_08955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSC05_08965	COG0527	aspartate kinase activity
FSC05_08975	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FSC05_08985	COG1215	transferase activity, transferring glycosyl groups
FSC05_08995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSC05_09000	COG2252	PERMEase
FSC05_09030	COG0714	Associated with various cellular activities
FSC05_09035	COG2879	small protein
FSC05_09040	COG1966	Carbon starvation protein
FSC05_09045	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSC05_09050	COG1509	lysine 2,3-aminomutase activity
FSC05_09085	COG1067	ATP-dependent peptidase activity
FSC05_09090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FSC05_09095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSC05_09100	COG0583	DNA-binding transcription factor activity
FSC05_09110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FSC05_09125	COG1686	Belongs to the peptidase S11 family
FSC05_09130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FSC05_09165	COG0616	signal peptide processing
FSC05_09170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSC05_09180	COG0573	inorganic phosphate transmembrane transporter activity
FSC05_09190	COG0076	glutamate decarboxylase activity
FSC05_09195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FSC05_09250	COG1570	exodeoxyribonuclease VII activity
FSC05_09260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_09265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC05_09270	COG2194	sulfuric ester hydrolase activity
FSC05_09275	COG0745	RESPONSE REGULATOR receiver
FSC05_09280	COG0642	Histidine kinase
FSC05_09320	COG3646	Phage regulatory protein
FSC05_09335	COG0582	viral genome integration into host DNA
FSC05_09340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FSC05_09350	COG2814	Major facilitator Superfamily
FSC05_09355	COG1733	regulation of RNA biosynthetic process
FSC05_09360	COG0702	epimerase
FSC05_09390	COG0556	nucleotide-excision repair
FSC05_09410	COG0436	Aminotransferase
FSC05_09440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FSC05_09445	COG1381	Involved in DNA repair and RecF pathway recombination
FSC05_09455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSC05_09460	COG0571	ribonuclease III activity
FSC05_09470	COG0681	Belongs to the peptidase S26 family
FSC05_09485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSC05_09495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSC05_09510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSC05_09535	COG4208	sulfate ABC transporter
FSC05_09540	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FSC05_09545	COG0583	DNA-binding transcription factor activity
FSC05_09565	COG0602	queuosine metabolic process
FSC05_09570	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FSC05_09580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSC05_09585	COG2353	YceI-like domain
FSC05_09590	COG1051	belongs to the nudix hydrolase family
FSC05_09590	COG1056	cytidyltransferase-related domain
FSC05_09595	COG1024	Enoyl-CoA hydratase
FSC05_09600	COG0778	Nitroreductase
FSC05_09615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSC05_09615	COG0047	phosphoribosylformylglycinamidine synthase activity
FSC05_09635	COG2255	four-way junction helicase activity
FSC05_09645	COG0824	Thioesterase
FSC05_09665	COG0823	Involved in the tonB-independent uptake of proteins
FSC05_09685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC05_09715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSC05_09720	COG0628	permease
FSC05_09725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSC05_09730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FSC05_09750	COG0658	competence protein
FSC05_09750	COG2333	competence protein COMEC
FSC05_09755	COG1136	(ABC) transporter
FSC05_09760	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSC05_09775	COG1671	Belongs to the UPF0178 family
FSC05_09815	COG1280	lysine exporter protein (LysE YggA)
FSC05_09820	COG1522	sequence-specific DNA binding
FSC05_09830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSC05_09845	COG0019	diaminopimelate decarboxylase activity
FSC05_09855	COG1113	amino acid transport
FSC05_09860	COG1115	amino acid carrier protein
FSC05_09880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FSC05_09885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FSC05_09920	COG0583	DNA-binding transcription factor activity
FSC05_09930	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FSC05_09940	COG0174	glutamine synthetase
FSC05_09945	COG0512	Glutamine amidotransferase of anthranilate synthase
FSC05_09975	COG3706	GGDEF domain
FSC05_09990	COG3739	integral membrane protein
FSC05_09995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FSC05_10005	COG1741	Belongs to the pirin family
FSC05_10010	COG3842	ATPase activity
FSC05_10015	COG1840	ABC-type Fe3 transport system, periplasmic component
FSC05_10045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FSC05_10050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FSC05_10060	COG0037	tRNA processing
FSC05_10065	COG0741	lytic transglycosylase activity
FSC05_10065	COG1196	nuclear chromosome segregation
FSC05_10065	COG0739	heme binding
FSC05_10070	COG0501	Belongs to the peptidase M48B family
FSC05_10080	COG2239	Acts as a magnesium transporter
FSC05_10115	COG1597	lipid kinase activity
FSC05_10135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSC05_10180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSC05_10190	COG1534	Rna-binding protein
FSC05_10205	COG0505	Belongs to the CarA family
FSC05_10220	COG0415	Belongs to the DNA photolyase family
FSC05_10225	COG0110	maltose O-acetyltransferase activity
FSC05_10230	COG0589	response to stress
FSC05_10240	COG2321	neutral zinc metallopeptidase
FSC05_10245	COG2354	Protein conserved in bacteria
FSC05_10260	COG2268	Band 7 protein
FSC05_10270	COG1215	transferase activity, transferring glycosyl groups
FSC05_10285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSC05_10295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSC05_10310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSC05_10315	COG1053	succinate dehydrogenase
FSC05_10320	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FSC05_10335	COG2072	flavoprotein involved in K transport
FSC05_10340	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_10350	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FSC05_10365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC05_10365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FSC05_10395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_10405	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSC05_10420	COG0564	pseudouridine synthase activity
FSC05_10430	COG0358	DNA primase activity
FSC05_10445	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FSC05_10475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSC05_10515	COG0586	Pfam SNARE associated Golgi protein
FSC05_10540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSC05_10550	COG0321	lipoyl(octanoyl) transferase activity
FSC05_10570	COG0531	amino acid
FSC05_10575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FSC05_10580	COG1648	precorrin-2 dehydrogenase activity
FSC05_10580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSC05_10585	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSC05_10595	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FSC05_10620	COG0671	phosphoesterase, PA-phosphatase related
FSC05_10625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_10635	COG1538	Outer membrane efflux protein
FSC05_10640	COG0393	Putative heavy-metal-binding
FSC05_10645	COG0393	Putative heavy-metal-binding
FSC05_10660	COG0525	valine-tRNA ligase activity
FSC05_10675	COG2852	Protein conserved in bacteria
FSC05_10690	COG2323	membrane
FSC05_10700	COG0765	amino acid transport
FSC05_10705	COG0765	amino acid transport
FSC05_10710	COG1126	abc transporter atp-binding protein
FSC05_10715	COG3338	carbonate dehydratase activity
FSC05_10730	COG1752	Esterase of the alpha-beta hydrolase superfamily
FSC05_10745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FSC05_10750	COG2205	protein histidine kinase activity
FSC05_10755	COG0745	RESPONSE REGULATOR receiver
FSC05_10770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSC05_10775	COG1652	LysM domain
FSC05_10785	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_10800	COG1399	metal-binding, possibly nucleic acid-binding protein
FSC05_10805	COG3101	peptidyl-lysine hydroxylation
FSC05_10810	COG0009	L-threonylcarbamoyladenylate synthase
FSC05_10820	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSC05_10825	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSC05_10840	COG4106	trans-aconitate 2-methyltransferase activity
FSC05_10855	COG2226	methyltransferase
FSC05_10855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSC05_10855	COG0596	Alpha beta hydrolase
FSC05_10860	COG2193	ferroxidase activity
FSC05_10865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSC05_10870	COG3115	cell septum assembly
FSC05_10875	COG1196	nuclear chromosome segregation
FSC05_10885	COG0730	response to heat
FSC05_10905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSC05_10920	COG2801	Transposase and inactivated derivatives
FSC05_10930	COG2801	Transposase and inactivated derivatives
FSC05_10940	COG2801	Transposase and inactivated derivatives
FSC05_10970	COG0628	permease
FSC05_10980	COG2824	Alkylphosphonate utilization operon protein PhnA
FSC05_10985	COG3189	MarR family transcriptional regulator
FSC05_11000	COG0564	pseudouridine synthase activity
FSC05_11045	COG0354	folic acid binding
FSC05_11075	COG0363	glucosamine-6-phosphate deaminase activity
FSC05_11085	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FSC05_11090	COG1877	trehalose-phosphatase activity
FSC05_11100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSC05_11105	COG1970	mechanosensitive ion channel activity
FSC05_11115	COG2233	PERMEase
FSC05_11125	COG0833	amino acid
FSC05_11145	COG0183	Belongs to the thiolase family
FSC05_11160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSC05_11170	COG2207	Transcriptional regulator
FSC05_11175	COG0183	Belongs to the thiolase family
FSC05_11180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_11180	COG1024	Enoyl-CoA hydratase
FSC05_11205	COG1272	protein, Hemolysin III
FSC05_11210	COG0477	Major facilitator Superfamily
FSC05_11220	COG1408	metallophosphoesterase
FSC05_11225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSC05_11235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSC05_11270	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FSC05_11275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSC05_11280	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FSC05_11290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSC05_11295	COG0625	glutathione transferase activity
FSC05_11300	COG2969	positive regulation of protein catabolic process
FSC05_11355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSC05_11400	COG0037	tRNA processing
FSC05_11410	COG0248	Ppx GppA phosphatase
FSC05_11435	COG0072	phenylalanine-tRNA ligase activity
FSC05_11470	COG1238	metal cluster binding
FSC05_11475	COG0625	glutathione transferase activity
FSC05_11500	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_11505	COG3028	Belongs to the UPF0307 family
FSC05_11515	COG1660	Displays ATPase and GTPase activities
FSC05_11530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSC05_11535	COG0617	tRNA 3'-terminal CCA addition
FSC05_11540	COG1555	photosystem II stabilization
FSC05_11545	COG3956	TIGRFAM MazG family protein
FSC05_11560	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FSC05_11570	COG0124	histidyl-tRNA synthetase
FSC05_11600	COG2975	iron-sulfur cluster assembly
FSC05_11640	COG0440	acetolactate synthase activity
FSC05_11645	COG0028	Belongs to the TPP enzyme family
FSC05_11670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_11675	COG0577	efflux transmembrane transporter activity
FSC05_11675	COG1136	(ABC) transporter
FSC05_11710	COG3209	COG3209 Rhs family protein
FSC05_11730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FSC05_11735	COG1162	GTPase activity
FSC05_11745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FSC05_11755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FSC05_11765	COG3781	membrane
FSC05_11780	COG2350	Protein conserved in bacteria
FSC05_11800	COG1666	GTP binding
FSC05_11810	COG1607	acyl-coa hydrolase
FSC05_11870	COG1183	phosphatidylcholine synthase activity
FSC05_11875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FSC05_11915	COG1196	nuclear chromosome segregation
FSC05_11915	COG0739	heme binding
FSC05_11915	COG0741	lytic transglycosylase activity
FSC05_11925	COG1702	phosphate starvation-inducible protein PhoH
FSC05_11975	COG1295	ribonuclease BN
FSC05_12005	COG0788	formyltetrahydrofolate deformylase activity
FSC05_12030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FSC05_12030	COG4651	solute:proton antiporter activity
FSC05_12045	COG0724	RNA recognition motif
FSC05_12050	COG0210	DNA helicase
FSC05_12060	COG1929	Belongs to the glycerate kinase type-1 family
FSC05_12090	COG2900	Belongs to the SlyX family
FSC05_12100	COG1560	Kdo2-lipid A biosynthetic process
FSC05_12155	COG0473	3-isopropylmalate dehydrogenase activity
FSC05_12170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSC05_12185	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSC05_12200	COG0494	nUDIX hydrolase
FSC05_12220	COG1960	acyl-CoA dehydrogenase activity
FSC05_12245	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSC05_12250	COG3384	dioxygenase
FSC05_12255	COG1028	Short-chain dehydrogenase reductase Sdr
FSC05_12270	COG4638	Rieske (2fe-2S)
FSC05_12275	COG0583	DNA-binding transcription factor activity
FSC05_12300	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FSC05_12305	COG3971	2-oxopent-4-enoate hydratase activity
FSC05_12310	COG0546	phosphoglycolate phosphatase activity
FSC05_12325	COG1530	ribonuclease E activity
FSC05_12330	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_12355	COG1983	PspC domain protein
FSC05_12360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSC05_12360	COG0617	tRNA 3'-terminal CCA addition
FSC05_12360	COG0517	IMP dehydrogenase activity
FSC05_12370	COG0751	glycine-tRNA ligase activity
FSC05_12400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSC05_12425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSC05_12425	COG0493	'glutamate synthase
FSC05_12435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FSC05_12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSC05_12460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSC05_12470	COG0644	oxidoreductase
FSC05_12470	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSC05_12475	COG3293	Transposase
FSC05_12510	COG2801	Transposase and inactivated derivatives
FSC05_12535	COG3501	Rhs element vgr protein
FSC05_12540	COG0425	Belongs to the sulfur carrier protein TusA family
FSC05_12545	COG4535	Mg2 and Co2 transporter CorC
FSC05_12550	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FSC05_12570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSC05_12580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FSC05_12590	COG0789	Transcriptional regulator
FSC05_12595	COG2841	Protein conserved in bacteria
FSC05_12610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FSC05_12615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_12620	COG1074	ATP-dependent DNA helicase activity
FSC05_12625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FSC05_12655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSC05_12665	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSC05_12680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FSC05_12680	COG2111	Na H antiporter
FSC05_12685	COG1006	Multisubunit Na H antiporter MnhC subunit
FSC05_12690	COG0651	ATP synthesis coupled electron transport
FSC05_12700	COG2212	antiporter activity
FSC05_12710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSC05_12720	COG0195	Participates in both transcription termination and antitermination
FSC05_12725	COG0779	Required for maturation of 30S ribosomal subunits
FSC05_12775	COG0237	dephospho-CoA kinase activity
FSC05_12785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSC05_12790	COG3123	guanosine phosphorylase activity
FSC05_12795	COG0497	DNA recombination
FSC05_12805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSC05_12820	COG1132	(ABC) transporter
FSC05_12825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSC05_12855	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSC05_12855	COG1024	Enoyl-CoA hydratase
FSC05_12865	COG2233	PERMEase
FSC05_12875	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FSC05_12900	COG0326	Molecular chaperone. Has ATPase activity
FSC05_12915	COG2056	Na+-H+ antiporter family
FSC05_12935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSC05_12940	COG0085	RNA polymerase activity
FSC05_12955	COG0081	regulation of translation
FSC05_13040	COG0824	Thioesterase
FSC05_13060	COG0181	hydroxymethylbilane synthase activity
FSC05_13070	COG3275	phosphorelay sensor kinase activity
FSC05_13105	COG0494	nUDIX hydrolase
FSC05_13110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FSC05_13115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSC05_13120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSC05_13130	COG0772	Belongs to the SEDS family
FSC05_13135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSC05_13155	COG4974	Belongs to the 'phage' integrase family
FSC05_13170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSC05_13180	COG2197	response regulator
FSC05_13195	COG0793	Belongs to the peptidase S41A family
FSC05_13200	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSC05_13205	COG0795	lipopolysaccharide-transporting ATPase activity
FSC05_13210	COG0795	lipopolysaccharide-transporting ATPase activity
FSC05_13235	COG0586	Pfam SNARE associated Golgi protein
FSC05_13250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC05_13250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FSC05_13260	COG0004	ammonium transporteR
FSC05_13265	COG0347	Belongs to the P(II) protein family
FSC05_13275	COG0606	chelatase, subunit chli
FSC05_13290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FSC05_13305	COG0318	PFAM AMP-dependent synthetase and ligase
FSC05_13315	COG0477	Major facilitator Superfamily
FSC05_13320	COG2860	membrane
FSC05_13330	COG1253	flavin adenine dinucleotide binding
FSC05_13350	COG2814	Major facilitator Superfamily
FSC05_13365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_13390	COG2814	Major facilitator Superfamily
FSC05_13440	COG0758	DNA mediated transformation
FSC05_13455	COG0697	spore germination
FSC05_13460	COG0386	Belongs to the glutathione peroxidase family
FSC05_13485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSC05_13535	COG1121	(ABC) transporter
FSC05_13540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSC05_13550	COG2837	iron assimilation
FSC05_13570	COG3501	Rhs element vgr protein
FSC05_13575	COG0281	malic enzyme
FSC05_13615	COG1715	Restriction endonuclease
FSC05_13620	COG2826	transposase and inactivated derivatives, IS30 family
FSC05_13625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSC05_13625	COG0519	Catalyzes the synthesis of GMP from XMP
FSC05_13630	COG2259	Doxx family
FSC05_13635	COG0586	Pfam SNARE associated Golgi protein
FSC05_13650	COG1192	Involved in chromosome partitioning
FSC05_13660	COG0271	Belongs to the BolA IbaG family
FSC05_13695	COG3756	Protein conserved in bacteria
FSC05_13715	COG3586	endonuclease activity
FSC05_13765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSC05_13770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSC05_13785	COG1570	exodeoxyribonuclease VII activity
FSC05_13850	COG1570	exodeoxyribonuclease VII activity
FSC05_13880	COG2801	Transposase and inactivated derivatives
FSC05_13890	COG2801	Transposase and inactivated derivatives
FSC05_13915	COG2801	Transposase and inactivated derivatives
FSC05_13960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSC05_13975	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FSC05_13985	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSC05_14035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FSC05_14050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FSC05_14060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSC05_14070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSC05_14075	COG0438	transferase activity, transferring glycosyl groups
FSC05_14085	COG0438	transferase activity, transferring glycosyl groups
FSC05_14090	COG1215	transferase activity, transferring glycosyl groups
FSC05_14100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FSC05_14100	COG1215	transferase activity, transferring glycosyl groups
FSC05_14105	COG0438	transferase activity, transferring glycosyl groups
FSC05_14110	COG1442	glycosyl transferase family 8
FSC05_14110	COG1216	Glycosyl transferase, family 2
FSC05_14115	COG5039	Polysaccharide pyruvyl transferase
FSC05_14180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FSC05_14185	COG1309	transcriptional regulator
FSC05_14195	COG2233	PERMEase
FSC05_14210	COG0129	dihydroxy-acid dehydratase activity
FSC05_14225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSC05_14230	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSC05_14240	COG0733	neurotransmitter:sodium symporter activity
FSC05_14245	COG1012	belongs to the aldehyde dehydrogenase family
FSC05_14265	COG2814	Major facilitator Superfamily
FSC05_14295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSC05_14340	COG2951	lytic endotransglycosylase activity
FSC05_14350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FSC05_14370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSC05_14390	COG2388	GCN5-related N-acetyl-transferase
FSC05_14400	COG0861	Integral membrane protein TerC family
FSC05_14405	COG0402	S-adenosylhomocysteine deaminase activity
FSC05_14420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSC05_14425	COG1230	cation diffusion facilitator family transporter
FSC05_14450	COG0706	membrane insertase activity
FSC05_14455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSC05_14460	COG0594	ribonuclease P activity
FSC05_14510	COG1192	Involved in chromosome partitioning
FSC05_14625	COG0582	viral genome integration into host DNA
FSC05_14640	COG1230	cation diffusion facilitator family transporter
FSC05_14675	COG1683	Conserved Protein
FSC05_14730	COG4974	Belongs to the 'phage' integrase family
FSC05_14820	COG1373	ATPase (AAA superfamily
FSC05_14905	COG0673	inositol 2-dehydrogenase activity
FSC05_14925	COG2826	transposase and inactivated derivatives, IS30 family
FSC05_14945	COG1660	Displays ATPase and GTPase activities
FSC05_15010	COG2801	Transposase and inactivated derivatives
FSC05_15015	COG2801	Transposase and inactivated derivatives
FSC05_15040	COG2963	transposase activity
FSC05_15180	COG2801	Transposase and inactivated derivatives
FSC05_15190	COG2801	Transposase and inactivated derivatives
FSC05_15205	COG3657	addiction module killer protein
FSC05_15210	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSC05_15225	COG3188	usher protein
FSC05_15245	COG2801	Transposase and inactivated derivatives
FSC05_15260	COG0270	DNA (cytosine-5-)-methyltransferase activity
FSC05_15355	COG0488	(ABC) transporter
FSC05_15360	COG0300	oxidoreductase activity