locus-tag	class	description
G0030_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0030_00010	COG0592	DNA-directed DNA polymerase activity
G0030_00020	COG0187	DNA topoisomerase II activity
G0030_00025	COG1063	alcohol dehydrogenase
G0030_00030	COG0488	(ABC) transporter
G0030_00055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G0030_00060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G0030_00110	COG2814	Major facilitator Superfamily
G0030_00115	COG2133	pyrroloquinoline quinone binding
G0030_00125	COG1047	Peptidyl-prolyl cis-trans
G0030_00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G0030_00135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G0030_00140	COG0196	riboflavin kinase activity
G0030_00150	COG1309	transcriptional regulator
G0030_00155	COG1116	anion transmembrane transporter activity
G0030_00160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G0030_00165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0030_00170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0030_00175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0030_00180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G0030_00180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G0030_00200	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_00205	COG0546	phosphoglycolate phosphatase activity
G0030_00210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G0030_00220	COG1309	transcriptional regulator
G0030_00225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G0030_00235	COG3023	N-Acetylmuramoyl-L-alanine amidase
G0030_00255	COG1064	alcohol dehydrogenase
G0030_00260	COG2818	Glycosylase
G0030_00270	COG0739	heme binding
G0030_00275	COG1194	a g-specific adenine glycosylase
G0030_00290	COG5487	UPF0391 membrane protein
G0030_00295	COG2983	Belongs to the UPF0260 family
G0030_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G0030_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G0030_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G0030_00320	COG2814	Major facilitator Superfamily
G0030_00325	COG1335	isochorismatase
G0030_00330	COG0385	Bile acid
G0030_00345	COG0560	Phosphoserine phosphatase
G0030_00345	COG3830	Belongs to the UPF0237 family
G0030_00365	COG0753	catalase activity
G0030_00415	COG2175	clavaminate synthase activity
G0030_00420	COG0534	Mate efflux family protein
G0030_00425	COG0436	Aminotransferase
G0030_00430	COG2733	membrane
G0030_00445	COG2918	glutathione biosynthetic process
G0030_00450	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G0030_00460	COG3150	esterase
G0030_00500	COG0471	metal ion transport
G0030_00510	COG0675	Transposase, IS605 OrfB family
G0030_00515	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G0030_00520	COG4266	Belongs to the allantoicase family
G0030_00525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0030_00530	COG1247	-acetyltransferase
G0030_00570	COG0625	glutathione transferase activity
G0030_00575	COG3706	GGDEF domain
G0030_00580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G0030_00595	COG1393	Belongs to the ArsC family
G0030_00600	COG0708	Exodeoxyribonuclease III
G0030_00620	COG0189	ligase activity
G0030_00625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G0030_00630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0030_00640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G0030_00650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G0030_00680	COG2119	membrane
G0030_00685	COG0426	domain, Protein
G0030_00685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0030_00710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G0030_00735	COG1902	pentaerythritol trinitrate reductase activity
G0030_00740	COG1519	Transferase
G0030_00745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0030_00750	COG0668	transmembrane transport
G0030_00755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0030_00765	COG0431	NADPH-dependent FMN reductase
G0030_00780	COG2205	protein histidine kinase activity
G0030_00780	COG0784	Response regulator, receiver
G0030_00785	COG3162	membrane
G0030_00790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0030_00810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0030_00825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G0030_00830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0030_00840	COG2814	Major facilitator Superfamily
G0030_00845	COG0629	single-stranded DNA binding
G0030_00870	COG1196	nuclear chromosome segregation
G0030_00930	COG3293	Transposase
G0030_00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0030_00995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G0030_01000	COG3713	MltA-interacting MipA family protein
G0030_01005	COG2132	Multicopper oxidase
G0030_01020	COG2801	Transposase and inactivated derivatives
G0030_01025	COG3077	Addiction module antitoxin, RelB DinJ family
G0030_01035	COG2801	Transposase and inactivated derivatives
G0030_01060	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
G0030_01085	COG3158	transport of potassium into the cell
G0030_01125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G0030_01140	COG0697	spore germination
G0030_01160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G0030_01190	COG0427	acetyl-CoA hydrolase
G0030_01225	COG4221	oxidoreductase activity
G0030_01235	COG0488	(ABC) transporter
G0030_01255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0030_01265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0030_01270	COG0275	rRNA processing
G0030_01285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G0030_01290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G0030_01300	COG2226	methyltransferase
G0030_01350	COG0070	glutamate synthase
G0030_01350	COG0069	glutamate synthase activity
G0030_01350	COG0067	glutamate synthase
G0030_01355	COG0493	'glutamate synthase
G0030_01365	COG1704	LemA family
G0030_01370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G0030_01385	COG3307	-O-antigen
G0030_01395	COG3307	-O-antigen
G0030_01415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0030_01420	COG1758	RNA polymerase activity
G0030_01425	COG0194	GDP metabolic process
G0030_01435	COG2165	general secretion pathway protein
G0030_01470	COG0228	four-way junction DNA binding
G0030_01475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G0030_01485	COG0335	large ribosomal subunit rRNA binding
G0030_01510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G0030_01515	COG5380	lipid catabolic process
G0030_01520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G0030_01545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0030_01550	COG0277	FAD linked oxidase domain protein
G0030_01565	COG2814	Major facilitator Superfamily
G0030_01575	COG0628	permease
G0030_01580	COG1192	Involved in chromosome partitioning
G0030_01595	COG2226	methyltransferase
G0030_01615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G0030_01620	COG0254	rRNA binding
G0030_01625	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0030_01630	COG0534	Mate efflux family protein
G0030_01640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0030_01650	COG1960	acyl-CoA dehydrogenase activity
G0030_01665	COG0408	coproporphyrinogen oxidase activity
G0030_01670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G0030_01695	COG1127	ABC transporter
G0030_01700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G0030_01705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G0030_01710	COG2854	intermembrane phospholipid transfer
G0030_01720	COG0598	Magnesium transport protein CorA
G0030_01735	COG1040	competence protein
G0030_01740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G0030_01750	COG2937	Belongs to the GPAT DAPAT family
G0030_01755	COG1946	Acyl-CoA thioesterase
G0030_01760	COG1301	dicarboxylic acid transport
G0030_01780	COG1959	2 iron, 2 sulfur cluster binding
G0030_01790	COG0433	COG0433 Predicted ATPase
G0030_01820	COG0088	Forms part of the polypeptide exit tunnel
G0030_01850	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G0030_01885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G0030_01890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G0030_01900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G0030_01935	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G0030_01940	COG0202	RNA polymerase activity
G0030_01950	COG2072	flavoprotein involved in K transport
G0030_01955	COG1960	acyl-CoA dehydrogenase activity
G0030_01960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G0030_01985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G0030_01990	COG0697	spore germination
G0030_02000	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G0030_02005	COG0339	signal peptide processing
G0030_02015	COG0557	exoribonuclease II activity
G0030_02050	COG0179	Fumarylacetoacetate (FAA) hydrolase
G0030_02080	COG3040	lipid binding
G0030_02140	COG2813	Specifically methylates the guanine in position
G0030_02140	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0030_02145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0030_02150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G0030_02160	COG3128	pkhd-type hydroxylase
G0030_02165	COG4774	siderophore transport
G0030_02170	COG4771	TonB-dependent receptor
G0030_02180	COG0740	serine-type endopeptidase activity
G0030_02195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G0030_02195	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G0030_02205	COG0857	belongs to the CobB CobQ family
G0030_02205	COG0280	phosphate acetyltransferase
G0030_02210	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G0030_02240	COG0793	Belongs to the peptidase S41A family
G0030_02255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G0030_02270	COG0084	hydrolase, TatD family'
G0030_02275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G0030_02280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G0030_02300	COG1546	Belongs to the CinA family
G0030_02300	COG1058	Belongs to the CinA family
G0030_02320	COG2814	Major facilitator Superfamily
G0030_02325	COG0697	spore germination
G0030_02350	COG3622	Belongs to the hyi family
G0030_02360	COG1024	Enoyl-CoA hydratase
G0030_02365	COG5002	protein histidine kinase activity
G0030_02365	COG2205	protein histidine kinase activity
G0030_02365	COG0784	Response regulator, receiver
G0030_02370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0030_02385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G0030_02405	COG1862	Preprotein translocase
G0030_02420	COG1704	LemA family
G0030_02430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G0030_02450	COG5002	protein histidine kinase activity
G0030_02455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G0030_02475	COG0463	Glycosyl transferase, family 2
G0030_02515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G0030_02555	COG3223	Belongs to the PsiE family
G0030_02560	COG1960	acyl-CoA dehydrogenase activity
G0030_02565	COG1960	acyl-CoA dehydrogenase activity
G0030_02575	COG2205	protein histidine kinase activity
G0030_02580	COG0745	RESPONSE REGULATOR receiver
G0030_02590	COG2315	Protein conserved in bacteria
G0030_02595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G0030_02615	COG2096	Adenosyltransferase
G0030_02620	COG4206	TonB-dependent receptor
G0030_02665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G0030_02670	COG0285	dihydrofolate synthase activity
G0030_02685	COG0450	alkyl hydroperoxide reductase
G0030_02700	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G0030_02705	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G0030_02735	COG2199	diguanylate cyclase activity
G0030_02800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G0030_02805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G0030_02855	COG0494	nUDIX hydrolase
G0030_02865	COG1214	PFAM Peptidase M22, glycoprotease
G0030_02870	COG1968	undecaprenyl-diphosphatase activity
G0030_02890	COG4269	membrane
G0030_02905	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G0030_02915	COG2132	Multicopper oxidase
G0030_02930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G0030_02945	COG0352	thiamine-phosphate diphosphorylase activity
G0030_02945	COG0351	phosphomethylpyrimidine kinase
G0030_02945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G0030_02970	COG0251	oxidation-reduction process
G0030_02975	COG1113	amino acid transport
G0030_02980	COG1981	membrane
G0030_02995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G0030_03020	COG0456	acetyltransferase
G0030_03030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G0030_03035	COG0492	ferredoxin-NADP+ reductase activity
G0030_03040	COG1674	ftsk spoiiie
G0030_03040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G0030_03055	COG2894	cell division
G0030_03060	COG0850	regulation of cytokinetic process
G0030_03070	COG0204	Acyl-transferase
G0030_03075	COG2885	chlorophyll binding
G0030_03080	COG0210	DNA helicase
G0030_03090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0030_03105	COG0121	glutamine amidotransferase
G0030_03120	COG2914	Belongs to the UPF0125 (RnfH) family
G0030_03125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0030_03130	COG0735	belongs to the Fur family
G0030_03160	COG0420	3'-5' exonuclease activity
G0030_03180	COG2050	protein possibly involved in aromatic compounds catabolism
G0030_03185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G0030_03210	COG1649	PFAM Uncharacterised BCR, COG1649
G0030_03210	COG0726	polysaccharide deacetylase
G0030_03215	COG1215	transferase activity, transferring glycosyl groups
G0030_03230	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G0030_03260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0030_03270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G0030_03275	COG1077	Cell shape determining protein MreB Mrl
G0030_03280	COG1792	Involved in formation and maintenance of cell shape
G0030_03285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G0030_03290	COG0424	maF-like protein
G0030_03295	COG1530	ribonuclease E activity
G0030_03305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G0030_03345	COG0625	glutathione transferase activity
G0030_03365	COG1113	amino acid transport
G0030_03370	COG2828	Protein conserved in bacteria
G0030_03375	COG0142	geranyltranstransferase activity
G0030_03385	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0030_03405	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G0030_03415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G0030_03420	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0030_03425	COG0839	Belongs to the complex I subunit 6 family
G0030_03430	COG0713	ATP synthesis coupled electron transport
G0030_03435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0030_03440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G0030_03455	COG1278	Cold shock
G0030_03460	COG1278	Cold shock
G0030_03465	COG0583	DNA-binding transcription factor activity
G0030_03490	COG0668	transmembrane transport
G0030_03500	COG2081	HI0933 family
G0030_03520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G0030_03535	COG0004	ammonium transporteR
G0030_03555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0030_03555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G0030_03560	COG0489	protein tyrosine kinase activity
G0030_03575	COG2358	TRAP transporter, solute receptor (TAXI family
G0030_03610	COG0442	prolyl-tRNA aminoacylation
G0030_03645	COG0840	transmembrane signaling receptor activity
G0030_03650	COG0784	Response regulator, receiver
G0030_03650	COG2198	Histidine kinase
G0030_03650	COG0643	Histidine kinase
G0030_03665	COG5510	response to toxic substance
G0030_03675	COG2832	Protein of unknown function (DUF454)
G0030_03680	COG1376	ErfK ybiS ycfS ynhG family protein
G0030_03735	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G0030_03745	COG1289	transmembrane transporter activity
G0030_03750	COG2814	Major facilitator Superfamily
G0030_03765	COG0786	glutamate:sodium symporter activity
G0030_03770	COG1115	amino acid carrier protein
G0030_03775	COG2059	Chromate
G0030_03780	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0030_03790	COG1607	acyl-coa hydrolase
G0030_03805	COG2814	Major facilitator Superfamily
G0030_03810	COG0583	DNA-binding transcription factor activity
G0030_03830	COG0523	cobalamin synthesis protein
G0030_03835	COG4681	YaeQ
G0030_03845	COG2199	diguanylate cyclase activity
G0030_03845	COG2203	Gaf domain
G0030_03875	COG0477	Major facilitator Superfamily
G0030_03885	COG2066	Belongs to the glutaminase family
G0030_03900	COG0306	phosphate transporter
G0030_03925	COG4771	TonB-dependent receptor
G0030_03950	COG4181	ATPase activity
G0030_03955	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G0030_03965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0030_03975	COG0583	DNA-binding transcription factor activity
G0030_03985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0030_03990	COG1773	rubredoxin
G0030_03995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G0030_04025	COG3118	belongs to the thioredoxin family
G0030_04045	COG1253	flavin adenine dinucleotide binding
G0030_04065	COG3015	lipoprotein NlpE involved in copper resistance
G0030_04080	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_04100	COG0804	urea catabolic process
G0030_04120	COG0830	nickel cation binding
G0030_04135	COG0742	ribosomal rna small subunit methyltransferase
G0030_04140	COG0768	penicillin binding
G0030_04165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G0030_04170	COG2878	Part of a membrane complex involved in electron transport
G0030_04175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G0030_04185	COG3384	dioxygenase
G0030_04195	COG2234	aminopeptidase activity
G0030_04205	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G0030_04225	COG2186	Transcriptional regulator
G0030_04235	COG0277	FAD linked oxidase domain protein
G0030_04265	COG3079	Belongs to the UPF0149 family
G0030_04270	COG0006	proline dipeptidase activity
G0030_04280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0030_04285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G0030_04320	COG2816	NAD+ diphosphatase activity
G0030_04335	COG1388	LysM domain
G0030_04335	COG0741	lytic transglycosylase activity
G0030_04340	COG4166	transmembrane transport
G0030_04345	COG4174	ABC transporter (Permease)
G0030_04350	COG4239	(ABC) transporter, permease
G0030_04355	COG4172	Belongs to the ABC transporter superfamily
G0030_04385	COG0833	amino acid
G0030_04405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G0030_04410	COG0418	dihydroorotase activity
G0030_04415	COG4251	negative regulation of phosphorylation
G0030_04415	COG5001	Diguanylate cyclase
G0030_04415	COG2203	Gaf domain
G0030_04415	COG3706	GGDEF domain
G0030_04430	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0030_04430	COG1902	pentaerythritol trinitrate reductase activity
G0030_04475	COG2184	nucleotidyltransferase activity
G0030_04485	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
G0030_04520	COG3621	Patatin-like phospholipase
G0030_04565	COG2831	hemolysin activation secretion protein
G0030_04570	COG3210	domain, Protein
G0030_04580	COG0582	viral genome integration into host DNA
G0030_04615	COG2871	sodium ion transport
G0030_04645	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G0030_04665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G0030_04670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G0030_04675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G0030_04685	COG1473	amidohydrolase
G0030_04705	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G0030_04715	COG2175	clavaminate synthase activity
G0030_04735	COG0052	Belongs to the universal ribosomal protein uS2 family
G0030_04760	COG2951	lytic endotransglycosylase activity
G0030_04775	COG0842	Transport permease protein
G0030_04780	COG1131	(ABC) transporter
G0030_04835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0030_04855	COG3634	alkyl hydroperoxide reductase activity
G0030_04860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0030_04865	COG0826	peptidase U32
G0030_04875	COG0640	Transcriptional regulator
G0030_04885	COG0798	PFAM Bile acid sodium symporter
G0030_04890	COG0431	NADPH-dependent FMN reductase
G0030_04895	COG0789	Transcriptional regulator
G0030_04910	COG1720	tRNA m6t6A37 methyltransferase activity
G0030_04925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G0030_04960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G0030_04965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G0030_04970	COG3139	Protein of unknown function (DUF1315)
G0030_04980	COG1301	dicarboxylic acid transport
G0030_04985	COG1960	acyl-CoA dehydrogenase activity
G0030_04990	COG0693	protein deglycase activity
G0030_05000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G0030_05005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G0030_05030	COG1047	Peptidyl-prolyl cis-trans
G0030_05035	COG1252	NADH dehydrogenase
G0030_05040	COG1686	Belongs to the peptidase S11 family
G0030_05055	COG1187	pseudouridine synthase activity
G0030_05070	COG0739	heme binding
G0030_05080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0030_05090	COG0612	Peptidase, M16
G0030_05125	COG0352	thiamine-phosphate diphosphorylase activity
G0030_05140	COG2801	Transposase and inactivated derivatives
G0030_05170	COG0596	Alpha beta hydrolase
G0030_05175	COG1309	transcriptional regulator
G0030_05200	COG3328	transposase activity
G0030_05220	COG3328	transposase activity
G0030_05255	COG1278	Cold shock
G0030_05270	COG2070	2-Nitropropane dioxygenase
G0030_05295	COG2391	methyltransferase activity
G0030_05310	COG3634	alkyl hydroperoxide reductase activity
G0030_05340	COG1643	Atp-dependent helicase
G0030_05365	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G0030_05365	COG0517	IMP dehydrogenase activity
G0030_05370	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G0030_05380	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G0030_05385	COG1137	ATPase activity
G0030_05395	COG2274	protein secretion by the type I secretion system
G0030_05420	COG4122	O-methyltransferase activity
G0030_05430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G0030_05470	COG1454	alcohol dehydrogenase
G0030_05500	COG2011	ABC-type metal ion transport system permease component
G0030_05505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G0030_05525	COG0138	bifunctional purine biosynthesis protein purh
G0030_05530	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G0030_05570	COG2308	Evidence 4 Homologs of previously reported genes of
G0030_05580	COG1305	Transglutaminase-like
G0030_05595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G0030_05610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G0030_05615	COG0360	Binds together with S18 to 16S ribosomal RNA
G0030_05625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G0030_05630	COG1845	cytochrome c oxidase, subunit III
G0030_05635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G0030_05640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G0030_05665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G0030_05680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G0030_05690	COG3781	membrane
G0030_05710	COG1960	acyl-CoA dehydrogenase activity
G0030_05715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G0030_05725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G0030_05735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G0030_05750	COG0477	Major facilitator Superfamily
G0030_05790	COG0786	glutamate:sodium symporter activity
G0030_05820	COG0308	aminopeptidase N
G0030_05830	COG0589	response to stress
G0030_05835	COG0589	response to stress
G0030_05845	COG3135	benzoate transporter
G0030_05855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G0030_05870	COG0183	Belongs to the thiolase family
G0030_05880	COG2030	dehydratase
G0030_05885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G0030_05895	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G0030_05900	COG0824	Thioesterase
G0030_05905	COG1454	alcohol dehydrogenase
G0030_05910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G0030_05930	COG0069	glutamate synthase activity
G0030_05940	COG4585	Histidine kinase
G0030_05945	COG2850	peptidyl-arginine hydroxylation
G0030_05950	COG0424	maF-like protein
G0030_05975	COG0697	spore germination
G0030_06015	COG3698	Phosphodiester glycosidase
G0030_06035	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0030_06035	COG0506	proline dehydrogenase activity
G0030_06035	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G0030_06045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0030_06050	COG1027	Aspartate ammonia-lyase
G0030_06055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G0030_06060	COG0583	DNA-binding transcription factor activity
G0030_06065	COG1960	acyl-CoA dehydrogenase activity
G0030_06095	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0030_06095	COG1902	pentaerythritol trinitrate reductase activity
G0030_06125	COG0148	phosphopyruvate hydratase activity
G0030_06140	COG0772	Belongs to the SEDS family
G0030_06155	COG2137	regulation of response to DNA damage stimulus
G0030_06165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G0030_06170	COG1011	Hydrolase
G0030_06190	COG0268	Binds directly to 16S ribosomal RNA
G0030_06195	COG0702	epimerase
G0030_06200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G0030_06215	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G0030_06245	COG0316	Belongs to the HesB IscA family
G0030_06250	COG0822	iron-sulfur transferase activity
G0030_06280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0030_06305	COG0537	adenosine 5'-monophosphoramidase activity
G0030_06335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G0030_06355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0030_06365	COG0133	tryptophan synthase activity
G0030_06370	COG0617	tRNA 3'-terminal CCA addition
G0030_06370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0030_06370	COG0517	IMP dehydrogenase activity
G0030_06400	COG0612	Peptidase, M16
G0030_06405	COG0552	protein localization to endoplasmic reticulum
G0030_06450	COG0693	protein deglycase activity
G0030_06460	COG1283	sodium-dependent phosphate transmembrane transporter activity
G0030_06470	COG1346	cytolysis
G0030_06480	COG0583	DNA-binding transcription factor activity
G0030_06500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G0030_06505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0030_06520	COG1629	transport
G0030_06535	COG1960	acyl-CoA dehydrogenase activity
G0030_06540	COG2207	Transcriptional regulator
G0030_06545	COG2814	Major facilitator Superfamily
G0030_06555	COG1271	oxidase subunit
G0030_06560	COG1294	oxidase, subunit
G0030_06570	COG1525	nuclease
G0030_06620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0030_06625	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G0030_06640	COG1113	amino acid transport
G0030_06650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0030_06660	COG2814	Major facilitator Superfamily
G0030_06680	COG1132	(ABC) transporter
G0030_06695	COG0668	transmembrane transport
G0030_06700	COG3122	Protein conserved in bacteria
G0030_06720	COG0640	Transcriptional regulator
G0030_06725	COG2937	Belongs to the GPAT DAPAT family
G0030_06730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G0030_06735	COG1116	anion transmembrane transporter activity
G0030_06735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G0030_06745	COG2223	nitrite transmembrane transporter activity
G0030_06750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0030_06755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0030_06770	COG0243	molybdopterin cofactor binding
G0030_06780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G0030_06795	COG0521	Mo-molybdopterin cofactor biosynthetic process
G0030_06795	COG0315	cyclic pyranopterin monophosphate synthase activity
G0030_06800	COG0303	'Molybdopterin
G0030_06810	COG4149	molybdate abc transporter
G0030_06815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G0030_06820	COG0583	DNA-binding transcription factor activity
G0030_06840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0030_06845	COG0183	Belongs to the thiolase family
G0030_06850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0030_06855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0030_06860	COG3135	benzoate transporter
G0030_06865	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_06870	COG0543	2 iron, 2 sulfur cluster binding
G0030_06870	COG0633	Ferredoxin
G0030_06875	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G0030_06880	COG4638	Rieske (2fe-2S)
G0030_06890	COG4829	muconolactone delta-isomerase
G0030_06895	COG4948	Mandelate Racemase Muconate Lactonizing
G0030_06900	COG0583	DNA-binding transcription factor activity
G0030_06905	COG2814	Major facilitator Superfamily
G0030_06935	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_06945	COG2223	nitrite transmembrane transporter activity
G0030_06955	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
G0030_06960	COG2116	formate transmembrane transporter activity
G0030_06965	COG0515	serine threonine protein kinase
G0030_06970	COG0644	oxidoreductase
G0030_06970	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0030_06980	COG1960	acyl-CoA dehydrogenase activity
G0030_06985	COG1960	acyl-CoA dehydrogenase activity
G0030_06990	COG2814	Major facilitator Superfamily
G0030_06995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G0030_07000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0030_07005	COG2814	Major facilitator Superfamily
G0030_07015	COG2814	Major facilitator Superfamily
G0030_07020	COG1024	Enoyl-CoA hydratase
G0030_07025	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0030_07030	COG0183	Belongs to the thiolase family
G0030_07040	COG0235	Class ii aldolase
G0030_07045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G0030_07050	COG1024	Enoyl-CoA hydratase
G0030_07060	COG1960	acyl-CoA dehydrogenase activity
G0030_07065	COG2226	methyltransferase
G0030_07065	COG0596	Alpha beta hydrolase
G0030_07065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0030_07075	COG2814	Major facilitator Superfamily
G0030_07080	COG3293	Transposase
G0030_07085	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_07095	COG2814	Major facilitator Superfamily
G0030_07100	COG1846	Transcriptional regulator
G0030_07105	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_07110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G0030_07120	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_07150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0030_07185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G0030_07190	COG1309	transcriptional regulator
G0030_07195	COG1012	belongs to the aldehyde dehydrogenase family
G0030_07225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G0030_07245	COG2885	chlorophyll binding
G0030_07255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G0030_07260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G0030_07265	COG0730	response to heat
G0030_07340	COG2801	Transposase and inactivated derivatives
G0030_07430	COG0596	Alpha beta hydrolase
G0030_07465	COG0511	ligase activity, forming carbon-carbon bonds
G0030_07470	COG0439	Biotin carboxylase
G0030_07485	COG2814	Major facilitator Superfamily
G0030_07540	COG1058	Belongs to the CinA family
G0030_07540	COG1546	Belongs to the CinA family
G0030_07550	COG0372	Belongs to the citrate synthase family
G0030_07585	COG0542	response to heat
G0030_07590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G0030_07610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G0030_07620	COG0569	domain protein
G0030_07625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G0030_07645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G0030_07655	COG1585	Membrane protein implicated in regulation of membrane protease activity
G0030_07670	COG1294	oxidase, subunit
G0030_07675	COG4890	Cyd operon protein YbgT
G0030_07710	COG1960	acyl-CoA dehydrogenase activity
G0030_07715	COG1960	acyl-CoA dehydrogenase activity
G0030_07725	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G0030_07730	COG2207	Transcriptional regulator
G0030_07735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0030_07740	COG0730	response to heat
G0030_07745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G0030_07775	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G0030_07810	COG0575	Belongs to the CDS family
G0030_07815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G0030_07820	COG0233	cytoplasmic translational termination
G0030_07835	COG3852	Histidine kinase
G0030_07840	COG2204	response regulator
G0030_07850	COG0583	DNA-binding transcription factor activity
G0030_07880	COG1253	flavin adenine dinucleotide binding
G0030_07900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G0030_07905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G0030_07920	COG2431	L-lysine efflux transmembrane transporter activity
G0030_07925	COG0284	orotidine-5'-phosphate decarboxylase activity
G0030_07935	COG0776	regulation of translation
G0030_07965	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G0030_08000	COG0084	hydrolase, TatD family'
G0030_08020	COG1663	tetraacyldisaccharide 4'-kinase activity
G0030_08025	COG1132	(ABC) transporter
G0030_08035	COG0811	peptide transport
G0030_08040	COG1475	DNA binding
G0030_08045	COG1192	Involved in chromosome partitioning
G0030_08055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G0030_08060	COG3178	'Phosphotransferase
G0030_08070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0030_08075	COG1923	regulation of RNA biosynthetic process
G0030_08085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G0030_08090	COG0802	atpase or kinase
G0030_08115	COG2707	UPF0756 membrane protein
G0030_08125	COG0583	DNA-binding transcription factor activity
G0030_08130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0030_08160	COG0519	Catalyzes the synthesis of GMP from XMP
G0030_08160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0030_08165	COG2353	YceI-like domain
G0030_08175	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G0030_08180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G0030_08220	COG1254	Belongs to the acylphosphatase family
G0030_08225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G0030_08225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G0030_08230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G0030_08250	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_08260	COG3327	negative regulation of DNA-templated transcription, initiation
G0030_08265	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G0030_08270	COG0183	Belongs to the thiolase family
G0030_08275	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0030_08280	COG1024	Enoyl-CoA hydratase
G0030_08285	COG1024	Enoyl-CoA hydratase
G0030_08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G0030_08295	COG2151	metal-sulfur cluster biosynthetic enzyme
G0030_08300	COG3396	Phenylacetate-CoA oxygenase
G0030_08305	COG3460	Phenylacetate-CoA oxygenase
G0030_08310	COG3396	Phenylacetate-CoA oxygenase
G0030_08315	COG1012	belongs to the aldehyde dehydrogenase family
G0030_08315	COG2030	dehydratase
G0030_08320	COG2814	Major facilitator Superfamily
G0030_08325	COG0783	Belongs to the Dps family
G0030_08385	COG5002	protein histidine kinase activity
G0030_08385	COG5001	Diguanylate cyclase
G0030_08395	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
G0030_08415	COG4773	Receptor
G0030_08445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G0030_08480	COG0642	Histidine kinase
G0030_08495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G0030_08520	COG2816	NAD+ diphosphatase activity
G0030_08525	COG3046	protein related to deoxyribodipyrimidine photolyase
G0030_08560	COG0204	Acyl-transferase
G0030_08590	COG0012	GTP binding
G0030_08600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G0030_08615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G0030_08625	COG0386	Belongs to the glutathione peroxidase family
G0030_08630	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G0030_08635	COG0436	Aminotransferase
G0030_08640	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G0030_08640	COG2755	lipolytic protein G-D-S-L family
G0030_08680	COG0515	serine threonine protein kinase
G0030_08680	COG2815	serine threonine protein kinase
G0030_08710	COG1610	YqeY-like protein
G0030_08725	COG4783	chaperone-mediated protein folding
G0030_08790	COG0513	Belongs to the DEAD box helicase family
G0030_08820	COG2363	Small membrane protein
G0030_08840	COG0659	secondary active sulfate transmembrane transporter activity
G0030_08850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G0030_08870	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_08875	COG1309	transcriptional regulator
G0030_08880	COG1960	acyl-CoA dehydrogenase activity
G0030_08885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G0030_08890	COG1024	Enoyl-CoA hydratase
G0030_08895	COG4770	biotin carboxylase activity
G0030_08910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G0030_08925	COG0540	Belongs to the ATCase OTCase family
G0030_08945	COG1765	OsmC-like protein
G0030_08955	COG0667	Aldo Keto reductase
G0030_08970	COG0501	Belongs to the peptidase M48B family
G0030_08975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G0030_08990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G0030_09000	COG0527	aspartate kinase activity
G0030_09010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G0030_09020	COG1215	transferase activity, transferring glycosyl groups
G0030_09030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G0030_09035	COG2252	PERMEase
G0030_09065	COG0714	Associated with various cellular activities
G0030_09070	COG2879	small protein
G0030_09075	COG1966	Carbon starvation protein
G0030_09080	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G0030_09095	COG0488	(ABC) transporter
G0030_09105	COG1509	lysine 2,3-aminomutase activity
G0030_09140	COG1067	ATP-dependent peptidase activity
G0030_09145	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G0030_09150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G0030_09155	COG0583	DNA-binding transcription factor activity
G0030_09165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G0030_09180	COG1686	Belongs to the peptidase S11 family
G0030_09185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G0030_09190	COG2801	Transposase and inactivated derivatives
G0030_09195	COG1959	2 iron, 2 sulfur cluster binding
G0030_09205	COG2801	Transposase and inactivated derivatives
G0030_09235	COG3385	transposase activity
G0030_09240	COG0616	signal peptide processing
G0030_09245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G0030_09255	COG0573	inorganic phosphate transmembrane transporter activity
G0030_09265	COG0076	glutamate decarboxylase activity
G0030_09270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G0030_09280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G0030_09290	COG2814	Major facilitator Superfamily
G0030_09295	COG1733	regulation of RNA biosynthetic process
G0030_09300	COG0702	epimerase
G0030_09330	COG0556	nucleotide-excision repair
G0030_09350	COG0436	Aminotransferase
G0030_09370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G0030_09375	COG1381	Involved in DNA repair and RecF pathway recombination
G0030_09385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G0030_09390	COG0571	ribonuclease III activity
G0030_09400	COG0681	Belongs to the peptidase S26 family
G0030_09415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G0030_09425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G0030_09440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G0030_09450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G0030_09465	COG4208	sulfate ABC transporter
G0030_09470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G0030_09475	COG0583	DNA-binding transcription factor activity
G0030_09500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G0030_09510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G0030_09515	COG2353	YceI-like domain
G0030_09520	COG1056	cytidyltransferase-related domain
G0030_09520	COG1051	belongs to the nudix hydrolase family
G0030_09525	COG1024	Enoyl-CoA hydratase
G0030_09530	COG0778	Nitroreductase
G0030_09545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G0030_09545	COG0047	phosphoribosylformylglycinamidine synthase activity
G0030_09565	COG2255	four-way junction helicase activity
G0030_09575	COG0824	Thioesterase
G0030_09595	COG0823	Involved in the tonB-independent uptake of proteins
G0030_09615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0030_09645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G0030_09650	COG0628	permease
G0030_09655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G0030_09660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G0030_09680	COG0658	competence protein
G0030_09680	COG2333	competence protein COMEC
G0030_09685	COG1136	(ABC) transporter
G0030_09690	COG4591	ABC-type transport system involved in lipoprotein release permease component
G0030_09705	COG1671	Belongs to the UPF0178 family
G0030_09745	COG1280	lysine exporter protein (LysE YggA)
G0030_09750	COG1522	sequence-specific DNA binding
G0030_09760	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G0030_09775	COG0019	diaminopimelate decarboxylase activity
G0030_09785	COG1113	amino acid transport
G0030_09790	COG1115	amino acid carrier protein
G0030_09810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G0030_09815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G0030_09850	COG0583	DNA-binding transcription factor activity
G0030_09860	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G0030_09870	COG0174	glutamine synthetase
G0030_09875	COG0512	Glutamine amidotransferase of anthranilate synthase
G0030_09895	COG0302	gtp cyclohydrolase
G0030_09905	COG3706	GGDEF domain
G0030_09920	COG3739	integral membrane protein
G0030_09925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G0030_09935	COG1741	Belongs to the pirin family
G0030_09940	COG3842	ATPase activity
G0030_09945	COG1840	ABC-type Fe3 transport system, periplasmic component
G0030_09965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G0030_09970	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G0030_09980	COG0037	tRNA processing
G0030_09985	COG0741	lytic transglycosylase activity
G0030_09985	COG0739	heme binding
G0030_09985	COG1196	nuclear chromosome segregation
G0030_09990	COG0501	Belongs to the peptidase M48B family
G0030_10000	COG2239	Acts as a magnesium transporter
G0030_10010	COG0584	glycerophosphoryl diester phosphodiesterase
G0030_10035	COG1597	lipid kinase activity
G0030_10055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G0030_10085	COG3293	Transposase
G0030_10095	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G0030_10105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G0030_10110	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G0030_10115	COG1534	Rna-binding protein
G0030_10130	COG0505	Belongs to the CarA family
G0030_10145	COG0415	Belongs to the DNA photolyase family
G0030_10150	COG0110	maltose O-acetyltransferase activity
G0030_10155	COG0589	response to stress
G0030_10165	COG2321	neutral zinc metallopeptidase
G0030_10170	COG2354	Protein conserved in bacteria
G0030_10185	COG2268	Band 7 protein
G0030_10195	COG1215	transferase activity, transferring glycosyl groups
G0030_10200	COG1649	PFAM Uncharacterised BCR, COG1649
G0030_10200	COG0726	polysaccharide deacetylase
G0030_10210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G0030_10220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G0030_10235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G0030_10240	COG1053	succinate dehydrogenase
G0030_10245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G0030_10260	COG2072	flavoprotein involved in K transport
G0030_10265	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_10275	COG2425	protein containing a von Willebrand factor type A (vWA) domain
G0030_10280	COG0714	Associated with various cellular activities
G0030_10290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G0030_10290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0030_10320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0030_10330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G0030_10345	COG0564	pseudouridine synthase activity
G0030_10355	COG0358	DNA primase activity
G0030_10370	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G0030_10400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G0030_10440	COG0586	Pfam SNARE associated Golgi protein
G0030_10465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G0030_10475	COG0321	lipoyl(octanoyl) transferase activity
G0030_10490	COG0531	amino acid
G0030_10495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G0030_10500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G0030_10500	COG1648	precorrin-2 dehydrogenase activity
G0030_10505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G0030_10515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G0030_10540	COG0671	phosphoesterase, PA-phosphatase related
G0030_10545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0030_10555	COG1538	Outer membrane efflux protein
G0030_10565	COG0393	Putative heavy-metal-binding
G0030_10570	COG0393	Putative heavy-metal-binding
G0030_10585	COG0525	valine-tRNA ligase activity
G0030_10615	COG2323	membrane
G0030_10625	COG0765	amino acid transport
G0030_10630	COG0765	amino acid transport
G0030_10635	COG1126	abc transporter atp-binding protein
G0030_10640	COG3338	carbonate dehydratase activity
G0030_10655	COG1752	Esterase of the alpha-beta hydrolase superfamily
G0030_10670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G0030_10675	COG2205	protein histidine kinase activity
G0030_10680	COG0745	RESPONSE REGULATOR receiver
G0030_10695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G0030_10715	COG1652	LysM domain
G0030_10725	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_10740	COG1399	metal-binding, possibly nucleic acid-binding protein
G0030_10745	COG3101	peptidyl-lysine hydroxylation
G0030_10750	COG0009	L-threonylcarbamoyladenylate synthase
G0030_10760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G0030_10765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G0030_10780	COG4106	trans-aconitate 2-methyltransferase activity
G0030_10795	COG0596	Alpha beta hydrolase
G0030_10795	COG2226	methyltransferase
G0030_10795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G0030_10800	COG2193	ferroxidase activity
G0030_10805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G0030_10810	COG3115	cell septum assembly
G0030_10815	COG1196	nuclear chromosome segregation
G0030_10825	COG0730	response to heat
G0030_10845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G0030_10860	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_10865	COG2801	Transposase and inactivated derivatives
G0030_10880	COG0628	permease
G0030_10890	COG2824	Alkylphosphonate utilization operon protein PhnA
G0030_10895	COG3189	MarR family transcriptional regulator
G0030_10910	COG0564	pseudouridine synthase activity
G0030_10915	COG0346	lactoylglutathione lyase activity
G0030_10945	COG0354	folic acid binding
G0030_10975	COG0363	glucosamine-6-phosphate deaminase activity
G0030_10985	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G0030_10990	COG1877	trehalose-phosphatase activity
G0030_11000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G0030_11005	COG1970	mechanosensitive ion channel activity
G0030_11010	COG1217	gtp-binding protein TYPA
G0030_11015	COG2233	PERMEase
G0030_11025	COG0833	amino acid
G0030_11045	COG0183	Belongs to the thiolase family
G0030_11060	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G0030_11065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G0030_11070	COG2207	Transcriptional regulator
G0030_11075	COG0183	Belongs to the thiolase family
G0030_11080	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0030_11080	COG1024	Enoyl-CoA hydratase
G0030_11100	COG1272	protein, Hemolysin III
G0030_11105	COG0477	Major facilitator Superfamily
G0030_11115	COG1408	metallophosphoesterase
G0030_11120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G0030_11130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G0030_11160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G0030_11165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G0030_11170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G0030_11180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G0030_11185	COG0625	glutathione transferase activity
G0030_11190	COG2969	positive regulation of protein catabolic process
G0030_11240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G0030_11285	COG0037	tRNA processing
G0030_11295	COG0248	Ppx GppA phosphatase
G0030_11320	COG0072	phenylalanine-tRNA ligase activity
G0030_11355	COG1238	metal cluster binding
G0030_11360	COG0625	glutathione transferase activity
G0030_11375	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_11380	COG3028	Belongs to the UPF0307 family
G0030_11390	COG1660	Displays ATPase and GTPase activities
G0030_11405	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G0030_11410	COG0617	tRNA 3'-terminal CCA addition
G0030_11415	COG1555	photosystem II stabilization
G0030_11420	COG3956	TIGRFAM MazG family protein
G0030_11435	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G0030_11445	COG0124	histidyl-tRNA synthetase
G0030_11475	COG2975	iron-sulfur cluster assembly
G0030_11515	COG0440	acetolactate synthase activity
G0030_11520	COG0028	Belongs to the TPP enzyme family
G0030_11545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0030_11550	COG0577	efflux transmembrane transporter activity
G0030_11550	COG1136	(ABC) transporter
G0030_11600	COG2826	transposase and inactivated derivatives, IS30 family
G0030_11685	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G0030_11690	COG1162	GTPase activity
G0030_11700	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G0030_11710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G0030_11720	COG3781	membrane
G0030_11725	COG0613	PHP domain protein
G0030_11735	COG2350	Protein conserved in bacteria
G0030_11755	COG1666	GTP binding
G0030_11765	COG1607	acyl-coa hydrolase
G0030_11830	COG1183	phosphatidylcholine synthase activity
G0030_11835	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G0030_11865	COG3385	transposase activity
G0030_11880	COG0741	lytic transglycosylase activity
G0030_11880	COG1196	nuclear chromosome segregation
G0030_11880	COG0739	heme binding
G0030_11890	COG1702	phosphate starvation-inducible protein PhoH
G0030_11940	COG1295	ribonuclease BN
G0030_11970	COG0788	formyltetrahydrofolate deformylase activity
G0030_11995	COG4651	solute:proton antiporter activity
G0030_11995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G0030_12010	COG0724	RNA recognition motif
G0030_12015	COG0210	DNA helicase
G0030_12025	COG1929	Belongs to the glycerate kinase type-1 family
G0030_12055	COG2900	Belongs to the SlyX family
G0030_12060	COG0488	(ABC) transporter
G0030_12065	COG1560	Kdo2-lipid A biosynthetic process
G0030_12120	COG0473	3-isopropylmalate dehydrogenase activity
G0030_12135	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G0030_12150	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G0030_12165	COG0494	nUDIX hydrolase
G0030_12185	COG1960	acyl-CoA dehydrogenase activity
G0030_12195	COG0753	catalase activity
G0030_12210	COG0446	pyridine nucleotide-disulphide oxidoreductase
G0030_12215	COG3384	dioxygenase
G0030_12220	COG1028	Short-chain dehydrogenase reductase Sdr
G0030_12235	COG4638	Rieske (2fe-2S)
G0030_12240	COG0583	DNA-binding transcription factor activity
G0030_12265	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G0030_12270	COG3971	2-oxopent-4-enoate hydratase activity
G0030_12275	COG0546	phosphoglycolate phosphatase activity
G0030_12285	COG1530	ribonuclease E activity
G0030_12290	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_12315	COG1983	PspC domain protein
G0030_12320	COG0517	IMP dehydrogenase activity
G0030_12320	COG0617	tRNA 3'-terminal CCA addition
G0030_12320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G0030_12330	COG0751	glycine-tRNA ligase activity
G0030_12360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G0030_12375	COG2226	methyltransferase
G0030_12385	COG0493	'glutamate synthase
G0030_12385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G0030_12395	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G0030_12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G0030_12420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G0030_12430	COG0644	oxidoreductase
G0030_12430	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G0030_12525	COG0425	Belongs to the sulfur carrier protein TusA family
G0030_12530	COG4535	Mg2 and Co2 transporter CorC
G0030_12535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G0030_12555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G0030_12565	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G0030_12575	COG0789	Transcriptional regulator
G0030_12580	COG2841	Protein conserved in bacteria
G0030_12595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G0030_12600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0030_12605	COG1074	ATP-dependent DNA helicase activity
G0030_12610	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G0030_12640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G0030_12650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G0030_12665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G0030_12665	COG2111	Na H antiporter
G0030_12670	COG1006	Multisubunit Na H antiporter MnhC subunit
G0030_12675	COG0651	ATP synthesis coupled electron transport
G0030_12680	COG1863	multisubunit Na H antiporter MnhE subunit
G0030_12685	COG2212	antiporter activity
G0030_12690	COG1320	monovalent cation:proton antiporter activity
G0030_12695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G0030_12705	COG0195	Participates in both transcription termination and antitermination
G0030_12710	COG0779	Required for maturation of 30S ribosomal subunits
G0030_12760	COG0237	dephospho-CoA kinase activity
G0030_12770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G0030_12775	COG3123	guanosine phosphorylase activity
G0030_12780	COG0497	DNA recombination
G0030_12790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G0030_12805	COG1132	(ABC) transporter
G0030_12810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G0030_12845	COG1250	3-hydroxyacyl-CoA dehydrogenase
G0030_12845	COG1024	Enoyl-CoA hydratase
G0030_12855	COG2233	PERMEase
G0030_12865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G0030_12895	COG0326	Molecular chaperone. Has ATPase activity
G0030_12910	COG2056	Na+-H+ antiporter family
G0030_12930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G0030_12935	COG0085	RNA polymerase activity
G0030_12950	COG0081	regulation of translation
G0030_13035	COG0824	Thioesterase
G0030_13055	COG0181	hydroxymethylbilane synthase activity
G0030_13065	COG3275	phosphorelay sensor kinase activity
G0030_13100	COG0494	nUDIX hydrolase
G0030_13105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G0030_13110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G0030_13115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G0030_13125	COG0772	Belongs to the SEDS family
G0030_13150	COG4974	Belongs to the 'phage' integrase family
G0030_13165	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G0030_13175	COG2197	response regulator
G0030_13190	COG0793	Belongs to the peptidase S41A family
G0030_13195	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G0030_13200	COG0795	lipopolysaccharide-transporting ATPase activity
G0030_13205	COG0795	lipopolysaccharide-transporting ATPase activity
G0030_13230	COG0586	Pfam SNARE associated Golgi protein
G0030_13245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0030_13245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G0030_13255	COG0004	ammonium transporteR
G0030_13260	COG0347	Belongs to the P(II) protein family
G0030_13285	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G0030_13300	COG0318	PFAM AMP-dependent synthetase and ligase
G0030_13310	COG0477	Major facilitator Superfamily
G0030_13315	COG2860	membrane
G0030_13325	COG1253	flavin adenine dinucleotide binding
G0030_13345	COG2814	Major facilitator Superfamily
G0030_13360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0030_13380	COG2814	Major facilitator Superfamily
G0030_13430	COG0758	DNA mediated transformation
G0030_13440	COG0697	spore germination
G0030_13445	COG0386	Belongs to the glutathione peroxidase family
G0030_13470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G0030_13520	COG1121	(ABC) transporter
G0030_13525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G0030_13535	COG2837	iron assimilation
G0030_13540	COG3328	transposase activity
G0030_13565	COG0281	malic enzyme
G0030_13605	COG1715	Restriction endonuclease
G0030_13610	COG0519	Catalyzes the synthesis of GMP from XMP
G0030_13610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G0030_13615	COG2259	Doxx family
G0030_13620	COG0586	Pfam SNARE associated Golgi protein
G0030_13635	COG1192	Involved in chromosome partitioning
G0030_13645	COG0271	Belongs to the BolA IbaG family
G0030_13680	COG3756	Protein conserved in bacteria
G0030_13700	COG3586	endonuclease activity
G0030_13770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G0030_13775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G0030_13790	COG1570	exodeoxyribonuclease VII activity
G0030_13835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G0030_13845	COG3173	Aminoglycoside phosphotransferase
G0030_13895	COG2801	Transposase and inactivated derivatives
G0030_13900	COG0659	secondary active sulfate transmembrane transporter activity
G0030_13945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G0030_13960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G0030_13970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G0030_13980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G0030_13995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G0030_14010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G0030_14035	COG1086	Polysaccharide biosynthesis protein
G0030_14045	COG0110	maltose O-acetyltransferase activity
G0030_14060	COG0438	transferase activity, transferring glycosyl groups
G0030_14080	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G0030_14135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G0030_14140	COG1309	transcriptional regulator
G0030_14150	COG2233	PERMEase
G0030_14165	COG0129	dihydroxy-acid dehydratase activity
G0030_14180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G0030_14190	COG0733	neurotransmitter:sodium symporter activity
G0030_14195	COG1012	belongs to the aldehyde dehydrogenase family
G0030_14205	COG2814	Major facilitator Superfamily
G0030_14235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G0030_14245	COG0657	acetylesterase activity
G0030_14280	COG2951	lytic endotransglycosylase activity
G0030_14285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G0030_14305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G0030_14315	COG2388	GCN5-related N-acetyl-transferase
G0030_14325	COG0861	Integral membrane protein TerC family
G0030_14330	COG0402	S-adenosylhomocysteine deaminase activity
G0030_14345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G0030_14350	COG1230	cation diffusion facilitator family transporter
G0030_14375	COG0706	membrane insertase activity
G0030_14380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G0030_14385	COG0594	ribonuclease P activity
G0030_14400	COG3173	Aminoglycoside phosphotransferase
G0030_14405	COG0488	(ABC) transporter
G0030_14410	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G0030_14415	COG3657	addiction module killer protein
G0030_14505	COG0488	(ABC) transporter
G0030_14520	COG0488	(ABC) transporter