locus-tag	class	description
CTZ23_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CTZ23_00010	COG0592	DNA-directed DNA polymerase activity
CTZ23_00020	COG0187	DNA topoisomerase II activity
CTZ23_00025	COG1063	alcohol dehydrogenase
CTZ23_00030	COG3328	transposase activity
CTZ23_00035	COG0488	(ABC) transporter
CTZ23_00060	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ23_00065	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ23_00080	COG0737	Belongs to the 5'-nucleotidase family
CTZ23_00110	COG2814	Major facilitator Superfamily
CTZ23_00115	COG2133	pyrroloquinoline quinone binding
CTZ23_00125	COG1047	Peptidyl-prolyl cis-trans
CTZ23_00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CTZ23_00135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ23_00140	COG0196	riboflavin kinase activity
CTZ23_00150	COG1309	transcriptional regulator
CTZ23_00155	COG1116	anion transmembrane transporter activity
CTZ23_00160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ23_00165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_00170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_00175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_00180	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CTZ23_00180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CTZ23_00200	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_00205	COG0546	phosphoglycolate phosphatase activity
CTZ23_00210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ23_00220	COG1309	transcriptional regulator
CTZ23_00225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CTZ23_00235	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ23_00255	COG1064	alcohol dehydrogenase
CTZ23_00260	COG2818	Glycosylase
CTZ23_00270	COG0739	heme binding
CTZ23_00275	COG1194	a g-specific adenine glycosylase
CTZ23_00290	COG5487	UPF0391 membrane protein
CTZ23_00295	COG2983	Belongs to the UPF0260 family
CTZ23_00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ23_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CTZ23_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ23_00325	COG1335	isochorismatase
CTZ23_00330	COG0385	Bile acid
CTZ23_00345	COG3830	Belongs to the UPF0237 family
CTZ23_00345	COG0560	Phosphoserine phosphatase
CTZ23_00365	COG0753	catalase activity
CTZ23_00410	COG0534	Mate efflux family protein
CTZ23_00415	COG0436	Aminotransferase
CTZ23_00420	COG2733	membrane
CTZ23_00435	COG2918	glutathione biosynthetic process
CTZ23_00440	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CTZ23_00450	COG3150	esterase
CTZ23_00465	COG0559	Belongs to the binding-protein-dependent transport system permease family
CTZ23_00480	COG0410	ABC transporter
CTZ23_00485	COG0471	metal ion transport
CTZ23_00495	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ23_00500	COG4266	Belongs to the allantoicase family
CTZ23_00505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_00510	COG1247	-acetyltransferase
CTZ23_00550	COG0625	glutathione transferase activity
CTZ23_00555	COG3706	GGDEF domain
CTZ23_00560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ23_00575	COG1393	Belongs to the ArsC family
CTZ23_00580	COG0708	Exodeoxyribonuclease III
CTZ23_00605	COG0189	ligase activity
CTZ23_00610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CTZ23_00615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_00625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ23_00635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ23_00665	COG2119	membrane
CTZ23_00670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_00670	COG0426	domain, Protein
CTZ23_00695	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ23_00720	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_00725	COG1519	Transferase
CTZ23_00730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_00735	COG0668	transmembrane transport
CTZ23_00740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_00755	COG0431	NADPH-dependent FMN reductase
CTZ23_00770	COG2205	protein histidine kinase activity
CTZ23_00770	COG0784	Response regulator, receiver
CTZ23_00775	COG3162	membrane
CTZ23_00780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_00800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_00825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ23_00830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_00850	COG2814	Major facilitator Superfamily
CTZ23_00855	COG0629	single-stranded DNA binding
CTZ23_00895	COG2801	Transposase and inactivated derivatives
CTZ23_00915	COG2801	Transposase and inactivated derivatives
CTZ23_00955	COG2205	protein histidine kinase activity
CTZ23_00960	COG3174	membrane
CTZ23_00965	COG2217	Heavy metal translocating P-type atpase
CTZ23_01005	COG3316	Transposase and inactivated derivatives
CTZ23_01075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ23_01100	COG3316	Transposase and inactivated derivatives
CTZ23_01110	COG3316	Transposase and inactivated derivatives
CTZ23_01135	COG2132	Multicopper oxidase
CTZ23_01150	COG3077	Addiction module antitoxin, RelB DinJ family
CTZ23_01180	COG0450	alkyl hydroperoxide reductase
CTZ23_01190	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CTZ23_01215	COG3158	transport of potassium into the cell
CTZ23_01255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ23_01270	COG0697	spore germination
CTZ23_01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ23_01320	COG0427	acetyl-CoA hydrolase
CTZ23_01325	COG2205	protein histidine kinase activity
CTZ23_01330	COG0745	RESPONSE REGULATOR receiver
CTZ23_01350	COG4221	oxidoreductase activity
CTZ23_01370	COG0488	(ABC) transporter
CTZ23_01390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_01400	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_01405	COG0275	rRNA processing
CTZ23_01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ23_01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ23_01435	COG2226	methyltransferase
CTZ23_01440	COG3385	transposase activity
CTZ23_01490	COG0070	glutamate synthase
CTZ23_01490	COG0069	glutamate synthase activity
CTZ23_01490	COG0067	glutamate synthase
CTZ23_01495	COG0493	'glutamate synthase
CTZ23_01505	COG1704	LemA family
CTZ23_01510	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ23_01520	COG4969	Belongs to the N-Me-Phe pilin family
CTZ23_01525	COG3307	-O-antigen
CTZ23_01535	COG3307	-O-antigen
CTZ23_01545	COG2906	2 iron, 2 sulfur cluster binding
CTZ23_01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_01560	COG1758	RNA polymerase activity
CTZ23_01565	COG0194	GDP metabolic process
CTZ23_01610	COG0228	four-way junction DNA binding
CTZ23_01615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ23_01625	COG0335	large ribosomal subunit rRNA binding
CTZ23_01630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_01635	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CTZ23_01640	COG5380	lipid catabolic process
CTZ23_01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ23_01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_01680	COG0277	FAD linked oxidase domain protein
CTZ23_01695	COG2814	Major facilitator Superfamily
CTZ23_01705	COG0628	permease
CTZ23_01710	COG1192	Involved in chromosome partitioning
CTZ23_01725	COG2226	methyltransferase
CTZ23_01745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CTZ23_01750	COG0254	rRNA binding
CTZ23_01755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_01760	COG0534	Mate efflux family protein
CTZ23_01770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_01775	COG1960	acyl-CoA dehydrogenase activity
CTZ23_01795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ23_01820	COG1127	ABC transporter
CTZ23_01825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ23_01830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTZ23_01835	COG2854	intermembrane phospholipid transfer
CTZ23_01845	COG0598	Magnesium transport protein CorA
CTZ23_01860	COG1040	competence protein
CTZ23_01865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ23_01880	COG2937	Belongs to the GPAT DAPAT family
CTZ23_01885	COG1946	Acyl-CoA thioesterase
CTZ23_01890	COG1301	dicarboxylic acid transport
CTZ23_01910	COG1959	2 iron, 2 sulfur cluster binding
CTZ23_01915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_01915	COG1017	nitric oxide dioxygenase activity
CTZ23_01920	COG0433	COG0433 Predicted ATPase
CTZ23_01945	COG0088	Forms part of the polypeptide exit tunnel
CTZ23_01975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CTZ23_02000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CTZ23_02010	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CTZ23_02015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CTZ23_02025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CTZ23_02045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CTZ23_02055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CTZ23_02060	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CTZ23_02065	COG0202	RNA polymerase activity
CTZ23_02075	COG2072	flavoprotein involved in K transport
CTZ23_02080	COG1960	acyl-CoA dehydrogenase activity
CTZ23_02085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ23_02125	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ23_02130	COG0339	signal peptide processing
CTZ23_02140	COG0557	exoribonuclease II activity
CTZ23_02175	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ23_02225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CTZ23_02235	COG3040	lipid binding
CTZ23_02295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_02295	COG2813	Specifically methylates the guanine in position
CTZ23_02300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_02305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ23_02315	COG3128	pkhd-type hydroxylase
CTZ23_02320	COG4774	siderophore transport
CTZ23_02325	COG4771	TonB-dependent receptor
CTZ23_02335	COG0740	serine-type endopeptidase activity
CTZ23_02350	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_02350	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ23_02360	COG0857	belongs to the CobB CobQ family
CTZ23_02360	COG0280	phosphate acetyltransferase
CTZ23_02365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ23_02395	COG0793	Belongs to the peptidase S41A family
CTZ23_02425	COG3046	protein related to deoxyribodipyrimidine photolyase
CTZ23_02455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTZ23_02470	COG0642	Histidine kinase
CTZ23_02475	COG0745	RESPONSE REGULATOR receiver
CTZ23_02505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ23_02530	COG4221	oxidoreductase activity
CTZ23_02535	COG0583	DNA-binding transcription factor activity
CTZ23_02540	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_02545	COG0604	alcohol dehydrogenase
CTZ23_02545	COG3321	synthase
CTZ23_02560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTZ23_02570	COG1979	alcohol dehydrogenase
CTZ23_02580	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_02590	COG1309	transcriptional regulator
CTZ23_02595	COG2130	NADP-dependent
CTZ23_02665	COG2801	Transposase and inactivated derivatives
CTZ23_02670	COG2862	Uncharacterized protein family, UPF0114
CTZ23_02695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ23_02710	COG0084	hydrolase, TatD family'
CTZ23_02715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ23_02720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ23_02785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_02855	COG2814	Major facilitator Superfamily
CTZ23_02860	COG0697	spore germination
CTZ23_02865	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ23_02870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CTZ23_02875	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CTZ23_02885	COG3622	Belongs to the hyi family
CTZ23_02895	COG1024	Enoyl-CoA hydratase
CTZ23_02900	COG5002	protein histidine kinase activity
CTZ23_02900	COG2205	protein histidine kinase activity
CTZ23_02900	COG0784	Response regulator, receiver
CTZ23_02910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_02925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_02945	COG1862	Preprotein translocase
CTZ23_02960	COG5001	Diguanylate cyclase
CTZ23_02960	COG2203	Gaf domain
CTZ23_02960	COG3706	GGDEF domain
CTZ23_02960	COG4251	negative regulation of phosphorylation
CTZ23_02965	COG1704	LemA family
CTZ23_02975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CTZ23_02995	COG5002	protein histidine kinase activity
CTZ23_03000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ23_03020	COG0463	Glycosyl transferase, family 2
CTZ23_03055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CTZ23_03095	COG1960	acyl-CoA dehydrogenase activity
CTZ23_03100	COG1960	acyl-CoA dehydrogenase activity
CTZ23_03115	COG2205	protein histidine kinase activity
CTZ23_03120	COG0745	RESPONSE REGULATOR receiver
CTZ23_03130	COG2315	Protein conserved in bacteria
CTZ23_03135	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ23_03155	COG2096	Adenosyltransferase
CTZ23_03160	COG4206	TonB-dependent receptor
CTZ23_03170	COG0133	tryptophan synthase activity
CTZ23_03205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CTZ23_03210	COG0285	dihydrofolate synthase activity
CTZ23_03225	COG0450	alkyl hydroperoxide reductase
CTZ23_03240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ23_03245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ23_03270	COG2885	chlorophyll binding
CTZ23_03330	COG2969	positive regulation of protein catabolic process
CTZ23_03335	COG0625	glutathione transferase activity
CTZ23_03340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ23_03350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CTZ23_03355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ23_03360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ23_03390	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ23_03400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_03410	COG1408	metallophosphoesterase
CTZ23_03420	COG0477	Major facilitator Superfamily
CTZ23_03425	COG1272	protein, Hemolysin III
CTZ23_03435	COG2153	protein acetylation
CTZ23_03450	COG1024	Enoyl-CoA hydratase
CTZ23_03450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_03455	COG0183	Belongs to the thiolase family
CTZ23_03460	COG2207	Transcriptional regulator
CTZ23_03470	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_03485	COG0183	Belongs to the thiolase family
CTZ23_03495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTZ23_03495	COG2885	chlorophyll binding
CTZ23_03505	COG0833	amino acid
CTZ23_03515	COG2233	PERMEase
CTZ23_03525	COG1970	mechanosensitive ion channel activity
CTZ23_03530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_03540	COG1877	trehalose-phosphatase activity
CTZ23_03545	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ23_03555	COG0363	glucosamine-6-phosphate deaminase activity
CTZ23_03585	COG0354	folic acid binding
CTZ23_03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_03610	COG0154	amidase activity
CTZ23_03615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ23_03620	COG1077	Cell shape determining protein MreB Mrl
CTZ23_03625	COG1792	Involved in formation and maintenance of cell shape
CTZ23_03630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ23_03635	COG0424	maF-like protein
CTZ23_03640	COG1530	ribonuclease E activity
CTZ23_03650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ23_03690	COG0625	glutathione transferase activity
CTZ23_03710	COG1113	amino acid transport
CTZ23_03715	COG2828	Protein conserved in bacteria
CTZ23_03720	COG0142	geranyltranstransferase activity
CTZ23_03730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_03750	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ23_03760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CTZ23_03765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_03770	COG0839	Belongs to the complex I subunit 6 family
CTZ23_03775	COG0713	ATP synthesis coupled electron transport
CTZ23_03780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_03785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ23_03800	COG1278	Cold shock
CTZ23_03805	COG0583	DNA-binding transcription factor activity
CTZ23_03810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_03830	COG0668	transmembrane transport
CTZ23_03840	COG2081	HI0933 family
CTZ23_03860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ23_03875	COG0004	ammonium transporteR
CTZ23_03900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_03900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ23_03905	COG0489	protein tyrosine kinase activity
CTZ23_03955	COG0442	prolyl-tRNA aminoacylation
CTZ23_03990	COG0840	transmembrane signaling receptor activity
CTZ23_03995	COG0643	Histidine kinase
CTZ23_03995	COG2198	Histidine kinase
CTZ23_03995	COG0643	Histidine kinase
CTZ23_03995	COG2198	Histidine kinase
CTZ23_04010	COG5510	response to toxic substance
CTZ23_04020	COG2832	Protein of unknown function (DUF454)
CTZ23_04025	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ23_04080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ23_04090	COG1289	transmembrane transporter activity
CTZ23_04095	COG2814	Major facilitator Superfamily
CTZ23_04110	COG0786	glutamate:sodium symporter activity
CTZ23_04115	COG1115	amino acid carrier protein
CTZ23_04120	COG2059	Chromate
CTZ23_04125	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_04135	COG1607	acyl-coa hydrolase
CTZ23_04170	COG0523	cobalamin synthesis protein
CTZ23_04175	COG4681	YaeQ
CTZ23_04185	COG2203	Gaf domain
CTZ23_04185	COG2199	diguanylate cyclase activity
CTZ23_04215	COG0477	Major facilitator Superfamily
CTZ23_04220	COG3706	GGDEF domain
CTZ23_04225	COG2066	Belongs to the glutaminase family
CTZ23_04230	COG2376	Dihydroxyacetone kinase
CTZ23_04250	COG0306	phosphate transporter
CTZ23_04280	COG4771	TonB-dependent receptor
CTZ23_04305	COG4181	ATPase activity
CTZ23_04310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ23_04320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_04330	COG0583	DNA-binding transcription factor activity
CTZ23_04340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_04345	COG1773	rubredoxin
CTZ23_04350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CTZ23_04370	COG0175	sulfate reduction
CTZ23_04380	COG3118	belongs to the thioredoxin family
CTZ23_04400	COG1253	flavin adenine dinucleotide binding
CTZ23_04420	COG3015	lipoprotein NlpE involved in copper resistance
CTZ23_04425	COG0204	Acyl-transferase
CTZ23_04435	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_04440	COG0829	nickel cation binding
CTZ23_04460	COG0804	urea catabolic process
CTZ23_04475	COG0830	nickel cation binding
CTZ23_04495	COG0742	ribosomal rna small subunit methyltransferase
CTZ23_04500	COG0768	penicillin binding
CTZ23_04525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ23_04530	COG2878	Part of a membrane complex involved in electron transport
CTZ23_04535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ23_04545	COG3384	dioxygenase
CTZ23_04555	COG2234	aminopeptidase activity
CTZ23_04565	COG0675	Transposase, IS605 OrfB family
CTZ23_04570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ23_04590	COG2186	Transcriptional regulator
CTZ23_04600	COG0277	FAD linked oxidase domain protein
CTZ23_04615	COG3706	GGDEF domain
CTZ23_04615	COG0745	RESPONSE REGULATOR receiver
CTZ23_04635	COG3079	Belongs to the UPF0149 family
CTZ23_04640	COG0006	proline dipeptidase activity
CTZ23_04650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_04655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ23_04690	COG2816	NAD+ diphosphatase activity
CTZ23_04705	COG1388	LysM domain
CTZ23_04705	COG0741	lytic transglycosylase activity
CTZ23_04710	COG4166	transmembrane transport
CTZ23_04715	COG4174	ABC transporter (Permease)
CTZ23_04720	COG4239	(ABC) transporter, permease
CTZ23_04725	COG4172	Belongs to the ABC transporter superfamily
CTZ23_04750	COG0833	amino acid
CTZ23_04770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ23_04775	COG0418	dihydroorotase activity
CTZ23_04780	COG4251	negative regulation of phosphorylation
CTZ23_04780	COG5001	Diguanylate cyclase
CTZ23_04780	COG3706	GGDEF domain
CTZ23_04780	COG2203	Gaf domain
CTZ23_04795	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_04795	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_04815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ23_04860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ23_04865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ23_04885	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ23_04890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ23_04895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ23_04935	COG1960	acyl-CoA dehydrogenase activity
CTZ23_04945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ23_04955	COG2175	clavaminate synthase activity
CTZ23_04970	COG0024	Methionine aminopeptidase
CTZ23_04975	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ23_05005	COG2951	lytic endotransglycosylase activity
CTZ23_05020	COG0842	Transport permease protein
CTZ23_05025	COG1131	(ABC) transporter
CTZ23_05080	COG3385	transposase activity
CTZ23_05085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_05105	COG3634	alkyl hydroperoxide reductase activity
CTZ23_05110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_05125	COG0640	Transcriptional regulator
CTZ23_05135	COG0798	PFAM Bile acid sodium symporter
CTZ23_05140	COG0431	NADPH-dependent FMN reductase
CTZ23_05145	COG0789	Transcriptional regulator
CTZ23_05160	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ23_05170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTZ23_05180	COG0745	RESPONSE REGULATOR receiver
CTZ23_05185	COG0642	Histidine kinase
CTZ23_05205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ23_05210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ23_05215	COG3139	Protein of unknown function (DUF1315)
CTZ23_05225	COG1301	dicarboxylic acid transport
CTZ23_05230	COG1960	acyl-CoA dehydrogenase activity
CTZ23_05235	COG0693	protein deglycase activity
CTZ23_05245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CTZ23_05250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ23_05270	COG0415	Belongs to the DNA photolyase family
CTZ23_05275	COG1047	Peptidyl-prolyl cis-trans
CTZ23_05280	COG1252	NADH dehydrogenase
CTZ23_05285	COG1686	Belongs to the peptidase S11 family
CTZ23_05300	COG1187	pseudouridine synthase activity
CTZ23_05310	COG0739	heme binding
CTZ23_05325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_05335	COG0612	Peptidase, M16
CTZ23_05345	COG3385	transposase activity
CTZ23_05375	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_05390	COG3328	transposase activity
CTZ23_05460	COG0596	Alpha beta hydrolase
CTZ23_05465	COG1309	transcriptional regulator
CTZ23_05535	COG1278	Cold shock
CTZ23_05550	COG2070	2-Nitropropane dioxygenase
CTZ23_05575	COG2391	methyltransferase activity
CTZ23_05585	COG3634	alkyl hydroperoxide reductase activity
CTZ23_05610	COG0450	alkyl hydroperoxide reductase
CTZ23_05615	COG1643	Atp-dependent helicase
CTZ23_05640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ23_05640	COG0517	IMP dehydrogenase activity
CTZ23_05645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ23_05655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ23_05660	COG1137	ATPase activity
CTZ23_05695	COG4122	O-methyltransferase activity
CTZ23_05705	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ23_05745	COG2011	ABC-type metal ion transport system permease component
CTZ23_05750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ23_05780	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ23_05820	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ23_05830	COG1305	Transglutaminase-like
CTZ23_05845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ23_05850	COG0305	Participates in initiation and elongation during chromosome replication
CTZ23_05860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CTZ23_05865	COG0360	Binds together with S18 to 16S ribosomal RNA
CTZ23_05875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ23_05880	COG1845	cytochrome c oxidase, subunit III
CTZ23_05885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ23_05890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ23_05915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ23_05935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CTZ23_05945	COG3781	membrane
CTZ23_05965	COG1960	acyl-CoA dehydrogenase activity
CTZ23_05970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ23_05980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CTZ23_05990	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CTZ23_06005	COG0477	Major facilitator Superfamily
CTZ23_06075	COG0308	aminopeptidase N
CTZ23_06085	COG0589	response to stress
CTZ23_06090	COG0589	response to stress
CTZ23_06100	COG3135	benzoate transporter
CTZ23_06110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ23_06125	COG0183	Belongs to the thiolase family
CTZ23_06155	COG0824	Thioesterase
CTZ23_06160	COG1454	alcohol dehydrogenase
CTZ23_06165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ23_06185	COG0069	glutamate synthase activity
CTZ23_06195	COG4585	Histidine kinase
CTZ23_06200	COG2850	peptidyl-arginine hydroxylation
CTZ23_06205	COG0424	maF-like protein
CTZ23_06230	COG0697	spore germination
CTZ23_06270	COG3698	Phosphodiester glycosidase
CTZ23_06290	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_06290	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ23_06290	COG0506	proline dehydrogenase activity
CTZ23_06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_06305	COG1027	Aspartate ammonia-lyase
CTZ23_06310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ23_06315	COG0583	DNA-binding transcription factor activity
CTZ23_06320	COG1960	acyl-CoA dehydrogenase activity
CTZ23_06325	COG2814	Major facilitator Superfamily
CTZ23_06330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ23_06345	COG1902	pentaerythritol trinitrate reductase activity
CTZ23_06345	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ23_06380	COG0148	phosphopyruvate hydratase activity
CTZ23_06395	COG0772	Belongs to the SEDS family
CTZ23_06410	COG2137	regulation of response to DNA damage stimulus
CTZ23_06420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ23_06425	COG1011	Hydrolase
CTZ23_06430	COG1218	3'(2'),5'-bisphosphate nucleotidase
CTZ23_06440	COG0268	Binds directly to 16S ribosomal RNA
CTZ23_06445	COG0702	epimerase
CTZ23_06450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ23_06465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ23_06495	COG0316	Belongs to the HesB IscA family
CTZ23_06500	COG0822	iron-sulfur transferase activity
CTZ23_06530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_06585	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ23_06605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_06620	COG0516	GMP reductase activity
CTZ23_06620	COG0517	IMP dehydrogenase activity
CTZ23_06650	COG0612	Peptidase, M16
CTZ23_06655	COG0552	protein localization to endoplasmic reticulum
CTZ23_06700	COG0693	protein deglycase activity
CTZ23_06710	COG1283	sodium-dependent phosphate transmembrane transporter activity
CTZ23_06720	COG1346	cytolysis
CTZ23_06730	COG0583	DNA-binding transcription factor activity
CTZ23_06760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_06765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ23_06770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ23_06795	COG1960	acyl-CoA dehydrogenase activity
CTZ23_06800	COG2207	Transcriptional regulator
CTZ23_06805	COG2814	Major facilitator Superfamily
CTZ23_06815	COG1271	oxidase subunit
CTZ23_06820	COG1294	oxidase, subunit
CTZ23_06830	COG1525	nuclease
CTZ23_06880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ23_06885	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ23_06900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_06910	COG2814	Major facilitator Superfamily
CTZ23_06930	COG1132	(ABC) transporter
CTZ23_06940	COG0668	transmembrane transport
CTZ23_06945	COG3122	Protein conserved in bacteria
CTZ23_06965	COG0640	Transcriptional regulator
CTZ23_06975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ23_06980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ23_06980	COG1116	anion transmembrane transporter activity
CTZ23_06990	COG2223	nitrite transmembrane transporter activity
CTZ23_06995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_07000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ23_07005	COG0243	molybdopterin cofactor binding
CTZ23_07015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ23_07030	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ23_07030	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ23_07035	COG0303	'Molybdopterin
CTZ23_07045	COG4149	molybdate abc transporter
CTZ23_07050	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ23_07055	COG0583	DNA-binding transcription factor activity
CTZ23_07075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_07080	COG0183	Belongs to the thiolase family
CTZ23_07085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_07090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ23_07095	COG3135	benzoate transporter
CTZ23_07100	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_07105	COG0543	2 iron, 2 sulfur cluster binding
CTZ23_07105	COG0633	Ferredoxin
CTZ23_07110	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ23_07115	COG4638	Rieske (2fe-2S)
CTZ23_07125	COG4829	muconolactone delta-isomerase
CTZ23_07130	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ23_07135	COG0583	DNA-binding transcription factor activity
CTZ23_07140	COG2814	Major facilitator Superfamily
CTZ23_07170	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_07180	COG2223	nitrite transmembrane transporter activity
CTZ23_07190	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CTZ23_07195	COG2116	formate transmembrane transporter activity
CTZ23_07200	COG0515	serine threonine protein kinase
CTZ23_07215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_07260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ23_07265	COG1309	transcriptional regulator
CTZ23_07270	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_07285	COG0745	RESPONSE REGULATOR receiver
CTZ23_07295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_07315	COG2026	Addiction module toxin, RelE StbE family
CTZ23_07330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CTZ23_07335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ23_07340	COG0730	response to heat
CTZ23_07390	COG2801	Transposase and inactivated derivatives
CTZ23_07480	COG0596	Alpha beta hydrolase
CTZ23_07515	COG0511	ligase activity, forming carbon-carbon bonds
CTZ23_07520	COG0439	Biotin carboxylase
CTZ23_07535	COG2814	Major facilitator Superfamily
CTZ23_07540	COG3038	cytochrome b561
CTZ23_07570	COG1058	Belongs to the CinA family
CTZ23_07570	COG1546	Belongs to the CinA family
CTZ23_07580	COG0372	Belongs to the citrate synthase family
CTZ23_07615	COG0542	response to heat
CTZ23_07620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ23_07645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CTZ23_07655	COG0569	domain protein
CTZ23_07660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ23_07680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ23_07690	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ23_07705	COG1294	oxidase, subunit
CTZ23_07710	COG4890	Cyd operon protein YbgT
CTZ23_07745	COG1960	acyl-CoA dehydrogenase activity
CTZ23_07750	COG1960	acyl-CoA dehydrogenase activity
CTZ23_07770	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ23_07775	COG2207	Transcriptional regulator
CTZ23_07780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_07785	COG0730	response to heat
CTZ23_07790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ23_07820	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_07830	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ23_07840	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_07855	COG0575	Belongs to the CDS family
CTZ23_07860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ23_07865	COG0233	cytoplasmic translational termination
CTZ23_07880	COG3852	Histidine kinase
CTZ23_07885	COG2204	response regulator
CTZ23_07895	COG0583	DNA-binding transcription factor activity
CTZ23_07900	COG0024	Methionine aminopeptidase
CTZ23_07925	COG1253	flavin adenine dinucleotide binding
CTZ23_07945	COG3385	transposase activity
CTZ23_07950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ23_07955	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ23_07970	COG2431	L-lysine efflux transmembrane transporter activity
CTZ23_07985	COG0776	regulation of translation
CTZ23_08005	COG0590	tRNA wobble adenosine to inosine editing
CTZ23_08015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CTZ23_08050	COG0084	hydrolase, TatD family'
CTZ23_08070	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ23_08075	COG1132	(ABC) transporter
CTZ23_08085	COG0811	peptide transport
CTZ23_08090	COG1475	DNA binding
CTZ23_08095	COG1192	Involved in chromosome partitioning
CTZ23_08105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ23_08110	COG3178	'Phosphotransferase
CTZ23_08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ23_08125	COG1923	regulation of RNA biosynthetic process
CTZ23_08135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ23_08140	COG0802	atpase or kinase
CTZ23_08165	COG2707	UPF0756 membrane protein
CTZ23_08175	COG0583	DNA-binding transcription factor activity
CTZ23_08180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_08190	COG1454	alcohol dehydrogenase
CTZ23_08210	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_08210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_08215	COG2353	YceI-like domain
CTZ23_08225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ23_08230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CTZ23_08270	COG1254	Belongs to the acylphosphatase family
CTZ23_08275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ23_08275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ23_08280	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTZ23_08300	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_08305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ23_08310	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ23_08315	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ23_08320	COG0183	Belongs to the thiolase family
CTZ23_08325	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_08330	COG1024	Enoyl-CoA hydratase
CTZ23_08335	COG1024	Enoyl-CoA hydratase
CTZ23_08340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ23_08345	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ23_08350	COG3396	Phenylacetate-CoA oxygenase
CTZ23_08355	COG3460	Phenylacetate-CoA oxygenase
CTZ23_08360	COG3396	Phenylacetate-CoA oxygenase
CTZ23_08365	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_08365	COG2030	dehydratase
CTZ23_08390	COG0783	Belongs to the Dps family
CTZ23_08475	COG5002	protein histidine kinase activity
CTZ23_08475	COG5001	Diguanylate cyclase
CTZ23_08485	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CTZ23_08505	COG4773	Receptor
CTZ23_08545	COG3328	transposase activity
CTZ23_08555	COG1401	restriction endodeoxyribonuclease activity
CTZ23_08565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ23_08590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_08595	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CTZ23_08640	COG2801	Transposase and inactivated derivatives
CTZ23_08665	COG0582	viral genome integration into host DNA
CTZ23_08670	COG0582	viral genome integration into host DNA
CTZ23_08680	COG3772	lysozyme
CTZ23_08760	COG3561	AntA/AntB antirepressor
CTZ23_08810	COG2369	cell adhesion
CTZ23_08815	COG3567	Phage-associated protein, HI1409 family
CTZ23_08820	COG5410	chromosome segregation
CTZ23_08840	COG2801	Transposase and inactivated derivatives
CTZ23_08930	COG5377	YqaJ viral recombinase family
CTZ23_08970	COG0204	Acyl-transferase
CTZ23_08995	COG0012	GTP binding
CTZ23_09005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ23_09020	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CTZ23_09030	COG0386	Belongs to the glutathione peroxidase family
CTZ23_09035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CTZ23_09040	COG0436	Aminotransferase
CTZ23_09045	COG2755	lipolytic protein G-D-S-L family
CTZ23_09045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CTZ23_09085	COG0515	serine threonine protein kinase
CTZ23_09085	COG2815	serine threonine protein kinase
CTZ23_09120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CTZ23_09125	COG1610	YqeY-like protein
CTZ23_09140	COG4783	chaperone-mediated protein folding
CTZ23_09205	COG0513	Belongs to the DEAD box helicase family
CTZ23_09225	COG2363	Small membrane protein
CTZ23_09245	COG0659	secondary active sulfate transmembrane transporter activity
CTZ23_09255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ23_09275	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_09280	COG1309	transcriptional regulator
CTZ23_09285	COG1960	acyl-CoA dehydrogenase activity
CTZ23_09290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ23_09295	COG1024	Enoyl-CoA hydratase
CTZ23_09300	COG0439	Biotin carboxylase
CTZ23_09315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ23_09330	COG0540	Belongs to the ATCase OTCase family
CTZ23_09350	COG1765	OsmC-like protein
CTZ23_09360	COG0667	Aldo Keto reductase
CTZ23_09375	COG0501	Belongs to the peptidase M48B family
CTZ23_09380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ23_09400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ23_09410	COG0527	aspartate kinase activity
CTZ23_09420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ23_09430	COG1215	transferase activity, transferring glycosyl groups
CTZ23_09440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ23_09445	COG2252	PERMEase
CTZ23_09480	COG0714	Associated with various cellular activities
CTZ23_09485	COG2879	small protein
CTZ23_09495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CTZ23_09500	COG1509	lysine 2,3-aminomutase activity
CTZ23_09535	COG1067	ATP-dependent peptidase activity
CTZ23_09540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ23_09545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ23_09550	COG0583	DNA-binding transcription factor activity
CTZ23_09560	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ23_09575	COG1686	Belongs to the peptidase S11 family
CTZ23_09580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ23_09585	COG3328	transposase activity
CTZ23_09590	COG1280	lysine exporter protein (LysE YggA)
CTZ23_09620	COG0616	signal peptide processing
CTZ23_09630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ23_09640	COG0573	inorganic phosphate transmembrane transporter activity
CTZ23_09650	COG0076	glutamate decarboxylase activity
CTZ23_09655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ23_09665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CTZ23_09690	COG1733	regulation of RNA biosynthetic process
CTZ23_09695	COG0702	epimerase
CTZ23_09725	COG0556	nucleotide-excision repair
CTZ23_09735	COG3706	GGDEF domain
CTZ23_09770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ23_09775	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ23_09785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ23_09790	COG0571	ribonuclease III activity
CTZ23_09800	COG0681	Belongs to the peptidase S26 family
CTZ23_09815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ23_09825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ23_09840	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ23_09850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ23_09865	COG4208	sulfate ABC transporter
CTZ23_09870	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ23_09875	COG0583	DNA-binding transcription factor activity
CTZ23_09885	COG4625	pathogenesis
CTZ23_09895	COG0602	queuosine metabolic process
CTZ23_09900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ23_09910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ23_09930	COG0583	DNA-binding transcription factor activity
CTZ23_09940	COG1056	cytidyltransferase-related domain
CTZ23_09940	COG1051	belongs to the nudix hydrolase family
CTZ23_09945	COG1024	Enoyl-CoA hydratase
CTZ23_09950	COG0778	Nitroreductase
CTZ23_09965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ23_09965	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ23_09985	COG2255	four-way junction helicase activity
CTZ23_09995	COG0824	Thioesterase
CTZ23_10015	COG0823	Involved in the tonB-independent uptake of proteins
CTZ23_10035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_10070	COG0628	permease
CTZ23_10075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CTZ23_10080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ23_10100	COG0658	competence protein
CTZ23_10100	COG2333	competence protein COMEC
CTZ23_10105	COG1136	(ABC) transporter
CTZ23_10110	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ23_10125	COG1671	Belongs to the UPF0178 family
CTZ23_10165	COG1280	lysine exporter protein (LysE YggA)
CTZ23_10170	COG1522	sequence-specific DNA binding
CTZ23_10180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ23_10195	COG0019	diaminopimelate decarboxylase activity
CTZ23_10205	COG1113	amino acid transport
CTZ23_10210	COG1115	amino acid carrier protein
CTZ23_10230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ23_10235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ23_10270	COG0583	DNA-binding transcription factor activity
CTZ23_10280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ23_10295	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ23_10355	COG3739	integral membrane protein
CTZ23_10360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CTZ23_10370	COG3385	transposase activity
CTZ23_10375	COG1741	Belongs to the pirin family
CTZ23_10380	COG3842	ATPase activity
CTZ23_10385	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ23_10415	COG0582	viral genome integration into host DNA
CTZ23_10445	COG2223	nitrite transmembrane transporter activity
CTZ23_10490	COG0798	PFAM Bile acid sodium symporter
CTZ23_10500	COG0640	Transcriptional regulator
CTZ23_10525	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CTZ23_10535	COG2184	nucleotidyltransferase activity
CTZ23_10580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ23_10585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CTZ23_10595	COG0037	tRNA processing
CTZ23_10600	COG1196	nuclear chromosome segregation
CTZ23_10600	COG0741	lytic transglycosylase activity
CTZ23_10600	COG0739	heme binding
CTZ23_10605	COG0501	Belongs to the peptidase M48B family
CTZ23_10615	COG2239	Acts as a magnesium transporter
CTZ23_10625	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ23_10650	COG1803	Methylglyoxal synthase
CTZ23_10650	COG1597	lipid kinase activity
CTZ23_10670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CTZ23_10705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ23_10720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ23_10725	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CTZ23_10730	COG1534	Rna-binding protein
CTZ23_10745	COG0505	Belongs to the CarA family
CTZ23_10780	COG0110	maltose O-acetyltransferase activity
CTZ23_10785	COG0589	response to stress
CTZ23_10795	COG2321	neutral zinc metallopeptidase
CTZ23_10800	COG2354	Protein conserved in bacteria
CTZ23_10825	COG2268	Band 7 protein
CTZ23_10835	COG1215	transferase activity, transferring glycosyl groups
CTZ23_10840	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_10840	COG0726	polysaccharide deacetylase
CTZ23_10850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CTZ23_10860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ23_10875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ23_10880	COG1053	succinate dehydrogenase
CTZ23_10885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ23_10890	COG2009	succinate dehydrogenase
CTZ23_10900	COG2072	flavoprotein involved in K transport
CTZ23_10905	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_10915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CTZ23_10920	COG0714	Associated with various cellular activities
CTZ23_10930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_10930	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ23_10960	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_10970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CTZ23_10985	COG0564	pseudouridine synthase activity
CTZ23_10995	COG0358	DNA primase activity
CTZ23_11010	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ23_11040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ23_11080	COG0586	Pfam SNARE associated Golgi protein
CTZ23_11115	COG0321	lipoyl(octanoyl) transferase activity
CTZ23_11135	COG0531	amino acid
CTZ23_11140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ23_11145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ23_11145	COG1648	precorrin-2 dehydrogenase activity
CTZ23_11150	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CTZ23_11160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ23_11185	COG0671	phosphoesterase, PA-phosphatase related
CTZ23_11190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_11200	COG1538	Outer membrane efflux protein
CTZ23_11205	COG0393	Putative heavy-metal-binding
CTZ23_11210	COG0393	Putative heavy-metal-binding
CTZ23_11215	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_11225	COG0525	valine-tRNA ligase activity
CTZ23_11250	COG2323	membrane
CTZ23_11260	COG0765	amino acid transport
CTZ23_11265	COG0765	amino acid transport
CTZ23_11270	COG1126	abc transporter atp-binding protein
CTZ23_11275	COG3338	carbonate dehydratase activity
CTZ23_11295	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ23_11310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ23_11315	COG2205	protein histidine kinase activity
CTZ23_11320	COG0745	RESPONSE REGULATOR receiver
CTZ23_11335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ23_11340	COG1652	LysM domain
CTZ23_11350	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ23_11360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CTZ23_11365	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ23_11370	COG3101	peptidyl-lysine hydroxylation
CTZ23_11375	COG0009	L-threonylcarbamoyladenylate synthase
CTZ23_11385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ23_11390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ23_11405	COG4106	trans-aconitate 2-methyltransferase activity
CTZ23_11420	COG0596	Alpha beta hydrolase
CTZ23_11420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ23_11420	COG2226	methyltransferase
CTZ23_11425	COG2193	ferroxidase activity
CTZ23_11430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CTZ23_11435	COG3115	cell septum assembly
CTZ23_11440	COG1196	nuclear chromosome segregation
CTZ23_11450	COG0730	response to heat
CTZ23_11470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ23_11485	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CTZ23_11535	COG3328	transposase activity
CTZ23_11555	COG0628	permease
CTZ23_11565	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ23_11585	COG0564	pseudouridine synthase activity
CTZ23_11590	COG0346	lactoylglutathione lyase activity
CTZ23_11640	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ23_11670	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ23_11670	COG0726	polysaccharide deacetylase
CTZ23_11685	COG3328	transposase activity
CTZ23_11715	COG3177	Filamentation induced by cAMP protein fic
CTZ23_11740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ23_11745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CTZ23_11770	COG0640	Transcriptional regulator
CTZ23_11785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CTZ23_11795	COG0745	RESPONSE REGULATOR receiver
CTZ23_11800	COG0642	Histidine kinase
CTZ23_11880	COG0582	viral genome integration into host DNA
CTZ23_11890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ23_11895	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ23_11915	COG0420	3'-5' exonuclease activity
CTZ23_11945	COG0735	belongs to the Fur family
CTZ23_11950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_11955	COG2914	Belongs to the UPF0125 (RnfH) family
CTZ23_11970	COG0121	glutamine amidotransferase
CTZ23_11985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ23_12000	COG0756	dUTP diphosphatase activity
CTZ23_12005	COG0210	DNA helicase
CTZ23_12010	COG2885	chlorophyll binding
CTZ23_12015	COG0204	Acyl-transferase
CTZ23_12025	COG0850	regulation of cytokinetic process
CTZ23_12030	COG2894	cell division
CTZ23_12045	COG1674	ftsk spoiiie
CTZ23_12045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ23_12050	COG0492	ferredoxin-NADP+ reductase activity
CTZ23_12055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ23_12060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CTZ23_12065	COG0456	acetyltransferase
CTZ23_12090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CTZ23_12110	COG1113	amino acid transport
CTZ23_12115	COG0251	oxidation-reduction process
CTZ23_12130	COG1522	sequence-specific DNA binding
CTZ23_12140	COG0351	phosphomethylpyrimidine kinase
CTZ23_12140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ23_12140	COG0352	thiamine-phosphate diphosphorylase activity
CTZ23_12155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ23_12160	COG2076	Multidrug Resistance protein
CTZ23_12175	COG2132	Multicopper oxidase
CTZ23_12185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ23_12200	COG4269	membrane
CTZ23_12220	COG1968	undecaprenyl-diphosphatase activity
CTZ23_12225	COG1214	PFAM Peptidase M22, glycoprotease
CTZ23_12235	COG0494	nUDIX hydrolase
CTZ23_12285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ23_12290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ23_12380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ23_12425	COG0037	tRNA processing
CTZ23_12435	COG0248	Ppx GppA phosphatase
CTZ23_12460	COG0072	phenylalanine-tRNA ligase activity
CTZ23_12480	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CTZ23_12495	COG1238	metal cluster binding
CTZ23_12500	COG0625	glutathione transferase activity
CTZ23_12525	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_12530	COG3028	Belongs to the UPF0307 family
CTZ23_12540	COG1660	Displays ATPase and GTPase activities
CTZ23_12555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ23_12560	COG0617	tRNA 3'-terminal CCA addition
CTZ23_12565	COG1555	photosystem II stabilization
CTZ23_12570	COG3956	TIGRFAM MazG family protein
CTZ23_12585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ23_12595	COG0124	histidyl-tRNA synthetase
CTZ23_12625	COG2975	iron-sulfur cluster assembly
CTZ23_12665	COG0440	acetolactate synthase activity
CTZ23_12670	COG0028	Belongs to the TPP enzyme family
CTZ23_12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_12700	COG0577	efflux transmembrane transporter activity
CTZ23_12700	COG1136	(ABC) transporter
CTZ23_12705	COG1538	Outer membrane efflux protein
CTZ23_12720	COG3209	COG3209 Rhs family protein
CTZ23_12740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ23_12745	COG1162	GTPase activity
CTZ23_12755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ23_12765	COG3385	transposase activity
CTZ23_12770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ23_12780	COG3781	membrane
CTZ23_12795	COG2350	Protein conserved in bacteria
CTZ23_12815	COG1666	GTP binding
CTZ23_12825	COG1607	acyl-coa hydrolase
CTZ23_12840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ23_12840	COG3453	Protein conserved in bacteria
CTZ23_12890	COG1183	phosphatidylcholine synthase activity
CTZ23_12895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ23_12935	COG3385	transposase activity
CTZ23_12950	COG1196	nuclear chromosome segregation
CTZ23_12950	COG0741	lytic transglycosylase activity
CTZ23_12950	COG0739	heme binding
CTZ23_12955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CTZ23_12960	COG1702	phosphate starvation-inducible protein PhoH
CTZ23_13010	COG1295	ribonuclease BN
CTZ23_13040	COG0788	formyltetrahydrofolate deformylase activity
CTZ23_13055	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CTZ23_13060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CTZ23_13065	COG4651	solute:proton antiporter activity
CTZ23_13065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ23_13080	COG0724	RNA recognition motif
CTZ23_13085	COG0210	DNA helicase
CTZ23_13095	COG1929	Belongs to the glycerate kinase type-1 family
CTZ23_13135	COG1560	Kdo2-lipid A biosynthetic process
CTZ23_13185	COG0473	3-isopropylmalate dehydrogenase activity
CTZ23_13200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CTZ23_13220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ23_13235	COG0494	nUDIX hydrolase
CTZ23_13255	COG1960	acyl-CoA dehydrogenase activity
CTZ23_13265	COG0753	catalase activity
CTZ23_13280	COG0583	DNA-binding transcription factor activity
CTZ23_13285	COG0546	phosphoglycolate phosphatase activity
CTZ23_13300	COG1530	ribonuclease E activity
CTZ23_13330	COG1983	PspC domain protein
CTZ23_13345	COG0751	glycine-tRNA ligase activity
CTZ23_13375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CTZ23_13390	COG2226	methyltransferase
CTZ23_13400	COG0493	'glutamate synthase
CTZ23_13400	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ23_13410	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ23_13420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ23_13435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ23_13445	COG0644	oxidoreductase
CTZ23_13445	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ23_13460	COG3501	Rhs element vgr protein
CTZ23_13465	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ23_13470	COG4535	Mg2 and Co2 transporter CorC
CTZ23_13475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CTZ23_13495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ23_13505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ23_13515	COG0789	Transcriptional regulator
CTZ23_13520	COG2841	Protein conserved in bacteria
CTZ23_13535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CTZ23_13540	COG0675	Transposase, IS605 OrfB family
CTZ23_13545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ23_13550	COG1074	ATP-dependent DNA helicase activity
CTZ23_13555	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ23_13585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ23_13595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ23_13610	COG2111	Na H antiporter
CTZ23_13610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ23_13615	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ23_13620	COG0651	ATP synthesis coupled electron transport
CTZ23_13630	COG2212	antiporter activity
CTZ23_13640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CTZ23_13650	COG0195	Participates in both transcription termination and antitermination
CTZ23_13655	COG0779	Required for maturation of 30S ribosomal subunits
CTZ23_13705	COG0237	dephospho-CoA kinase activity
CTZ23_13715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ23_13720	COG3123	guanosine phosphorylase activity
CTZ23_13725	COG0497	DNA recombination
CTZ23_13735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ23_13750	COG1132	(ABC) transporter
CTZ23_13755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ23_13785	COG1024	Enoyl-CoA hydratase
CTZ23_13785	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ23_13805	COG2233	PERMEase
CTZ23_13815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ23_13840	COG0326	Molecular chaperone. Has ATPase activity
CTZ23_13855	COG2056	Na+-H+ antiporter family
CTZ23_13875	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CTZ23_13880	COG0085	RNA polymerase activity
CTZ23_13895	COG0081	regulation of translation
CTZ23_13980	COG0824	Thioesterase
CTZ23_14000	COG0181	hydroxymethylbilane synthase activity
CTZ23_14010	COG3275	phosphorelay sensor kinase activity
CTZ23_14045	COG0494	nUDIX hydrolase
CTZ23_14050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ23_14055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ23_14060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ23_14070	COG0772	Belongs to the SEDS family
CTZ23_14095	COG4974	Belongs to the 'phage' integrase family
CTZ23_14110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ23_14120	COG2197	response regulator
CTZ23_14135	COG0793	Belongs to the peptidase S41A family
CTZ23_14140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ23_14145	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_14150	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ23_14175	COG0586	Pfam SNARE associated Golgi protein
CTZ23_14190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_14190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ23_14200	COG0004	ammonium transporteR
CTZ23_14205	COG0347	Belongs to the P(II) protein family
CTZ23_14265	COG3293	Transposase
CTZ23_14290	COG3293	Transposase
CTZ23_14305	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_14310	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CTZ23_14320	COG2826	transposase and inactivated derivatives, IS30 family
CTZ23_14360	COG0606	chelatase, subunit chli
CTZ23_14375	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ23_14390	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ23_14400	COG0477	Major facilitator Superfamily
CTZ23_14405	COG2860	membrane
CTZ23_14415	COG1253	flavin adenine dinucleotide binding
CTZ23_14435	COG2814	Major facilitator Superfamily
CTZ23_14450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ23_14470	COG2814	Major facilitator Superfamily
CTZ23_14520	COG0758	DNA mediated transformation
CTZ23_14535	COG0697	spore germination
CTZ23_14545	COG0386	Belongs to the glutathione peroxidase family
CTZ23_14580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CTZ23_14590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CTZ23_14630	COG1121	(ABC) transporter
CTZ23_14635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ23_14645	COG2837	iron assimilation
CTZ23_14665	COG3501	Rhs element vgr protein
CTZ23_14670	COG0281	malic enzyme
CTZ23_14710	COG3706	GGDEF domain
CTZ23_14710	COG0745	RESPONSE REGULATOR receiver
CTZ23_14715	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ23_14715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ23_14720	COG2259	Doxx family
CTZ23_14725	COG0586	Pfam SNARE associated Golgi protein
CTZ23_14740	COG1192	Involved in chromosome partitioning
CTZ23_14750	COG0271	Belongs to the BolA IbaG family
CTZ23_14775	COG3550	peptidyl-serine autophosphorylation
CTZ23_14780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CTZ23_14805	COG4628	conserved protein (DUF2132)
CTZ23_14815	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CTZ23_14830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ23_14840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ23_14860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ23_14870	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTZ23_14880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ23_14900	COG1086	Polysaccharide biosynthesis protein
CTZ23_14915	COG0110	maltose O-acetyltransferase activity
CTZ23_14940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ23_14995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ23_15000	COG1309	transcriptional regulator
CTZ23_15010	COG2233	PERMEase
CTZ23_15025	COG0129	dihydroxy-acid dehydratase activity
CTZ23_15040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CTZ23_15050	COG0733	neurotransmitter:sodium symporter activity
CTZ23_15055	COG1012	belongs to the aldehyde dehydrogenase family
CTZ23_15065	COG3385	transposase activity
CTZ23_15070	COG2814	Major facilitator Superfamily
CTZ23_15100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ23_15145	COG2951	lytic endotransglycosylase activity
CTZ23_15155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ23_15175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ23_15190	COG2388	GCN5-related N-acetyl-transferase
CTZ23_15200	COG0861	Integral membrane protein TerC family
CTZ23_15205	COG0402	S-adenosylhomocysteine deaminase activity
CTZ23_15215	COG0675	Transposase, IS605 OrfB family
CTZ23_15225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ23_15230	COG1230	cation diffusion facilitator family transporter
CTZ23_15255	COG0706	membrane insertase activity
CTZ23_15260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CTZ23_15265	COG0594	ribonuclease P activity
CTZ23_15270	COG0230	Belongs to the bacterial ribosomal protein bL34 family