locus-tag	class	description
F9230_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F9230_00010	COG0592	DNA-directed DNA polymerase activity
F9230_00020	COG0187	DNA topoisomerase II activity
F9230_00030	COG0488	(ABC) transporter
F9230_00090	COG0657	acetylesterase activity
F9230_00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9230_00130	COG2814	Major facilitator Superfamily
F9230_00140	COG0733	neurotransmitter:sodium symporter activity
F9230_00185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9230_00185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F9230_00200	COG0129	dihydroxy-acid dehydratase activity
F9230_00210	COG4774	siderophore transport
F9230_00220	COG0583	DNA-binding transcription factor activity
F9230_00225	COG2233	PERMEase
F9230_00235	COG1309	transcriptional regulator
F9230_00255	COG0484	heat shock protein binding
F9230_00265	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F9230_00280	COG0436	Aminotransferase
F9230_00285	COG1064	alcohol dehydrogenase
F9230_00290	COG2818	Glycosylase
F9230_00320	COG5487	UPF0391 membrane protein
F9230_00325	COG2983	Belongs to the UPF0260 family
F9230_00330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9230_00350	COG4160	amino acid transport
F9230_00355	COG4215	(ABC) transporter
F9230_00380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9230_00385	COG1335	isochorismatase
F9230_00390	COG0385	Bile acid
F9230_00460	COG0534	Mate efflux family protein
F9230_00465	COG0436	Aminotransferase
F9230_00470	COG2733	membrane
F9230_00485	COG2918	glutathione biosynthetic process
F9230_00490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F9230_00500	COG3150	esterase
F9230_00585	COG3706	GGDEF domain
F9230_00590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F9230_00605	COG1393	Belongs to the ArsC family
F9230_00610	COG0708	Exodeoxyribonuclease III
F9230_00620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9230_00635	COG1846	Transcriptional regulator
F9230_00640	COG0386	Belongs to the glutathione peroxidase family
F9230_00645	COG0189	ligase activity
F9230_00655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9230_00665	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9230_00675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F9230_00705	COG2119	membrane
F9230_00710	COG0426	domain, Protein
F9230_00710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_00735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9230_00760	COG1902	pentaerythritol trinitrate reductase activity
F9230_00765	COG1519	Transferase
F9230_00770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9230_00775	COG0668	transmembrane transport
F9230_00780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_00790	COG0579	oxidoreductase
F9230_00800	COG0307	riboflavin synthase, alpha
F9230_00820	COG0431	NADPH-dependent FMN reductase
F9230_00835	COG0784	Response regulator, receiver
F9230_00835	COG2205	protein histidine kinase activity
F9230_00840	COG3162	membrane
F9230_00845	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9230_00855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9230_00865	COG3706	GGDEF domain
F9230_00885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9230_00885	COG0352	thiamine-phosphate diphosphorylase activity
F9230_00885	COG0351	phosphomethylpyrimidine kinase
F9230_00895	COG2814	Major facilitator Superfamily
F9230_00900	COG0629	single-stranded DNA binding
F9230_00910	COG0583	DNA-binding transcription factor activity
F9230_00915	COG1301	dicarboxylic acid transport
F9230_00935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_00950	COG1335	isochorismatase
F9230_00960	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
F9230_01020	COG0582	viral genome integration into host DNA
F9230_01050	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F9230_01075	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9230_01080	COG1278	Cold shock
F9230_01095	COG0531	amino acid
F9230_01100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9230_01135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9230_01170	COG0427	acetyl-CoA hydrolase
F9230_01200	COG4221	oxidoreductase activity
F9230_01205	COG2873	o-acetylhomoserine
F9230_01210	COG0488	(ABC) transporter
F9230_01230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_01245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9230_01265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9230_01270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9230_01280	COG2226	methyltransferase
F9230_01330	COG0067	glutamate synthase
F9230_01330	COG0069	glutamate synthase activity
F9230_01330	COG0070	glutamate synthase
F9230_01335	COG0493	'glutamate synthase
F9230_01345	COG1704	LemA family
F9230_01350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F9230_01395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_01400	COG1758	RNA polymerase activity
F9230_01405	COG0194	GDP metabolic process
F9230_01415	COG4969	Belongs to the N-Me-Phe pilin family
F9230_01450	COG0228	four-way junction DNA binding
F9230_01455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F9230_01465	COG0335	large ribosomal subunit rRNA binding
F9230_01480	COG5380	lipid catabolic process
F9230_01485	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9230_01505	COG5006	permease, DMT superfamily
F9230_01510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9230_01515	COG0277	FAD linked oxidase domain protein
F9230_01525	COG2197	response regulator
F9230_01530	COG0477	Major facilitator Superfamily
F9230_01540	COG2814	Major facilitator Superfamily
F9230_01545	COG1289	transmembrane transporter activity
F9230_01550	COG2032	superoxide dismutase activity
F9230_01555	COG0628	permease
F9230_01560	COG1192	Involved in chromosome partitioning
F9230_01570	COG2226	methyltransferase
F9230_01585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F9230_01590	COG0254	rRNA binding
F9230_01595	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9230_01605	COG0534	Mate efflux family protein
F9230_01615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9230_01635	COG1960	acyl-CoA dehydrogenase activity
F9230_01655	COG0408	coproporphyrinogen oxidase activity
F9230_01660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9230_01680	COG0513	Belongs to the DEAD box helicase family
F9230_01685	COG1127	ABC transporter
F9230_01690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9230_01695	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9230_01700	COG2854	intermembrane phospholipid transfer
F9230_01710	COG0598	Magnesium transport protein CorA
F9230_01720	COG0494	nUDIX hydrolase
F9230_01725	COG1040	competence protein
F9230_01730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9230_01755	COG2937	Belongs to the GPAT DAPAT family
F9230_01760	COG1946	Acyl-CoA thioesterase
F9230_01765	COG1301	dicarboxylic acid transport
F9230_01780	COG1959	2 iron, 2 sulfur cluster binding
F9230_01790	COG0433	COG0433 Predicted ATPase
F9230_01810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F9230_01815	COG0088	Forms part of the polypeptide exit tunnel
F9230_01830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F9230_01880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F9230_01885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F9230_01895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F9230_01920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9230_01935	COG0202	RNA polymerase activity
F9230_01940	COG0203	ribosomal protein L17
F9230_01945	COG2072	flavoprotein involved in K transport
F9230_01955	COG1960	acyl-CoA dehydrogenase activity
F9230_01960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9230_01995	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F9230_02000	COG0339	signal peptide processing
F9230_02005	COG2720	vancomycin resistance protein
F9230_02010	COG0557	exoribonuclease II activity
F9230_02040	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9230_02055	COG1295	ribonuclease BN
F9230_02095	COG4773	Receptor
F9230_02105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F9230_02110	COG1702	phosphate starvation-inducible protein PhoH
F9230_02115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F9230_02120	COG0741	lytic transglycosylase activity
F9230_02120	COG1196	nuclear chromosome segregation
F9230_02120	COG0739	heme binding
F9230_02130	COG0039	L-malate dehydrogenase activity
F9230_02155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9230_02160	COG1183	phosphatidylcholine synthase activity
F9230_02220	COG1607	acyl-coa hydrolase
F9230_02235	COG1666	GTP binding
F9230_02255	COG2350	Protein conserved in bacteria
F9230_02265	COG0613	PHP domain protein
F9230_02270	COG3781	membrane
F9230_02280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9230_02305	COG1162	GTPase activity
F9230_02310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F9230_02335	COG1538	Outer membrane efflux protein
F9230_02340	COG0577	efflux transmembrane transporter activity
F9230_02340	COG1136	(ABC) transporter
F9230_02345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_02370	COG0028	Belongs to the TPP enzyme family
F9230_02375	COG0440	acetolactate synthase activity
F9230_02435	COG1426	Protein conserved in bacteria
F9230_02455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_02480	COG1862	Preprotein translocase
F9230_02490	COG1704	LemA family
F9230_02500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F9230_02510	COG5002	protein histidine kinase activity
F9230_02515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9230_02545	COG0438	transferase activity, transferring glycosyl groups
F9230_02565	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F9230_02580	COG0463	Glycosyl transferase, family 2
F9230_02610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F9230_02640	COG3223	Belongs to the PsiE family
F9230_02645	COG1960	acyl-CoA dehydrogenase activity
F9230_02650	COG1960	acyl-CoA dehydrogenase activity
F9230_02660	COG2205	protein histidine kinase activity
F9230_02665	COG0745	RESPONSE REGULATOR receiver
F9230_02670	COG1113	amino acid transport
F9230_02680	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F9230_02700	COG2096	Adenosyltransferase
F9230_02705	COG4206	TonB-dependent receptor
F9230_02730	COG3083	sulfuric ester hydrolase activity
F9230_02760	COG0285	dihydrofolate synthase activity
F9230_02780	COG0450	alkyl hydroperoxide reductase
F9230_02800	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F9230_02805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F9230_02835	COG2199	diguanylate cyclase activity
F9230_02870	COG2814	Major facilitator Superfamily
F9230_02885	COG0693	protein deglycase activity
F9230_02910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F9230_02920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9230_02970	COG0494	nUDIX hydrolase
F9230_02975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9230_02980	COG1214	PFAM Peptidase M22, glycoprotease
F9230_02985	COG1968	undecaprenyl-diphosphatase activity
F9230_03020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9230_03030	COG2132	Multicopper oxidase
F9230_03055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9230_03065	COG0352	thiamine-phosphate diphosphorylase activity
F9230_03065	COG0351	phosphomethylpyrimidine kinase
F9230_03065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9230_03095	COG0251	oxidation-reduction process
F9230_03100	COG1113	amino acid transport
F9230_03110	COG1981	membrane
F9230_03125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F9230_03170	COG0456	acetyltransferase
F9230_03180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F9230_03185	COG0492	ferredoxin-NADP+ reductase activity
F9230_03190	COG0531	amino acid
F9230_03190	COG1674	ftsk spoiiie
F9230_03205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F9230_03210	COG2894	cell division
F9230_03215	COG0850	regulation of cytokinetic process
F9230_03225	COG0204	Acyl-transferase
F9230_03230	COG2885	chlorophyll binding
F9230_03235	COG0210	DNA helicase
F9230_03240	COG0756	dUTP diphosphatase activity
F9230_03255	COG0121	glutamine amidotransferase
F9230_03270	COG2914	Belongs to the UPF0125 (RnfH) family
F9230_03275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_03280	COG0735	belongs to the Fur family
F9230_03310	COG0420	3'-5' exonuclease activity
F9230_03315	COG3706	GGDEF domain
F9230_03315	COG4251	negative regulation of phosphorylation
F9230_03315	COG5001	Diguanylate cyclase
F9230_03315	COG2203	Gaf domain
F9230_03325	COG1090	epimerase
F9230_03340	COG2050	protein possibly involved in aromatic compounds catabolism
F9230_03345	COG1566	PFAM secretion protein HlyD family protein
F9230_03350	COG2814	Major facilitator Superfamily
F9230_03355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F9230_03580	COG4695	Portal protein
F9230_03585	COG0582	viral genome integration into host DNA
F9230_03640	COG1215	transferase activity, transferring glycosyl groups
F9230_03655	COG1968	undecaprenyl-diphosphatase activity
F9230_03660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F9230_03665	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F9230_03670	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F9230_03675	COG2205	protein histidine kinase activity
F9230_03680	COG0745	RESPONSE REGULATOR receiver
F9230_03685	COG0697	spore germination
F9230_03690	COG2721	sulfolactate sulfo-lyase activity
F9230_03695	COG2271	Major facilitator Superfamily
F9230_03705	COG1012	belongs to the aldehyde dehydrogenase family
F9230_03715	COG2186	Transcriptional regulator
F9230_03725	COG1802	Transcriptional regulator
F9230_03780	COG2814	Major facilitator Superfamily
F9230_03785	COG0583	DNA-binding transcription factor activity
F9230_03795	COG1522	sequence-specific DNA binding
F9230_03805	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_03825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_03835	COG1294	oxidase, subunit
F9230_03840	COG1271	oxidase subunit
F9230_03855	COG1113	amino acid transport
F9230_03865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9230_03870	COG1012	belongs to the aldehyde dehydrogenase family
F9230_03880	COG1522	sequence-specific DNA binding
F9230_03885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9230_03895	COG3138	arginine N-succinyltransferase
F9230_03900	COG1012	belongs to the aldehyde dehydrogenase family
F9230_03905	COG3724	N-succinylarginine dihydrolase activity
F9230_03915	COG1113	amino acid transport
F9230_03940	COG1414	Transcriptional regulator
F9230_03945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9230_03950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_03955	COG0183	Belongs to the thiolase family
F9230_03960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9230_03965	COG0596	Alpha beta hydrolase
F9230_03970	COG2271	Major facilitator Superfamily
F9230_03975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9230_03980	COG3485	protocatechuate 3,4-dioxygenase
F9230_03985	COG3485	protocatechuate 3,4-dioxygenase
F9230_03990	COG0710	3-dehydroquinate dehydratase activity
F9230_03995	COG3420	alginic acid biosynthetic process
F9230_04000	COG3659	wide pore channel activity
F9230_04005	COG4993	Dehydrogenase
F9230_04010	COG4772	TonB-dependent receptor
F9230_04020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_04030	COG0583	DNA-binding transcription factor activity
F9230_04035	COG2610	gluconate transmembrane transporter activity
F9230_04040	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_04050	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F9230_04085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9230_04095	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9230_04100	COG1077	Cell shape determining protein MreB Mrl
F9230_04105	COG1792	Involved in formation and maintenance of cell shape
F9230_04110	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F9230_04115	COG0424	maF-like protein
F9230_04125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9230_04175	COG0640	Transcriptional regulator
F9230_04185	COG0798	PFAM Bile acid sodium symporter
F9230_04190	COG0431	NADPH-dependent FMN reductase
F9230_04195	COG2072	flavoprotein involved in K transport
F9230_04205	COG0625	glutathione transferase activity
F9230_04225	COG1113	amino acid transport
F9230_04235	COG0583	DNA-binding transcription factor activity
F9230_04240	COG0006	proline dipeptidase activity
F9230_04255	COG1012	belongs to the aldehyde dehydrogenase family
F9230_04260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_04265	COG0723	plastoquinol--plastocyanin reductase activity
F9230_04265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F9230_04290	COG0697	spore germination
F9230_04305	COG0582	viral genome integration into host DNA
F9230_04315	COG1113	amino acid transport
F9230_04320	COG2828	Protein conserved in bacteria
F9230_04325	COG0142	geranyltranstransferase activity
F9230_04340	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9230_04365	COG0745	RESPONSE REGULATOR receiver
F9230_04370	COG0642	Histidine kinase
F9230_04385	COG0004	ammonium transporteR
F9230_04395	COG1126	abc transporter atp-binding protein
F9230_04400	COG0765	amino acid transport
F9230_04405	COG0765	amino acid transport
F9230_04425	COG0668	transmembrane transport
F9230_04435	COG2081	HI0933 family
F9230_04440	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F9230_04470	COG4716	Myosin-crossreactive antigen
F9230_04505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_04505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_04530	COG0489	protein tyrosine kinase activity
F9230_04545	COG2358	TRAP transporter, solute receptor (TAXI family
F9230_04615	COG0840	transmembrane signaling receptor activity
F9230_04620	COG0643	Histidine kinase
F9230_04620	COG0784	Response regulator, receiver
F9230_04620	COG2198	Histidine kinase
F9230_04630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F9230_04645	COG2832	Protein of unknown function (DUF454)
F9230_04715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F9230_04725	COG1289	transmembrane transporter activity
F9230_04730	COG2814	Major facilitator Superfamily
F9230_04745	COG0786	glutamate:sodium symporter activity
F9230_04750	COG1115	amino acid carrier protein
F9230_04760	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9230_04765	COG1607	acyl-coa hydrolase
F9230_04775	COG0523	cobalamin synthesis protein
F9230_04780	COG4681	YaeQ
F9230_04790	COG2203	Gaf domain
F9230_04790	COG2199	diguanylate cyclase activity
F9230_04835	COG0477	Major facilitator Superfamily
F9230_04840	COG0242	peptide deformylase activity
F9230_04845	COG2207	Transcriptional regulator
F9230_04850	COG2223	nitrite transmembrane transporter activity
F9230_04880	COG0306	phosphate transporter
F9230_04900	COG4771	TonB-dependent receptor
F9230_04925	COG4181	ATPase activity
F9230_04930	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F9230_04950	COG0583	DNA-binding transcription factor activity
F9230_04960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_04965	COG1773	rubredoxin
F9230_04970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F9230_05010	COG1695	Transcriptional regulator
F9230_05025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9230_05025	COG3321	synthase
F9230_05025	COG4221	oxidoreductase activity
F9230_05025	COG0604	alcohol dehydrogenase
F9230_05065	COG0477	Major facilitator Superfamily
F9230_05085	COG1597	lipid kinase activity
F9230_05175	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_05180	COG1063	alcohol dehydrogenase
F9230_05215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F9230_05220	COG1335	isochorismatase
F9230_05240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9230_05255	COG2323	membrane
F9230_05295	COG2223	nitrite transmembrane transporter activity
F9230_05300	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F9230_05305	COG1877	trehalose-phosphatase activity
F9230_05320	COG1570	exodeoxyribonuclease VII activity
F9230_05365	COG0582	viral genome integration into host DNA
F9230_05375	COG0641	radical SAM
F9230_05380	COG3119	arylsulfatase activity
F9230_05405	COG0742	ribosomal rna small subunit methyltransferase
F9230_05410	COG0768	penicillin binding
F9230_05435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9230_05440	COG2878	Part of a membrane complex involved in electron transport
F9230_05445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9230_05455	COG3384	dioxygenase
F9230_05465	COG2234	aminopeptidase activity
F9230_05480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9230_05490	COG2217	Heavy metal translocating P-type atpase
F9230_05495	COG0583	DNA-binding transcription factor activity
F9230_05500	COG1914	H( )-stimulated, divalent metal cation uptake system
F9230_05520	COG4770	biotin carboxylase activity
F9230_05525	COG3284	Transcriptional regulator
F9230_05545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9230_05550	COG0235	Class ii aldolase
F9230_05555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_05580	COG0006	proline dipeptidase activity
F9230_05605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9230_05610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9230_05630	COG2915	High frequency lysogenization protein hflD homolog
F9230_05650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9230_05655	COG1686	Belongs to the peptidase S11 family
F9230_05685	COG0753	catalase activity
F9230_05705	COG0583	DNA-binding transcription factor activity
F9230_05725	COG0657	acetylesterase activity
F9230_05740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9230_05745	COG1388	LysM domain
F9230_05745	COG0741	lytic transglycosylase activity
F9230_05750	COG4166	transmembrane transport
F9230_05755	COG4174	ABC transporter (Permease)
F9230_05760	COG4239	(ABC) transporter, permease
F9230_05765	COG4172	Belongs to the ABC transporter superfamily
F9230_05780	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F9230_05805	COG0833	amino acid
F9230_05815	COG0833	amino acid
F9230_05825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9230_05830	COG0418	dihydroorotase activity
F9230_05835	COG5001	Diguanylate cyclase
F9230_05835	COG4251	negative regulation of phosphorylation
F9230_05835	COG2203	Gaf domain
F9230_05835	COG3706	GGDEF domain
F9230_05850	COG2186	Transcriptional regulator
F9230_05860	COG0277	FAD linked oxidase domain protein
F9230_05865	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9230_05865	COG1902	pentaerythritol trinitrate reductase activity
F9230_05875	COG0583	DNA-binding transcription factor activity
F9230_05895	COG1012	belongs to the aldehyde dehydrogenase family
F9230_05900	COG0531	amino acid
F9230_05905	COG2957	Belongs to the agmatine deiminase family
F9230_05930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_05935	COG1960	acyl-CoA dehydrogenase activity
F9230_05940	COG1024	Enoyl-CoA hydratase
F9230_05990	COG1773	rubredoxin
F9230_05995	COG3119	arylsulfatase activity
F9230_06010	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F9230_06020	COG0280	phosphate acetyltransferase
F9230_06020	COG0281	malic enzyme
F9230_06025	COG1716	ATPase activity
F9230_06025	COG5001	Diguanylate cyclase
F9230_06030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9230_06035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F9230_06040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F9230_06080	COG1960	acyl-CoA dehydrogenase activity
F9230_06085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9230_06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_06100	COG1671	Belongs to the UPF0178 family
F9230_06115	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9230_06120	COG1136	(ABC) transporter
F9230_06125	COG0658	competence protein
F9230_06125	COG2333	competence protein COMEC
F9230_06145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9230_06150	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F9230_06155	COG0628	permease
F9230_06160	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F9230_06195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9230_06215	COG0823	Involved in the tonB-independent uptake of proteins
F9230_06235	COG0824	Thioesterase
F9230_06250	COG2255	four-way junction helicase activity
F9230_06255	COG0632	four-way junction helicase activity
F9230_06265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9230_06265	COG0047	phosphoribosylformylglycinamidine synthase activity
F9230_06280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9230_06280	COG3323	Protein of unknown function (DUF1653)
F9230_06290	COG0778	Nitroreductase
F9230_06295	COG1024	Enoyl-CoA hydratase
F9230_06300	COG1051	belongs to the nudix hydrolase family
F9230_06300	COG1056	cytidyltransferase-related domain
F9230_06305	COG2353	YceI-like domain
F9230_06310	COG0583	DNA-binding transcription factor activity
F9230_06320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9230_06335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F9230_06340	COG0602	queuosine metabolic process
F9230_06360	COG0583	DNA-binding transcription factor activity
F9230_06365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F9230_06370	COG4208	sulfate ABC transporter
F9230_06385	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9230_06395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9230_06415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9230_06430	COG0681	Belongs to the peptidase S26 family
F9230_06440	COG0571	ribonuclease III activity
F9230_06445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9230_06455	COG1381	Involved in DNA repair and RecF pathway recombination
F9230_06460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9230_06495	COG0436	Aminotransferase
F9230_06505	COG2199	diguanylate cyclase activity
F9230_06520	COG0556	nucleotide-excision repair
F9230_06550	COG0702	epimerase
F9230_06555	COG1733	regulation of RNA biosynthetic process
F9230_06565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F9230_06570	COG0671	phosphoesterase, PA-phosphatase related
F9230_06575	COG4772	TonB-dependent receptor
F9230_06585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9230_06590	COG0076	glutamate decarboxylase activity
F9230_06600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9230_06605	COG0573	inorganic phosphate transmembrane transporter activity
F9230_06615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9230_06620	COG0616	signal peptide processing
F9230_06625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9230_06630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F9230_06635	COG1067	ATP-dependent peptidase activity
F9230_06655	COG0254	rRNA binding
F9230_06675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F9230_06680	COG1966	Carbon starvation protein
F9230_06685	COG2879	small protein
F9230_06690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F9230_06695	COG0714	Associated with various cellular activities
F9230_06805	COG3220	belongs to the UPF0276 family
F9230_06815	COG1595	DNA-templated transcription, initiation
F9230_06835	COG2199	diguanylate cyclase activity
F9230_06835	COG2203	Gaf domain
F9230_06855	COG2351	hydroxyisourate hydrolase activity
F9230_06870	COG3046	protein related to deoxyribodipyrimidine photolyase
F9230_06875	COG2816	NAD+ diphosphatase activity
F9230_06900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9230_06915	COG0642	Histidine kinase
F9230_06950	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9230_06955	COG0783	Belongs to the Dps family
F9230_06960	COG1301	dicarboxylic acid transport
F9230_07095	COG3539	Fimbrial protein
F9230_07125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9230_07175	COG0625	glutathione transferase activity
F9230_07185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_07190	COG1473	amidohydrolase
F9230_07195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_07200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9230_07210	COG0765	amino acid transport
F9230_07215	COG1126	abc transporter atp-binding protein
F9230_07245	COG0463	Glycosyl transferase, family 2
F9230_07245	COG0457	Tetratricopeptide repeat
F9230_07250	COG1538	Outer membrane efflux protein
F9230_07265	COG0697	spore germination
F9230_07270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_07290	COG3712	iron ion homeostasis
F9230_07300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_07305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_07310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_07350	COG1131	(ABC) transporter
F9230_07355	COG0842	Transport permease protein
F9230_07360	COG0842	Transport permease protein
F9230_07385	COG1309	transcriptional regulator
F9230_07450	COG1733	regulation of RNA biosynthetic process
F9230_07455	COG0604	alcohol dehydrogenase
F9230_07465	COG1278	Cold shock
F9230_07475	COG3038	cytochrome b561
F9230_07495	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9230_07505	COG5377	YqaJ viral recombinase family
F9230_07745	COG3772	lysozyme
F9230_07795	COG2070	2-Nitropropane dioxygenase
F9230_07820	COG3634	alkyl hydroperoxide reductase activity
F9230_07840	COG0436	Aminotransferase
F9230_07845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F9230_07850	COG0386	Belongs to the glutathione peroxidase family
F9230_07875	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F9230_07890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9230_07915	COG0012	GTP binding
F9230_07920	COG2011	ABC-type metal ion transport system permease component
F9230_07925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9230_07930	COG1464	Belongs to the NlpA lipoprotein family
F9230_07935	COG1464	Belongs to the NlpA lipoprotein family
F9230_07965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F9230_07975	COG0204	Acyl-transferase
F9230_08020	COG0424	maF-like protein
F9230_08030	COG0126	phosphoglycerate kinase activity
F9230_08045	COG0697	spore germination
F9230_08075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_08080	COG3781	membrane
F9230_08110	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9230_08110	COG0506	proline dehydrogenase activity
F9230_08110	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9230_08120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9230_08135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9230_08165	COG0316	Belongs to the HesB IscA family
F9230_08170	COG0822	iron-sulfur transferase activity
F9230_08180	COG1959	2 iron, 2 sulfur cluster binding
F9230_08195	COG0776	regulation of translation
F9230_08200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_08225	COG0537	adenosine 5'-monophosphoramidase activity
F9230_08285	COG2175	clavaminate synthase activity
F9230_08290	COG3246	L-lysine catabolic process to acetate
F9230_08310	COG2855	membrane
F9230_08340	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_08350	COG0372	Belongs to the citrate synthase family
F9230_08380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9230_08385	COG0730	response to heat
F9230_08410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9230_08415	COG1944	ATP diphosphatase activity
F9230_08420	COG2207	Transcriptional regulator
F9230_08425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9230_08430	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9230_08460	COG2223	nitrite transmembrane transporter activity
F9230_08475	COG1346	cytolysis
F9230_08480	COG1380	Effector of murein hydrolase LrgA
F9230_08485	COG0583	DNA-binding transcription factor activity
F9230_08490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9230_08515	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F9230_08655	COG4383	Mu-like prophage protein gp29
F9230_08795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_08830	COG1846	Transcriptional regulator
F9230_08835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9230_08905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9230_08910	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F9230_08925	COG3300	MHYT domain
F9230_08925	COG5001	Diguanylate cyclase
F9230_08930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9230_08940	COG2814	Major facilitator Superfamily
F9230_08955	COG1132	(ABC) transporter
F9230_08965	COG0668	transmembrane transport
F9230_08970	COG3122	Protein conserved in bacteria
F9230_08990	COG0640	Transcriptional regulator
F9230_08995	COG0596	Alpha beta hydrolase
F9230_09000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_09005	COG1335	isochorismatase
F9230_09010	COG0251	oxidation-reduction process
F9230_09015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_09020	COG2233	PERMEase
F9230_09030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9230_09040	COG0183	Belongs to the thiolase family
F9230_09045	COG0583	DNA-binding transcription factor activity
F9230_09060	COG0439	Biotin carboxylase
F9230_09075	COG0511	ligase activity, forming carbon-carbon bonds
F9230_09085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_09090	COG0183	Belongs to the thiolase family
F9230_09095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_09100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9230_09105	COG3135	benzoate transporter
F9230_09110	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_09115	COG0633	Ferredoxin
F9230_09115	COG0543	2 iron, 2 sulfur cluster binding
F9230_09120	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9230_09125	COG4638	Rieske (2fe-2S)
F9230_09135	COG4829	muconolactone delta-isomerase
F9230_09140	COG4948	Mandelate Racemase Muconate Lactonizing
F9230_09145	COG0583	DNA-binding transcription factor activity
F9230_09150	COG2814	Major facilitator Superfamily
F9230_09245	COG0583	DNA-binding transcription factor activity
F9230_09260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9230_09265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9230_09270	COG0022	dehydrogenase e1 component
F9230_09275	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9230_09280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_09290	COG1063	alcohol dehydrogenase
F9230_09295	COG4628	conserved protein (DUF2132)
F9230_09315	COG1309	transcriptional regulator
F9230_09420	COG0596	Alpha beta hydrolase
F9230_09490	COG0864	Transcriptional regulator
F9230_09515	COG2814	Major facilitator Superfamily
F9230_09570	COG1960	acyl-CoA dehydrogenase activity
F9230_09575	COG1960	acyl-CoA dehydrogenase activity
F9230_09625	COG0552	protein localization to endoplasmic reticulum
F9230_09630	COG0612	Peptidase, M16
F9230_09660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9230_09660	COG0517	IMP dehydrogenase activity
F9230_09665	COG0133	tryptophan synthase activity
F9230_09675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9230_09690	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F9230_09695	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9230_09800	COG2850	peptidyl-arginine hydroxylation
F9230_09805	COG4585	Histidine kinase
F9230_09810	COG2197	response regulator
F9230_09815	COG0069	glutamate synthase activity
F9230_09835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F9230_09840	COG1454	alcohol dehydrogenase
F9230_09845	COG0824	Thioesterase
F9230_09850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9230_09875	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_09880	COG0183	Belongs to the thiolase family
F9230_09895	COG0583	DNA-binding transcription factor activity
F9230_09900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F9230_09910	COG3135	benzoate transporter
F9230_09915	COG1309	transcriptional regulator
F9230_09920	COG2076	Multidrug Resistance protein
F9230_09935	COG0589	response to stress
F9230_09945	COG0308	aminopeptidase N
F9230_09970	COG1253	flavin adenine dinucleotide binding
F9230_09990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9230_09995	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9230_10010	COG2431	L-lysine efflux transmembrane transporter activity
F9230_10025	COG0776	regulation of translation
F9230_10045	COG0590	tRNA wobble adenosine to inosine editing
F9230_10055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F9230_10090	COG0084	hydrolase, TatD family'
F9230_10110	COG1663	tetraacyldisaccharide 4'-kinase activity
F9230_10115	COG1132	(ABC) transporter
F9230_10125	COG0811	peptide transport
F9230_10130	COG1475	DNA binding
F9230_10135	COG1192	Involved in chromosome partitioning
F9230_10145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F9230_10150	COG3178	'Phosphotransferase
F9230_10160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_10165	COG1923	regulation of RNA biosynthetic process
F9230_10175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9230_10180	COG0802	atpase or kinase
F9230_10205	COG2707	UPF0756 membrane protein
F9230_10210	COG2814	Major facilitator Superfamily
F9230_10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9230_10220	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9230_10230	COG1454	alcohol dehydrogenase
F9230_10255	COG0531	amino acid
F9230_10260	COG4303	Ethanolamine ammonia lyase large subunit
F9230_10265	COG4302	ethanolamine ammonia-lyase activity
F9230_10275	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_10285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9230_10285	COG0519	Catalyzes the synthesis of GMP from XMP
F9230_10290	COG2353	YceI-like domain
F9230_10295	COG0456	acetyltransferase
F9230_10305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9230_10310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F9230_10365	COG0352	thiamine-phosphate diphosphorylase activity
F9230_10400	COG0612	Peptidase, M16
F9230_10410	COG1823	symporter activity
F9230_10415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9230_10450	COG2351	hydroxyisourate hydrolase activity
F9230_10460	COG1686	Belongs to the peptidase S11 family
F9230_10465	COG1252	NADH dehydrogenase
F9230_10470	COG1047	Peptidyl-prolyl cis-trans
F9230_10475	COG1254	Belongs to the acylphosphatase family
F9230_10480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9230_10480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9230_10505	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_10510	COG2819	hydrolase of the alpha beta superfamily
F9230_10525	COG0372	Belongs to the citrate synthase family
F9230_10555	COG0542	response to heat
F9230_10560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F9230_10575	COG3706	GGDEF domain
F9230_10585	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F9230_10590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9230_10600	COG0569	domain protein
F9230_10605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9230_10625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9230_10635	COG1585	Membrane protein implicated in regulation of membrane protease activity
F9230_10650	COG1294	oxidase, subunit
F9230_10655	COG4890	Cyd operon protein YbgT
F9230_10670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9230_10675	COG1309	transcriptional regulator
F9230_10680	COG1012	belongs to the aldehyde dehydrogenase family
F9230_10690	COG0579	oxidoreductase
F9230_10705	COG0772	Belongs to the SEDS family
F9230_10720	COG0148	phosphopyruvate hydratase activity
F9230_10740	COG0583	DNA-binding transcription factor activity
F9230_10745	COG0656	L-ascorbic acid biosynthetic process
F9230_10750	COG2814	Major facilitator Superfamily
F9230_10765	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9230_10765	COG1902	pentaerythritol trinitrate reductase activity
F9230_10775	COG2267	carboxylic ester hydrolase activity
F9230_10785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9230_10790	COG0702	epimerase
F9230_10830	COG1011	Hydrolase
F9230_10835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9230_10840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F9230_10845	COG2137	regulation of response to DNA damage stimulus
F9230_10860	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9230_10880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9230_10895	COG0575	Belongs to the CDS family
F9230_10900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9230_10920	COG3852	Histidine kinase
F9230_10935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_10940	COG0583	DNA-binding transcription factor activity
F9230_10945	COG0024	Methionine aminopeptidase
F9230_10970	COG1113	amino acid transport
F9230_10980	COG0786	glutamate:sodium symporter activity
F9230_10985	COG4773	Receptor
F9230_11030	COG0729	surface antigen
F9230_11055	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F9230_11070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9230_11075	COG1960	acyl-CoA dehydrogenase activity
F9230_11105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_11110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9230_11115	COG2890	protein-(glutamine-N5) methyltransferase activity
F9230_11120	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F9230_11135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_11165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9230_11170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9230_11175	COG1845	cytochrome c oxidase, subunit III
F9230_11180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9230_11200	COG0360	Binds together with S18 to 16S ribosomal RNA
F9230_11215	COG0305	Participates in initiation and elongation during chromosome replication
F9230_11220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F9230_11235	COG1305	Transglutaminase-like
F9230_11245	COG2308	Evidence 4 Homologs of previously reported genes of
F9230_11260	COG0445	tRNA wobble uridine modification
F9230_11290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9230_11295	COG0138	bifunctional purine biosynthesis protein purh
F9230_11300	COG0151	Belongs to the GarS family
F9230_11310	COG1024	Enoyl-CoA hydratase
F9230_11310	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9230_11320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9230_11325	COG2011	ABC-type metal ion transport system permease component
F9230_11365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9230_11375	COG4122	O-methyltransferase activity
F9230_11395	COG1137	ATPase activity
F9230_11400	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9230_11410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F9230_11415	COG0517	IMP dehydrogenase activity
F9230_11415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9230_11425	COG0406	alpha-ribazole phosphatase activity
F9230_11430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F9230_11465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9230_11475	COG0243	molybdopterin cofactor binding
F9230_11480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_11485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_11490	COG2223	nitrite transmembrane transporter activity
F9230_11500	COG1116	anion transmembrane transporter activity
F9230_11500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_11520	COG1643	Atp-dependent helicase
F9230_11530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9230_11570	COG2815	serine threonine protein kinase
F9230_11570	COG0515	serine threonine protein kinase
F9230_11585	COG1335	isochorismatase
F9230_11600	COG1610	YqeY-like protein
F9230_11605	COG4783	chaperone-mediated protein folding
F9230_11660	COG0778	Nitroreductase
F9230_11670	COG0513	Belongs to the DEAD box helicase family
F9230_11675	COG1278	Cold shock
F9230_11690	COG2363	Small membrane protein
F9230_11715	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9230_11720	COG0625	glutathione transferase activity
F9230_11725	COG0659	secondary active sulfate transmembrane transporter activity
F9230_11735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9230_11765	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_11770	COG1309	transcriptional regulator
F9230_11775	COG1960	acyl-CoA dehydrogenase activity
F9230_11780	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9230_11790	COG4770	biotin carboxylase activity
F9230_11805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9230_11810	COG2031	fatty acid transporter
F9230_11830	COG0540	Belongs to the ATCase OTCase family
F9230_11855	COG1765	OsmC-like protein
F9230_11865	COG0667	Aldo Keto reductase
F9230_11880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9230_11895	COG1522	sequence-specific DNA binding
F9230_11900	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9230_11915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9230_11925	COG0527	aspartate kinase activity
F9230_11935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F9230_11950	COG3038	cytochrome b561
F9230_11960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9230_11965	COG2252	PERMEase
F9230_11975	COG0415	Belongs to the DNA photolyase family
F9230_12005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F9230_12010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F9230_12020	COG0693	protein deglycase activity
F9230_12025	COG1960	acyl-CoA dehydrogenase activity
F9230_12030	COG1301	dicarboxylic acid transport
F9230_12035	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9230_12045	COG3139	Protein of unknown function (DUF1315)
F9230_12050	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9230_12055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9230_12065	COG0494	nUDIX hydrolase
F9230_12075	COG0642	Histidine kinase
F9230_12090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F9230_12100	COG1720	tRNA m6t6A37 methyltransferase activity
F9230_12170	COG0826	peptidase U32
F9230_12175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_12200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9230_12250	COG3706	GGDEF domain
F9230_12255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9230_12255	COG0475	glutathione-regulated potassium exporter activity
F9230_12260	COG0697	spore germination
F9230_12265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9230_12270	COG0235	Class ii aldolase
F9230_12310	COG4149	molybdate abc transporter
F9230_12315	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9230_12325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9230_12330	COG0243	molybdopterin cofactor binding
F9230_12335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9230_12340	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9230_12340	COG0315	cyclic pyranopterin monophosphate synthase activity
F9230_12345	COG0303	'Molybdopterin
F9230_12360	COG1131	(ABC) transporter
F9230_12365	COG0842	Transport permease protein
F9230_12380	COG2951	lytic endotransglycosylase activity
F9230_12415	COG0052	Belongs to the universal ribosomal protein uS2 family
F9230_12435	COG2175	clavaminate synthase activity
F9230_12450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_12455	COG0842	Transport permease protein
F9230_12490	COG1280	lysine exporter protein (LysE YggA)
F9230_12495	COG1522	sequence-specific DNA binding
F9230_12500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F9230_12510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F9230_12520	COG0019	diaminopimelate decarboxylase activity
F9230_12530	COG1113	amino acid transport
F9230_12535	COG1115	amino acid carrier protein
F9230_12550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9230_12555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9230_12560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9230_12565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9230_12605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9230_12610	COG3161	chorismate lyase activity
F9230_12620	COG0174	glutamine synthetase
F9230_12625	COG0512	Glutamine amidotransferase of anthranilate synthase
F9230_12630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F9230_12635	COG0134	indole-3-glycerol-phosphate synthase activity
F9230_12650	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_12655	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_12665	COG0302	gtp cyclohydrolase
F9230_12675	COG3706	GGDEF domain
F9230_12690	COG3739	integral membrane protein
F9230_12710	COG1741	Belongs to the pirin family
F9230_12725	COG1309	transcriptional regulator
F9230_12755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F9230_12760	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F9230_12770	COG0037	tRNA processing
F9230_12775	COG0741	lytic transglycosylase activity
F9230_12780	COG0501	Belongs to the peptidase M48B family
F9230_12795	COG2239	Acts as a magnesium transporter
F9230_12825	COG1253	flavin adenine dinucleotide binding
F9230_12830	COG2851	Citrate transporter
F9230_12870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9230_12875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9230_12900	COG0505	Belongs to the CarA family
F9230_12905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F9230_12915	COG0110	maltose O-acetyltransferase activity
F9230_12930	COG3695	enzyme binding
F9230_12945	COG2321	neutral zinc metallopeptidase
F9230_12950	COG2354	Protein conserved in bacteria
F9230_12965	COG2268	Band 7 protein
F9230_12975	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F9230_12985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9230_13000	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9230_13005	COG1053	succinate dehydrogenase
F9230_13010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F9230_13015	COG2009	succinate dehydrogenase
F9230_13025	COG2072	flavoprotein involved in K transport
F9230_13045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F9230_13045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9230_13070	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_13095	COG0564	pseudouridine synthase activity
F9230_13105	COG0358	DNA primase activity
F9230_13120	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F9230_13150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9230_13155	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F9230_13180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9230_13205	COG0586	Pfam SNARE associated Golgi protein
F9230_13220	COG1280	lysine exporter protein (LysE YggA)
F9230_13240	COG2921	Belongs to the UPF0250 family
F9230_13245	COG0321	lipoyl(octanoyl) transferase activity
F9230_13260	COG0531	amino acid
F9230_13280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9230_13285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9230_13285	COG1648	precorrin-2 dehydrogenase activity
F9230_13290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F9230_13300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F9230_13320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F9230_13340	COG0671	phosphoesterase, PA-phosphatase related
F9230_13345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9230_13355	COG1538	Outer membrane efflux protein
F9230_13360	COG0393	Putative heavy-metal-binding
F9230_13365	COG0393	Putative heavy-metal-binding
F9230_13375	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_13385	COG0525	valine-tRNA ligase activity
F9230_13395	COG0525	valine-tRNA ligase activity
F9230_13405	COG2852	Protein conserved in bacteria
F9230_13425	COG0583	DNA-binding transcription factor activity
F9230_13430	COG1278	Cold shock
F9230_13435	COG1278	Cold shock
F9230_13450	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_13455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9230_13460	COG0713	ATP synthesis coupled electron transport
F9230_13470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_13485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F9230_13505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9230_13515	COG2205	protein histidine kinase activity
F9230_13520	COG0745	RESPONSE REGULATOR receiver
F9230_13530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9230_13595	COG0439	Biotin carboxylase
F9230_13600	COG1802	Transcriptional regulator
F9230_13605	COG1652	LysM domain
F9230_13615	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_13630	COG1399	metal-binding, possibly nucleic acid-binding protein
F9230_13635	COG3101	peptidyl-lysine hydroxylation
F9230_13640	COG0009	L-threonylcarbamoyladenylate synthase
F9230_13650	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F9230_13655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F9230_13725	COG4106	trans-aconitate 2-methyltransferase activity
F9230_13740	COG2226	methyltransferase
F9230_13740	COG0596	Alpha beta hydrolase
F9230_13740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_13745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9230_13750	COG2193	ferroxidase activity
F9230_13770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9230_13775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F9230_13780	COG3115	cell septum assembly
F9230_13785	COG1196	nuclear chromosome segregation
F9230_13795	COG0730	response to heat
F9230_13805	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
F9230_13815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9230_13830	COG0488	(ABC) transporter
F9230_13855	COG3422	double-strand break repair
F9230_13865	COG2824	Alkylphosphonate utilization operon protein PhnA
F9230_13870	COG3189	MarR family transcriptional regulator
F9230_13890	COG0564	pseudouridine synthase activity
F9230_13895	COG0346	lactoylglutathione lyase activity
F9230_13940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F9230_13975	COG1902	pentaerythritol trinitrate reductase activity
F9230_13980	COG3659	wide pore channel activity
F9230_13990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9230_14000	COG1970	mechanosensitive ion channel activity
F9230_14005	COG1217	gtp-binding protein TYPA
F9230_14010	COG2233	PERMEase
F9230_14015	COG2813	Specifically methylates the guanine in position
F9230_14020	COG0833	amino acid
F9230_14035	COG0183	Belongs to the thiolase family
F9230_14055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9230_14070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9230_14075	COG2207	Transcriptional regulator
F9230_14080	COG0183	Belongs to the thiolase family
F9230_14085	COG1024	Enoyl-CoA hydratase
F9230_14085	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9230_14105	COG1272	protein, Hemolysin III
F9230_14110	COG0477	Major facilitator Superfamily
F9230_14120	COG1408	metallophosphoesterase
F9230_14125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9230_14135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9230_14160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F9230_14165	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9230_14170	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F9230_14175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F9230_14180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F9230_14190	COG0625	glutathione transferase activity
F9230_14195	COG2969	positive regulation of protein catabolic process
F9230_14250	COG2853	Lipoprotein
F9230_14255	COG2208	phosphoserine phosphatase activity
F9230_14265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9230_14270	COG1764	response to oxidative stress
F9230_14300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9230_14300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F9230_14315	COG0037	tRNA processing
F9230_14325	COG0248	Ppx GppA phosphatase
F9230_14350	COG0072	phenylalanine-tRNA ligase activity
F9230_14395	COG1238	metal cluster binding
F9230_14405	COG0625	glutathione transferase activity
F9230_14415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F9230_14425	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_14430	COG3028	Belongs to the UPF0307 family
F9230_14440	COG1660	Displays ATPase and GTPase activities
F9230_14445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F9230_14455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9230_14460	COG0617	tRNA 3'-terminal CCA addition
F9230_14465	COG1555	photosystem II stabilization
F9230_14470	COG3956	TIGRFAM MazG family protein
F9230_14480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9230_14495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9230_14500	COG5002	protein histidine kinase activity
F9230_14500	COG2205	protein histidine kinase activity
F9230_14500	COG0784	Response regulator, receiver
F9230_14505	COG1024	Enoyl-CoA hydratase
F9230_14510	COG2084	Dehydrogenase
F9230_14515	COG3622	Belongs to the hyi family
F9230_14530	COG0004	ammonium transporteR
F9230_14555	COG2814	Major facilitator Superfamily
F9230_14565	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_14575	COG3119	arylsulfatase activity
F9230_14670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9230_14680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9230_14690	COG0084	hydrolase, TatD family'
F9230_14705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9230_14720	COG0793	Belongs to the peptidase S41A family
F9230_14745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9230_14750	COG0280	phosphate acetyltransferase
F9230_14750	COG0857	belongs to the CobB CobQ family
F9230_14775	COG1917	Cupin 2, conserved barrel domain protein
F9230_14775	COG2207	Transcriptional regulator
F9230_14780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_14780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_14800	COG0740	serine-type endopeptidase activity
F9230_14810	COG4771	TonB-dependent receptor
F9230_14815	COG4774	siderophore transport
F9230_14830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9230_14840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9230_14840	COG2813	Specifically methylates the guanine in position
F9230_14945	COG0788	formyltetrahydrofolate deformylase activity
F9230_14970	COG4651	solute:proton antiporter activity
F9230_14970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9230_14995	COG0210	DNA helicase
F9230_15000	COG1929	Belongs to the glycerate kinase type-1 family
F9230_15040	COG2900	Belongs to the SlyX family
F9230_15045	COG0488	(ABC) transporter
F9230_15055	COG1560	Kdo2-lipid A biosynthetic process
F9230_15115	COG0473	3-isopropylmalate dehydrogenase activity
F9230_15130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F9230_15140	COG0583	DNA-binding transcription factor activity
F9230_15175	COG1280	lysine exporter protein (LysE YggA)
F9230_15190	COG1960	acyl-CoA dehydrogenase activity
F9230_15225	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F9230_15230	COG0583	DNA-binding transcription factor activity
F9230_15245	COG0564	pseudouridine synthase activity
F9230_15255	COG1530	ribonuclease E activity
F9230_15260	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_15285	COG1983	PspC domain protein
F9230_15305	COG0751	glycine-tRNA ligase activity
F9230_15330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F9230_15345	COG2226	methyltransferase
F9230_15360	COG0493	'glutamate synthase
F9230_15360	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9230_15370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9230_15380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9230_15385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F9230_15395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F9230_15405	COG0644	oxidoreductase
F9230_15405	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F9230_15430	COG0425	Belongs to the sulfur carrier protein TusA family
F9230_15435	COG4535	Mg2 and Co2 transporter CorC
F9230_15440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F9230_15445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9230_15465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9230_15475	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F9230_15495	COG2841	Protein conserved in bacteria
F9230_15500	COG0598	Magnesium transport protein CorA
F9230_15505	COG1185	polyribonucleotide nucleotidyltransferase activity
F9230_15515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F9230_15520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9230_15525	COG1074	ATP-dependent DNA helicase activity
F9230_15530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F9230_15560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9230_15575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9230_15585	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F9230_15590	COG2111	Na H antiporter
F9230_15590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9230_15595	COG1006	Multisubunit Na H antiporter MnhC subunit
F9230_15600	COG0651	ATP synthesis coupled electron transport
F9230_15605	COG1863	multisubunit Na H antiporter MnhE subunit
F9230_15610	COG2212	antiporter activity
F9230_15615	COG1320	monovalent cation:proton antiporter activity
F9230_15620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F9230_15630	COG0195	Participates in both transcription termination and antitermination
F9230_15690	COG0237	dephospho-CoA kinase activity
F9230_15700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9230_15710	COG0497	DNA recombination
F9230_15715	COG1678	Uncharacterized ACR, COG1678
F9230_15720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9230_15735	COG1289	transmembrane transporter activity
F9230_15750	COG1132	(ABC) transporter
F9230_15755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F9230_15825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F9230_15850	COG0326	Molecular chaperone. Has ATPase activity
F9230_15860	COG3047	cAMP biosynthetic process
F9230_15865	COG2056	Na+-H+ antiporter family
F9230_15890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F9230_15895	COG0085	RNA polymerase activity
F9230_15900	COG0222	ribosome binding
F9230_15905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F9230_15910	COG0081	regulation of translation
F9230_15915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F9230_15965	COG0546	phosphoglycolate phosphatase activity
F9230_15995	COG0824	Thioesterase
F9230_16015	COG0181	hydroxymethylbilane synthase activity
F9230_16025	COG3275	phosphorelay sensor kinase activity
F9230_16045	COG1538	Outer membrane efflux protein
F9230_16055	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F9230_16065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9230_16070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9230_16075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9230_16080	COG0772	Belongs to the SEDS family
F9230_16085	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F9230_16105	COG4974	Belongs to the 'phage' integrase family
F9230_16110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9230_16120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9230_16125	COG1686	Belongs to the peptidase S11 family
F9230_16130	COG2197	response regulator
F9230_16145	COG0793	Belongs to the peptidase S41A family
F9230_16150	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9230_16155	COG0795	lipopolysaccharide-transporting ATPase activity
F9230_16160	COG0795	lipopolysaccharide-transporting ATPase activity
F9230_16180	COG0586	Pfam SNARE associated Golgi protein
F9230_16195	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9230_16195	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9230_16205	COG0004	ammonium transporteR
F9230_16210	COG0347	Belongs to the P(II) protein family
F9230_16220	COG0606	chelatase, subunit chli
F9230_16240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9230_16255	COG0318	PFAM AMP-dependent synthetase and ligase
F9230_16265	COG0477	Major facilitator Superfamily
F9230_16270	COG2860	membrane
F9230_16275	COG3012	SEC-C Motif Domain Protein
F9230_16280	COG1253	flavin adenine dinucleotide binding
F9230_16300	COG2814	Major facilitator Superfamily
F9230_16310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9230_16390	COG0758	DNA mediated transformation
F9230_16400	COG0697	spore germination
F9230_16410	COG0386	Belongs to the glutathione peroxidase family
F9230_16450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F9230_16500	COG1121	(ABC) transporter
F9230_16505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9230_16510	COG1683	Conserved Protein
F9230_16520	COG2837	iron assimilation
F9230_16530	COG1876	peptidase activity
F9230_16540	COG0281	malic enzyme
F9230_16585	COG1715	Restriction endonuclease
F9230_16590	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9230_16590	COG0519	Catalyzes the synthesis of GMP from XMP
F9230_16600	COG2259	Doxx family
F9230_16605	COG0586	Pfam SNARE associated Golgi protein
F9230_16620	COG1192	Involved in chromosome partitioning
F9230_16630	COG0271	Belongs to the BolA IbaG family
F9230_16660	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_16700	COG2986	histidine ammonia-lyase
F9230_16715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F9230_16725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F9230_16745	COG0583	DNA-binding transcription factor activity
F9230_16750	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9230_16765	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F9230_16775	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9230_16780	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F9230_16790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9230_16795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9230_16800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F9230_16815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9230_16825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F9230_16835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9230_16875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F9230_16880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F9230_16885	COG1596	polysaccharide export
F9230_16910	COG0728	peptidoglycan biosynthetic process
F9230_16915	COG3023	N-Acetylmuramoyl-L-alanine amidase
F9230_16925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F9230_16935	COG3307	-O-antigen
F9230_16945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F9230_16950	COG0546	phosphoglycolate phosphatase activity
F9230_16955	COG1028	Short-chain dehydrogenase reductase Sdr
F9230_16975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F9230_16975	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F9230_16980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_16985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9230_16990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9230_16995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9230_17000	COG1116	anion transmembrane transporter activity
F9230_17005	COG1309	transcriptional regulator
F9230_17020	COG0196	riboflavin kinase activity
F9230_17025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F9230_17030	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F9230_17035	COG1047	Peptidyl-prolyl cis-trans
F9230_17050	COG2133	pyrroloquinoline quinone binding
F9230_17080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9230_17085	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9230_17090	COG2951	lytic endotransglycosylase activity
F9230_17095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9230_17110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9230_17130	COG0861	Integral membrane protein TerC family
F9230_17140	COG0754	glutathionylspermidine amidase activity
F9230_17150	COG0402	S-adenosylhomocysteine deaminase activity
F9230_17170	COG1230	cation diffusion facilitator family transporter
F9230_17185	COG0583	DNA-binding transcription factor activity
F9230_17200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9230_17205	COG0281	malic enzyme
F9230_17215	COG0706	membrane insertase activity
F9230_17220	COG0759	Could be involved in insertion of integral membrane proteins into the membrane