locus-tag	class	description
GBN68_00010	COG0592	DNA-directed DNA polymerase activity
GBN68_00020	COG0187	DNA topoisomerase II activity
GBN68_00030	COG0488	(ABC) transporter
GBN68_00090	COG0657	acetylesterase activity
GBN68_00100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBN68_00130	COG2133	pyrroloquinoline quinone binding
GBN68_00145	COG1047	Peptidyl-prolyl cis-trans
GBN68_00150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GBN68_00155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBN68_00160	COG0196	riboflavin kinase activity
GBN68_00175	COG1309	transcriptional regulator
GBN68_00180	COG1116	anion transmembrane transporter activity
GBN68_00185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GBN68_00190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBN68_00195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBN68_00200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBN68_00205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GBN68_00205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GBN68_00225	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_00230	COG0546	phosphoglycolate phosphatase activity
GBN68_00235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GBN68_00240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GBN68_00245	COG3307	-O-antigen
GBN68_00255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GBN68_00265	COG3023	N-Acetylmuramoyl-L-alanine amidase
GBN68_00270	COG0728	peptidoglycan biosynthetic process
GBN68_00295	COG1596	polysaccharide export
GBN68_00300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GBN68_00305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GBN68_00345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GBN68_00355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GBN68_00365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GBN68_00385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBN68_00390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GBN68_00400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GBN68_00405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GBN68_00415	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GBN68_00430	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GBN68_00435	COG0583	DNA-binding transcription factor activity
GBN68_00440	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBN68_00440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GBN68_00445	COG1105	Belongs to the carbohydrate kinase PfkB family
GBN68_00450	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GBN68_00450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBN68_00450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GBN68_00460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GBN68_00480	COG0271	Belongs to the BolA IbaG family
GBN68_00490	COG1192	Involved in chromosome partitioning
GBN68_00505	COG0586	Pfam SNARE associated Golgi protein
GBN68_00510	COG2259	Doxx family
GBN68_00520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GBN68_00520	COG0519	Catalyzes the synthesis of GMP from XMP
GBN68_00525	COG1715	Restriction endonuclease
GBN68_00570	COG0281	malic enzyme
GBN68_00580	COG1388	LysM domain
GBN68_00580	COG3409	Peptidoglycan-binding domain 1 protein
GBN68_00580	COG5632	N-Acetylmuramoyl-L-alanine amidase
GBN68_00590	COG2837	iron assimilation
GBN68_00600	COG1683	Conserved Protein
GBN68_00605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GBN68_00610	COG1121	(ABC) transporter
GBN68_00660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GBN68_00695	COG0386	Belongs to the glutathione peroxidase family
GBN68_00705	COG0697	spore germination
GBN68_00715	COG0758	DNA mediated transformation
GBN68_00795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBN68_00805	COG2814	Major facilitator Superfamily
GBN68_00825	COG1253	flavin adenine dinucleotide binding
GBN68_00830	COG3012	SEC-C Motif Domain Protein
GBN68_00835	COG2860	membrane
GBN68_00840	COG0477	Major facilitator Superfamily
GBN68_00850	COG0318	PFAM AMP-dependent synthetase and ligase
GBN68_00865	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GBN68_00885	COG0606	chelatase, subunit chli
GBN68_00895	COG0347	Belongs to the P(II) protein family
GBN68_00900	COG0004	ammonium transporteR
GBN68_00910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GBN68_00910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GBN68_00925	COG0586	Pfam SNARE associated Golgi protein
GBN68_00945	COG0795	lipopolysaccharide-transporting ATPase activity
GBN68_00950	COG0795	lipopolysaccharide-transporting ATPase activity
GBN68_00955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GBN68_00960	COG0793	Belongs to the peptidase S41A family
GBN68_00975	COG2197	response regulator
GBN68_00980	COG1686	Belongs to the peptidase S11 family
GBN68_00985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GBN68_00995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GBN68_01000	COG4974	Belongs to the 'phage' integrase family
GBN68_01020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GBN68_01025	COG0772	Belongs to the SEDS family
GBN68_01030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBN68_01035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GBN68_01040	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GBN68_01050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GBN68_01060	COG1538	Outer membrane efflux protein
GBN68_01080	COG3275	phosphorelay sensor kinase activity
GBN68_01090	COG0181	hydroxymethylbilane synthase activity
GBN68_01110	COG0824	Thioesterase
GBN68_01140	COG0546	phosphoglycolate phosphatase activity
GBN68_01190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBN68_01195	COG0081	regulation of translation
GBN68_01200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GBN68_01205	COG0222	ribosome binding
GBN68_01210	COG0085	RNA polymerase activity
GBN68_01215	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBN68_01240	COG2056	Na+-H+ antiporter family
GBN68_01245	COG3047	cAMP biosynthetic process
GBN68_01255	COG0326	Molecular chaperone. Has ATPase activity
GBN68_01280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GBN68_01350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBN68_01355	COG1132	(ABC) transporter
GBN68_01370	COG1289	transmembrane transporter activity
GBN68_01385	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBN68_01390	COG1678	Uncharacterized ACR, COG1678
GBN68_01395	COG0497	DNA recombination
GBN68_01405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBN68_01415	COG0237	dephospho-CoA kinase activity
GBN68_01475	COG0195	Participates in both transcription termination and antitermination
GBN68_01485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GBN68_01490	COG1320	monovalent cation:proton antiporter activity
GBN68_01495	COG2212	antiporter activity
GBN68_01500	COG1863	multisubunit Na H antiporter MnhE subunit
GBN68_01505	COG0651	ATP synthesis coupled electron transport
GBN68_01510	COG1006	Multisubunit Na H antiporter MnhC subunit
GBN68_01515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GBN68_01515	COG2111	Na H antiporter
GBN68_01520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBN68_01530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GBN68_01550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GBN68_01560	COG2226	methyltransferase
GBN68_01580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GBN68_01585	COG1074	ATP-dependent DNA helicase activity
GBN68_01590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GBN68_01595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GBN68_01605	COG1185	polyribonucleotide nucleotidyltransferase activity
GBN68_01610	COG0598	Magnesium transport protein CorA
GBN68_01615	COG2841	Protein conserved in bacteria
GBN68_01635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GBN68_01645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBN68_01670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBN68_01675	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GBN68_01680	COG4535	Mg2 and Co2 transporter CorC
GBN68_01685	COG0425	Belongs to the sulfur carrier protein TusA family
GBN68_01695	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GBN68_01695	COG0644	oxidoreductase
GBN68_01705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GBN68_01715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GBN68_01720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GBN68_01730	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GBN68_01740	COG0493	'glutamate synthase
GBN68_01740	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GBN68_01755	COG2226	methyltransferase
GBN68_01770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBN68_01795	COG0751	glycine-tRNA ligase activity
GBN68_01820	COG1983	PspC domain protein
GBN68_01845	COG0318	PFAM AMP-dependent synthetase and ligase
GBN68_01850	COG1530	ribonuclease E activity
GBN68_01860	COG0564	pseudouridine synthase activity
GBN68_01875	COG0583	DNA-binding transcription factor activity
GBN68_01890	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GBN68_01905	COG1960	acyl-CoA dehydrogenase activity
GBN68_01920	COG1280	lysine exporter protein (LysE YggA)
GBN68_01955	COG0583	DNA-binding transcription factor activity
GBN68_01965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBN68_01980	COG0473	3-isopropylmalate dehydrogenase activity
GBN68_02040	COG1560	Kdo2-lipid A biosynthetic process
GBN68_02050	COG0488	(ABC) transporter
GBN68_02055	COG2900	Belongs to the SlyX family
GBN68_02095	COG1929	Belongs to the glycerate kinase type-1 family
GBN68_02100	COG0210	DNA helicase
GBN68_02125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GBN68_02125	COG4651	solute:proton antiporter activity
GBN68_02150	COG0788	formyltetrahydrofolate deformylase activity
GBN68_02255	COG2813	Specifically methylates the guanine in position
GBN68_02255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBN68_02265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBN68_02280	COG4774	siderophore transport
GBN68_02285	COG4771	TonB-dependent receptor
GBN68_02295	COG0740	serine-type endopeptidase activity
GBN68_02315	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GBN68_02315	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GBN68_02325	COG1917	Cupin 2, conserved barrel domain protein
GBN68_02325	COG2207	Transcriptional regulator
GBN68_02350	COG0280	phosphate acetyltransferase
GBN68_02350	COG0857	belongs to the CobB CobQ family
GBN68_02355	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GBN68_02380	COG0793	Belongs to the peptidase S41A family
GBN68_02395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GBN68_02410	COG0084	hydrolase, TatD family'
GBN68_02420	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GBN68_02435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBN68_02445	COG2814	Major facilitator Superfamily
GBN68_02470	COG0004	ammonium transporteR
GBN68_02485	COG3622	Belongs to the hyi family
GBN68_02490	COG2084	Dehydrogenase
GBN68_02495	COG1024	Enoyl-CoA hydratase
GBN68_02500	COG2205	protein histidine kinase activity
GBN68_02500	COG5002	protein histidine kinase activity
GBN68_02500	COG0784	Response regulator, receiver
GBN68_02505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GBN68_02520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBN68_02530	COG3956	TIGRFAM MazG family protein
GBN68_02535	COG1555	photosystem II stabilization
GBN68_02540	COG0617	tRNA 3'-terminal CCA addition
GBN68_02545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GBN68_02555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GBN68_02560	COG1660	Displays ATPase and GTPase activities
GBN68_02570	COG3028	Belongs to the UPF0307 family
GBN68_02575	COG0318	PFAM AMP-dependent synthetase and ligase
GBN68_02595	COG0625	glutathione transferase activity
GBN68_02605	COG1238	metal cluster binding
GBN68_02650	COG0072	phenylalanine-tRNA ligase activity
GBN68_02675	COG0248	Ppx GppA phosphatase
GBN68_02685	COG0037	tRNA processing
GBN68_02700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBN68_02700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBN68_02730	COG1764	response to oxidative stress
GBN68_02735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GBN68_02745	COG2208	phosphoserine phosphatase activity
GBN68_02750	COG2853	Lipoprotein
GBN68_02805	COG2969	positive regulation of protein catabolic process
GBN68_02810	COG0625	glutathione transferase activity
GBN68_02820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GBN68_02825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBN68_02830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GBN68_02835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GBN68_02840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GBN68_02865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBN68_02875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBN68_02880	COG1408	metallophosphoesterase
GBN68_02890	COG0477	Major facilitator Superfamily
GBN68_02895	COG1272	protein, Hemolysin III
GBN68_02915	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBN68_02915	COG1024	Enoyl-CoA hydratase
GBN68_02920	COG0183	Belongs to the thiolase family
GBN68_02925	COG2207	Transcriptional regulator
GBN68_02930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GBN68_02965	COG0183	Belongs to the thiolase family
GBN68_02980	COG0833	amino acid
GBN68_02985	COG2813	Specifically methylates the guanine in position
GBN68_02990	COG2233	PERMEase
GBN68_02995	COG1217	gtp-binding protein TYPA
GBN68_03000	COG1970	mechanosensitive ion channel activity
GBN68_03010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GBN68_03020	COG3659	wide pore channel activity
GBN68_03025	COG1902	pentaerythritol trinitrate reductase activity
GBN68_03055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GBN68_03100	COG0346	lactoylglutathione lyase activity
GBN68_03110	COG0564	pseudouridine synthase activity
GBN68_03130	COG3189	MarR family transcriptional regulator
GBN68_03135	COG2824	Alkylphosphonate utilization operon protein PhnA
GBN68_03145	COG3422	double-strand break repair
GBN68_03165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBN68_03170	COG0488	(ABC) transporter
GBN68_03185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GBN68_03205	COG0730	response to heat
GBN68_03215	COG1196	nuclear chromosome segregation
GBN68_03220	COG3115	cell septum assembly
GBN68_03225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBN68_03230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GBN68_03250	COG2193	ferroxidase activity
GBN68_03255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GBN68_03260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBN68_03260	COG2226	methyltransferase
GBN68_03260	COG0596	Alpha beta hydrolase
GBN68_03275	COG4106	trans-aconitate 2-methyltransferase activity
GBN68_03345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GBN68_03350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GBN68_03360	COG0009	L-threonylcarbamoyladenylate synthase
GBN68_03365	COG3101	peptidyl-lysine hydroxylation
GBN68_03370	COG1399	metal-binding, possibly nucleic acid-binding protein
GBN68_03385	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_03395	COG1652	LysM domain
GBN68_03400	COG1802	Transcriptional regulator
GBN68_03405	COG0439	Biotin carboxylase
GBN68_03440	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBN68_03450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBN68_03450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GBN68_03455	COG0745	RESPONSE REGULATOR receiver
GBN68_03460	COG2205	protein histidine kinase activity
GBN68_03470	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBN68_03490	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GBN68_03505	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBN68_03515	COG0713	ATP synthesis coupled electron transport
GBN68_03520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GBN68_03525	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GBN68_03540	COG1278	Cold shock
GBN68_03545	COG1278	Cold shock
GBN68_03550	COG0583	DNA-binding transcription factor activity
GBN68_03570	COG2852	Protein conserved in bacteria
GBN68_03580	COG0525	valine-tRNA ligase activity
GBN68_03590	COG0525	valine-tRNA ligase activity
GBN68_03600	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_03610	COG0393	Putative heavy-metal-binding
GBN68_03615	COG0393	Putative heavy-metal-binding
GBN68_03620	COG1538	Outer membrane efflux protein
GBN68_03630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBN68_03635	COG0671	phosphoesterase, PA-phosphatase related
GBN68_03655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GBN68_03665	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GBN68_03675	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBN68_03680	COG1648	precorrin-2 dehydrogenase activity
GBN68_03680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GBN68_03685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GBN68_03705	COG0531	amino acid
GBN68_03720	COG0321	lipoyl(octanoyl) transferase activity
GBN68_03725	COG2921	Belongs to the UPF0250 family
GBN68_03745	COG1280	lysine exporter protein (LysE YggA)
GBN68_03760	COG0586	Pfam SNARE associated Golgi protein
GBN68_03785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBN68_03810	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GBN68_03815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBN68_03845	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GBN68_03860	COG0358	DNA primase activity
GBN68_03870	COG0564	pseudouridine synthase activity
GBN68_03895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GBN68_03920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GBN68_03920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GBN68_03935	COG0300	oxidoreductase activity
GBN68_03940	COG2072	flavoprotein involved in K transport
GBN68_03950	COG2009	succinate dehydrogenase
GBN68_03955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GBN68_03960	COG1053	succinate dehydrogenase
GBN68_03965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GBN68_03980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBN68_03990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GBN68_04000	COG2268	Band 7 protein
GBN68_04015	COG2354	Protein conserved in bacteria
GBN68_04020	COG2321	neutral zinc metallopeptidase
GBN68_04035	COG3695	enzyme binding
GBN68_04055	COG0110	maltose O-acetyltransferase activity
GBN68_04065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GBN68_04070	COG0505	Belongs to the CarA family
GBN68_04095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBN68_04100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GBN68_04140	COG2851	Citrate transporter
GBN68_04145	COG1253	flavin adenine dinucleotide binding
GBN68_04175	COG2239	Acts as a magnesium transporter
GBN68_04190	COG0501	Belongs to the peptidase M48B family
GBN68_04195	COG0741	lytic transglycosylase activity
GBN68_04200	COG0037	tRNA processing
GBN68_04210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GBN68_04215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GBN68_04245	COG1309	transcriptional regulator
GBN68_04260	COG1741	Belongs to the pirin family
GBN68_04280	COG3739	integral membrane protein
GBN68_04295	COG3706	GGDEF domain
GBN68_04305	COG0302	gtp cyclohydrolase
GBN68_04320	COG0134	indole-3-glycerol-phosphate synthase activity
GBN68_04325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GBN68_04330	COG0512	Glutamine amidotransferase of anthranilate synthase
GBN68_04335	COG0174	glutamine synthetase
GBN68_04345	COG3161	chorismate lyase activity
GBN68_04350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GBN68_04390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GBN68_04395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GBN68_04400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBN68_04405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBN68_04420	COG1115	amino acid carrier protein
GBN68_04425	COG1113	amino acid transport
GBN68_04435	COG0019	diaminopimelate decarboxylase activity
GBN68_04445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GBN68_04470	COG1522	sequence-specific DNA binding
GBN68_04475	COG1280	lysine exporter protein (LysE YggA)
GBN68_04510	COG0842	Transport permease protein
GBN68_04515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBN68_04530	COG2175	clavaminate synthase activity
GBN68_04550	COG0052	Belongs to the universal ribosomal protein uS2 family
GBN68_04585	COG2951	lytic endotransglycosylase activity
GBN68_04600	COG0842	Transport permease protein
GBN68_04605	COG1131	(ABC) transporter
GBN68_04615	COG0303	'Molybdopterin
GBN68_04620	COG0521	Mo-molybdopterin cofactor biosynthetic process
GBN68_04620	COG0315	cyclic pyranopterin monophosphate synthase activity
GBN68_04625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GBN68_04630	COG0243	molybdopterin cofactor binding
GBN68_04635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GBN68_04645	COG0725	ABC transporter, periplasmic molybdate-binding protein
GBN68_04650	COG4149	molybdate abc transporter
GBN68_04665	COG0277	FAD linked oxidase domain protein
GBN68_04690	COG0235	Class ii aldolase
GBN68_04695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBN68_04700	COG0697	spore germination
GBN68_04705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GBN68_04705	COG0475	glutathione-regulated potassium exporter activity
GBN68_04765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GBN68_04785	COG3634	alkyl hydroperoxide reductase activity
GBN68_04790	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GBN68_04795	COG0826	peptidase U32
GBN68_04850	COG1720	tRNA m6t6A37 methyltransferase activity
GBN68_04860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GBN68_04875	COG0642	Histidine kinase
GBN68_04885	COG0494	nUDIX hydrolase
GBN68_04895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GBN68_04900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBN68_04905	COG3139	Protein of unknown function (DUF1315)
GBN68_04920	COG1301	dicarboxylic acid transport
GBN68_04925	COG1960	acyl-CoA dehydrogenase activity
GBN68_04930	COG0693	protein deglycase activity
GBN68_04940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBN68_04945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GBN68_04975	COG0415	Belongs to the DNA photolyase family
GBN68_04985	COG2252	PERMEase
GBN68_04990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBN68_05000	COG3038	cytochrome b561
GBN68_05015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBN68_05025	COG0527	aspartate kinase activity
GBN68_05035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GBN68_05050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GBN68_05055	COG1522	sequence-specific DNA binding
GBN68_05070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBN68_05085	COG0667	Aldo Keto reductase
GBN68_05095	COG1765	OsmC-like protein
GBN68_05120	COG0540	Belongs to the ATCase OTCase family
GBN68_05140	COG2031	fatty acid transporter
GBN68_05145	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GBN68_05160	COG4770	biotin carboxylase activity
GBN68_05170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GBN68_05175	COG1960	acyl-CoA dehydrogenase activity
GBN68_05180	COG1309	transcriptional regulator
GBN68_05185	COG0318	PFAM AMP-dependent synthetase and ligase
GBN68_05215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GBN68_05225	COG0659	secondary active sulfate transmembrane transporter activity
GBN68_05230	COG0625	glutathione transferase activity
GBN68_05235	COG2249	NAD(P)H dehydrogenase (quinone) activity
GBN68_05260	COG2363	Small membrane protein
GBN68_05275	COG1278	Cold shock
GBN68_05280	COG0513	Belongs to the DEAD box helicase family
GBN68_05290	COG0778	Nitroreductase
GBN68_05315	COG0167	dihydroorotate dehydrogenase activity
GBN68_05345	COG4783	chaperone-mediated protein folding
GBN68_05350	COG1610	YqeY-like protein
GBN68_05380	COG0515	serine threonine protein kinase
GBN68_05380	COG2815	serine threonine protein kinase
GBN68_05420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GBN68_05430	COG1643	Atp-dependent helicase
GBN68_05450	COG1116	anion transmembrane transporter activity
GBN68_05450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBN68_05460	COG2223	nitrite transmembrane transporter activity
GBN68_05465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBN68_05470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBN68_05475	COG0243	molybdopterin cofactor binding
GBN68_05485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GBN68_05520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GBN68_05525	COG0406	alpha-ribazole phosphatase activity
GBN68_05535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GBN68_05535	COG0517	IMP dehydrogenase activity
GBN68_05540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GBN68_05550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GBN68_05555	COG1137	ATPase activity
GBN68_05575	COG4122	O-methyltransferase activity
GBN68_05585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GBN68_05630	COG2011	ABC-type metal ion transport system permease component
GBN68_05635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBN68_05645	COG1250	3-hydroxyacyl-CoA dehydrogenase
GBN68_05645	COG1024	Enoyl-CoA hydratase
GBN68_05655	COG0151	Belongs to the GarS family
GBN68_05660	COG0138	bifunctional purine biosynthesis protein purh
GBN68_05665	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GBN68_05695	COG0445	tRNA wobble uridine modification
GBN68_05710	COG2308	Evidence 4 Homologs of previously reported genes of
GBN68_05720	COG1305	Transglutaminase-like
GBN68_05735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBN68_05740	COG0305	Participates in initiation and elongation during chromosome replication
GBN68_05755	COG0360	Binds together with S18 to 16S ribosomal RNA
GBN68_05775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GBN68_05780	COG1845	cytochrome c oxidase, subunit III
GBN68_05785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GBN68_05790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GBN68_05820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBN68_05835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GBN68_05840	COG2890	protein-(glutamine-N5) methyltransferase activity
GBN68_05845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GBN68_05850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GBN68_05880	COG1960	acyl-CoA dehydrogenase activity
GBN68_05885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBN68_05900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GBN68_05925	COG0729	surface antigen
GBN68_05970	COG4773	Receptor
GBN68_05975	COG0786	glutamate:sodium symporter activity
GBN68_05985	COG1113	amino acid transport
GBN68_06010	COG0024	Methionine aminopeptidase
GBN68_06015	COG0583	DNA-binding transcription factor activity
GBN68_06020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBN68_06035	COG3852	Histidine kinase
GBN68_06055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBN68_06060	COG0575	Belongs to the CDS family
GBN68_06075	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBN68_06095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GBN68_06110	COG3293	Transposase
GBN68_06115	COG2137	regulation of response to DNA damage stimulus
GBN68_06120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBN68_06125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GBN68_06130	COG1011	Hydrolase
GBN68_06175	COG0702	epimerase
GBN68_06180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GBN68_06200	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBN68_06200	COG1902	pentaerythritol trinitrate reductase activity
GBN68_06215	COG2814	Major facilitator Superfamily
GBN68_06225	COG0583	DNA-binding transcription factor activity
GBN68_06245	COG0148	phosphopyruvate hydratase activity
GBN68_06260	COG0772	Belongs to the SEDS family
GBN68_06270	COG2814	Major facilitator Superfamily
GBN68_06275	COG0579	oxidoreductase
GBN68_06285	COG1012	belongs to the aldehyde dehydrogenase family
GBN68_06290	COG1309	transcriptional regulator
GBN68_06295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GBN68_06310	COG4890	Cyd operon protein YbgT
GBN68_06315	COG1294	oxidase, subunit
GBN68_06330	COG1585	Membrane protein implicated in regulation of membrane protease activity
GBN68_06340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GBN68_06360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GBN68_06365	COG0569	domain protein
GBN68_06375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBN68_06380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GBN68_06390	COG3706	GGDEF domain
GBN68_06405	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GBN68_06410	COG0542	response to heat
GBN68_06440	COG0372	Belongs to the citrate synthase family
GBN68_06465	COG0318	PFAM AMP-dependent synthetase and ligase
GBN68_06490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GBN68_06490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GBN68_06495	COG1254	Belongs to the acylphosphatase family
GBN68_06500	COG1047	Peptidyl-prolyl cis-trans
GBN68_06505	COG1252	NADH dehydrogenase
GBN68_06510	COG1686	Belongs to the peptidase S11 family
GBN68_06520	COG2351	hydroxyisourate hydrolase activity
GBN68_06640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBN68_06655	COG2351	hydroxyisourate hydrolase activity
GBN68_06670	COG5002	protein histidine kinase activity
GBN68_06680	COG4372	Transposase
GBN68_06715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GBN68_06730	COG2323	membrane
GBN68_06770	COG2223	nitrite transmembrane transporter activity
GBN68_06775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GBN68_06780	COG1877	trehalose-phosphatase activity
GBN68_06795	COG1570	exodeoxyribonuclease VII activity
GBN68_06830	COG2433	Pfam Transposase IS66
GBN68_06850	COG0582	viral genome integration into host DNA
GBN68_06870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBN68_06875	COG1823	symporter activity
GBN68_06885	COG0612	Peptidase, M16
GBN68_06920	COG0352	thiamine-phosphate diphosphorylase activity
GBN68_06965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBN68_06970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBN68_06990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GBN68_06990	COG0519	Catalyzes the synthesis of GMP from XMP
GBN68_07000	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_07010	COG4302	ethanolamine ammonia-lyase activity
GBN68_07015	COG4303	Ethanolamine ammonia lyase large subunit
GBN68_07020	COG0531	amino acid
GBN68_07040	COG1454	alcohol dehydrogenase
GBN68_07050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GBN68_07055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GBN68_07060	COG2814	Major facilitator Superfamily
GBN68_07065	COG2707	UPF0756 membrane protein
GBN68_07070	COG1187	pseudouridine synthase activity
GBN68_07085	COG0564	pseudouridine synthase activity
GBN68_07090	COG0802	atpase or kinase
GBN68_07095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GBN68_07105	COG1923	regulation of RNA biosynthetic process
GBN68_07110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GBN68_07120	COG3178	'Phosphotransferase
GBN68_07125	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GBN68_07135	COG1192	Involved in chromosome partitioning
GBN68_07140	COG1475	DNA binding
GBN68_07145	COG0811	peptide transport
GBN68_07155	COG1132	(ABC) transporter
GBN68_07160	COG1663	tetraacyldisaccharide 4'-kinase activity
GBN68_07180	COG0084	hydrolase, TatD family'
GBN68_07215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBN68_07225	COG0590	tRNA wobble adenosine to inosine editing
GBN68_07245	COG0776	regulation of translation
GBN68_07260	COG2431	L-lysine efflux transmembrane transporter activity
GBN68_07275	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GBN68_07280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GBN68_07300	COG1253	flavin adenine dinucleotide binding
GBN68_07325	COG0308	aminopeptidase N
GBN68_07335	COG0589	response to stress
GBN68_07350	COG2076	Multidrug Resistance protein
GBN68_07355	COG1309	transcriptional regulator
GBN68_07360	COG3135	benzoate transporter
GBN68_07370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GBN68_07375	COG0583	DNA-binding transcription factor activity
GBN68_07390	COG0183	Belongs to the thiolase family
GBN68_07395	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_07415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBN68_07420	COG0824	Thioesterase
GBN68_07425	COG1454	alcohol dehydrogenase
GBN68_07430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBN68_07450	COG0069	glutamate synthase activity
GBN68_07455	COG2197	response regulator
GBN68_07465	COG2850	peptidyl-arginine hydroxylation
GBN68_07475	COG0424	maF-like protein
GBN68_07485	COG0126	phosphoglycerate kinase activity
GBN68_07500	COG0697	spore germination
GBN68_07525	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GBN68_07535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBN68_07540	COG3781	membrane
GBN68_07575	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GBN68_07575	COG0506	proline dehydrogenase activity
GBN68_07575	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GBN68_07585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBN68_07600	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GBN68_07630	COG0316	Belongs to the HesB IscA family
GBN68_07635	COG0822	iron-sulfur transferase activity
GBN68_07645	COG1959	2 iron, 2 sulfur cluster binding
GBN68_07660	COG0776	regulation of translation
GBN68_07665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GBN68_07695	COG0537	adenosine 5'-monophosphoramidase activity
GBN68_07730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GBN68_07735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GBN68_07750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBN68_07760	COG0133	tryptophan synthase activity
GBN68_07765	COG0517	IMP dehydrogenase activity
GBN68_07765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GBN68_07795	COG0612	Peptidase, M16
GBN68_07800	COG0552	protein localization to endoplasmic reticulum
GBN68_07850	COG1960	acyl-CoA dehydrogenase activity
GBN68_07855	COG1960	acyl-CoA dehydrogenase activity
GBN68_07910	COG2814	Major facilitator Superfamily
GBN68_07935	COG0864	Transcriptional regulator
GBN68_08005	COG0596	Alpha beta hydrolase
GBN68_08095	COG4628	conserved protein (DUF2132)
GBN68_08100	COG1063	alcohol dehydrogenase
GBN68_08110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBN68_08115	COG0508	dehydrogenase complex catalyzes the overall conversion of
GBN68_08120	COG0022	dehydrogenase e1 component
GBN68_08125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GBN68_08130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GBN68_08215	COG2814	Major facilitator Superfamily
GBN68_08220	COG0583	DNA-binding transcription factor activity
GBN68_08225	COG4948	Mandelate Racemase Muconate Lactonizing
GBN68_08230	COG4829	muconolactone delta-isomerase
GBN68_08240	COG4638	Rieske (2fe-2S)
GBN68_08245	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GBN68_08250	COG0543	2 iron, 2 sulfur cluster binding
GBN68_08250	COG0633	Ferredoxin
GBN68_08255	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_08260	COG3135	benzoate transporter
GBN68_08265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GBN68_08270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GBN68_08275	COG0183	Belongs to the thiolase family
GBN68_08280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBN68_08290	COG0511	ligase activity, forming carbon-carbon bonds
GBN68_08305	COG0439	Biotin carboxylase
GBN68_08320	COG0583	DNA-binding transcription factor activity
GBN68_08325	COG0183	Belongs to the thiolase family
GBN68_08335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GBN68_08345	COG2233	PERMEase
GBN68_08350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBN68_08355	COG0251	oxidation-reduction process
GBN68_08360	COG1335	isochorismatase
GBN68_08365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBN68_08370	COG0596	Alpha beta hydrolase
GBN68_08375	COG0640	Transcriptional regulator
GBN68_08395	COG3122	Protein conserved in bacteria
GBN68_08400	COG0668	transmembrane transport
GBN68_08410	COG1132	(ABC) transporter
GBN68_08425	COG2814	Major facilitator Superfamily
GBN68_08435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBN68_08440	COG3300	MHYT domain
GBN68_08440	COG5001	Diguanylate cyclase
GBN68_08455	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GBN68_08460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBN68_08530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GBN68_08550	COG3179	chitinase
GBN68_08650	COG4695	Portal protein
GBN68_08710	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GBN68_08850	COG0582	viral genome integration into host DNA
GBN68_08855	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GBN68_08880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GBN68_08885	COG0583	DNA-binding transcription factor activity
GBN68_08890	COG1380	Effector of murein hydrolase LrgA
GBN68_08895	COG1346	cytolysis
GBN68_08910	COG2223	nitrite transmembrane transporter activity
GBN68_08940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBN68_08945	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GBN68_08950	COG2207	Transcriptional regulator
GBN68_08955	COG1944	ATP diphosphatase activity
GBN68_08960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GBN68_08985	COG0730	response to heat
GBN68_08990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBN68_09035	COG0204	Acyl-transferase
GBN68_09075	COG1464	Belongs to the NlpA lipoprotein family
GBN68_09080	COG1464	Belongs to the NlpA lipoprotein family
GBN68_09085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBN68_09090	COG2011	ABC-type metal ion transport system permease component
GBN68_09100	COG0012	GTP binding
GBN68_09125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GBN68_09140	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GBN68_09165	COG0386	Belongs to the glutathione peroxidase family
GBN68_09170	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBN68_09175	COG0436	Aminotransferase
GBN68_09195	COG3634	alkyl hydroperoxide reductase activity
GBN68_09220	COG2070	2-Nitropropane dioxygenase
GBN68_09230	COG3038	cytochrome b561
GBN68_09260	COG1278	Cold shock
GBN68_09270	COG0604	alcohol dehydrogenase
GBN68_09275	COG1733	regulation of RNA biosynthetic process
GBN68_09320	COG3293	Transposase
GBN68_09355	COG1309	transcriptional regulator
GBN68_09380	COG0842	Transport permease protein
GBN68_09385	COG0842	Transport permease protein
GBN68_09390	COG1131	(ABC) transporter
GBN68_09445	COG1538	Outer membrane efflux protein
GBN68_09450	COG0463	Glycosyl transferase, family 2
GBN68_09450	COG0457	Tetratricopeptide repeat
GBN68_09535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GBN68_09580	COG0714	Associated with various cellular activities
GBN68_09590	COG2879	small protein
GBN68_09595	COG1966	Carbon starvation protein
GBN68_09600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBN68_09620	COG0254	rRNA binding
GBN68_09640	COG1067	ATP-dependent peptidase activity
GBN68_09645	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GBN68_09650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GBN68_09655	COG0616	signal peptide processing
GBN68_09660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GBN68_09670	COG0573	inorganic phosphate transmembrane transporter activity
GBN68_09675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GBN68_09680	COG0076	glutamate decarboxylase activity
GBN68_09685	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GBN68_09700	COG0671	phosphoesterase, PA-phosphatase related
GBN68_09705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBN68_09715	COG1733	regulation of RNA biosynthetic process
GBN68_09720	COG0702	epimerase
GBN68_09750	COG0556	nucleotide-excision repair
GBN68_09785	COG0436	Aminotransferase
GBN68_09820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GBN68_09825	COG1381	Involved in DNA repair and RecF pathway recombination
GBN68_09835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GBN68_09850	COG0681	Belongs to the peptidase S26 family
GBN68_09885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBN68_09895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBN68_10055	COG1570	exodeoxyribonuclease VII activity
GBN68_10185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GBN68_10205	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBN68_10215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GBN68_10230	COG4208	sulfate ABC transporter
GBN68_10235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GBN68_10240	COG0583	DNA-binding transcription factor activity
GBN68_10260	COG0602	queuosine metabolic process
GBN68_10265	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GBN68_10280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GBN68_10290	COG0583	DNA-binding transcription factor activity
GBN68_10295	COG2353	YceI-like domain
GBN68_10300	COG1051	belongs to the nudix hydrolase family
GBN68_10300	COG1056	cytidyltransferase-related domain
GBN68_10305	COG1024	Enoyl-CoA hydratase
GBN68_10310	COG0778	Nitroreductase
GBN68_10320	COG3323	Protein of unknown function (DUF1653)
GBN68_10320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBN68_10330	COG0047	phosphoribosylformylglycinamidine synthase activity
GBN68_10330	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBN68_10350	COG2255	four-way junction helicase activity
GBN68_10365	COG0824	Thioesterase
GBN68_10385	COG0823	Involved in the tonB-independent uptake of proteins
GBN68_10405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBN68_10440	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GBN68_10445	COG0628	permease
GBN68_10450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GBN68_10455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GBN68_10475	COG0658	competence protein
GBN68_10475	COG2333	competence protein COMEC
GBN68_10480	COG1136	(ABC) transporter
GBN68_10485	COG4591	ABC-type transport system involved in lipoprotein release permease component
GBN68_10500	COG1671	Belongs to the UPF0178 family
GBN68_10510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBN68_10515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GBN68_10560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GBN68_10565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GBN68_10570	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GBN68_10575	COG5001	Diguanylate cyclase
GBN68_10575	COG1716	ATPase activity
GBN68_10580	COG0280	phosphate acetyltransferase
GBN68_10580	COG0281	malic enzyme
GBN68_10590	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GBN68_10610	COG0446	pyridine nucleotide-disulphide oxidoreductase
GBN68_10610	COG1902	pentaerythritol trinitrate reductase activity
GBN68_10615	COG0277	FAD linked oxidase domain protein
GBN68_10625	COG2186	Transcriptional regulator
GBN68_10640	COG5001	Diguanylate cyclase
GBN68_10640	COG4251	negative regulation of phosphorylation
GBN68_10640	COG3706	GGDEF domain
GBN68_10640	COG2203	Gaf domain
GBN68_10645	COG0418	dihydroorotase activity
GBN68_10650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GBN68_10660	COG0833	amino acid
GBN68_10670	COG0833	amino acid
GBN68_10695	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GBN68_10710	COG4172	Belongs to the ABC transporter superfamily
GBN68_10715	COG4239	(ABC) transporter, permease
GBN68_10720	COG4174	ABC transporter (Permease)
GBN68_10725	COG4166	transmembrane transport
GBN68_10730	COG1388	LysM domain
GBN68_10730	COG0741	lytic transglycosylase activity
GBN68_10735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GBN68_10750	COG0657	acetylesterase activity
GBN68_10770	COG0583	DNA-binding transcription factor activity
GBN68_10775	COG1388	LysM domain
GBN68_10775	COG4942	peptidase
GBN68_10790	COG0753	catalase activity
GBN68_10805	COG0789	Transcriptional regulator
GBN68_10820	COG1686	Belongs to the peptidase S11 family
GBN68_10825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GBN68_10845	COG2915	High frequency lysogenization protein hflD homolog
GBN68_10865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GBN68_10870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GBN68_10890	COG0006	proline dipeptidase activity
GBN68_10960	COG1785	Belongs to the alkaline phosphatase family
GBN68_10965	COG1785	Belongs to the alkaline phosphatase family
GBN68_10985	COG4770	biotin carboxylase activity
GBN68_11010	COG0583	DNA-binding transcription factor activity
GBN68_11015	COG2217	Heavy metal translocating P-type atpase
GBN68_11025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBN68_11040	COG2234	aminopeptidase activity
GBN68_11050	COG3384	dioxygenase
GBN68_11060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GBN68_11065	COG2878	Part of a membrane complex involved in electron transport
GBN68_11070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GBN68_11095	COG0768	penicillin binding
GBN68_11100	COG0742	ribosomal rna small subunit methyltransferase
GBN68_11150	COG1597	lipid kinase activity
GBN68_11165	COG0477	Major facilitator Superfamily
GBN68_11175	COG2264	protein methyltransferase activity
GBN68_11180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBN68_11205	COG0604	alcohol dehydrogenase
GBN68_11205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBN68_11205	COG3321	synthase
GBN68_11205	COG4221	oxidoreductase activity
GBN68_11220	COG1695	Transcriptional regulator
GBN68_11265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBN68_11270	COG1773	rubredoxin
GBN68_11275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GBN68_11285	COG0583	DNA-binding transcription factor activity
GBN68_11305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GBN68_11310	COG4181	ATPase activity
GBN68_11335	COG4771	TonB-dependent receptor
GBN68_11355	COG0306	phosphate transporter
GBN68_11370	COG2852	Protein conserved in bacteria
GBN68_11385	COG2223	nitrite transmembrane transporter activity
GBN68_11390	COG2207	Transcriptional regulator
GBN68_11395	COG0242	peptide deformylase activity
GBN68_11400	COG0477	Major facilitator Superfamily
GBN68_11445	COG2199	diguanylate cyclase activity
GBN68_11445	COG2203	Gaf domain
GBN68_11455	COG4681	YaeQ
GBN68_11460	COG0523	cobalamin synthesis protein
GBN68_11470	COG1607	acyl-coa hydrolase
GBN68_11475	COG1752	Esterase of the alpha-beta hydrolase superfamily
GBN68_11485	COG1115	amino acid carrier protein
GBN68_11490	COG0786	glutamate:sodium symporter activity
GBN68_11505	COG2814	Major facilitator Superfamily
GBN68_11510	COG1289	transmembrane transporter activity
GBN68_11520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GBN68_11590	COG2832	Protein of unknown function (DUF454)
GBN68_11600	COG5510	response to toxic substance
GBN68_11605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GBN68_11615	COG0784	Response regulator, receiver
GBN68_11615	COG2198	Histidine kinase
GBN68_11615	COG0643	Histidine kinase
GBN68_11620	COG0840	transmembrane signaling receptor activity
GBN68_11645	COG1566	PFAM secretion protein HlyD family protein
GBN68_11690	COG2358	TRAP transporter, solute receptor (TAXI family
GBN68_11705	COG0489	protein tyrosine kinase activity
GBN68_11730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBN68_11730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBN68_11770	COG4716	Myosin-crossreactive antigen
GBN68_11800	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GBN68_11805	COG2081	HI0933 family
GBN68_11815	COG0668	transmembrane transport
GBN68_11835	COG0765	amino acid transport
GBN68_11840	COG0765	amino acid transport
GBN68_11845	COG1126	abc transporter atp-binding protein
GBN68_11855	COG0004	ammonium transporteR
GBN68_11870	COG0642	Histidine kinase
GBN68_11875	COG0745	RESPONSE REGULATOR receiver
GBN68_11900	COG1752	Esterase of the alpha-beta hydrolase superfamily
GBN68_11915	COG0142	geranyltranstransferase activity
GBN68_11920	COG2828	Protein conserved in bacteria
GBN68_11925	COG1113	amino acid transport
GBN68_11940	COG1113	amino acid transport
GBN68_11960	COG0625	glutathione transferase activity
GBN68_11970	COG2072	flavoprotein involved in K transport
GBN68_11975	COG0431	NADPH-dependent FMN reductase
GBN68_11980	COG0798	PFAM Bile acid sodium symporter
GBN68_11990	COG0640	Transcriptional regulator
GBN68_12045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GBN68_12055	COG0424	maF-like protein
GBN68_12060	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GBN68_12065	COG1792	Involved in formation and maintenance of cell shape
GBN68_12070	COG1077	Cell shape determining protein MreB Mrl
GBN68_12075	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBN68_12085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBN68_12130	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GBN68_12140	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_12145	COG2610	gluconate transmembrane transporter activity
GBN68_12150	COG0583	DNA-binding transcription factor activity
GBN68_12160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GBN68_12170	COG4772	TonB-dependent receptor
GBN68_12175	COG4993	Dehydrogenase
GBN68_12180	COG3659	wide pore channel activity
GBN68_12185	COG3420	alginic acid biosynthetic process
GBN68_12190	COG0710	3-dehydroquinate dehydratase activity
GBN68_12195	COG3485	protocatechuate 3,4-dioxygenase
GBN68_12200	COG3485	protocatechuate 3,4-dioxygenase
GBN68_12205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBN68_12210	COG2271	Major facilitator Superfamily
GBN68_12215	COG0596	Alpha beta hydrolase
GBN68_12220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBN68_12225	COG0183	Belongs to the thiolase family
GBN68_12230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GBN68_12235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GBN68_12240	COG1414	Transcriptional regulator
GBN68_12250	COG1113	amino acid transport
GBN68_12260	COG3724	N-succinylarginine dihydrolase activity
GBN68_12265	COG1012	belongs to the aldehyde dehydrogenase family
GBN68_12270	COG3138	arginine N-succinyltransferase
GBN68_12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GBN68_12285	COG1522	sequence-specific DNA binding
GBN68_12300	COG1012	belongs to the aldehyde dehydrogenase family
GBN68_12305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GBN68_12315	COG1113	amino acid transport
GBN68_12335	COG1294	oxidase, subunit
GBN68_12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GBN68_12355	COG1346	cytolysis
GBN68_12375	COG1522	sequence-specific DNA binding
GBN68_12395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GBN68_12415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GBN68_12420	COG0583	DNA-binding transcription factor activity
GBN68_12425	COG4221	oxidoreductase activity
GBN68_12445	COG3177	Filamentation induced by cAMP protein fic
GBN68_12450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GBN68_12485	COG0642	Histidine kinase
GBN68_12500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GBN68_12525	COG2816	NAD+ diphosphatase activity
GBN68_12530	COG3046	protein related to deoxyribodipyrimidine photolyase
GBN68_12590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GBN68_12605	COG2814	Major facilitator Superfamily
GBN68_12610	COG1024	Enoyl-CoA hydratase
GBN68_12615	COG1012	belongs to the aldehyde dehydrogenase family
GBN68_12620	COG1022	Amp-dependent synthetase and ligase
GBN68_12620	COG3320	Male sterility
GBN68_12625	COG1960	acyl-CoA dehydrogenase activity
GBN68_12685	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GBN68_12695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GBN68_12700	COG1335	isochorismatase
GBN68_12730	COG1902	pentaerythritol trinitrate reductase activity
GBN68_12735	COG3118	belongs to the thioredoxin family
GBN68_12740	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_12745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GBN68_12775	COG1414	Transcriptional regulator
GBN68_12780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GBN68_12785	COG1414	Transcriptional regulator
GBN68_12805	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GBN68_12920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GBN68_12925	COG2814	Major facilitator Superfamily
GBN68_12930	COG1566	PFAM secretion protein HlyD family protein
GBN68_12935	COG2050	protein possibly involved in aromatic compounds catabolism
GBN68_12950	COG1090	epimerase
GBN68_12960	COG4251	negative regulation of phosphorylation
GBN68_12960	COG3706	GGDEF domain
GBN68_12960	COG2203	Gaf domain
GBN68_12960	COG5001	Diguanylate cyclase
GBN68_12965	COG0420	3'-5' exonuclease activity
GBN68_12995	COG0735	belongs to the Fur family
GBN68_13000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBN68_13005	COG2914	Belongs to the UPF0125 (RnfH) family
GBN68_13020	COG0121	glutamine amidotransferase
GBN68_13035	COG0756	dUTP diphosphatase activity
GBN68_13040	COG0210	DNA helicase
GBN68_13045	COG2885	chlorophyll binding
GBN68_13050	COG0204	Acyl-transferase
GBN68_13060	COG0850	regulation of cytokinetic process
GBN68_13065	COG2894	cell division
GBN68_13070	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GBN68_13085	COG1674	ftsk spoiiie
GBN68_13085	COG0531	amino acid
GBN68_13090	COG0492	ferredoxin-NADP+ reductase activity
GBN68_13095	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GBN68_13105	COG0456	acetyltransferase
GBN68_13155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GBN68_13170	COG1981	membrane
GBN68_13180	COG1113	amino acid transport
GBN68_13185	COG0251	oxidation-reduction process
GBN68_13225	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBN68_13250	COG2132	Multicopper oxidase
GBN68_13260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GBN68_13295	COG1968	undecaprenyl-diphosphatase activity
GBN68_13300	COG1214	PFAM Peptidase M22, glycoprotease
GBN68_13305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GBN68_13310	COG0494	nUDIX hydrolase
GBN68_13360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBN68_13370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GBN68_13395	COG0693	protein deglycase activity
GBN68_13410	COG2814	Major facilitator Superfamily
GBN68_13445	COG2199	diguanylate cyclase activity
GBN68_13475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GBN68_13480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBN68_13500	COG0450	alkyl hydroperoxide reductase
GBN68_13520	COG0285	dihydrofolate synthase activity
GBN68_13550	COG3083	sulfuric ester hydrolase activity
GBN68_13575	COG4206	TonB-dependent receptor
GBN68_13580	COG2096	Adenosyltransferase
GBN68_13600	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GBN68_13605	COG2315	Protein conserved in bacteria
GBN68_13610	COG1113	amino acid transport
GBN68_13615	COG0745	RESPONSE REGULATOR receiver
GBN68_13620	COG2205	protein histidine kinase activity
GBN68_13630	COG1960	acyl-CoA dehydrogenase activity
GBN68_13635	COG1960	acyl-CoA dehydrogenase activity
GBN68_13640	COG3223	Belongs to the PsiE family
GBN68_13670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GBN68_13685	COG1215	transferase activity, transferring glycosyl groups
GBN68_13735	COG0438	transferase activity, transferring glycosyl groups
GBN68_13765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GBN68_13770	COG5002	protein histidine kinase activity
GBN68_13810	COG0582	viral genome integration into host DNA
GBN68_13820	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GBN68_13830	COG1704	LemA family
GBN68_13840	COG1862	Preprotein translocase
GBN68_13865	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GBN68_13885	COG1426	Protein conserved in bacteria
GBN68_13945	COG0440	acetolactate synthase activity
GBN68_13950	COG0028	Belongs to the TPP enzyme family
GBN68_13975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBN68_13980	COG1136	(ABC) transporter
GBN68_13980	COG0577	efflux transmembrane transporter activity
GBN68_13985	COG1538	Outer membrane efflux protein
GBN68_14010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GBN68_14015	COG1162	GTPase activity
GBN68_14040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GBN68_14050	COG3781	membrane
GBN68_14055	COG0613	PHP domain protein
GBN68_14065	COG2350	Protein conserved in bacteria
GBN68_14085	COG1666	GTP binding
GBN68_14100	COG1607	acyl-coa hydrolase
GBN68_14160	COG1183	phosphatidylcholine synthase activity
GBN68_14165	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GBN68_14190	COG0039	L-malate dehydrogenase activity
GBN68_14200	COG0739	heme binding
GBN68_14200	COG0741	lytic transglycosylase activity
GBN68_14200	COG1196	nuclear chromosome segregation
GBN68_14205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GBN68_14210	COG1702	phosphate starvation-inducible protein PhoH
GBN68_14215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBN68_14225	COG4773	Receptor
GBN68_14250	COG3706	GGDEF domain
GBN68_14265	COG1295	ribonuclease BN
GBN68_14280	COG0179	Fumarylacetoacetate (FAA) hydrolase
GBN68_14310	COG0557	exoribonuclease II activity
GBN68_14315	COG2720	vancomycin resistance protein
GBN68_14320	COG0339	signal peptide processing
GBN68_14325	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GBN68_14355	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GBN68_14360	COG1960	acyl-CoA dehydrogenase activity
GBN68_14365	COG2267	carboxylic ester hydrolase activity
GBN68_14370	COG2072	flavoprotein involved in K transport
GBN68_14375	COG0203	ribosomal protein L17
GBN68_14380	COG0202	RNA polymerase activity
GBN68_14395	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBN68_14420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GBN68_14430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GBN68_14435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GBN68_14485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GBN68_14500	COG0088	Forms part of the polypeptide exit tunnel
GBN68_14505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GBN68_14525	COG0433	COG0433 Predicted ATPase
GBN68_14535	COG1959	2 iron, 2 sulfur cluster binding
GBN68_14550	COG1301	dicarboxylic acid transport
GBN68_14555	COG1946	Acyl-CoA thioesterase
GBN68_14560	COG2937	Belongs to the GPAT DAPAT family
GBN68_14580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GBN68_14585	COG1040	competence protein
GBN68_14600	COG0598	Magnesium transport protein CorA
GBN68_14610	COG2854	intermembrane phospholipid transfer
GBN68_14615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GBN68_14620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GBN68_14625	COG1127	ABC transporter
GBN68_14630	COG0513	Belongs to the DEAD box helicase family
GBN68_14650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GBN68_14655	COG0408	coproporphyrinogen oxidase activity
GBN68_14675	COG1960	acyl-CoA dehydrogenase activity
GBN68_14695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GBN68_14705	COG0534	Mate efflux family protein
GBN68_14715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GBN68_14720	COG0254	rRNA binding
GBN68_14725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GBN68_14740	COG2226	methyltransferase
GBN68_14750	COG1192	Involved in chromosome partitioning
GBN68_14755	COG0628	permease
GBN68_14760	COG2032	superoxide dismutase activity
GBN68_14765	COG1289	transmembrane transporter activity
GBN68_14770	COG2814	Major facilitator Superfamily
GBN68_14795	COG0277	FAD linked oxidase domain protein
GBN68_14800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GBN68_14805	COG5006	permease, DMT superfamily
GBN68_14825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBN68_14830	COG5380	lipid catabolic process
GBN68_14845	COG0335	large ribosomal subunit rRNA binding
GBN68_14855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GBN68_14860	COG0228	four-way junction DNA binding
GBN68_14905	COG0194	GDP metabolic process
GBN68_14910	COG1758	RNA polymerase activity
GBN68_14915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBN68_14970	COG2194	sulfuric ester hydrolase activity
GBN68_15005	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GBN68_15010	COG1704	LemA family
GBN68_15020	COG0493	'glutamate synthase
GBN68_15025	COG0067	glutamate synthase
GBN68_15025	COG0069	glutamate synthase activity
GBN68_15025	COG0070	glutamate synthase
GBN68_15075	COG2226	methyltransferase
GBN68_15085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GBN68_15090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBN68_15110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GBN68_15125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBN68_15145	COG0488	(ABC) transporter
GBN68_15150	COG2873	o-acetylhomoserine
GBN68_15155	COG4221	oxidoreductase activity
GBN68_15185	COG0427	acetyl-CoA hydrolase
GBN68_15220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GBN68_15255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GBN68_15260	COG0531	amino acid
GBN68_15275	COG1278	Cold shock
GBN68_15280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GBN68_15305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GBN68_15325	COG3158	transport of potassium into the cell
GBN68_15350	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
GBN68_15375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBN68_15380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBN68_15395	COG1301	dicarboxylic acid transport
GBN68_15400	COG0583	DNA-binding transcription factor activity
GBN68_15410	COG0629	single-stranded DNA binding
GBN68_15415	COG2814	Major facilitator Superfamily
GBN68_15425	COG0351	phosphomethylpyrimidine kinase
GBN68_15425	COG0352	thiamine-phosphate diphosphorylase activity
GBN68_15425	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GBN68_15450	COG3706	GGDEF domain
GBN68_15460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GBN68_15470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GBN68_15475	COG3162	membrane
GBN68_15480	COG0784	Response regulator, receiver
GBN68_15480	COG2205	protein histidine kinase activity
GBN68_15495	COG0431	NADPH-dependent FMN reductase
GBN68_15510	COG1028	Short-chain dehydrogenase reductase Sdr
GBN68_15515	COG0307	riboflavin synthase, alpha
GBN68_15520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GBN68_15525	COG0668	transmembrane transport
GBN68_15530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GBN68_15535	COG1519	Transferase
GBN68_15540	COG1902	pentaerythritol trinitrate reductase activity
GBN68_15565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GBN68_15590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBN68_15590	COG0426	domain, Protein
GBN68_15595	COG2119	membrane
GBN68_15625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GBN68_15635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GBN68_15645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GBN68_15655	COG0189	ligase activity
GBN68_15660	COG0386	Belongs to the glutathione peroxidase family
GBN68_15665	COG1846	Transcriptional regulator
GBN68_15680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GBN68_15690	COG0708	Exodeoxyribonuclease III
GBN68_15695	COG1393	Belongs to the ArsC family
GBN68_15710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GBN68_15795	COG3150	esterase
GBN68_15805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GBN68_15810	COG2918	glutathione biosynthetic process
GBN68_15825	COG2733	membrane
GBN68_15830	COG0436	Aminotransferase
GBN68_15835	COG0534	Mate efflux family protein
GBN68_15905	COG0385	Bile acid
GBN68_15910	COG1335	isochorismatase
GBN68_15920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBN68_15940	COG4215	(ABC) transporter
GBN68_15945	COG4160	amino acid transport
GBN68_15955	COG1522	sequence-specific DNA binding
GBN68_15965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GBN68_15970	COG2983	Belongs to the UPF0260 family
GBN68_15975	COG5487	UPF0391 membrane protein
GBN68_16005	COG2818	Glycosylase
GBN68_16010	COG1064	alcohol dehydrogenase
GBN68_16015	COG0436	Aminotransferase
GBN68_16030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GBN68_16040	COG0484	heat shock protein binding
GBN68_16060	COG1309	transcriptional regulator
GBN68_16070	COG2233	PERMEase
GBN68_16075	COG0583	DNA-binding transcription factor activity
GBN68_16085	COG4774	siderophore transport
GBN68_16095	COG0129	dihydroxy-acid dehydratase activity
GBN68_16110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBN68_16110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBN68_16125	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GBN68_16125	COG3266	domain, Protein
GBN68_16125	COG4932	domain protein
GBN68_16145	COG0733	neurotransmitter:sodium symporter activity
GBN68_16155	COG2814	Major facilitator Superfamily
GBN68_16185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBN68_16190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GBN68_16195	COG2951	lytic endotransglycosylase activity
GBN68_16200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GBN68_16215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GBN68_16235	COG0861	Integral membrane protein TerC family
GBN68_16245	COG0754	glutathionylspermidine amidase activity
GBN68_16255	COG0402	S-adenosylhomocysteine deaminase activity
GBN68_16275	COG1230	cation diffusion facilitator family transporter
GBN68_16295	COG0706	membrane insertase activity
GBN68_16300	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GBN68_16315	COG0488	(ABC) transporter