locus-tag	class	description
EGT72_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGT72_000010	COG0592	DNA-directed DNA polymerase activity
EGT72_000020	COG0187	DNA topoisomerase II activity
EGT72_000030	COG0488	(ABC) transporter
EGT72_000090	COG0657	acetylesterase activity
EGT72_000100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGT72_000160	COG1047	Peptidyl-prolyl cis-trans
EGT72_000165	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EGT72_000170	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGT72_000175	COG0196	riboflavin kinase activity
EGT72_000190	COG1309	transcriptional regulator
EGT72_000195	COG3293	Transposase
EGT72_000200	COG1116	anion transmembrane transporter activity
EGT72_000205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGT72_000220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGT72_000225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EGT72_000225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EGT72_000255	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_000260	COG0546	phosphoglycolate phosphatase activity
EGT72_000265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGT72_000270	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGT72_000275	COG3307	-O-antigen
EGT72_000285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EGT72_000310	COG3293	Transposase
EGT72_000320	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGT72_000325	COG0728	peptidoglycan biosynthetic process
EGT72_000355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGT72_000380	COG0438	transferase activity, transferring glycosyl groups
EGT72_000385	COG0438	transferase activity, transferring glycosyl groups
EGT72_000390	COG0438	transferase activity, transferring glycosyl groups
EGT72_000395	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EGT72_000400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGT72_000410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGT72_000425	COG1091	dTDP-4-dehydrorhamnose reductase activity
EGT72_000430	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGT72_000455	COG0463	Glycosyl transferase, family 2
EGT72_000460	COG1215	transferase activity, transferring glycosyl groups
EGT72_000465	COG0438	transferase activity, transferring glycosyl groups
EGT72_000475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGT72_000480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGT72_000495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGT72_000505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGT72_000510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGT72_000520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGT72_000525	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGT72_000535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EGT72_000550	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGT72_000555	COG0583	DNA-binding transcription factor activity
EGT72_000560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGT72_000560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGT72_000565	COG1105	Belongs to the carbohydrate kinase PfkB family
EGT72_000570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGT72_000570	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGT72_000570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGT72_000575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGT72_000600	COG0271	Belongs to the BolA IbaG family
EGT72_000610	COG1192	Involved in chromosome partitioning
EGT72_000625	COG0586	Pfam SNARE associated Golgi protein
EGT72_000640	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGT72_000640	COG0519	Catalyzes the synthesis of GMP from XMP
EGT72_000695	COG0281	malic enzyme
EGT72_000715	COG5632	N-Acetylmuramoyl-L-alanine amidase
EGT72_000715	COG1388	LysM domain
EGT72_000715	COG3409	Peptidoglycan-binding domain 1 protein
EGT72_000725	COG2837	iron assimilation
EGT72_000735	COG1683	Conserved Protein
EGT72_000740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGT72_000745	COG1121	(ABC) transporter
EGT72_000795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EGT72_000840	COG0386	Belongs to the glutathione peroxidase family
EGT72_000850	COG0697	spore germination
EGT72_000860	COG0758	DNA mediated transformation
EGT72_000910	COG3293	Transposase
EGT72_000945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGT72_000955	COG2814	Major facilitator Superfamily
EGT72_000975	COG1253	flavin adenine dinucleotide binding
EGT72_000980	COG3012	SEC-C Motif Domain Protein
EGT72_000985	COG2860	membrane
EGT72_000990	COG0477	Major facilitator Superfamily
EGT72_001000	COG0318	PFAM AMP-dependent synthetase and ligase
EGT72_001015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGT72_001035	COG0606	chelatase, subunit chli
EGT72_001045	COG0347	Belongs to the P(II) protein family
EGT72_001050	COG0004	ammonium transporteR
EGT72_001060	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGT72_001060	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGT72_001075	COG0586	Pfam SNARE associated Golgi protein
EGT72_001095	COG0795	lipopolysaccharide-transporting ATPase activity
EGT72_001100	COG0795	lipopolysaccharide-transporting ATPase activity
EGT72_001105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGT72_001110	COG0793	Belongs to the peptidase S41A family
EGT72_001125	COG2197	response regulator
EGT72_001130	COG1686	Belongs to the peptidase S11 family
EGT72_001135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGT72_001145	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGT72_001150	COG4974	Belongs to the 'phage' integrase family
EGT72_001170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EGT72_001175	COG0772	Belongs to the SEDS family
EGT72_001180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGT72_001185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGT72_001190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGT72_001200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGT72_001210	COG1538	Outer membrane efflux protein
EGT72_001230	COG3275	phosphorelay sensor kinase activity
EGT72_001240	COG0181	hydroxymethylbilane synthase activity
EGT72_001260	COG0824	Thioesterase
EGT72_001290	COG0546	phosphoglycolate phosphatase activity
EGT72_001320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EGT72_001340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EGT72_001345	COG0081	regulation of translation
EGT72_001350	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EGT72_001355	COG0222	ribosome binding
EGT72_001360	COG0085	RNA polymerase activity
EGT72_001365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EGT72_001390	COG2056	Na+-H+ antiporter family
EGT72_001395	COG3047	cAMP biosynthetic process
EGT72_001405	COG0326	Molecular chaperone. Has ATPase activity
EGT72_001435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGT72_001515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGT72_001545	COG1289	transmembrane transporter activity
EGT72_001560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGT72_001565	COG1678	Uncharacterized ACR, COG1678
EGT72_001570	COG0497	DNA recombination
EGT72_001580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGT72_001590	COG0237	dephospho-CoA kinase activity
EGT72_001650	COG0195	Participates in both transcription termination and antitermination
EGT72_001660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EGT72_001665	COG1320	monovalent cation:proton antiporter activity
EGT72_001670	COG2212	antiporter activity
EGT72_001675	COG1863	multisubunit Na H antiporter MnhE subunit
EGT72_001680	COG0651	ATP synthesis coupled electron transport
EGT72_001685	COG1006	Multisubunit Na H antiporter MnhC subunit
EGT72_001690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGT72_001690	COG2111	Na H antiporter
EGT72_001695	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGT72_001705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGT72_001720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGT72_001750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGT72_001755	COG1074	ATP-dependent DNA helicase activity
EGT72_001760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGT72_001765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGT72_001775	COG1185	polyribonucleotide nucleotidyltransferase activity
EGT72_001810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EGT72_001820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGT72_001840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGT72_001845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGT72_001850	COG4535	Mg2 and Co2 transporter CorC
EGT72_001855	COG0425	Belongs to the sulfur carrier protein TusA family
EGT72_001870	COG3220	belongs to the UPF0276 family
EGT72_001880	COG1595	DNA-templated transcription, initiation
EGT72_001890	COG0644	oxidoreductase
EGT72_001890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EGT72_001900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGT72_001910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EGT72_001915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGT72_001920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EGT72_001930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGT72_001930	COG0493	'glutamate synthase
EGT72_001945	COG2226	methyltransferase
EGT72_001960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGT72_001985	COG0751	glycine-tRNA ligase activity
EGT72_002005	COG1983	PspC domain protein
EGT72_002030	COG0318	PFAM AMP-dependent synthetase and ligase
EGT72_002035	COG1530	ribonuclease E activity
EGT72_002040	COG0564	pseudouridine synthase activity
EGT72_002055	COG0583	DNA-binding transcription factor activity
EGT72_002070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EGT72_002090	COG1960	acyl-CoA dehydrogenase activity
EGT72_002105	COG1280	lysine exporter protein (LysE YggA)
EGT72_002140	COG0583	DNA-binding transcription factor activity
EGT72_002150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EGT72_002165	COG0473	3-isopropylmalate dehydrogenase activity
EGT72_002225	COG1560	Kdo2-lipid A biosynthetic process
EGT72_002230	COG0488	(ABC) transporter
EGT72_002235	COG2900	Belongs to the SlyX family
EGT72_002280	COG0210	DNA helicase
EGT72_002305	COG4651	solute:proton antiporter activity
EGT72_002305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGT72_002330	COG0788	formyltetrahydrofolate deformylase activity
EGT72_002435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGT72_002435	COG2813	Specifically methylates the guanine in position
EGT72_002445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGT72_002460	COG4774	siderophore transport
EGT72_002475	COG0740	serine-type endopeptidase activity
EGT72_002495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGT72_002495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGT72_002505	COG1917	Cupin 2, conserved barrel domain protein
EGT72_002505	COG2207	Transcriptional regulator
EGT72_002535	COG0280	phosphate acetyltransferase
EGT72_002535	COG0857	belongs to the CobB CobQ family
EGT72_002540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGT72_002550	COG2267	carboxylic ester hydrolase activity
EGT72_002565	COG0793	Belongs to the peptidase S41A family
EGT72_002575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGT72_002590	COG0084	hydrolase, TatD family'
EGT72_002600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGT72_002620	COG4372	Transposase
EGT72_002630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGT72_002640	COG2814	Major facilitator Superfamily
EGT72_002665	COG0004	ammonium transporteR
EGT72_002680	COG3622	Belongs to the hyi family
EGT72_002685	COG2084	Dehydrogenase
EGT72_002690	COG1024	Enoyl-CoA hydratase
EGT72_002695	COG0784	Response regulator, receiver
EGT72_002695	COG5002	protein histidine kinase activity
EGT72_002695	COG2205	protein histidine kinase activity
EGT72_002700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGT72_002715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGT72_002725	COG3956	TIGRFAM MazG family protein
EGT72_002730	COG1555	photosystem II stabilization
EGT72_002735	COG0617	tRNA 3'-terminal CCA addition
EGT72_002740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGT72_002750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EGT72_002755	COG1660	Displays ATPase and GTPase activities
EGT72_002765	COG3028	Belongs to the UPF0307 family
EGT72_002770	COG0318	PFAM AMP-dependent synthetase and ligase
EGT72_002790	COG0625	glutathione transferase activity
EGT72_002800	COG1238	metal cluster binding
EGT72_002845	COG0072	phenylalanine-tRNA ligase activity
EGT72_002870	COG0248	Ppx GppA phosphatase
EGT72_002880	COG0037	tRNA processing
EGT72_002895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGT72_002895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGT72_002940	COG1764	response to oxidative stress
EGT72_002945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGT72_002955	COG2208	phosphoserine phosphatase activity
EGT72_002960	COG2853	Lipoprotein
EGT72_003015	COG2969	positive regulation of protein catabolic process
EGT72_003020	COG0625	glutathione transferase activity
EGT72_003030	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGT72_003035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGT72_003045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGT72_003050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGT72_003055	COG4372	Transposase
EGT72_003090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGT72_003100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGT72_003105	COG1408	metallophosphoesterase
EGT72_003115	COG0477	Major facilitator Superfamily
EGT72_003120	COG1272	protein, Hemolysin III
EGT72_003140	COG1024	Enoyl-CoA hydratase
EGT72_003140	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGT72_003145	COG0183	Belongs to the thiolase family
EGT72_003150	COG2207	Transcriptional regulator
EGT72_003155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGT72_003170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGT72_003185	COG0183	Belongs to the thiolase family
EGT72_003200	COG0833	amino acid
EGT72_003205	COG2813	Specifically methylates the guanine in position
EGT72_003210	COG2233	PERMEase
EGT72_003215	COG1217	gtp-binding protein TYPA
EGT72_003220	COG1970	mechanosensitive ion channel activity
EGT72_003235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGT72_003245	COG3659	wide pore channel activity
EGT72_003250	COG1902	pentaerythritol trinitrate reductase activity
EGT72_003285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGT72_003335	COG0346	lactoylglutathione lyase activity
EGT72_003340	COG0564	pseudouridine synthase activity
EGT72_003360	COG3189	MarR family transcriptional regulator
EGT72_003365	COG2824	Alkylphosphonate utilization operon protein PhnA
EGT72_003375	COG3422	double-strand break repair
EGT72_003395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGT72_003415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGT72_003435	COG0730	response to heat
EGT72_003445	COG1196	nuclear chromosome segregation
EGT72_003450	COG3115	cell septum assembly
EGT72_003455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGT72_003460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGT72_003465	COG4774	siderophore transport
EGT72_003485	COG2193	ferroxidase activity
EGT72_003490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGT72_003495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGT72_003495	COG2226	methyltransferase
EGT72_003495	COG0596	Alpha beta hydrolase
EGT72_003510	COG4106	trans-aconitate 2-methyltransferase activity
EGT72_003555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGT72_003560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGT72_003570	COG0009	L-threonylcarbamoyladenylate synthase
EGT72_003575	COG3101	peptidyl-lysine hydroxylation
EGT72_003580	COG1399	metal-binding, possibly nucleic acid-binding protein
EGT72_003595	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_003605	COG1652	LysM domain
EGT72_003610	COG1802	Transcriptional regulator
EGT72_003615	COG0439	Biotin carboxylase
EGT72_003650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGT72_003670	COG0745	RESPONSE REGULATOR receiver
EGT72_003675	COG2205	protein histidine kinase activity
EGT72_003685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGT72_003705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGT72_003720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGT72_003730	COG0713	ATP synthesis coupled electron transport
EGT72_003735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGT72_003740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGT72_003750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EGT72_003755	COG1278	Cold shock
EGT72_003760	COG1278	Cold shock
EGT72_003765	COG0583	DNA-binding transcription factor activity
EGT72_003795	COG0525	valine-tRNA ligase activity
EGT72_003805	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_003820	COG0393	Putative heavy-metal-binding
EGT72_003825	COG1538	Outer membrane efflux protein
EGT72_003835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGT72_003840	COG0671	phosphoesterase, PA-phosphatase related
EGT72_003860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGT72_003870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGT72_003880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EGT72_003885	COG1648	precorrin-2 dehydrogenase activity
EGT72_003885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGT72_003890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGT72_003900	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_003910	COG0531	amino acid
EGT72_003925	COG0321	lipoyl(octanoyl) transferase activity
EGT72_003930	COG2921	Belongs to the UPF0250 family
EGT72_003965	COG0586	Pfam SNARE associated Golgi protein
EGT72_003990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGT72_004015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EGT72_004020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGT72_004050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EGT72_004065	COG0358	DNA primase activity
EGT72_004075	COG0564	pseudouridine synthase activity
EGT72_004100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGT72_004125	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGT72_004125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGT72_004140	COG0300	oxidoreductase activity
EGT72_004155	COG2009	succinate dehydrogenase
EGT72_004160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGT72_004165	COG1053	succinate dehydrogenase
EGT72_004170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGT72_004185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGT72_004195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGT72_004205	COG2268	Band 7 protein
EGT72_004220	COG2354	Protein conserved in bacteria
EGT72_004225	COG2321	neutral zinc metallopeptidase
EGT72_004265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGT72_004270	COG0505	Belongs to the CarA family
EGT72_004295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGT72_004300	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGT72_004340	COG2851	Citrate transporter
EGT72_004345	COG1253	flavin adenine dinucleotide binding
EGT72_004375	COG2239	Acts as a magnesium transporter
EGT72_004390	COG0501	Belongs to the peptidase M48B family
EGT72_004395	COG0741	lytic transglycosylase activity
EGT72_004400	COG0037	tRNA processing
EGT72_004410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EGT72_004415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGT72_004440	COG5006	permease, DMT superfamily
EGT72_004450	COG1309	transcriptional regulator
EGT72_004465	COG1741	Belongs to the pirin family
EGT72_004485	COG3739	integral membrane protein
EGT72_004500	COG3706	GGDEF domain
EGT72_004510	COG0302	gtp cyclohydrolase
EGT72_004520	COG0300	oxidoreductase activity
EGT72_004525	COG0318	PFAM AMP-dependent synthetase and ligase
EGT72_004545	COG0134	indole-3-glycerol-phosphate synthase activity
EGT72_004550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGT72_004555	COG0512	Glutamine amidotransferase of anthranilate synthase
EGT72_004570	COG0174	glutamine synthetase
EGT72_004580	COG3161	chorismate lyase activity
EGT72_004585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EGT72_004625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGT72_004635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGT72_004640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGT72_004655	COG1115	amino acid carrier protein
EGT72_004660	COG1113	amino acid transport
EGT72_004670	COG0019	diaminopimelate decarboxylase activity
EGT72_004680	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGT72_004695	COG1522	sequence-specific DNA binding
EGT72_004700	COG1280	lysine exporter protein (LysE YggA)
EGT72_004735	COG0842	Transport permease protein
EGT72_004740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGT72_004755	COG2175	clavaminate synthase activity
EGT72_004775	COG0052	Belongs to the universal ribosomal protein uS2 family
EGT72_004810	COG2951	lytic endotransglycosylase activity
EGT72_004825	COG0842	Transport permease protein
EGT72_004830	COG1131	(ABC) transporter
EGT72_004840	COG0303	'Molybdopterin
EGT72_004845	COG0315	cyclic pyranopterin monophosphate synthase activity
EGT72_004845	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGT72_004870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGT72_004880	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGT72_004885	COG4149	molybdate abc transporter
EGT72_004910	COG0235	Class ii aldolase
EGT72_004920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGT72_004930	COG3293	Transposase
EGT72_004935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGT72_004935	COG0475	glutathione-regulated potassium exporter activity
EGT72_004940	COG3706	GGDEF domain
EGT72_005000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGT72_005025	COG3634	alkyl hydroperoxide reductase activity
EGT72_005030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGT72_005035	COG0826	peptidase U32
EGT72_005070	COG1720	tRNA m6t6A37 methyltransferase activity
EGT72_005080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGT72_005095	COG0642	Histidine kinase
EGT72_005105	COG0494	nUDIX hydrolase
EGT72_005115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGT72_005120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGT72_005125	COG3139	Protein of unknown function (DUF1315)
EGT72_005135	COG1301	dicarboxylic acid transport
EGT72_005140	COG1960	acyl-CoA dehydrogenase activity
EGT72_005145	COG0693	protein deglycase activity
EGT72_005155	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EGT72_005160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGT72_005210	COG0415	Belongs to the DNA photolyase family
EGT72_005220	COG2252	PERMEase
EGT72_005225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGT72_005235	COG3038	cytochrome b561
EGT72_005250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGT72_005260	COG0527	aspartate kinase activity
EGT72_005270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGT72_005285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGT72_005305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGT72_005320	COG0667	Aldo Keto reductase
EGT72_005330	COG1765	OsmC-like protein
EGT72_005355	COG0540	Belongs to the ATCase OTCase family
EGT72_005420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGT72_005430	COG0659	secondary active sulfate transmembrane transporter activity
EGT72_005435	COG0625	glutathione transferase activity
EGT72_005440	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGT72_005465	COG2363	Small membrane protein
EGT72_005480	COG1278	Cold shock
EGT72_005485	COG0513	Belongs to the DEAD box helicase family
EGT72_005495	COG0778	Nitroreductase
EGT72_005520	COG0167	dihydroorotate dehydrogenase activity
EGT72_005550	COG4783	chaperone-mediated protein folding
EGT72_005555	COG1610	YqeY-like protein
EGT72_005585	COG0515	serine threonine protein kinase
EGT72_005585	COG2815	serine threonine protein kinase
EGT72_005625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGT72_005635	COG1643	Atp-dependent helicase
EGT72_005655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGT72_005655	COG1116	anion transmembrane transporter activity
EGT72_005665	COG2223	nitrite transmembrane transporter activity
EGT72_005670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGT72_005675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGT72_005680	COG0243	molybdopterin cofactor binding
EGT72_005690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGT72_005725	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGT72_005730	COG0406	alpha-ribazole phosphatase activity
EGT72_005740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGT72_005740	COG0517	IMP dehydrogenase activity
EGT72_005745	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGT72_005755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGT72_005760	COG1137	ATPase activity
EGT72_005800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGT72_005845	COG2011	ABC-type metal ion transport system permease component
EGT72_005850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGT72_005870	COG0151	Belongs to the GarS family
EGT72_005875	COG0138	bifunctional purine biosynthesis protein purh
EGT72_005880	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGT72_005910	COG0445	tRNA wobble uridine modification
EGT72_005925	COG2308	Evidence 4 Homologs of previously reported genes of
EGT72_005935	COG1305	Transglutaminase-like
EGT72_005950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGT72_005955	COG0305	Participates in initiation and elongation during chromosome replication
EGT72_005970	COG0360	Binds together with S18 to 16S ribosomal RNA
EGT72_005990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGT72_005995	COG1845	cytochrome c oxidase, subunit III
EGT72_006000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGT72_006005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGT72_006035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGT72_006050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EGT72_006055	COG2890	protein-(glutamine-N5) methyltransferase activity
EGT72_006060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGT72_006065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGT72_006095	COG1960	acyl-CoA dehydrogenase activity
EGT72_006100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGT72_006115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGT72_006140	COG0729	surface antigen
EGT72_006195	COG1113	amino acid transport
EGT72_006220	COG0024	Methionine aminopeptidase
EGT72_006225	COG0583	DNA-binding transcription factor activity
EGT72_006230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGT72_006245	COG3852	Histidine kinase
EGT72_006265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGT72_006270	COG0575	Belongs to the CDS family
EGT72_006285	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGT72_006305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGT72_006320	COG2137	regulation of response to DNA damage stimulus
EGT72_006325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EGT72_006330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGT72_006335	COG1011	Hydrolase
EGT72_006390	COG0702	epimerase
EGT72_006395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGT72_006430	COG1902	pentaerythritol trinitrate reductase activity
EGT72_006430	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGT72_006465	COG0583	DNA-binding transcription factor activity
EGT72_006485	COG0148	phosphopyruvate hydratase activity
EGT72_006500	COG0772	Belongs to the SEDS family
EGT72_006515	COG0579	oxidoreductase
EGT72_006525	COG1012	belongs to the aldehyde dehydrogenase family
EGT72_006530	COG1309	transcriptional regulator
EGT72_006535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGT72_006550	COG4890	Cyd operon protein YbgT
EGT72_006555	COG1294	oxidase, subunit
EGT72_006570	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGT72_006580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGT72_006600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGT72_006605	COG0569	domain protein
EGT72_006615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGT72_006620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGT72_006645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGT72_006650	COG0542	response to heat
EGT72_006680	COG0372	Belongs to the citrate synthase family
EGT72_006710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGT72_006715	COG0730	response to heat
EGT72_006740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGT72_006745	COG1944	ATP diphosphatase activity
EGT72_006750	COG2207	Transcriptional regulator
EGT72_006755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGT72_006770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGT72_006800	COG2223	nitrite transmembrane transporter activity
EGT72_006815	COG1346	cytolysis
EGT72_006820	COG1380	Effector of murein hydrolase LrgA
EGT72_006825	COG0583	DNA-binding transcription factor activity
EGT72_006830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGT72_006860	COG0582	viral genome integration into host DNA
EGT72_007065	COG4383	Mu-like prophage protein gp29
EGT72_007095	COG4387	Mu-like prophage protein GP36
EGT72_007190	COG3772	lysozyme
EGT72_007215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGT72_007235	COG1960	acyl-CoA dehydrogenase activity
EGT72_007290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGT72_007295	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EGT72_007320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGT72_007330	COG2814	Major facilitator Superfamily
EGT72_007345	COG1132	(ABC) transporter
EGT72_007355	COG0668	transmembrane transport
EGT72_007365	COG3122	Protein conserved in bacteria
EGT72_007385	COG0640	Transcriptional regulator
EGT72_007390	COG0596	Alpha beta hydrolase
EGT72_007395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGT72_007400	COG1335	isochorismatase
EGT72_007405	COG0251	oxidation-reduction process
EGT72_007410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGT72_007415	COG2233	PERMEase
EGT72_007425	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGT72_007435	COG0183	Belongs to the thiolase family
EGT72_007440	COG0583	DNA-binding transcription factor activity
EGT72_007455	COG0439	Biotin carboxylase
EGT72_007470	COG0511	ligase activity, forming carbon-carbon bonds
EGT72_007480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGT72_007485	COG0183	Belongs to the thiolase family
EGT72_007490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGT72_007495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGT72_007500	COG3135	benzoate transporter
EGT72_007505	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_007510	COG0633	Ferredoxin
EGT72_007510	COG0543	2 iron, 2 sulfur cluster binding
EGT72_007515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EGT72_007520	COG4638	Rieske (2fe-2S)
EGT72_007530	COG4829	muconolactone delta-isomerase
EGT72_007535	COG4948	Mandelate Racemase Muconate Lactonizing
EGT72_007540	COG0583	DNA-binding transcription factor activity
EGT72_007545	COG2814	Major facilitator Superfamily
EGT72_007635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGT72_007640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGT72_007645	COG0022	dehydrogenase e1 component
EGT72_007650	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGT72_007655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGT72_007665	COG1063	alcohol dehydrogenase
EGT72_007755	COG4372	Transposase
EGT72_007945	COG0596	Alpha beta hydrolase
EGT72_008010	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGT72_008020	COG2826	transposase and inactivated derivatives, IS30 family
EGT72_008035	COG0864	Transcriptional regulator
EGT72_008065	COG2814	Major facilitator Superfamily
EGT72_008075	COG2199	diguanylate cyclase activity
EGT72_008120	COG1960	acyl-CoA dehydrogenase activity
EGT72_008125	COG1960	acyl-CoA dehydrogenase activity
EGT72_008185	COG0552	protein localization to endoplasmic reticulum
EGT72_008190	COG0612	Peptidase, M16
EGT72_008215	COG0517	IMP dehydrogenase activity
EGT72_008215	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGT72_008225	COG0133	tryptophan synthase activity
EGT72_008235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGT72_008250	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGT72_008255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGT72_008290	COG0537	adenosine 5'-monophosphoramidase activity
EGT72_008315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGT72_008320	COG0776	regulation of translation
EGT72_008335	COG1959	2 iron, 2 sulfur cluster binding
EGT72_008345	COG0822	iron-sulfur transferase activity
EGT72_008350	COG0316	Belongs to the HesB IscA family
EGT72_008380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGT72_008395	COG3293	Transposase
EGT72_008400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGT72_008410	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGT72_008410	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGT72_008410	COG0506	proline dehydrogenase activity
EGT72_008440	COG3781	membrane
EGT72_008445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGT72_008455	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGT72_008480	COG0697	spore germination
EGT72_008495	COG0126	phosphoglycerate kinase activity
EGT72_008505	COG0424	maF-like protein
EGT72_008520	COG2850	peptidyl-arginine hydroxylation
EGT72_008525	COG4585	Histidine kinase
EGT72_008530	COG2197	response regulator
EGT72_008535	COG0069	glutamate synthase activity
EGT72_008555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGT72_008560	COG1454	alcohol dehydrogenase
EGT72_008565	COG0824	Thioesterase
EGT72_008570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGT72_008590	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_008595	COG0183	Belongs to the thiolase family
EGT72_008615	COG0583	DNA-binding transcription factor activity
EGT72_008620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGT72_008630	COG3135	benzoate transporter
EGT72_008635	COG1309	transcriptional regulator
EGT72_008640	COG2076	Multidrug Resistance protein
EGT72_008655	COG0589	response to stress
EGT72_008665	COG0308	aminopeptidase N
EGT72_008690	COG1253	flavin adenine dinucleotide binding
EGT72_008710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGT72_008715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGT72_008730	COG2431	L-lysine efflux transmembrane transporter activity
EGT72_008745	COG0776	regulation of translation
EGT72_008765	COG0590	tRNA wobble adenosine to inosine editing
EGT72_008775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EGT72_008810	COG0084	hydrolase, TatD family'
EGT72_008830	COG1663	tetraacyldisaccharide 4'-kinase activity
EGT72_008835	COG1132	(ABC) transporter
EGT72_008845	COG0811	peptide transport
EGT72_008850	COG1475	DNA binding
EGT72_008855	COG1192	Involved in chromosome partitioning
EGT72_008865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGT72_008870	COG3178	'Phosphotransferase
EGT72_008880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGT72_008885	COG1923	regulation of RNA biosynthetic process
EGT72_008895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGT72_008900	COG0802	atpase or kinase
EGT72_008905	COG0564	pseudouridine synthase activity
EGT72_008920	COG1187	pseudouridine synthase activity
EGT72_008925	COG2707	UPF0756 membrane protein
EGT72_008930	COG2814	Major facilitator Superfamily
EGT72_008935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGT72_008940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGT72_008950	COG1454	alcohol dehydrogenase
EGT72_008970	COG0531	amino acid
EGT72_008975	COG4303	Ethanolamine ammonia lyase large subunit
EGT72_008980	COG4302	ethanolamine ammonia-lyase activity
EGT72_008990	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_009000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGT72_009000	COG0519	Catalyzes the synthesis of GMP from XMP
EGT72_009005	COG2353	YceI-like domain
EGT72_009010	COG0456	acetyltransferase
EGT72_009020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGT72_009025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EGT72_009075	COG0352	thiamine-phosphate diphosphorylase activity
EGT72_009110	COG0612	Peptidase, M16
EGT72_009120	COG1823	symporter activity
EGT72_009125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGT72_009165	COG2351	hydroxyisourate hydrolase activity
EGT72_009175	COG1686	Belongs to the peptidase S11 family
EGT72_009180	COG1252	NADH dehydrogenase
EGT72_009185	COG1047	Peptidyl-prolyl cis-trans
EGT72_009190	COG1254	Belongs to the acylphosphatase family
EGT72_009195	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGT72_009195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGT72_009215	COG0318	PFAM AMP-dependent synthetase and ligase
EGT72_009220	COG2819	hydrolase of the alpha beta superfamily
EGT72_009250	COG4372	Transposase
EGT72_009265	COG3293	Transposase
EGT72_009270	COG0204	Acyl-transferase
EGT72_009305	COG1464	Belongs to the NlpA lipoprotein family
EGT72_009310	COG1464	Belongs to the NlpA lipoprotein family
EGT72_009315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGT72_009320	COG2011	ABC-type metal ion transport system permease component
EGT72_009325	COG0012	GTP binding
EGT72_009350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGT72_009365	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EGT72_009385	COG0386	Belongs to the glutathione peroxidase family
EGT72_009390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGT72_009395	COG0436	Aminotransferase
EGT72_009415	COG3634	alkyl hydroperoxide reductase activity
EGT72_009440	COG2070	2-Nitropropane dioxygenase
EGT72_009485	COG3293	Transposase
EGT72_009525	COG1309	transcriptional regulator
EGT72_009550	COG0842	Transport permease protein
EGT72_009570	COG0783	Belongs to the Dps family
EGT72_009575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGT72_009605	COG0745	RESPONSE REGULATOR receiver
EGT72_009610	COG0642	Histidine kinase
EGT72_009625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGT72_009675	COG2816	NAD+ diphosphatase activity
EGT72_009680	COG3046	protein related to deoxyribodipyrimidine photolyase
EGT72_009700	COG2351	hydroxyisourate hydrolase activity
EGT72_009730	COG2433	Pfam Transposase IS66
EGT72_009785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGT72_009795	COG0582	viral genome integration into host DNA
EGT72_009815	COG0714	Associated with various cellular activities
EGT72_009820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGT72_009825	COG2879	small protein
EGT72_009830	COG1966	Carbon starvation protein
EGT72_009835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EGT72_009855	COG0254	rRNA binding
EGT72_009875	COG1067	ATP-dependent peptidase activity
EGT72_009880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGT72_009885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGT72_009890	COG0616	signal peptide processing
EGT72_009895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGT72_009905	COG0573	inorganic phosphate transmembrane transporter activity
EGT72_009910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGT72_009915	COG0076	glutamate decarboxylase activity
EGT72_009920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGT72_009935	COG0671	phosphoesterase, PA-phosphatase related
EGT72_009940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EGT72_009950	COG1733	regulation of RNA biosynthetic process
EGT72_009985	COG0556	nucleotide-excision repair
EGT72_010000	COG2199	diguanylate cyclase activity
EGT72_010010	COG0436	Aminotransferase
EGT72_010050	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGT72_010055	COG1381	Involved in DNA repair and RecF pathway recombination
EGT72_010065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGT72_010080	COG0681	Belongs to the peptidase S26 family
EGT72_010095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGT72_010115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGT72_010125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGT72_010140	COG4208	sulfate ABC transporter
EGT72_010145	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGT72_010150	COG0583	DNA-binding transcription factor activity
EGT72_010170	COG0602	queuosine metabolic process
EGT72_010175	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGT72_010190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGT72_010200	COG0583	DNA-binding transcription factor activity
EGT72_010205	COG2353	YceI-like domain
EGT72_010210	COG1051	belongs to the nudix hydrolase family
EGT72_010210	COG1056	cytidyltransferase-related domain
EGT72_010215	COG1024	Enoyl-CoA hydratase
EGT72_010220	COG0778	Nitroreductase
EGT72_010225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGT72_010240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGT72_010240	COG0047	phosphoribosylformylglycinamidine synthase activity
EGT72_010255	COG2255	four-way junction helicase activity
EGT72_010280	COG0824	Thioesterase
EGT72_010300	COG0823	Involved in the tonB-independent uptake of proteins
EGT72_010320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGT72_010350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EGT72_010355	COG0628	permease
EGT72_010360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EGT72_010365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGT72_010385	COG0658	competence protein
EGT72_010385	COG2333	competence protein COMEC
EGT72_010390	COG1136	(ABC) transporter
EGT72_010395	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGT72_010410	COG1671	Belongs to the UPF0178 family
EGT72_010425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGT72_010430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGT72_010490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGT72_010495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGT72_010500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGT72_010510	COG0280	phosphate acetyltransferase
EGT72_010510	COG0281	malic enzyme
EGT72_010535	COG1773	rubredoxin
EGT72_010540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGT72_010585	COG1024	Enoyl-CoA hydratase
EGT72_010645	COG1902	pentaerythritol trinitrate reductase activity
EGT72_010645	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGT72_010650	COG0277	FAD linked oxidase domain protein
EGT72_010660	COG2186	Transcriptional regulator
EGT72_010675	COG4251	negative regulation of phosphorylation
EGT72_010675	COG5001	Diguanylate cyclase
EGT72_010675	COG2203	Gaf domain
EGT72_010675	COG3706	GGDEF domain
EGT72_010680	COG0418	dihydroorotase activity
EGT72_010685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGT72_010695	COG0833	amino acid
EGT72_010720	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EGT72_010735	COG4172	Belongs to the ABC transporter superfamily
EGT72_010740	COG4239	(ABC) transporter, permease
EGT72_010745	COG4174	ABC transporter (Permease)
EGT72_010750	COG4166	transmembrane transport
EGT72_010755	COG0741	lytic transglycosylase activity
EGT72_010755	COG1388	LysM domain
EGT72_010760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGT72_010775	COG0657	acetylesterase activity
EGT72_010795	COG0583	DNA-binding transcription factor activity
EGT72_010815	COG4372	Transposase
EGT72_010860	COG1686	Belongs to the peptidase S11 family
EGT72_010865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGT72_010870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGT72_010875	COG2267	carboxylic ester hydrolase activity
EGT72_010880	COG0671	phosphoesterase, PA-phosphatase related
EGT72_010880	COG2453	phosphatase
EGT72_010895	COG4589	Belongs to the CDS family
EGT72_010910	COG2915	High frequency lysogenization protein hflD homolog
EGT72_010930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGT72_010935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGT72_010950	COG0006	proline dipeptidase activity
EGT72_010975	COG4770	biotin carboxylase activity
EGT72_010995	COG1914	H( )-stimulated, divalent metal cation uptake system
EGT72_011000	COG0583	DNA-binding transcription factor activity
EGT72_011005	COG2217	Heavy metal translocating P-type atpase
EGT72_011015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGT72_011030	COG2234	aminopeptidase activity
EGT72_011040	COG3384	dioxygenase
EGT72_011050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGT72_011055	COG2878	Part of a membrane complex involved in electron transport
EGT72_011060	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGT72_011085	COG0768	penicillin binding
EGT72_011090	COG0742	ribosomal rna small subunit methyltransferase
EGT72_011120	COG0653	protein targeting
EGT72_011155	COG1597	lipid kinase activity
EGT72_011170	COG0477	Major facilitator Superfamily
EGT72_011220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGT72_011220	COG0604	alcohol dehydrogenase
EGT72_011220	COG4221	oxidoreductase activity
EGT72_011220	COG3321	synthase
EGT72_011235	COG1695	Transcriptional regulator
EGT72_011265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGT72_011270	COG1773	rubredoxin
EGT72_011275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGT72_011285	COG0583	DNA-binding transcription factor activity
EGT72_011305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGT72_011310	COG4181	ATPase activity
EGT72_011335	COG4771	TonB-dependent receptor
EGT72_011360	COG0306	phosphate transporter
EGT72_011370	COG0539	negative regulation of cytoplasmic translation
EGT72_011390	COG2223	nitrite transmembrane transporter activity
EGT72_011395	COG2207	Transcriptional regulator
EGT72_011400	COG0242	peptide deformylase activity
EGT72_011445	COG3293	Transposase
EGT72_011460	COG4372	Transposase
EGT72_011485	COG4681	YaeQ
EGT72_011490	COG0523	cobalamin synthesis protein
EGT72_011500	COG1607	acyl-coa hydrolase
EGT72_011505	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGT72_011515	COG1115	amino acid carrier protein
EGT72_011520	COG0786	glutamate:sodium symporter activity
EGT72_011535	COG2814	Major facilitator Superfamily
EGT72_011540	COG1289	transmembrane transporter activity
EGT72_011550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGT72_011615	COG1376	ErfK ybiS ycfS ynhG family protein
EGT72_011620	COG2832	Protein of unknown function (DUF454)
EGT72_011635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGT72_011645	COG0643	Histidine kinase
EGT72_011645	COG2198	Histidine kinase
EGT72_011645	COG0784	Response regulator, receiver
EGT72_011650	COG0840	transmembrane signaling receptor activity
EGT72_011720	COG2358	TRAP transporter, solute receptor (TAXI family
EGT72_011735	COG0489	protein tyrosine kinase activity
EGT72_011760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGT72_011760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGT72_011795	COG4716	Myosin-crossreactive antigen
EGT72_011825	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGT72_011830	COG2081	HI0933 family
EGT72_011845	COG0668	transmembrane transport
EGT72_011865	COG0765	amino acid transport
EGT72_011870	COG0765	amino acid transport
EGT72_011875	COG1126	abc transporter atp-binding protein
EGT72_011885	COG0004	ammonium transporteR
EGT72_011900	COG0642	Histidine kinase
EGT72_011905	COG0745	RESPONSE REGULATOR receiver
EGT72_011930	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGT72_011945	COG0142	geranyltranstransferase activity
EGT72_011950	COG2828	Protein conserved in bacteria
EGT72_011955	COG1113	amino acid transport
EGT72_011970	COG1113	amino acid transport
EGT72_011990	COG0625	glutathione transferase activity
EGT72_012005	COG0431	NADPH-dependent FMN reductase
EGT72_012010	COG0798	PFAM Bile acid sodium symporter
EGT72_012020	COG0640	Transcriptional regulator
EGT72_012030	COG3293	Transposase
EGT72_012075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGT72_012090	COG0424	maF-like protein
EGT72_012095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGT72_012100	COG1792	Involved in formation and maintenance of cell shape
EGT72_012105	COG1077	Cell shape determining protein MreB Mrl
EGT72_012110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGT72_012120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGT72_012165	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EGT72_012185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGT72_012210	COG0640	Transcriptional regulator
EGT72_012215	COG1136	(ABC) transporter
EGT72_012225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGT72_012250	COG0582	viral genome integration into host DNA
EGT72_012260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGT72_012265	COG2814	Major facilitator Superfamily
EGT72_012270	COG1566	PFAM secretion protein HlyD family protein
EGT72_012275	COG2050	protein possibly involved in aromatic compounds catabolism
EGT72_012290	COG1090	epimerase
EGT72_012300	COG5001	Diguanylate cyclase
EGT72_012300	COG4251	negative regulation of phosphorylation
EGT72_012300	COG3706	GGDEF domain
EGT72_012300	COG2203	Gaf domain
EGT72_012305	COG0420	3'-5' exonuclease activity
EGT72_012335	COG0735	belongs to the Fur family
EGT72_012340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGT72_012345	COG2914	Belongs to the UPF0125 (RnfH) family
EGT72_012360	COG0121	glutamine amidotransferase
EGT72_012375	COG0756	dUTP diphosphatase activity
EGT72_012380	COG0210	DNA helicase
EGT72_012385	COG2885	chlorophyll binding
EGT72_012390	COG0204	Acyl-transferase
EGT72_012400	COG0850	regulation of cytokinetic process
EGT72_012410	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGT72_012425	COG1674	ftsk spoiiie
EGT72_012425	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGT72_012430	COG0492	ferredoxin-NADP+ reductase activity
EGT72_012435	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGT72_012445	COG0456	acetyltransferase
EGT72_012470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGT72_012485	COG1981	membrane
EGT72_012495	COG1113	amino acid transport
EGT72_012500	COG0251	oxidation-reduction process
EGT72_012530	COG0351	phosphomethylpyrimidine kinase
EGT72_012530	COG0352	thiamine-phosphate diphosphorylase activity
EGT72_012530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGT72_012540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGT72_012565	COG2132	Multicopper oxidase
EGT72_012575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGT72_012610	COG1968	undecaprenyl-diphosphatase activity
EGT72_012615	COG1214	PFAM Peptidase M22, glycoprotease
EGT72_012620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGT72_012625	COG0494	nUDIX hydrolase
EGT72_012660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGT72_012670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGT72_012695	COG0693	protein deglycase activity
EGT72_012710	COG2814	Major facilitator Superfamily
EGT72_012770	COG2199	diguanylate cyclase activity
EGT72_012800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGT72_012805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGT72_012835	COG0450	alkyl hydroperoxide reductase
EGT72_012855	COG0285	dihydrofolate synthase activity
EGT72_012910	COG2096	Adenosyltransferase
EGT72_012930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGT72_012935	COG2315	Protein conserved in bacteria
EGT72_012940	COG1113	amino acid transport
EGT72_012945	COG0745	RESPONSE REGULATOR receiver
EGT72_012950	COG2205	protein histidine kinase activity
EGT72_012960	COG1960	acyl-CoA dehydrogenase activity
EGT72_012965	COG1960	acyl-CoA dehydrogenase activity
EGT72_012970	COG3223	Belongs to the PsiE family
EGT72_013000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EGT72_013060	COG0438	transferase activity, transferring glycosyl groups
EGT72_013080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGT72_013085	COG5002	protein histidine kinase activity
EGT72_013095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EGT72_013105	COG1704	LemA family
EGT72_013115	COG1862	Preprotein translocase
EGT72_013140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGT72_013160	COG1426	Protein conserved in bacteria
EGT72_013220	COG0440	acetolactate synthase activity
EGT72_013225	COG0028	Belongs to the TPP enzyme family
EGT72_013250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGT72_013255	COG1136	(ABC) transporter
EGT72_013255	COG0577	efflux transmembrane transporter activity
EGT72_013285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGT72_013290	COG1162	GTPase activity
EGT72_013315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGT72_013325	COG3781	membrane
EGT72_013330	COG0613	PHP domain protein
EGT72_013340	COG2350	Protein conserved in bacteria
EGT72_013360	COG1666	GTP binding
EGT72_013375	COG1607	acyl-coa hydrolase
EGT72_013435	COG1183	phosphatidylcholine synthase activity
EGT72_013440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGT72_013465	COG0039	L-malate dehydrogenase activity
EGT72_013475	COG0739	heme binding
EGT72_013475	COG0741	lytic transglycosylase activity
EGT72_013475	COG1196	nuclear chromosome segregation
EGT72_013480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EGT72_013485	COG1702	phosphate starvation-inducible protein PhoH
EGT72_013490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EGT72_013535	COG1295	ribonuclease BN
EGT72_013550	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGT72_013580	COG0557	exoribonuclease II activity
EGT72_013585	COG2720	vancomycin resistance protein
EGT72_013590	COG0339	signal peptide processing
EGT72_013595	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGT72_013625	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGT72_013630	COG1960	acyl-CoA dehydrogenase activity
EGT72_013640	COG2072	flavoprotein involved in K transport
EGT72_013645	COG0203	ribosomal protein L17
EGT72_013650	COG0202	RNA polymerase activity
EGT72_013665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGT72_013690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EGT72_013700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EGT72_013705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EGT72_013755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGT72_013770	COG0088	Forms part of the polypeptide exit tunnel
EGT72_013775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EGT72_013795	COG0433	COG0433 Predicted ATPase
EGT72_013805	COG1959	2 iron, 2 sulfur cluster binding
EGT72_013820	COG1301	dicarboxylic acid transport
EGT72_013825	COG1946	Acyl-CoA thioesterase
EGT72_013830	COG2937	Belongs to the GPAT DAPAT family
EGT72_013875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGT72_013880	COG1040	competence protein
EGT72_013895	COG0598	Magnesium transport protein CorA
EGT72_013905	COG2854	intermembrane phospholipid transfer
EGT72_013910	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGT72_013915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGT72_013920	COG1127	ABC transporter
EGT72_013925	COG0513	Belongs to the DEAD box helicase family
EGT72_013935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EGT72_013945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGT72_013950	COG0408	coproporphyrinogen oxidase activity
EGT72_013970	COG1960	acyl-CoA dehydrogenase activity
EGT72_013990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGT72_014000	COG0534	Mate efflux family protein
EGT72_014010	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGT72_014015	COG0254	rRNA binding
EGT72_014020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGT72_014035	COG2226	methyltransferase
EGT72_014045	COG1192	Involved in chromosome partitioning
EGT72_014050	COG0628	permease
EGT72_014055	COG2032	superoxide dismutase activity
EGT72_014060	COG1289	transmembrane transporter activity
EGT72_014065	COG2814	Major facilitator Superfamily
EGT72_014090	COG0277	FAD linked oxidase domain protein
EGT72_014095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGT72_014100	COG5006	permease, DMT superfamily
EGT72_014120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGT72_014125	COG5380	lipid catabolic process
EGT72_014140	COG2433	Pfam Transposase IS66
EGT72_014165	COG4372	Transposase
EGT72_014175	COG0335	large ribosomal subunit rRNA binding
EGT72_014185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGT72_014190	COG0228	four-way junction DNA binding
EGT72_014235	COG0194	GDP metabolic process
EGT72_014240	COG1758	RNA polymerase activity
EGT72_014245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGT72_014280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGT72_014285	COG1704	LemA family
EGT72_014295	COG0493	'glutamate synthase
EGT72_014300	COG0067	glutamate synthase
EGT72_014300	COG0069	glutamate synthase activity
EGT72_014300	COG0070	glutamate synthase
EGT72_014345	COG2226	methyltransferase
EGT72_014355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGT72_014360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGT72_014380	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGT72_014395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGT72_014415	COG0488	(ABC) transporter
EGT72_014425	COG4221	oxidoreductase activity
EGT72_014455	COG4372	Transposase
EGT72_014490	COG0427	acetyl-CoA hydrolase
EGT72_014525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGT72_014560	COG1278	Cold shock
EGT72_014565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGT72_014635	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EGT72_014660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGT72_014680	COG0583	DNA-binding transcription factor activity
EGT72_014690	COG0629	single-stranded DNA binding
EGT72_014695	COG2826	transposase and inactivated derivatives, IS30 family
EGT72_014745	COG0629	single-stranded DNA binding
EGT72_014750	COG2814	Major facilitator Superfamily
EGT72_014760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGT72_014760	COG0352	thiamine-phosphate diphosphorylase activity
EGT72_014760	COG0351	phosphomethylpyrimidine kinase
EGT72_014785	COG3706	GGDEF domain
EGT72_014795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGT72_014810	COG3162	membrane
EGT72_014815	COG0784	Response regulator, receiver
EGT72_014815	COG2205	protein histidine kinase activity
EGT72_014830	COG0431	NADPH-dependent FMN reductase
EGT72_014845	COG1028	Short-chain dehydrogenase reductase Sdr
EGT72_014850	COG0307	riboflavin synthase, alpha
EGT72_014855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGT72_014860	COG0668	transmembrane transport
EGT72_014865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGT72_014870	COG1519	Transferase
EGT72_014875	COG1902	pentaerythritol trinitrate reductase activity
EGT72_014900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGT72_014935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGT72_014935	COG0426	domain, Protein
EGT72_014940	COG2119	membrane
EGT72_014970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGT72_014980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGT72_014990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGT72_015000	COG0189	ligase activity
EGT72_015005	COG0386	Belongs to the glutathione peroxidase family
EGT72_015035	COG0708	Exodeoxyribonuclease III
EGT72_015040	COG1393	Belongs to the ArsC family
EGT72_015055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGT72_015145	COG3150	esterase
EGT72_015155	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EGT72_015160	COG2918	glutathione biosynthetic process
EGT72_015175	COG2733	membrane
EGT72_015180	COG0436	Aminotransferase
EGT72_015185	COG0534	Mate efflux family protein
EGT72_015255	COG0385	Bile acid
EGT72_015260	COG1335	isochorismatase
EGT72_015265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGT72_015290	COG4160	amino acid transport
EGT72_015305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGT72_015310	COG2983	Belongs to the UPF0260 family
EGT72_015315	COG5487	UPF0391 membrane protein
EGT72_015345	COG2818	Glycosylase
EGT72_015350	COG1064	alcohol dehydrogenase
EGT72_015355	COG0436	Aminotransferase
EGT72_015370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EGT72_015380	COG0484	heat shock protein binding
EGT72_015400	COG1309	transcriptional regulator
EGT72_015410	COG2233	PERMEase
EGT72_015415	COG0583	DNA-binding transcription factor activity
EGT72_015445	COG0129	dihydroxy-acid dehydratase activity
EGT72_015465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGT72_015465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGT72_015510	COG0733	neurotransmitter:sodium symporter activity
EGT72_015550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGT72_015555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EGT72_015560	COG2951	lytic endotransglycosylase activity
EGT72_015565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGT72_015580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGT72_015605	COG0861	Integral membrane protein TerC family
EGT72_015615	COG0754	glutathionylspermidine amidase activity
EGT72_015625	COG0402	S-adenosylhomocysteine deaminase activity
EGT72_015645	COG1230	cation diffusion facilitator family transporter
EGT72_015660	COG0583	DNA-binding transcription factor activity
EGT72_015675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGT72_015680	COG0281	malic enzyme
EGT72_015690	COG0706	membrane insertase activity
EGT72_015695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EGT72_015950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGT72_015955	COG1230	cation diffusion facilitator family transporter
EGT72_015965	COG0640	Transcriptional regulator
EGT72_015975	COG0789	Transcriptional regulator
EGT72_016080	COG1192	Involved in chromosome partitioning
EGT72_016085	COG1475	DNA binding
EGT72_016295	COG0657	acetylesterase activity
EGT72_016320	COG2814	Major facilitator Superfamily
EGT72_016345	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGT72_016375	COG3657	addiction module killer protein
EGT72_016380	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGT72_016400	COG0488	(ABC) transporter
EGT72_016405	COG3173	Aminoglycoside phosphotransferase
EGT72_016550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGT72_016560	COG0673	inositol 2-dehydrogenase activity
EGT72_016665	COG2826	transposase and inactivated derivatives, IS30 family
EGT72_016675	COG2826	transposase and inactivated derivatives, IS30 family
EGT72_016825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGT72_016875	COG1525	nuclease
EGT72_016945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGT72_017045	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGT72_017070	COG3077	Addiction module antitoxin, RelB DinJ family
EGT72_017075	COG2801	Transposase and inactivated derivatives
EGT72_017095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGT72_017165	COG2814	Major facilitator Superfamily
EGT72_017180	COG3842	ATPase activity
EGT72_017185	COG1840	ABC-type Fe3 transport system, periplasmic component
EGT72_017200	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGT72_017220	COG0604	alcohol dehydrogenase
EGT72_017240	COG1063	alcohol dehydrogenase
EGT72_017255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGT72_017280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGT72_017310	COG4680	protein conserved in bacteria
EGT72_017315	COG1373	ATPase (AAA superfamily
EGT72_017325	COG0582	viral genome integration into host DNA
EGT72_017380	COG0251	oxidation-reduction process
EGT72_017395	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGT72_017400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGT72_017405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGT72_017410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EGT72_017415	COG1917	Cupin 2, conserved barrel domain protein
EGT72_017415	COG4977	sequence-specific DNA binding
EGT72_017485	COG1764	response to oxidative stress
EGT72_017490	COG1846	Transcriptional regulator
EGT72_017505	COG3842	ATPase activity
EGT72_017510	COG1840	ABC-type Fe3 transport system, periplasmic component
EGT72_017525	COG3335	DDE superfamily endonuclease
EGT72_017545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EGT72_017615	COG0515	serine threonine protein kinase
EGT72_017620	COG2116	formate transmembrane transporter activity
EGT72_017650	COG1192	Involved in chromosome partitioning
EGT72_017655	COG1475	DNA binding
EGT72_017675	COG2814	Major facilitator Superfamily
EGT72_017680	COG0583	DNA-binding transcription factor activity
EGT72_017690	COG2026	Addiction module toxin, RelE StbE family
EGT72_017695	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGT72_017715	COG2433	Pfam Transposase IS66
EGT72_017730	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGT72_017755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGT72_017760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGT72_017830	COG0789	Transcriptional regulator
EGT72_017880	COG2217	Heavy metal translocating P-type atpase
EGT72_017885	COG3174	membrane
EGT72_017890	COG2205	protein histidine kinase activity
EGT72_017905	COG2132	Multicopper oxidase
EGT72_017960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGT72_018010	COG2433	Pfam Transposase IS66
EGT72_018070	COG1937	Protein conserved in bacteria
EGT72_018110	COG2814	Major facilitator Superfamily
EGT72_018115	COG1238	metal cluster binding
EGT72_018140	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EGT72_018190	COG4115	mRNA cleavage
EGT72_018250	COG0484	heat shock protein binding