locus-tag	class	description
FYN22_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYN22_00010	COG0592	DNA-directed DNA polymerase activity
FYN22_00020	COG0187	DNA topoisomerase II activity
FYN22_00030	COG0488	(ABC) transporter
FYN22_00055	COG3385	transposase activity
FYN22_00105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYN22_00135	COG2814	Major facilitator Superfamily
FYN22_00145	COG0733	neurotransmitter:sodium symporter activity
FYN22_00165	COG3266	domain, Protein
FYN22_00165	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FYN22_00165	COG4932	domain protein
FYN22_00180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYN22_00180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYN22_00195	COG0129	dihydroxy-acid dehydratase activity
FYN22_00205	COG4774	siderophore transport
FYN22_00215	COG0583	DNA-binding transcription factor activity
FYN22_00220	COG2233	PERMEase
FYN22_00230	COG1309	transcriptional regulator
FYN22_00250	COG0484	heat shock protein binding
FYN22_00260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FYN22_00275	COG0436	Aminotransferase
FYN22_00280	COG1064	alcohol dehydrogenase
FYN22_00285	COG2818	Glycosylase
FYN22_00315	COG5487	UPF0391 membrane protein
FYN22_00320	COG2983	Belongs to the UPF0260 family
FYN22_00325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYN22_00345	COG4160	amino acid transport
FYN22_00350	COG4215	(ABC) transporter
FYN22_00375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYN22_00380	COG1335	isochorismatase
FYN22_00385	COG0385	Bile acid
FYN22_00415	COG3385	transposase activity
FYN22_00460	COG0534	Mate efflux family protein
FYN22_00465	COG0436	Aminotransferase
FYN22_00470	COG2733	membrane
FYN22_00485	COG2918	glutathione biosynthetic process
FYN22_00490	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FYN22_00500	COG3150	esterase
FYN22_00515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYN22_00530	COG0410	ABC transporter
FYN22_00565	COG3385	transposase activity
FYN22_00595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FYN22_00610	COG1393	Belongs to the ArsC family
FYN22_00615	COG0708	Exodeoxyribonuclease III
FYN22_00625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYN22_00640	COG1846	Transcriptional regulator
FYN22_00645	COG0386	Belongs to the glutathione peroxidase family
FYN22_00650	COG0189	ligase activity
FYN22_00660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYN22_00670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYN22_00680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FYN22_00705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYN22_00710	COG2119	membrane
FYN22_00715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_00715	COG0426	domain, Protein
FYN22_00740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYN22_00765	COG1902	pentaerythritol trinitrate reductase activity
FYN22_00770	COG1519	Transferase
FYN22_00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYN22_00780	COG0668	transmembrane transport
FYN22_00785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_00790	COG0307	riboflavin synthase, alpha
FYN22_00795	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_00810	COG0431	NADPH-dependent FMN reductase
FYN22_00825	COG2205	protein histidine kinase activity
FYN22_00825	COG0784	Response regulator, receiver
FYN22_00830	COG3162	membrane
FYN22_00835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYN22_00845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYN22_00855	COG3706	GGDEF domain
FYN22_00880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYN22_00880	COG0351	phosphomethylpyrimidine kinase
FYN22_00880	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_00890	COG2814	Major facilitator Superfamily
FYN22_00895	COG0629	single-stranded DNA binding
FYN22_00905	COG0583	DNA-binding transcription factor activity
FYN22_00925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYN22_00930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_00935	COG0450	alkyl hydroperoxide reductase
FYN22_00955	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYN22_00980	COG3158	transport of potassium into the cell
FYN22_01000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FYN22_01025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FYN22_01030	COG1278	Cold shock
FYN22_01045	COG0531	amino acid
FYN22_01050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYN22_01085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FYN22_01120	COG0427	acetyl-CoA hydrolase
FYN22_01125	COG2205	protein histidine kinase activity
FYN22_01130	COG0745	RESPONSE REGULATOR receiver
FYN22_01150	COG4221	oxidoreductase activity
FYN22_01160	COG0488	(ABC) transporter
FYN22_01165	COG3385	transposase activity
FYN22_01185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_01195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_01200	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_01220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYN22_01225	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FYN22_01235	COG2226	methyltransferase
FYN22_01285	COG0069	glutamate synthase activity
FYN22_01285	COG0067	glutamate synthase
FYN22_01285	COG0070	glutamate synthase
FYN22_01290	COG0493	'glutamate synthase
FYN22_01300	COG1704	LemA family
FYN22_01305	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYN22_01320	COG3307	-O-antigen
FYN22_01350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_01355	COG1758	RNA polymerase activity
FYN22_01360	COG0194	GDP metabolic process
FYN22_01405	COG0228	four-way junction DNA binding
FYN22_01410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYN22_01420	COG0335	large ribosomal subunit rRNA binding
FYN22_01435	COG5380	lipid catabolic process
FYN22_01440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYN22_01460	COG5006	permease, DMT superfamily
FYN22_01465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYN22_01470	COG0277	FAD linked oxidase domain protein
FYN22_01495	COG2814	Major facilitator Superfamily
FYN22_01500	COG1289	transmembrane transporter activity
FYN22_01505	COG2032	superoxide dismutase activity
FYN22_01510	COG0628	permease
FYN22_01515	COG1192	Involved in chromosome partitioning
FYN22_01525	COG2226	methyltransferase
FYN22_01540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYN22_01545	COG0254	rRNA binding
FYN22_01550	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYN22_01560	COG0534	Mate efflux family protein
FYN22_01570	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYN22_01595	COG1960	acyl-CoA dehydrogenase activity
FYN22_01620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYN22_01640	COG0513	Belongs to the DEAD box helicase family
FYN22_01645	COG1127	ABC transporter
FYN22_01650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYN22_01655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYN22_01660	COG2854	intermembrane phospholipid transfer
FYN22_01670	COG0598	Magnesium transport protein CorA
FYN22_01680	COG0494	nUDIX hydrolase
FYN22_01685	COG1040	competence protein
FYN22_01690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYN22_01710	COG2937	Belongs to the GPAT DAPAT family
FYN22_01715	COG1946	Acyl-CoA thioesterase
FYN22_01720	COG1301	dicarboxylic acid transport
FYN22_01735	COG1959	2 iron, 2 sulfur cluster binding
FYN22_01740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYN22_01740	COG1017	nitric oxide dioxygenase activity
FYN22_01745	COG0433	COG0433 Predicted ATPase
FYN22_01765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYN22_01770	COG0088	Forms part of the polypeptide exit tunnel
FYN22_01785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYN22_01790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYN22_01835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYN22_01840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYN22_01850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYN22_01870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYN22_01875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYN22_01880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYN22_01890	COG0202	RNA polymerase activity
FYN22_01895	COG0203	ribosomal protein L17
FYN22_01900	COG2072	flavoprotein involved in K transport
FYN22_01910	COG1960	acyl-CoA dehydrogenase activity
FYN22_01915	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYN22_01945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FYN22_01950	COG0339	signal peptide processing
FYN22_01955	COG2720	vancomycin resistance protein
FYN22_01960	COG0557	exoribonuclease II activity
FYN22_01995	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYN22_02010	COG1295	ribonuclease BN
FYN22_02025	COG3706	GGDEF domain
FYN22_02050	COG4773	Receptor
FYN22_02060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYN22_02065	COG1702	phosphate starvation-inducible protein PhoH
FYN22_02070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYN22_02075	COG0739	heme binding
FYN22_02075	COG0741	lytic transglycosylase activity
FYN22_02075	COG1196	nuclear chromosome segregation
FYN22_02085	COG0039	L-malate dehydrogenase activity
FYN22_02110	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYN22_02115	COG1183	phosphatidylcholine synthase activity
FYN22_02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_02160	COG3453	Protein conserved in bacteria
FYN22_02175	COG1607	acyl-coa hydrolase
FYN22_02190	COG1666	GTP binding
FYN22_02210	COG2350	Protein conserved in bacteria
FYN22_02220	COG0613	PHP domain protein
FYN22_02225	COG3781	membrane
FYN22_02235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYN22_02260	COG1162	GTPase activity
FYN22_02265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYN22_02290	COG1538	Outer membrane efflux protein
FYN22_02295	COG1136	(ABC) transporter
FYN22_02295	COG0577	efflux transmembrane transporter activity
FYN22_02300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_02325	COG0028	Belongs to the TPP enzyme family
FYN22_02330	COG0440	acetolactate synthase activity
FYN22_02390	COG1426	Protein conserved in bacteria
FYN22_02410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_02435	COG1862	Preprotein translocase
FYN22_02445	COG1704	LemA family
FYN22_02455	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYN22_02465	COG5002	protein histidine kinase activity
FYN22_02470	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYN22_02500	COG0438	transferase activity, transferring glycosyl groups
FYN22_02520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FYN22_02565	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYN22_02595	COG3223	Belongs to the PsiE family
FYN22_02600	COG1960	acyl-CoA dehydrogenase activity
FYN22_02605	COG1960	acyl-CoA dehydrogenase activity
FYN22_02615	COG2205	protein histidine kinase activity
FYN22_02620	COG0745	RESPONSE REGULATOR receiver
FYN22_02625	COG1113	amino acid transport
FYN22_02630	COG2315	Protein conserved in bacteria
FYN22_02635	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYN22_02655	COG2096	Adenosyltransferase
FYN22_02660	COG4206	TonB-dependent receptor
FYN22_02670	COG0133	tryptophan synthase activity
FYN22_02685	COG3083	sulfuric ester hydrolase activity
FYN22_02715	COG0285	dihydrofolate synthase activity
FYN22_02735	COG0450	alkyl hydroperoxide reductase
FYN22_02755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYN22_02760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FYN22_02790	COG2199	diguanylate cyclase activity
FYN22_02850	COG2969	positive regulation of protein catabolic process
FYN22_02855	COG0625	glutathione transferase activity
FYN22_02865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYN22_02870	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYN22_02875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYN22_02880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYN22_02885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYN22_02910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYN22_02920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYN22_02925	COG1408	metallophosphoesterase
FYN22_02935	COG0477	Major facilitator Superfamily
FYN22_02940	COG1272	protein, Hemolysin III
FYN22_02960	COG1024	Enoyl-CoA hydratase
FYN22_02960	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYN22_02965	COG0183	Belongs to the thiolase family
FYN22_02970	COG2207	Transcriptional regulator
FYN22_02975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYN22_02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_03010	COG0183	Belongs to the thiolase family
FYN22_03020	COG2885	chlorophyll binding
FYN22_03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYN22_03025	COG0833	amino acid
FYN22_03030	COG2813	Specifically methylates the guanine in position
FYN22_03035	COG2233	PERMEase
FYN22_03045	COG1970	mechanosensitive ion channel activity
FYN22_03055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_03065	COG3659	wide pore channel activity
FYN22_03070	COG1902	pentaerythritol trinitrate reductase activity
FYN22_03100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYN22_03140	COG0346	lactoylglutathione lyase activity
FYN22_03145	COG0564	pseudouridine synthase activity
FYN22_03165	COG3189	MarR family transcriptional regulator
FYN22_03170	COG2824	Alkylphosphonate utilization operon protein PhnA
FYN22_03180	COG3422	double-strand break repair
FYN22_03200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYN22_03220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYN22_03230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYN22_03240	COG0730	response to heat
FYN22_03250	COG1196	nuclear chromosome segregation
FYN22_03255	COG3115	cell septum assembly
FYN22_03260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYN22_03265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYN22_03270	COG4774	siderophore transport
FYN22_03285	COG2193	ferroxidase activity
FYN22_03290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYN22_03295	COG0596	Alpha beta hydrolase
FYN22_03295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_03295	COG2226	methyltransferase
FYN22_03310	COG4106	trans-aconitate 2-methyltransferase activity
FYN22_03340	COG4206	TonB-dependent receptor
FYN22_03380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYN22_03385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYN22_03395	COG0009	L-threonylcarbamoyladenylate synthase
FYN22_03400	COG3101	peptidyl-lysine hydroxylation
FYN22_03405	COG1399	metal-binding, possibly nucleic acid-binding protein
FYN22_03410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYN22_03420	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_03430	COG1652	LysM domain
FYN22_03435	COG1802	Transcriptional regulator
FYN22_03455	COG3501	Rhs element vgr protein
FYN22_03475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FYN22_03485	COG0745	RESPONSE REGULATOR receiver
FYN22_03490	COG2205	protein histidine kinase activity
FYN22_03500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_03520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYN22_03535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_03545	COG0713	ATP synthesis coupled electron transport
FYN22_03550	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYN22_03555	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYN22_03570	COG1278	Cold shock
FYN22_03580	COG0583	DNA-binding transcription factor activity
FYN22_03590	COG3706	GGDEF domain
FYN22_03590	COG0745	RESPONSE REGULATOR receiver
FYN22_03610	COG0525	valine-tRNA ligase activity
FYN22_03620	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_03635	COG0393	Putative heavy-metal-binding
FYN22_03640	COG1538	Outer membrane efflux protein
FYN22_03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_03655	COG0671	phosphoesterase, PA-phosphatase related
FYN22_03675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYN22_03685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYN22_03695	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYN22_03700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYN22_03700	COG1648	precorrin-2 dehydrogenase activity
FYN22_03705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FYN22_03725	COG0531	amino acid
FYN22_03740	COG0321	lipoyl(octanoyl) transferase activity
FYN22_03745	COG2921	Belongs to the UPF0250 family
FYN22_03770	COG0583	DNA-binding transcription factor activity
FYN22_03780	COG0586	Pfam SNARE associated Golgi protein
FYN22_03805	COG3385	transposase activity
FYN22_03840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYN22_03870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FYN22_03885	COG0358	DNA primase activity
FYN22_03895	COG0564	pseudouridine synthase activity
FYN22_03920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYN22_03945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYN22_03945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYN22_03965	COG2072	flavoprotein involved in K transport
FYN22_03975	COG2009	succinate dehydrogenase
FYN22_03980	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYN22_03985	COG1053	succinate dehydrogenase
FYN22_03990	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYN22_04005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_04015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYN22_04025	COG2268	Band 7 protein
FYN22_04030	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYN22_04040	COG2354	Protein conserved in bacteria
FYN22_04045	COG2321	neutral zinc metallopeptidase
FYN22_04060	COG3695	enzyme binding
FYN22_04085	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYN22_04090	COG0505	Belongs to the CarA family
FYN22_04115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYN22_04120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FYN22_04160	COG2851	Citrate transporter
FYN22_04165	COG1253	flavin adenine dinucleotide binding
FYN22_04195	COG2239	Acts as a magnesium transporter
FYN22_04210	COG0501	Belongs to the peptidase M48B family
FYN22_04215	COG0741	lytic transglycosylase activity
FYN22_04220	COG0037	tRNA processing
FYN22_04230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FYN22_04235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYN22_04265	COG1309	transcriptional regulator
FYN22_04280	COG1741	Belongs to the pirin family
FYN22_04300	COG3739	integral membrane protein
FYN22_04315	COG3706	GGDEF domain
FYN22_04325	COG0302	gtp cyclohydrolase
FYN22_04340	COG0134	indole-3-glycerol-phosphate synthase activity
FYN22_04345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYN22_04350	COG0512	Glutamine amidotransferase of anthranilate synthase
FYN22_04365	COG3161	chorismate lyase activity
FYN22_04370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYN22_04410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYN22_04420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYN22_04425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYN22_04440	COG1115	amino acid carrier protein
FYN22_04445	COG1113	amino acid transport
FYN22_04455	COG0019	diaminopimelate decarboxylase activity
FYN22_04465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYN22_04495	COG1522	sequence-specific DNA binding
FYN22_04500	COG1280	lysine exporter protein (LysE YggA)
FYN22_04535	COG0842	Transport permease protein
FYN22_04540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_04555	COG2175	clavaminate synthase activity
FYN22_04570	COG0024	Methionine aminopeptidase
FYN22_04575	COG0052	Belongs to the universal ribosomal protein uS2 family
FYN22_04610	COG2951	lytic endotransglycosylase activity
FYN22_04625	COG0842	Transport permease protein
FYN22_04630	COG1131	(ABC) transporter
FYN22_04640	COG0303	'Molybdopterin
FYN22_04645	COG0315	cyclic pyranopterin monophosphate synthase activity
FYN22_04645	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYN22_04650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYN22_04655	COG0243	molybdopterin cofactor binding
FYN22_04660	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FYN22_04670	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYN22_04675	COG4149	molybdate abc transporter
FYN22_04715	COG0235	Class ii aldolase
FYN22_04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_04725	COG0697	spore germination
FYN22_04730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYN22_04730	COG0475	glutathione-regulated potassium exporter activity
FYN22_04735	COG3706	GGDEF domain
FYN22_04780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYN22_04805	COG3634	alkyl hydroperoxide reductase activity
FYN22_04810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYN22_04830	COG3501	Rhs element vgr protein
FYN22_04870	COG1720	tRNA m6t6A37 methyltransferase activity
FYN22_04880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FYN22_04890	COG0745	RESPONSE REGULATOR receiver
FYN22_04895	COG0642	Histidine kinase
FYN22_04905	COG0494	nUDIX hydrolase
FYN22_04915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYN22_04920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYN22_04925	COG3139	Protein of unknown function (DUF1315)
FYN22_04940	COG1301	dicarboxylic acid transport
FYN22_04945	COG1960	acyl-CoA dehydrogenase activity
FYN22_04950	COG0693	protein deglycase activity
FYN22_04960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYN22_04965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYN22_04995	COG0415	Belongs to the DNA photolyase family
FYN22_05005	COG2252	PERMEase
FYN22_05010	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYN22_05020	COG3038	cytochrome b561
FYN22_05035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYN22_05045	COG0527	aspartate kinase activity
FYN22_05055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYN22_05070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYN22_05075	COG1522	sequence-specific DNA binding
FYN22_05090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYN22_05110	COG0667	Aldo Keto reductase
FYN22_05120	COG1765	OsmC-like protein
FYN22_05145	COG0540	Belongs to the ATCase OTCase family
FYN22_05165	COG2031	fatty acid transporter
FYN22_05170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_05195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYN22_05200	COG1960	acyl-CoA dehydrogenase activity
FYN22_05205	COG1309	transcriptional regulator
FYN22_05210	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_05240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYN22_05250	COG0659	secondary active sulfate transmembrane transporter activity
FYN22_05255	COG0625	glutathione transferase activity
FYN22_05260	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYN22_05285	COG2363	Small membrane protein
FYN22_05300	COG1278	Cold shock
FYN22_05305	COG0513	Belongs to the DEAD box helicase family
FYN22_05315	COG0778	Nitroreductase
FYN22_05340	COG0167	dihydroorotate dehydrogenase activity
FYN22_05370	COG4783	chaperone-mediated protein folding
FYN22_05375	COG1610	YqeY-like protein
FYN22_05380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYN22_05405	COG2815	serine threonine protein kinase
FYN22_05405	COG0515	serine threonine protein kinase
FYN22_05445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_05450	COG0450	alkyl hydroperoxide reductase
FYN22_05455	COG1643	Atp-dependent helicase
FYN22_05475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_05475	COG1116	anion transmembrane transporter activity
FYN22_05485	COG2223	nitrite transmembrane transporter activity
FYN22_05490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_05495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_05500	COG0243	molybdopterin cofactor binding
FYN22_05510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYN22_05545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FYN22_05550	COG0406	alpha-ribazole phosphatase activity
FYN22_05560	COG0517	IMP dehydrogenase activity
FYN22_05560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FYN22_05565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYN22_05575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FYN22_05580	COG1137	ATPase activity
FYN22_05610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FYN22_05650	COG2011	ABC-type metal ion transport system permease component
FYN22_05655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYN22_05665	COG0151	Belongs to the GarS family
FYN22_05670	COG0138	bifunctional purine biosynthesis protein purh
FYN22_05675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FYN22_05705	COG0445	tRNA wobble uridine modification
FYN22_05720	COG2308	Evidence 4 Homologs of previously reported genes of
FYN22_05730	COG1305	Transglutaminase-like
FYN22_05745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYN22_05750	COG0305	Participates in initiation and elongation during chromosome replication
FYN22_05765	COG0360	Binds together with S18 to 16S ribosomal RNA
FYN22_05785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYN22_05790	COG1845	cytochrome c oxidase, subunit III
FYN22_05795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYN22_05800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYN22_05830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_05845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYN22_05850	COG2890	protein-(glutamine-N5) methyltransferase activity
FYN22_05860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_05890	COG1960	acyl-CoA dehydrogenase activity
FYN22_05895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_05915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FYN22_05940	COG0729	surface antigen
FYN22_05985	COG4773	Receptor
FYN22_05990	COG0786	glutamate:sodium symporter activity
FYN22_06000	COG1113	amino acid transport
FYN22_06025	COG0024	Methionine aminopeptidase
FYN22_06030	COG0583	DNA-binding transcription factor activity
FYN22_06035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_06050	COG3852	Histidine kinase
FYN22_06070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYN22_06075	COG0575	Belongs to the CDS family
FYN22_06090	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_06110	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_06135	COG2137	regulation of response to DNA damage stimulus
FYN22_06140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYN22_06145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FYN22_06150	COG1011	Hydrolase
FYN22_06165	COG1218	3'(2'),5'-bisphosphate nucleotidase
FYN22_06185	COG3385	transposase activity
FYN22_06195	COG0702	epimerase
FYN22_06200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYN22_06210	COG2267	carboxylic ester hydrolase activity
FYN22_06220	COG1902	pentaerythritol trinitrate reductase activity
FYN22_06220	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYN22_06235	COG2814	Major facilitator Superfamily
FYN22_06240	COG0656	L-ascorbic acid biosynthetic process
FYN22_06245	COG0583	DNA-binding transcription factor activity
FYN22_06265	COG0148	phosphopyruvate hydratase activity
FYN22_06280	COG0772	Belongs to the SEDS family
FYN22_06295	COG0579	oxidoreductase
FYN22_06305	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_06310	COG1309	transcriptional regulator
FYN22_06315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYN22_06330	COG4890	Cyd operon protein YbgT
FYN22_06335	COG1294	oxidase, subunit
FYN22_06350	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYN22_06360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYN22_06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYN22_06385	COG0569	domain protein
FYN22_06395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYN22_06400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYN22_06410	COG3706	GGDEF domain
FYN22_06425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYN22_06430	COG0542	response to heat
FYN22_06460	COG0372	Belongs to the citrate synthase family
FYN22_06465	COG3385	transposase activity
FYN22_06490	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_06515	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYN22_06515	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYN22_06525	COG1047	Peptidyl-prolyl cis-trans
FYN22_06530	COG1252	NADH dehydrogenase
FYN22_06535	COG1686	Belongs to the peptidase S11 family
FYN22_06545	COG2351	hydroxyisourate hydrolase activity
FYN22_06585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_06600	COG0612	Peptidase, M16
FYN22_06635	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_06680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYN22_06685	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYN22_06700	COG2353	YceI-like domain
FYN22_06705	COG0519	Catalyzes the synthesis of GMP from XMP
FYN22_06705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYN22_06715	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_06725	COG4302	ethanolamine ammonia-lyase activity
FYN22_06730	COG4303	Ethanolamine ammonia lyase large subunit
FYN22_06735	COG0531	amino acid
FYN22_06755	COG1454	alcohol dehydrogenase
FYN22_06765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_06770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYN22_06775	COG2814	Major facilitator Superfamily
FYN22_06780	COG2707	UPF0756 membrane protein
FYN22_06785	COG1187	pseudouridine synthase activity
FYN22_06805	COG0802	atpase or kinase
FYN22_06810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYN22_06820	COG1923	regulation of RNA biosynthetic process
FYN22_06825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_06835	COG3178	'Phosphotransferase
FYN22_06840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYN22_06850	COG1192	Involved in chromosome partitioning
FYN22_06855	COG1475	DNA binding
FYN22_06860	COG0811	peptide transport
FYN22_06870	COG1132	(ABC) transporter
FYN22_06875	COG1663	tetraacyldisaccharide 4'-kinase activity
FYN22_06895	COG0084	hydrolase, TatD family'
FYN22_06930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYN22_06940	COG0590	tRNA wobble adenosine to inosine editing
FYN22_06960	COG0776	regulation of translation
FYN22_06975	COG2431	L-lysine efflux transmembrane transporter activity
FYN22_06990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYN22_06995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYN22_07015	COG1253	flavin adenine dinucleotide binding
FYN22_07040	COG0308	aminopeptidase N
FYN22_07050	COG0589	response to stress
FYN22_07065	COG2076	Multidrug Resistance protein
FYN22_07070	COG1309	transcriptional regulator
FYN22_07075	COG3135	benzoate transporter
FYN22_07085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYN22_07090	COG0583	DNA-binding transcription factor activity
FYN22_07105	COG0183	Belongs to the thiolase family
FYN22_07110	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_07135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYN22_07140	COG0824	Thioesterase
FYN22_07145	COG1454	alcohol dehydrogenase
FYN22_07150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYN22_07170	COG0069	glutamate synthase activity
FYN22_07175	COG2197	response regulator
FYN22_07185	COG2850	peptidyl-arginine hydroxylation
FYN22_07195	COG0424	maF-like protein
FYN22_07205	COG0126	phosphoglycerate kinase activity
FYN22_07220	COG0697	spore germination
FYN22_07240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_07250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_07255	COG3781	membrane
FYN22_07300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYN22_07315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYN22_07345	COG0316	Belongs to the HesB IscA family
FYN22_07350	COG0822	iron-sulfur transferase activity
FYN22_07360	COG1959	2 iron, 2 sulfur cluster binding
FYN22_07375	COG0776	regulation of translation
FYN22_07380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYN22_07410	COG0537	adenosine 5'-monophosphoramidase activity
FYN22_07445	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYN22_07450	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FYN22_07465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYN22_07475	COG0133	tryptophan synthase activity
FYN22_07480	COG0516	GMP reductase activity
FYN22_07480	COG0517	IMP dehydrogenase activity
FYN22_07510	COG0612	Peptidase, M16
FYN22_07515	COG0552	protein localization to endoplasmic reticulum
FYN22_07565	COG1960	acyl-CoA dehydrogenase activity
FYN22_07570	COG1960	acyl-CoA dehydrogenase activity
FYN22_07615	COG2199	diguanylate cyclase activity
FYN22_07625	COG2814	Major facilitator Superfamily
FYN22_07650	COG0864	Transcriptional regulator
FYN22_07720	COG0596	Alpha beta hydrolase
FYN22_07825	COG4628	conserved protein (DUF2132)
FYN22_07830	COG1063	alcohol dehydrogenase
FYN22_07840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_07845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYN22_07850	COG0022	dehydrogenase e1 component
FYN22_07855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FYN22_07860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYN22_07945	COG2814	Major facilitator Superfamily
FYN22_07950	COG0583	DNA-binding transcription factor activity
FYN22_07955	COG4948	Mandelate Racemase Muconate Lactonizing
FYN22_07960	COG4829	muconolactone delta-isomerase
FYN22_07970	COG4638	Rieske (2fe-2S)
FYN22_07975	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FYN22_07980	COG0543	2 iron, 2 sulfur cluster binding
FYN22_07980	COG0633	Ferredoxin
FYN22_07985	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_07990	COG3135	benzoate transporter
FYN22_07995	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYN22_08000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_08005	COG0183	Belongs to the thiolase family
FYN22_08010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_08020	COG0511	ligase activity, forming carbon-carbon bonds
FYN22_08035	COG0439	Biotin carboxylase
FYN22_08050	COG0583	DNA-binding transcription factor activity
FYN22_08055	COG0183	Belongs to the thiolase family
FYN22_08065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYN22_08075	COG2233	PERMEase
FYN22_08080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYN22_08085	COG0251	oxidation-reduction process
FYN22_08090	COG1335	isochorismatase
FYN22_08095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_08100	COG0596	Alpha beta hydrolase
FYN22_08105	COG0640	Transcriptional regulator
FYN22_08125	COG3122	Protein conserved in bacteria
FYN22_08130	COG0668	transmembrane transport
FYN22_08140	COG1132	(ABC) transporter
FYN22_08155	COG2814	Major facilitator Superfamily
FYN22_08165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYN22_08170	COG3300	MHYT domain
FYN22_08170	COG5001	Diguanylate cyclase
FYN22_08185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYN22_08190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYN22_08210	COG3123	guanosine phosphorylase activity
FYN22_08260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYN22_08265	COG2755	lipolytic protein G-D-S-L family
FYN22_08265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FYN22_08380	COG4695	Portal protein
FYN22_08470	COG4197	protein conserved in bacteria, prophage-related
FYN22_08565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYN22_08570	COG0583	DNA-binding transcription factor activity
FYN22_08575	COG1380	Effector of murein hydrolase LrgA
FYN22_08580	COG1346	cytolysis
FYN22_08595	COG2223	nitrite transmembrane transporter activity
FYN22_08625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYN22_08630	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYN22_08635	COG2207	Transcriptional regulator
FYN22_08640	COG1944	ATP diphosphatase activity
FYN22_08645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYN22_08670	COG0730	response to heat
FYN22_08675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYN22_08730	COG2072	flavoprotein involved in K transport
FYN22_08740	COG2144	transferase activity, transferring acyl groups
FYN22_08765	COG3604	Transcriptional regulator
FYN22_08785	COG2814	Major facilitator Superfamily
FYN22_08820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYN22_08825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_08845	COG3188	usher protein
FYN22_08850	COG3121	Chaperone
FYN22_08885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_08895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYN22_08900	COG1113	amino acid transport
FYN22_08905	COG0697	spore germination
FYN22_08920	COG1064	alcohol dehydrogenase
FYN22_08940	COG3293	Transposase
FYN22_08950	COG0204	Acyl-transferase
FYN22_08990	COG1464	Belongs to the NlpA lipoprotein family
FYN22_08995	COG1464	Belongs to the NlpA lipoprotein family
FYN22_09000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYN22_09005	COG2011	ABC-type metal ion transport system permease component
FYN22_09010	COG0012	GTP binding
FYN22_09035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYN22_09050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYN22_09075	COG0386	Belongs to the glutathione peroxidase family
FYN22_09080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_09085	COG0436	Aminotransferase
FYN22_09105	COG3634	alkyl hydroperoxide reductase activity
FYN22_09130	COG2070	2-Nitropropane dioxygenase
FYN22_09140	COG3038	cytochrome b561
FYN22_09170	COG1278	Cold shock
FYN22_09180	COG0604	alcohol dehydrogenase
FYN22_09185	COG1733	regulation of RNA biosynthetic process
FYN22_09260	COG1309	transcriptional regulator
FYN22_09285	COG0842	Transport permease protein
FYN22_09290	COG0842	Transport permease protein
FYN22_09295	COG1131	(ABC) transporter
FYN22_09330	COG1538	Outer membrane efflux protein
FYN22_09390	COG0714	Associated with various cellular activities
FYN22_09395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FYN22_09400	COG2879	small protein
FYN22_09405	COG1966	Carbon starvation protein
FYN22_09410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYN22_09430	COG0254	rRNA binding
FYN22_09450	COG1067	ATP-dependent peptidase activity
FYN22_09455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYN22_09460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYN22_09465	COG0616	signal peptide processing
FYN22_09470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYN22_09480	COG0573	inorganic phosphate transmembrane transporter activity
FYN22_09485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FYN22_09490	COG0076	glutamate decarboxylase activity
FYN22_09495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYN22_09505	COG4772	TonB-dependent receptor
FYN22_09510	COG0671	phosphoesterase, PA-phosphatase related
FYN22_09515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYN22_09525	COG1733	regulation of RNA biosynthetic process
FYN22_09530	COG0702	epimerase
FYN22_09560	COG0556	nucleotide-excision repair
FYN22_09625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYN22_09630	COG1381	Involved in DNA repair and RecF pathway recombination
FYN22_09640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYN22_09655	COG0681	Belongs to the peptidase S26 family
FYN22_09685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_09795	COG4387	Mu-like prophage protein GP36
FYN22_09830	COG4383	Mu-like prophage protein gp29
FYN22_10005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYN22_10025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYN22_10035	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYN22_10050	COG4208	sulfate ABC transporter
FYN22_10055	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYN22_10060	COG0583	DNA-binding transcription factor activity
FYN22_10080	COG0602	queuosine metabolic process
FYN22_10085	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYN22_10100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYN22_10110	COG0583	DNA-binding transcription factor activity
FYN22_10115	COG2353	YceI-like domain
FYN22_10120	COG1056	cytidyltransferase-related domain
FYN22_10120	COG1051	belongs to the nudix hydrolase family
FYN22_10125	COG1024	Enoyl-CoA hydratase
FYN22_10140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYN22_10140	COG3323	Protein of unknown function (DUF1653)
FYN22_10150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYN22_10150	COG0047	phosphoribosylformylglycinamidine synthase activity
FYN22_10170	COG2255	four-way junction helicase activity
FYN22_10185	COG0824	Thioesterase
FYN22_10205	COG0823	Involved in the tonB-independent uptake of proteins
FYN22_10225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYN22_10265	COG0628	permease
FYN22_10270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYN22_10275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FYN22_10295	COG2333	competence protein COMEC
FYN22_10295	COG0658	competence protein
FYN22_10300	COG1136	(ABC) transporter
FYN22_10305	COG4591	ABC-type transport system involved in lipoprotein release permease component
FYN22_10315	COG0697	spore germination
FYN22_10320	COG1671	Belongs to the UPF0178 family
FYN22_10330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_10335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYN22_10340	COG1960	acyl-CoA dehydrogenase activity
FYN22_10380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FYN22_10385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYN22_10390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYN22_10395	COG1716	ATPase activity
FYN22_10395	COG5001	Diguanylate cyclase
FYN22_10400	COG0280	phosphate acetyltransferase
FYN22_10400	COG0281	malic enzyme
FYN22_10430	COG1024	Enoyl-CoA hydratase
FYN22_10435	COG1960	acyl-CoA dehydrogenase activity
FYN22_10440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYN22_10470	COG1902	pentaerythritol trinitrate reductase activity
FYN22_10470	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYN22_10475	COG0277	FAD linked oxidase domain protein
FYN22_10485	COG2186	Transcriptional regulator
FYN22_10500	COG3706	GGDEF domain
FYN22_10500	COG4251	negative regulation of phosphorylation
FYN22_10500	COG5001	Diguanylate cyclase
FYN22_10500	COG2203	Gaf domain
FYN22_10505	COG0418	dihydroorotase activity
FYN22_10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYN22_10520	COG0833	amino acid
FYN22_10535	COG0833	amino acid
FYN22_10555	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FYN22_10570	COG4172	Belongs to the ABC transporter superfamily
FYN22_10575	COG4239	(ABC) transporter, permease
FYN22_10580	COG4174	ABC transporter (Permease)
FYN22_10585	COG4166	transmembrane transport
FYN22_10590	COG0741	lytic transglycosylase activity
FYN22_10590	COG1388	LysM domain
FYN22_10595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYN22_10630	COG0583	DNA-binding transcription factor activity
FYN22_10635	COG1388	LysM domain
FYN22_10635	COG4942	peptidase
FYN22_10650	COG0753	catalase activity
FYN22_10680	COG1686	Belongs to the peptidase S11 family
FYN22_10685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FYN22_10705	COG2915	High frequency lysogenization protein hflD homolog
FYN22_10725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYN22_10730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYN22_10750	COG0006	proline dipeptidase activity
FYN22_10805	COG3706	GGDEF domain
FYN22_10820	COG1785	Belongs to the alkaline phosphatase family
FYN22_10825	COG1785	Belongs to the alkaline phosphatase family
FYN22_10845	COG4770	biotin carboxylase activity
FYN22_10865	COG1914	H( )-stimulated, divalent metal cation uptake system
FYN22_10870	COG0583	DNA-binding transcription factor activity
FYN22_10875	COG2217	Heavy metal translocating P-type atpase
FYN22_10885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYN22_10900	COG2234	aminopeptidase activity
FYN22_10910	COG3384	dioxygenase
FYN22_10920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYN22_10925	COG2878	Part of a membrane complex involved in electron transport
FYN22_10930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYN22_10955	COG0768	penicillin binding
FYN22_10960	COG0742	ribosomal rna small subunit methyltransferase
FYN22_10975	COG0204	Acyl-transferase
FYN22_10990	COG3119	arylsulfatase activity
FYN22_11035	COG0477	Major facilitator Superfamily
FYN22_11090	COG1695	Transcriptional regulator
FYN22_11110	COG0175	sulfate reduction
FYN22_11135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYN22_11140	COG1773	rubredoxin
FYN22_11145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_11155	COG0583	DNA-binding transcription factor activity
FYN22_11175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYN22_11180	COG4181	ATPase activity
FYN22_11205	COG4771	TonB-dependent receptor
FYN22_11225	COG0306	phosphate transporter
FYN22_11240	COG2852	Protein conserved in bacteria
FYN22_11255	COG2223	nitrite transmembrane transporter activity
FYN22_11260	COG2207	Transcriptional regulator
FYN22_11265	COG0242	peptide deformylase activity
FYN22_11270	COG0477	Major facilitator Superfamily
FYN22_11315	COG2203	Gaf domain
FYN22_11315	COG2199	diguanylate cyclase activity
FYN22_11325	COG4681	YaeQ
FYN22_11330	COG0523	cobalamin synthesis protein
FYN22_11340	COG1607	acyl-coa hydrolase
FYN22_11345	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYN22_11355	COG1115	amino acid carrier protein
FYN22_11360	COG0786	glutamate:sodium symporter activity
FYN22_11375	COG2814	Major facilitator Superfamily
FYN22_11380	COG1289	transmembrane transporter activity
FYN22_11390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FYN22_11460	COG2832	Protein of unknown function (DUF454)
FYN22_11470	COG5510	response to toxic substance
FYN22_11475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYN22_11485	COG2198	Histidine kinase
FYN22_11485	COG0643	Histidine kinase
FYN22_11485	COG2198	Histidine kinase
FYN22_11485	COG0643	Histidine kinase
FYN22_11490	COG0840	transmembrane signaling receptor activity
FYN22_11575	COG0489	protein tyrosine kinase activity
FYN22_11600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_11600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_11635	COG4716	Myosin-crossreactive antigen
FYN22_11665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FYN22_11670	COG2081	HI0933 family
FYN22_11680	COG0668	transmembrane transport
FYN22_11700	COG0765	amino acid transport
FYN22_11705	COG0765	amino acid transport
FYN22_11710	COG1126	abc transporter atp-binding protein
FYN22_11720	COG0004	ammonium transporteR
FYN22_11735	COG0642	Histidine kinase
FYN22_11740	COG0745	RESPONSE REGULATOR receiver
FYN22_11765	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYN22_11780	COG0142	geranyltranstransferase activity
FYN22_11785	COG2828	Protein conserved in bacteria
FYN22_11790	COG1113	amino acid transport
FYN22_11805	COG1113	amino acid transport
FYN22_11825	COG0625	glutathione transferase activity
FYN22_11840	COG0431	NADPH-dependent FMN reductase
FYN22_11845	COG0798	PFAM Bile acid sodium symporter
FYN22_11855	COG0640	Transcriptional regulator
FYN22_11905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYN22_11910	COG1530	ribonuclease E activity
FYN22_11915	COG0424	maF-like protein
FYN22_11920	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FYN22_11925	COG1792	Involved in formation and maintenance of cell shape
FYN22_11930	COG1077	Cell shape determining protein MreB Mrl
FYN22_11935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYN22_11945	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYN22_11980	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FYN22_11990	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_11995	COG2610	gluconate transmembrane transporter activity
FYN22_12000	COG0583	DNA-binding transcription factor activity
FYN22_12010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_12020	COG4772	TonB-dependent receptor
FYN22_12025	COG4993	Dehydrogenase
FYN22_12030	COG3659	wide pore channel activity
FYN22_12035	COG3420	alginic acid biosynthetic process
FYN22_12040	COG0710	3-dehydroquinate dehydratase activity
FYN22_12045	COG3485	protocatechuate 3,4-dioxygenase
FYN22_12050	COG3485	protocatechuate 3,4-dioxygenase
FYN22_12055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYN22_12060	COG2271	Major facilitator Superfamily
FYN22_12065	COG0596	Alpha beta hydrolase
FYN22_12070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYN22_12075	COG0183	Belongs to the thiolase family
FYN22_12080	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYN22_12085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYN22_12090	COG1414	Transcriptional regulator
FYN22_12120	COG1113	amino acid transport
FYN22_12130	COG3724	N-succinylarginine dihydrolase activity
FYN22_12135	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_12140	COG3138	arginine N-succinyltransferase
FYN22_12150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYN22_12155	COG1522	sequence-specific DNA binding
FYN22_12175	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_12180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYN22_12205	COG1271	oxidase subunit
FYN22_12210	COG1294	oxidase, subunit
FYN22_12220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYN22_12230	COG1346	cytolysis
FYN22_12240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYN22_12250	COG1522	sequence-specific DNA binding
FYN22_12275	COG2963	transposase activity
FYN22_12285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYN22_12305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYN22_12310	COG0583	DNA-binding transcription factor activity
FYN22_12315	COG4221	oxidoreductase activity
FYN22_12345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYN22_12380	COG0642	Histidine kinase
FYN22_12395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYN22_12420	COG2816	NAD+ diphosphatase activity
FYN22_12425	COG3046	protein related to deoxyribodipyrimidine photolyase
FYN22_12470	COG3177	Filamentation induced by cAMP protein fic
FYN22_12475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FYN22_12535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FYN22_12600	COG0582	viral genome integration into host DNA
FYN22_12610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYN22_12615	COG2814	Major facilitator Superfamily
FYN22_12620	COG1566	PFAM secretion protein HlyD family protein
FYN22_12625	COG2050	protein possibly involved in aromatic compounds catabolism
FYN22_12640	COG1090	epimerase
FYN22_12650	COG4251	negative regulation of phosphorylation
FYN22_12650	COG3706	GGDEF domain
FYN22_12650	COG5001	Diguanylate cyclase
FYN22_12650	COG2203	Gaf domain
FYN22_12655	COG0420	3'-5' exonuclease activity
FYN22_12685	COG0735	belongs to the Fur family
FYN22_12690	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYN22_12695	COG2914	Belongs to the UPF0125 (RnfH) family
FYN22_12710	COG0121	glutamine amidotransferase
FYN22_12725	COG0756	dUTP diphosphatase activity
FYN22_12730	COG0210	DNA helicase
FYN22_12735	COG2885	chlorophyll binding
FYN22_12740	COG0204	Acyl-transferase
FYN22_12750	COG0850	regulation of cytokinetic process
FYN22_12755	COG2894	cell division
FYN22_12760	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYN22_12775	COG0531	amino acid
FYN22_12775	COG1674	ftsk spoiiie
FYN22_12780	COG0492	ferredoxin-NADP+ reductase activity
FYN22_12785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYN22_12795	COG0456	acetyltransferase
FYN22_12840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYN22_12865	COG1113	amino acid transport
FYN22_12870	COG0251	oxidation-reduction process
FYN22_12885	COG1522	sequence-specific DNA binding
FYN22_12900	COG0352	thiamine-phosphate diphosphorylase activity
FYN22_12900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYN22_12900	COG0351	phosphomethylpyrimidine kinase
FYN22_12910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYN22_12915	COG2076	Multidrug Resistance protein
FYN22_12920	COG2076	Multidrug Resistance protein
FYN22_12935	COG2132	Multicopper oxidase
FYN22_12945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYN22_12980	COG1968	undecaprenyl-diphosphatase activity
FYN22_12985	COG1214	PFAM Peptidase M22, glycoprotease
FYN22_12990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FYN22_12995	COG0494	nUDIX hydrolase
FYN22_13045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYN22_13055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYN22_13080	COG0693	protein deglycase activity
FYN22_13100	COG2814	Major facilitator Superfamily
FYN22_13130	COG2853	Lipoprotein
FYN22_13135	COG2208	phosphoserine phosphatase activity
FYN22_13145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYN22_13150	COG1764	response to oxidative stress
FYN22_13180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYN22_13180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYN22_13195	COG0037	tRNA processing
FYN22_13230	COG0072	phenylalanine-tRNA ligase activity
FYN22_13255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYN22_13275	COG1238	metal cluster binding
FYN22_13285	COG0625	glutathione transferase activity
FYN22_13305	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_13310	COG3028	Belongs to the UPF0307 family
FYN22_13320	COG1660	Displays ATPase and GTPase activities
FYN22_13325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYN22_13335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FYN22_13340	COG0617	tRNA 3'-terminal CCA addition
FYN22_13345	COG1555	photosystem II stabilization
FYN22_13350	COG3956	TIGRFAM MazG family protein
FYN22_13360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYN22_13375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYN22_13380	COG2205	protein histidine kinase activity
FYN22_13380	COG5002	protein histidine kinase activity
FYN22_13380	COG0784	Response regulator, receiver
FYN22_13385	COG1024	Enoyl-CoA hydratase
FYN22_13390	COG2084	Dehydrogenase
FYN22_13395	COG3622	Belongs to the hyi family
FYN22_13410	COG0004	ammonium transporteR
FYN22_13420	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FYN22_13425	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FYN22_13430	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FYN22_13440	COG2814	Major facilitator Superfamily
FYN22_13455	COG2072	flavoprotein involved in K transport
FYN22_13460	COG0492	ferredoxin-NADP+ reductase activity
FYN22_13465	COG0431	NADPH-dependent FMN reductase
FYN22_13470	COG0798	PFAM Bile acid sodium symporter
FYN22_13480	COG0640	Transcriptional regulator
FYN22_13560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYN22_13580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYN22_13635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYN22_13645	COG0084	hydrolase, TatD family'
FYN22_13660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYN22_13670	COG0793	Belongs to the peptidase S41A family
FYN22_13690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYN22_13695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYN22_13700	COG0280	phosphate acetyltransferase
FYN22_13700	COG0857	belongs to the CobB CobQ family
FYN22_13725	COG3708	Transcriptional regulator
FYN22_13725	COG2207	Transcriptional regulator
FYN22_13735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FYN22_13735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FYN22_13755	COG0740	serine-type endopeptidase activity
FYN22_13765	COG4771	TonB-dependent receptor
FYN22_13770	COG4774	siderophore transport
FYN22_13785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYN22_13795	COG2813	Specifically methylates the guanine in position
FYN22_13795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYN22_13905	COG0788	formyltetrahydrofolate deformylase activity
FYN22_13920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYN22_13925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYN22_13930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYN22_13930	COG4651	solute:proton antiporter activity
FYN22_13955	COG0210	DNA helicase
FYN22_13960	COG1929	Belongs to the glycerate kinase type-1 family
FYN22_14000	COG2900	Belongs to the SlyX family
FYN22_14015	COG1560	Kdo2-lipid A biosynthetic process
FYN22_14060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYN22_14075	COG0473	3-isopropylmalate dehydrogenase activity
FYN22_14090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYN22_14100	COG0583	DNA-binding transcription factor activity
FYN22_14135	COG1280	lysine exporter protein (LysE YggA)
FYN22_14150	COG1960	acyl-CoA dehydrogenase activity
FYN22_14160	COG3293	Transposase
FYN22_14185	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYN22_14200	COG0583	DNA-binding transcription factor activity
FYN22_14215	COG0564	pseudouridine synthase activity
FYN22_14225	COG1530	ribonuclease E activity
FYN22_14230	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_14255	COG1983	PspC domain protein
FYN22_14275	COG0751	glycine-tRNA ligase activity
FYN22_14310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYN22_14325	COG2226	methyltransferase
FYN22_14350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FYN22_14360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYN22_14365	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYN22_14375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FYN22_14385	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FYN22_14385	COG0644	oxidoreductase
FYN22_14395	COG0425	Belongs to the sulfur carrier protein TusA family
FYN22_14400	COG4535	Mg2 and Co2 transporter CorC
FYN22_14405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYN22_14410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYN22_14430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYN22_14440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYN22_14460	COG2841	Protein conserved in bacteria
FYN22_14465	COG0598	Magnesium transport protein CorA
FYN22_14470	COG1185	polyribonucleotide nucleotidyltransferase activity
FYN22_14485	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_14490	COG1074	ATP-dependent DNA helicase activity
FYN22_14495	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FYN22_14525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYN22_14540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYN22_14550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FYN22_14555	COG2111	Na H antiporter
FYN22_14555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYN22_14560	COG1006	Multisubunit Na H antiporter MnhC subunit
FYN22_14565	COG0651	ATP synthesis coupled electron transport
FYN22_14575	COG2212	antiporter activity
FYN22_14585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYN22_14595	COG0195	Participates in both transcription termination and antitermination
FYN22_14655	COG0237	dephospho-CoA kinase activity
FYN22_14665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYN22_14670	COG3123	guanosine phosphorylase activity
FYN22_14675	COG0497	DNA recombination
FYN22_14680	COG1678	Uncharacterized ACR, COG1678
FYN22_14685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYN22_14700	COG1289	transmembrane transporter activity
FYN22_14715	COG1132	(ABC) transporter
FYN22_14720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYN22_14790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FYN22_14815	COG0326	Molecular chaperone. Has ATPase activity
FYN22_14825	COG3047	cAMP biosynthetic process
FYN22_14830	COG2056	Na+-H+ antiporter family
FYN22_14855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYN22_14860	COG0085	RNA polymerase activity
FYN22_14865	COG0222	ribosome binding
FYN22_14870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYN22_14875	COG0081	regulation of translation
FYN22_14880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYN22_14930	COG0546	phosphoglycolate phosphatase activity
FYN22_14965	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_14995	COG1324	tolerance protein
FYN22_15000	COG0673	inositol 2-dehydrogenase activity
FYN22_15020	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_15025	COG0824	Thioesterase
FYN22_15045	COG0181	hydroxymethylbilane synthase activity
FYN22_15055	COG3275	phosphorelay sensor kinase activity
FYN22_15075	COG1538	Outer membrane efflux protein
FYN22_15085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYN22_15095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYN22_15100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FYN22_15105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYN22_15110	COG0772	Belongs to the SEDS family
FYN22_15115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYN22_15135	COG4974	Belongs to the 'phage' integrase family
FYN22_15140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYN22_15150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FYN22_15155	COG1686	Belongs to the peptidase S11 family
FYN22_15160	COG2197	response regulator
FYN22_15175	COG0793	Belongs to the peptidase S41A family
FYN22_15180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FYN22_15185	COG0795	lipopolysaccharide-transporting ATPase activity
FYN22_15190	COG0795	lipopolysaccharide-transporting ATPase activity
FYN22_15210	COG0586	Pfam SNARE associated Golgi protein
FYN22_15225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYN22_15225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYN22_15235	COG0004	ammonium transporteR
FYN22_15240	COG0347	Belongs to the P(II) protein family
FYN22_15250	COG0606	chelatase, subunit chli
FYN22_15270	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FYN22_15285	COG0318	PFAM AMP-dependent synthetase and ligase
FYN22_15295	COG0477	Major facilitator Superfamily
FYN22_15300	COG2860	membrane
FYN22_15305	COG3012	SEC-C Motif Domain Protein
FYN22_15310	COG1253	flavin adenine dinucleotide binding
FYN22_15330	COG2814	Major facilitator Superfamily
FYN22_15340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_15420	COG0758	DNA mediated transformation
FYN22_15430	COG0697	spore germination
FYN22_15440	COG0386	Belongs to the glutathione peroxidase family
FYN22_15475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYN22_15485	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYN22_15525	COG1121	(ABC) transporter
FYN22_15530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYN22_15545	COG2837	iron assimilation
FYN22_15555	COG1388	LysM domain
FYN22_15555	COG3409	Peptidoglycan-binding domain 1 protein
FYN22_15555	COG5632	N-Acetylmuramoyl-L-alanine amidase
FYN22_15560	COG3501	Rhs element vgr protein
FYN22_15565	COG0281	malic enzyme
FYN22_15615	COG0519	Catalyzes the synthesis of GMP from XMP
FYN22_15615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYN22_15630	COG0586	Pfam SNARE associated Golgi protein
FYN22_15645	COG1192	Involved in chromosome partitioning
FYN22_15655	COG0271	Belongs to the BolA IbaG family
FYN22_15750	COG1538	Outer membrane efflux protein
FYN22_15950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYN22_15955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FYN22_15955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYN22_15955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYN22_15960	COG1105	Belongs to the carbohydrate kinase PfkB family
FYN22_15965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYN22_15965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYN22_15970	COG0583	DNA-binding transcription factor activity
FYN22_15975	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYN22_15990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYN22_16000	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FYN22_16005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYN22_16015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYN22_16020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYN22_16025	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYN22_16040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FYN22_16055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYN22_16070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FYN22_16080	COG1086	Polysaccharide biosynthesis protein
FYN22_16095	COG0438	transferase activity, transferring glycosyl groups
FYN22_16105	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYN22_16115	COG1596	polysaccharide export
FYN22_16140	COG0728	peptidoglycan biosynthetic process
FYN22_16145	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYN22_16155	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYN22_16165	COG3307	-O-antigen
FYN22_16170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYN22_16175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYN22_16180	COG0546	phosphoglycolate phosphatase activity
FYN22_16185	COG1028	Short-chain dehydrogenase reductase Sdr
FYN22_16205	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYN22_16205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYN22_16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_16215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYN22_16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYN22_16225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYN22_16230	COG1116	anion transmembrane transporter activity
FYN22_16235	COG1309	transcriptional regulator
FYN22_16250	COG0196	riboflavin kinase activity
FYN22_16255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYN22_16260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYN22_16265	COG1047	Peptidyl-prolyl cis-trans
FYN22_16280	COG2133	pyrroloquinoline quinone binding
FYN22_16310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYN22_16315	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYN22_16320	COG2951	lytic endotransglycosylase activity
FYN22_16325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYN22_16340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYN22_16360	COG0861	Integral membrane protein TerC family
FYN22_16370	COG0754	glutathionylspermidine amidase activity
FYN22_16380	COG0402	S-adenosylhomocysteine deaminase activity
FYN22_16395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYN22_16400	COG1230	cation diffusion facilitator family transporter
FYN22_16410	COG2814	Major facilitator Superfamily
FYN22_16420	COG0706	membrane insertase activity
FYN22_16425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYN22_16435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYN22_16535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYN22_16560	COG0789	Transcriptional regulator
FYN22_16620	COG3316	Transposase and inactivated derivatives
FYN22_16635	COG0210	DNA helicase
FYN22_16655	COG0583	DNA-binding transcription factor activity
FYN22_16660	COG2814	Major facilitator Superfamily
FYN22_16690	COG1012	belongs to the aldehyde dehydrogenase family
FYN22_16705	COG3316	Transposase and inactivated derivatives
FYN22_16715	COG3316	Transposase and inactivated derivatives
FYN22_16730	COG1538	Outer membrane efflux protein
FYN22_16735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYN22_16745	COG0745	RESPONSE REGULATOR receiver
FYN22_16750	COG2205	protein histidine kinase activity
FYN22_16765	COG3173	Aminoglycoside phosphotransferase
FYN22_16790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYN22_16795	COG3657	addiction module killer protein
FYN22_16865	COG3316	Transposase and inactivated derivatives
FYN22_16890	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYN22_16910	COG4372	Transposase
FYN22_16995	COG4783	chaperone-mediated protein folding
FYN22_17215	COG1538	Outer membrane efflux protein
FYN22_17225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYN22_17230	COG1230	cation diffusion facilitator family transporter
FYN22_17240	COG0640	Transcriptional regulator
FYN22_17250	COG0789	Transcriptional regulator
FYN22_17360	COG1192	Involved in chromosome partitioning
FYN22_17365	COG1475	DNA binding
FYN22_17545	COG2009	succinate dehydrogenase
FYN22_17565	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYN22_17575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYN22_17630	COG0625	glutathione transferase activity
FYN22_17635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_17660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYN22_17695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYN22_17760	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_17770	COG2826	transposase and inactivated derivatives, IS30 family
FYN22_17930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FYN22_17985	COG1525	nuclease
FYN22_18025	COG1917	Cupin 2, conserved barrel domain protein
FYN22_18025	COG4977	sequence-specific DNA binding
FYN22_18030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_18040	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYN22_18045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_18060	COG0183	Belongs to the thiolase family
FYN22_18065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYN22_18070	COG3706	GGDEF domain
FYN22_18135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FYN22_18155	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FYN22_18160	COG3421	Type III restriction
FYN22_18200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FYN22_18315	COG4115	mRNA cleavage
FYN22_18360	COG4115	mRNA cleavage
FYN22_18405	COG4115	mRNA cleavage