locus-tag	class	description
LXM48_00015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM48_00040	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
LXM48_00085	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_00215	COG0582	viral genome integration into host DNA
LXM48_00245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LXM48_00270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXM48_00275	COG1278	Cold shock
LXM48_00290	COG0531	amino acid
LXM48_00295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXM48_00325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXM48_00360	COG0427	acetyl-CoA hydrolase
LXM48_00390	COG4221	oxidoreductase activity
LXM48_00395	COG2873	o-acetylhomoserine
LXM48_00400	COG0488	(ABC) transporter
LXM48_00420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXM48_00435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXM48_00455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXM48_00460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXM48_00470	COG2226	methyltransferase
LXM48_00520	COG0069	glutamate synthase activity
LXM48_00520	COG0070	glutamate synthase
LXM48_00520	COG0067	glutamate synthase
LXM48_00525	COG0493	'glutamate synthase
LXM48_00535	COG1704	LemA family
LXM48_00540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LXM48_00550	COG4969	Belongs to the N-Me-Phe pilin family
LXM48_00575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXM48_00580	COG1758	RNA polymerase activity
LXM48_00585	COG0194	GDP metabolic process
LXM48_00630	COG0228	four-way junction DNA binding
LXM48_00635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXM48_00645	COG0335	large ribosomal subunit rRNA binding
LXM48_00660	COG5380	lipid catabolic process
LXM48_00665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LXM48_00685	COG5006	permease, DMT superfamily
LXM48_00690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXM48_00695	COG0277	FAD linked oxidase domain protein
LXM48_00720	COG2814	Major facilitator Superfamily
LXM48_00725	COG1289	transmembrane transporter activity
LXM48_00730	COG2032	superoxide dismutase activity
LXM48_00735	COG0628	permease
LXM48_00740	COG1192	Involved in chromosome partitioning
LXM48_00750	COG2226	methyltransferase
LXM48_00765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXM48_00770	COG0254	rRNA binding
LXM48_00775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXM48_00785	COG0534	Mate efflux family protein
LXM48_00795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXM48_00805	COG1960	acyl-CoA dehydrogenase activity
LXM48_00825	COG0408	coproporphyrinogen oxidase activity
LXM48_00830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXM48_00850	COG0513	Belongs to the DEAD box helicase family
LXM48_00855	COG1127	ABC transporter
LXM48_00860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LXM48_00865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LXM48_00870	COG2854	intermembrane phospholipid transfer
LXM48_00880	COG0598	Magnesium transport protein CorA
LXM48_00890	COG0494	nUDIX hydrolase
LXM48_00895	COG1040	competence protein
LXM48_00900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXM48_00920	COG2937	Belongs to the GPAT DAPAT family
LXM48_00925	COG1946	Acyl-CoA thioesterase
LXM48_00930	COG1301	dicarboxylic acid transport
LXM48_00945	COG1959	2 iron, 2 sulfur cluster binding
LXM48_00955	COG0433	COG0433 Predicted ATPase
LXM48_00975	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LXM48_00980	COG0088	Forms part of the polypeptide exit tunnel
LXM48_00995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LXM48_01045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LXM48_01050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LXM48_01060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LXM48_01085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LXM48_01100	COG0202	RNA polymerase activity
LXM48_01105	COG0203	ribosomal protein L17
LXM48_01110	COG2072	flavoprotein involved in K transport
LXM48_01120	COG1960	acyl-CoA dehydrogenase activity
LXM48_01125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LXM48_01155	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LXM48_01160	COG0339	signal peptide processing
LXM48_01165	COG2720	vancomycin resistance protein
LXM48_01170	COG0557	exoribonuclease II activity
LXM48_01200	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXM48_01215	COG1295	ribonuclease BN
LXM48_01260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LXM48_01265	COG1702	phosphate starvation-inducible protein PhoH
LXM48_01270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXM48_01275	COG0739	heme binding
LXM48_01275	COG1196	nuclear chromosome segregation
LXM48_01275	COG0741	lytic transglycosylase activity
LXM48_01285	COG0039	L-malate dehydrogenase activity
LXM48_01310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LXM48_01315	COG1183	phosphatidylcholine synthase activity
LXM48_01375	COG1607	acyl-coa hydrolase
LXM48_01390	COG1666	GTP binding
LXM48_01410	COG2350	Protein conserved in bacteria
LXM48_01420	COG0613	PHP domain protein
LXM48_01425	COG3781	membrane
LXM48_01435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXM48_01460	COG1162	GTPase activity
LXM48_01465	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LXM48_01480	COG1538	Outer membrane efflux protein
LXM48_01485	COG0577	efflux transmembrane transporter activity
LXM48_01485	COG1136	(ABC) transporter
LXM48_01490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM48_01515	COG0028	Belongs to the TPP enzyme family
LXM48_01520	COG0440	acetolactate synthase activity
LXM48_01550	COG0438	transferase activity, transferring glycosyl groups
LXM48_01580	COG1426	Protein conserved in bacteria
LXM48_01600	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXM48_01625	COG1862	Preprotein translocase
LXM48_01635	COG1704	LemA family
LXM48_01645	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LXM48_01655	COG5002	protein histidine kinase activity
LXM48_01660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LXM48_01710	COG4641	Protein conserved in bacteria
LXM48_01710	COG0438	transferase activity, transferring glycosyl groups
LXM48_01725	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LXM48_01755	COG3223	Belongs to the PsiE family
LXM48_01760	COG1960	acyl-CoA dehydrogenase activity
LXM48_01765	COG1960	acyl-CoA dehydrogenase activity
LXM48_01775	COG2205	protein histidine kinase activity
LXM48_01780	COG0745	RESPONSE REGULATOR receiver
LXM48_01785	COG1113	amino acid transport
LXM48_01790	COG2315	Protein conserved in bacteria
LXM48_01795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LXM48_01815	COG2096	Adenosyltransferase
LXM48_01820	COG4206	TonB-dependent receptor
LXM48_01870	COG0285	dihydrofolate synthase activity
LXM48_01890	COG0450	alkyl hydroperoxide reductase
LXM48_01910	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXM48_01915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LXM48_01945	COG2199	diguanylate cyclase activity
LXM48_01990	COG2969	positive regulation of protein catabolic process
LXM48_01995	COG0625	glutathione transferase activity
LXM48_02005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXM48_02010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LXM48_02015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LXM48_02020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXM48_02025	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LXM48_02050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXM48_02060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXM48_02065	COG1408	metallophosphoesterase
LXM48_02075	COG0477	Major facilitator Superfamily
LXM48_02080	COG1272	protein, Hemolysin III
LXM48_02100	COG1024	Enoyl-CoA hydratase
LXM48_02100	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXM48_02105	COG0183	Belongs to the thiolase family
LXM48_02110	COG2207	Transcriptional regulator
LXM48_02115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LXM48_02130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM48_02150	COG0183	Belongs to the thiolase family
LXM48_02170	COG0833	amino acid
LXM48_02175	COG2813	Specifically methylates the guanine in position
LXM48_02180	COG2233	PERMEase
LXM48_02185	COG1217	gtp-binding protein TYPA
LXM48_02190	COG1970	mechanosensitive ion channel activity
LXM48_02200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXM48_02210	COG3659	wide pore channel activity
LXM48_02215	COG1902	pentaerythritol trinitrate reductase activity
LXM48_02250	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXM48_02300	COG0346	lactoylglutathione lyase activity
LXM48_02305	COG0564	pseudouridine synthase activity
LXM48_02325	COG3189	MarR family transcriptional regulator
LXM48_02330	COG2824	Alkylphosphonate utilization operon protein PhnA
LXM48_02340	COG3422	double-strand break repair
LXM48_02360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXM48_02375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXM48_02395	COG0730	response to heat
LXM48_02405	COG1196	nuclear chromosome segregation
LXM48_02410	COG3115	cell septum assembly
LXM48_02415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXM48_02420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXM48_02425	COG4774	siderophore transport
LXM48_02445	COG2193	ferroxidase activity
LXM48_02450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXM48_02455	COG0596	Alpha beta hydrolase
LXM48_02455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM48_02455	COG2226	methyltransferase
LXM48_02470	COG4106	trans-aconitate 2-methyltransferase activity
LXM48_02500	COG4206	TonB-dependent receptor
LXM48_02540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LXM48_02545	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LXM48_02555	COG0009	L-threonylcarbamoyladenylate synthase
LXM48_02560	COG3101	peptidyl-lysine hydroxylation
LXM48_02565	COG1399	metal-binding, possibly nucleic acid-binding protein
LXM48_02580	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_02590	COG1652	LysM domain
LXM48_02595	COG1802	Transcriptional regulator
LXM48_02630	COG3209	COG3209 Rhs family protein
LXM48_02655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXM48_02670	COG0745	RESPONSE REGULATOR receiver
LXM48_02675	COG2205	protein histidine kinase activity
LXM48_02685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXM48_02705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LXM48_02720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXM48_02730	COG0713	ATP synthesis coupled electron transport
LXM48_02735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXM48_02740	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LXM48_02755	COG1278	Cold shock
LXM48_02765	COG0583	DNA-binding transcription factor activity
LXM48_02815	COG0525	valine-tRNA ligase activity
LXM48_02825	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_02840	COG0393	Putative heavy-metal-binding
LXM48_02845	COG1538	Outer membrane efflux protein
LXM48_02855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM48_02860	COG0671	phosphoesterase, PA-phosphatase related
LXM48_02880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXM48_02895	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LXM48_02905	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LXM48_02910	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXM48_02910	COG1648	precorrin-2 dehydrogenase activity
LXM48_02915	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXM48_02935	COG0531	amino acid
LXM48_02950	COG0321	lipoyl(octanoyl) transferase activity
LXM48_02955	COG2921	Belongs to the UPF0250 family
LXM48_02975	COG1280	lysine exporter protein (LysE YggA)
LXM48_02990	COG0586	Pfam SNARE associated Golgi protein
LXM48_03045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXM48_03075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LXM48_03090	COG0358	DNA primase activity
LXM48_03100	COG0564	pseudouridine synthase activity
LXM48_03125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXM48_03150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXM48_03150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXM48_03165	COG0300	oxidoreductase activity
LXM48_03170	COG2072	flavoprotein involved in K transport
LXM48_03180	COG2009	succinate dehydrogenase
LXM48_03185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LXM48_03190	COG1053	succinate dehydrogenase
LXM48_03195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LXM48_03215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXM48_03225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXM48_03235	COG2268	Band 7 protein
LXM48_03240	COG1585	Membrane protein implicated in regulation of membrane protease activity
LXM48_03250	COG2354	Protein conserved in bacteria
LXM48_03255	COG2321	neutral zinc metallopeptidase
LXM48_03270	COG3695	enzyme binding
LXM48_03300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXM48_03305	COG0505	Belongs to the CarA family
LXM48_03330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXM48_03335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXM48_03375	COG2851	Citrate transporter
LXM48_03380	COG1253	flavin adenine dinucleotide binding
LXM48_03410	COG2239	Acts as a magnesium transporter
LXM48_03425	COG0501	Belongs to the peptidase M48B family
LXM48_03430	COG0741	lytic transglycosylase activity
LXM48_03435	COG0037	tRNA processing
LXM48_03445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LXM48_03450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXM48_03480	COG1309	transcriptional regulator
LXM48_03495	COG1741	Belongs to the pirin family
LXM48_03515	COG3739	integral membrane protein
LXM48_03530	COG3706	GGDEF domain
LXM48_03540	COG0302	gtp cyclohydrolase
LXM48_03550	COG0300	oxidoreductase activity
LXM48_03570	COG0134	indole-3-glycerol-phosphate synthase activity
LXM48_03575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXM48_03580	COG0512	Glutamine amidotransferase of anthranilate synthase
LXM48_03585	COG0174	glutamine synthetase
LXM48_03595	COG3161	chorismate lyase activity
LXM48_03600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LXM48_03625	COG3550	peptidyl-serine autophosphorylation
LXM48_03655	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LXM48_03660	COG1335	isochorismatase
LXM48_03665	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXM48_03680	COG0542	response to heat
LXM48_03715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXM48_03735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LXM48_03735	COG3264	Mechanosensitive ion channel
LXM48_03780	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_03815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXM48_03820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXM48_03825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXM48_03830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXM48_03845	COG1115	amino acid carrier protein
LXM48_03850	COG1113	amino acid transport
LXM48_03860	COG0019	diaminopimelate decarboxylase activity
LXM48_03870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LXM48_03885	COG1522	sequence-specific DNA binding
LXM48_03890	COG1280	lysine exporter protein (LysE YggA)
LXM48_03925	COG0842	Transport permease protein
LXM48_03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM48_03945	COG2175	clavaminate synthase activity
LXM48_03965	COG0052	Belongs to the universal ribosomal protein uS2 family
LXM48_04000	COG2951	lytic endotransglycosylase activity
LXM48_04015	COG0842	Transport permease protein
LXM48_04020	COG1131	(ABC) transporter
LXM48_04030	COG0582	viral genome integration into host DNA
LXM48_04105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXM48_04125	COG0303	'Molybdopterin
LXM48_04130	COG0315	cyclic pyranopterin monophosphate synthase activity
LXM48_04130	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXM48_04135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXM48_04140	COG0243	molybdopterin cofactor binding
LXM48_04145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXM48_04155	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXM48_04160	COG4149	molybdate abc transporter
LXM48_04165	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LXM48_04200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXM48_04220	COG3634	alkyl hydroperoxide reductase activity
LXM48_04225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXM48_04230	COG0826	peptidase U32
LXM48_04290	COG1720	tRNA m6t6A37 methyltransferase activity
LXM48_04305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXM48_04320	COG0642	Histidine kinase
LXM48_04330	COG0494	nUDIX hydrolase
LXM48_04340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXM48_04345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXM48_04350	COG3139	Protein of unknown function (DUF1315)
LXM48_04365	COG1301	dicarboxylic acid transport
LXM48_04370	COG1960	acyl-CoA dehydrogenase activity
LXM48_04375	COG0693	protein deglycase activity
LXM48_04385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXM48_04390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LXM48_04420	COG0415	Belongs to the DNA photolyase family
LXM48_04430	COG2252	PERMEase
LXM48_04435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LXM48_04445	COG3038	cytochrome b561
LXM48_04460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXM48_04470	COG0527	aspartate kinase activity
LXM48_04475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXM48_04480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXM48_04495	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXM48_04500	COG1522	sequence-specific DNA binding
LXM48_04515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXM48_04530	COG0667	Aldo Keto reductase
LXM48_04540	COG1765	OsmC-like protein
LXM48_04565	COG0540	Belongs to the ATCase OTCase family
LXM48_04585	COG2031	fatty acid transporter
LXM48_04590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM48_04605	COG4770	biotin carboxylase activity
LXM48_04615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXM48_04620	COG1960	acyl-CoA dehydrogenase activity
LXM48_04625	COG1309	transcriptional regulator
LXM48_04630	COG0318	PFAM AMP-dependent synthetase and ligase
LXM48_04660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXM48_04670	COG0659	secondary active sulfate transmembrane transporter activity
LXM48_04675	COG0625	glutathione transferase activity
LXM48_04680	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXM48_04705	COG2363	Small membrane protein
LXM48_04720	COG1278	Cold shock
LXM48_04725	COG0513	Belongs to the DEAD box helicase family
LXM48_04735	COG0778	Nitroreductase
LXM48_04760	COG0167	dihydroorotate dehydrogenase activity
LXM48_04790	COG4783	chaperone-mediated protein folding
LXM48_04795	COG1610	YqeY-like protein
LXM48_04810	COG1335	isochorismatase
LXM48_04825	COG0515	serine threonine protein kinase
LXM48_04825	COG2815	serine threonine protein kinase
LXM48_04865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXM48_04875	COG1643	Atp-dependent helicase
LXM48_04895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM48_04895	COG1116	anion transmembrane transporter activity
LXM48_04905	COG2223	nitrite transmembrane transporter activity
LXM48_04910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM48_04915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM48_04920	COG0243	molybdopterin cofactor binding
LXM48_04930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXM48_04965	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LXM48_04970	COG0406	alpha-ribazole phosphatase activity
LXM48_04980	COG0517	IMP dehydrogenase activity
LXM48_04980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXM48_04985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LXM48_04995	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LXM48_05000	COG1137	ATPase activity
LXM48_05020	COG4122	O-methyltransferase activity
LXM48_05030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LXM48_05070	COG2011	ABC-type metal ion transport system permease component
LXM48_05075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXM48_05085	COG0151	Belongs to the GarS family
LXM48_05090	COG0138	bifunctional purine biosynthesis protein purh
LXM48_05095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LXM48_05125	COG0445	tRNA wobble uridine modification
LXM48_05140	COG2308	Evidence 4 Homologs of previously reported genes of
LXM48_05150	COG1305	Transglutaminase-like
LXM48_05165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXM48_05170	COG0305	Participates in initiation and elongation during chromosome replication
LXM48_05185	COG0360	Binds together with S18 to 16S ribosomal RNA
LXM48_05205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXM48_05210	COG1845	cytochrome c oxidase, subunit III
LXM48_05215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXM48_05220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXM48_05250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXM48_05265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LXM48_05270	COG2890	protein-(glutamine-N5) methyltransferase activity
LXM48_05275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM48_05280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM48_05310	COG1960	acyl-CoA dehydrogenase activity
LXM48_05315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXM48_05330	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LXM48_05350	COG0477	Major facilitator Superfamily
LXM48_05355	COG0729	surface antigen
LXM48_05410	COG0786	glutamate:sodium symporter activity
LXM48_05420	COG1113	amino acid transport
LXM48_05445	COG0024	Methionine aminopeptidase
LXM48_05450	COG0583	DNA-binding transcription factor activity
LXM48_05455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXM48_05470	COG3852	Histidine kinase
LXM48_05490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXM48_05495	COG0575	Belongs to the CDS family
LXM48_05510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXM48_05530	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXM48_05545	COG2137	regulation of response to DNA damage stimulus
LXM48_05550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LXM48_05555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LXM48_05560	COG1011	Hydrolase
LXM48_05575	COG3293	Transposase
LXM48_05610	COG0702	epimerase
LXM48_05615	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LXM48_05635	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM48_05635	COG1902	pentaerythritol trinitrate reductase activity
LXM48_05650	COG2814	Major facilitator Superfamily
LXM48_05660	COG0583	DNA-binding transcription factor activity
LXM48_05680	COG0148	phosphopyruvate hydratase activity
LXM48_05695	COG0772	Belongs to the SEDS family
LXM48_05715	COG0579	oxidoreductase
LXM48_05725	COG1012	belongs to the aldehyde dehydrogenase family
LXM48_05730	COG1309	transcriptional regulator
LXM48_05735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM48_05750	COG4890	Cyd operon protein YbgT
LXM48_05755	COG1294	oxidase, subunit
LXM48_05770	COG1585	Membrane protein implicated in regulation of membrane protease activity
LXM48_05780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXM48_05800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXM48_05805	COG0569	domain protein
LXM48_05815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXM48_05820	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LXM48_05830	COG3706	GGDEF domain
LXM48_05845	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LXM48_05850	COG0542	response to heat
LXM48_05880	COG0372	Belongs to the citrate synthase family
LXM48_05890	COG2819	hydrolase of the alpha beta superfamily
LXM48_05895	COG0318	PFAM AMP-dependent synthetase and ligase
LXM48_05915	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LXM48_05915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXM48_05920	COG1254	Belongs to the acylphosphatase family
LXM48_05925	COG1047	Peptidyl-prolyl cis-trans
LXM48_05930	COG1252	NADH dehydrogenase
LXM48_05935	COG1686	Belongs to the peptidase S11 family
LXM48_05945	COG2351	hydroxyisourate hydrolase activity
LXM48_05970	COG1131	(ABC) transporter
LXM48_05975	COG0842	Transport permease protein
LXM48_05980	COG0842	Transport permease protein
LXM48_06005	COG1309	transcriptional regulator
LXM48_06070	COG1733	regulation of RNA biosynthetic process
LXM48_06075	COG0604	alcohol dehydrogenase
LXM48_06090	COG1278	Cold shock
LXM48_06150	COG2070	2-Nitropropane dioxygenase
LXM48_06175	COG3634	alkyl hydroperoxide reductase activity
LXM48_06195	COG0436	Aminotransferase
LXM48_06200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXM48_06205	COG0386	Belongs to the glutathione peroxidase family
LXM48_06230	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LXM48_06245	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LXM48_06270	COG0012	GTP binding
LXM48_06285	COG2011	ABC-type metal ion transport system permease component
LXM48_06290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXM48_06295	COG1464	Belongs to the NlpA lipoprotein family
LXM48_06300	COG1464	Belongs to the NlpA lipoprotein family
LXM48_06340	COG0204	Acyl-transferase
LXM48_06375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LXM48_06380	COG0730	response to heat
LXM48_06405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LXM48_06410	COG1944	ATP diphosphatase activity
LXM48_06415	COG2207	Transcriptional regulator
LXM48_06420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXM48_06425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LXM48_06455	COG2223	nitrite transmembrane transporter activity
LXM48_06470	COG1346	cytolysis
LXM48_06475	COG1380	Effector of murein hydrolase LrgA
LXM48_06480	COG0583	DNA-binding transcription factor activity
LXM48_06485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXM48_06515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXM48_06575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXM48_06580	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LXM48_06595	COG3300	MHYT domain
LXM48_06595	COG5001	Diguanylate cyclase
LXM48_06600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LXM48_06610	COG2814	Major facilitator Superfamily
LXM48_06625	COG1132	(ABC) transporter
LXM48_06635	COG0668	transmembrane transport
LXM48_06640	COG3122	Protein conserved in bacteria
LXM48_06660	COG0640	Transcriptional regulator
LXM48_06665	COG0596	Alpha beta hydrolase
LXM48_06670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXM48_06675	COG1335	isochorismatase
LXM48_06680	COG0251	oxidation-reduction process
LXM48_06685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM48_06690	COG2233	PERMEase
LXM48_06700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXM48_06710	COG0183	Belongs to the thiolase family
LXM48_06715	COG0583	DNA-binding transcription factor activity
LXM48_06730	COG0439	Biotin carboxylase
LXM48_06745	COG0511	ligase activity, forming carbon-carbon bonds
LXM48_06755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM48_06760	COG0183	Belongs to the thiolase family
LXM48_06765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM48_06770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXM48_06775	COG3135	benzoate transporter
LXM48_06780	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_06785	COG0633	Ferredoxin
LXM48_06785	COG0543	2 iron, 2 sulfur cluster binding
LXM48_06790	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LXM48_06795	COG4638	Rieske (2fe-2S)
LXM48_06805	COG4829	muconolactone delta-isomerase
LXM48_06810	COG4948	Mandelate Racemase Muconate Lactonizing
LXM48_06815	COG0583	DNA-binding transcription factor activity
LXM48_06820	COG2814	Major facilitator Superfamily
LXM48_06885	COG1309	transcriptional regulator
LXM48_06990	COG0596	Alpha beta hydrolase
LXM48_07060	COG0864	Transcriptional regulator
LXM48_07090	COG2814	Major facilitator Superfamily
LXM48_07100	COG2199	diguanylate cyclase activity
LXM48_07145	COG1960	acyl-CoA dehydrogenase activity
LXM48_07150	COG1960	acyl-CoA dehydrogenase activity
LXM48_07200	COG0552	protein localization to endoplasmic reticulum
LXM48_07205	COG0612	Peptidase, M16
LXM48_07230	COG0517	IMP dehydrogenase activity
LXM48_07235	COG0133	tryptophan synthase activity
LXM48_07245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXM48_07260	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LXM48_07265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXM48_07305	COG0537	adenosine 5'-monophosphoramidase activity
LXM48_07335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXM48_07340	COG0776	regulation of translation
LXM48_07355	COG1959	2 iron, 2 sulfur cluster binding
LXM48_07365	COG0822	iron-sulfur transferase activity
LXM48_07370	COG0316	Belongs to the HesB IscA family
LXM48_07400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXM48_07410	COG1027	Aspartate ammonia-lyase
LXM48_07415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXM48_07425	COG0506	proline dehydrogenase activity
LXM48_07425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXM48_07425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LXM48_07455	COG3781	membrane
LXM48_07460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXM48_07490	COG0697	spore germination
LXM48_07505	COG0126	phosphoglycerate kinase activity
LXM48_07515	COG0424	maF-like protein
LXM48_07525	COG2850	peptidyl-arginine hydroxylation
LXM48_07530	COG4585	Histidine kinase
LXM48_07535	COG2197	response regulator
LXM48_07540	COG0069	glutamate synthase activity
LXM48_07560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXM48_07565	COG1454	alcohol dehydrogenase
LXM48_07570	COG0824	Thioesterase
LXM48_07575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXM48_07595	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_07600	COG0183	Belongs to the thiolase family
LXM48_07615	COG0583	DNA-binding transcription factor activity
LXM48_07620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXM48_07630	COG3135	benzoate transporter
LXM48_07635	COG1309	transcriptional regulator
LXM48_07640	COG2076	Multidrug Resistance protein
LXM48_07655	COG0589	response to stress
LXM48_07665	COG0308	aminopeptidase N
LXM48_07690	COG1253	flavin adenine dinucleotide binding
LXM48_07710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LXM48_07715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LXM48_07730	COG2431	L-lysine efflux transmembrane transporter activity
LXM48_07745	COG0776	regulation of translation
LXM48_07765	COG0590	tRNA wobble adenosine to inosine editing
LXM48_07775	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LXM48_07810	COG0084	hydrolase, TatD family'
LXM48_07830	COG1663	tetraacyldisaccharide 4'-kinase activity
LXM48_07835	COG1132	(ABC) transporter
LXM48_07845	COG0811	peptide transport
LXM48_07850	COG1475	DNA binding
LXM48_07855	COG1192	Involved in chromosome partitioning
LXM48_07865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LXM48_07870	COG3178	'Phosphotransferase
LXM48_07880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXM48_07885	COG1923	regulation of RNA biosynthetic process
LXM48_07895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LXM48_07900	COG0802	atpase or kinase
LXM48_07905	COG0564	pseudouridine synthase activity
LXM48_07925	COG2707	UPF0756 membrane protein
LXM48_07930	COG2814	Major facilitator Superfamily
LXM48_07935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXM48_07940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXM48_07950	COG1454	alcohol dehydrogenase
LXM48_07970	COG0531	amino acid
LXM48_07975	COG4303	Ethanolamine ammonia lyase large subunit
LXM48_07980	COG4302	ethanolamine ammonia-lyase activity
LXM48_07990	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_08000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXM48_08000	COG0519	Catalyzes the synthesis of GMP from XMP
LXM48_08005	COG2353	YceI-like domain
LXM48_08010	COG0456	acetyltransferase
LXM48_08025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LXM48_08030	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LXM48_08080	COG0352	thiamine-phosphate diphosphorylase activity
LXM48_08115	COG0612	Peptidase, M16
LXM48_08125	COG1823	symporter activity
LXM48_08130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM48_08155	COG0582	viral genome integration into host DNA
LXM48_08165	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LXM48_08185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LXM48_08250	COG1570	exodeoxyribonuclease VII activity
LXM48_08265	COG1877	trehalose-phosphatase activity
LXM48_08270	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LXM48_08275	COG2223	nitrite transmembrane transporter activity
LXM48_08320	COG2323	membrane
LXM48_08370	COG1271	oxidase subunit
LXM48_08375	COG1294	oxidase, subunit
LXM48_08385	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_08395	COG1022	Amp-dependent synthetase and ligase
LXM48_08490	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_08495	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LXM48_08515	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_08570	COG0714	Associated with various cellular activities
LXM48_08580	COG2879	small protein
LXM48_08585	COG1966	Carbon starvation protein
LXM48_08590	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LXM48_08610	COG0254	rRNA binding
LXM48_08630	COG1067	ATP-dependent peptidase activity
LXM48_08635	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LXM48_08640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXM48_08645	COG0616	signal peptide processing
LXM48_08650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXM48_08660	COG0573	inorganic phosphate transmembrane transporter activity
LXM48_08665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXM48_08670	COG0076	glutamate decarboxylase activity
LXM48_08675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXM48_08685	COG4772	TonB-dependent receptor
LXM48_08690	COG0671	phosphoesterase, PA-phosphatase related
LXM48_08695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXM48_08705	COG1733	regulation of RNA biosynthetic process
LXM48_08710	COG0702	epimerase
LXM48_08745	COG0556	nucleotide-excision repair
LXM48_08760	COG2199	diguanylate cyclase activity
LXM48_08770	COG0436	Aminotransferase
LXM48_08810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LXM48_08815	COG1381	Involved in DNA repair and RecF pathway recombination
LXM48_08825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXM48_08830	COG0571	ribonuclease III activity
LXM48_08840	COG0681	Belongs to the peptidase S26 family
LXM48_08885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXM48_08905	COG3772	lysozyme
LXM48_08960	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
LXM48_09005	COG4387	Mu-like prophage protein GP36
LXM48_09035	COG4383	Mu-like prophage protein gp29
LXM48_09215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXM48_09235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXM48_09245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LXM48_09260	COG4208	sulfate ABC transporter
LXM48_09265	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LXM48_09270	COG0583	DNA-binding transcription factor activity
LXM48_09290	COG0602	queuosine metabolic process
LXM48_09295	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LXM48_09310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXM48_09320	COG0583	DNA-binding transcription factor activity
LXM48_09325	COG2353	YceI-like domain
LXM48_09330	COG1051	belongs to the nudix hydrolase family
LXM48_09330	COG1056	cytidyltransferase-related domain
LXM48_09335	COG1024	Enoyl-CoA hydratase
LXM48_09340	COG0778	Nitroreductase
LXM48_09345	COG3323	Protein of unknown function (DUF1653)
LXM48_09345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXM48_09355	COG0047	phosphoribosylformylglycinamidine synthase activity
LXM48_09355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXM48_09370	COG2255	four-way junction helicase activity
LXM48_09375	COG0824	Thioesterase
LXM48_09395	COG0823	Involved in the tonB-independent uptake of proteins
LXM48_09415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXM48_09445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXM48_09450	COG0628	permease
LXM48_09455	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LXM48_09460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXM48_09480	COG0658	competence protein
LXM48_09480	COG2333	competence protein COMEC
LXM48_09485	COG1136	(ABC) transporter
LXM48_09490	COG4591	ABC-type transport system involved in lipoprotein release permease component
LXM48_09505	COG1671	Belongs to the UPF0178 family
LXM48_09520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXM48_09525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LXM48_09530	COG1960	acyl-CoA dehydrogenase activity
LXM48_09595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LXM48_09600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXM48_09605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXM48_09610	COG1716	ATPase activity
LXM48_09610	COG5001	Diguanylate cyclase
LXM48_09615	COG0281	malic enzyme
LXM48_09615	COG0280	phosphate acetyltransferase
LXM48_09645	COG1902	pentaerythritol trinitrate reductase activity
LXM48_09645	COG0446	pyridine nucleotide-disulphide oxidoreductase
LXM48_09650	COG0277	FAD linked oxidase domain protein
LXM48_09660	COG2186	Transcriptional regulator
LXM48_09675	COG5001	Diguanylate cyclase
LXM48_09675	COG4251	negative regulation of phosphorylation
LXM48_09675	COG3706	GGDEF domain
LXM48_09675	COG2203	Gaf domain
LXM48_09680	COG0418	dihydroorotase activity
LXM48_09685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXM48_09705	COG0833	amino acid
LXM48_09730	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LXM48_09745	COG4172	Belongs to the ABC transporter superfamily
LXM48_09750	COG4239	(ABC) transporter, permease
LXM48_09755	COG4174	ABC transporter (Permease)
LXM48_09760	COG4166	transmembrane transport
LXM48_09765	COG1388	LysM domain
LXM48_09765	COG0741	lytic transglycosylase activity
LXM48_09780	COG2816	NAD+ diphosphatase activity
LXM48_09785	COG0657	acetylesterase activity
LXM48_09805	COG0583	DNA-binding transcription factor activity
LXM48_09825	COG0753	catalase activity
LXM48_09840	COG0789	Transcriptional regulator
LXM48_09860	COG1686	Belongs to the peptidase S11 family
LXM48_09865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXM48_09870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXM48_09875	COG2267	carboxylic ester hydrolase activity
LXM48_09880	COG0671	phosphoesterase, PA-phosphatase related
LXM48_09880	COG2453	phosphatase
LXM48_09895	COG4589	Belongs to the CDS family
LXM48_09910	COG2915	High frequency lysogenization protein hflD homolog
LXM48_09930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM48_09935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXM48_09945	COG0006	proline dipeptidase activity
LXM48_09995	COG3706	GGDEF domain
LXM48_10010	COG1785	Belongs to the alkaline phosphatase family
LXM48_10015	COG1785	Belongs to the alkaline phosphatase family
LXM48_10025	COG4770	biotin carboxylase activity
LXM48_10050	COG0583	DNA-binding transcription factor activity
LXM48_10060	COG2217	Heavy metal translocating P-type atpase
LXM48_10070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LXM48_10085	COG2234	aminopeptidase activity
LXM48_10095	COG3384	dioxygenase
LXM48_10105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXM48_10110	COG2878	Part of a membrane complex involved in electron transport
LXM48_10115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXM48_10140	COG0768	penicillin binding
LXM48_10145	COG0742	ribosomal rna small subunit methyltransferase
LXM48_10170	COG3119	arylsulfatase activity
LXM48_10175	COG0641	radical SAM
LXM48_10195	COG1597	lipid kinase activity
LXM48_10215	COG0477	Major facilitator Superfamily
LXM48_10255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM48_10255	COG0604	alcohol dehydrogenase
LXM48_10255	COG3321	synthase
LXM48_10255	COG4221	oxidoreductase activity
LXM48_10270	COG1695	Transcriptional regulator
LXM48_10285	COG0210	DNA helicase
LXM48_10320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXM48_10325	COG1773	rubredoxin
LXM48_10330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXM48_10340	COG0583	DNA-binding transcription factor activity
LXM48_10360	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LXM48_10365	COG4181	ATPase activity
LXM48_10390	COG4771	TonB-dependent receptor
LXM48_10415	COG0306	phosphate transporter
LXM48_10430	COG2223	nitrite transmembrane transporter activity
LXM48_10435	COG2207	Transcriptional regulator
LXM48_10440	COG0242	peptide deformylase activity
LXM48_10445	COG0477	Major facilitator Superfamily
LXM48_10490	COG2203	Gaf domain
LXM48_10490	COG2199	diguanylate cyclase activity
LXM48_10500	COG4681	YaeQ
LXM48_10505	COG0523	cobalamin synthesis protein
LXM48_10515	COG1607	acyl-coa hydrolase
LXM48_10520	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXM48_10530	COG1115	amino acid carrier protein
LXM48_10535	COG0786	glutamate:sodium symporter activity
LXM48_10550	COG2814	Major facilitator Superfamily
LXM48_10560	COG1289	transmembrane transporter activity
LXM48_10570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXM48_10640	COG2832	Protein of unknown function (DUF454)
LXM48_10655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXM48_10665	COG0784	Response regulator, receiver
LXM48_10665	COG2198	Histidine kinase
LXM48_10665	COG0643	Histidine kinase
LXM48_10670	COG0840	transmembrane signaling receptor activity
LXM48_10740	COG2358	TRAP transporter, solute receptor (TAXI family
LXM48_10755	COG0489	protein tyrosine kinase activity
LXM48_10775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM48_10775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM48_10795	COG4716	Myosin-crossreactive antigen
LXM48_10825	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LXM48_10830	COG2081	HI0933 family
LXM48_10845	COG0668	transmembrane transport
LXM48_10865	COG0765	amino acid transport
LXM48_10870	COG0765	amino acid transport
LXM48_10875	COG1126	abc transporter atp-binding protein
LXM48_10885	COG0004	ammonium transporteR
LXM48_10900	COG0642	Histidine kinase
LXM48_10905	COG0745	RESPONSE REGULATOR receiver
LXM48_10930	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXM48_10945	COG0142	geranyltranstransferase activity
LXM48_10950	COG2828	Protein conserved in bacteria
LXM48_10955	COG1113	amino acid transport
LXM48_10975	COG1113	amino acid transport
LXM48_10995	COG0625	glutathione transferase activity
LXM48_11010	COG0431	NADPH-dependent FMN reductase
LXM48_11015	COG0798	PFAM Bile acid sodium symporter
LXM48_11025	COG0640	Transcriptional regulator
LXM48_11075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXM48_11090	COG0424	maF-like protein
LXM48_11095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LXM48_11100	COG1792	Involved in formation and maintenance of cell shape
LXM48_11105	COG1077	Cell shape determining protein MreB Mrl
LXM48_11110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXM48_11120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXM48_11155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LXM48_11165	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_11170	COG2610	gluconate transmembrane transporter activity
LXM48_11175	COG0583	DNA-binding transcription factor activity
LXM48_11185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXM48_11195	COG4772	TonB-dependent receptor
LXM48_11215	COG1294	oxidase, subunit
LXM48_11225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXM48_11235	COG1346	cytolysis
LXM48_11265	COG2130	NADP-dependent
LXM48_11270	COG1309	transcriptional regulator
LXM48_11280	COG1902	pentaerythritol trinitrate reductase activity
LXM48_11290	COG1979	alcohol dehydrogenase
LXM48_11300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LXM48_11320	COG0475	glutathione-regulated potassium exporter activity
LXM48_11320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXM48_11325	COG0604	alcohol dehydrogenase
LXM48_11325	COG3321	synthase
LXM48_11330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LXM48_11335	COG0583	DNA-binding transcription factor activity
LXM48_11340	COG4221	oxidoreductase activity
LXM48_11370	COG3046	protein related to deoxyribodipyrimidine photolyase
LXM48_11395	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_11435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXM48_11440	COG2814	Major facilitator Superfamily
LXM48_11445	COG1566	PFAM secretion protein HlyD family protein
LXM48_11450	COG2050	protein possibly involved in aromatic compounds catabolism
LXM48_11465	COG1090	epimerase
LXM48_11475	COG2203	Gaf domain
LXM48_11475	COG3706	GGDEF domain
LXM48_11475	COG4251	negative regulation of phosphorylation
LXM48_11475	COG5001	Diguanylate cyclase
LXM48_11480	COG0420	3'-5' exonuclease activity
LXM48_11510	COG0735	belongs to the Fur family
LXM48_11515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LXM48_11520	COG2914	Belongs to the UPF0125 (RnfH) family
LXM48_11535	COG0121	glutamine amidotransferase
LXM48_11550	COG0756	dUTP diphosphatase activity
LXM48_11555	COG0210	DNA helicase
LXM48_11560	COG2885	chlorophyll binding
LXM48_11565	COG0204	Acyl-transferase
LXM48_11575	COG0850	regulation of cytokinetic process
LXM48_11580	COG2894	cell division
LXM48_11585	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LXM48_11600	COG1674	ftsk spoiiie
LXM48_11600	COG0531	amino acid
LXM48_11605	COG0492	ferredoxin-NADP+ reductase activity
LXM48_11610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LXM48_11620	COG0456	acetyltransferase
LXM48_11645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LXM48_11660	COG1981	membrane
LXM48_11670	COG1113	amino acid transport
LXM48_11675	COG0251	oxidation-reduction process
LXM48_11705	COG0352	thiamine-phosphate diphosphorylase activity
LXM48_11705	COG0351	phosphomethylpyrimidine kinase
LXM48_11705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXM48_11715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXM48_11740	COG2132	Multicopper oxidase
LXM48_11750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXM48_11785	COG1968	undecaprenyl-diphosphatase activity
LXM48_11790	COG1214	PFAM Peptidase M22, glycoprotease
LXM48_11795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXM48_11800	COG0494	nUDIX hydrolase
LXM48_11850	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXM48_11860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXM48_11930	COG2853	Lipoprotein
LXM48_11935	COG2208	phosphoserine phosphatase activity
LXM48_11945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXM48_11955	COG1764	response to oxidative stress
LXM48_12000	COG0037	tRNA processing
LXM48_12010	COG0248	Ppx GppA phosphatase
LXM48_12035	COG0072	phenylalanine-tRNA ligase activity
LXM48_12085	COG1238	metal cluster binding
LXM48_12095	COG0625	glutathione transferase activity
LXM48_12115	COG0318	PFAM AMP-dependent synthetase and ligase
LXM48_12120	COG3028	Belongs to the UPF0307 family
LXM48_12130	COG1660	Displays ATPase and GTPase activities
LXM48_12135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LXM48_12145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXM48_12150	COG0617	tRNA 3'-terminal CCA addition
LXM48_12155	COG1555	photosystem II stabilization
LXM48_12160	COG3956	TIGRFAM MazG family protein
LXM48_12170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXM48_12185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXM48_12190	COG0784	Response regulator, receiver
LXM48_12190	COG2205	protein histidine kinase activity
LXM48_12190	COG5002	protein histidine kinase activity
LXM48_12195	COG1024	Enoyl-CoA hydratase
LXM48_12200	COG2084	Dehydrogenase
LXM48_12205	COG3622	Belongs to the hyi family
LXM48_12220	COG0004	ammonium transporteR
LXM48_12245	COG2814	Major facilitator Superfamily
LXM48_12265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXM48_12270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LXM48_12275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXM48_12285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXM48_12330	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LXM48_12350	COG2826	transposase and inactivated derivatives, IS30 family
LXM48_12355	COG0732	type I restriction modification DNA specificity domain
LXM48_12365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LXM48_12380	COG0174	glutamine synthetase
LXM48_12390	COG0745	RESPONSE REGULATOR receiver
LXM48_12395	COG2205	protein histidine kinase activity
LXM48_12405	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LXM48_12410	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LXM48_12490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXM48_12505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LXM48_12515	COG0084	hydrolase, TatD family'
LXM48_12530	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LXM48_12545	COG0793	Belongs to the peptidase S41A family
LXM48_12570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXM48_12575	COG0280	phosphate acetyltransferase
LXM48_12575	COG0857	belongs to the CobB CobQ family
LXM48_12595	COG2318	DinB family
LXM48_12615	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LXM48_12615	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LXM48_12635	COG0740	serine-type endopeptidase activity
LXM48_12645	COG4771	TonB-dependent receptor
LXM48_12650	COG4774	siderophore transport
LXM48_12665	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXM48_12675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LXM48_12675	COG2813	Specifically methylates the guanine in position
LXM48_12780	COG0788	formyltetrahydrofolate deformylase activity
LXM48_12805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXM48_12805	COG4651	solute:proton antiporter activity
LXM48_12830	COG0210	DNA helicase
LXM48_12835	COG1929	Belongs to the glycerate kinase type-1 family
LXM48_12875	COG2900	Belongs to the SlyX family
LXM48_12880	COG0488	(ABC) transporter
LXM48_12885	COG1560	Kdo2-lipid A biosynthetic process
LXM48_12940	COG0473	3-isopropylmalate dehydrogenase activity
LXM48_12955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LXM48_12965	COG0583	DNA-binding transcription factor activity
LXM48_13000	COG1280	lysine exporter protein (LysE YggA)
LXM48_13020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LXM48_13035	COG0583	DNA-binding transcription factor activity
LXM48_13050	COG0564	pseudouridine synthase activity
LXM48_13055	COG1530	ribonuclease E activity
LXM48_13060	COG0318	PFAM AMP-dependent synthetase and ligase
LXM48_13085	COG1983	PspC domain protein
LXM48_13105	COG0751	glycine-tRNA ligase activity
LXM48_13140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXM48_13155	COG2226	methyltransferase
LXM48_13170	COG0493	'glutamate synthase
LXM48_13170	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LXM48_13180	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LXM48_13190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXM48_13195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXM48_13205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXM48_13215	COG0644	oxidoreductase
LXM48_13215	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LXM48_13235	COG0425	Belongs to the sulfur carrier protein TusA family
LXM48_13240	COG4535	Mg2 and Co2 transporter CorC
LXM48_13245	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LXM48_13250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXM48_13270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXM48_13280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LXM48_13300	COG2841	Protein conserved in bacteria
LXM48_13305	COG0598	Magnesium transport protein CorA
LXM48_13310	COG1185	polyribonucleotide nucleotidyltransferase activity
LXM48_13320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXM48_13325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXM48_13330	COG1074	ATP-dependent DNA helicase activity
LXM48_13335	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LXM48_13365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LXM48_13380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXM48_13390	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXM48_13395	COG2111	Na H antiporter
LXM48_13395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXM48_13400	COG1006	Multisubunit Na H antiporter MnhC subunit
LXM48_13405	COG0651	ATP synthesis coupled electron transport
LXM48_13410	COG1863	multisubunit Na H antiporter MnhE subunit
LXM48_13415	COG2212	antiporter activity
LXM48_13420	COG1320	monovalent cation:proton antiporter activity
LXM48_13425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LXM48_13430	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LXM48_13435	COG0195	Participates in both transcription termination and antitermination
LXM48_13495	COG0237	dephospho-CoA kinase activity
LXM48_13505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXM48_13515	COG0497	DNA recombination
LXM48_13520	COG1678	Uncharacterized ACR, COG1678
LXM48_13525	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXM48_13540	COG1289	transmembrane transporter activity
LXM48_13555	COG1132	(ABC) transporter
LXM48_13560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXM48_13635	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXM48_13665	COG0326	Molecular chaperone. Has ATPase activity
LXM48_13675	COG3047	cAMP biosynthetic process
LXM48_13680	COG2056	Na+-H+ antiporter family
LXM48_13705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LXM48_13710	COG0085	RNA polymerase activity
LXM48_13715	COG0222	ribosome binding
LXM48_13720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LXM48_13725	COG0081	regulation of translation
LXM48_13730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LXM48_13780	COG0546	phosphoglycolate phosphatase activity
LXM48_13810	COG0824	Thioesterase
LXM48_13830	COG0181	hydroxymethylbilane synthase activity
LXM48_13840	COG3275	phosphorelay sensor kinase activity
LXM48_13860	COG1538	Outer membrane efflux protein
LXM48_13870	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LXM48_13880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXM48_13885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXM48_13890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXM48_13895	COG0772	Belongs to the SEDS family
LXM48_13900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXM48_13920	COG4974	Belongs to the 'phage' integrase family
LXM48_13925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXM48_13935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXM48_13945	COG2197	response regulator
LXM48_13960	COG0793	Belongs to the peptidase S41A family
LXM48_13965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LXM48_13970	COG0795	lipopolysaccharide-transporting ATPase activity
LXM48_13975	COG0795	lipopolysaccharide-transporting ATPase activity
LXM48_13995	COG0586	Pfam SNARE associated Golgi protein
LXM48_14010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXM48_14010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXM48_14020	COG0004	ammonium transporteR
LXM48_14025	COG0347	Belongs to the P(II) protein family
LXM48_14035	COG0606	chelatase, subunit chli
LXM48_14055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LXM48_14070	COG0318	PFAM AMP-dependent synthetase and ligase
LXM48_14080	COG0477	Major facilitator Superfamily
LXM48_14085	COG2860	membrane
LXM48_14090	COG3012	SEC-C Motif Domain Protein
LXM48_14095	COG1253	flavin adenine dinucleotide binding
LXM48_14115	COG2814	Major facilitator Superfamily
LXM48_14125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXM48_14200	COG0758	DNA mediated transformation
LXM48_14210	COG0697	spore germination
LXM48_14220	COG0386	Belongs to the glutathione peroxidase family
LXM48_14255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LXM48_14305	COG1121	(ABC) transporter
LXM48_14310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXM48_14315	COG1683	Conserved Protein
LXM48_14325	COG2837	iron assimilation
LXM48_14350	COG0281	malic enzyme
LXM48_14375	COG2267	carboxylic ester hydrolase activity
LXM48_14400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXM48_14400	COG0519	Catalyzes the synthesis of GMP from XMP
LXM48_14415	COG0586	Pfam SNARE associated Golgi protein
LXM48_14430	COG1192	Involved in chromosome partitioning
LXM48_14440	COG0271	Belongs to the BolA IbaG family
LXM48_14490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXM48_14520	COG1132	(ABC) transporter
LXM48_14525	COG1538	Outer membrane efflux protein
LXM48_14535	COG4372	Transposase
LXM48_14550	COG2963	transposase activity
LXM48_14585	COG4628	conserved protein (DUF2132)
LXM48_14595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXM48_14600	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_14640	COG2986	histidine ammonia-lyase
LXM48_14655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXM48_14665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXM48_14685	COG0583	DNA-binding transcription factor activity
LXM48_14690	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LXM48_14705	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LXM48_14715	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LXM48_14720	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXM48_14730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LXM48_14770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXM48_14785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXM48_14790	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXM48_14820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LXM48_14825	COG2244	polysaccharide biosynthetic process
LXM48_14840	COG1091	dTDP-4-dehydrorhamnose reductase activity
LXM48_14845	COG1088	dTDP-glucose 4,6-dehydratase activity
LXM48_14855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXM48_14865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXM48_14870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXM48_14875	COG0438	transferase activity, transferring glycosyl groups
LXM48_14880	COG0438	transferase activity, transferring glycosyl groups
LXM48_14885	COG0438	transferase activity, transferring glycosyl groups
LXM48_14910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LXM48_14915	COG1596	polysaccharide export
LXM48_14945	COG0728	peptidoglycan biosynthetic process
LXM48_14950	COG3023	N-Acetylmuramoyl-L-alanine amidase
LXM48_14960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LXM48_14970	COG3307	-O-antigen
LXM48_14975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXM48_14980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LXM48_14985	COG0546	phosphoglycolate phosphatase activity
LXM48_14990	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_15015	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LXM48_15015	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LXM48_15020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM48_15025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXM48_15030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXM48_15035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXM48_15040	COG1116	anion transmembrane transporter activity
LXM48_15045	COG1309	transcriptional regulator
LXM48_15060	COG0196	riboflavin kinase activity
LXM48_15065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXM48_15070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LXM48_15075	COG1047	Peptidyl-prolyl cis-trans
LXM48_15095	COG2133	pyrroloquinoline quinone binding
LXM48_15125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXM48_15135	COG0657	acetylesterase activity
LXM48_15195	COG0488	(ABC) transporter
LXM48_15205	COG0187	DNA topoisomerase II activity
LXM48_15215	COG0592	DNA-directed DNA polymerase activity
LXM48_15220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXM48_15235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXM48_15240	COG0706	membrane insertase activity
LXM48_15260	COG1230	cation diffusion facilitator family transporter
LXM48_15280	COG0402	S-adenosylhomocysteine deaminase activity
LXM48_15290	COG0754	glutathionylspermidine amidase activity
LXM48_15300	COG0861	Integral membrane protein TerC family
LXM48_15325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXM48_15340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXM48_15345	COG2951	lytic endotransglycosylase activity
LXM48_15350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LXM48_15355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXM48_15385	COG2814	Major facilitator Superfamily
LXM48_15395	COG0733	neurotransmitter:sodium symporter activity
LXM48_15420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXM48_15420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXM48_15435	COG0129	dihydroxy-acid dehydratase activity
LXM48_15445	COG4774	siderophore transport
LXM48_15455	COG0583	DNA-binding transcription factor activity
LXM48_15460	COG2233	PERMEase
LXM48_15470	COG1309	transcriptional regulator
LXM48_15475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXM48_15490	COG0484	heat shock protein binding
LXM48_15515	COG0436	Aminotransferase
LXM48_15520	COG1064	alcohol dehydrogenase
LXM48_15525	COG2818	Glycosylase
LXM48_15555	COG5487	UPF0391 membrane protein
LXM48_15560	COG2983	Belongs to the UPF0260 family
LXM48_15565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXM48_15570	COG1522	sequence-specific DNA binding
LXM48_15580	COG4160	amino acid transport
LXM48_15585	COG4215	(ABC) transporter
LXM48_15605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXM48_15610	COG1335	isochorismatase
LXM48_15615	COG0385	Bile acid
LXM48_15685	COG0534	Mate efflux family protein
LXM48_15690	COG0436	Aminotransferase
LXM48_15695	COG2733	membrane
LXM48_15710	COG2918	glutathione biosynthetic process
LXM48_15715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LXM48_15725	COG3150	esterase
LXM48_15820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXM48_15835	COG1393	Belongs to the ArsC family
LXM48_15840	COG0708	Exodeoxyribonuclease III
LXM48_15865	COG1846	Transcriptional regulator
LXM48_15870	COG0386	Belongs to the glutathione peroxidase family
LXM48_15875	COG0189	ligase activity
LXM48_15885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXM48_15895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXM48_15905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXM48_15935	COG2119	membrane
LXM48_15940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXM48_15940	COG0426	domain, Protein
LXM48_15965	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXM48_15990	COG1902	pentaerythritol trinitrate reductase activity
LXM48_15995	COG1519	Transferase
LXM48_16000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXM48_16005	COG0668	transmembrane transport
LXM48_16010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXM48_16015	COG0307	riboflavin synthase, alpha
LXM48_16020	COG1028	Short-chain dehydrogenase reductase Sdr
LXM48_16035	COG0431	NADPH-dependent FMN reductase
LXM48_16050	COG2205	protein histidine kinase activity
LXM48_16050	COG0784	Response regulator, receiver
LXM48_16055	COG3162	membrane
LXM48_16070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXM48_16080	COG3706	GGDEF domain
LXM48_16100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXM48_16100	COG0351	phosphomethylpyrimidine kinase
LXM48_16100	COG0352	thiamine-phosphate diphosphorylase activity
LXM48_16110	COG2814	Major facilitator Superfamily
LXM48_16115	COG0629	single-stranded DNA binding
LXM48_16145	COG2132	Multicopper oxidase
LXM48_16160	COG2205	protein histidine kinase activity
LXM48_16165	COG3174	membrane
LXM48_16170	COG2217	Heavy metal translocating P-type atpase
LXM48_16265	COG0629	single-stranded DNA binding
LXM48_16275	COG0583	DNA-binding transcription factor activity