locus-tag	class	description
CFH90_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFH90_00010	COG0592	DNA-directed DNA polymerase activity
CFH90_00020	COG0187	DNA topoisomerase II activity
CFH90_00035	COG0488	(ABC) transporter
CFH90_00105	COG1943	Transposase
CFH90_00115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFH90_00145	COG2814	Major facilitator Superfamily
CFH90_00155	COG2801	Transposase and inactivated derivatives
CFH90_00160	COG0733	neurotransmitter:sodium symporter activity
CFH90_00185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFH90_00185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFH90_00200	COG0129	dihydroxy-acid dehydratase activity
CFH90_00210	COG4774	siderophore transport
CFH90_00220	COG0583	DNA-binding transcription factor activity
CFH90_00225	COG2233	PERMEase
CFH90_00235	COG1309	transcriptional regulator
CFH90_00260	COG0484	heat shock protein binding
CFH90_00270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFH90_00290	COG1064	alcohol dehydrogenase
CFH90_00295	COG2818	Glycosylase
CFH90_00325	COG5487	UPF0391 membrane protein
CFH90_00330	COG2983	Belongs to the UPF0260 family
CFH90_00335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFH90_00340	COG1943	Transposase
CFH90_00365	COG4160	amino acid transport
CFH90_00370	COG4215	(ABC) transporter
CFH90_00375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFH90_00395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFH90_00405	COG1335	isochorismatase
CFH90_00410	COG0385	Bile acid
CFH90_00480	COG0534	Mate efflux family protein
CFH90_00485	COG0436	Aminotransferase
CFH90_00490	COG2733	membrane
CFH90_00505	COG2918	glutathione biosynthetic process
CFH90_00510	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CFH90_00520	COG3150	esterase
CFH90_00540	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFH90_00555	COG0410	ABC transporter
CFH90_00615	COG3706	GGDEF domain
CFH90_00625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFH90_00640	COG1393	Belongs to the ArsC family
CFH90_00645	COG0708	Exodeoxyribonuclease III
CFH90_00655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFH90_00670	COG1846	Transcriptional regulator
CFH90_00675	COG0386	Belongs to the glutathione peroxidase family
CFH90_00680	COG0189	ligase activity
CFH90_00690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFH90_00700	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFH90_00710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFH90_00735	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFH90_00740	COG2119	membrane
CFH90_00745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_00745	COG0426	domain, Protein
CFH90_00770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFH90_00795	COG1902	pentaerythritol trinitrate reductase activity
CFH90_00800	COG1519	Transferase
CFH90_00805	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFH90_00810	COG0668	transmembrane transport
CFH90_00815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFH90_00820	COG0307	riboflavin synthase, alpha
CFH90_00825	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_00840	COG0431	NADPH-dependent FMN reductase
CFH90_00855	COG2205	protein histidine kinase activity
CFH90_00855	COG0784	Response regulator, receiver
CFH90_00860	COG3162	membrane
CFH90_00875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFH90_00900	COG3706	GGDEF domain
CFH90_00920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFH90_00920	COG0352	thiamine-phosphate diphosphorylase activity
CFH90_00920	COG0351	phosphomethylpyrimidine kinase
CFH90_00930	COG2814	Major facilitator Superfamily
CFH90_00935	COG0629	single-stranded DNA binding
CFH90_00955	COG4372	Transposase
CFH90_00960	COG0583	DNA-binding transcription factor activity
CFH90_00980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFH90_00985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_00990	COG0450	alkyl hydroperoxide reductase
CFH90_01145	COG0582	viral genome integration into host DNA
CFH90_01155	COG3158	transport of potassium into the cell
CFH90_01260	COG1840	ABC-type Fe3 transport system, periplasmic component
CFH90_01265	COG3842	ATPase activity
CFH90_01310	COG2801	Transposase and inactivated derivatives
CFH90_01345	COG3077	Addiction module antitoxin, RelB DinJ family
CFH90_01350	COG3706	GGDEF domain
CFH90_01355	COG0753	catalase activity
CFH90_01360	COG2801	Transposase and inactivated derivatives
CFH90_01380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFH90_01385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_01420	COG2814	Major facilitator Superfamily
CFH90_01500	COG2217	Heavy metal translocating P-type atpase
CFH90_01505	COG3174	membrane
CFH90_01510	COG2205	protein histidine kinase activity
CFH90_01525	COG2132	Multicopper oxidase
CFH90_01555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFH90_01580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFH90_01585	COG1278	Cold shock
CFH90_01620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFH90_01655	COG0427	acetyl-CoA hydrolase
CFH90_01660	COG2205	protein histidine kinase activity
CFH90_01665	COG0745	RESPONSE REGULATOR receiver
CFH90_01685	COG4221	oxidoreductase activity
CFH90_01695	COG0488	(ABC) transporter
CFH90_01715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_01760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFH90_01765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CFH90_01775	COG2226	methyltransferase
CFH90_01825	COG0069	glutamate synthase activity
CFH90_01825	COG0070	glutamate synthase
CFH90_01825	COG0067	glutamate synthase
CFH90_01830	COG0493	'glutamate synthase
CFH90_01840	COG1704	LemA family
CFH90_01845	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CFH90_01930	COG4969	Belongs to the N-Me-Phe pilin family
CFH90_01970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_01975	COG1758	RNA polymerase activity
CFH90_01980	COG0194	GDP metabolic process
CFH90_02030	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFH90_02040	COG0335	large ribosomal subunit rRNA binding
CFH90_02055	COG5380	lipid catabolic process
CFH90_02060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFH90_02080	COG5006	permease, DMT superfamily
CFH90_02085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFH90_02090	COG0277	FAD linked oxidase domain protein
CFH90_02115	COG3335	DDE superfamily endonuclease
CFH90_02125	COG2814	Major facilitator Superfamily
CFH90_02130	COG1289	transmembrane transporter activity
CFH90_02135	COG2032	superoxide dismutase activity
CFH90_02140	COG0628	permease
CFH90_02145	COG1192	Involved in chromosome partitioning
CFH90_02155	COG2226	methyltransferase
CFH90_02170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFH90_02175	COG0254	rRNA binding
CFH90_02180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFH90_02190	COG0534	Mate efflux family protein
CFH90_02200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFH90_02220	COG1910	domain protein
CFH90_02225	COG1960	acyl-CoA dehydrogenase activity
CFH90_02250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFH90_02270	COG0513	Belongs to the DEAD box helicase family
CFH90_02275	COG1127	ABC transporter
CFH90_02280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFH90_02285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CFH90_02290	COG2854	intermembrane phospholipid transfer
CFH90_02300	COG0598	Magnesium transport protein CorA
CFH90_02310	COG0494	nUDIX hydrolase
CFH90_02315	COG1040	competence protein
CFH90_02320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFH90_02345	COG2937	Belongs to the GPAT DAPAT family
CFH90_02350	COG1946	Acyl-CoA thioesterase
CFH90_02355	COG1301	dicarboxylic acid transport
CFH90_02370	COG1959	2 iron, 2 sulfur cluster binding
CFH90_02375	COG1017	nitric oxide dioxygenase activity
CFH90_02375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFH90_02380	COG0433	COG0433 Predicted ATPase
CFH90_02400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFH90_02405	COG0088	Forms part of the polypeptide exit tunnel
CFH90_02420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFH90_02425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFH90_02470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFH90_02475	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFH90_02485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFH90_02505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFH90_02510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFH90_02515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFH90_02525	COG0202	RNA polymerase activity
CFH90_02530	COG0203	ribosomal protein L17
CFH90_02535	COG2072	flavoprotein involved in K transport
CFH90_02545	COG1960	acyl-CoA dehydrogenase activity
CFH90_02550	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CFH90_02580	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CFH90_02585	COG0339	signal peptide processing
CFH90_02590	COG2720	vancomycin resistance protein
CFH90_02595	COG0557	exoribonuclease II activity
CFH90_02630	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFH90_02645	COG1295	ribonuclease BN
CFH90_02660	COG3706	GGDEF domain
CFH90_02690	COG4773	Receptor
CFH90_02700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFH90_02705	COG1702	phosphate starvation-inducible protein PhoH
CFH90_02710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFH90_02715	COG0741	lytic transglycosylase activity
CFH90_02715	COG1196	nuclear chromosome segregation
CFH90_02715	COG0739	heme binding
CFH90_02725	COG0039	L-malate dehydrogenase activity
CFH90_02750	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFH90_02755	COG1183	phosphatidylcholine synthase activity
CFH90_02800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_02800	COG3453	Protein conserved in bacteria
CFH90_02815	COG1607	acyl-coa hydrolase
CFH90_02830	COG1666	GTP binding
CFH90_02850	COG2350	Protein conserved in bacteria
CFH90_02860	COG0613	PHP domain protein
CFH90_02865	COG3781	membrane
CFH90_02875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFH90_02900	COG1162	GTPase activity
CFH90_02905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CFH90_02935	COG0577	efflux transmembrane transporter activity
CFH90_02935	COG1136	(ABC) transporter
CFH90_02940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_02965	COG0028	Belongs to the TPP enzyme family
CFH90_02970	COG0440	acetolactate synthase activity
CFH90_03045	COG1426	Protein conserved in bacteria
CFH90_03065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_03090	COG1862	Preprotein translocase
CFH90_03100	COG1704	LemA family
CFH90_03110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFH90_03125	COG5002	protein histidine kinase activity
CFH90_03130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFH90_03200	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFH90_03230	COG3223	Belongs to the PsiE family
CFH90_03265	COG1960	acyl-CoA dehydrogenase activity
CFH90_03270	COG1960	acyl-CoA dehydrogenase activity
CFH90_03280	COG2205	protein histidine kinase activity
CFH90_03285	COG0745	RESPONSE REGULATOR receiver
CFH90_03290	COG1113	amino acid transport
CFH90_03295	COG2315	Protein conserved in bacteria
CFH90_03300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFH90_03320	COG2096	Adenosyltransferase
CFH90_03325	COG4206	TonB-dependent receptor
CFH90_03335	COG0133	tryptophan synthase activity
CFH90_03350	COG3083	sulfuric ester hydrolase activity
CFH90_03380	COG0285	dihydrofolate synthase activity
CFH90_03400	COG0450	alkyl hydroperoxide reductase
CFH90_03420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFH90_03425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFH90_03455	COG2199	diguanylate cyclase activity
CFH90_03490	COG2814	Major facilitator Superfamily
CFH90_03515	COG0693	protein deglycase activity
CFH90_03555	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFH90_03565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFH90_03630	COG0494	nUDIX hydrolase
CFH90_03635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFH90_03640	COG1214	PFAM Peptidase M22, glycoprotease
CFH90_03645	COG1968	undecaprenyl-diphosphatase activity
CFH90_03680	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CFH90_03715	COG2076	Multidrug Resistance protein
CFH90_03720	COG2076	Multidrug Resistance protein
CFH90_03725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFH90_03750	COG1522	sequence-specific DNA binding
CFH90_03755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFH90_03765	COG0251	oxidation-reduction process
CFH90_03770	COG1113	amino acid transport
CFH90_03795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFH90_03810	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFH90_03820	COG0456	acetyltransferase
CFH90_03830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFH90_03835	COG0492	ferredoxin-NADP+ reductase activity
CFH90_03840	COG0531	amino acid
CFH90_03840	COG1674	ftsk spoiiie
CFH90_03855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFH90_03860	COG2894	cell division
CFH90_03865	COG0850	regulation of cytokinetic process
CFH90_03875	COG0204	Acyl-transferase
CFH90_03880	COG2885	chlorophyll binding
CFH90_03885	COG0210	DNA helicase
CFH90_03890	COG0756	dUTP diphosphatase activity
CFH90_03905	COG0121	glutamine amidotransferase
CFH90_03920	COG2914	Belongs to the UPF0125 (RnfH) family
CFH90_03925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_03930	COG0735	belongs to the Fur family
CFH90_03960	COG0420	3'-5' exonuclease activity
CFH90_03965	COG2203	Gaf domain
CFH90_03965	COG3706	GGDEF domain
CFH90_03965	COG4251	negative regulation of phosphorylation
CFH90_03965	COG5001	Diguanylate cyclase
CFH90_03975	COG1090	epimerase
CFH90_03990	COG2050	protein possibly involved in aromatic compounds catabolism
CFH90_03995	COG1566	PFAM secretion protein HlyD family protein
CFH90_04000	COG2814	Major facilitator Superfamily
CFH90_04005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFH90_04015	COG0582	viral genome integration into host DNA
CFH90_04035	COG3617	BRO family, N-terminal domain
CFH90_04065	COG0629	single-stranded DNA binding
CFH90_04095	COG0582	viral genome integration into host DNA
CFH90_04180	COG3177	Filamentation induced by cAMP protein fic
CFH90_04210	COG4221	oxidoreductase activity
CFH90_04215	COG0583	DNA-binding transcription factor activity
CFH90_04220	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFH90_04225	COG0604	alcohol dehydrogenase
CFH90_04225	COG3321	synthase
CFH90_04240	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFH90_04250	COG1979	alcohol dehydrogenase
CFH90_04260	COG1902	pentaerythritol trinitrate reductase activity
CFH90_04270	COG1309	transcriptional regulator
CFH90_04275	COG2130	NADP-dependent
CFH90_04305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_04315	COG1346	cytolysis
CFH90_04325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFH90_04335	COG1294	oxidase, subunit
CFH90_04340	COG1271	oxidase subunit
CFH90_04365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFH90_04370	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_04385	COG3138	arginine N-succinyltransferase
CFH90_04390	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_04395	COG3724	N-succinylarginine dihydrolase activity
CFH90_04405	COG1113	amino acid transport
CFH90_04415	COG1414	Transcriptional regulator
CFH90_04420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_04425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_04430	COG0183	Belongs to the thiolase family
CFH90_04435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFH90_04440	COG0596	Alpha beta hydrolase
CFH90_04445	COG2271	Major facilitator Superfamily
CFH90_04450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFH90_04455	COG3485	protocatechuate 3,4-dioxygenase
CFH90_04460	COG3485	protocatechuate 3,4-dioxygenase
CFH90_04465	COG0710	3-dehydroquinate dehydratase activity
CFH90_04470	COG3420	alginic acid biosynthetic process
CFH90_04475	COG3659	wide pore channel activity
CFH90_04480	COG4993	Dehydrogenase
CFH90_04485	COG4772	TonB-dependent receptor
CFH90_04495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_04505	COG0583	DNA-binding transcription factor activity
CFH90_04510	COG2610	gluconate transmembrane transporter activity
CFH90_04515	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_04530	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFH90_04560	COG2801	Transposase and inactivated derivatives
CFH90_04575	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFH90_04585	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFH90_04590	COG1077	Cell shape determining protein MreB Mrl
CFH90_04595	COG1792	Involved in formation and maintenance of cell shape
CFH90_04600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CFH90_04605	COG0424	maF-like protein
CFH90_04610	COG1530	ribonuclease E activity
CFH90_04620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CFH90_04665	COG0640	Transcriptional regulator
CFH90_04675	COG0798	PFAM Bile acid sodium symporter
CFH90_04680	COG0431	NADPH-dependent FMN reductase
CFH90_04695	COG0625	glutathione transferase activity
CFH90_04715	COG1113	amino acid transport
CFH90_04740	COG1113	amino acid transport
CFH90_04745	COG2828	Protein conserved in bacteria
CFH90_04750	COG0142	geranyltranstransferase activity
CFH90_04765	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFH90_04785	COG2194	sulfuric ester hydrolase activity
CFH90_04790	COG0745	RESPONSE REGULATOR receiver
CFH90_04795	COG0642	Histidine kinase
CFH90_04810	COG0004	ammonium transporteR
CFH90_04820	COG1126	abc transporter atp-binding protein
CFH90_04825	COG0765	amino acid transport
CFH90_04830	COG0765	amino acid transport
CFH90_04850	COG0668	transmembrane transport
CFH90_04860	COG2081	HI0933 family
CFH90_04865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CFH90_04895	COG4716	Myosin-crossreactive antigen
CFH90_04920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_04930	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_04930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_04950	COG0489	protein tyrosine kinase activity
CFH90_05035	COG0840	transmembrane signaling receptor activity
CFH90_05040	COG0643	Histidine kinase
CFH90_05040	COG2198	Histidine kinase
CFH90_05040	COG0643	Histidine kinase
CFH90_05040	COG2198	Histidine kinase
CFH90_05050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFH90_05055	COG5510	response to toxic substance
CFH90_05065	COG2832	Protein of unknown function (DUF454)
CFH90_05075	COG3293	Transposase
CFH90_05140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFH90_05150	COG1289	transmembrane transporter activity
CFH90_05155	COG2814	Major facilitator Superfamily
CFH90_05170	COG0786	glutamate:sodium symporter activity
CFH90_05175	COG1115	amino acid carrier protein
CFH90_05185	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFH90_05195	COG1607	acyl-coa hydrolase
CFH90_05205	COG0523	cobalamin synthesis protein
CFH90_05210	COG4681	YaeQ
CFH90_05220	COG2203	Gaf domain
CFH90_05220	COG2199	diguanylate cyclase activity
CFH90_05275	COG0477	Major facilitator Superfamily
CFH90_05280	COG0242	peptide deformylase activity
CFH90_05285	COG2207	Transcriptional regulator
CFH90_05305	COG0306	phosphate transporter
CFH90_05330	COG4771	TonB-dependent receptor
CFH90_05355	COG4181	ATPase activity
CFH90_05360	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CFH90_05380	COG0583	DNA-binding transcription factor activity
CFH90_05390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_05395	COG1773	rubredoxin
CFH90_05400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFH90_05420	COG0175	sulfate reduction
CFH90_05480	COG0477	Major facilitator Superfamily
CFH90_05530	COG3209	COG3209 Rhs family protein
CFH90_05545	COG0641	radical SAM
CFH90_05550	COG3119	arylsulfatase activity
CFH90_05565	COG3335	DDE superfamily endonuclease
CFH90_05570	COG0204	Acyl-transferase
CFH90_05585	COG0742	ribosomal rna small subunit methyltransferase
CFH90_05590	COG0768	penicillin binding
CFH90_05615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFH90_05620	COG2878	Part of a membrane complex involved in electron transport
CFH90_05625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CFH90_05635	COG3384	dioxygenase
CFH90_05645	COG2234	aminopeptidase activity
CFH90_05660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFH90_05670	COG2217	Heavy metal translocating P-type atpase
CFH90_05675	COG0583	DNA-binding transcription factor activity
CFH90_05680	COG1914	H( )-stimulated, divalent metal cation uptake system
CFH90_05700	COG4770	biotin carboxylase activity
CFH90_05725	COG0006	proline dipeptidase activity
CFH90_05735	COG2801	Transposase and inactivated derivatives
CFH90_05835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFH90_05840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFH90_05860	COG2915	High frequency lysogenization protein hflD homolog
CFH90_05880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFH90_05885	COG1686	Belongs to the peptidase S11 family
CFH90_05920	COG0753	catalase activity
CFH90_05935	COG1388	LysM domain
CFH90_05935	COG4942	peptidase
CFH90_05940	COG0583	DNA-binding transcription factor activity
CFH90_05965	COG2816	NAD+ diphosphatase activity
CFH90_05975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFH90_05980	COG0741	lytic transglycosylase activity
CFH90_05980	COG1388	LysM domain
CFH90_05985	COG4166	transmembrane transport
CFH90_05990	COG4174	ABC transporter (Permease)
CFH90_05995	COG4239	(ABC) transporter, permease
CFH90_06000	COG4172	Belongs to the ABC transporter superfamily
CFH90_06015	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CFH90_06040	COG0833	amino acid
CFH90_06075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CFH90_06080	COG0418	dihydroorotase activity
CFH90_06085	COG4251	negative regulation of phosphorylation
CFH90_06085	COG5001	Diguanylate cyclase
CFH90_06085	COG2203	Gaf domain
CFH90_06085	COG3706	GGDEF domain
CFH90_06100	COG2186	Transcriptional regulator
CFH90_06110	COG0277	FAD linked oxidase domain protein
CFH90_06115	COG1902	pentaerythritol trinitrate reductase activity
CFH90_06115	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFH90_06145	COG0281	malic enzyme
CFH90_06145	COG0280	phosphate acetyltransferase
CFH90_06155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CFH90_06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CFH90_06165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFH90_06205	COG1960	acyl-CoA dehydrogenase activity
CFH90_06210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFH90_06215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_06225	COG1671	Belongs to the UPF0178 family
CFH90_06240	COG4591	ABC-type transport system involved in lipoprotein release permease component
CFH90_06245	COG1136	(ABC) transporter
CFH90_06250	COG2333	competence protein COMEC
CFH90_06250	COG0658	competence protein
CFH90_06270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFH90_06275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFH90_06280	COG0628	permease
CFH90_06315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFH90_06335	COG0823	Involved in the tonB-independent uptake of proteins
CFH90_06355	COG0824	Thioesterase
CFH90_06370	COG2255	four-way junction helicase activity
CFH90_06375	COG0632	four-way junction helicase activity
CFH90_06390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFH90_06390	COG0047	phosphoribosylformylglycinamidine synthase activity
CFH90_06400	COG3323	Protein of unknown function (DUF1653)
CFH90_06400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFH90_06415	COG0778	Nitroreductase
CFH90_06420	COG1024	Enoyl-CoA hydratase
CFH90_06425	COG1056	cytidyltransferase-related domain
CFH90_06425	COG1051	belongs to the nudix hydrolase family
CFH90_06430	COG2353	YceI-like domain
CFH90_06435	COG0583	DNA-binding transcription factor activity
CFH90_06445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFH90_06460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFH90_06465	COG0602	queuosine metabolic process
CFH90_06485	COG0583	DNA-binding transcription factor activity
CFH90_06490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFH90_06495	COG4208	sulfate ABC transporter
CFH90_06510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFH90_06520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFH90_06540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFH90_06545	COG3385	transposase activity
CFH90_06560	COG0681	Belongs to the peptidase S26 family
CFH90_06575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFH90_06585	COG1381	Involved in DNA repair and RecF pathway recombination
CFH90_06590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFH90_06655	COG0556	nucleotide-excision repair
CFH90_06695	COG0702	epimerase
CFH90_06700	COG1733	regulation of RNA biosynthetic process
CFH90_06710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFH90_06715	COG0671	phosphoesterase, PA-phosphatase related
CFH90_06720	COG4772	TonB-dependent receptor
CFH90_06730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFH90_06735	COG0076	glutamate decarboxylase activity
CFH90_06740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFH90_06745	COG0573	inorganic phosphate transmembrane transporter activity
CFH90_06755	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFH90_06760	COG0616	signal peptide processing
CFH90_06765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFH90_06770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFH90_06775	COG1067	ATP-dependent peptidase activity
CFH90_06795	COG0254	rRNA binding
CFH90_06815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFH90_06820	COG1966	Carbon starvation protein
CFH90_06825	COG2879	small protein
CFH90_06835	COG0714	Associated with various cellular activities
CFH90_06910	COG4372	Transposase
CFH90_06950	COG3046	protein related to deoxyribodipyrimidine photolyase
CFH90_06955	COG2816	NAD+ diphosphatase activity
CFH90_06980	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFH90_06995	COG0642	Histidine kinase
CFH90_07000	COG0745	RESPONSE REGULATOR receiver
CFH90_07035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFH90_07045	COG0783	Belongs to the Dps family
CFH90_07095	COG1131	(ABC) transporter
CFH90_07100	COG0842	Transport permease protein
CFH90_07105	COG0842	Transport permease protein
CFH90_07130	COG1309	transcriptional regulator
CFH90_07180	COG4372	Transposase
CFH90_07220	COG1733	regulation of RNA biosynthetic process
CFH90_07265	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFH90_07270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFH90_07285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFH90_07295	COG0133	tryptophan synthase activity
CFH90_07300	COG0516	GMP reductase activity
CFH90_07300	COG0517	IMP dehydrogenase activity
CFH90_07330	COG0612	Peptidase, M16
CFH90_07335	COG0552	protein localization to endoplasmic reticulum
CFH90_07340	COG3293	Transposase
CFH90_07370	COG2175	clavaminate synthase activity
CFH90_07375	COG3246	L-lysine catabolic process to acetate
CFH90_07395	COG2855	membrane
CFH90_07425	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_07435	COG0372	Belongs to the citrate synthase family
CFH90_07465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFH90_07470	COG0730	response to heat
CFH90_07495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_07500	COG1944	ATP diphosphatase activity
CFH90_07505	COG2207	Transcriptional regulator
CFH90_07510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFH90_07515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFH90_07545	COG2223	nitrite transmembrane transporter activity
CFH90_07560	COG1346	cytolysis
CFH90_07565	COG1380	Effector of murein hydrolase LrgA
CFH90_07570	COG0583	DNA-binding transcription factor activity
CFH90_07575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFH90_07605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFH90_07655	COG3123	guanosine phosphorylase activity
CFH90_07675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFH90_07680	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFH90_07695	COG3300	MHYT domain
CFH90_07695	COG5001	Diguanylate cyclase
CFH90_07700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFH90_07710	COG2814	Major facilitator Superfamily
CFH90_07725	COG1132	(ABC) transporter
CFH90_07735	COG0668	transmembrane transport
CFH90_07740	COG3122	Protein conserved in bacteria
CFH90_07760	COG0640	Transcriptional regulator
CFH90_07765	COG0596	Alpha beta hydrolase
CFH90_07770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_07775	COG1335	isochorismatase
CFH90_07780	COG0251	oxidation-reduction process
CFH90_07785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_07790	COG2233	PERMEase
CFH90_07800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFH90_07825	COG0183	Belongs to the thiolase family
CFH90_07830	COG0583	DNA-binding transcription factor activity
CFH90_07845	COG0439	Biotin carboxylase
CFH90_07860	COG0511	ligase activity, forming carbon-carbon bonds
CFH90_07870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_07875	COG0183	Belongs to the thiolase family
CFH90_07880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_07885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_07890	COG3135	benzoate transporter
CFH90_07895	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_07900	COG0633	Ferredoxin
CFH90_07900	COG0543	2 iron, 2 sulfur cluster binding
CFH90_07905	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CFH90_07910	COG4638	Rieske (2fe-2S)
CFH90_07920	COG4829	muconolactone delta-isomerase
CFH90_07925	COG4948	Mandelate Racemase Muconate Lactonizing
CFH90_07930	COG0583	DNA-binding transcription factor activity
CFH90_07935	COG2814	Major facilitator Superfamily
CFH90_08110	COG2814	Major facilitator Superfamily
CFH90_08135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFH90_08140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFH90_08145	COG0022	dehydrogenase e1 component
CFH90_08150	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFH90_08155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_08165	COG1063	alcohol dehydrogenase
CFH90_08170	COG4628	conserved protein (DUF2132)
CFH90_08195	COG0656	L-ascorbic acid biosynthetic process
CFH90_08200	COG1073	alpha beta
CFH90_08215	COG1064	alcohol dehydrogenase
CFH90_08235	COG2814	Major facilitator Superfamily
CFH90_08335	COG2801	Transposase and inactivated derivatives
CFH90_08350	COG1230	cation diffusion facilitator family transporter
CFH90_08355	COG0730	response to heat
CFH90_08360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_08475	COG0300	oxidoreductase activity
CFH90_08485	COG1022	Amp-dependent synthetase and ligase
CFH90_08495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFH90_08500	COG0842	Transport permease protein
CFH90_08505	COG1129	ABC transporter
CFH90_08505	COG0842	Transport permease protein
CFH90_08510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_08545	COG0745	RESPONSE REGULATOR receiver
CFH90_08550	COG0642	Histidine kinase
CFH90_08565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFH90_08595	COG0640	Transcriptional regulator
CFH90_08650	COG0596	Alpha beta hydrolase
CFH90_08720	COG0864	Transcriptional regulator
CFH90_08750	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_08755	COG2814	Major facilitator Superfamily
CFH90_08765	COG2199	diguanylate cyclase activity
CFH90_08810	COG1960	acyl-CoA dehydrogenase activity
CFH90_08815	COG1960	acyl-CoA dehydrogenase activity
CFH90_08870	COG3293	Transposase
CFH90_08915	COG1464	Belongs to the NlpA lipoprotein family
CFH90_08920	COG1464	Belongs to the NlpA lipoprotein family
CFH90_08925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFH90_08930	COG2011	ABC-type metal ion transport system permease component
CFH90_08940	COG0012	GTP binding
CFH90_08965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFH90_08980	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFH90_09015	COG0386	Belongs to the glutathione peroxidase family
CFH90_09020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFH90_09025	COG0436	Aminotransferase
CFH90_09060	COG3634	alkyl hydroperoxide reductase activity
CFH90_09085	COG2070	2-Nitropropane dioxygenase
CFH90_09120	COG0537	adenosine 5'-monophosphoramidase activity
CFH90_09145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_09150	COG0776	regulation of translation
CFH90_09165	COG1959	2 iron, 2 sulfur cluster binding
CFH90_09175	COG0822	iron-sulfur transferase activity
CFH90_09180	COG0316	Belongs to the HesB IscA family
CFH90_09210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFH90_09225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFH90_09235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFH90_09235	COG0506	proline dehydrogenase activity
CFH90_09235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CFH90_09270	COG3781	membrane
CFH90_09275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_09285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_09305	COG0697	spore germination
CFH90_09320	COG0126	phosphoglycerate kinase activity
CFH90_09330	COG0424	maF-like protein
CFH90_09340	COG2850	peptidyl-arginine hydroxylation
CFH90_09345	COG4585	Histidine kinase
CFH90_09350	COG2197	response regulator
CFH90_09355	COG0069	glutamate synthase activity
CFH90_09375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFH90_09380	COG1454	alcohol dehydrogenase
CFH90_09385	COG0824	Thioesterase
CFH90_09390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFH90_09410	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_09415	COG0183	Belongs to the thiolase family
CFH90_09430	COG0583	DNA-binding transcription factor activity
CFH90_09435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFH90_09445	COG3135	benzoate transporter
CFH90_09450	COG1309	transcriptional regulator
CFH90_09455	COG2076	Multidrug Resistance protein
CFH90_09470	COG0589	response to stress
CFH90_09480	COG0308	aminopeptidase N
CFH90_09505	COG1253	flavin adenine dinucleotide binding
CFH90_09525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFH90_09530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFH90_09545	COG2431	L-lysine efflux transmembrane transporter activity
CFH90_09560	COG0776	regulation of translation
CFH90_09580	COG0590	tRNA wobble adenosine to inosine editing
CFH90_09590	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFH90_09625	COG0084	hydrolase, TatD family'
CFH90_09645	COG1663	tetraacyldisaccharide 4'-kinase activity
CFH90_09650	COG1132	(ABC) transporter
CFH90_09660	COG0811	peptide transport
CFH90_09665	COG1475	DNA binding
CFH90_09670	COG1192	Involved in chromosome partitioning
CFH90_09680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFH90_09685	COG3178	'Phosphotransferase
CFH90_09695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_09700	COG1923	regulation of RNA biosynthetic process
CFH90_09710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFH90_09715	COG0802	atpase or kinase
CFH90_09735	COG1187	pseudouridine synthase activity
CFH90_09740	COG2707	UPF0756 membrane protein
CFH90_09745	COG2814	Major facilitator Superfamily
CFH90_09750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFH90_09755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFH90_09765	COG1454	alcohol dehydrogenase
CFH90_09790	COG4303	Ethanolamine ammonia lyase large subunit
CFH90_09805	COG4302	ethanolamine ammonia-lyase activity
CFH90_09815	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_09825	COG0519	Catalyzes the synthesis of GMP from XMP
CFH90_09825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFH90_09845	COG2353	YceI-like domain
CFH90_09860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFH90_09865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFH90_09920	COG0352	thiamine-phosphate diphosphorylase activity
CFH90_09925	COG3293	Transposase
CFH90_09960	COG0612	Peptidase, M16
CFH90_09975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_10015	COG2351	hydroxyisourate hydrolase activity
CFH90_10025	COG1686	Belongs to the peptidase S11 family
CFH90_10030	COG1252	NADH dehydrogenase
CFH90_10035	COG1047	Peptidyl-prolyl cis-trans
CFH90_10045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFH90_10045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFH90_10070	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_10075	COG2819	hydrolase of the alpha beta superfamily
CFH90_10090	COG0372	Belongs to the citrate synthase family
CFH90_10120	COG0542	response to heat
CFH90_10125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFH90_10145	COG3293	Transposase
CFH90_10155	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFH90_10160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFH90_10170	COG0569	domain protein
CFH90_10175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFH90_10195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFH90_10205	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFH90_10220	COG1294	oxidase, subunit
CFH90_10225	COG4890	Cyd operon protein YbgT
CFH90_10240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CFH90_10245	COG1309	transcriptional regulator
CFH90_10250	COG1012	belongs to the aldehyde dehydrogenase family
CFH90_10260	COG0579	oxidoreductase
CFH90_10275	COG0772	Belongs to the SEDS family
CFH90_10290	COG0148	phosphopyruvate hydratase activity
CFH90_10310	COG0583	DNA-binding transcription factor activity
CFH90_10320	COG2814	Major facilitator Superfamily
CFH90_10335	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFH90_10335	COG1902	pentaerythritol trinitrate reductase activity
CFH90_10345	COG2267	carboxylic ester hydrolase activity
CFH90_10355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFH90_10360	COG0702	epimerase
CFH90_10390	COG3293	Transposase
CFH90_10400	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFH90_10415	COG1011	Hydrolase
CFH90_10420	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CFH90_10425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFH90_10430	COG2137	regulation of response to DNA damage stimulus
CFH90_10455	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFH90_10475	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFH90_10490	COG0575	Belongs to the CDS family
CFH90_10495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFH90_10515	COG3852	Histidine kinase
CFH90_10530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_10535	COG0583	DNA-binding transcription factor activity
CFH90_10540	COG0024	Methionine aminopeptidase
CFH90_10565	COG1113	amino acid transport
CFH90_10575	COG0786	glutamate:sodium symporter activity
CFH90_10580	COG4773	Receptor
CFH90_10635	COG0729	surface antigen
CFH90_10660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFH90_10675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFH90_10680	COG1960	acyl-CoA dehydrogenase activity
CFH90_10710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_10715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFH90_10720	COG2890	protein-(glutamine-N5) methyltransferase activity
CFH90_10725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFH90_10740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_10770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFH90_10775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFH90_10780	COG1845	cytochrome c oxidase, subunit III
CFH90_10785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFH90_10805	COG0360	Binds together with S18 to 16S ribosomal RNA
CFH90_10820	COG0305	Participates in initiation and elongation during chromosome replication
CFH90_10825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFH90_10840	COG1305	Transglutaminase-like
CFH90_10850	COG2308	Evidence 4 Homologs of previously reported genes of
CFH90_10865	COG0445	tRNA wobble uridine modification
CFH90_10895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CFH90_10900	COG0138	bifunctional purine biosynthesis protein purh
CFH90_10905	COG0151	Belongs to the GarS family
CFH90_10920	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFH90_10940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFH90_10945	COG2011	ABC-type metal ion transport system permease component
CFH90_10985	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CFH90_11015	COG1137	ATPase activity
CFH90_11020	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFH90_11030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CFH90_11035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CFH90_11035	COG0517	IMP dehydrogenase activity
CFH90_11045	COG0406	alpha-ribazole phosphatase activity
CFH90_11050	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFH90_11085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFH90_11095	COG0243	molybdopterin cofactor binding
CFH90_11100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_11105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_11110	COG2223	nitrite transmembrane transporter activity
CFH90_11120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_11120	COG1116	anion transmembrane transporter activity
CFH90_11140	COG1643	Atp-dependent helicase
CFH90_11145	COG0450	alkyl hydroperoxide reductase
CFH90_11150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_11190	COG0515	serine threonine protein kinase
CFH90_11190	COG2815	serine threonine protein kinase
CFH90_11215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFH90_11220	COG1610	YqeY-like protein
CFH90_11225	COG4783	chaperone-mediated protein folding
CFH90_11280	COG0778	Nitroreductase
CFH90_11290	COG0513	Belongs to the DEAD box helicase family
CFH90_11295	COG1278	Cold shock
CFH90_11310	COG2363	Small membrane protein
CFH90_11330	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CFH90_11335	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFH90_11340	COG0625	glutathione transferase activity
CFH90_11345	COG0659	secondary active sulfate transmembrane transporter activity
CFH90_11355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFH90_11385	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_11390	COG1309	transcriptional regulator
CFH90_11395	COG1960	acyl-CoA dehydrogenase activity
CFH90_11400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFH90_11425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_11430	COG2031	fatty acid transporter
CFH90_11450	COG0540	Belongs to the ATCase OTCase family
CFH90_11475	COG1765	OsmC-like protein
CFH90_11485	COG0667	Aldo Keto reductase
CFH90_11500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFH90_11515	COG1522	sequence-specific DNA binding
CFH90_11520	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFH90_11535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CFH90_11545	COG0527	aspartate kinase activity
CFH90_11555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFH90_11570	COG3038	cytochrome b561
CFH90_11580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFH90_11585	COG2252	PERMEase
CFH90_11595	COG0415	Belongs to the DNA photolyase family
CFH90_11625	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFH90_11630	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFH90_11640	COG0693	protein deglycase activity
CFH90_11645	COG1960	acyl-CoA dehydrogenase activity
CFH90_11650	COG1301	dicarboxylic acid transport
CFH90_11665	COG3139	Protein of unknown function (DUF1315)
CFH90_11670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFH90_11675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFH90_11685	COG0494	nUDIX hydrolase
CFH90_11695	COG0642	Histidine kinase
CFH90_11700	COG0745	RESPONSE REGULATOR receiver
CFH90_11710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFH90_11720	COG1720	tRNA m6t6A37 methyltransferase activity
CFH90_11760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFH90_11765	COG3634	alkyl hydroperoxide reductase activity
CFH90_11790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFH90_11845	COG0235	Class ii aldolase
CFH90_11850	COG2169	Transcriptional regulator
CFH90_11870	COG4149	molybdate abc transporter
CFH90_11875	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFH90_11885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFH90_11900	COG0315	cyclic pyranopterin monophosphate synthase activity
CFH90_11900	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFH90_11905	COG0303	'Molybdopterin
CFH90_11925	COG3177	Filamentation induced by cAMP protein fic
CFH90_11930	COG0583	DNA-binding transcription factor activity
CFH90_11935	COG1960	acyl-CoA dehydrogenase activity
CFH90_11940	COG2301	Belongs to the HpcH HpaI aldolase family
CFH90_11945	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CFH90_11955	COG0583	DNA-binding transcription factor activity
CFH90_11965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_11980	COG4829	muconolactone delta-isomerase
CFH90_11985	COG0427	acetyl-CoA hydrolase
CFH90_11990	COG0183	Belongs to the thiolase family
CFH90_12025	COG3586	endonuclease activity
CFH90_12050	COG2184	nucleotidyltransferase activity
CFH90_12085	COG0582	viral genome integration into host DNA
CFH90_12095	COG1131	(ABC) transporter
CFH90_12100	COG0842	Transport permease protein
CFH90_12115	COG2951	lytic endotransglycosylase activity
CFH90_12160	COG0052	Belongs to the universal ribosomal protein uS2 family
CFH90_12165	COG0024	Methionine aminopeptidase
CFH90_12180	COG2175	clavaminate synthase activity
CFH90_12195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_12200	COG0842	Transport permease protein
CFH90_12235	COG1280	lysine exporter protein (LysE YggA)
CFH90_12240	COG1522	sequence-specific DNA binding
CFH90_12245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFH90_12255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CFH90_12265	COG0019	diaminopimelate decarboxylase activity
CFH90_12275	COG1113	amino acid transport
CFH90_12285	COG1115	amino acid carrier protein
CFH90_12300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFH90_12305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFH90_12315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFH90_12355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CFH90_12360	COG3161	chorismate lyase activity
CFH90_12375	COG0512	Glutamine amidotransferase of anthranilate synthase
CFH90_12380	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFH90_12385	COG0134	indole-3-glycerol-phosphate synthase activity
CFH90_12405	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_12420	COG0302	gtp cyclohydrolase
CFH90_12430	COG3706	GGDEF domain
CFH90_12445	COG3739	integral membrane protein
CFH90_12465	COG1741	Belongs to the pirin family
CFH90_12480	COG1309	transcriptional regulator
CFH90_12515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFH90_12520	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CFH90_12530	COG0037	tRNA processing
CFH90_12535	COG0741	lytic transglycosylase activity
CFH90_12540	COG0501	Belongs to the peptidase M48B family
CFH90_12555	COG2239	Acts as a magnesium transporter
CFH90_12585	COG1253	flavin adenine dinucleotide binding
CFH90_12590	COG2851	Citrate transporter
CFH90_12630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFH90_12635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFH90_12660	COG0505	Belongs to the CarA family
CFH90_12665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFH90_12705	COG3695	enzyme binding
CFH90_12720	COG2321	neutral zinc metallopeptidase
CFH90_12725	COG2354	Protein conserved in bacteria
CFH90_12735	COG1585	Membrane protein implicated in regulation of membrane protease activity
CFH90_12740	COG2268	Band 7 protein
CFH90_12750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFH90_12760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFH90_12775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CFH90_12780	COG1053	succinate dehydrogenase
CFH90_12785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CFH90_12790	COG2009	succinate dehydrogenase
CFH90_12820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CFH90_12820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFH90_12845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CFH90_12870	COG0564	pseudouridine synthase activity
CFH90_12880	COG0358	DNA primase activity
CFH90_12895	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CFH90_12925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFH90_12930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFH90_12990	COG0586	Pfam SNARE associated Golgi protein
CFH90_13025	COG2921	Belongs to the UPF0250 family
CFH90_13030	COG0321	lipoyl(octanoyl) transferase activity
CFH90_13045	COG0531	amino acid
CFH90_13065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFH90_13070	COG1648	precorrin-2 dehydrogenase activity
CFH90_13070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFH90_13075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFH90_13085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFH90_13095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFH90_13115	COG0671	phosphoesterase, PA-phosphatase related
CFH90_13120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFH90_13130	COG1538	Outer membrane efflux protein
CFH90_13135	COG0393	Putative heavy-metal-binding
CFH90_13150	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_13160	COG0525	valine-tRNA ligase activity
CFH90_13190	COG0583	DNA-binding transcription factor activity
CFH90_13200	COG1278	Cold shock
CFH90_13205	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFH90_13215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_13220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFH90_13225	COG0713	ATP synthesis coupled electron transport
CFH90_13235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_13250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFH90_13270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFH90_13280	COG2205	protein histidine kinase activity
CFH90_13285	COG0745	RESPONSE REGULATOR receiver
CFH90_13295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFH90_13330	COG3209	COG3209 Rhs family protein
CFH90_13350	COG0439	Biotin carboxylase
CFH90_13355	COG1802	Transcriptional regulator
CFH90_13360	COG1652	LysM domain
CFH90_13370	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_13380	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFH90_13385	COG1399	metal-binding, possibly nucleic acid-binding protein
CFH90_13390	COG3101	peptidyl-lysine hydroxylation
CFH90_13395	COG0009	L-threonylcarbamoyladenylate synthase
CFH90_13410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFH90_13415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFH90_13465	COG4106	trans-aconitate 2-methyltransferase activity
CFH90_13480	COG2226	methyltransferase
CFH90_13480	COG0596	Alpha beta hydrolase
CFH90_13480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_13490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFH90_13495	COG2193	ferroxidase activity
CFH90_13510	COG4774	siderophore transport
CFH90_13515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFH90_13520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFH90_13525	COG3115	cell septum assembly
CFH90_13530	COG1196	nuclear chromosome segregation
CFH90_13540	COG0730	response to heat
CFH90_13560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFH90_13615	COG3422	double-strand break repair
CFH90_13625	COG2824	Alkylphosphonate utilization operon protein PhnA
CFH90_13630	COG3189	MarR family transcriptional regulator
CFH90_13650	COG0564	pseudouridine synthase activity
CFH90_13655	COG0346	lactoylglutathione lyase activity
CFH90_13695	COG4456	Virulence-associated protein
CFH90_13715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFH90_13745	COG1902	pentaerythritol trinitrate reductase activity
CFH90_13760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFH90_13770	COG1970	mechanosensitive ion channel activity
CFH90_13780	COG2233	PERMEase
CFH90_13785	COG2813	Specifically methylates the guanine in position
CFH90_13790	COG0833	amino acid
CFH90_13795	COG2885	chlorophyll binding
CFH90_13795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CFH90_13805	COG0183	Belongs to the thiolase family
CFH90_13825	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFH90_13840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFH90_13845	COG2207	Transcriptional regulator
CFH90_13850	COG0183	Belongs to the thiolase family
CFH90_13855	COG1024	Enoyl-CoA hydratase
CFH90_13855	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFH90_13875	COG1272	protein, Hemolysin III
CFH90_13880	COG0477	Major facilitator Superfamily
CFH90_13890	COG1408	metallophosphoesterase
CFH90_13895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFH90_13905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFH90_13930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CFH90_13935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFH90_13955	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFH90_13960	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFH90_13965	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFH90_13975	COG0625	glutathione transferase activity
CFH90_13980	COG2969	positive regulation of protein catabolic process
CFH90_13995	COG3293	Transposase
CFH90_14045	COG2853	Lipoprotein
CFH90_14050	COG2208	phosphoserine phosphatase activity
CFH90_14060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFH90_14065	COG1764	response to oxidative stress
CFH90_14095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFH90_14095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFH90_14110	COG0037	tRNA processing
CFH90_14145	COG0072	phenylalanine-tRNA ligase activity
CFH90_14170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFH90_14190	COG1238	metal cluster binding
CFH90_14200	COG0625	glutathione transferase activity
CFH90_14220	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_14225	COG3028	Belongs to the UPF0307 family
CFH90_14235	COG1660	Displays ATPase and GTPase activities
CFH90_14240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFH90_14250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFH90_14255	COG0617	tRNA 3'-terminal CCA addition
CFH90_14260	COG1555	photosystem II stabilization
CFH90_14265	COG3956	TIGRFAM MazG family protein
CFH90_14275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFH90_14290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFH90_14295	COG0784	Response regulator, receiver
CFH90_14295	COG2205	protein histidine kinase activity
CFH90_14295	COG5002	protein histidine kinase activity
CFH90_14300	COG1024	Enoyl-CoA hydratase
CFH90_14305	COG2084	Dehydrogenase
CFH90_14310	COG3622	Belongs to the hyi family
CFH90_14325	COG0004	ammonium transporteR
CFH90_14335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFH90_14340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFH90_14345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CFH90_14350	COG2814	Major facilitator Superfamily
CFH90_14365	COG4638	Rieske (2fe-2S)
CFH90_14370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CFH90_14375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFH90_14375	COG0543	2 iron, 2 sulfur cluster binding
CFH90_14385	COG3385	transposase activity
CFH90_14420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFH90_14430	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_14465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CFH90_14480	COG0732	type I restriction modification DNA specificity domain
CFH90_14490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CFH90_14760	COG3620	sequence-specific DNA binding
CFH90_14815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFH90_14830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CFH90_14840	COG0084	hydrolase, TatD family'
CFH90_14855	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFH90_14870	COG0793	Belongs to the peptidase S41A family
CFH90_14895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFH90_14900	COG0857	belongs to the CobB CobQ family
CFH90_14900	COG0280	phosphate acetyltransferase
CFH90_14910	COG2318	DinB family
CFH90_14920	COG2207	Transcriptional regulator
CFH90_14920	COG1917	Cupin 2, conserved barrel domain protein
CFH90_14930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CFH90_14930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CFH90_14950	COG0740	serine-type endopeptidase activity
CFH90_14960	COG4771	TonB-dependent receptor
CFH90_14965	COG4774	siderophore transport
CFH90_14980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFH90_14990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_14990	COG2813	Specifically methylates the guanine in position
CFH90_15095	COG0788	formyltetrahydrofolate deformylase activity
CFH90_15110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFH90_15115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFH90_15120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFH90_15120	COG4651	solute:proton antiporter activity
CFH90_15140	COG0210	DNA helicase
CFH90_15145	COG1929	Belongs to the glycerate kinase type-1 family
CFH90_15185	COG2900	Belongs to the SlyX family
CFH90_15200	COG1560	Kdo2-lipid A biosynthetic process
CFH90_15240	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFH90_15255	COG0473	3-isopropylmalate dehydrogenase activity
CFH90_15270	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFH90_15280	COG0583	DNA-binding transcription factor activity
CFH90_15315	COG1280	lysine exporter protein (LysE YggA)
CFH90_15330	COG1960	acyl-CoA dehydrogenase activity
CFH90_15365	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFH90_15380	COG0583	DNA-binding transcription factor activity
CFH90_15395	COG0564	pseudouridine synthase activity
CFH90_15405	COG1530	ribonuclease E activity
CFH90_15410	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_15435	COG1983	PspC domain protein
CFH90_15460	COG0751	glycine-tRNA ligase activity
CFH90_15495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFH90_15510	COG2226	methyltransferase
CFH90_15535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFH90_15545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFH90_15550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFH90_15560	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFH90_15570	COG0644	oxidoreductase
CFH90_15570	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CFH90_15580	COG0425	Belongs to the sulfur carrier protein TusA family
CFH90_15585	COG4535	Mg2 and Co2 transporter CorC
CFH90_15590	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFH90_15595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFH90_15615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFH90_15625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFH90_15645	COG2841	Protein conserved in bacteria
CFH90_15650	COG0598	Magnesium transport protein CorA
CFH90_15655	COG1185	polyribonucleotide nucleotidyltransferase activity
CFH90_15670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFH90_15675	COG1074	ATP-dependent DNA helicase activity
CFH90_15680	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CFH90_15710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFH90_15725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFH90_15735	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFH90_15740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFH90_15740	COG2111	Na H antiporter
CFH90_15745	COG1006	Multisubunit Na H antiporter MnhC subunit
CFH90_15750	COG0651	ATP synthesis coupled electron transport
CFH90_15760	COG2212	antiporter activity
CFH90_15770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFH90_15780	COG0195	Participates in both transcription termination and antitermination
CFH90_15840	COG0237	dephospho-CoA kinase activity
CFH90_15850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFH90_15855	COG3123	guanosine phosphorylase activity
CFH90_15860	COG0497	DNA recombination
CFH90_15865	COG1678	Uncharacterized ACR, COG1678
CFH90_15870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFH90_15885	COG1289	transmembrane transporter activity
CFH90_15900	COG1132	(ABC) transporter
CFH90_15905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFH90_15975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CFH90_16000	COG0326	Molecular chaperone. Has ATPase activity
CFH90_16010	COG3047	cAMP biosynthetic process
CFH90_16015	COG2056	Na+-H+ antiporter family
CFH90_16040	COG3385	transposase activity
CFH90_16045	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFH90_16050	COG0085	RNA polymerase activity
CFH90_16055	COG0222	ribosome binding
CFH90_16060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFH90_16065	COG0081	regulation of translation
CFH90_16070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFH90_16090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFH90_16120	COG0546	phosphoglycolate phosphatase activity
CFH90_16150	COG0824	Thioesterase
CFH90_16170	COG0181	hydroxymethylbilane synthase activity
CFH90_16180	COG3275	phosphorelay sensor kinase activity
CFH90_16200	COG1538	Outer membrane efflux protein
CFH90_16210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFH90_16220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CFH90_16225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFH90_16230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFH90_16235	COG0772	Belongs to the SEDS family
CFH90_16240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFH90_16260	COG4974	Belongs to the 'phage' integrase family
CFH90_16265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_16275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFH90_16285	COG2197	response regulator
CFH90_16300	COG0793	Belongs to the peptidase S41A family
CFH90_16305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFH90_16310	COG0795	lipopolysaccharide-transporting ATPase activity
CFH90_16315	COG0795	lipopolysaccharide-transporting ATPase activity
CFH90_16335	COG0586	Pfam SNARE associated Golgi protein
CFH90_16350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFH90_16350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFH90_16360	COG0004	ammonium transporteR
CFH90_16365	COG0347	Belongs to the P(II) protein family
CFH90_16375	COG0606	chelatase, subunit chli
CFH90_16395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFH90_16410	COG0318	PFAM AMP-dependent synthetase and ligase
CFH90_16425	COG0477	Major facilitator Superfamily
CFH90_16430	COG2860	membrane
CFH90_16435	COG3012	SEC-C Motif Domain Protein
CFH90_16440	COG1253	flavin adenine dinucleotide binding
CFH90_16460	COG2814	Major facilitator Superfamily
CFH90_16470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFH90_16550	COG0758	DNA mediated transformation
CFH90_16560	COG0697	spore germination
CFH90_16570	COG0386	Belongs to the glutathione peroxidase family
CFH90_16605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFH90_16615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFH90_16655	COG1121	(ABC) transporter
CFH90_16660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFH90_16665	COG1683	Conserved Protein
CFH90_16675	COG2837	iron assimilation
CFH90_16700	COG0791	NLP P60 protein
CFH90_16700	COG1388	LysM domain
CFH90_16705	COG3501	Rhs element vgr protein
CFH90_16710	COG0281	malic enzyme
CFH90_16765	COG0519	Catalyzes the synthesis of GMP from XMP
CFH90_16765	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFH90_16770	COG3111	PFAM Bacterial OB fold (BOF) protein
CFH90_16780	COG0586	Pfam SNARE associated Golgi protein
CFH90_16795	COG1192	Involved in chromosome partitioning
CFH90_16805	COG0271	Belongs to the BolA IbaG family
CFH90_16825	COG3655	Transcriptional regulator
CFH90_16850	COG1203	CRISPR-associated helicase, Cas3
CFH90_16960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFH90_16985	COG0640	Transcriptional regulator
CFH90_17005	COG0745	RESPONSE REGULATOR receiver
CFH90_17010	COG0642	Histidine kinase
CFH90_17035	COG3550	peptidyl-serine autophosphorylation
CFH90_17040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFH90_17080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CFH90_17095	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CFH90_17095	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFH90_17095	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CFH90_17100	COG1105	Belongs to the carbohydrate kinase PfkB family
CFH90_17105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFH90_17105	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFH90_17110	COG0583	DNA-binding transcription factor activity
CFH90_17115	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFH90_17130	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFH90_17140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFH90_17145	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CFH90_17155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFH90_17195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFH90_17200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFH90_17215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFH90_17225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFH90_17235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFH90_17240	COG0438	transferase activity, transferring glycosyl groups
CFH90_17250	COG0367	asparagine synthase
CFH90_17260	COG0438	transferase activity, transferring glycosyl groups
CFH90_17275	COG0110	maltose O-acetyltransferase activity
CFH90_17280	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_17285	COG1083	cytidylyl-transferase
CFH90_17290	COG0673	inositol 2-dehydrogenase activity
CFH90_17295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFH90_17305	COG2089	acid synthase
CFH90_17310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CFH90_17315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFH90_17325	COG2244	polysaccharide biosynthetic process
CFH90_17340	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFH90_17355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CFH90_17390	COG0728	peptidoglycan biosynthetic process
CFH90_17395	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFH90_17405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFH90_17415	COG3307	-O-antigen
CFH90_17420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_17425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFH90_17430	COG0546	phosphoglycolate phosphatase activity
CFH90_17435	COG1028	Short-chain dehydrogenase reductase Sdr
CFH90_17455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFH90_17455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CFH90_17460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_17465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFH90_17470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFH90_17475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFH90_17480	COG1116	anion transmembrane transporter activity
CFH90_17485	COG1309	transcriptional regulator
CFH90_17500	COG0196	riboflavin kinase activity
CFH90_17505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFH90_17510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFH90_17515	COG1047	Peptidyl-prolyl cis-trans
CFH90_17530	COG2133	pyrroloquinoline quinone binding
CFH90_17570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFH90_17575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFH90_17580	COG2951	lytic endotransglycosylase activity
CFH90_17585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFH90_17600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFH90_17620	COG0861	Integral membrane protein TerC family
CFH90_17640	COG0402	S-adenosylhomocysteine deaminase activity
CFH90_17655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFH90_17660	COG1230	cation diffusion facilitator family transporter
CFH90_17680	COG0706	membrane insertase activity
CFH90_17685	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFH90_17695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFH90_17745	COG0778	Nitroreductase
CFH90_17790	COG2871	sodium ion transport
CFH90_17835	COG0583	DNA-binding transcription factor activity
CFH90_17845	COG4680	protein conserved in bacteria
CFH90_17850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFH90_17855	COG0183	Belongs to the thiolase family
CFH90_17860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFH90_17865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFH90_17870	COG4829	muconolactone delta-isomerase
CFH90_17875	COG4948	Mandelate Racemase Muconate Lactonizing
CFH90_17880	COG0583	DNA-binding transcription factor activity
CFH90_17885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFH90_17890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFH90_17895	COG3485	protocatechuate 3,4-dioxygenase
CFH90_17945	COG0582	viral genome integration into host DNA
CFH90_18015	COG3971	2-oxopent-4-enoate hydratase activity
CFH90_18020	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CFH90_18025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFH90_18030	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFH90_18055	COG2801	Transposase and inactivated derivatives
CFH90_18090	COG0659	secondary active sulfate transmembrane transporter activity
CFH90_18095	COG2801	Transposase and inactivated derivatives
CFH90_18100	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CFH90_18135	COG0753	catalase activity
CFH90_18155	COG0477	Major facilitator Superfamily
CFH90_18175	COG1192	Involved in chromosome partitioning
CFH90_18180	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFH90_18185	COG1192	Involved in chromosome partitioning
CFH90_18230	COG0789	Transcriptional regulator
CFH90_18325	COG3077	Addiction module antitoxin, RelB DinJ family