locus-tag	class	description
KXJ74_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KXJ74_00010	COG0592	DNA-directed DNA polymerase activity
KXJ74_00020	COG0187	DNA topoisomerase II activity
KXJ74_00030	COG0488	(ABC) transporter
KXJ74_00080	COG0657	acetylesterase activity
KXJ74_00090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KXJ74_00120	COG2814	Major facilitator Superfamily
KXJ74_00135	COG0733	neurotransmitter:sodium symporter activity
KXJ74_00145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KXJ74_00165	COG0129	dihydroxy-acid dehydratase activity
KXJ74_00210	COG2233	PERMEase
KXJ74_00215	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KXJ74_00225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_00250	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KXJ74_00270	COG1064	alcohol dehydrogenase
KXJ74_00275	COG2818	Glycosylase
KXJ74_00325	COG1596	polysaccharide export
KXJ74_00330	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KXJ74_00345	COG0438	transferase activity, transferring glycosyl groups
KXJ74_00350	COG0438	transferase activity, transferring glycosyl groups
KXJ74_00355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KXJ74_00365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KXJ74_00380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KXJ74_00410	COG0438	transferase activity, transferring glycosyl groups
KXJ74_00425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KXJ74_00430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KXJ74_00445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ74_00450	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KXJ74_00455	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KXJ74_00465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KXJ74_00470	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KXJ74_00510	COG1454	alcohol dehydrogenase
KXJ74_00535	COG0477	Major facilitator Superfamily
KXJ74_00555	COG0271	Belongs to the BolA IbaG family
KXJ74_00565	COG1192	Involved in chromosome partitioning
KXJ74_00580	COG0586	Pfam SNARE associated Golgi protein
KXJ74_00585	COG2259	Doxx family
KXJ74_00595	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ74_00595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KXJ74_00610	COG3706	GGDEF domain
KXJ74_00675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ74_00680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ74_00690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ74_00695	COG0534	Mate efflux family protein
KXJ74_00725	COG2837	iron assimilation
KXJ74_00735	COG2318	DinB family
KXJ74_00740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KXJ74_00745	COG1121	(ABC) transporter
KXJ74_00785	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KXJ74_00795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KXJ74_00830	COG0386	Belongs to the glutathione peroxidase family
KXJ74_00840	COG0697	spore germination
KXJ74_00850	COG0758	DNA mediated transformation
KXJ74_00880	COG1309	transcriptional regulator
KXJ74_00935	COG4452	Inner membrane protein CreD
KXJ74_00940	COG2205	protein histidine kinase activity
KXJ74_00950	COG0745	RESPONSE REGULATOR receiver
KXJ74_00955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KXJ74_00970	COG2814	Major facilitator Superfamily
KXJ74_00985	COG1253	flavin adenine dinucleotide binding
KXJ74_00995	COG2860	membrane
KXJ74_01000	COG0477	Major facilitator Superfamily
KXJ74_01005	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KXJ74_01010	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ74_01025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KXJ74_01045	COG0606	chelatase, subunit chli
KXJ74_01080	COG0745	RESPONSE REGULATOR receiver
KXJ74_01085	COG5002	protein histidine kinase activity
KXJ74_01095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ74_01100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_01110	COG0606	chelatase, subunit chli
KXJ74_01120	COG0347	Belongs to the P(II) protein family
KXJ74_01125	COG0004	ammonium transporteR
KXJ74_01150	COG0586	Pfam SNARE associated Golgi protein
KXJ74_01175	COG0795	lipopolysaccharide-transporting ATPase activity
KXJ74_01180	COG0795	lipopolysaccharide-transporting ATPase activity
KXJ74_01190	COG0793	Belongs to the peptidase S41A family
KXJ74_01205	COG2197	response regulator
KXJ74_01210	COG1686	Belongs to the peptidase S11 family
KXJ74_01225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KXJ74_01240	COG4974	Belongs to the 'phage' integrase family
KXJ74_01265	COG0772	Belongs to the SEDS family
KXJ74_01270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ74_01275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KXJ74_01280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KXJ74_01285	COG0494	nUDIX hydrolase
KXJ74_01290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KXJ74_01310	COG1132	(ABC) transporter
KXJ74_01350	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KXJ74_01380	COG0497	DNA recombination
KXJ74_01385	COG3123	guanosine phosphorylase activity
KXJ74_01390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ74_01400	COG0237	dephospho-CoA kinase activity
KXJ74_01455	COG0779	Required for maturation of 30S ribosomal subunits
KXJ74_01460	COG0195	Participates in both transcription termination and antitermination
KXJ74_01465	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KXJ74_01470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KXJ74_01480	COG1320	monovalent cation:proton antiporter activity
KXJ74_01485	COG2212	antiporter activity
KXJ74_01490	COG1863	multisubunit Na H antiporter MnhE subunit
KXJ74_01495	COG0651	ATP synthesis coupled electron transport
KXJ74_01500	COG1006	Multisubunit Na H antiporter MnhC subunit
KXJ74_01505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KXJ74_01505	COG2111	Na H antiporter
KXJ74_01520	COG0140	phosphoribosyl-ATP diphosphatase activity
KXJ74_01520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KXJ74_01525	COG4221	oxidoreductase activity
KXJ74_01530	COG2873	o-acetylhomoserine
KXJ74_01535	COG0488	(ABC) transporter
KXJ74_01565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ74_01575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ74_01580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ74_01605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KXJ74_01610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KXJ74_01615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KXJ74_01620	COG2226	methyltransferase
KXJ74_01670	COG0070	glutamate synthase
KXJ74_01670	COG0069	glutamate synthase activity
KXJ74_01670	COG0067	glutamate synthase
KXJ74_01675	COG0493	'glutamate synthase
KXJ74_01685	COG1704	LemA family
KXJ74_01690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KXJ74_01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KXJ74_01745	COG1758	RNA polymerase activity
KXJ74_01750	COG0194	GDP metabolic process
KXJ74_01770	COG4966	pilus assembly protein PilW
KXJ74_01795	COG0228	four-way junction DNA binding
KXJ74_01800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KXJ74_01820	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KXJ74_01825	COG5380	lipid catabolic process
KXJ74_01830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KXJ74_01840	COG5006	permease, DMT superfamily
KXJ74_01850	COG5006	permease, DMT superfamily
KXJ74_01855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KXJ74_01860	COG0277	FAD linked oxidase domain protein
KXJ74_01885	COG2814	Major facilitator Superfamily
KXJ74_01900	COG2032	superoxide dismutase activity
KXJ74_01905	COG0628	permease
KXJ74_01925	COG2226	methyltransferase
KXJ74_01945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KXJ74_01950	COG0254	rRNA binding
KXJ74_01975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ74_01985	COG1960	acyl-CoA dehydrogenase activity
KXJ74_02005	COG0408	coproporphyrinogen oxidase activity
KXJ74_02010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KXJ74_02040	COG1127	ABC transporter
KXJ74_02065	COG0598	Magnesium transport protein CorA
KXJ74_02080	COG1040	competence protein
KXJ74_02085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KXJ74_02100	COG2937	Belongs to the GPAT DAPAT family
KXJ74_02105	COG1946	Acyl-CoA thioesterase
KXJ74_02115	COG1301	dicarboxylic acid transport
KXJ74_02135	COG1959	2 iron, 2 sulfur cluster binding
KXJ74_02145	COG0433	COG0433 Predicted ATPase
KXJ74_02160	COG0051	transcription antitermination factor activity, RNA binding
KXJ74_02165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KXJ74_02185	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KXJ74_02235	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KXJ74_02240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KXJ74_02250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KXJ74_02290	COG0202	RNA polymerase activity
KXJ74_02295	COG0203	ribosomal protein L17
KXJ74_02305	COG2945	thiolester hydrolase activity
KXJ74_02305	COG0596	Alpha beta hydrolase
KXJ74_02310	COG1960	acyl-CoA dehydrogenase activity
KXJ74_02315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KXJ74_02350	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KXJ74_02355	COG0339	signal peptide processing
KXJ74_02400	COG0179	Fumarylacetoacetate (FAA) hydrolase
KXJ74_02415	COG1295	ribonuclease BN
KXJ74_02435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KXJ74_02470	COG1702	phosphate starvation-inducible protein PhoH
KXJ74_02475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KXJ74_02480	COG0739	heme binding
KXJ74_02480	COG1196	nuclear chromosome segregation
KXJ74_02480	COG0741	lytic transglycosylase activity
KXJ74_02515	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KXJ74_02520	COG1183	phosphatidylcholine synthase activity
KXJ74_02585	COG1607	acyl-coa hydrolase
KXJ74_02600	COG1666	GTP binding
KXJ74_02620	COG2350	Protein conserved in bacteria
KXJ74_02630	COG0613	PHP domain protein
KXJ74_02635	COG3781	membrane
KXJ74_02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KXJ74_02655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KXJ74_02755	COG0640	Transcriptional regulator
KXJ74_02765	COG0798	PFAM Bile acid sodium symporter
KXJ74_02770	COG0431	NADPH-dependent FMN reductase
KXJ74_02775	COG0492	ferredoxin-NADP+ reductase activity
KXJ74_02790	COG2072	flavoprotein involved in K transport
KXJ74_02810	COG2814	Major facilitator Superfamily
KXJ74_02815	COG0697	spore germination
KXJ74_02835	COG0004	ammonium transporteR
KXJ74_02850	COG3622	Belongs to the hyi family
KXJ74_02855	COG2084	Dehydrogenase
KXJ74_02885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KXJ74_02905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KXJ74_02930	COG2986	histidine ammonia-lyase
KXJ74_02970	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_02975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KXJ74_02985	COG0736	holo-[acyl-carrier-protein] synthase activity
KXJ74_03000	COG1862	Preprotein translocase
KXJ74_03005	COG0343	queuine tRNA-ribosyltransferase activity
KXJ74_03015	COG1704	LemA family
KXJ74_03025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KXJ74_03045	COG5002	protein histidine kinase activity
KXJ74_03050	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KXJ74_03070	COG0726	polysaccharide deacetylase
KXJ74_03080	COG0438	transferase activity, transferring glycosyl groups
KXJ74_03100	COG1088	dTDP-glucose 4,6-dehydratase activity
KXJ74_03105	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KXJ74_03125	COG1216	Glycosyl transferase, family 2
KXJ74_03125	COG0463	Glycosyl transferase, family 2
KXJ74_03140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KXJ74_03170	COG3223	Belongs to the PsiE family
KXJ74_03185	COG1960	acyl-CoA dehydrogenase activity
KXJ74_03190	COG1960	acyl-CoA dehydrogenase activity
KXJ74_03200	COG2205	protein histidine kinase activity
KXJ74_03205	COG0745	RESPONSE REGULATOR receiver
KXJ74_03215	COG1113	amino acid transport
KXJ74_03235	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KXJ74_03260	COG2096	Adenosyltransferase
KXJ74_03265	COG4206	TonB-dependent receptor
KXJ74_03270	COG4206	TonB-dependent receptor
KXJ74_03315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KXJ74_03320	COG0285	dihydrofolate synthase activity
KXJ74_03340	COG0450	alkyl hydroperoxide reductase
KXJ74_03355	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KXJ74_03360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KXJ74_03455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KXJ74_03460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KXJ74_03510	COG0494	nUDIX hydrolase
KXJ74_03515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KXJ74_03520	COG1214	PFAM Peptidase M22, glycoprotease
KXJ74_03525	COG1968	undecaprenyl-diphosphatase activity
KXJ74_03540	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KXJ74_03545	COG4269	membrane
KXJ74_03560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KXJ74_03570	COG2132	Multicopper oxidase
KXJ74_03595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KXJ74_03610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KXJ74_03625	COG3121	Chaperone
KXJ74_03630	COG3188	usher protein
KXJ74_03655	COG3545	Serine hydrolase
KXJ74_03670	COG0730	response to heat
KXJ74_03700	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
KXJ74_03705	COG2193	ferroxidase activity
KXJ74_03710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KXJ74_03725	COG2226	methyltransferase
KXJ74_03725	COG2267	carboxylic ester hydrolase activity
KXJ74_03755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KXJ74_03760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KXJ74_03775	COG0009	L-threonylcarbamoyladenylate synthase
KXJ74_03780	COG3101	peptidyl-lysine hydroxylation
KXJ74_03785	COG1399	metal-binding, possibly nucleic acid-binding protein
KXJ74_03790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KXJ74_03800	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_03815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KXJ74_03825	COG0251	oxidation-reduction process
KXJ74_03830	COG1113	amino acid transport
KXJ74_03840	COG1981	membrane
KXJ74_03885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KXJ74_03890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KXJ74_03895	COG0492	ferredoxin-NADP+ reductase activity
KXJ74_03900	COG0531	amino acid
KXJ74_03900	COG1674	ftsk spoiiie
KXJ74_03910	COG0583	DNA-binding transcription factor activity
KXJ74_03945	COG0204	Acyl-transferase
KXJ74_03955	COG0210	DNA helicase
KXJ74_03960	COG0756	dUTP diphosphatase activity
KXJ74_03970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KXJ74_03980	COG0121	glutamine amidotransferase
KXJ74_03995	COG2914	Belongs to the UPF0125 (RnfH) family
KXJ74_04000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ74_04005	COG0735	belongs to the Fur family
KXJ74_04040	COG0420	3'-5' exonuclease activity
KXJ74_04050	COG2203	Gaf domain
KXJ74_04050	COG3706	GGDEF domain
KXJ74_04050	COG4251	negative regulation of phosphorylation
KXJ74_04050	COG5001	Diguanylate cyclase
KXJ74_04080	COG2050	protein possibly involved in aromatic compounds catabolism
KXJ74_04085	COG1566	PFAM secretion protein HlyD family protein
KXJ74_04090	COG2814	Major facilitator Superfamily
KXJ74_04095	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KXJ74_04105	COG0582	viral genome integration into host DNA
KXJ74_04175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KXJ74_04190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KXJ74_04205	COG1160	GTP binding
KXJ74_04230	COG1448	Aminotransferase
KXJ74_04255	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KXJ74_04290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KXJ74_04300	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KXJ74_04305	COG1077	Cell shape determining protein MreB Mrl
KXJ74_04310	COG1792	Involved in formation and maintenance of cell shape
KXJ74_04315	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KXJ74_04320	COG0424	maF-like protein
KXJ74_04325	COG1530	ribonuclease E activity
KXJ74_04335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KXJ74_04370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KXJ74_04375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KXJ74_04380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KXJ74_04385	COG2205	protein histidine kinase activity
KXJ74_04390	COG0745	RESPONSE REGULATOR receiver
KXJ74_04410	COG1113	amino acid transport
KXJ74_04415	COG2828	Protein conserved in bacteria
KXJ74_04420	COG0142	geranyltranstransferase activity
KXJ74_04425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KXJ74_04440	COG1752	Esterase of the alpha-beta hydrolase superfamily
KXJ74_04465	COG0745	RESPONSE REGULATOR receiver
KXJ74_04470	COG0642	Histidine kinase
KXJ74_04485	COG0004	ammonium transporteR
KXJ74_04490	COG1126	abc transporter atp-binding protein
KXJ74_04500	COG0765	amino acid transport
KXJ74_04535	COG0525	valine-tRNA ligase activity
KXJ74_04545	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_04555	COG0393	Putative heavy-metal-binding
KXJ74_04560	COG0393	Putative heavy-metal-binding
KXJ74_04565	COG1538	Outer membrane efflux protein
KXJ74_04570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ74_04575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_04580	COG0671	phosphoesterase, PA-phosphatase related
KXJ74_04610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KXJ74_04620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KXJ74_04625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KXJ74_04625	COG1648	precorrin-2 dehydrogenase activity
KXJ74_04630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KXJ74_04640	COG0531	amino acid
KXJ74_04655	COG0321	lipoyl(octanoyl) transferase activity
KXJ74_04685	COG0586	Pfam SNARE associated Golgi protein
KXJ74_04720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ74_04750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KXJ74_04780	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KXJ74_04795	COG0358	DNA primase activity
KXJ74_04805	COG0564	pseudouridine synthase activity
KXJ74_04820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KXJ74_04830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ74_04855	COG0110	maltose O-acetyltransferase activity
KXJ74_04860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KXJ74_04870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KXJ74_04875	COG0505	Belongs to the CarA family
KXJ74_04895	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KXJ74_04900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KXJ74_04905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KXJ74_04935	COG1253	flavin adenine dinucleotide binding
KXJ74_04960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ74_04980	COG0741	lytic transglycosylase activity
KXJ74_04980	COG1196	nuclear chromosome segregation
KXJ74_04980	COG0739	heme binding
KXJ74_04985	COG0037	tRNA processing
KXJ74_04995	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KXJ74_05000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ74_05020	COG2814	Major facilitator Superfamily
KXJ74_05035	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ74_05045	COG0154	amidase activity
KXJ74_05070	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_05080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_05085	COG0154	amidase activity
KXJ74_05105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KXJ74_05110	COG0183	Belongs to the thiolase family
KXJ74_05115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KXJ74_05120	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KXJ74_05125	COG4829	muconolactone delta-isomerase
KXJ74_05130	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ74_05135	COG0583	DNA-binding transcription factor activity
KXJ74_05140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KXJ74_05145	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KXJ74_05150	COG3485	protocatechuate 3,4-dioxygenase
KXJ74_05170	COG0411	ABC transporter
KXJ74_05180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KXJ74_05195	COG0456	acetyltransferase
KXJ74_05200	COG1396	sequence-specific DNA binding
KXJ74_05230	COG4774	siderophore transport
KXJ74_05235	COG3712	iron ion homeostasis
KXJ74_05255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_05265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ74_05310	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KXJ74_05330	COG5001	Diguanylate cyclase
KXJ74_05330	COG3300	MHYT domain
KXJ74_05335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KXJ74_05340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KXJ74_05345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KXJ74_05365	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KXJ74_05380	COG1113	amino acid transport
KXJ74_05390	COG0019	diaminopimelate decarboxylase activity
KXJ74_05400	COG0596	Alpha beta hydrolase
KXJ74_05410	COG0154	amidase activity
KXJ74_05425	COG1522	sequence-specific DNA binding
KXJ74_05430	COG1280	lysine exporter protein (LysE YggA)
KXJ74_05475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_05505	COG1671	Belongs to the UPF0178 family
KXJ74_05510	COG0697	spore germination
KXJ74_05525	COG1136	(ABC) transporter
KXJ74_05550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KXJ74_05555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KXJ74_05560	COG0628	permease
KXJ74_05595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KXJ74_05615	COG0823	Involved in the tonB-independent uptake of proteins
KXJ74_05640	COG0824	Thioesterase
KXJ74_05645	COG1473	amidohydrolase
KXJ74_05660	COG2255	four-way junction helicase activity
KXJ74_05685	COG0047	phosphoribosylformylglycinamidine synthase activity
KXJ74_05685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KXJ74_05695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KXJ74_05695	COG3323	Protein of unknown function (DUF1653)
KXJ74_05700	COG0778	Nitroreductase
KXJ74_05705	COG1024	Enoyl-CoA hydratase
KXJ74_05710	COG1051	belongs to the nudix hydrolase family
KXJ74_05710	COG1056	cytidyltransferase-related domain
KXJ74_05715	COG2353	YceI-like domain
KXJ74_05720	COG0583	DNA-binding transcription factor activity
KXJ74_05730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KXJ74_05745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KXJ74_05750	COG0602	queuosine metabolic process
KXJ74_05770	COG0583	DNA-binding transcription factor activity
KXJ74_05775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KXJ74_05780	COG4208	sulfate ABC transporter
KXJ74_05795	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ74_05800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KXJ74_05810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KXJ74_05840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ74_05855	COG0681	Belongs to the peptidase S26 family
KXJ74_05865	COG0571	ribonuclease III activity
KXJ74_05870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KXJ74_05880	COG1381	Involved in DNA repair and RecF pathway recombination
KXJ74_05885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KXJ74_05925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KXJ74_05930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KXJ74_05935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KXJ74_05945	COG0596	Alpha beta hydrolase
KXJ74_05950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ74_05955	COG1335	isochorismatase
KXJ74_05960	COG0251	oxidation-reduction process
KXJ74_05965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_05970	COG2233	PERMEase
KXJ74_05990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KXJ74_06000	COG2175	clavaminate synthase activity
KXJ74_06025	COG3706	GGDEF domain
KXJ74_06035	COG0556	nucleotide-excision repair
KXJ74_06065	COG0702	epimerase
KXJ74_06070	COG1733	regulation of RNA biosynthetic process
KXJ74_06095	COG0671	phosphoesterase, PA-phosphatase related
KXJ74_06100	COG4772	TonB-dependent receptor
KXJ74_06110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KXJ74_06115	COG0076	glutamate decarboxylase activity
KXJ74_06120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KXJ74_06125	COG0573	inorganic phosphate transmembrane transporter activity
KXJ74_06135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KXJ74_06140	COG0616	signal peptide processing
KXJ74_06175	COG2915	High frequency lysogenization protein hflD homolog
KXJ74_06195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KXJ74_06200	COG1686	Belongs to the peptidase S11 family
KXJ74_06225	COG0583	DNA-binding transcription factor activity
KXJ74_06230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KXJ74_06235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KXJ74_06240	COG1067	ATP-dependent peptidase activity
KXJ74_06285	COG1966	Carbon starvation protein
KXJ74_06290	COG2879	small protein
KXJ74_06300	COG0714	Associated with various cellular activities
KXJ74_06320	COG1518	maintenance of DNA repeat elements
KXJ74_06345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KXJ74_06350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_06355	COG0730	response to heat
KXJ74_06360	COG2707	UPF0756 membrane protein
KXJ74_06385	COG0802	atpase or kinase
KXJ74_06390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KXJ74_06400	COG1923	regulation of RNA biosynthetic process
KXJ74_06405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KXJ74_06420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KXJ74_06430	COG1192	Involved in chromosome partitioning
KXJ74_06435	COG1475	DNA binding
KXJ74_06440	COG0811	peptide transport
KXJ74_06450	COG1132	(ABC) transporter
KXJ74_06455	COG1663	tetraacyldisaccharide 4'-kinase activity
KXJ74_06475	COG0084	hydrolase, TatD family'
KXJ74_06510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KXJ74_06515	COG1024	Enoyl-CoA hydratase
KXJ74_06540	COG0776	regulation of translation
KXJ74_06555	COG2431	L-lysine efflux transmembrane transporter activity
KXJ74_06570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KXJ74_06575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KXJ74_06595	COG1253	flavin adenine dinucleotide binding
KXJ74_06620	COG0308	aminopeptidase N
KXJ74_06630	COG1714	RDD family
KXJ74_06640	COG0589	response to stress
KXJ74_06655	COG1309	transcriptional regulator
KXJ74_06660	COG3135	benzoate transporter
KXJ74_06675	COG0583	DNA-binding transcription factor activity
KXJ74_06685	COG1403	HNH endonuclease
KXJ74_06700	COG2030	dehydratase
KXJ74_06705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KXJ74_06725	COG0824	Thioesterase
KXJ74_06730	COG1454	alcohol dehydrogenase
KXJ74_06735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KXJ74_06755	COG0069	glutamate synthase activity
KXJ74_06765	COG2308	Evidence 4 Homologs of previously reported genes of
KXJ74_06775	COG1305	Transglutaminase-like
KXJ74_06785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KXJ74_06800	COG0305	Participates in initiation and elongation during chromosome replication
KXJ74_06815	COG0360	Binds together with S18 to 16S ribosomal RNA
KXJ74_06835	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KXJ74_06840	COG1845	cytochrome c oxidase, subunit III
KXJ74_06845	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KXJ74_06850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KXJ74_06875	COG4682	membrane
KXJ74_06880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ74_06900	COG2890	protein-(glutamine-N5) methyltransferase activity
KXJ74_06905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ74_06910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ74_06930	COG1960	acyl-CoA dehydrogenase activity
KXJ74_06935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ74_06950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KXJ74_06960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KXJ74_06985	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KXJ74_06995	COG0729	surface antigen
KXJ74_07070	COG0786	glutamate:sodium symporter activity
KXJ74_07140	COG4197	protein conserved in bacteria, prophage-related
KXJ74_07405	COG1114	Component of the transport system for branched-chain amino acids
KXJ74_07410	COG0024	Methionine aminopeptidase
KXJ74_07415	COG0583	DNA-binding transcription factor activity
KXJ74_07420	COG0583	DNA-binding transcription factor activity
KXJ74_07425	COG0596	Alpha beta hydrolase
KXJ74_07435	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ74_07435	COG1902	pentaerythritol trinitrate reductase activity
KXJ74_07450	COG2814	Major facilitator Superfamily
KXJ74_07455	COG0656	L-ascorbic acid biosynthetic process
KXJ74_07480	COG0148	phosphopyruvate hydratase activity
KXJ74_07495	COG0772	Belongs to the SEDS family
KXJ74_07510	COG4890	Cyd operon protein YbgT
KXJ74_07515	COG1294	oxidase, subunit
KXJ74_07535	COG0537	adenosine 5'-monophosphoramidase activity
KXJ74_07565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KXJ74_07585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KXJ74_07600	COG0133	tryptophan synthase activity
KXJ74_07605	COG0516	GMP reductase activity
KXJ74_07605	COG0517	IMP dehydrogenase activity
KXJ74_07630	COG0612	Peptidase, M16
KXJ74_07635	COG0552	protein localization to endoplasmic reticulum
KXJ74_07695	COG1960	acyl-CoA dehydrogenase activity
KXJ74_07700	COG1960	acyl-CoA dehydrogenase activity
KXJ74_07770	COG0730	response to heat
KXJ74_07785	COG2207	Transcriptional regulator
KXJ74_07790	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KXJ74_07800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KXJ74_07805	COG4716	Myosin-crossreactive antigen
KXJ74_07815	COG2985	domain, Protein
KXJ74_07825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KXJ74_07830	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_07835	COG1169	isochorismate synthase
KXJ74_07840	COG1021	2,3-dihydroxybenzoate-AMP ligase
KXJ74_07845	COG1535	isochorismatase
KXJ74_07845	COG3433	isochorismatase activity
KXJ74_07895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KXJ74_07910	COG1346	cytolysis
KXJ74_07915	COG1380	Effector of murein hydrolase LrgA
KXJ74_07920	COG0583	DNA-binding transcription factor activity
KXJ74_07945	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KXJ74_07950	COG2819	hydrolase of the alpha beta superfamily
KXJ74_08000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KXJ74_08005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KXJ74_08110	COG3549	Plasmid maintenance system killer
KXJ74_08115	COG3093	addiction module antidote protein HigA
KXJ74_08160	COG2814	Major facilitator Superfamily
KXJ74_08170	COG1525	nuclease
KXJ74_08215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ74_08215	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
KXJ74_08235	COG0697	spore germination
KXJ74_08255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ74_08260	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KXJ74_08275	COG0488	(ABC) transporter
KXJ74_08280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KXJ74_08290	COG2814	Major facilitator Superfamily
KXJ74_08295	COG3384	dioxygenase
KXJ74_08300	COG0509	glycine decarboxylation via glycine cleavage system
KXJ74_08325	COG3122	Protein conserved in bacteria
KXJ74_08345	COG0640	Transcriptional regulator
KXJ74_08350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KXJ74_08360	COG0789	Transcriptional regulator
KXJ74_08375	COG1960	acyl-CoA dehydrogenase activity
KXJ74_08380	COG0183	Belongs to the thiolase family
KXJ74_08385	COG0427	acetyl-CoA hydrolase
KXJ74_08400	COG0583	DNA-binding transcription factor activity
KXJ74_08415	COG0439	Biotin carboxylase
KXJ74_08435	COG0864	Transcriptional regulator
KXJ74_08455	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KXJ74_08460	COG1959	2 iron, 2 sulfur cluster binding
KXJ74_08485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KXJ74_08495	COG1960	acyl-CoA dehydrogenase activity
KXJ74_08515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KXJ74_08520	COG0183	Belongs to the thiolase family
KXJ74_08525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KXJ74_08530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KXJ74_08535	COG3135	benzoate transporter
KXJ74_08540	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_08545	COG0633	Ferredoxin
KXJ74_08545	COG0543	2 iron, 2 sulfur cluster binding
KXJ74_08550	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KXJ74_08555	COG4638	Rieske (2fe-2S)
KXJ74_08565	COG4829	muconolactone delta-isomerase
KXJ74_08570	COG4948	Mandelate Racemase Muconate Lactonizing
KXJ74_08575	COG0583	DNA-binding transcription factor activity
KXJ74_08580	COG2814	Major facilitator Superfamily
KXJ74_08615	COG2937	Belongs to the GPAT DAPAT family
KXJ74_08620	COG1944	ATP diphosphatase activity
KXJ74_08635	COG1131	(ABC) transporter
KXJ74_08640	COG0842	Transport permease protein
KXJ74_08645	COG0842	Transport permease protein
KXJ74_08685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KXJ74_08690	COG4149	molybdate abc transporter
KXJ74_08695	COG0725	ABC transporter, periplasmic molybdate-binding protein
KXJ74_08700	COG0303	'Molybdopterin
KXJ74_08705	COG0315	cyclic pyranopterin monophosphate synthase activity
KXJ74_08705	COG0521	Mo-molybdopterin cofactor biosynthetic process
KXJ74_08710	COG0314	molybdopterin synthase activity
KXJ74_08720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KXJ74_08730	COG0243	molybdopterin cofactor binding
KXJ74_08735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ74_08740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ74_08745	COG2223	nitrite transmembrane transporter activity
KXJ74_08755	COG1116	anion transmembrane transporter activity
KXJ74_08755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ74_08865	COG0596	Alpha beta hydrolase
KXJ74_08930	COG0439	Biotin carboxylase
KXJ74_08940	COG2199	diguanylate cyclase activity
KXJ74_08945	COG2814	Major facilitator Superfamily
KXJ74_08955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ74_08960	COG0730	response to heat
KXJ74_08990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KXJ74_08995	COG3038	cytochrome b561
KXJ74_09010	COG2814	Major facilitator Superfamily
KXJ74_09155	COG3121	Chaperone
KXJ74_09190	COG0583	DNA-binding transcription factor activity
KXJ74_09200	COG4106	trans-aconitate 2-methyltransferase activity
KXJ74_09205	COG2807	transmembrane transport
KXJ74_09225	COG1846	Transcriptional regulator
KXJ74_09245	COG0789	Transcriptional regulator
KXJ74_09285	COG0281	malic enzyme
KXJ74_09295	COG0415	Belongs to the DNA photolyase family
KXJ74_09335	COG0372	Belongs to the citrate synthase family
KXJ74_09365	COG0542	response to heat
KXJ74_09370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KXJ74_09400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KXJ74_09405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KXJ74_09420	COG0569	domain protein
KXJ74_09425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KXJ74_09450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KXJ74_09515	COG0822	iron-sulfur transferase activity
KXJ74_09520	COG0316	Belongs to the HesB IscA family
KXJ74_09550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KXJ74_09560	COG1027	Aspartate ammonia-lyase
KXJ74_09565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KXJ74_09605	COG3781	membrane
KXJ74_09610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KXJ74_09620	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ74_09670	COG0424	maF-like protein
KXJ74_09675	COG2850	peptidyl-arginine hydroxylation
KXJ74_09680	COG4585	Histidine kinase
KXJ74_09695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KXJ74_09700	COG0702	epimerase
KXJ74_09725	COG1218	3'(2'),5'-bisphosphate nucleotidase
KXJ74_09730	COG1011	Hydrolase
KXJ74_09735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KXJ74_09745	COG2137	regulation of response to DNA damage stimulus
KXJ74_09765	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ74_09775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KXJ74_09785	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ74_09800	COG0575	Belongs to the CDS family
KXJ74_09805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KXJ74_09825	COG3852	Histidine kinase
KXJ74_09840	COG2814	Major facilitator Superfamily
KXJ74_09880	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KXJ74_09885	COG0138	bifunctional purine biosynthesis protein purh
KXJ74_09890	COG0151	Belongs to the GarS family
KXJ74_09900	COG1464	Belongs to the NlpA lipoprotein family
KXJ74_09905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KXJ74_09910	COG2011	ABC-type metal ion transport system permease component
KXJ74_09950	COG3706	GGDEF domain
KXJ74_09955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KXJ74_09960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KXJ74_09970	COG4122	O-methyltransferase activity
KXJ74_09975	COG0589	response to stress
KXJ74_10005	COG1137	ATPase activity
KXJ74_10010	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KXJ74_10020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KXJ74_10025	COG0517	IMP dehydrogenase activity
KXJ74_10025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KXJ74_10050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KXJ74_10050	COG0519	Catalyzes the synthesis of GMP from XMP
KXJ74_10055	COG1280	lysine exporter protein (LysE YggA)
KXJ74_10085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KXJ74_10090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KXJ74_10110	COG2070	2-Nitropropane dioxygenase
KXJ74_10130	COG1215	transferase activity, transferring glycosyl groups
KXJ74_10135	COG1649	PFAM Uncharacterised BCR, COG1649
KXJ74_10135	COG0726	polysaccharide deacetylase
KXJ74_10165	COG2197	response regulator
KXJ74_10220	COG0783	Belongs to the Dps family
KXJ74_10235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KXJ74_10240	COG1335	isochorismatase
KXJ74_10245	COG3193	protein, possibly involved in utilization of glycolate and propanediol
KXJ74_10255	COG0352	thiamine-phosphate diphosphorylase activity
KXJ74_10290	COG0612	Peptidase, M16
KXJ74_10300	COG1823	symporter activity
KXJ74_10305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_10360	COG0515	serine threonine protein kinase
KXJ74_10360	COG2815	serine threonine protein kinase
KXJ74_10390	COG1610	YqeY-like protein
KXJ74_10435	COG0167	dihydroorotate dehydrogenase activity
KXJ74_10460	COG0778	Nitroreductase
KXJ74_10470	COG0513	Belongs to the DEAD box helicase family
KXJ74_10475	COG1278	Cold shock
KXJ74_10490	COG2363	Small membrane protein
KXJ74_10515	COG2249	NAD(P)H dehydrogenase (quinone) activity
KXJ74_10520	COG0625	glutathione transferase activity
KXJ74_10525	COG0659	secondary active sulfate transmembrane transporter activity
KXJ74_10535	COG4585	Histidine kinase
KXJ74_10570	COG3047	cAMP biosynthetic process
KXJ74_10570	COG2885	chlorophyll binding
KXJ74_10580	COG0540	Belongs to the ATCase OTCase family
KXJ74_10625	COG0542	response to heat
KXJ74_10630	COG0667	Aldo Keto reductase
KXJ74_10640	COG1765	OsmC-like protein
KXJ74_10650	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KXJ74_10655	COG2072	flavoprotein involved in K transport
KXJ74_10685	COG5285	phytanoyl-CoA dioxygenase
KXJ74_10700	COG1126	abc transporter atp-binding protein
KXJ74_10730	COG0583	DNA-binding transcription factor activity
KXJ74_10735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ74_10740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KXJ74_10820	COG1254	Belongs to the acylphosphatase family
KXJ74_10825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KXJ74_10825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KXJ74_10865	COG2814	Major facilitator Superfamily
KXJ74_10870	COG1846	Transcriptional regulator
KXJ74_10880	COG2271	Major facilitator Superfamily
KXJ74_10890	COG1414	Transcriptional regulator
KXJ74_10895	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_10905	COG1053	succinate dehydrogenase
KXJ74_10910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_10915	COG1960	acyl-CoA dehydrogenase activity
KXJ74_10955	COG3971	2-oxopent-4-enoate hydratase activity
KXJ74_10965	COG3384	dioxygenase
KXJ74_10970	COG1012	belongs to the aldehyde dehydrogenase family
KXJ74_10980	COG0179	Fumarylacetoacetate (FAA) hydrolase
KXJ74_10990	COG2814	Major facilitator Superfamily
KXJ74_11005	COG4774	siderophore transport
KXJ74_11030	COG2274	protein secretion by the type I secretion system
KXJ74_11035	COG1538	Outer membrane efflux protein
KXJ74_11065	COG0204	Acyl-transferase
KXJ74_11105	COG1464	Belongs to the NlpA lipoprotein family
KXJ74_11110	COG1464	Belongs to the NlpA lipoprotein family
KXJ74_11115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KXJ74_11120	COG2011	ABC-type metal ion transport system permease component
KXJ74_11125	COG0012	GTP binding
KXJ74_11140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KXJ74_11155	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KXJ74_11170	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KXJ74_11185	COG0386	Belongs to the glutathione peroxidase family
KXJ74_11190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KXJ74_11195	COG0436	Aminotransferase
KXJ74_11240	COG1686	Belongs to the peptidase S11 family
KXJ74_11245	COG1252	NADH dehydrogenase
KXJ74_11265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KXJ74_11285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KXJ74_11300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KXJ74_11310	COG0527	aspartate kinase activity
KXJ74_11320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KXJ74_11330	COG3038	cytochrome b561
KXJ74_11340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KXJ74_11345	COG2252	PERMEase
KXJ74_11375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KXJ74_11380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KXJ74_11390	COG0693	protein deglycase activity
KXJ74_11395	COG1960	acyl-CoA dehydrogenase activity
KXJ74_11400	COG1301	dicarboxylic acid transport
KXJ74_11415	COG3139	Protein of unknown function (DUF1315)
KXJ74_11420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KXJ74_11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KXJ74_11435	COG0494	nUDIX hydrolase
KXJ74_11460	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KXJ74_11480	COG4993	Dehydrogenase
KXJ74_11510	COG0789	Transcriptional regulator
KXJ74_11515	COG0431	NADPH-dependent FMN reductase
KXJ74_11520	COG0798	PFAM Bile acid sodium symporter
KXJ74_11525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KXJ74_11535	COG0826	peptidase U32
KXJ74_11540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KXJ74_11555	COG3634	alkyl hydroperoxide reductase activity
KXJ74_11580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KXJ74_11615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KXJ74_11620	COG0010	Belongs to the arginase family
KXJ74_11630	COG1113	amino acid transport
KXJ74_11655	COG0372	Belongs to the citrate synthase family
KXJ74_11665	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ74_11690	COG2855	membrane
KXJ74_11695	COG2146	nitrite reductase [NAD(P)H] activity
KXJ74_11705	COG2814	Major facilitator Superfamily
KXJ74_11710	COG3246	L-lysine catabolic process to acetate
KXJ74_11715	COG2175	clavaminate synthase activity
KXJ74_11730	COG1968	undecaprenyl-diphosphatase activity
KXJ74_11775	COG4993	Dehydrogenase
KXJ74_11780	COG3659	wide pore channel activity
KXJ74_11785	COG3420	alginic acid biosynthetic process
KXJ74_11790	COG0710	3-dehydroquinate dehydratase activity
KXJ74_11795	COG3485	protocatechuate 3,4-dioxygenase
KXJ74_11800	COG3485	protocatechuate 3,4-dioxygenase
KXJ74_11805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KXJ74_11810	COG2271	Major facilitator Superfamily
KXJ74_11815	COG0596	Alpha beta hydrolase
KXJ74_11825	COG0183	Belongs to the thiolase family
KXJ74_11830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KXJ74_11835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KXJ74_11840	COG1414	Transcriptional regulator
KXJ74_11850	COG4774	siderophore transport
KXJ74_11870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ74_11880	COG1271	oxidase subunit
KXJ74_11885	COG1294	oxidase, subunit
KXJ74_11890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KXJ74_11925	COG2871	sodium ion transport
KXJ74_11955	COG1960	acyl-CoA dehydrogenase activity
KXJ74_11960	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ74_11965	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ74_11965	COG1024	Enoyl-CoA hydratase
KXJ74_11970	COG1024	Enoyl-CoA hydratase
KXJ74_11975	COG2814	Major facilitator Superfamily
KXJ74_11980	COG1846	Transcriptional regulator
KXJ74_12035	COG1271	oxidase subunit
KXJ74_12040	COG1294	oxidase, subunit
KXJ74_12055	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_12070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KXJ74_12100	COG0523	cobalamin synthesis protein
KXJ74_12120	COG0735	belongs to the Fur family
KXJ74_12125	COG1469	GTP cyclohydrolase I activity
KXJ74_12130	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KXJ74_12135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KXJ74_12135	COG4451	ribulose bisphosphate carboxylase, small
KXJ74_12140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KXJ74_12145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KXJ74_12165	COG3038	cytochrome b561
KXJ74_12170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KXJ74_12200	COG0745	RESPONSE REGULATOR receiver
KXJ74_12205	COG0642	Histidine kinase
KXJ74_12210	COG4106	trans-aconitate 2-methyltransferase activity
KXJ74_12220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KXJ74_12260	COG2816	NAD+ diphosphatase activity
KXJ74_12265	COG3046	protein related to deoxyribodipyrimidine photolyase
KXJ74_12280	COG2351	hydroxyisourate hydrolase activity
KXJ74_12300	COG2203	Gaf domain
KXJ74_12300	COG2199	diguanylate cyclase activity
KXJ74_12345	COG3311	Transcriptional regulator
KXJ74_12355	COG3152	Membrane
KXJ74_12370	COG0582	viral genome integration into host DNA
KXJ74_12380	COG1131	(ABC) transporter
KXJ74_12385	COG0842	Transport permease protein
KXJ74_12400	COG2951	lytic endotransglycosylase activity
KXJ74_12440	COG0052	Belongs to the universal ribosomal protein uS2 family
KXJ74_12450	COG0436	Aminotransferase
KXJ74_12520	COG0625	glutathione transferase activity
KXJ74_12530	COG0583	DNA-binding transcription factor activity
KXJ74_12540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KXJ74_12550	COG3733	amine oxidase
KXJ74_12585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KXJ74_12590	COG3161	chorismate lyase activity
KXJ74_12600	COG0174	glutamine synthetase
KXJ74_12605	COG0512	Glutamine amidotransferase of anthranilate synthase
KXJ74_12610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KXJ74_12635	COG0302	gtp cyclohydrolase
KXJ74_12650	COG3706	GGDEF domain
KXJ74_12685	COG1741	Belongs to the pirin family
KXJ74_12700	COG1902	pentaerythritol trinitrate reductase activity
KXJ74_12700	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ74_12705	COG0277	FAD linked oxidase domain protein
KXJ74_12715	COG2186	Transcriptional regulator
KXJ74_12730	COG0697	spore germination
KXJ74_12735	COG0583	DNA-binding transcription factor activity
KXJ74_12745	COG3706	GGDEF domain
KXJ74_12750	COG0418	dihydroorotase activity
KXJ74_12755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KXJ74_12760	COG4771	TonB-dependent receptor
KXJ74_12765	COG0833	amino acid
KXJ74_12780	COG0833	amino acid
KXJ74_12805	COG0625	glutathione transferase activity
KXJ74_12815	COG4172	Belongs to the ABC transporter superfamily
KXJ74_12835	COG0741	lytic transglycosylase activity
KXJ74_12835	COG1388	LysM domain
KXJ74_12850	COG2816	NAD+ diphosphatase activity
KXJ74_12855	COG0657	acetylesterase activity
KXJ74_12895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KXJ74_12900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KXJ74_12900	COG0456	acetyltransferase
KXJ74_12910	COG0006	proline dipeptidase activity
KXJ74_12950	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KXJ74_12965	COG2234	aminopeptidase activity
KXJ74_12975	COG3384	dioxygenase
KXJ74_12985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KXJ74_12990	COG2878	Part of a membrane complex involved in electron transport
KXJ74_12995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KXJ74_13020	COG0768	penicillin binding
KXJ74_13025	COG0742	ribosomal rna small subunit methyltransferase
KXJ74_13055	COG3015	lipoprotein NlpE involved in copper resistance
KXJ74_13095	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
KXJ74_13110	COG0477	Major facilitator Superfamily
KXJ74_13115	COG0477	Major facilitator Superfamily
KXJ74_13130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KXJ74_13180	COG1695	Transcriptional regulator
KXJ74_13205	COG1585	Membrane protein implicated in regulation of membrane protease activity
KXJ74_13210	COG2268	Band 7 protein
KXJ74_13215	COG1649	PFAM Uncharacterised BCR, COG1649
KXJ74_13215	COG0726	polysaccharide deacetylase
KXJ74_13225	COG1215	transferase activity, transferring glycosyl groups
KXJ74_13230	COG1649	PFAM Uncharacterised BCR, COG1649
KXJ74_13230	COG0726	polysaccharide deacetylase
KXJ74_13240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KXJ74_13250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ74_13265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KXJ74_13270	COG1053	succinate dehydrogenase
KXJ74_13275	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KXJ74_13280	COG2009	succinate dehydrogenase
KXJ74_13290	COG2072	flavoprotein involved in K transport
KXJ74_13295	COG0300	oxidoreductase activity
KXJ74_13305	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KXJ74_13310	COG0714	Associated with various cellular activities
KXJ74_13360	COG2321	neutral zinc metallopeptidase
KXJ74_13365	COG2354	Protein conserved in bacteria
KXJ74_13390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KXJ74_13395	COG1773	rubredoxin
KXJ74_13400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ74_13410	COG0583	DNA-binding transcription factor activity
KXJ74_13465	COG4771	TonB-dependent receptor
KXJ74_13495	COG0306	phosphate transporter
KXJ74_13510	COG2852	Protein conserved in bacteria
KXJ74_13520	COG2223	nitrite transmembrane transporter activity
KXJ74_13525	COG2207	Transcriptional regulator
KXJ74_13530	COG0242	peptide deformylase activity
KXJ74_13545	COG0477	Major facilitator Superfamily
KXJ74_13560	COG1024	Enoyl-CoA hydratase
KXJ74_13590	COG2199	diguanylate cyclase activity
KXJ74_13590	COG2203	Gaf domain
KXJ74_13605	COG4681	YaeQ
KXJ74_13610	COG0523	cobalamin synthesis protein
KXJ74_13630	COG0583	DNA-binding transcription factor activity
KXJ74_13635	COG2814	Major facilitator Superfamily
KXJ74_13650	COG1607	acyl-coa hydrolase
KXJ74_13660	COG1752	Esterase of the alpha-beta hydrolase superfamily
KXJ74_13665	COG0786	glutamate:sodium symporter activity
KXJ74_13680	COG2814	Major facilitator Superfamily
KXJ74_13685	COG1289	transmembrane transporter activity
KXJ74_13695	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KXJ74_13755	COG2832	Protein of unknown function (DUF454)
KXJ74_13780	COG0643	Histidine kinase
KXJ74_13780	COG2198	Histidine kinase
KXJ74_13785	COG0840	transmembrane signaling receptor activity
KXJ74_13810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_13820	COG0442	prolyl-tRNA aminoacylation
KXJ74_13855	COG0489	protein tyrosine kinase activity
KXJ74_13880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ74_13880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ74_13895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ74_13930	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KXJ74_13935	COG2081	HI0933 family
KXJ74_13950	COG0668	transmembrane transport
KXJ74_13960	COG4302	ethanolamine ammonia-lyase activity
KXJ74_13970	COG0531	amino acid
KXJ74_13985	COG0583	DNA-binding transcription factor activity
KXJ74_13990	COG1278	Cold shock
KXJ74_14010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ74_14015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KXJ74_14020	COG0713	ATP synthesis coupled electron transport
KXJ74_14030	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KXJ74_14045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KXJ74_14075	COG2205	protein histidine kinase activity
KXJ74_14080	COG0745	RESPONSE REGULATOR receiver
KXJ74_14095	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KXJ74_14100	COG3152	Membrane
KXJ74_14105	COG2314	TM2 domain
KXJ74_14125	COG0351	phosphomethylpyrimidine kinase
KXJ74_14125	COG0352	thiamine-phosphate diphosphorylase activity
KXJ74_14125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KXJ74_14135	COG0494	nUDIX hydrolase
KXJ74_14150	COG3422	double-strand break repair
KXJ74_14160	COG2824	Alkylphosphonate utilization operon protein PhnA
KXJ74_14165	COG3189	MarR family transcriptional regulator
KXJ74_14190	COG0564	pseudouridine synthase activity
KXJ74_14260	COG0354	folic acid binding
KXJ74_14300	COG4772	TonB-dependent receptor
KXJ74_14315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KXJ74_14335	COG1217	gtp-binding protein TYPA
KXJ74_14340	COG2233	PERMEase
KXJ74_14350	COG0833	amino acid
KXJ74_14365	COG0183	Belongs to the thiolase family
KXJ74_14380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KXJ74_14395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KXJ74_14400	COG2207	Transcriptional regulator
KXJ74_14415	COG1024	Enoyl-CoA hydratase
KXJ74_14415	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ74_14420	COG1522	sequence-specific DNA binding
KXJ74_14440	COG0583	DNA-binding transcription factor activity
KXJ74_14455	COG1272	protein, Hemolysin III
KXJ74_14460	COG0477	Major facilitator Superfamily
KXJ74_14470	COG1408	metallophosphoesterase
KXJ74_14475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KXJ74_14485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KXJ74_14515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KXJ74_14520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KXJ74_14525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KXJ74_14530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KXJ74_14535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KXJ74_14540	COG0625	glutathione transferase activity
KXJ74_14545	COG2969	positive regulation of protein catabolic process
KXJ74_14600	COG2853	Lipoprotein
KXJ74_14615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KXJ74_14625	COG1764	response to oxidative stress
KXJ74_14675	COG0037	tRNA processing
KXJ74_14685	COG0248	Ppx GppA phosphatase
KXJ74_14710	COG0072	phenylalanine-tRNA ligase activity
KXJ74_14715	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KXJ74_14775	COG1238	metal cluster binding
KXJ74_14790	COG0625	glutathione transferase activity
KXJ74_14800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KXJ74_14810	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ74_14820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KXJ74_14825	COG1660	Displays ATPase and GTPase activities
KXJ74_14840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KXJ74_14845	COG0617	tRNA 3'-terminal CCA addition
KXJ74_14850	COG1555	photosystem II stabilization
KXJ74_14855	COG3956	TIGRFAM MazG family protein
KXJ74_14870	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KXJ74_14950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KXJ74_14960	COG0028	Belongs to the TPP enzyme family
KXJ74_14985	COG2703	oxygen carrier activity
KXJ74_14990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KXJ74_15000	COG1538	Outer membrane efflux protein
KXJ74_15015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KXJ74_15020	COG1162	GTPase activity
KXJ74_15045	COG0084	hydrolase, TatD family'
KXJ74_15060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KXJ74_15075	COG0793	Belongs to the peptidase S41A family
KXJ74_15090	COG2267	carboxylic ester hydrolase activity
KXJ74_15100	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KXJ74_15105	COG0857	belongs to the CobB CobQ family
KXJ74_15105	COG0280	phosphate acetyltransferase
KXJ74_15115	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KXJ74_15115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KXJ74_15135	COG0740	serine-type endopeptidase activity
KXJ74_15145	COG4774	siderophore transport
KXJ74_15150	COG4774	siderophore transport
KXJ74_15155	COG3128	pkhd-type hydroxylase
KXJ74_15165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KXJ74_15175	COG2813	Specifically methylates the guanine in position
KXJ74_15175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KXJ74_15260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KXJ74_15265	COG0784	Response regulator, receiver
KXJ74_15265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KXJ74_15350	COG4651	solute:proton antiporter activity
KXJ74_15350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KXJ74_15375	COG0724	RNA recognition motif
KXJ74_15380	COG0210	DNA helicase
KXJ74_15390	COG1929	Belongs to the glycerate kinase type-1 family
KXJ74_15430	COG2900	Belongs to the SlyX family
KXJ74_15435	COG0488	(ABC) transporter
KXJ74_15440	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_15445	COG1560	Kdo2-lipid A biosynthetic process
KXJ74_15515	COG0473	3-isopropylmalate dehydrogenase activity
KXJ74_15530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KXJ74_15550	COG0583	DNA-binding transcription factor activity
KXJ74_15570	COG0494	nUDIX hydrolase
KXJ74_15590	COG1280	lysine exporter protein (LysE YggA)
KXJ74_15605	COG1960	acyl-CoA dehydrogenase activity
KXJ74_15625	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KXJ74_15655	COG0446	pyridine nucleotide-disulphide oxidoreductase
KXJ74_15660	COG3384	dioxygenase
KXJ74_15665	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_15680	COG4638	Rieske (2fe-2S)
KXJ74_15685	COG0583	DNA-binding transcription factor activity
KXJ74_15710	COG4569	acetaldehyde dehydrogenase (acetylating) activity
KXJ74_15715	COG3971	2-oxopent-4-enoate hydratase activity
KXJ74_15725	COG0546	phosphoglycolate phosphatase activity
KXJ74_15740	COG0318	PFAM AMP-dependent synthetase and ligase
KXJ74_15770	COG1983	PspC domain protein
KXJ74_15775	COG0517	IMP dehydrogenase activity
KXJ74_15785	COG0752	glycyl-tRNA synthetase alpha subunit
KXJ74_15790	COG0751	glycine-tRNA ligase activity
KXJ74_15815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KXJ74_15845	COG0493	'glutamate synthase
KXJ74_15855	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KXJ74_15865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KXJ74_15880	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KXJ74_15890	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KXJ74_15890	COG0644	oxidoreductase
KXJ74_15895	COG0425	Belongs to the sulfur carrier protein TusA family
KXJ74_15900	COG4535	Mg2 and Co2 transporter CorC
KXJ74_15905	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KXJ74_15910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KXJ74_15940	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KXJ74_15960	COG0484	heat shock protein binding
KXJ74_15965	COG0789	Transcriptional regulator
KXJ74_15970	COG2841	Protein conserved in bacteria
KXJ74_15980	COG1185	polyribonucleotide nucleotidyltransferase activity
KXJ74_15995	COG1074	ATP-dependent DNA helicase activity
KXJ74_16000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KXJ74_16030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KXJ74_16070	COG0427	acetyl-CoA hydrolase
KXJ74_16080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KXJ74_16115	COG0326	Molecular chaperone. Has ATPase activity
KXJ74_16130	COG2056	Na+-H+ antiporter family
KXJ74_16155	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KXJ74_16160	COG0085	RNA polymerase activity
KXJ74_16165	COG0222	ribosome binding
KXJ74_16170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KXJ74_16175	COG0081	regulation of translation
KXJ74_16190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KXJ74_16230	COG0546	phosphoglycolate phosphatase activity
KXJ74_16235	COG1716	ATPase activity
KXJ74_16280	COG0181	hydroxymethylbilane synthase activity
KXJ74_16305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KXJ74_16330	COG1024	Enoyl-CoA hydratase
KXJ74_16330	COG1250	3-hydroxyacyl-CoA dehydrogenase
KXJ74_16335	COG0183	Belongs to the thiolase family
KXJ74_16400	COG0131	Imidazoleglycerol-phosphate dehydratase
KXJ74_16405	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KXJ74_16435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KXJ74_16440	COG0531	amino acid
KXJ74_16460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KXJ74_16510	COG3158	transport of potassium into the cell
KXJ74_16550	COG1335	isochorismatase
KXJ74_16580	COG0629	single-stranded DNA binding
KXJ74_16585	COG2814	Major facilitator Superfamily
KXJ74_16610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KXJ74_16635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KXJ74_16640	COG3162	membrane
KXJ74_16645	COG2205	protein histidine kinase activity
KXJ74_16645	COG0784	Response regulator, receiver
KXJ74_16675	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_16685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KXJ74_16695	COG0668	transmembrane transport
KXJ74_16700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KXJ74_16705	COG1519	Transferase
KXJ74_16710	COG1902	pentaerythritol trinitrate reductase activity
KXJ74_16735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KXJ74_16760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KXJ74_16760	COG0426	domain, Protein
KXJ74_16765	COG2119	membrane
KXJ74_16795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KXJ74_16805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KXJ74_16810	COG1181	Belongs to the D-alanine--D-alanine ligase family
KXJ74_16815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KXJ74_16825	COG0189	ligase activity
KXJ74_16840	COG0753	catalase activity
KXJ74_16850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KXJ74_16855	COG0708	Exodeoxyribonuclease III
KXJ74_16860	COG1393	Belongs to the ArsC family
KXJ74_16875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KXJ74_16880	COG3706	GGDEF domain
KXJ74_16885	COG0625	glutathione transferase activity
KXJ74_16915	COG1247	-acetyltransferase
KXJ74_16940	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KXJ74_16945	COG2918	glutathione biosynthetic process
KXJ74_16960	COG2733	membrane
KXJ74_17005	COG0753	catalase activity
KXJ74_17040	COG0385	Bile acid
KXJ74_17045	COG1335	isochorismatase
KXJ74_17050	COG2814	Major facilitator Superfamily
KXJ74_17055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KXJ74_17080	COG1683	Conserved Protein
KXJ74_17085	COG2983	Belongs to the UPF0260 family
KXJ74_17090	COG5487	UPF0391 membrane protein
KXJ74_17115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KXJ74_17125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KXJ74_17130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KXJ74_17135	COG0546	phosphoglycolate phosphatase activity
KXJ74_17140	COG1028	Short-chain dehydrogenase reductase Sdr
KXJ74_17165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KXJ74_17165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KXJ74_17170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ74_17175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KXJ74_17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KXJ74_17185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KXJ74_17190	COG1116	anion transmembrane transporter activity
KXJ74_17195	COG1309	transcriptional regulator
KXJ74_17215	COG0196	riboflavin kinase activity
KXJ74_17220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KXJ74_17230	COG1047	Peptidyl-prolyl cis-trans
KXJ74_17235	COG0431	NADPH-dependent FMN reductase
KXJ74_17260	COG2814	Major facilitator Superfamily
KXJ74_17300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KXJ74_17305	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KXJ74_17310	COG2951	lytic endotransglycosylase activity
KXJ74_17315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KXJ74_17330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KXJ74_17345	COG2388	GCN5-related N-acetyl-transferase
KXJ74_17350	COG2814	Major facilitator Superfamily
KXJ74_17355	COG0861	Integral membrane protein TerC family
KXJ74_17385	COG1230	cation diffusion facilitator family transporter
KXJ74_17405	COG0706	membrane insertase activity
KXJ74_17410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KXJ74_17440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KXJ74_17555	COG4716	Myosin-crossreactive antigen
KXJ74_17605	COG3077	Addiction module antitoxin, RelB DinJ family
KXJ74_17665	COG4191	Histidine kinase
KXJ74_17690	COG1794	racemase activity, acting on amino acids and derivatives
KXJ74_17700	COG2610	gluconate transmembrane transporter activity
KXJ74_17705	COG1454	alcohol dehydrogenase
KXJ74_17715	COG1414	Transcriptional regulator
KXJ74_17740	COG2801	Transposase and inactivated derivatives
KXJ74_17755	COG3550	peptidyl-serine autophosphorylation
KXJ74_17850	COG0739	heme binding
KXJ74_17850	COG1196	nuclear chromosome segregation
KXJ74_17850	COG0741	lytic transglycosylase activity
KXJ74_17865	COG1196	nuclear chromosome segregation
KXJ74_17865	COG0741	lytic transglycosylase activity
KXJ74_17865	COG0739	heme binding
KXJ74_17920	COG1192	Involved in chromosome partitioning
KXJ74_17980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KXJ74_18010	COG2826	transposase and inactivated derivatives, IS30 family
KXJ74_18030	COG0673	inositol 2-dehydrogenase activity