locus-tag	class	description
MRY16_00010	COG0592	DNA-directed DNA polymerase activity
MRY16_00020	COG0187	DNA topoisomerase II activity
MRY16_00030	COG0586	Pfam SNARE associated Golgi protein
MRY16_00035	COG0488	(ABC) transporter
MRY16_00070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MRY16_00075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MRY16_00120	COG1012	belongs to the aldehyde dehydrogenase family
MRY16_00125	COG0733	neurotransmitter:sodium symporter activity
MRY16_00160	COG0583	DNA-binding transcription factor activity
MRY16_00165	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_00170	COG2233	PERMEase
MRY16_00180	COG1309	transcriptional regulator
MRY16_00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRY16_00215	COG2814	Major facilitator Superfamily
MRY16_00220	COG0656	L-ascorbic acid biosynthetic process
MRY16_00225	COG0583	DNA-binding transcription factor activity
MRY16_00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRY16_00240	COG1064	alcohol dehydrogenase
MRY16_00245	COG2818	Glycosylase
MRY16_00255	COG0739	heme binding
MRY16_00270	COG5487	UPF0391 membrane protein
MRY16_00275	COG2983	Belongs to the UPF0260 family
MRY16_00280	COG2133	pyrroloquinoline quinone binding
MRY16_00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MRY16_00305	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MRY16_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MRY16_00320	COG1335	isochorismatase
MRY16_00335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MRY16_00345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MRY16_00350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MRY16_00355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MRY16_00375	COG0560	Phosphoserine phosphatase
MRY16_00375	COG3830	Belongs to the UPF0237 family
MRY16_00415	COG0583	DNA-binding transcription factor activity
MRY16_00450	COG0534	Mate efflux family protein
MRY16_00455	COG0436	Aminotransferase
MRY16_00465	COG2733	membrane
MRY16_00480	COG2918	glutathione biosynthetic process
MRY16_00525	COG3150	esterase
MRY16_00535	COG0534	Mate efflux family protein
MRY16_00570	COG1247	-acetyltransferase
MRY16_00620	COG1393	Belongs to the ArsC family
MRY16_00625	COG0708	Exodeoxyribonuclease III
MRY16_00655	COG0386	Belongs to the glutathione peroxidase family
MRY16_00660	COG0189	ligase activity
MRY16_00680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MRY16_00690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MRY16_00725	COG2119	membrane
MRY16_00730	COG4774	siderophore transport
MRY16_00735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRY16_00735	COG0426	domain, Protein
MRY16_00755	COG0259	pyridoxamine-phosphate oxidase activity
MRY16_00760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MRY16_00785	COG1902	pentaerythritol trinitrate reductase activity
MRY16_00790	COG1519	Transferase
MRY16_00795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MRY16_00800	COG0668	transmembrane transport
MRY16_00810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MRY16_00815	COG1335	isochorismatase
MRY16_00860	COG1309	transcriptional regulator
MRY16_00865	COG0604	alcohol dehydrogenase
MRY16_00865	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_00865	COG3321	synthase
MRY16_00875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MRY16_00885	COG2814	Major facilitator Superfamily
MRY16_00890	COG0629	single-stranded DNA binding
MRY16_00895	COG1113	amino acid transport
MRY16_00905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MRY16_00910	COG1012	belongs to the aldehyde dehydrogenase family
MRY16_00920	COG1335	isochorismatase
MRY16_00930	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
MRY16_01015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MRY16_01035	COG2329	Antibiotic biosynthesis monooxygenase
MRY16_01045	COG1396	sequence-specific DNA binding
MRY16_01050	COG0659	secondary active sulfate transmembrane transporter activity
MRY16_01070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MRY16_01100	COG0427	acetyl-CoA hydrolase
MRY16_01140	COG0477	Major facilitator Superfamily
MRY16_01145	COG0789	Transcriptional regulator
MRY16_01150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MRY16_01150	COG3320	Male sterility
MRY16_01155	COG4221	oxidoreductase activity
MRY16_01165	COG0488	(ABC) transporter
MRY16_01240	COG0833	amino acid
MRY16_01265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MRY16_01285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MRY16_01290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MRY16_01300	COG2226	methyltransferase
MRY16_01350	COG0069	glutamate synthase activity
MRY16_01350	COG0070	glutamate synthase
MRY16_01350	COG0067	glutamate synthase
MRY16_01355	COG0493	'glutamate synthase
MRY16_01365	COG1704	LemA family
MRY16_01370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MRY16_01405	COG3307	-O-antigen
MRY16_01425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MRY16_01435	COG0194	GDP metabolic process
MRY16_01440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MRY16_01480	COG0228	four-way junction DNA binding
MRY16_01485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MRY16_01495	COG0335	large ribosomal subunit rRNA binding
MRY16_01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MRY16_01505	COG5380	lipid catabolic process
MRY16_01510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MRY16_01530	COG5006	permease, DMT superfamily
MRY16_01535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MRY16_01540	COG0277	FAD linked oxidase domain protein
MRY16_01555	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MRY16_01560	COG2249	NAD(P)H dehydrogenase (quinone) activity
MRY16_01580	COG1289	transmembrane transporter activity
MRY16_01585	COG2032	superoxide dismutase activity
MRY16_01590	COG0628	permease
MRY16_01595	COG1192	Involved in chromosome partitioning
MRY16_01605	COG2226	methyltransferase
MRY16_01620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MRY16_01640	COG1404	Belongs to the peptidase S8 family
MRY16_01650	COG2072	flavoprotein involved in K transport
MRY16_01685	COG0471	metal ion transport
MRY16_01695	COG0617	tRNA 3'-terminal CCA addition
MRY16_01695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MRY16_01695	COG0517	IMP dehydrogenase activity
MRY16_01700	COG1983	PspC domain protein
MRY16_01710	COG1960	acyl-CoA dehydrogenase activity
MRY16_01730	COG0408	coproporphyrinogen oxidase activity
MRY16_01750	COG0513	Belongs to the DEAD box helicase family
MRY16_01755	COG1127	ABC transporter
MRY16_01760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MRY16_01765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MRY16_01770	COG2854	intermembrane phospholipid transfer
MRY16_01785	COG0598	Magnesium transport protein CorA
MRY16_01800	COG1040	competence protein
MRY16_01805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MRY16_01820	COG2937	Belongs to the GPAT DAPAT family
MRY16_01825	COG1946	Acyl-CoA thioesterase
MRY16_01830	COG1301	dicarboxylic acid transport
MRY16_01845	COG1959	2 iron, 2 sulfur cluster binding
MRY16_01855	COG0433	COG0433 Predicted ATPase
MRY16_01860	COG0626	cystathionine gamma-synthase activity
MRY16_01875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MRY16_01895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MRY16_01920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MRY16_01945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MRY16_01960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MRY16_02025	COG1960	acyl-CoA dehydrogenase activity
MRY16_02030	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MRY16_02065	COG0697	spore germination
MRY16_02080	COG0339	signal peptide processing
MRY16_02090	COG0557	exoribonuclease II activity
MRY16_02125	COG0179	Fumarylacetoacetate (FAA) hydrolase
MRY16_02145	COG1295	ribonuclease BN
MRY16_02175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MRY16_02200	COG2813	Specifically methylates the guanine in position
MRY16_02200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRY16_02210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MRY16_02220	COG4774	siderophore transport
MRY16_02230	COG0740	serine-type endopeptidase activity
MRY16_02250	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MRY16_02250	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MRY16_02260	COG0697	spore germination
MRY16_02265	COG0280	phosphate acetyltransferase
MRY16_02265	COG0857	belongs to the CobB CobQ family
MRY16_02270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MRY16_02280	COG2267	carboxylic ester hydrolase activity
MRY16_02295	COG0793	Belongs to the peptidase S41A family
MRY16_02320	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MRY16_02330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MRY16_02335	COG1408	metallophosphoesterase
MRY16_02345	COG2199	diguanylate cyclase activity
MRY16_02400	COG1607	acyl-coa hydrolase
MRY16_02405	COG1956	GAF domain-containing protein
MRY16_02420	COG1666	GTP binding
MRY16_02440	COG2350	Protein conserved in bacteria
MRY16_02450	COG0613	PHP domain protein
MRY16_02455	COG3781	membrane
MRY16_02460	COG2003	Belongs to the UPF0758 family
MRY16_02465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MRY16_02500	COG1162	GTPase activity
MRY16_02505	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MRY16_02525	COG1538	Outer membrane efflux protein
MRY16_02530	COG1136	(ABC) transporter
MRY16_02530	COG0577	efflux transmembrane transporter activity
MRY16_02535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRY16_02545	COG1466	dna polymerase III delta subunit
MRY16_02565	COG0028	Belongs to the TPP enzyme family
MRY16_02570	COG0440	acetolactate synthase activity
MRY16_02585	COG3243	poly(R)-hydroxyalkanoic acid synthase
MRY16_02595	COG0640	Transcriptional regulator
MRY16_02605	COG0798	PFAM Bile acid sodium symporter
MRY16_02610	COG0431	NADPH-dependent FMN reductase
MRY16_02625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MRY16_02635	COG0726	polysaccharide deacetylase
MRY16_02640	COG0084	hydrolase, TatD family'
MRY16_02660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MRY16_02670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MRY16_02750	COG2184	nucleotidyltransferase activity
MRY16_02760	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MRY16_02790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MRY16_02810	COG2814	Major facilitator Superfamily
MRY16_02820	COG0789	Transcriptional regulator
MRY16_02845	COG0300	oxidoreductase activity
MRY16_02850	COG0004	ammonium transporteR
MRY16_02865	COG3622	Belongs to the hyi family
MRY16_02870	COG2084	Dehydrogenase
MRY16_02875	COG1024	Enoyl-CoA hydratase
MRY16_02880	COG5002	protein histidine kinase activity
MRY16_02880	COG2205	protein histidine kinase activity
MRY16_02880	COG0784	Response regulator, receiver
MRY16_02900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MRY16_02915	COG3956	TIGRFAM MazG family protein
MRY16_02920	COG1555	photosystem II stabilization
MRY16_02925	COG0617	tRNA 3'-terminal CCA addition
MRY16_02930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MRY16_02955	COG3028	Belongs to the UPF0307 family
MRY16_02960	COG0318	PFAM AMP-dependent synthetase and ligase
MRY16_02980	COG0625	glutathione transferase activity
MRY16_02990	COG1238	metal cluster binding
MRY16_03025	COG0072	phenylalanine-tRNA ligase activity
MRY16_03050	COG0248	Ppx GppA phosphatase
MRY16_03060	COG0037	tRNA processing
MRY16_03075	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MRY16_03075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MRY16_03100	COG1764	response to oxidative stress
MRY16_03110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MRY16_03170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MRY16_03175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MRY16_03180	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MRY16_03245	COG1968	undecaprenyl-diphosphatase activity
MRY16_03270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MRY16_03280	COG2132	Multicopper oxidase
MRY16_03310	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MRY16_03315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MRY16_03365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MRY16_03380	COG1063	alcohol dehydrogenase
MRY16_03400	COG1309	transcriptional regulator
MRY16_03405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MRY16_03430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MRY16_03445	COG0745	RESPONSE REGULATOR receiver
MRY16_03450	COG2205	protein histidine kinase activity
MRY16_03460	COG3706	GGDEF domain
MRY16_03465	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRY16_03475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRY16_03475	COG0649	NAD binding
MRY16_03485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MRY16_03500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRY16_03515	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MRY16_03520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MRY16_03540	COG1278	Cold shock
MRY16_03545	COG0583	DNA-binding transcription factor activity
MRY16_03550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRY16_03565	COG0668	transmembrane transport
MRY16_03575	COG2081	HI0933 family
MRY16_03585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MRY16_03615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRY16_03625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MRY16_03625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MRY16_03655	COG0489	protein tyrosine kinase activity
MRY16_03660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MRY16_03715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MRY16_03735	COG0730	response to heat
MRY16_03745	COG1196	nuclear chromosome segregation
MRY16_03755	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MRY16_03770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MRY16_03775	COG0596	Alpha beta hydrolase
MRY16_03775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRY16_03775	COG2226	methyltransferase
MRY16_03790	COG4106	trans-aconitate 2-methyltransferase activity
MRY16_03835	COG4166	transmembrane transport
MRY16_03870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MRY16_03875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MRY16_03890	COG0009	L-threonylcarbamoyladenylate synthase
MRY16_03895	COG3101	peptidyl-lysine hydroxylation
MRY16_03900	COG1399	metal-binding, possibly nucleic acid-binding protein
MRY16_03905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MRY16_03925	COG1652	LysM domain
MRY16_03930	COG0351	phosphomethylpyrimidine kinase
MRY16_03930	COG0352	thiamine-phosphate diphosphorylase activity
MRY16_03930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MRY16_03940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MRY16_03975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MRY16_04005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MRY16_04030	COG0564	pseudouridine synthase activity
MRY16_04055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MRY16_04080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MRY16_04080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MRY16_04095	COG1981	membrane
MRY16_04115	COG0049	tRNA binding
MRY16_04125	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MRY16_04140	COG0456	acetyltransferase
MRY16_04150	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MRY16_04155	COG0500	methyltransferase
MRY16_04160	COG0492	ferredoxin-NADP+ reductase activity
MRY16_04165	COG1674	ftsk spoiiie
MRY16_04170	COG1280	lysine exporter protein (LysE YggA)
MRY16_04180	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MRY16_04190	COG0850	regulation of cytokinetic process
MRY16_04200	COG0204	Acyl-transferase
MRY16_04205	COG2885	chlorophyll binding
MRY16_04210	COG0210	DNA helicase
MRY16_04215	COG0756	dUTP diphosphatase activity
MRY16_04220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MRY16_04235	COG0121	glutamine amidotransferase
MRY16_04250	COG2914	Belongs to the UPF0125 (RnfH) family
MRY16_04255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MRY16_04285	COG0420	3'-5' exonuclease activity
MRY16_04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MRY16_04335	COG1566	PFAM secretion protein HlyD family protein
MRY16_04340	COG2814	Major facilitator Superfamily
MRY16_04350	COG0789	Transcriptional regulator
MRY16_04355	COG2217	Heavy metal translocating P-type atpase
MRY16_04365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MRY16_04390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MRY16_04395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MRY16_04405	COG1012	belongs to the aldehyde dehydrogenase family
MRY16_04420	COG0833	amino acid
MRY16_04425	COG3040	lipid binding
MRY16_04430	COG3046	protein related to deoxyribodipyrimidine photolyase
MRY16_04545	COG0725	ABC transporter, periplasmic molybdate-binding protein
MRY16_04550	COG4149	molybdate abc transporter
MRY16_04565	COG1230	cation diffusion facilitator family transporter
MRY16_04575	COG4521	taurine ABC transporter
MRY16_04580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MRY16_04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRY16_04590	COG2175	clavaminate synthase activity
MRY16_04595	COG0589	response to stress
MRY16_04615	COG0242	peptide deformylase activity
MRY16_04635	COG0306	phosphate transporter
MRY16_04650	COG1115	amino acid carrier protein
MRY16_04655	COG1113	amino acid transport
MRY16_04665	COG0019	diaminopimelate decarboxylase activity
MRY16_04670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MRY16_04680	COG1280	lysine exporter protein (LysE YggA)
MRY16_04745	COG1671	Belongs to the UPF0178 family
MRY16_04760	COG4591	ABC-type transport system involved in lipoprotein release permease component
MRY16_04765	COG1136	(ABC) transporter
MRY16_04770	COG0658	competence protein
MRY16_04770	COG2333	competence protein COMEC
MRY16_04780	COG0616	signal peptide processing
MRY16_04780	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MRY16_04790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MRY16_04800	COG0628	permease
MRY16_04805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MRY16_04835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MRY16_04855	COG0823	Involved in the tonB-independent uptake of proteins
MRY16_04875	COG0824	Thioesterase
MRY16_04910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MRY16_04910	COG0047	phosphoribosylformylglycinamidine synthase activity
MRY16_04915	COG2814	Major facilitator Superfamily
MRY16_04935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MRY16_04935	COG3323	Protein of unknown function (DUF1653)
MRY16_04940	COG0778	Nitroreductase
MRY16_04945	COG1024	Enoyl-CoA hydratase
MRY16_04950	COG1051	belongs to the nudix hydrolase family
MRY16_04950	COG1056	cytidyltransferase-related domain
MRY16_04960	COG0625	glutathione transferase activity
MRY16_04965	COG1942	4-Oxalocrotonate Tautomerase
MRY16_04985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MRY16_05000	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MRY16_05005	COG0602	queuosine metabolic process
MRY16_05020	COG0583	DNA-binding transcription factor activity
MRY16_05025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MRY16_05030	COG4208	sulfate ABC transporter
MRY16_05035	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MRY16_05045	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MRY16_05050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MRY16_05055	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MRY16_05070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MRY16_05080	COG0481	GTPase activity
MRY16_05095	COG0571	ribonuclease III activity
MRY16_05100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MRY16_05115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MRY16_05135	COG0436	Aminotransferase
MRY16_05160	COG0556	nucleotide-excision repair
MRY16_05215	COG0583	DNA-binding transcription factor activity
MRY16_05220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRY16_05225	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRY16_05230	COG1773	rubredoxin
MRY16_05240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MRY16_05250	COG0175	sulfate reduction
MRY16_05270	COG0222	ribosome binding
MRY16_05275	COG1253	flavin adenine dinucleotide binding
MRY16_05290	COG3015	lipoprotein NlpE involved in copper resistance
MRY16_05305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MRY16_05305	COG0517	IMP dehydrogenase activity
MRY16_05310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MRY16_05320	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MRY16_05325	COG1137	ATPase activity
MRY16_05330	COG1538	Outer membrane efflux protein
MRY16_05345	COG1739	Uncharacterized protein family UPF0029
MRY16_05370	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MRY16_05385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MRY16_05425	COG1840	ABC-type Fe3 transport system, periplasmic component
MRY16_05430	COG3842	ATPase activity
MRY16_05440	COG1253	flavin adenine dinucleotide binding
MRY16_05445	COG0772	Belongs to the SEDS family
MRY16_05465	COG5002	protein histidine kinase activity
MRY16_05480	COG2351	hydroxyisourate hydrolase activity
MRY16_05495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MRY16_05500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MRY16_05535	COG4783	chaperone-mediated protein folding
MRY16_05550	COG1610	YqeY-like protein
MRY16_05570	COG0697	spore germination
MRY16_05615	COG1414	Transcriptional regulator
MRY16_05620	COG2146	nitrite reductase [NAD(P)H] activity
MRY16_05635	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_05650	COG2271	Major facilitator Superfamily
MRY16_05665	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_05680	COG0028	Belongs to the TPP enzyme family
MRY16_05725	COG0482	sulfurtransferase activity
MRY16_05740	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MRY16_05745	COG1686	Belongs to the peptidase S11 family
MRY16_05770	COG0583	DNA-binding transcription factor activity
MRY16_05775	COG1067	ATP-dependent peptidase activity
MRY16_05810	COG1509	lysine 2,3-aminomutase activity
MRY16_05815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MRY16_05820	COG1966	Carbon starvation protein
MRY16_05825	COG2879	small protein
MRY16_05830	COG0714	Associated with various cellular activities
MRY16_05860	COG1741	Belongs to the pirin family
MRY16_05870	COG1902	pentaerythritol trinitrate reductase activity
MRY16_05870	COG0446	pyridine nucleotide-disulphide oxidoreductase
MRY16_05880	COG2207	Transcriptional regulator
MRY16_05895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRY16_05900	COG0183	Belongs to the thiolase family
MRY16_05905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MRY16_05910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MRY16_05920	COG4829	muconolactone delta-isomerase
MRY16_05925	COG4948	Mandelate Racemase Muconate Lactonizing
MRY16_05930	COG0543	2 iron, 2 sulfur cluster binding
MRY16_05930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MRY16_05935	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MRY16_05940	COG4638	Rieske (2fe-2S)
MRY16_05970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MRY16_05975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MRY16_05975	COG4451	ribulose bisphosphate carboxylase, small
MRY16_05980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MRY16_05985	COG1469	GTP cyclohydrolase I activity
MRY16_06000	COG0523	cobalamin synthesis protein
MRY16_06005	COG1960	acyl-CoA dehydrogenase activity
MRY16_06045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MRY16_06055	COG4106	trans-aconitate 2-methyltransferase activity
MRY16_06060	COG0642	Histidine kinase
MRY16_06065	COG0745	RESPONSE REGULATOR receiver
MRY16_06090	COG2985	domain, Protein
MRY16_06105	COG1414	Transcriptional regulator
MRY16_06110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MRY16_06115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MRY16_06120	COG0183	Belongs to the thiolase family
MRY16_06125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MRY16_06130	COG0596	Alpha beta hydrolase
MRY16_06135	COG2271	Major facilitator Superfamily
MRY16_06140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MRY16_06145	COG3485	protocatechuate 3,4-dioxygenase
MRY16_06150	COG3485	protocatechuate 3,4-dioxygenase
MRY16_06155	COG0710	3-dehydroquinate dehydratase activity
MRY16_06160	COG3420	alginic acid biosynthetic process
MRY16_06165	COG3659	wide pore channel activity
MRY16_06170	COG4993	Dehydrogenase
MRY16_06180	COG2351	hydroxyisourate hydrolase activity
MRY16_06185	COG2233	PERMEase
MRY16_06195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRY16_06200	COG2186	Transcriptional regulator
MRY16_06225	COG0583	DNA-binding transcription factor activity
MRY16_06235	COG2188	Transcriptional regulator
MRY16_06265	COG0010	Belongs to the arginase family
MRY16_06270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MRY16_06275	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_06290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRY16_06320	COG0243	molybdopterin cofactor binding
MRY16_06325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MRY16_06330	COG1309	transcriptional regulator
MRY16_06350	COG2072	flavoprotein involved in K transport
MRY16_06355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MRY16_06360	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MRY16_06365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MRY16_06370	COG4770	biotin carboxylase activity
MRY16_06375	COG0501	Belongs to the peptidase M48B family
MRY16_06385	COG1765	OsmC-like protein
MRY16_06435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MRY16_06455	COG3634	alkyl hydroperoxide reductase activity
MRY16_06475	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRY16_06495	COG1643	Atp-dependent helicase
MRY16_06510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MRY16_06515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRY16_06535	COG2951	lytic endotransglycosylase activity
MRY16_06540	COG0772	Belongs to the SEDS family
MRY16_06555	COG0842	Transport permease protein
MRY16_06560	COG1131	(ABC) transporter
MRY16_06565	COG0583	DNA-binding transcription factor activity
MRY16_06575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MRY16_06585	COG3659	wide pore channel activity
MRY16_06640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MRY16_06645	COG0826	peptidase U32
MRY16_06655	COG4682	membrane
MRY16_06670	COG2808	Putative FMN-binding domain
MRY16_06685	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MRY16_06690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRY16_06700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MRY16_06725	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MRY16_06755	COG0729	surface antigen
MRY16_06790	COG0471	metal ion transport
MRY16_06795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRY16_06805	COG3647	Membrane
MRY16_06810	COG2814	Major facilitator Superfamily
MRY16_06815	COG0583	DNA-binding transcription factor activity
MRY16_06840	COG1720	tRNA m6t6A37 methyltransferase activity
MRY16_06850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MRY16_06865	COG0642	Histidine kinase
MRY16_06875	COG0494	nUDIX hydrolase
MRY16_06885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MRY16_06890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MRY16_06895	COG3139	Protein of unknown function (DUF1315)
MRY16_06935	COG1960	acyl-CoA dehydrogenase activity
MRY16_06950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MRY16_06960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MRY16_06965	COG2195	Cleaves the N-terminal amino acid of tripeptides
MRY16_06985	COG1690	Belongs to the RtcB family
MRY16_06990	COG1234	tRNA 3'-trailer cleavage
MRY16_07000	COG4650	regulator
MRY16_07065	COG0513	Belongs to the DEAD box helicase family
MRY16_07075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRY16_07085	COG3178	'Phosphotransferase
MRY16_07090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MRY16_07100	COG1192	Involved in chromosome partitioning
MRY16_07105	COG1475	DNA binding
MRY16_07110	COG0811	peptide transport
MRY16_07120	COG1132	(ABC) transporter
MRY16_07125	COG1663	tetraacyldisaccharide 4'-kinase activity
MRY16_07145	COG0084	hydrolase, TatD family'
MRY16_07210	COG0776	regulation of translation
MRY16_07245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MRY16_07250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MRY16_07285	COG0024	Methionine aminopeptidase
MRY16_07290	COG0583	DNA-binding transcription factor activity
MRY16_07295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MRY16_07305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MRY16_07310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MRY16_07315	COG0517	IMP dehydrogenase activity
MRY16_07315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MRY16_07340	COG0552	protein localization to endoplasmic reticulum
MRY16_07350	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MRY16_07365	COG4890	Cyd operon protein YbgT
MRY16_07370	COG1294	oxidase, subunit
MRY16_07395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MRY16_07415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MRY16_07420	COG0569	domain protein
MRY16_07425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MRY16_07430	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MRY16_07455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MRY16_07465	COG0542	response to heat
MRY16_07475	COG0488	(ABC) transporter
MRY16_07480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MRY16_07485	COG2267	carboxylic ester hydrolase activity
MRY16_07495	COG1902	pentaerythritol trinitrate reductase activity
MRY16_07495	COG0446	pyridine nucleotide-disulphide oxidoreductase
MRY16_07535	COG0148	phosphopyruvate hydratase activity
MRY16_07540	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MRY16_07580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MRY16_07585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MRY16_07600	COG1802	Transcriptional regulator
MRY16_07610	COG2207	Transcriptional regulator
MRY16_07615	COG1063	alcohol dehydrogenase
MRY16_07625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MRY16_07645	COG1454	alcohol dehydrogenase
MRY16_07655	COG2814	Major facilitator Superfamily
MRY16_07660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MRY16_07665	COG0183	Belongs to the thiolase family
MRY16_07670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MRY16_07675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MRY16_07680	COG3135	benzoate transporter
MRY16_07685	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_07690	COG0543	2 iron, 2 sulfur cluster binding
MRY16_07690	COG0633	Ferredoxin
MRY16_07695	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MRY16_07700	COG4638	Rieske (2fe-2S)
MRY16_07710	COG4829	muconolactone delta-isomerase
MRY16_07715	COG4948	Mandelate Racemase Muconate Lactonizing
MRY16_07720	COG0583	DNA-binding transcription factor activity
MRY16_07730	COG1944	ATP diphosphatase activity
MRY16_07740	COG4221	oxidoreductase activity
MRY16_07755	COG0439	Biotin carboxylase
MRY16_07760	COG1196	nuclear chromosome segregation
MRY16_07765	COG0864	Transcriptional regulator
MRY16_07770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRY16_07780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRY16_07800	COG0583	DNA-binding transcription factor activity
MRY16_07810	COG4770	biotin carboxylase activity
MRY16_07815	COG1024	Enoyl-CoA hydratase
MRY16_07820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MRY16_07825	COG1960	acyl-CoA dehydrogenase activity
MRY16_07830	COG1309	transcriptional regulator
MRY16_07835	COG0318	PFAM AMP-dependent synthetase and ligase
MRY16_07850	COG2814	Major facilitator Superfamily
MRY16_07870	COG0583	DNA-binding transcription factor activity
MRY16_07895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRY16_07900	COG0730	response to heat
MRY16_07920	COG4628	conserved protein (DUF2132)
MRY16_07970	COG1401	restriction endodeoxyribonuclease activity
MRY16_07990	COG2249	NAD(P)H dehydrogenase (quinone) activity
MRY16_08000	COG3706	GGDEF domain
MRY16_08015	COG0133	tryptophan synthase activity
MRY16_08025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MRY16_08045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MRY16_08075	COG0537	adenosine 5'-monophosphoramidase activity
MRY16_08100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRY16_08120	COG0730	response to heat
MRY16_08135	COG4771	TonB-dependent receptor
MRY16_08150	COG0406	alpha-ribazole phosphatase activity
MRY16_08155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MRY16_08170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MRY16_08185	COG2223	nitrite transmembrane transporter activity
MRY16_08215	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MRY16_08230	COG1960	acyl-CoA dehydrogenase activity
MRY16_08235	COG1960	acyl-CoA dehydrogenase activity
MRY16_08240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRY16_08245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MRY16_08250	COG2207	Transcriptional regulator
MRY16_08255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRY16_08265	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRY16_08290	COG0575	Belongs to the CDS family
MRY16_08295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MRY16_08300	COG0233	cytoplasmic translational termination
MRY16_08315	COG3852	Histidine kinase
MRY16_08320	COG2204	response regulator
MRY16_08390	COG0697	spore germination
MRY16_08395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MRY16_08405	COG0303	'Molybdopterin
MRY16_08410	COG0315	cyclic pyranopterin monophosphate synthase activity
MRY16_08410	COG0521	Mo-molybdopterin cofactor biosynthetic process
MRY16_08425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MRY16_08430	COG0243	molybdopterin cofactor binding
MRY16_08445	COG0243	molybdopterin cofactor binding
MRY16_08450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRY16_08455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRY16_08455	COG2146	nitrite reductase [NAD(P)H] activity
MRY16_08460	COG2223	nitrite transmembrane transporter activity
MRY16_08470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRY16_08470	COG1116	anion transmembrane transporter activity
MRY16_08500	COG2814	Major facilitator Superfamily
MRY16_08505	COG1113	amino acid transport
MRY16_08515	COG0625	glutathione transferase activity
MRY16_08535	COG0069	glutamate synthase activity
MRY16_08570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MRY16_08575	COG1454	alcohol dehydrogenase
MRY16_08580	COG0824	Thioesterase
MRY16_08585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MRY16_08590	COG2850	peptidyl-arginine hydroxylation
MRY16_08635	COG3122	Protein conserved in bacteria
MRY16_08640	COG0668	transmembrane transport
MRY16_08655	COG1132	(ABC) transporter
MRY16_08675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MRY16_08685	COG0506	proline dehydrogenase activity
MRY16_08685	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MRY16_08685	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MRY16_08690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MRY16_08700	COG3698	Phosphodiester glycosidase
MRY16_08710	COG0590	tRNA wobble adenosine to inosine editing
MRY16_08715	COG3811	Belongs to the UPF0386 family
MRY16_08725	COG2353	YceI-like domain
MRY16_08735	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MRY16_08740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MRY16_08770	COG1278	Cold shock
MRY16_08790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MRY16_08790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MRY16_08815	COG3539	Fimbrial protein
MRY16_09005	COG4695	Portal protein
MRY16_09010	COG1802	Transcriptional regulator
MRY16_09010	COG4626	Terminase
MRY16_09030	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MRY16_09120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MRY16_09125	COG0753	catalase activity
MRY16_09130	COG1560	Kdo2-lipid A biosynthetic process
MRY16_09150	COG3772	lysozyme
MRY16_09155	COG0204	Acyl-transferase
MRY16_09190	COG1464	Belongs to the NlpA lipoprotein family
MRY16_09195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MRY16_09200	COG2011	ABC-type metal ion transport system permease component
MRY16_09205	COG0012	GTP binding
MRY16_09220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MRY16_09265	COG0386	Belongs to the glutathione peroxidase family
MRY16_09275	COG0436	Aminotransferase
MRY16_09310	COG2267	carboxylic ester hydrolase activity
MRY16_09315	COG3634	alkyl hydroperoxide reductase activity
MRY16_09365	COG1286	toxin biosynthetic process
MRY16_09395	COG0778	Nitroreductase
MRY16_09420	COG0424	maF-like protein
MRY16_09455	COG2030	dehydratase
MRY16_09465	COG0183	Belongs to the thiolase family
MRY16_09480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MRY16_09485	COG0702	epimerase
MRY16_09490	COG0268	Binds directly to 16S ribosomal RNA
MRY16_09510	COG1011	Hydrolase
MRY16_09515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MRY16_09525	COG2137	regulation of response to DNA damage stimulus
MRY16_09540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRY16_09570	COG0822	iron-sulfur transferase activity
MRY16_09575	COG0316	Belongs to the HesB IscA family
MRY16_09605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MRY16_09620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MRY16_09630	COG3135	benzoate transporter
MRY16_09635	COG0475	glutathione-regulated potassium exporter activity
MRY16_09635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MRY16_09650	COG1760	l-serine dehydratase
MRY16_09655	COG0308	aminopeptidase N
MRY16_09690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MRY16_09700	COG0531	amino acid
MRY16_09705	COG4303	Ethanolamine ammonia lyase large subunit
MRY16_09710	COG4302	ethanolamine ammonia-lyase activity
MRY16_09715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MRY16_09720	COG0519	Catalyzes the synthesis of GMP from XMP
MRY16_09720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MRY16_09725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MRY16_09735	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MRY16_09740	COG0778	Nitroreductase
MRY16_09745	COG0697	spore germination
MRY16_09750	COG1923	regulation of RNA biosynthetic process
MRY16_09760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MRY16_09765	COG0802	atpase or kinase
MRY16_09800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MRY16_09825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MRY16_09830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MRY16_09835	COG1845	cytochrome c oxidase, subunit III
MRY16_09840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MRY16_09875	COG0305	Participates in initiation and elongation during chromosome replication
MRY16_09880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MRY16_09890	COG1305	Transglutaminase-like
MRY16_09900	COG2308	Evidence 4 Homologs of previously reported genes of
MRY16_09915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MRY16_09935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MRY16_09945	COG0527	aspartate kinase activity
MRY16_09955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MRY16_09970	COG3038	cytochrome b561
MRY16_09975	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MRY16_09980	COG2252	PERMEase
MRY16_10035	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MRY16_10040	COG0138	bifunctional purine biosynthesis protein purh
MRY16_10045	COG0151	Belongs to the GarS family
MRY16_10055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MRY16_10060	COG2011	ABC-type metal ion transport system permease component
MRY16_10085	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MRY16_10095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MRY16_10105	COG0280	phosphate acetyltransferase
MRY16_10105	COG0281	malic enzyme
MRY16_10120	COG0052	Belongs to the universal ribosomal protein uS2 family
MRY16_10125	COG0024	Methionine aminopeptidase
MRY16_10135	COG2223	nitrite transmembrane transporter activity
MRY16_10145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MRY16_10150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MRY16_10155	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MRY16_10190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MRY16_10195	COG3161	chorismate lyase activity
MRY16_10200	COG0174	glutamine synthetase
MRY16_10205	COG0512	Glutamine amidotransferase of anthranilate synthase
MRY16_10210	COG1823	symporter activity
MRY16_10215	COG3217	Mosc domain protein beta barrel domain protein
MRY16_10215	COG0633	Ferredoxin
MRY16_10240	COG0302	gtp cyclohydrolase
MRY16_10260	COG3739	integral membrane protein
MRY16_10275	COG3706	GGDEF domain
MRY16_10275	COG2203	Gaf domain
MRY16_10275	COG5001	Diguanylate cyclase
MRY16_10275	COG4251	negative regulation of phosphorylation
MRY16_10285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MRY16_10300	COG4172	Belongs to the ABC transporter superfamily
MRY16_10305	COG4239	(ABC) transporter, permease
MRY16_10310	COG4174	ABC transporter (Permease)
MRY16_10315	COG4166	transmembrane transport
MRY16_10320	COG0741	lytic transglycosylase activity
MRY16_10320	COG1388	LysM domain
MRY16_10325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MRY16_10380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRY16_10385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MRY16_10390	COG0006	proline dipeptidase activity
MRY16_10425	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MRY16_10435	COG0714	Associated with various cellular activities
MRY16_10440	COG3831	ATPase activity
MRY16_10455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MRY16_10470	COG3384	dioxygenase
MRY16_10480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MRY16_10485	COG2878	Part of a membrane complex involved in electron transport
MRY16_10490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MRY16_10515	COG0768	penicillin binding
MRY16_10520	COG0742	ribosomal rna small subunit methyltransferase
MRY16_10545	COG0616	signal peptide processing
MRY16_10550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MRY16_10560	COG0573	inorganic phosphate transmembrane transporter activity
MRY16_10575	COG0076	glutamate decarboxylase activity
MRY16_10580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MRY16_10590	COG1309	transcriptional regulator
MRY16_10610	COG1309	transcriptional regulator
MRY16_10620	COG0783	Belongs to the Dps family
MRY16_10630	COG0564	pseudouridine synthase activity
MRY16_10640	COG0352	thiamine-phosphate diphosphorylase activity
MRY16_10670	COG0612	Peptidase, M16
MRY16_10685	COG1187	pseudouridine synthase activity
MRY16_10705	COG1686	Belongs to the peptidase S11 family
MRY16_10710	COG1252	NADH dehydrogenase
MRY16_10720	COG0415	Belongs to the DNA photolyase family
MRY16_10735	COG1215	transferase activity, transferring glycosyl groups
MRY16_10770	COG1271	oxidase subunit
MRY16_10775	COG1294	oxidase, subunit
MRY16_10780	COG2070	2-Nitropropane dioxygenase
MRY16_10795	COG0457	Tetratricopeptide repeat
MRY16_10795	COG0705	Rhomboid family
MRY16_10800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MRY16_10805	COG4181	ATPase activity
MRY16_10815	COG0288	reversible hydration of carbon dioxide
MRY16_10830	COG4771	TonB-dependent receptor
MRY16_10855	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MRY16_10895	COG1597	lipid kinase activity
MRY16_10900	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MRY16_10915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MRY16_10925	COG2388	GCN5-related N-acetyl-transferase
MRY16_10965	COG1215	transferase activity, transferring glycosyl groups
MRY16_10970	COG0726	polysaccharide deacetylase
MRY16_10970	COG1649	PFAM Uncharacterised BCR, COG1649
MRY16_10985	COG4681	YaeQ
MRY16_10990	COG0523	cobalamin synthesis protein
MRY16_11000	COG1607	acyl-coa hydrolase
MRY16_11015	COG0583	DNA-binding transcription factor activity
MRY16_11020	COG1301	dicarboxylic acid transport
MRY16_11030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MRY16_11035	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MRY16_11050	COG0741	lytic transglycosylase activity
MRY16_11055	COG0501	Belongs to the peptidase M48B family
MRY16_11065	COG2239	Acts as a magnesium transporter
MRY16_11075	COG2194	sulfuric ester hydrolase activity
MRY16_11080	COG0584	glycerophosphoryl diester phosphodiesterase
MRY16_11085	COG3201	nicotinamide mononucleotide transporter
MRY16_11105	COG2304	oxidoreductase activity
MRY16_11110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MRY16_11115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MRY16_11140	COG0505	Belongs to the CarA family
MRY16_11160	COG0589	response to stress
MRY16_11200	COG2321	neutral zinc metallopeptidase
MRY16_11205	COG2354	Protein conserved in bacteria
MRY16_11215	COG1585	Membrane protein implicated in regulation of membrane protease activity
MRY16_11220	COG2268	Band 7 protein
MRY16_11230	COG1215	transferase activity, transferring glycosyl groups
MRY16_11235	COG1649	PFAM Uncharacterised BCR, COG1649
MRY16_11235	COG0726	polysaccharide deacetylase
MRY16_11255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MRY16_11270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MRY16_11275	COG1053	succinate dehydrogenase
MRY16_11280	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MRY16_11285	COG2009	succinate dehydrogenase
MRY16_11310	COG1054	Belongs to the UPF0176 family
MRY16_11315	COG0586	Pfam SNARE associated Golgi protein
MRY16_11320	COG0500	methyltransferase
MRY16_11330	COG0583	DNA-binding transcription factor activity
MRY16_11365	COG0321	lipoyl(octanoyl) transferase activity
MRY16_11380	COG0531	amino acid
MRY16_11395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MRY16_11400	COG1648	precorrin-2 dehydrogenase activity
MRY16_11400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MRY16_11415	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MRY16_11445	COG0671	phosphoesterase, PA-phosphatase related
MRY16_11450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MRY16_11460	COG1538	Outer membrane efflux protein
MRY16_11465	COG0393	Putative heavy-metal-binding
MRY16_11470	COG0393	Putative heavy-metal-binding
MRY16_11480	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_11495	COG0525	valine-tRNA ligase activity
MRY16_11515	COG0004	ammonium transporteR
MRY16_11530	COG0642	Histidine kinase
MRY16_11535	COG0745	RESPONSE REGULATOR receiver
MRY16_11540	COG2194	sulfuric ester hydrolase activity
MRY16_11560	COG1752	Esterase of the alpha-beta hydrolase superfamily
MRY16_11575	COG2814	Major facilitator Superfamily
MRY16_11580	COG0142	geranyltranstransferase activity
MRY16_11590	COG1113	amino acid transport
MRY16_11605	COG0174	glutamine synthetase
MRY16_11610	COG0671	phosphoesterase, PA-phosphatase related
MRY16_11620	COG2851	Citrate transporter
MRY16_11630	COG0745	RESPONSE REGULATOR receiver
MRY16_11635	COG2205	protein histidine kinase activity
MRY16_11640	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MRY16_11645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MRY16_11650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MRY16_11675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MRY16_11685	COG1530	ribonuclease E activity
MRY16_11690	COG0424	maF-like protein
MRY16_11700	COG1792	Involved in formation and maintenance of cell shape
MRY16_11705	COG1077	Cell shape determining protein MreB Mrl
MRY16_11710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MRY16_11720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MRY16_11775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MRY16_11780	COG1752	Esterase of the alpha-beta hydrolase superfamily
MRY16_11785	COG1115	amino acid carrier protein
MRY16_11790	COG0786	glutamate:sodium symporter activity
MRY16_11805	COG2814	Major facilitator Superfamily
MRY16_11810	COG1289	transmembrane transporter activity
MRY16_11820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MRY16_11865	COG1376	ErfK ybiS ycfS ynhG family protein
MRY16_11870	COG2832	Protein of unknown function (DUF454)
MRY16_11880	COG5510	response to toxic substance
MRY16_11895	COG0643	Histidine kinase
MRY16_11895	COG2198	Histidine kinase
MRY16_11895	COG0643	Histidine kinase
MRY16_11895	COG2198	Histidine kinase
MRY16_11900	COG0840	transmembrane signaling receptor activity
MRY16_11930	COG3422	double-strand break repair
MRY16_11935	COG2824	Alkylphosphonate utilization operon protein PhnA
MRY16_11940	COG3189	MarR family transcriptional regulator
MRY16_11950	COG0354	folic acid binding
MRY16_11960	COG4772	TonB-dependent receptor
MRY16_11970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MRY16_11980	COG1970	mechanosensitive ion channel activity
MRY16_11985	COG1217	gtp-binding protein TYPA
MRY16_11990	COG2233	PERMEase
MRY16_12000	COG0833	amino acid
MRY16_12005	COG1690	Belongs to the RtcB family
MRY16_12015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MRY16_12015	COG2885	chlorophyll binding
MRY16_12025	COG0183	Belongs to the thiolase family
MRY16_12045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MRY16_12060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MRY16_12065	COG2207	Transcriptional regulator
MRY16_12080	COG0183	Belongs to the thiolase family
MRY16_12115	COG1272	protein, Hemolysin III
MRY16_12120	COG0477	Major facilitator Superfamily
MRY16_12140	COG0450	alkyl hydroperoxide reductase
MRY16_12165	COG0285	dihydrofolate synthase activity
MRY16_12220	COG4206	TonB-dependent receptor
MRY16_12225	COG2096	Adenosyltransferase
MRY16_12245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MRY16_12260	COG0745	RESPONSE REGULATOR receiver
MRY16_12265	COG2205	protein histidine kinase activity
MRY16_12275	COG1960	acyl-CoA dehydrogenase activity
MRY16_12280	COG1960	acyl-CoA dehydrogenase activity
MRY16_12350	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MRY16_12380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MRY16_12380	COG2755	lipolytic protein G-D-S-L family
MRY16_12395	COG0438	transferase activity, transferring glycosyl groups
MRY16_12405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MRY16_12415	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MRY16_12420	COG0784	Response regulator, receiver
MRY16_12420	COG2205	protein histidine kinase activity
MRY16_12430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MRY16_12450	COG1862	Preprotein translocase
MRY16_12530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MRY16_12535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MRY16_12540	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MRY16_12555	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MRY16_12560	COG0625	glutathione transferase activity
MRY16_12565	COG2969	positive regulation of protein catabolic process
MRY16_12620	COG1960	acyl-CoA dehydrogenase activity
MRY16_12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MRY16_12640	COG1309	transcriptional regulator
MRY16_12650	COG1960	acyl-CoA dehydrogenase activity
MRY16_12655	COG1960	acyl-CoA dehydrogenase activity
MRY16_12700	COG1183	phosphatidylcholine synthase activity
MRY16_12705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MRY16_12735	COG0739	heme binding
MRY16_12735	COG0741	lytic transglycosylase activity
MRY16_12735	COG1196	nuclear chromosome segregation
MRY16_12745	COG1702	phosphate starvation-inducible protein PhoH
MRY16_12760	COG4773	Receptor
MRY16_12825	COG0788	formyltetrahydrofolate deformylase activity
MRY16_12850	COG4651	solute:proton antiporter activity
MRY16_12850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MRY16_12870	COG0724	RNA recognition motif
MRY16_12875	COG0210	DNA helicase
MRY16_12905	COG1733	regulation of RNA biosynthetic process
MRY16_12910	COG0604	alcohol dehydrogenase
MRY16_12915	COG2900	Belongs to the SlyX family
MRY16_12920	COG0488	(ABC) transporter
MRY16_12930	COG1560	Kdo2-lipid A biosynthetic process
MRY16_13005	COG0473	3-isopropylmalate dehydrogenase activity
MRY16_13030	COG0583	DNA-binding transcription factor activity
MRY16_13055	COG0494	nUDIX hydrolase
MRY16_13075	COG3011	Protein conserved in bacteria
MRY16_13090	COG0583	DNA-binding transcription factor activity
MRY16_13115	COG1530	ribonuclease E activity
MRY16_13120	COG0318	PFAM AMP-dependent synthetase and ligase
MRY16_13140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MRY16_13150	COG0534	Mate efflux family protein
MRY16_13155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MRY16_13185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MRY16_13200	COG0493	'glutamate synthase
MRY16_13200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MRY16_13210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MRY16_13215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MRY16_13230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MRY16_13240	COG0644	oxidoreductase
MRY16_13240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MRY16_13250	COG1595	DNA-templated transcription, initiation
MRY16_13260	COG3220	belongs to the UPF0276 family
MRY16_13275	COG1279	arginine transmembrane transporter activity
MRY16_13280	COG0425	Belongs to the sulfur carrier protein TusA family
MRY16_13285	COG4535	Mg2 and Co2 transporter CorC
MRY16_13310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MRY16_13320	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MRY16_13325	COG0484	heat shock protein binding
MRY16_13330	COG0789	Transcriptional regulator
MRY16_13335	COG0598	Magnesium transport protein CorA
MRY16_13340	COG1185	polyribonucleotide nucleotidyltransferase activity
MRY16_13345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MRY16_13350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MRY16_13355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MRY16_13360	COG1074	ATP-dependent DNA helicase activity
MRY16_13365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MRY16_13395	COG2226	methyltransferase
MRY16_13405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MRY16_13420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MRY16_13435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MRY16_13435	COG2111	Na H antiporter
MRY16_13440	COG1006	Multisubunit Na H antiporter MnhC subunit
MRY16_13445	COG0651	ATP synthesis coupled electron transport
MRY16_13450	COG1863	multisubunit Na H antiporter MnhE subunit
MRY16_13455	COG2212	antiporter activity
MRY16_13460	COG1320	monovalent cation:proton antiporter activity
MRY16_13465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MRY16_13475	COG0195	Participates in both transcription termination and antitermination
MRY16_13525	COG0237	dephospho-CoA kinase activity
MRY16_13535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MRY16_13545	COG0497	DNA recombination
MRY16_13555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MRY16_13580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MRY16_13610	COG3706	GGDEF domain
MRY16_13645	COG1132	(ABC) transporter
MRY16_13655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MRY16_13675	COG0326	Molecular chaperone. Has ATPase activity
MRY16_13690	COG2056	Na+-H+ antiporter family
MRY16_13735	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MRY16_13755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MRY16_13785	COG0546	phosphoglycolate phosphatase activity
MRY16_13790	COG1716	ATPase activity
MRY16_13835	COG0181	hydroxymethylbilane synthase activity
MRY16_13845	COG3275	phosphorelay sensor kinase activity
MRY16_13885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MRY16_13890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MRY16_13895	COG0772	Belongs to the SEDS family
MRY16_13920	COG4974	Belongs to the 'phage' integrase family
MRY16_13935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MRY16_13955	COG2197	response regulator
MRY16_13970	COG0793	Belongs to the peptidase S41A family
MRY16_13975	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MRY16_13980	COG0795	lipopolysaccharide-transporting ATPase activity
MRY16_13985	COG0795	lipopolysaccharide-transporting ATPase activity
MRY16_14020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MRY16_14020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MRY16_14030	COG0004	ammonium transporteR
MRY16_14035	COG0347	Belongs to the P(II) protein family
MRY16_14065	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MRY16_14080	COG0318	PFAM AMP-dependent synthetase and ligase
MRY16_14090	COG2860	membrane
MRY16_14100	COG1253	flavin adenine dinucleotide binding
MRY16_14115	COG2814	Major facilitator Superfamily
MRY16_14130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MRY16_14135	COG0745	RESPONSE REGULATOR receiver
MRY16_14145	COG2205	protein histidine kinase activity
MRY16_14150	COG4452	Inner membrane protein CreD
MRY16_14175	COG2814	Major facilitator Superfamily
MRY16_14195	COG0655	NAD(P)H dehydrogenase (quinone) activity
MRY16_14215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MRY16_14250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MRY16_14270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MRY16_14275	COG3162	membrane
MRY16_14280	COG2205	protein histidine kinase activity
MRY16_14280	COG0784	Response regulator, receiver
MRY16_14305	COG1652	LysM domain
MRY16_14310	COG0758	DNA mediated transformation
MRY16_14325	COG1309	transcriptional regulator
MRY16_14340	COG0386	Belongs to the glutathione peroxidase family
MRY16_14355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MRY16_14395	COG0803	Belongs to the bacterial solute-binding protein 9 family
MRY16_14405	COG1121	(ABC) transporter
MRY16_14410	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MRY16_14420	COG2837	iron assimilation
MRY16_14425	COG0281	malic enzyme
MRY16_14455	COG1715	Restriction endonuclease
MRY16_14460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MRY16_14460	COG0519	Catalyzes the synthesis of GMP from XMP
MRY16_14465	COG4399	Belongs to the UPF0754 family
MRY16_14475	COG2259	Doxx family
MRY16_14480	COG0586	Pfam SNARE associated Golgi protein
MRY16_14495	COG1192	Involved in chromosome partitioning
MRY16_14505	COG0271	Belongs to the BolA IbaG family
MRY16_14520	COG0477	Major facilitator Superfamily
MRY16_14525	COG1024	Enoyl-CoA hydratase
MRY16_14530	COG1024	Enoyl-CoA hydratase
MRY16_14535	COG1960	acyl-CoA dehydrogenase activity
MRY16_14540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MRY16_14560	COG1113	amino acid transport
MRY16_14565	COG0251	oxidation-reduction process
MRY16_14600	COG0564	pseudouridine synthase activity
MRY16_14650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MRY16_14665	COG1802	Transcriptional regulator
MRY16_14670	COG1448	Aminotransferase
MRY16_14675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MRY16_14690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MRY16_14705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MRY16_14745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MRY16_14750	COG1045	serine acetyltransferase
MRY16_14755	COG2089	acid synthase
MRY16_14760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MRY16_14765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MRY16_14775	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MRY16_14780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MRY16_14805	COG0545	Peptidyl-prolyl cis-trans isomerase
MRY16_14810	COG0728	peptidoglycan biosynthetic process
MRY16_14815	COG3023	N-Acetylmuramoyl-L-alanine amidase
MRY16_14830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MRY16_14865	COG0546	phosphoglycolate phosphatase activity
MRY16_14870	COG1028	Short-chain dehydrogenase reductase Sdr
MRY16_14880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MRY16_14880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MRY16_14885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRY16_14890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MRY16_14895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MRY16_14900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MRY16_14905	COG1116	anion transmembrane transporter activity
MRY16_14910	COG1309	transcriptional regulator
MRY16_14925	COG0196	riboflavin kinase activity
MRY16_14930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MRY16_14940	COG1047	Peptidyl-prolyl cis-trans
MRY16_14945	COG0431	NADPH-dependent FMN reductase
MRY16_14975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MRY16_14980	COG0657	acetylesterase activity
MRY16_14995	COG0583	DNA-binding transcription factor activity
MRY16_15005	COG0443	Heat shock 70 kDa protein
MRY16_15010	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MRY16_15035	COG2951	lytic endotransglycosylase activity
MRY16_15040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MRY16_15055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MRY16_15075	COG1960	acyl-CoA dehydrogenase activity
MRY16_15080	COG0583	DNA-binding transcription factor activity
MRY16_15090	COG0861	Integral membrane protein TerC family
MRY16_15100	COG0754	glutathionylspermidine amidase activity
MRY16_15110	COG0402	S-adenosylhomocysteine deaminase activity
MRY16_15140	COG0706	membrane insertase activity
