locus-tag	class	description
CDG57_00020	COG1660	Displays ATPase and GTPase activities
CDG57_00030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG57_00040	COG2026	Addiction module toxin, RelE StbE family
CDG57_00050	COG3316	Transposase and inactivated derivatives
CDG57_00085	COG3173	Aminoglycoside phosphotransferase
CDG57_00125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDG57_00135	COG2026	Addiction module toxin, RelE StbE family
CDG57_00160	COG1192	Involved in chromosome partitioning
CDG57_00250	COG0592	DNA-directed DNA polymerase activity
CDG57_00260	COG0187	DNA topoisomerase II activity
CDG57_00270	COG0586	Pfam SNARE associated Golgi protein
CDG57_00275	COG0488	(ABC) transporter
CDG57_00310	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDG57_00315	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDG57_00360	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_00365	COG0733	neurotransmitter:sodium symporter activity
CDG57_00400	COG0583	DNA-binding transcription factor activity
CDG57_00415	COG2233	PERMEase
CDG57_00425	COG1309	transcriptional regulator
CDG57_00430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_00460	COG2814	Major facilitator Superfamily
CDG57_00470	COG0583	DNA-binding transcription factor activity
CDG57_00480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDG57_00485	COG1064	alcohol dehydrogenase
CDG57_00490	COG2818	Glycosylase
CDG57_00500	COG0739	heme binding
CDG57_00515	COG5487	UPF0391 membrane protein
CDG57_00520	COG2983	Belongs to the UPF0260 family
CDG57_00525	COG2133	pyrroloquinoline quinone binding
CDG57_00535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDG57_00555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDG57_00565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDG57_00570	COG1335	isochorismatase
CDG57_00645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDG57_00695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDG57_00705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDG57_00710	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDG57_00715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDG57_00735	COG3830	Belongs to the UPF0237 family
CDG57_00735	COG0560	Phosphoserine phosphatase
CDG57_00815	COG0534	Mate efflux family protein
CDG57_00820	COG0436	Aminotransferase
CDG57_00830	COG2733	membrane
CDG57_00845	COG2918	glutathione biosynthetic process
CDG57_00855	COG3501	Rhs element vgr protein
CDG57_00865	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_00895	COG1324	tolerance protein
CDG57_00900	COG0673	inositol 2-dehydrogenase activity
CDG57_00920	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_00930	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_01005	COG3150	esterase
CDG57_01045	COG0410	ABC transporter
CDG57_01055	COG0456	acetyltransferase
CDG57_01105	COG1393	Belongs to the ArsC family
CDG57_01110	COG0708	Exodeoxyribonuclease III
CDG57_01140	COG0386	Belongs to the glutathione peroxidase family
CDG57_01145	COG0189	ligase activity
CDG57_01165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDG57_01175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDG57_01215	COG2119	membrane
CDG57_01220	COG4774	siderophore transport
CDG57_01225	COG0426	domain, Protein
CDG57_01225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_01245	COG0259	pyridoxamine-phosphate oxidase activity
CDG57_01250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDG57_01275	COG1902	pentaerythritol trinitrate reductase activity
CDG57_01280	COG1519	Transferase
CDG57_01285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG57_01290	COG0668	transmembrane transport
CDG57_01300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG57_01305	COG1335	isochorismatase
CDG57_01335	COG3706	GGDEF domain
CDG57_01350	COG1309	transcriptional regulator
CDG57_01355	COG0604	alcohol dehydrogenase
CDG57_01355	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_01355	COG3321	synthase
CDG57_01365	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG57_01380	COG2814	Major facilitator Superfamily
CDG57_01385	COG0629	single-stranded DNA binding
CDG57_01400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG57_01405	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_01415	COG1335	isochorismatase
CDG57_01425	COG3293	Transposase
CDG57_01430	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDG57_01500	COG0582	viral genome integration into host DNA
CDG57_01545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDG57_01565	COG2329	Antibiotic biosynthesis monooxygenase
CDG57_01580	COG0659	secondary active sulfate transmembrane transporter activity
CDG57_01600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDG57_01630	COG0427	acetyl-CoA hydrolase
CDG57_01635	COG2205	protein histidine kinase activity
CDG57_01640	COG0745	RESPONSE REGULATOR receiver
CDG57_01685	COG0477	Major facilitator Superfamily
CDG57_01690	COG0789	Transcriptional regulator
CDG57_01695	COG3320	Male sterility
CDG57_01695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDG57_01700	COG4221	oxidoreductase activity
CDG57_01710	COG0488	(ABC) transporter
CDG57_01785	COG0833	amino acid
CDG57_01810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG57_01830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDG57_01835	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDG57_01845	COG2226	methyltransferase
CDG57_01895	COG0069	glutamate synthase activity
CDG57_01895	COG0070	glutamate synthase
CDG57_01895	COG0067	glutamate synthase
CDG57_01900	COG0493	'glutamate synthase
CDG57_01905	COG1704	LemA family
CDG57_01910	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDG57_01920	COG4969	Belongs to the N-Me-Phe pilin family
CDG57_01935	COG3307	-O-antigen
CDG57_01955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_01965	COG0194	GDP metabolic process
CDG57_01970	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDG57_01975	COG4968	Prepilin-type N-terminal cleavage methylation domain
CDG57_02010	COG0228	four-way junction DNA binding
CDG57_02015	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDG57_02025	COG0335	large ribosomal subunit rRNA binding
CDG57_02030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDG57_02035	COG5380	lipid catabolic process
CDG57_02040	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDG57_02060	COG5006	permease, DMT superfamily
CDG57_02065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDG57_02070	COG0277	FAD linked oxidase domain protein
CDG57_02085	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CDG57_02090	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG57_02110	COG1289	transmembrane transporter activity
CDG57_02115	COG2032	superoxide dismutase activity
CDG57_02120	COG0628	permease
CDG57_02125	COG1192	Involved in chromosome partitioning
CDG57_02135	COG2226	methyltransferase
CDG57_02150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG57_02200	COG0471	metal ion transport
CDG57_02215	COG1983	PspC domain protein
CDG57_02225	COG1960	acyl-CoA dehydrogenase activity
CDG57_02275	COG1127	ABC transporter
CDG57_02280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDG57_02285	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CDG57_02290	COG2854	intermembrane phospholipid transfer
CDG57_02310	COG0598	Magnesium transport protein CorA
CDG57_02320	COG0494	nUDIX hydrolase
CDG57_02325	COG1040	competence protein
CDG57_02330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDG57_02345	COG2937	Belongs to the GPAT DAPAT family
CDG57_02350	COG1946	Acyl-CoA thioesterase
CDG57_02355	COG1301	dicarboxylic acid transport
CDG57_02370	COG1959	2 iron, 2 sulfur cluster binding
CDG57_02375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG57_02375	COG1017	nitric oxide dioxygenase activity
CDG57_02380	COG0433	COG0433 Predicted ATPase
CDG57_02385	COG0626	cystathionine gamma-synthase activity
CDG57_02400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDG57_02420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDG57_02445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDG57_02470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDG57_02485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDG57_02505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDG57_02515	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDG57_02530	COG0203	ribosomal protein L17
CDG57_02550	COG1960	acyl-CoA dehydrogenase activity
CDG57_02555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CDG57_02605	COG0339	signal peptide processing
CDG57_02615	COG0557	exoribonuclease II activity
CDG57_02655	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDG57_02675	COG1295	ribonuclease BN
CDG57_02710	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDG57_02735	COG2813	Specifically methylates the guanine in position
CDG57_02735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_02745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDG57_02755	COG4774	siderophore transport
CDG57_02765	COG0740	serine-type endopeptidase activity
CDG57_02785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG57_02785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CDG57_02800	COG0280	phosphate acetyltransferase
CDG57_02800	COG0857	belongs to the CobB CobQ family
CDG57_02805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDG57_02830	COG0793	Belongs to the peptidase S41A family
CDG57_02855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDG57_02865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDG57_02870	COG1408	metallophosphoesterase
CDG57_02880	COG2199	diguanylate cyclase activity
CDG57_02935	COG1960	acyl-CoA dehydrogenase activity
CDG57_02940	COG1960	acyl-CoA dehydrogenase activity
CDG57_02950	COG1309	transcriptional regulator
CDG57_02965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG57_02970	COG1960	acyl-CoA dehydrogenase activity
CDG57_03025	COG2969	positive regulation of protein catabolic process
CDG57_03030	COG0625	glutathione transferase activity
CDG57_03035	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDG57_03040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDG57_03050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDG57_03055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDG57_03060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDG57_03140	COG1862	Preprotein translocase
CDG57_03160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDG57_03195	COG2205	protein histidine kinase activity
CDG57_03195	COG0784	Response regulator, receiver
CDG57_03200	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CDG57_03210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDG57_03220	COG0438	transferase activity, transferring glycosyl groups
CDG57_03265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDG57_03300	COG3223	Belongs to the PsiE family
CDG57_03305	COG1960	acyl-CoA dehydrogenase activity
CDG57_03310	COG1960	acyl-CoA dehydrogenase activity
CDG57_03320	COG2205	protein histidine kinase activity
CDG57_03325	COG0745	RESPONSE REGULATOR receiver
CDG57_03340	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDG57_03360	COG2096	Adenosyltransferase
CDG57_03365	COG4206	TonB-dependent receptor
CDG57_03375	COG0133	tryptophan synthase activity
CDG57_03420	COG0285	dihydrofolate synthase activity
CDG57_03445	COG0450	alkyl hydroperoxide reductase
CDG57_03470	COG0477	Major facilitator Superfamily
CDG57_03475	COG1272	protein, Hemolysin III
CDG57_03485	COG2153	protein acetylation
CDG57_03510	COG0183	Belongs to the thiolase family
CDG57_03525	COG2207	Transcriptional regulator
CDG57_03530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CDG57_03545	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_03565	COG0183	Belongs to the thiolase family
CDG57_03575	COG2885	chlorophyll binding
CDG57_03575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CDG57_03580	COG1690	Belongs to the RtcB family
CDG57_03585	COG0833	amino acid
CDG57_03595	COG2233	PERMEase
CDG57_03605	COG1970	mechanosensitive ion channel activity
CDG57_03615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_03635	COG0354	folic acid binding
CDG57_03645	COG3189	MarR family transcriptional regulator
CDG57_03650	COG2824	Alkylphosphonate utilization operon protein PhnA
CDG57_03655	COG3422	double-strand break repair
CDG57_03685	COG0840	transmembrane signaling receptor activity
CDG57_03690	COG0643	Histidine kinase
CDG57_03690	COG2198	Histidine kinase
CDG57_03690	COG2198	Histidine kinase
CDG57_03690	COG0643	Histidine kinase
CDG57_03705	COG5510	response to toxic substance
CDG57_03715	COG2832	Protein of unknown function (DUF454)
CDG57_03720	COG1376	ErfK ybiS ycfS ynhG family protein
CDG57_03765	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDG57_03775	COG1289	transmembrane transporter activity
CDG57_03795	COG0786	glutamate:sodium symporter activity
CDG57_03800	COG1115	amino acid carrier protein
CDG57_03805	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG57_03810	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CDG57_03855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG57_03865	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDG57_03870	COG1077	Cell shape determining protein MreB Mrl
CDG57_03875	COG1792	Involved in formation and maintenance of cell shape
CDG57_03885	COG0424	maF-like protein
CDG57_03890	COG1530	ribonuclease E activity
CDG57_03900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDG57_03920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG57_03945	COG2851	Citrate transporter
CDG57_03955	COG0671	phosphoesterase, PA-phosphatase related
CDG57_03960	COG0174	glutamine synthetase
CDG57_03975	COG1113	amino acid transport
CDG57_03985	COG0142	geranyltranstransferase activity
CDG57_03990	COG2814	Major facilitator Superfamily
CDG57_04005	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDG57_04025	COG2194	sulfuric ester hydrolase activity
CDG57_04030	COG0745	RESPONSE REGULATOR receiver
CDG57_04035	COG0642	Histidine kinase
CDG57_04050	COG0004	ammonium transporteR
CDG57_04065	COG0525	valine-tRNA ligase activity
CDG57_04075	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_04080	COG0393	Putative heavy-metal-binding
CDG57_04085	COG0393	Putative heavy-metal-binding
CDG57_04090	COG1538	Outer membrane efflux protein
CDG57_04100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_04105	COG0671	phosphoesterase, PA-phosphatase related
CDG57_04135	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_04140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDG57_04155	COG1648	precorrin-2 dehydrogenase activity
CDG57_04155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDG57_04160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDG57_04165	COG1733	regulation of RNA biosynthetic process
CDG57_04175	COG0531	amino acid
CDG57_04190	COG0321	lipoyl(octanoyl) transferase activity
CDG57_04225	COG0500	methyltransferase
CDG57_04230	COG0586	Pfam SNARE associated Golgi protein
CDG57_04260	COG2009	succinate dehydrogenase
CDG57_04265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CDG57_04270	COG1053	succinate dehydrogenase
CDG57_04275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDG57_04290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_04305	COG2268	Band 7 protein
CDG57_04310	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDG57_04320	COG2354	Protein conserved in bacteria
CDG57_04325	COG2321	neutral zinc metallopeptidase
CDG57_04340	COG0589	response to stress
CDG57_04360	COG0505	Belongs to the CarA family
CDG57_04385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_04390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDG57_04395	COG2304	oxidoreductase activity
CDG57_04415	COG3201	nicotinamide mononucleotide transporter
CDG57_04420	COG0584	glycerophosphoryl diester phosphodiesterase
CDG57_04425	COG2194	sulfuric ester hydrolase activity
CDG57_04440	COG2239	Acts as a magnesium transporter
CDG57_04450	COG0501	Belongs to the peptidase M48B family
CDG57_04455	COG0741	lytic transglycosylase activity
CDG57_04470	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CDG57_04505	COG0071	Belongs to the small heat shock protein (HSP20) family
CDG57_04510	COG0542	response to heat
CDG57_04555	COG0501	Belongs to the peptidase M48B family
CDG57_04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_04565	COG3293	Transposase
CDG57_04590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG57_04610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDG57_04740	COG1301	dicarboxylic acid transport
CDG57_04750	COG0583	DNA-binding transcription factor activity
CDG57_04765	COG1607	acyl-coa hydrolase
CDG57_04775	COG0523	cobalamin synthesis protein
CDG57_04780	COG4681	YaeQ
CDG57_04795	COG0726	polysaccharide deacetylase
CDG57_04795	COG1649	PFAM Uncharacterised BCR, COG1649
CDG57_04800	COG1215	transferase activity, transferring glycosyl groups
CDG57_04820	COG3293	Transposase
CDG57_04860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDG57_04875	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CDG57_04915	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CDG57_04935	COG4771	TonB-dependent receptor
CDG57_04950	COG0288	reversible hydration of carbon dioxide
CDG57_04965	COG4181	ATPase activity
CDG57_04970	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CDG57_04975	COG0457	Tetratricopeptide repeat
CDG57_04975	COG0705	Rhomboid family
CDG57_04990	COG2070	2-Nitropropane dioxygenase
CDG57_04995	COG1294	oxidase, subunit
CDG57_05000	COG1271	oxidase subunit
CDG57_05015	COG0415	Belongs to the DNA photolyase family
CDG57_05025	COG1252	NADH dehydrogenase
CDG57_05030	COG1686	Belongs to the peptidase S11 family
CDG57_05050	COG1187	pseudouridine synthase activity
CDG57_05065	COG0612	Peptidase, M16
CDG57_05095	COG0352	thiamine-phosphate diphosphorylase activity
CDG57_05105	COG0564	pseudouridine synthase activity
CDG57_05115	COG0783	Belongs to the Dps family
CDG57_05125	COG1309	transcriptional regulator
CDG57_05145	COG1309	transcriptional regulator
CDG57_05155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDG57_05160	COG0076	glutamate decarboxylase activity
CDG57_05175	COG0573	inorganic phosphate transmembrane transporter activity
CDG57_05185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDG57_05190	COG0616	signal peptide processing
CDG57_05215	COG0742	ribosomal rna small subunit methyltransferase
CDG57_05220	COG0768	penicillin binding
CDG57_05245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDG57_05250	COG2878	Part of a membrane complex involved in electron transport
CDG57_05255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_05265	COG3384	dioxygenase
CDG57_05280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDG57_05305	COG3831	ATPase activity
CDG57_05310	COG0714	Associated with various cellular activities
CDG57_05320	COG3552	Protein containing von Willebrand factor type A (VWA) domain
CDG57_05355	COG0006	proline dipeptidase activity
CDG57_05360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_05365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_05420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG57_05425	COG0741	lytic transglycosylase activity
CDG57_05425	COG1388	LysM domain
CDG57_05430	COG4166	transmembrane transport
CDG57_05435	COG4174	ABC transporter (Permease)
CDG57_05440	COG4239	(ABC) transporter, permease
CDG57_05445	COG4172	Belongs to the ABC transporter superfamily
CDG57_05465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDG57_05475	COG5001	Diguanylate cyclase
CDG57_05475	COG4251	negative regulation of phosphorylation
CDG57_05475	COG2203	Gaf domain
CDG57_05475	COG3706	GGDEF domain
CDG57_05490	COG3739	integral membrane protein
CDG57_05525	COG3293	Transposase
CDG57_05540	COG3217	Mosc domain protein beta barrel domain protein
CDG57_05540	COG0633	Ferredoxin
CDG57_05550	COG0512	Glutamine amidotransferase of anthranilate synthase
CDG57_05560	COG3161	chorismate lyase activity
CDG57_05565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDG57_05600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG57_05605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG57_05610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_05620	COG2223	nitrite transmembrane transporter activity
CDG57_05630	COG0024	Methionine aminopeptidase
CDG57_05635	COG0052	Belongs to the universal ribosomal protein uS2 family
CDG57_05650	COG0281	malic enzyme
CDG57_05650	COG0280	phosphate acetyltransferase
CDG57_05660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDG57_05665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDG57_05670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDG57_05695	COG2011	ABC-type metal ion transport system permease component
CDG57_05700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG57_05710	COG0151	Belongs to the GarS family
CDG57_05715	COG0138	bifunctional purine biosynthesis protein purh
CDG57_05720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CDG57_05785	COG2252	PERMEase
CDG57_05790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDG57_05795	COG3038	cytochrome b561
CDG57_05810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDG57_05820	COG0527	aspartate kinase activity
CDG57_05830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDG57_05845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDG57_05855	COG2308	Evidence 4 Homologs of previously reported genes of
CDG57_05865	COG1305	Transglutaminase-like
CDG57_05875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDG57_05880	COG0305	Participates in initiation and elongation during chromosome replication
CDG57_05915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDG57_05920	COG1845	cytochrome c oxidase, subunit III
CDG57_05925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDG57_05930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDG57_05955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG57_05980	COG0564	pseudouridine synthase activity
CDG57_05990	COG0802	atpase or kinase
CDG57_05995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDG57_06005	COG1923	regulation of RNA biosynthetic process
CDG57_06010	COG0697	spore germination
CDG57_06015	COG0778	Nitroreductase
CDG57_06020	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_06030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG57_06040	COG0519	Catalyzes the synthesis of GMP from XMP
CDG57_06040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG57_06050	COG0531	amino acid
CDG57_06060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG57_06115	COG0308	aminopeptidase N
CDG57_06130	COG1714	RDD family
CDG57_06135	COG0475	glutathione-regulated potassium exporter activity
CDG57_06135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG57_06140	COG3135	benzoate transporter
CDG57_06165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDG57_06195	COG0316	Belongs to the HesB IscA family
CDG57_06200	COG0822	iron-sulfur transferase activity
CDG57_06230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_06245	COG2137	regulation of response to DNA damage stimulus
CDG57_06255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDG57_06260	COG1011	Hydrolase
CDG57_06280	COG0268	Binds directly to 16S ribosomal RNA
CDG57_06285	COG0702	epimerase
CDG57_06290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CDG57_06340	COG0424	maF-like protein
CDG57_06365	COG0778	Nitroreductase
CDG57_06400	COG1286	toxin biosynthetic process
CDG57_06450	COG3634	alkyl hydroperoxide reductase activity
CDG57_06455	COG2267	carboxylic ester hydrolase activity
CDG57_06490	COG0436	Aminotransferase
CDG57_06500	COG0386	Belongs to the glutathione peroxidase family
CDG57_06550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG57_06565	COG0012	GTP binding
CDG57_06570	COG2011	ABC-type metal ion transport system permease component
CDG57_06575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDG57_06580	COG1464	Belongs to the NlpA lipoprotein family
CDG57_06615	COG0204	Acyl-transferase
CDG57_06640	COG1560	Kdo2-lipid A biosynthetic process
CDG57_06705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_06755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG57_06775	COG4682	membrane
CDG57_06790	COG2808	Putative FMN-binding domain
CDG57_06805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDG57_06815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_06840	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDG57_06870	COG0729	surface antigen
CDG57_06900	COG0471	metal ion transport
CDG57_06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDG57_06920	COG3647	Membrane
CDG57_06925	COG2814	Major facilitator Superfamily
CDG57_06930	COG0583	DNA-binding transcription factor activity
CDG57_06940	COG3293	Transposase
CDG57_06965	COG1720	tRNA m6t6A37 methyltransferase activity
CDG57_06975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDG57_06985	COG0745	RESPONSE REGULATOR receiver
CDG57_06990	COG0642	Histidine kinase
CDG57_07000	COG0494	nUDIX hydrolase
CDG57_07010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDG57_07020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDG57_07025	COG3139	Protein of unknown function (DUF1315)
CDG57_07060	COG1960	acyl-CoA dehydrogenase activity
CDG57_07075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDG57_07090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CDG57_07095	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDG57_07115	COG1690	Belongs to the RtcB family
CDG57_07120	COG1234	tRNA 3'-trailer cleavage
CDG57_07130	COG4650	regulator
CDG57_07195	COG0513	Belongs to the DEAD box helicase family
CDG57_07205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDG57_07215	COG3178	'Phosphotransferase
CDG57_07220	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDG57_07230	COG1192	Involved in chromosome partitioning
CDG57_07235	COG1475	DNA binding
CDG57_07240	COG0811	peptide transport
CDG57_07250	COG1132	(ABC) transporter
CDG57_07255	COG1663	tetraacyldisaccharide 4'-kinase activity
CDG57_07275	COG0084	hydrolase, TatD family'
CDG57_07320	COG0590	tRNA wobble adenosine to inosine editing
CDG57_07340	COG0776	regulation of translation
CDG57_07375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CDG57_07380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CDG57_07415	COG0024	Methionine aminopeptidase
CDG57_07420	COG0583	DNA-binding transcription factor activity
CDG57_07425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_07435	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG57_07440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG57_07445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG57_07445	COG0517	IMP dehydrogenase activity
CDG57_07470	COG0552	protein localization to endoplasmic reticulum
CDG57_07500	COG4890	Cyd operon protein YbgT
CDG57_07505	COG1294	oxidase, subunit
CDG57_07530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDG57_07550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDG57_07555	COG0569	domain protein
CDG57_07560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDG57_07565	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDG57_07590	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG57_07595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDG57_07600	COG0542	response to heat
CDG57_07610	COG0488	(ABC) transporter
CDG57_07620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG57_07625	COG2267	carboxylic ester hydrolase activity
CDG57_07635	COG1902	pentaerythritol trinitrate reductase activity
CDG57_07635	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG57_07675	COG0148	phosphopyruvate hydratase activity
CDG57_07680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDG57_07725	COG1802	Transcriptional regulator
CDG57_07740	COG1063	alcohol dehydrogenase
CDG57_07770	COG1454	alcohol dehydrogenase
CDG57_07780	COG2814	Major facilitator Superfamily
CDG57_07785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_07790	COG0183	Belongs to the thiolase family
CDG57_07795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDG57_07800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDG57_07805	COG3135	benzoate transporter
CDG57_07810	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_07815	COG0543	2 iron, 2 sulfur cluster binding
CDG57_07815	COG0633	Ferredoxin
CDG57_07820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CDG57_07825	COG4638	Rieske (2fe-2S)
CDG57_07835	COG4829	muconolactone delta-isomerase
CDG57_07840	COG4948	Mandelate Racemase Muconate Lactonizing
CDG57_07845	COG0583	DNA-binding transcription factor activity
CDG57_07855	COG1944	ATP diphosphatase activity
CDG57_07870	COG0583	DNA-binding transcription factor activity
CDG57_07885	COG1024	Enoyl-CoA hydratase
CDG57_07890	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDG57_07895	COG1960	acyl-CoA dehydrogenase activity
CDG57_07900	COG1309	transcriptional regulator
CDG57_07905	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_07945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDG57_07950	COG0730	response to heat
CDG57_08285	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDG57_08295	COG3706	GGDEF domain
CDG57_08310	COG0133	tryptophan synthase activity
CDG57_08320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDG57_08340	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDG57_08370	COG0537	adenosine 5'-monophosphoramidase activity
CDG57_08395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_08415	COG0730	response to heat
CDG57_08420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDG57_08450	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDG57_08465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDG57_08480	COG2223	nitrite transmembrane transporter activity
CDG57_08510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDG57_08525	COG1960	acyl-CoA dehydrogenase activity
CDG57_08530	COG1960	acyl-CoA dehydrogenase activity
CDG57_08535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_08540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_08545	COG2207	Transcriptional regulator
CDG57_08550	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_08560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDG57_08585	COG0575	Belongs to the CDS family
CDG57_08590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDG57_08595	COG0233	cytoplasmic translational termination
CDG57_08610	COG3852	Histidine kinase
CDG57_08615	COG2204	response regulator
CDG57_08690	COG0303	'Molybdopterin
CDG57_08695	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDG57_08695	COG0315	cyclic pyranopterin monophosphate synthase activity
CDG57_08710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDG57_08715	COG0243	molybdopterin cofactor binding
CDG57_08720	COG3048	D-serine ammonia-lyase activity
CDG57_08730	COG0243	molybdopterin cofactor binding
CDG57_08735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_08740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_08740	COG2146	nitrite reductase [NAD(P)H] activity
CDG57_08745	COG2223	nitrite transmembrane transporter activity
CDG57_08755	COG1116	anion transmembrane transporter activity
CDG57_08755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_08785	COG2814	Major facilitator Superfamily
CDG57_08790	COG1113	amino acid transport
CDG57_08800	COG0625	glutathione transferase activity
CDG57_08820	COG0069	glutamate synthase activity
CDG57_08855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDG57_08860	COG1454	alcohol dehydrogenase
CDG57_08865	COG0824	Thioesterase
CDG57_08870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDG57_08875	COG2850	peptidyl-arginine hydroxylation
CDG57_08890	COG0640	Transcriptional regulator
CDG57_08910	COG3122	Protein conserved in bacteria
CDG57_08915	COG0668	transmembrane transport
CDG57_08930	COG1132	(ABC) transporter
CDG57_08950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG57_08960	COG0506	proline dehydrogenase activity
CDG57_08960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG57_08960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CDG57_08965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDG57_08975	COG3698	Phosphodiester glycosidase
CDG57_08990	COG3811	Belongs to the UPF0386 family
CDG57_09000	COG2353	YceI-like domain
CDG57_09010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDG57_09015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDG57_09055	COG1278	Cold shock
CDG57_09075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDG57_09075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDG57_09100	COG3539	Fimbrial protein
CDG57_09120	COG1309	transcriptional regulator
CDG57_09135	COG1979	alcohol dehydrogenase
CDG57_09145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CDG57_09160	COG0604	alcohol dehydrogenase
CDG57_09160	COG3321	synthase
CDG57_09165	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CDG57_09170	COG0583	DNA-binding transcription factor activity
CDG57_09175	COG4221	oxidoreductase activity
CDG57_09205	COG0277	FAD linked oxidase domain protein
CDG57_09215	COG2186	Transcriptional regulator
CDG57_09225	COG3177	Filamentation induced by cAMP protein fic
CDG57_09265	COG1131	(ABC) transporter
CDG57_09270	COG0842	Transport permease protein
CDG57_09285	COG0772	Belongs to the SEDS family
CDG57_09290	COG2951	lytic endotransglycosylase activity
CDG57_09310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDG57_09315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDG57_09335	COG1643	Atp-dependent helicase
CDG57_09355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_09375	COG3634	alkyl hydroperoxide reductase activity
CDG57_09395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDG57_09445	COG1765	OsmC-like protein
CDG57_09455	COG0501	Belongs to the peptidase M48B family
CDG57_09460	COG4770	biotin carboxylase activity
CDG57_09465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDG57_09470	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDG57_09475	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDG57_09480	COG2072	flavoprotein involved in K transport
CDG57_09500	COG1309	transcriptional regulator
CDG57_09535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_09540	COG0010	Belongs to the arginase family
CDG57_09570	COG2188	Transcriptional regulator
CDG57_09600	COG1116	anion transmembrane transporter activity
CDG57_09605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_09625	COG2186	Transcriptional regulator
CDG57_09635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDG57_09645	COG3293	Transposase
CDG57_09655	COG2351	hydroxyisourate hydrolase activity
CDG57_09680	COG0745	RESPONSE REGULATOR receiver
CDG57_09685	COG0642	Histidine kinase
CDG57_09690	COG4106	trans-aconitate 2-methyltransferase activity
CDG57_09700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CDG57_09740	COG1960	acyl-CoA dehydrogenase activity
CDG57_09765	COG3293	Transposase
CDG57_09785	COG3293	Transposase
CDG57_09800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDG57_09825	COG2132	Multicopper oxidase
CDG57_09840	COG2205	protein histidine kinase activity
CDG57_09845	COG2217	Heavy metal translocating P-type atpase
CDG57_09885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDG57_09895	COG2184	nucleotidyltransferase activity
CDG57_09960	COG0789	Transcriptional regulator
CDG57_10015	COG1902	pentaerythritol trinitrate reductase activity
CDG57_10015	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDG57_10025	COG1741	Belongs to the pirin family
CDG57_10095	COG0714	Associated with various cellular activities
CDG57_10100	COG2879	small protein
CDG57_10105	COG1966	Carbon starvation protein
CDG57_10110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDG57_10115	COG1509	lysine 2,3-aminomutase activity
CDG57_10155	COG1067	ATP-dependent peptidase activity
CDG57_10160	COG0583	DNA-binding transcription factor activity
CDG57_10185	COG1686	Belongs to the peptidase S11 family
CDG57_10190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDG57_10205	COG0482	sulfurtransferase activity
CDG57_10250	COG0028	Belongs to the TPP enzyme family
CDG57_10265	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_10285	COG1414	Transcriptional regulator
CDG57_10310	COG2815	serine threonine protein kinase
CDG57_10310	COG0515	serine threonine protein kinase
CDG57_10330	COG0697	spore germination
CDG57_10345	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDG57_10350	COG1610	YqeY-like protein
CDG57_10365	COG4783	chaperone-mediated protein folding
CDG57_10370	COG0204	Acyl-transferase
CDG57_10400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG57_10405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDG57_10420	COG2351	hydroxyisourate hydrolase activity
CDG57_10435	COG5002	protein histidine kinase activity
CDG57_10455	COG0772	Belongs to the SEDS family
CDG57_10460	COG1253	flavin adenine dinucleotide binding
CDG57_10470	COG3842	ATPase activity
CDG57_10475	COG1840	ABC-type Fe3 transport system, periplasmic component
CDG57_10490	COG3293	Transposase
CDG57_10500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CDG57_10550	COG1137	ATPase activity
CDG57_10555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CDG57_10565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CDG57_10570	COG0517	IMP dehydrogenase activity
CDG57_10570	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDG57_10605	COG1253	flavin adenine dinucleotide binding
CDG57_10610	COG0222	ribosome binding
CDG57_10625	COG0175	sulfate reduction
CDG57_10635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDG57_10645	COG1773	rubredoxin
CDG57_10650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDG57_10655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_10660	COG0583	DNA-binding transcription factor activity
CDG57_10720	COG0556	nucleotide-excision repair
CDG57_10765	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDG57_10780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDG57_10785	COG0571	ribonuclease III activity
CDG57_10800	COG0481	GTPase activity
CDG57_10810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDG57_10825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDG57_10830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDG57_10835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDG57_10845	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDG57_10850	COG4208	sulfate ABC transporter
CDG57_10855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDG57_10860	COG0583	DNA-binding transcription factor activity
CDG57_10875	COG0602	queuosine metabolic process
CDG57_10880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDG57_10895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG57_10915	COG1942	4-Oxalocrotonate Tautomerase
CDG57_10920	COG0625	glutathione transferase activity
CDG57_10930	COG1056	cytidyltransferase-related domain
CDG57_10930	COG1051	belongs to the nudix hydrolase family
CDG57_10935	COG1024	Enoyl-CoA hydratase
CDG57_10940	COG0778	Nitroreductase
CDG57_10945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDG57_10945	COG3323	Protein of unknown function (DUF1653)
CDG57_10955	COG2814	Major facilitator Superfamily
CDG57_10960	COG0047	phosphoribosylformylglycinamidine synthase activity
CDG57_10960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDG57_10985	COG0824	Thioesterase
CDG57_11005	COG0823	Involved in the tonB-independent uptake of proteins
CDG57_11025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG57_11060	COG2826	transposase and inactivated derivatives, IS30 family
CDG57_11080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDG57_11085	COG0628	permease
CDG57_11095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDG57_11105	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CDG57_11105	COG0616	signal peptide processing
CDG57_11115	COG0658	competence protein
CDG57_11115	COG2333	competence protein COMEC
CDG57_11120	COG1136	(ABC) transporter
CDG57_11125	COG4591	ABC-type transport system involved in lipoprotein release permease component
CDG57_11140	COG1671	Belongs to the UPF0178 family
CDG57_11160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_11180	COG2318	DinB family
CDG57_11200	COG1280	lysine exporter protein (LysE YggA)
CDG57_11210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDG57_11215	COG0019	diaminopimelate decarboxylase activity
CDG57_11225	COG1113	amino acid transport
CDG57_11230	COG1115	amino acid carrier protein
CDG57_11250	COG0306	phosphate transporter
CDG57_11260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_11270	COG0242	peptide deformylase activity
CDG57_11290	COG0589	response to stress
CDG57_11295	COG2175	clavaminate synthase activity
CDG57_11300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG57_11315	COG4521	taurine ABC transporter
CDG57_11325	COG1230	cation diffusion facilitator family transporter
CDG57_11340	COG4149	molybdate abc transporter
CDG57_11345	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDG57_11370	COG3040	lipid binding
CDG57_11375	COG0833	amino acid
CDG57_11390	COG1012	belongs to the aldehyde dehydrogenase family
CDG57_11400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDG57_11405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDG57_11440	COG0582	viral genome integration into host DNA
CDG57_11480	COG0629	single-stranded DNA binding
CDG57_11485	COG2217	Heavy metal translocating P-type atpase
CDG57_11490	COG0789	Transcriptional regulator
CDG57_11500	COG2814	Major facilitator Superfamily
CDG57_11505	COG1566	PFAM secretion protein HlyD family protein
CDG57_11510	COG2050	protein possibly involved in aromatic compounds catabolism
CDG57_11520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDG57_11525	COG1090	epimerase
CDG57_11575	COG0420	3'-5' exonuclease activity
CDG57_11605	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDG57_11625	COG0121	glutamine amidotransferase
CDG57_11640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG57_11645	COG0756	dUTP diphosphatase activity
CDG57_11650	COG0210	DNA helicase
CDG57_11655	COG2885	chlorophyll binding
CDG57_11660	COG0204	Acyl-transferase
CDG57_11670	COG0850	regulation of cytokinetic process
CDG57_11680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDG57_11690	COG1280	lysine exporter protein (LysE YggA)
CDG57_11695	COG1674	ftsk spoiiie
CDG57_11700	COG0492	ferredoxin-NADP+ reductase activity
CDG57_11705	COG0500	methyltransferase
CDG57_11710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDG57_11720	COG0456	acetyltransferase
CDG57_11735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG57_11745	COG0049	tRNA binding
CDG57_11780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG57_11780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDG57_11805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDG57_11850	COG0564	pseudouridine synthase activity
CDG57_11875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CDG57_11905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDG57_11930	COG3293	Transposase
CDG57_11950	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDG57_11960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDG57_11960	COG0352	thiamine-phosphate diphosphorylase activity
CDG57_11960	COG0351	phosphomethylpyrimidine kinase
CDG57_11965	COG1652	LysM domain
CDG57_11985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDG57_11990	COG1399	metal-binding, possibly nucleic acid-binding protein
CDG57_11995	COG3101	peptidyl-lysine hydroxylation
CDG57_12000	COG0009	L-threonylcarbamoyladenylate synthase
CDG57_12015	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDG57_12020	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDG57_12030	COG4172	Belongs to the ABC transporter superfamily
CDG57_12055	COG4166	transmembrane transport
CDG57_12100	COG4106	trans-aconitate 2-methyltransferase activity
CDG57_12115	COG2226	methyltransferase
CDG57_12115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CDG57_12115	COG0596	Alpha beta hydrolase
CDG57_12125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDG57_12145	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDG57_12155	COG1196	nuclear chromosome segregation
CDG57_12165	COG0730	response to heat
CDG57_12185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDG57_12195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG57_12200	COG4636	protein conserved in cyanobacteria
CDG57_12250	COG0489	protein tyrosine kinase activity
CDG57_12275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG57_12275	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDG57_12285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG57_12320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CDG57_12330	COG2081	HI0933 family
CDG57_12340	COG0668	transmembrane transport
CDG57_12355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDG57_12360	COG0583	DNA-binding transcription factor activity
CDG57_12365	COG1278	Cold shock
CDG57_12390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_12395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG57_12400	COG0713	ATP synthesis coupled electron transport
CDG57_12410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_12425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CDG57_12435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_12435	COG0649	NAD binding
CDG57_12445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDG57_12450	COG3706	GGDEF domain
CDG57_12460	COG2205	protein histidine kinase activity
CDG57_12465	COG0745	RESPONSE REGULATOR receiver
CDG57_12485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDG57_12490	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CDG57_12605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDG57_12610	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDG57_12640	COG2132	Multicopper oxidase
CDG57_12650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDG57_12675	COG1968	undecaprenyl-diphosphatase activity
CDG57_12715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDG57_12720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDG57_12725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDG57_12785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDG57_12795	COG1764	response to oxidative stress
CDG57_12820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG57_12820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDG57_12835	COG0037	tRNA processing
CDG57_12845	COG0248	Ppx GppA phosphatase
CDG57_12870	COG0072	phenylalanine-tRNA ligase activity
CDG57_12890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDG57_12905	COG1238	metal cluster binding
CDG57_12915	COG0625	glutathione transferase activity
CDG57_12940	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_12945	COG3028	Belongs to the UPF0307 family
CDG57_12970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDG57_12975	COG0617	tRNA 3'-terminal CCA addition
CDG57_12980	COG1555	photosystem II stabilization
CDG57_12985	COG3956	TIGRFAM MazG family protein
CDG57_12995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDG57_13015	COG5002	protein histidine kinase activity
CDG57_13015	COG2205	protein histidine kinase activity
CDG57_13015	COG0784	Response regulator, receiver
CDG57_13020	COG1024	Enoyl-CoA hydratase
CDG57_13025	COG2084	Dehydrogenase
CDG57_13030	COG3622	Belongs to the hyi family
CDG57_13045	COG0004	ammonium transporteR
CDG57_13050	COG0300	oxidoreductase activity
CDG57_13055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CDG57_13060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG57_13065	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDG57_13080	COG2814	Major facilitator Superfamily
CDG57_13105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDG57_13110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG57_13120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDG57_13125	COG3706	GGDEF domain
CDG57_13160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDG57_13170	COG0732	type I restriction modification DNA specificity domain
CDG57_13180	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDG57_13200	COG0174	glutamine synthetase
CDG57_13215	COG0745	RESPONSE REGULATOR receiver
CDG57_13220	COG2205	protein histidine kinase activity
CDG57_13230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CDG57_13235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CDG57_13315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDG57_13325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDG57_13340	COG0084	hydrolase, TatD family'
CDG57_13345	COG0726	polysaccharide deacetylase
CDG57_13355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDG57_13370	COG0431	NADPH-dependent FMN reductase
CDG57_13375	COG0798	PFAM Bile acid sodium symporter
CDG57_13385	COG0640	Transcriptional regulator
CDG57_13395	COG3243	poly(R)-hydroxyalkanoic acid synthase
CDG57_13410	COG0440	acetolactate synthase activity
CDG57_13415	COG0028	Belongs to the TPP enzyme family
CDG57_13435	COG1466	dna polymerase III delta subunit
CDG57_13440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDG57_13445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_13450	COG0577	efflux transmembrane transporter activity
CDG57_13450	COG1136	(ABC) transporter
CDG57_13455	COG1538	Outer membrane efflux protein
CDG57_13480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CDG57_13485	COG1162	GTPase activity
CDG57_13520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDG57_13525	COG2003	Belongs to the UPF0758 family
CDG57_13530	COG3781	membrane
CDG57_13535	COG0613	PHP domain protein
CDG57_13545	COG2350	Protein conserved in bacteria
CDG57_13565	COG1666	GTP binding
CDG57_13580	COG1956	GAF domain-containing protein
CDG57_13585	COG1607	acyl-coa hydrolase
CDG57_13600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG57_13600	COG3453	Protein conserved in bacteria
CDG57_13640	COG1183	phosphatidylcholine synthase activity
CDG57_13645	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CDG57_13675	COG0739	heme binding
CDG57_13675	COG0741	lytic transglycosylase activity
CDG57_13675	COG1196	nuclear chromosome segregation
CDG57_13685	COG1702	phosphate starvation-inducible protein PhoH
CDG57_13700	COG4773	Receptor
CDG57_13770	COG0788	formyltetrahydrofolate deformylase activity
CDG57_13785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDG57_13790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDG57_13795	COG4651	solute:proton antiporter activity
CDG57_13795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDG57_13820	COG0724	RNA recognition motif
CDG57_13825	COG0210	DNA helicase
CDG57_13875	COG1560	Kdo2-lipid A biosynthetic process
CDG57_13930	COG0473	3-isopropylmalate dehydrogenase activity
CDG57_13955	COG0583	DNA-binding transcription factor activity
CDG57_13980	COG0494	nUDIX hydrolase
CDG57_13990	COG0753	catalase activity
CDG57_14000	COG0583	DNA-binding transcription factor activity
CDG57_14035	COG1530	ribonuclease E activity
CDG57_14060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDG57_14070	COG0534	Mate efflux family protein
CDG57_14075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG57_14130	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CDG57_14135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDG57_14150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDG57_14160	COG0644	oxidoreductase
CDG57_14160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CDG57_14170	COG1595	DNA-templated transcription, initiation
CDG57_14185	COG3220	belongs to the UPF0276 family
CDG57_14200	COG1279	arginine transmembrane transporter activity
CDG57_14205	COG0425	Belongs to the sulfur carrier protein TusA family
CDG57_14210	COG4535	Mg2 and Co2 transporter CorC
CDG57_14235	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDG57_14245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDG57_14260	COG0789	Transcriptional regulator
CDG57_14265	COG0598	Magnesium transport protein CorA
CDG57_14270	COG1185	polyribonucleotide nucleotidyltransferase activity
CDG57_14275	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDG57_14285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDG57_14290	COG1074	ATP-dependent DNA helicase activity
CDG57_14295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CDG57_14320	COG2226	methyltransferase
CDG57_14330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDG57_14345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDG57_14360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDG57_14360	COG2111	Na H antiporter
CDG57_14365	COG1006	Multisubunit Na H antiporter MnhC subunit
CDG57_14370	COG0651	ATP synthesis coupled electron transport
CDG57_14380	COG2212	antiporter activity
CDG57_14390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDG57_14400	COG0195	Participates in both transcription termination and antitermination
CDG57_14450	COG0237	dephospho-CoA kinase activity
CDG57_14460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDG57_14470	COG0497	DNA recombination
CDG57_14480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDG57_14505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDG57_14535	COG3706	GGDEF domain
CDG57_14565	COG1132	(ABC) transporter
CDG57_14575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDG57_14595	COG0326	Molecular chaperone. Has ATPase activity
CDG57_14610	COG2056	Na+-H+ antiporter family
CDG57_14650	COG0081	regulation of translation
CDG57_14655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDG57_14675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDG57_14705	COG0546	phosphoglycolate phosphatase activity
CDG57_14710	COG1716	ATPase activity
CDG57_14755	COG0181	hydroxymethylbilane synthase activity
CDG57_14765	COG3275	phosphorelay sensor kinase activity
CDG57_14805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDG57_14810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDG57_14815	COG0772	Belongs to the SEDS family
CDG57_14840	COG4974	Belongs to the 'phage' integrase family
CDG57_14845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG57_14855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDG57_14875	COG2197	response regulator
CDG57_14890	COG0793	Belongs to the peptidase S41A family
CDG57_14895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDG57_14900	COG0795	lipopolysaccharide-transporting ATPase activity
CDG57_14905	COG0795	lipopolysaccharide-transporting ATPase activity
CDG57_14940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG57_14940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDG57_14950	COG0004	ammonium transporteR
CDG57_14955	COG0347	Belongs to the P(II) protein family
CDG57_14965	COG0606	chelatase, subunit chli
CDG57_14990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDG57_15005	COG0318	PFAM AMP-dependent synthetase and ligase
CDG57_15025	COG2860	membrane
CDG57_15035	COG1253	flavin adenine dinucleotide binding
CDG57_15055	COG2814	Major facilitator Superfamily
CDG57_15070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDG57_15075	COG0745	RESPONSE REGULATOR receiver
CDG57_15080	COG2205	protein histidine kinase activity
CDG57_15085	COG4452	Inner membrane protein CreD
CDG57_15110	COG2814	Major facilitator Superfamily
CDG57_15130	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDG57_15150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDG57_15185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDG57_15205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDG57_15210	COG3162	membrane
CDG57_15215	COG2205	protein histidine kinase activity
CDG57_15215	COG0784	Response regulator, receiver
CDG57_15240	COG1652	LysM domain
CDG57_15245	COG0758	DNA mediated transformation
CDG57_15260	COG1309	transcriptional regulator
CDG57_15275	COG0386	Belongs to the glutathione peroxidase family
CDG57_15295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDG57_15300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDG57_15305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDG57_15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDG57_15345	COG1121	(ABC) transporter
CDG57_15350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDG57_15360	COG2837	iron assimilation
CDG57_15370	COG0281	malic enzyme
CDG57_15400	COG3706	GGDEF domain
CDG57_15400	COG0745	RESPONSE REGULATOR receiver
CDG57_15405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDG57_15405	COG0519	Catalyzes the synthesis of GMP from XMP
CDG57_15410	COG4399	Belongs to the UPF0754 family
CDG57_15420	COG2259	Doxx family
CDG57_15425	COG0586	Pfam SNARE associated Golgi protein
CDG57_15440	COG1192	Involved in chromosome partitioning
CDG57_15450	COG0271	Belongs to the BolA IbaG family
CDG57_15485	COG3756	Protein conserved in bacteria
CDG57_15515	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDG57_15520	COG0842	Transport permease protein
CDG57_15525	COG0842	Transport permease protein
CDG57_15525	COG1129	ABC transporter
CDG57_15530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDG57_15580	COG3550	peptidyl-serine autophosphorylation
CDG57_15585	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDG57_15665	COG0477	Major facilitator Superfamily
CDG57_15670	COG1024	Enoyl-CoA hydratase
CDG57_15675	COG1024	Enoyl-CoA hydratase
CDG57_15680	COG1960	acyl-CoA dehydrogenase activity
CDG57_15685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDG57_15705	COG1113	amino acid transport
CDG57_15710	COG0251	oxidation-reduction process
CDG57_15725	COG1522	sequence-specific DNA binding
CDG57_15745	COG0564	pseudouridine synthase activity
CDG57_15790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDG57_15805	COG1802	Transcriptional regulator
CDG57_15810	COG1448	Aminotransferase
CDG57_15815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDG57_15820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDG57_15835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDG57_15840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG57_15875	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDG57_15880	COG1088	dTDP-glucose 4,6-dehydratase activity
CDG57_15905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDG57_15915	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDG57_15950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDG57_15955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDG57_15965	COG0545	Peptidyl-prolyl cis-trans isomerase
CDG57_15970	COG0728	peptidoglycan biosynthetic process
CDG57_15975	COG3023	N-Acetylmuramoyl-L-alanine amidase
CDG57_15990	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDG57_16025	COG0546	phosphoglycolate phosphatase activity
CDG57_16030	COG1028	Short-chain dehydrogenase reductase Sdr
CDG57_16040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDG57_16040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDG57_16045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDG57_16055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDG57_16060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDG57_16065	COG1116	anion transmembrane transporter activity
CDG57_16070	COG1309	transcriptional regulator
CDG57_16085	COG0196	riboflavin kinase activity
CDG57_16090	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDG57_16100	COG1047	Peptidyl-prolyl cis-trans
CDG57_16140	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDG57_16160	COG0583	DNA-binding transcription factor activity
CDG57_16170	COG0443	Heat shock 70 kDa protein
CDG57_16175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDG57_16200	COG2951	lytic endotransglycosylase activity
CDG57_16205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDG57_16225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDG57_16245	COG1960	acyl-CoA dehydrogenase activity
CDG57_16250	COG0583	DNA-binding transcription factor activity
CDG57_16260	COG0861	Integral membrane protein TerC family
CDG57_16270	COG0754	glutathionylspermidine amidase activity
CDG57_16280	COG0402	S-adenosylhomocysteine deaminase activity
CDG57_16295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDG57_16310	COG0706	membrane insertase activity
CDG57_16325	COG0230	Belongs to the bacterial ribosomal protein bL34 family