locus-tag	class	description
OTEC02_00010	COG0592	DNA-directed DNA polymerase activity
OTEC02_00020	COG0187	DNA topoisomerase II activity
OTEC02_00035	COG0488	(ABC) transporter
OTEC02_00065	COG0596	Alpha beta hydrolase
OTEC02_00070	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OTEC02_00075	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OTEC02_00105	COG0625	glutathione transferase activity
OTEC02_00115	COG0733	neurotransmitter:sodium symporter activity
OTEC02_00155	COG2233	PERMEase
OTEC02_00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_00205	COG2814	Major facilitator Superfamily
OTEC02_00210	COG0656	L-ascorbic acid biosynthetic process
OTEC02_00215	COG0583	DNA-binding transcription factor activity
OTEC02_00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_00235	COG1064	alcohol dehydrogenase
OTEC02_00240	COG2818	Glycosylase
OTEC02_00255	COG1194	a g-specific adenine glycosylase
OTEC02_00270	COG5487	UPF0391 membrane protein
OTEC02_00275	COG2983	Belongs to the UPF0260 family
OTEC02_00280	COG2133	pyrroloquinoline quinone binding
OTEC02_00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OTEC02_00290	COG2116	formate transmembrane transporter activity
OTEC02_00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_00315	COG1335	isochorismatase
OTEC02_00320	COG0385	Bile acid
OTEC02_00325	COG0534	Mate efflux family protein
OTEC02_00330	COG1683	Conserved Protein
OTEC02_00345	COG0346	lactoylglutathione lyase activity
OTEC02_00350	COG0625	glutathione transferase activity
OTEC02_00360	COG1113	amino acid transport
OTEC02_00370	COG0523	cobalamin synthesis protein
OTEC02_00380	COG2188	Transcriptional regulator
OTEC02_00410	COG0010	Belongs to the arginase family
OTEC02_00420	COG0546	phosphoglycolate phosphatase activity
OTEC02_00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OTEC02_00445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OTEC02_00455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OTEC02_00460	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OTEC02_00565	COG0534	Mate efflux family protein
OTEC02_00570	COG0436	Aminotransferase
OTEC02_00575	COG2733	membrane
OTEC02_00590	COG2918	glutathione biosynthetic process
OTEC02_00600	COG3501	Rhs element vgr protein
OTEC02_00605	COG0791	NLP P60 protein
OTEC02_00605	COG1388	LysM domain
OTEC02_00620	COG3150	esterase
OTEC02_00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OTEC02_00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_00650	COG2233	PERMEase
OTEC02_00655	COG2351	hydroxyisourate hydrolase activity
OTEC02_00690	COG3706	GGDEF domain
OTEC02_00705	COG1393	Belongs to the ArsC family
OTEC02_00710	COG0708	Exodeoxyribonuclease III
OTEC02_00735	COG0189	ligase activity
OTEC02_00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OTEC02_00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OTEC02_00780	COG4942	peptidase
OTEC02_00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_00800	COG2119	membrane
OTEC02_00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_00810	COG0426	domain, Protein
OTEC02_00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OTEC02_00855	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_00860	COG1519	Transferase
OTEC02_00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OTEC02_00870	COG0668	transmembrane transport
OTEC02_00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OTEC02_00885	COG1335	isochorismatase
OTEC02_00890	COG1522	sequence-specific DNA binding
OTEC02_00915	COG0784	Response regulator, receiver
OTEC02_00915	COG2198	Histidine kinase
OTEC02_00915	COG2205	protein histidine kinase activity
OTEC02_00920	COG3162	membrane
OTEC02_00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OTEC02_00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_00945	COG3706	GGDEF domain
OTEC02_00960	COG1309	transcriptional regulator
OTEC02_00980	COG0300	oxidoreductase activity
OTEC02_00990	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_00990	COG0351	phosphomethylpyrimidine kinase
OTEC02_00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OTEC02_01000	COG2814	Major facilitator Superfamily
OTEC02_01015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OTEC02_01025	COG1113	amino acid transport
OTEC02_01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OTEC02_01040	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_01050	COG1335	isochorismatase
OTEC02_01090	COG0583	DNA-binding transcription factor activity
OTEC02_01100	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_01110	COG2814	Major facilitator Superfamily
OTEC02_01115	COG0583	DNA-binding transcription factor activity
OTEC02_01135	COG0667	Aldo Keto reductase
OTEC02_01170	COG1733	regulation of RNA biosynthetic process
OTEC02_01175	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_01240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OTEC02_01260	COG0697	spore germination
OTEC02_01285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OTEC02_01315	COG0427	acetyl-CoA hydrolase
OTEC02_01325	COG2205	protein histidine kinase activity
OTEC02_01330	COG0745	RESPONSE REGULATOR receiver
OTEC02_01340	COG0659	secondary active sulfate transmembrane transporter activity
OTEC02_01345	COG4221	oxidoreductase activity
OTEC02_01355	COG0488	(ABC) transporter
OTEC02_01435	COG0833	amino acid
OTEC02_01480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OTEC02_01485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OTEC02_01500	COG2226	methyltransferase
OTEC02_01555	COG0069	glutamate synthase activity
OTEC02_01555	COG0070	glutamate synthase
OTEC02_01555	COG0067	glutamate synthase
OTEC02_01560	COG0493	'glutamate synthase
OTEC02_01570	COG1704	LemA family
OTEC02_01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OTEC02_01585	COG4969	Belongs to the N-Me-Phe pilin family
OTEC02_01595	COG3307	-O-antigen
OTEC02_01615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OTEC02_01625	COG0194	GDP metabolic process
OTEC02_01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OTEC02_01685	COG0335	large ribosomal subunit rRNA binding
OTEC02_01695	COG5380	lipid catabolic process
OTEC02_01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OTEC02_01720	COG5006	permease, DMT superfamily
OTEC02_01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OTEC02_01730	COG0277	FAD linked oxidase domain protein
OTEC02_01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OTEC02_01745	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_01760	COG1289	transmembrane transporter activity
OTEC02_01770	COG0628	permease
OTEC02_01775	COG1192	Involved in chromosome partitioning
OTEC02_01805	COG0833	amino acid
OTEC02_01810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OTEC02_01815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OTEC02_01825	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_01850	COG1404	Belongs to the peptidase S8 family
OTEC02_01865	COG0583	DNA-binding transcription factor activity
OTEC02_01870	COG1794	racemase activity, acting on amino acids and derivatives
OTEC02_01875	COG0583	DNA-binding transcription factor activity
OTEC02_01890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OTEC02_01905	COG0752	glycyl-tRNA synthetase alpha subunit
OTEC02_01930	COG4109	DRTGG domain
OTEC02_01935	COG1983	PspC domain protein
OTEC02_01945	COG1960	acyl-CoA dehydrogenase activity
OTEC02_01960	COG0408	coproporphyrinogen oxidase activity
OTEC02_01980	COG0513	Belongs to the DEAD box helicase family
OTEC02_01990	COG1127	ABC transporter
OTEC02_01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OTEC02_02005	COG2854	intermembrane phospholipid transfer
OTEC02_02015	COG0598	Magnesium transport protein CorA
OTEC02_02025	COG0494	nUDIX hydrolase
OTEC02_02030	COG1040	competence protein
OTEC02_02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OTEC02_02055	COG1946	Acyl-CoA thioesterase
OTEC02_02060	COG1301	dicarboxylic acid transport
OTEC02_02075	COG1959	2 iron, 2 sulfur cluster binding
OTEC02_02080	COG1017	nitric oxide dioxygenase activity
OTEC02_02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_02085	COG0433	COG0433 Predicted ATPase
OTEC02_02090	COG0626	cystathionine gamma-synthase activity
OTEC02_02105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OTEC02_02110	COG0088	Forms part of the polypeptide exit tunnel
OTEC02_02210	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OTEC02_02220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OTEC02_02245	COG1960	acyl-CoA dehydrogenase activity
OTEC02_02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OTEC02_02280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OTEC02_02285	COG0339	signal peptide processing
OTEC02_02290	COG0557	exoribonuclease II activity
OTEC02_02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
OTEC02_02340	COG1295	ribonuclease BN
OTEC02_02375	COG1702	phosphate starvation-inducible protein PhoH
OTEC02_02385	COG0741	lytic transglycosylase activity
OTEC02_02385	COG1196	nuclear chromosome segregation
OTEC02_02385	COG0739	heme binding
OTEC02_02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OTEC02_02420	COG1183	phosphatidylcholine synthase activity
OTEC02_02465	COG1960	acyl-CoA dehydrogenase activity
OTEC02_02470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OTEC02_02475	COG1309	transcriptional regulator
OTEC02_02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OTEC02_02495	COG1960	acyl-CoA dehydrogenase activity
OTEC02_02515	COG2969	positive regulation of protein catabolic process
OTEC02_02525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OTEC02_02530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OTEC02_02535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OTEC02_02540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OTEC02_02545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OTEC02_02565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OTEC02_02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OTEC02_02580	COG1408	metallophosphoesterase
OTEC02_02585	COG2885	chlorophyll binding
OTEC02_02585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OTEC02_02590	COG2199	diguanylate cyclase activity
OTEC02_02645	COG3453	Protein conserved in bacteria
OTEC02_02645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OTEC02_02660	COG1607	acyl-coa hydrolase
OTEC02_02695	COG2350	Protein conserved in bacteria
OTEC02_02710	COG3781	membrane
OTEC02_02720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OTEC02_02735	COG1862	Preprotein translocase
OTEC02_02755	COG0582	viral genome integration into host DNA
OTEC02_02860	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OTEC02_02900	COG0726	polysaccharide deacetylase
OTEC02_02905	COG0463	Glycosyl transferase, family 2
OTEC02_02910	COG0438	transferase activity, transferring glycosyl groups
OTEC02_02925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OTEC02_02925	COG1215	transferase activity, transferring glycosyl groups
OTEC02_02975	COG3223	Belongs to the PsiE family
OTEC02_02980	COG0625	glutathione transferase activity
OTEC02_02985	COG0583	DNA-binding transcription factor activity
OTEC02_02990	COG1960	acyl-CoA dehydrogenase activity
OTEC02_02995	COG1960	acyl-CoA dehydrogenase activity
OTEC02_03005	COG2205	protein histidine kinase activity
OTEC02_03010	COG0745	RESPONSE REGULATOR receiver
OTEC02_03020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OTEC02_03040	COG2096	Adenosyltransferase
OTEC02_03045	COG4206	TonB-dependent receptor
OTEC02_03055	COG0133	tryptophan synthase activity
OTEC02_03090	COG0285	dihydrofolate synthase activity
OTEC02_03115	COG0450	alkyl hydroperoxide reductase
OTEC02_03130	COG0477	Major facilitator Superfamily
OTEC02_03135	COG1272	protein, Hemolysin III
OTEC02_03145	COG2153	protein acetylation
OTEC02_03165	COG0183	Belongs to the thiolase family
OTEC02_03170	COG2207	Transcriptional regulator
OTEC02_03190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_03210	COG0183	Belongs to the thiolase family
OTEC02_03220	COG2885	chlorophyll binding
OTEC02_03220	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OTEC02_03225	COG1690	Belongs to the RtcB family
OTEC02_03230	COG0833	amino acid
OTEC02_03240	COG2233	PERMEase
OTEC02_03270	COG2094	Belongs to the DNA glycosylase MPG family
OTEC02_03275	COG4772	TonB-dependent receptor
OTEC02_03280	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_03285	COG0679	Auxin Efflux Carrier
OTEC02_03295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_03300	COG0354	folic acid binding
OTEC02_03315	COG3189	MarR family transcriptional regulator
OTEC02_03320	COG2824	Alkylphosphonate utilization operon protein PhnA
OTEC02_03325	COG3422	double-strand break repair
OTEC02_03365	COG0840	transmembrane signaling receptor activity
OTEC02_03380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OTEC02_03395	COG5510	response to toxic substance
OTEC02_03405	COG2832	Protein of unknown function (DUF454)
OTEC02_03410	COG1376	ErfK ybiS ycfS ynhG family protein
OTEC02_03460	COG1289	transmembrane transporter activity
OTEC02_03465	COG2814	Major facilitator Superfamily
OTEC02_03490	COG1115	amino acid carrier protein
OTEC02_03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
OTEC02_03500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OTEC02_03505	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OTEC02_03530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OTEC02_03540	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OTEC02_03545	COG1077	Cell shape determining protein MreB Mrl
OTEC02_03550	COG1792	Involved in formation and maintenance of cell shape
OTEC02_03555	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OTEC02_03560	COG0424	maF-like protein
OTEC02_03565	COG1530	ribonuclease E activity
OTEC02_03575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_03595	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_03620	COG2207	Transcriptional regulator
OTEC02_03645	COG1113	amino acid transport
OTEC02_03655	COG0142	geranyltranstransferase activity
OTEC02_03660	COG2315	Protein conserved in bacteria
OTEC02_03675	COG1752	Esterase of the alpha-beta hydrolase superfamily
OTEC02_03700	COG2194	sulfuric ester hydrolase activity
OTEC02_03705	COG0745	RESPONSE REGULATOR receiver
OTEC02_03710	COG0642	Histidine kinase
OTEC02_03720	COG0004	ammonium transporteR
OTEC02_03725	COG0583	DNA-binding transcription factor activity
OTEC02_03745	COG0525	valine-tRNA ligase activity
OTEC02_03755	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_03765	COG0393	Putative heavy-metal-binding
OTEC02_03770	COG0393	Putative heavy-metal-binding
OTEC02_03775	COG1538	Outer membrane efflux protein
OTEC02_03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_03790	COG0671	phosphoesterase, PA-phosphatase related
OTEC02_03815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OTEC02_03830	COG1648	precorrin-2 dehydrogenase activity
OTEC02_03830	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OTEC02_03835	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OTEC02_03870	COG0531	amino acid
OTEC02_03885	COG0321	lipoyl(octanoyl) transferase activity
OTEC02_03895	COG2921	Belongs to the UPF0250 family
OTEC02_03935	COG2009	succinate dehydrogenase
OTEC02_03940	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OTEC02_03945	COG1053	succinate dehydrogenase
OTEC02_03950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OTEC02_03975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_04010	COG2354	Protein conserved in bacteria
OTEC02_04015	COG2321	neutral zinc metallopeptidase
OTEC02_04035	COG2843	Capsule synthesis protein
OTEC02_04050	COG0589	response to stress
OTEC02_04070	COG0505	Belongs to the CarA family
OTEC02_04105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OTEC02_04110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OTEC02_04160	COG0477	Major facilitator Superfamily
OTEC02_04165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OTEC02_04185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OTEC02_04215	COG0584	glycerophosphoryl diester phosphodiesterase
OTEC02_04235	COG0741	lytic transglycosylase activity
OTEC02_04255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OTEC02_04260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OTEC02_04295	COG1309	transcriptional regulator
OTEC02_04300	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_04305	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_04305	COG0596	Alpha beta hydrolase
OTEC02_04310	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_04310	COG0596	Alpha beta hydrolase
OTEC02_04315	COG0596	Alpha beta hydrolase
OTEC02_04320	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_04325	COG0583	DNA-binding transcription factor activity
OTEC02_04330	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
OTEC02_04335	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_04350	COG0778	Nitroreductase
OTEC02_04355	COG1929	Belongs to the glycerate kinase type-1 family
OTEC02_04360	COG0243	molybdopterin cofactor binding
OTEC02_04365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OTEC02_04370	COG3339	Conserved Protein
OTEC02_04395	COG1115	amino acid carrier protein
OTEC02_04400	COG1113	amino acid transport
OTEC02_04410	COG0019	diaminopimelate decarboxylase activity
OTEC02_04420	COG1280	lysine exporter protein (LysE YggA)
OTEC02_04425	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OTEC02_04455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_04480	COG0697	spore germination
OTEC02_04485	COG4591	ABC-type transport system involved in lipoprotein release permease component
OTEC02_04490	COG1136	(ABC) transporter
OTEC02_04495	COG0658	competence protein
OTEC02_04495	COG2333	competence protein COMEC
OTEC02_04505	COG0616	signal peptide processing
OTEC02_04505	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OTEC02_04510	COG0596	Alpha beta hydrolase
OTEC02_04515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OTEC02_04525	COG0628	permease
OTEC02_04565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OTEC02_04585	COG0823	Involved in the tonB-independent uptake of proteins
OTEC02_04605	COG0824	Thioesterase
OTEC02_04610	COG1473	amidohydrolase
OTEC02_04630	COG0047	phosphoribosylformylglycinamidine synthase activity
OTEC02_04630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OTEC02_04635	COG2814	Major facilitator Superfamily
OTEC02_04640	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OTEC02_04645	COG1024	Enoyl-CoA hydratase
OTEC02_04650	COG1051	belongs to the nudix hydrolase family
OTEC02_04650	COG1056	cytidyltransferase-related domain
OTEC02_04665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OTEC02_04680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OTEC02_04685	COG0602	queuosine metabolic process
OTEC02_04695	COG4625	pathogenesis
OTEC02_04700	COG0583	DNA-binding transcription factor activity
OTEC02_04705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OTEC02_04710	COG4208	sulfate ABC transporter
OTEC02_04715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OTEC02_04725	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OTEC02_04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OTEC02_04735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OTEC02_04755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OTEC02_04765	COG0481	GTPase activity
OTEC02_04770	COG0681	Belongs to the peptidase S26 family
OTEC02_04780	COG0571	ribonuclease III activity
OTEC02_04785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OTEC02_04795	COG1381	Involved in DNA repair and RecF pathway recombination
OTEC02_04800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OTEC02_04810	COG4221	oxidoreductase activity
OTEC02_04860	COG0556	nucleotide-excision repair
OTEC02_04870	COG2962	Rard protein
OTEC02_04915	COG2070	2-Nitropropane dioxygenase
OTEC02_04930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OTEC02_04945	COG1215	transferase activity, transferring glycosyl groups
OTEC02_04960	COG0415	Belongs to the DNA photolyase family
OTEC02_04970	COG1252	NADH dehydrogenase
OTEC02_04975	COG1686	Belongs to the peptidase S11 family
OTEC02_04990	COG1187	pseudouridine synthase activity
OTEC02_05005	COG0477	Major facilitator Superfamily
OTEC02_05010	COG0583	DNA-binding transcription factor activity
OTEC02_05025	COG0612	Peptidase, M16
OTEC02_05050	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_05085	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_05110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OTEC02_05115	COG0076	glutamate decarboxylase activity
OTEC02_05125	COG1522	sequence-specific DNA binding
OTEC02_05130	COG3961	Belongs to the TPP enzyme family
OTEC02_05135	COG1113	amino acid transport
OTEC02_05140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OTEC02_05145	COG0573	inorganic phosphate transmembrane transporter activity
OTEC02_05155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OTEC02_05160	COG0616	signal peptide processing
OTEC02_05195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OTEC02_05200	COG1686	Belongs to the peptidase S11 family
OTEC02_05220	COG1388	LysM domain
OTEC02_05220	COG4942	peptidase
OTEC02_05225	COG0583	DNA-binding transcription factor activity
OTEC02_05230	COG1067	ATP-dependent peptidase activity
OTEC02_05270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OTEC02_05275	COG1966	Carbon starvation protein
OTEC02_05280	COG2879	small protein
OTEC02_05295	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OTEC02_05315	COG1741	Belongs to the pirin family
OTEC02_05330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_05340	COG4605	iron ion homeostasis
OTEC02_05345	COG4604	ABC transporter, ATP-binding protein
OTEC02_05350	COG4607	ABC-type enterochelin transport system periplasmic component
OTEC02_05355	COG4774	siderophore transport
OTEC02_05365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OTEC02_05370	COG1021	2,3-dihydroxybenzoate-AMP ligase
OTEC02_05375	COG3433	isochorismatase activity
OTEC02_05375	COG1535	isochorismatase
OTEC02_05390	COG1132	(ABC) transporter
OTEC02_05395	COG1132	(ABC) transporter
OTEC02_05400	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OTEC02_05410	COG1169	isochorismate synthase
OTEC02_05430	COG3739	integral membrane protein
OTEC02_05450	COG0302	gtp cyclohydrolase
OTEC02_05460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OTEC02_05470	COG2840	Smr protein MutS2
OTEC02_05485	COG0512	Glutamine amidotransferase of anthranilate synthase
OTEC02_05500	COG3104	oligopeptide transport
OTEC02_05515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OTEC02_05550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OTEC02_05555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OTEC02_05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OTEC02_05580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OTEC02_05585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OTEC02_05590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OTEC02_05605	COG1960	acyl-CoA dehydrogenase activity
OTEC02_05610	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OTEC02_05615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_05625	COG2223	nitrite transmembrane transporter activity
OTEC02_05635	COG0024	Methionine aminopeptidase
OTEC02_05640	COG0052	Belongs to the universal ribosomal protein uS2 family
OTEC02_05655	COG2207	Transcriptional regulator
OTEC02_05680	COG2951	lytic endotransglycosylase activity
OTEC02_05685	COG0772	Belongs to the SEDS family
OTEC02_05700	COG0842	Transport permease protein
OTEC02_05705	COG1131	(ABC) transporter
OTEC02_05740	COG1538	Outer membrane efflux protein
OTEC02_05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_05760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_05765	COG4215	(ABC) transporter
OTEC02_05770	COG4160	amino acid transport
OTEC02_05775	COG4598	ABC transporter
OTEC02_05785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OTEC02_05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_05810	COG1720	tRNA m6t6A37 methyltransferase activity
OTEC02_05830	COG0745	RESPONSE REGULATOR receiver
OTEC02_05835	COG0642	Histidine kinase
OTEC02_05845	COG0494	nUDIX hydrolase
OTEC02_05855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OTEC02_05860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OTEC02_05865	COG3139	Protein of unknown function (DUF1315)
OTEC02_05870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OTEC02_05880	COG1301	dicarboxylic acid transport
OTEC02_05885	COG1960	acyl-CoA dehydrogenase activity
OTEC02_05905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OTEC02_05915	COG2195	Cleaves the N-terminal amino acid of tripeptides
OTEC02_05920	COG1234	tRNA 3'-trailer cleavage
OTEC02_05945	COG2363	Small membrane protein
OTEC02_05965	COG0513	Belongs to the DEAD box helicase family
OTEC02_05975	COG0778	Nitroreductase
OTEC02_06005	COG1286	toxin biosynthetic process
OTEC02_06030	COG4783	chaperone-mediated protein folding
OTEC02_06035	COG1610	YqeY-like protein
OTEC02_06040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OTEC02_06090	COG1278	Cold shock
OTEC02_06110	COG2207	Transcriptional regulator
OTEC02_06115	COG3243	poly(R)-hydroxyalkanoic acid synthase
OTEC02_06120	COG1335	isochorismatase
OTEC02_06125	COG0583	DNA-binding transcription factor activity
OTEC02_06130	COG0786	glutamate:sodium symporter activity
OTEC02_06135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OTEC02_06135	COG0475	glutathione-regulated potassium exporter activity
OTEC02_06150	COG1309	transcriptional regulator
OTEC02_06160	COG2985	domain, Protein
OTEC02_06170	COG2995	paraquat-inducible protein a
OTEC02_06175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OTEC02_06175	COG3008	intermembrane lipid transfer
OTEC02_06185	COG2351	hydroxyisourate hydrolase activity
OTEC02_06225	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OTEC02_06235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OTEC02_06240	COG0642	Histidine kinase
OTEC02_06245	COG0745	RESPONSE REGULATOR receiver
OTEC02_06265	COG1794	racemase activity, acting on amino acids and derivatives
OTEC02_06275	COG2175	clavaminate synthase activity
OTEC02_06280	COG3246	L-lysine catabolic process to acetate
OTEC02_06285	COG2814	Major facilitator Superfamily
OTEC02_06300	COG2855	membrane
OTEC02_06335	COG2814	Major facilitator Superfamily
OTEC02_06360	COG1301	dicarboxylic acid transport
OTEC02_06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OTEC02_06375	COG2011	ABC-type metal ion transport system permease component
OTEC02_06380	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OTEC02_06390	COG0151	Belongs to the GarS family
OTEC02_06400	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OTEC02_06430	COG0735	belongs to the Fur family
OTEC02_06455	COG2308	Evidence 4 Homologs of previously reported genes of
OTEC02_06465	COG1305	Transglutaminase-like
OTEC02_06475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OTEC02_06480	COG0305	Participates in initiation and elongation during chromosome replication
OTEC02_06505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OTEC02_06515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OTEC02_06545	COG1649	PFAM Uncharacterised BCR, COG1649
OTEC02_06545	COG0726	polysaccharide deacetylase
OTEC02_06550	COG1215	transferase activity, transferring glycosyl groups
OTEC02_06555	COG3658	cytochrome
OTEC02_06565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_06580	COG0583	DNA-binding transcription factor activity
OTEC02_06595	COG2890	protein-(glutamine-N5) methyltransferase activity
OTEC02_06600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_06605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_06620	COG1960	acyl-CoA dehydrogenase activity
OTEC02_06625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_06640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OTEC02_06650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OTEC02_06655	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OTEC02_06665	COG2205	protein histidine kinase activity
OTEC02_06675	COG0174	glutamine synthetase
OTEC02_06695	COG0729	surface antigen
OTEC02_06745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OTEC02_06750	COG2814	Major facilitator Superfamily
OTEC02_06760	COG0583	DNA-binding transcription factor activity
OTEC02_06775	COG1187	pseudouridine synthase activity
OTEC02_06795	COG0802	atpase or kinase
OTEC02_06810	COG1923	regulation of RNA biosynthetic process
OTEC02_06815	COG0697	spore germination
OTEC02_06825	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_06840	COG0519	Catalyzes the synthesis of GMP from XMP
OTEC02_06840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OTEC02_06845	COG4302	ethanolamine ammonia-lyase activity
OTEC02_06850	COG4303	Ethanolamine ammonia lyase large subunit
OTEC02_06855	COG0531	amino acid
OTEC02_06880	COG1454	alcohol dehydrogenase
OTEC02_06885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OTEC02_06895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OTEC02_06915	COG0308	aminopeptidase N
OTEC02_06955	COG1605	Chorismate mutase
OTEC02_06980	COG4772	TonB-dependent receptor
OTEC02_06985	COG4774	siderophore transport
OTEC02_07030	COG3772	lysozyme
OTEC02_07040	COG1733	regulation of RNA biosynthetic process
OTEC02_07065	COG0583	DNA-binding transcription factor activity
OTEC02_07105	COG0488	(ABC) transporter
OTEC02_07110	COG0589	response to stress
OTEC02_07130	COG3135	benzoate transporter
OTEC02_07135	COG1522	sequence-specific DNA binding
OTEC02_07145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OTEC02_07150	COG0583	DNA-binding transcription factor activity
OTEC02_07160	COG0183	Belongs to the thiolase family
OTEC02_07200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OTEC02_07210	COG0824	Thioesterase
OTEC02_07215	COG1454	alcohol dehydrogenase
OTEC02_07240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OTEC02_07270	COG0069	glutamate synthase activity
OTEC02_07295	COG2814	Major facilitator Superfamily
OTEC02_07305	COG0439	Biotin carboxylase
OTEC02_07310	COG0511	ligase activity, forming carbon-carbon bonds
OTEC02_07330	COG4264	IucA IucC family
OTEC02_07345	COG4264	IucA IucC family
OTEC02_07350	COG4264	IucA IucC family
OTEC02_07360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OTEC02_07380	COG1116	anion transmembrane transporter activity
OTEC02_07380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_07395	COG2146	nitrite reductase [NAD(P)H] activity
OTEC02_07395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_07400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_07405	COG0243	molybdopterin cofactor binding
OTEC02_07415	COG0243	molybdopterin cofactor binding
OTEC02_07420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OTEC02_07435	COG0521	Mo-molybdopterin cofactor biosynthetic process
OTEC02_07435	COG0315	cyclic pyranopterin monophosphate synthase activity
OTEC02_07440	COG0303	'Molybdopterin
OTEC02_07450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_07455	COG0697	spore germination
OTEC02_07480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_07545	COG2204	response regulator
OTEC02_07550	COG3852	Histidine kinase
OTEC02_07575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OTEC02_07595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_07615	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_07630	COG2137	regulation of response to DNA damage stimulus
OTEC02_07640	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OTEC02_07645	COG1011	Hydrolase
OTEC02_07660	COG1522	sequence-specific DNA binding
OTEC02_07670	COG1113	amino acid transport
OTEC02_07690	COG0659	secondary active sulfate transmembrane transporter activity
OTEC02_07710	COG3300	MHYT domain
OTEC02_07710	COG5001	Diguanylate cyclase
OTEC02_07725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OTEC02_07725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OTEC02_07725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OTEC02_07730	COG1105	Belongs to the carbohydrate kinase PfkB family
OTEC02_07735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OTEC02_07735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OTEC02_07755	COG3193	protein, possibly involved in utilization of glycolate and propanediol
OTEC02_07765	COG0024	Methionine aminopeptidase
OTEC02_07770	COG0583	DNA-binding transcription factor activity
OTEC02_07780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OTEC02_07785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OTEC02_07790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OTEC02_07790	COG0517	IMP dehydrogenase activity
OTEC02_07815	COG0552	protein localization to endoplasmic reticulum
OTEC02_07825	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OTEC02_07840	COG4890	Cyd operon protein YbgT
OTEC02_07845	COG1294	oxidase, subunit
OTEC02_07860	COG1585	Membrane protein implicated in regulation of membrane protease activity
OTEC02_07870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OTEC02_07885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OTEC02_07890	COG0569	domain protein
OTEC02_07895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OTEC02_07925	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OTEC02_07930	COG0542	response to heat
OTEC02_07940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OTEC02_07955	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_07955	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_07995	COG0148	phosphopyruvate hydratase activity
OTEC02_08000	COG2323	membrane
OTEC02_08010	COG4773	Receptor
OTEC02_08015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OTEC02_08025	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_08030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_08035	COG0183	Belongs to the thiolase family
OTEC02_08040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OTEC02_08045	COG0596	Alpha beta hydrolase
OTEC02_08050	COG2271	Major facilitator Superfamily
OTEC02_08055	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OTEC02_08060	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_08065	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_08070	COG0710	3-dehydroquinate dehydratase activity
OTEC02_08075	COG3420	alginic acid biosynthetic process
OTEC02_08080	COG3659	wide pore channel activity
OTEC02_08085	COG4993	Dehydrogenase
OTEC02_08095	COG2391	methyltransferase activity
OTEC02_08110	COG1414	Transcriptional regulator
OTEC02_08115	COG0583	DNA-binding transcription factor activity
OTEC02_08120	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08145	COG2814	Major facilitator Superfamily
OTEC02_08155	COG0154	amidase activity
OTEC02_08175	COG4638	Rieske (2fe-2S)
OTEC02_08185	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_08205	COG3733	amine oxidase
OTEC02_08220	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_08230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_08235	COG0183	Belongs to the thiolase family
OTEC02_08240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_08245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_08255	COG4829	muconolactone delta-isomerase
OTEC02_08260	COG4948	Mandelate Racemase Muconate Lactonizing
OTEC02_08265	COG0583	DNA-binding transcription factor activity
OTEC02_08275	COG2186	Transcriptional regulator
OTEC02_08295	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_08300	COG1309	transcriptional regulator
OTEC02_08305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OTEC02_08330	COG1538	Outer membrane efflux protein
OTEC02_08335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_08340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_08345	COG0745	RESPONSE REGULATOR receiver
OTEC02_08350	COG2205	protein histidine kinase activity
OTEC02_08380	COG2072	flavoprotein involved in K transport
OTEC02_08385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OTEC02_08420	COG1946	Acyl-CoA thioesterase
OTEC02_08425	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_08430	COG0583	DNA-binding transcription factor activity
OTEC02_08450	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08455	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08460	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08470	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08475	COG0183	Belongs to the thiolase family
OTEC02_08485	COG2271	Major facilitator Superfamily
OTEC02_08490	COG0251	oxidation-reduction process
OTEC02_08500	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08520	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08525	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08530	COG3829	transcription factor binding
OTEC02_08550	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08555	COG1414	Transcriptional regulator
OTEC02_08575	COG3659	wide pore channel activity
OTEC02_08580	COG1309	transcriptional regulator
OTEC02_08600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OTEC02_08610	COG1053	succinate dehydrogenase
OTEC02_08615	COG1053	succinate dehydrogenase
OTEC02_08625	COG1846	Transcriptional regulator
OTEC02_08630	COG1024	Enoyl-CoA hydratase
OTEC02_08635	COG2814	Major facilitator Superfamily
OTEC02_08655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OTEC02_08655	COG0644	oxidoreductase
OTEC02_08665	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08670	COG1960	acyl-CoA dehydrogenase activity
OTEC02_08680	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OTEC02_08690	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_08705	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OTEC02_08715	COG0583	DNA-binding transcription factor activity
OTEC02_08735	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_08740	COG1454	alcohol dehydrogenase
OTEC02_08745	COG3485	protocatechuate 3,4-dioxygenase
OTEC02_08760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_08765	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_08770	COG0183	Belongs to the thiolase family
OTEC02_08795	COG1234	tRNA 3'-trailer cleavage
OTEC02_08800	COG2271	Major facilitator Superfamily
OTEC02_08810	COG3971	2-oxopent-4-enoate hydratase activity
OTEC02_08815	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OTEC02_08835	COG0583	DNA-binding transcription factor activity
OTEC02_08840	COG4638	Rieske (2fe-2S)
OTEC02_08845	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OTEC02_08855	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08860	COG3384	dioxygenase
OTEC02_08865	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_08870	COG2814	Major facilitator Superfamily
OTEC02_08875	COG2814	Major facilitator Superfamily
OTEC02_08880	COG0583	DNA-binding transcription factor activity
OTEC02_08900	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_08900	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_08945	COG1309	transcriptional regulator
OTEC02_08955	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_08970	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_08975	COG1733	regulation of RNA biosynthetic process
OTEC02_08980	COG0583	DNA-binding transcription factor activity
OTEC02_09095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_09110	COG2271	Major facilitator Superfamily
OTEC02_09115	COG1566	PFAM secretion protein HlyD family protein
OTEC02_09130	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_09140	COG0129	dihydroxy-acid dehydratase activity
OTEC02_09150	COG0583	DNA-binding transcription factor activity
OTEC02_09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OTEC02_09165	COG2084	Dehydrogenase
OTEC02_09170	COG2207	Transcriptional regulator
OTEC02_09175	COG1064	alcohol dehydrogenase
OTEC02_09185	COG1309	transcriptional regulator
OTEC02_09205	COG1120	ATPase activity
OTEC02_09215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OTEC02_09280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OTEC02_09315	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
OTEC02_09330	COG1073	alpha beta
OTEC02_09345	COG3539	Fimbrial protein
OTEC02_09370	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OTEC02_09380	COG0753	catalase activity
OTEC02_09400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OTEC02_09465	COG3433	isochorismatase activity
OTEC02_09465	COG1535	isochorismatase
OTEC02_09470	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_09490	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OTEC02_09495	COG4149	molybdate abc transporter
OTEC02_09500	COG0725	ABC transporter, periplasmic molybdate-binding protein
OTEC02_09505	COG2005	Transcriptional regulator
OTEC02_09510	COG4638	Rieske (2fe-2S)
OTEC02_09515	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OTEC02_09520	COG0543	2 iron, 2 sulfur cluster binding
OTEC02_09520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_09535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_09545	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_09550	COG0412	Dienelactone hydrolase
OTEC02_09565	COG2207	Transcriptional regulator
OTEC02_09570	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_09575	COG2610	gluconate transmembrane transporter activity
OTEC02_09595	COG0583	DNA-binding transcription factor activity
OTEC02_09610	COG2031	fatty acid transporter
OTEC02_09615	COG0183	Belongs to the thiolase family
OTEC02_09620	COG0583	DNA-binding transcription factor activity
OTEC02_09625	COG0583	DNA-binding transcription factor activity
OTEC02_09640	COG1027	Aspartate ammonia-lyase
OTEC02_09650	COG0477	Major facilitator Superfamily
OTEC02_09670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_09675	COG4521	taurine ABC transporter
OTEC02_09700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OTEC02_09705	COG1733	regulation of RNA biosynthetic process
OTEC02_09710	COG2207	Transcriptional regulator
OTEC02_09710	COG3708	Transcriptional regulator
OTEC02_09725	COG0730	response to heat
OTEC02_09745	COG3781	membrane
OTEC02_09750	COG1063	alcohol dehydrogenase
OTEC02_09760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OTEC02_09765	COG0508	dehydrogenase complex catalyzes the overall conversion of
OTEC02_09770	COG0022	dehydrogenase e1 component
OTEC02_09775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OTEC02_09780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OTEC02_09795	COG3706	GGDEF domain
OTEC02_09815	COG0133	tryptophan synthase activity
OTEC02_09825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OTEC02_09855	COG0583	DNA-binding transcription factor activity
OTEC02_09860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OTEC02_09870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OTEC02_09925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OTEC02_09930	COG4773	Receptor
OTEC02_09950	COG0730	response to heat
OTEC02_09955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OTEC02_09975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OTEC02_09995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OTEC02_10010	COG1960	acyl-CoA dehydrogenase activity
OTEC02_10015	COG1960	acyl-CoA dehydrogenase activity
OTEC02_10020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_10025	COG2207	Transcriptional regulator
OTEC02_10030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OTEC02_10035	COG0776	regulation of translation
OTEC02_10060	COG0822	iron-sulfur transferase activity
OTEC02_10065	COG0316	Belongs to the HesB IscA family
OTEC02_10095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OTEC02_10115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OTEC02_10120	COG0702	epimerase
OTEC02_10160	COG0601	transmembrane transport
OTEC02_10165	COG0339	signal peptide processing
OTEC02_10170	COG4166	transmembrane transport
OTEC02_10210	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OTEC02_10215	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OTEC02_10230	COG2431	L-lysine efflux transmembrane transporter activity
OTEC02_10245	COG0776	regulation of translation
OTEC02_10265	COG0590	tRNA wobble adenosine to inosine editing
OTEC02_10310	COG0084	hydrolase, TatD family'
OTEC02_10330	COG1663	tetraacyldisaccharide 4'-kinase activity
OTEC02_10335	COG1132	(ABC) transporter
OTEC02_10345	COG0811	peptide transport
OTEC02_10350	COG1475	DNA binding
OTEC02_10355	COG1192	Involved in chromosome partitioning
OTEC02_10365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OTEC02_10370	COG3178	'Phosphotransferase
OTEC02_10380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OTEC02_10405	COG0424	maF-like protein
OTEC02_10410	COG2850	peptidyl-arginine hydroxylation
OTEC02_10420	COG0640	Transcriptional regulator
OTEC02_10430	COG3619	membrane
OTEC02_10435	COG3122	Protein conserved in bacteria
OTEC02_10440	COG1132	(ABC) transporter
OTEC02_10460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OTEC02_10465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OTEC02_10475	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OTEC02_10475	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OTEC02_10475	COG0506	proline dehydrogenase activity
OTEC02_10480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OTEC02_10495	COG3698	Phosphodiester glycosidase
OTEC02_10505	COG2353	YceI-like domain
OTEC02_10515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OTEC02_10560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OTEC02_10560	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OTEC02_10585	COG3539	Fimbrial protein
OTEC02_10590	COG3121	Chaperone
OTEC02_10610	COG0583	DNA-binding transcription factor activity
OTEC02_10615	COG0697	spore germination
OTEC02_10625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OTEC02_10650	COG1309	transcriptional regulator
OTEC02_10665	COG1522	sequence-specific DNA binding
OTEC02_10675	COG1126	abc transporter atp-binding protein
OTEC02_10680	COG0765	amino acid transport
OTEC02_10685	COG0765	amino acid transport
OTEC02_10715	COG1464	Belongs to the NlpA lipoprotein family
OTEC02_10725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OTEC02_10730	COG2011	ABC-type metal ion transport system permease component
OTEC02_10735	COG0012	GTP binding
OTEC02_10755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OTEC02_10790	COG1917	Cupin 2, conserved barrel domain protein
OTEC02_10790	COG2207	Transcriptional regulator
OTEC02_10795	COG0386	Belongs to the glutathione peroxidase family
OTEC02_10805	COG0436	Aminotransferase
OTEC02_10810	COG1301	dicarboxylic acid transport
OTEC02_10845	COG3634	alkyl hydroperoxide reductase activity
OTEC02_10860	COG0583	DNA-binding transcription factor activity
OTEC02_10865	COG0431	NADPH-dependent FMN reductase
OTEC02_10870	COG0798	PFAM Bile acid sodium symporter
OTEC02_10880	COG0640	Transcriptional regulator
OTEC02_10895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OTEC02_10905	COG0583	DNA-binding transcription factor activity
OTEC02_10915	COG1953	Uracil, thiamine, allantoin
OTEC02_10925	COG2175	clavaminate synthase activity
OTEC02_10930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_10935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OTEC02_10940	COG4521	taurine ABC transporter
OTEC02_10950	COG0477	Major facilitator Superfamily
OTEC02_10975	COG1271	oxidase subunit
OTEC02_10980	COG1294	oxidase, subunit
OTEC02_10990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_11010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OTEC02_11030	COG3052	prosthetic group binding
OTEC02_11035	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OTEC02_11045	COG0583	DNA-binding transcription factor activity
OTEC02_11060	COG2814	Major facilitator Superfamily
OTEC02_11080	COG1346	cytolysis
OTEC02_11090	COG0583	DNA-binding transcription factor activity
OTEC02_11095	COG0625	glutathione transferase activity
OTEC02_11100	COG0625	glutathione transferase activity
OTEC02_11105	COG0583	DNA-binding transcription factor activity
OTEC02_11120	COG1045	serine acetyltransferase
OTEC02_11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OTEC02_11130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OTEC02_11140	COG1280	lysine exporter protein (LysE YggA)
OTEC02_11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_11160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OTEC02_11170	COG0765	amino acid transport
OTEC02_11175	COG0765	amino acid transport
OTEC02_11195	COG0784	Response regulator, receiver
OTEC02_11195	COG2205	protein histidine kinase activity
OTEC02_11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OTEC02_11235	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_11280	COG0583	DNA-binding transcription factor activity
OTEC02_11295	COG2814	Major facilitator Superfamily
OTEC02_11310	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_11315	COG1309	transcriptional regulator
OTEC02_11320	COG1960	acyl-CoA dehydrogenase activity
OTEC02_11325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OTEC02_11330	COG1024	Enoyl-CoA hydratase
OTEC02_11345	COG0583	DNA-binding transcription factor activity
OTEC02_11370	COG2814	Major facilitator Superfamily
OTEC02_11380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OTEC02_11385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OTEC02_11390	COG2814	Major facilitator Superfamily
OTEC02_11395	COG1960	acyl-CoA dehydrogenase activity
OTEC02_11400	COG1024	Enoyl-CoA hydratase
OTEC02_11405	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_11415	COG0183	Belongs to the thiolase family
OTEC02_11425	COG2814	Major facilitator Superfamily
OTEC02_11435	COG1024	Enoyl-CoA hydratase
OTEC02_11450	COG1960	acyl-CoA dehydrogenase activity
OTEC02_11455	COG2814	Major facilitator Superfamily
OTEC02_11460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OTEC02_11480	COG3842	ATPase activity
OTEC02_11485	COG1840	ABC-type Fe3 transport system, periplasmic component
OTEC02_11500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_11505	COG1414	Transcriptional regulator
OTEC02_11510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OTEC02_11515	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_11525	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OTEC02_11535	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_11540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_11575	COG1309	transcriptional regulator
OTEC02_11580	COG1309	transcriptional regulator
OTEC02_11595	COG0702	epimerase
OTEC02_11600	COG1733	regulation of RNA biosynthetic process
OTEC02_11605	COG4221	oxidoreductase activity
OTEC02_11610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OTEC02_11630	COG0300	oxidoreductase activity
OTEC02_11640	COG0534	Mate efflux family protein
OTEC02_11680	COG2050	protein possibly involved in aromatic compounds catabolism
OTEC02_11690	COG3327	negative regulation of DNA-templated transcription, initiation
OTEC02_11695	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OTEC02_11700	COG0183	Belongs to the thiolase family
OTEC02_11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
OTEC02_11710	COG1024	Enoyl-CoA hydratase
OTEC02_11715	COG1024	Enoyl-CoA hydratase
OTEC02_11720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_11725	COG2151	metal-sulfur cluster biosynthetic enzyme
OTEC02_11730	COG3396	Phenylacetate-CoA oxygenase
OTEC02_11735	COG3460	Phenylacetate-CoA oxygenase
OTEC02_11740	COG3396	Phenylacetate-CoA oxygenase
OTEC02_11745	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_11745	COG2030	dehydratase
OTEC02_11750	COG1760	l-serine dehydratase
OTEC02_11755	COG0697	spore germination
OTEC02_11765	COG0789	Transcriptional regulator
OTEC02_11775	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OTEC02_11780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_11795	COG2807	transmembrane transport
OTEC02_11800	COG0590	tRNA wobble adenosine to inosine editing
OTEC02_11810	COG0583	DNA-binding transcription factor activity
OTEC02_11850	COG2885	chlorophyll binding
OTEC02_11850	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OTEC02_11955	COG1116	anion transmembrane transporter activity
OTEC02_11970	COG0864	Transcriptional regulator
OTEC02_11980	COG1733	regulation of RNA biosynthetic process
OTEC02_11985	COG2249	NAD(P)H dehydrogenase (quinone) activity
OTEC02_11990	COG0439	Biotin carboxylase
OTEC02_12005	COG1063	alcohol dehydrogenase
OTEC02_12010	COG1250	3-hydroxyacyl-CoA dehydrogenase
OTEC02_12080	COG0038	chloride channel
OTEC02_12085	COG4770	biotin carboxylase activity
OTEC02_12105	COG1914	H( )-stimulated, divalent metal cation uptake system
OTEC02_12120	COG1595	DNA-templated transcription, initiation
OTEC02_12130	COG3220	belongs to the UPF0276 family
OTEC02_12165	COG0598	Magnesium transport protein CorA
OTEC02_12200	COG1234	tRNA 3'-trailer cleavage
OTEC02_12205	COG1309	transcriptional regulator
OTEC02_12235	COG1595	DNA-templated transcription, initiation
OTEC02_12240	COG3712	iron ion homeostasis
OTEC02_12260	COG0402	S-adenosylhomocysteine deaminase activity
OTEC02_12290	COG3038	cytochrome b561
OTEC02_12295	COG0753	catalase activity
OTEC02_12300	COG1733	regulation of RNA biosynthetic process
OTEC02_12335	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OTEC02_12345	COG4122	O-methyltransferase activity
OTEC02_12355	COG0110	maltose O-acetyltransferase activity
OTEC02_12375	COG1538	Outer membrane efflux protein
OTEC02_12380	COG1137	ATPase activity
OTEC02_12385	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OTEC02_12395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OTEC02_12420	COG1476	TRANSCRIPTIONal
OTEC02_12455	COG3179	chitinase
OTEC02_12555	COG3566	protein conserved in bacteria
OTEC02_12570	COG3567	Phage-associated protein, HI1409 family
OTEC02_12575	COG5410	chromosome segregation
OTEC02_12650	COG3620	sequence-specific DNA binding
OTEC02_12720	COG1733	regulation of RNA biosynthetic process
OTEC02_12725	COG2814	Major facilitator Superfamily
OTEC02_12735	COG0668	transmembrane transport
OTEC02_12775	COG1309	transcriptional regulator
OTEC02_12810	COG2226	methyltransferase
OTEC02_12835	COG1278	Cold shock
OTEC02_12840	COG1560	Kdo2-lipid A biosynthetic process
OTEC02_12845	COG1280	lysine exporter protein (LysE YggA)
OTEC02_12885	COG1570	exodeoxyribonuclease VII activity
OTEC02_12965	COG2871	sodium ion transport
OTEC02_12975	COG0583	DNA-binding transcription factor activity
OTEC02_12985	COG4638	Rieske (2fe-2S)
OTEC02_12995	COG0633	Ferredoxin
OTEC02_12995	COG0543	2 iron, 2 sulfur cluster binding
OTEC02_13000	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_13005	COG3135	benzoate transporter
OTEC02_13010	COG2814	Major facilitator Superfamily
OTEC02_13025	COG1643	Atp-dependent helicase
OTEC02_13030	COG0450	alkyl hydroperoxide reductase
OTEC02_13050	COG3634	alkyl hydroperoxide reductase activity
OTEC02_13070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OTEC02_13090	COG0625	glutathione transferase activity
OTEC02_13100	COG2885	chlorophyll binding
OTEC02_13130	COG1058	Belongs to the CinA family
OTEC02_13130	COG1546	Belongs to the CinA family
OTEC02_13135	COG0542	response to heat
OTEC02_13150	COG1765	OsmC-like protein
OTEC02_13165	COG0667	Aldo Keto reductase
OTEC02_13180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OTEC02_13195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OTEC02_13215	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OTEC02_13225	COG3038	cytochrome b561
OTEC02_13230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OTEC02_13235	COG2252	PERMEase
OTEC02_13245	COG1741	Belongs to the pirin family
OTEC02_13250	COG1309	transcriptional regulator
OTEC02_13260	COG0300	oxidoreductase activity
OTEC02_13265	COG2072	flavoprotein involved in K transport
OTEC02_13270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OTEC02_13275	COG0583	DNA-binding transcription factor activity
OTEC02_13285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_13320	COG1944	ATP diphosphatase activity
OTEC02_13340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_13355	COG2814	Major facilitator Superfamily
OTEC02_13360	COG1024	Enoyl-CoA hydratase
OTEC02_13365	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_13375	COG1960	acyl-CoA dehydrogenase activity
OTEC02_13400	COG2186	Transcriptional regulator
OTEC02_13405	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_13415	COG4948	Mandelate Racemase Muconate Lactonizing
OTEC02_13420	COG2271	Major facilitator Superfamily
OTEC02_13425	COG2721	sulfolactate sulfo-lyase activity
OTEC02_13430	COG0697	spore germination
OTEC02_13460	COG1113	amino acid transport
OTEC02_13480	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_13500	COG0531	amino acid
OTEC02_13510	COG1113	amino acid transport
OTEC02_13545	COG1902	pentaerythritol trinitrate reductase activity
OTEC02_13545	COG0446	pyridine nucleotide-disulphide oxidoreductase
OTEC02_13555	COG3706	GGDEF domain
OTEC02_13555	COG5001	Diguanylate cyclase
OTEC02_13555	COG2203	Gaf domain
OTEC02_13555	COG4251	negative regulation of phosphorylation
OTEC02_13565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OTEC02_13585	COG4172	Belongs to the ABC transporter superfamily
OTEC02_13590	COG4239	(ABC) transporter, permease
OTEC02_13595	COG4174	ABC transporter (Permease)
OTEC02_13600	COG4166	transmembrane transport
OTEC02_13605	COG1388	LysM domain
OTEC02_13605	COG0741	lytic transglycosylase activity
OTEC02_13610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OTEC02_13645	COG0583	DNA-binding transcription factor activity
OTEC02_13650	COG1279	arginine transmembrane transporter activity
OTEC02_13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OTEC02_13680	COG0006	proline dipeptidase activity
OTEC02_13720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OTEC02_13735	COG3384	dioxygenase
OTEC02_13745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OTEC02_13750	COG2878	Part of a membrane complex involved in electron transport
OTEC02_13755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OTEC02_13780	COG0768	penicillin binding
OTEC02_13785	COG0742	ribosomal rna small subunit methyltransferase
OTEC02_13800	COG0830	nickel cation binding
OTEC02_13810	COG0804	urea catabolic process
OTEC02_13835	COG3015	lipoprotein NlpE involved in copper resistance
OTEC02_13850	COG1253	flavin adenine dinucleotide binding
OTEC02_13855	COG2851	Citrate transporter
OTEC02_13895	COG1773	rubredoxin
OTEC02_13900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OTEC02_13905	COG2267	carboxylic ester hydrolase activity
OTEC02_13910	COG0583	DNA-binding transcription factor activity
OTEC02_13940	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OTEC02_13945	COG4181	ATPase activity
OTEC02_13970	COG4771	TonB-dependent receptor
OTEC02_13990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OTEC02_14010	COG0306	phosphate transporter
OTEC02_14020	COG3958	Transketolase
OTEC02_14025	COG3959	Transketolase, thiamine diphosphate binding domain
OTEC02_14030	COG2271	Major facilitator Superfamily
OTEC02_14035	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_14040	COG0583	DNA-binding transcription factor activity
OTEC02_14060	COG2223	nitrite transmembrane transporter activity
OTEC02_14065	COG2207	Transcriptional regulator
OTEC02_14070	COG2066	Belongs to the glutaminase family
OTEC02_14075	COG0242	peptide deformylase activity
OTEC02_14080	COG0477	Major facilitator Superfamily
OTEC02_14095	COG0028	Belongs to the TPP enzyme family
OTEC02_14110	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_14115	COG2267	carboxylic ester hydrolase activity
OTEC02_14125	COG2271	Major facilitator Superfamily
OTEC02_14140	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_14160	COG1414	Transcriptional regulator
OTEC02_14185	COG1215	transferase activity, transferring glycosyl groups
OTEC02_14190	COG0726	polysaccharide deacetylase
OTEC02_14190	COG1649	PFAM Uncharacterised BCR, COG1649
OTEC02_14200	COG4681	YaeQ
OTEC02_14220	COG1607	acyl-coa hydrolase
OTEC02_14230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_14235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OTEC02_14240	COG1309	transcriptional regulator
OTEC02_14265	COG2040	homocysteine
OTEC02_14270	COG0531	amino acid
OTEC02_14325	COG1595	DNA-templated transcription, initiation
OTEC02_14335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_14340	COG0477	Major facilitator Superfamily
OTEC02_14395	COG0405	Gamma-glutamyltransferase
OTEC02_14400	COG2814	Major facilitator Superfamily
OTEC02_14410	COG2050	protein possibly involved in aromatic compounds catabolism
OTEC02_14425	COG1090	epimerase
OTEC02_14445	COG0420	3'-5' exonuclease activity
OTEC02_14470	COG0735	belongs to the Fur family
OTEC02_14475	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_14480	COG2914	Belongs to the UPF0125 (RnfH) family
OTEC02_14500	COG0121	glutamine amidotransferase
OTEC02_14515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OTEC02_14525	COG0210	DNA helicase
OTEC02_14530	COG2885	chlorophyll binding
OTEC02_14535	COG0204	Acyl-transferase
OTEC02_14550	COG2894	cell division
OTEC02_14565	COG1280	lysine exporter protein (LysE YggA)
OTEC02_14570	COG1674	ftsk spoiiie
OTEC02_14575	COG0492	ferredoxin-NADP+ reductase activity
OTEC02_14580	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OTEC02_14590	COG0456	acetyltransferase
OTEC02_14605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OTEC02_14610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OTEC02_14620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OTEC02_14645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OTEC02_14645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OTEC02_14665	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_14670	COG4638	Rieske (2fe-2S)
OTEC02_14685	COG0473	3-isopropylmalate dehydrogenase activity
OTEC02_14690	COG0583	DNA-binding transcription factor activity
OTEC02_14710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OTEC02_14745	COG0358	DNA primase activity
OTEC02_14760	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OTEC02_14790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OTEC02_14820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OTEC02_14830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OTEC02_14830	COG0352	thiamine-phosphate diphosphorylase activity
OTEC02_14830	COG0351	phosphomethylpyrimidine kinase
OTEC02_14835	COG1652	LysM domain
OTEC02_14845	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_14860	COG1399	metal-binding, possibly nucleic acid-binding protein
OTEC02_14865	COG3101	peptidyl-lysine hydroxylation
OTEC02_14870	COG0009	L-threonylcarbamoyladenylate synthase
OTEC02_14875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OTEC02_14880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OTEC02_14895	COG4106	trans-aconitate 2-methyltransferase activity
OTEC02_14910	COG2226	methyltransferase
OTEC02_14910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_14910	COG0596	Alpha beta hydrolase
OTEC02_14920	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OTEC02_14925	COG2223	nitrite transmembrane transporter activity
OTEC02_14945	COG1196	nuclear chromosome segregation
OTEC02_14955	COG0730	response to heat
OTEC02_14970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OTEC02_15035	COG0489	protein tyrosine kinase activity
OTEC02_15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_15045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_15080	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OTEC02_15085	COG2081	HI0933 family
OTEC02_15095	COG0668	transmembrane transport
OTEC02_15115	COG0583	DNA-binding transcription factor activity
OTEC02_15120	COG1278	Cold shock
OTEC02_15135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OTEC02_15140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OTEC02_15170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OTEC02_15195	COG2199	diguanylate cyclase activity
OTEC02_15205	COG2205	protein histidine kinase activity
OTEC02_15210	COG0745	RESPONSE REGULATOR receiver
OTEC02_15225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OTEC02_15265	COG0110	maltose O-acetyltransferase activity
OTEC02_15270	COG0438	transferase activity, transferring glycosyl groups
OTEC02_15325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OTEC02_15330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OTEC02_15340	COG0583	DNA-binding transcription factor activity
OTEC02_15375	COG0583	DNA-binding transcription factor activity
OTEC02_15395	COG0583	DNA-binding transcription factor activity
OTEC02_15400	COG1053	succinate dehydrogenase
OTEC02_15415	COG1309	transcriptional regulator
OTEC02_15425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OTEC02_15430	COG2814	Major facilitator Superfamily
OTEC02_15435	COG1960	acyl-CoA dehydrogenase activity
OTEC02_15440	COG0583	DNA-binding transcription factor activity
OTEC02_15445	COG1063	alcohol dehydrogenase
OTEC02_15475	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OTEC02_15480	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OTEC02_15485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OTEC02_15505	COG2132	Multicopper oxidase
OTEC02_15515	COG0561	phosphatase activity
OTEC02_15520	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OTEC02_15530	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OTEC02_15545	COG1214	PFAM Peptidase M22, glycoprotease
OTEC02_15605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OTEC02_15610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OTEC02_15615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OTEC02_15675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OTEC02_15685	COG1846	Transcriptional regulator
OTEC02_15690	COG1764	response to oxidative stress
OTEC02_15730	COG0037	tRNA processing
OTEC02_15740	COG0248	Ppx GppA phosphatase
OTEC02_15770	COG0072	phenylalanine-tRNA ligase activity
OTEC02_15795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OTEC02_15800	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OTEC02_15815	COG1238	metal cluster binding
OTEC02_15820	COG0625	glutathione transferase activity
OTEC02_15840	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_15845	COG3028	Belongs to the UPF0307 family
OTEC02_15850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OTEC02_15870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OTEC02_15875	COG0617	tRNA 3'-terminal CCA addition
OTEC02_15880	COG1555	photosystem II stabilization
OTEC02_15885	COG3956	TIGRFAM MazG family protein
OTEC02_15895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OTEC02_15915	COG0784	Response regulator, receiver
OTEC02_15915	COG2205	protein histidine kinase activity
OTEC02_15915	COG5002	protein histidine kinase activity
OTEC02_15920	COG1024	Enoyl-CoA hydratase
OTEC02_15925	COG2084	Dehydrogenase
OTEC02_15930	COG3622	Belongs to the hyi family
OTEC02_15945	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OTEC02_15950	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OTEC02_15955	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OTEC02_15960	COG0697	spore germination
OTEC02_15970	COG2814	Major facilitator Superfamily
OTEC02_15975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OTEC02_15985	COG0583	DNA-binding transcription factor activity
OTEC02_15995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OTEC02_16005	COG0084	hydrolase, TatD family'
OTEC02_16020	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OTEC02_16040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OTEC02_16045	COG0440	acetolactate synthase activity
OTEC02_16050	COG0028	Belongs to the TPP enzyme family
OTEC02_16070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OTEC02_16075	COG1136	(ABC) transporter
OTEC02_16075	COG0577	efflux transmembrane transporter activity
OTEC02_16095	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OTEC02_16100	COG1162	GTPase activity
OTEC02_16110	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OTEC02_16120	COG2091	lysine biosynthetic process via aminoadipic acid
OTEC02_16130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OTEC02_16135	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_16175	COG2986	histidine ammonia-lyase
OTEC02_16185	COG1216	Glycosyl transferase, family 2
OTEC02_16200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OTEC02_16205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OTEC02_16225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OTEC02_16245	COG1426	Protein conserved in bacteria
OTEC02_16280	COG0793	Belongs to the peptidase S41A family
OTEC02_16295	COG2267	carboxylic ester hydrolase activity
OTEC02_16305	COG1012	belongs to the aldehyde dehydrogenase family
OTEC02_16310	COG3265	gluconokinase activity
OTEC02_16320	COG0800	Aldolase
OTEC02_16340	COG0857	belongs to the CobB CobQ family
OTEC02_16340	COG0280	phosphate acetyltransferase
OTEC02_16345	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_16345	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OTEC02_16365	COG0740	serine-type endopeptidase activity
OTEC02_16375	COG4774	siderophore transport
OTEC02_16385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OTEC02_16395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OTEC02_16395	COG2813	Specifically methylates the guanine in position
OTEC02_16495	COG0788	formyltetrahydrofolate deformylase activity
OTEC02_16510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OTEC02_16515	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OTEC02_16520	COG4651	solute:proton antiporter activity
OTEC02_16520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OTEC02_16540	COG0724	RNA recognition motif
OTEC02_16545	COG0210	DNA helicase
OTEC02_16570	COG1733	regulation of RNA biosynthetic process
OTEC02_16580	COG2900	Belongs to the SlyX family
OTEC02_16595	COG1560	Kdo2-lipid A biosynthetic process
OTEC02_16605	COG1301	dicarboxylic acid transport
OTEC02_16660	COG0473	3-isopropylmalate dehydrogenase activity
OTEC02_16685	COG0583	DNA-binding transcription factor activity
OTEC02_16725	COG0583	DNA-binding transcription factor activity
OTEC02_16735	COG0625	glutathione transferase activity
OTEC02_16740	COG2378	regulation of single-species biofilm formation
OTEC02_16745	COG0546	phosphoglycolate phosphatase activity
OTEC02_16760	COG1530	ribonuclease E activity
OTEC02_16780	COG0583	DNA-binding transcription factor activity
OTEC02_16785	COG4221	oxidoreductase activity
OTEC02_16790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OTEC02_16800	COG0534	Mate efflux family protein
OTEC02_16815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OTEC02_16840	COG0493	'glutamate synthase
OTEC02_16850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OTEC02_16855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OTEC02_16870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OTEC02_16880	COG0644	oxidoreductase
OTEC02_16880	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OTEC02_16895	COG4535	Mg2 and Co2 transporter CorC
OTEC02_16905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_16905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OTEC02_16925	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OTEC02_16935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OTEC02_16945	COG0484	heat shock protein binding
OTEC02_16950	COG0789	Transcriptional regulator
OTEC02_16955	COG0598	Magnesium transport protein CorA
OTEC02_16960	COG1185	polyribonucleotide nucleotidyltransferase activity
OTEC02_16975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OTEC02_16980	COG1074	ATP-dependent DNA helicase activity
OTEC02_16985	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OTEC02_17005	COG2226	methyltransferase
OTEC02_17015	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OTEC02_17025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OTEC02_17040	COG2111	Na H antiporter
OTEC02_17040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OTEC02_17045	COG1006	Multisubunit Na H antiporter MnhC subunit
OTEC02_17050	COG0651	ATP synthesis coupled electron transport
OTEC02_17060	COG2212	antiporter activity
OTEC02_17070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OTEC02_17080	COG0195	Participates in both transcription termination and antitermination
OTEC02_17130	COG0237	dephospho-CoA kinase activity
OTEC02_17140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OTEC02_17155	COG0497	DNA recombination
OTEC02_17165	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OTEC02_17200	COG2169	Transcriptional regulator
OTEC02_17200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OTEC02_17205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OTEC02_17275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OTEC02_17290	COG0326	Molecular chaperone. Has ATPase activity
OTEC02_17305	COG2056	Na+-H+ antiporter family
OTEC02_17375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OTEC02_17405	COG0546	phosphoglycolate phosphatase activity
OTEC02_17410	COG1716	ATPase activity
OTEC02_17455	COG0181	hydroxymethylbilane synthase activity
OTEC02_17465	COG3275	phosphorelay sensor kinase activity
OTEC02_17485	COG1538	Outer membrane efflux protein
OTEC02_17495	COG0697	spore germination
OTEC02_17515	COG0494	nUDIX hydrolase
OTEC02_17520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OTEC02_17525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OTEC02_17530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OTEC02_17535	COG0772	Belongs to the SEDS family
OTEC02_17560	COG4974	Belongs to the 'phage' integrase family
OTEC02_17565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_17575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OTEC02_17585	COG2197	response regulator
OTEC02_17600	COG0793	Belongs to the peptidase S41A family
OTEC02_17605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OTEC02_17610	COG0795	lipopolysaccharide-transporting ATPase activity
OTEC02_17615	COG0795	lipopolysaccharide-transporting ATPase activity
OTEC02_17650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OTEC02_17650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OTEC02_17660	COG0004	ammonium transporteR
OTEC02_17665	COG0347	Belongs to the P(II) protein family
OTEC02_17675	COG0606	chelatase, subunit chli
OTEC02_17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OTEC02_17690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OTEC02_17710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OTEC02_17725	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_17735	COG0477	Major facilitator Superfamily
OTEC02_17740	COG2860	membrane
OTEC02_17750	COG1253	flavin adenine dinucleotide binding
OTEC02_17765	COG2814	Major facilitator Superfamily
OTEC02_17775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OTEC02_17810	COG0655	NAD(P)H dehydrogenase (quinone) activity
OTEC02_17820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OTEC02_17890	COG0758	DNA mediated transformation
OTEC02_17900	COG0697	spore germination
OTEC02_17905	COG1309	transcriptional regulator
OTEC02_17920	COG0386	Belongs to the glutathione peroxidase family
OTEC02_17940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OTEC02_17950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OTEC02_17990	COG1121	(ABC) transporter
OTEC02_17995	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OTEC02_18000	COG1280	lysine exporter protein (LysE YggA)
OTEC02_18005	COG2837	iron assimilation
OTEC02_18010	COG0281	malic enzyme
OTEC02_18060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OTEC02_18060	COG0519	Catalyzes the synthesis of GMP from XMP
OTEC02_18065	COG4399	Belongs to the UPF0754 family
OTEC02_18070	COG2259	Doxx family
OTEC02_18075	COG0586	Pfam SNARE associated Golgi protein
OTEC02_18090	COG1192	Involved in chromosome partitioning
OTEC02_18100	COG0271	Belongs to the BolA IbaG family
OTEC02_18140	COG3321	synthase
OTEC02_18140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OTEC02_18140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OTEC02_18140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OTEC02_18145	COG1960	acyl-CoA dehydrogenase activity
OTEC02_18150	COG0318	PFAM AMP-dependent synthetase and ligase
OTEC02_18155	COG2197	response regulator
OTEC02_18165	COG3916	Acyl-homoserine-lactone synthase
OTEC02_18170	COG0477	Major facilitator Superfamily
OTEC02_18175	COG1024	Enoyl-CoA hydratase
OTEC02_18180	COG1024	Enoyl-CoA hydratase
OTEC02_18185	COG1960	acyl-CoA dehydrogenase activity
OTEC02_18190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OTEC02_18230	COG1113	amino acid transport
OTEC02_18235	COG1113	amino acid transport
OTEC02_18240	COG0251	oxidation-reduction process
OTEC02_18255	COG1522	sequence-specific DNA binding
OTEC02_18280	COG0564	pseudouridine synthase activity
OTEC02_18360	COG1051	belongs to the nudix hydrolase family
OTEC02_18380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OTEC02_18395	COG1802	Transcriptional regulator
OTEC02_18405	COG1448	Aminotransferase
OTEC02_18420	COG2186	Transcriptional regulator
OTEC02_18430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OTEC02_18435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_18450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OTEC02_18460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OTEC02_18470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OTEC02_18480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OTEC02_18510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OTEC02_18540	COG0728	peptidoglycan biosynthetic process
OTEC02_18545	COG3023	N-Acetylmuramoyl-L-alanine amidase
OTEC02_18580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OTEC02_18580	COG1017	nitric oxide dioxygenase activity
OTEC02_18605	COG0546	phosphoglycolate phosphatase activity
OTEC02_18610	COG1028	Short-chain dehydrogenase reductase Sdr
OTEC02_18625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OTEC02_18625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OTEC02_18630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_18635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OTEC02_18640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OTEC02_18645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OTEC02_18650	COG1116	anion transmembrane transporter activity
OTEC02_18655	COG1309	transcriptional regulator
OTEC02_18660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OTEC02_18670	COG0196	riboflavin kinase activity
OTEC02_18675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OTEC02_18685	COG1047	Peptidyl-prolyl cis-trans
OTEC02_18725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OTEC02_18780	COG2951	lytic endotransglycosylase activity
OTEC02_18785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OTEC02_18800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OTEC02_18810	COG0671	phosphoesterase, PA-phosphatase related
OTEC02_18815	COG0861	Integral membrane protein TerC family
OTEC02_18830	COG0754	glutathionylspermidine amidase activity
OTEC02_18840	COG0402	S-adenosylhomocysteine deaminase activity
OTEC02_18855	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OTEC02_18860	COG1230	cation diffusion facilitator family transporter
OTEC02_18875	COG0706	membrane insertase activity
OTEC02_18890	COG0230	Belongs to the bacterial ribosomal protein bL34 family