locus-tag	class	description
EVX74_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVX74_000010	COG0592	DNA-directed DNA polymerase activity
EVX74_000020	COG0187	DNA topoisomerase II activity
EVX74_000025	COG1063	alcohol dehydrogenase
EVX74_000030	COG0488	(ABC) transporter
EVX74_000090	COG0657	acetylesterase activity
EVX74_000105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EVX74_000135	COG2814	Major facilitator Superfamily
EVX74_000140	COG2814	Major facilitator Superfamily
EVX74_000170	COG0693	protein deglycase activity
EVX74_000180	COG1012	belongs to the aldehyde dehydrogenase family
EVX74_000185	COG0733	neurotransmitter:sodium symporter activity
EVX74_000195	COG0428	transporter
EVX74_000210	COG0129	dihydroxy-acid dehydratase activity
EVX74_000235	COG0129	dihydroxy-acid dehydratase activity
EVX74_000255	COG2233	PERMEase
EVX74_000265	COG1309	transcriptional regulator
EVX74_000310	COG1064	alcohol dehydrogenase
EVX74_000315	COG2818	Glycosylase
EVX74_000325	COG0739	heme binding
EVX74_000330	COG1194	a g-specific adenine glycosylase
EVX74_000360	COG1596	polysaccharide export
EVX74_000385	COG2433	Pfam Transposase IS66
EVX74_000420	COG2433	Pfam Transposase IS66
EVX74_000430	COG1086	Polysaccharide biosynthesis protein
EVX74_000435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EVX74_000440	COG1083	cytidylyl-transferase
EVX74_000450	COG2030	dehydratase
EVX74_000455	COG2089	acid synthase
EVX74_000460	COG1215	transferase activity, transferring glycosyl groups
EVX74_000485	COG1216	Glycosyl transferase, family 2
EVX74_000495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVX74_000510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EVX74_000525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVX74_000530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVX74_000570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EVX74_000580	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EVX74_000585	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EVX74_000595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EVX74_000625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVX74_000650	COG1203	CRISPR-associated helicase, Cas3
EVX74_000660	COG4628	conserved protein (DUF2132)
EVX74_000680	COG3540	Alkaline phosphatase
EVX74_000695	COG0737	Belongs to the 5'-nucleotidase family
EVX74_000705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EVX74_000745	COG0494	nUDIX hydrolase
EVX74_000785	COG2826	transposase and inactivated derivatives, IS30 family
EVX74_000800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVX74_000805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVX74_000810	COG3138	arginine N-succinyltransferase
EVX74_000815	COG1012	belongs to the aldehyde dehydrogenase family
EVX74_000820	COG3724	N-succinylarginine dihydrolase activity
EVX74_000830	COG1113	amino acid transport
EVX74_000930	COG1538	Outer membrane efflux protein
EVX74_000960	COG4372	Transposase
EVX74_000985	COG3756	Protein conserved in bacteria
EVX74_001015	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVX74_001020	COG0753	catalase activity
EVX74_001045	COG3756	Protein conserved in bacteria
EVX74_001075	COG0271	Belongs to the BolA IbaG family
EVX74_001085	COG1192	Involved in chromosome partitioning
EVX74_001100	COG0586	Pfam SNARE associated Golgi protein
EVX74_001105	COG0519	Catalyzes the synthesis of GMP from XMP
EVX74_001105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EVX74_001110	COG1715	Restriction endonuclease
EVX74_001115	COG3706	GGDEF domain
EVX74_001120	COG3706	GGDEF domain
EVX74_001130	COG0625	glutathione transferase activity
EVX74_001155	COG0534	Mate efflux family protein
EVX74_001160	COG0436	Aminotransferase
EVX74_001175	COG2837	iron assimilation
EVX74_001185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EVX74_001190	COG1121	(ABC) transporter
EVX74_001240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EVX74_001255	COG1012	belongs to the aldehyde dehydrogenase family
EVX74_001270	COG0386	Belongs to the glutathione peroxidase family
EVX74_001275	COG0697	spore germination
EVX74_001285	COG0758	DNA mediated transformation
EVX74_001335	COG2814	Major facilitator Superfamily
EVX74_001355	COG0477	Major facilitator Superfamily
EVX74_001360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVX74_001395	COG1253	flavin adenine dinucleotide binding
EVX74_001405	COG2860	membrane
EVX74_001410	COG0477	Major facilitator Superfamily
EVX74_001420	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_001435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EVX74_001450	COG0606	chelatase, subunit chli
EVX74_001505	COG0633	Ferredoxin
EVX74_001545	COG2814	Major facilitator Superfamily
EVX74_001575	COG0789	Transcriptional regulator
EVX74_001585	COG0640	Transcriptional regulator
EVX74_001595	COG1230	cation diffusion facilitator family transporter
EVX74_001600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_001690	COG0347	Belongs to the P(II) protein family
EVX74_001695	COG0004	ammonium transporteR
EVX74_001705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVX74_001705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EVX74_001720	COG0586	Pfam SNARE associated Golgi protein
EVX74_001740	COG0795	lipopolysaccharide-transporting ATPase activity
EVX74_001745	COG0795	lipopolysaccharide-transporting ATPase activity
EVX74_001750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EVX74_001755	COG0793	Belongs to the peptidase S41A family
EVX74_001755	COG3409	Peptidoglycan-binding domain 1 protein
EVX74_001765	COG4191	Histidine kinase
EVX74_001770	COG2197	response regulator
EVX74_001775	COG1686	Belongs to the peptidase S11 family
EVX74_001780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EVX74_001790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVX74_001795	COG4974	Belongs to the 'phage' integrase family
EVX74_001820	COG0772	Belongs to the SEDS family
EVX74_001830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVX74_001835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EVX74_001845	COG0494	nUDIX hydrolase
EVX74_001870	COG1132	(ABC) transporter
EVX74_001880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EVX74_001890	COG0497	DNA recombination
EVX74_001895	COG3123	guanosine phosphorylase activity
EVX74_001900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVX74_001910	COG0237	dephospho-CoA kinase activity
EVX74_001960	COG0779	Required for maturation of 30S ribosomal subunits
EVX74_001965	COG0195	Participates in both transcription termination and antitermination
EVX74_001975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EVX74_001980	COG1320	monovalent cation:proton antiporter activity
EVX74_001985	COG2212	antiporter activity
EVX74_001990	COG1863	multisubunit Na H antiporter MnhE subunit
EVX74_001995	COG0651	ATP synthesis coupled electron transport
EVX74_002000	COG1006	Multisubunit Na H antiporter MnhC subunit
EVX74_002005	COG2111	Na H antiporter
EVX74_002005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVX74_002020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EVX74_002025	COG4221	oxidoreductase activity
EVX74_002030	COG2873	o-acetylhomoserine
EVX74_002040	COG0488	(ABC) transporter
EVX74_002060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EVX74_002075	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EVX74_002095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EVX74_002100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EVX74_002105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EVX74_002110	COG2226	methyltransferase
EVX74_002160	COG0067	glutamate synthase
EVX74_002160	COG0069	glutamate synthase activity
EVX74_002160	COG0070	glutamate synthase
EVX74_002165	COG0493	'glutamate synthase
EVX74_002170	COG1704	LemA family
EVX74_002195	COG3307	-O-antigen
EVX74_002215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVX74_002220	COG1758	RNA polymerase activity
EVX74_002225	COG0194	GDP metabolic process
EVX74_002265	COG0228	four-way junction DNA binding
EVX74_002270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EVX74_002280	COG0335	large ribosomal subunit rRNA binding
EVX74_002295	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EVX74_002300	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EVX74_002305	COG5380	lipid catabolic process
EVX74_002310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EVX74_002360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVX74_002365	COG0277	FAD linked oxidase domain protein
EVX74_002385	COG2814	Major facilitator Superfamily
EVX74_002390	COG1289	transmembrane transporter activity
EVX74_002400	COG0628	permease
EVX74_002435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EVX74_002440	COG0254	rRNA binding
EVX74_002445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EVX74_002455	COG0534	Mate efflux family protein
EVX74_002465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVX74_002485	COG1278	Cold shock
EVX74_002490	COG1960	acyl-CoA dehydrogenase activity
EVX74_002510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EVX74_002530	COG0513	Belongs to the DEAD box helicase family
EVX74_002535	COG1127	ABC transporter
EVX74_002540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EVX74_002545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EVX74_002560	COG0598	Magnesium transport protein CorA
EVX74_002570	COG0494	nUDIX hydrolase
EVX74_002575	COG1040	competence protein
EVX74_002580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EVX74_002590	COG2937	Belongs to the GPAT DAPAT family
EVX74_002595	COG1946	Acyl-CoA thioesterase
EVX74_002600	COG1301	dicarboxylic acid transport
EVX74_002610	COG1959	2 iron, 2 sulfur cluster binding
EVX74_002615	COG1017	nitric oxide dioxygenase activity
EVX74_002615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVX74_002620	COG0433	COG0433 Predicted ATPase
EVX74_002625	COG0626	cystathionine gamma-synthase activity
EVX74_002645	COG0088	Forms part of the polypeptide exit tunnel
EVX74_002650	COG0089	rRNA binding
EVX74_002660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EVX74_002710	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EVX74_002715	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EVX74_002725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EVX74_002750	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EVX74_002760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EVX74_002765	COG0202	RNA polymerase activity
EVX74_002770	COG0203	ribosomal protein L17
EVX74_002775	COG2072	flavoprotein involved in K transport
EVX74_002780	COG1960	acyl-CoA dehydrogenase activity
EVX74_002785	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EVX74_002810	COG0697	spore germination
EVX74_002820	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EVX74_002825	COG0339	signal peptide processing
EVX74_002835	COG0557	exoribonuclease II activity
EVX74_002870	COG0179	Fumarylacetoacetate (FAA) hydrolase
EVX74_002890	COG1295	ribonuclease BN
EVX74_002960	COG1702	phosphate starvation-inducible protein PhoH
EVX74_002965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EVX74_002970	COG0741	lytic transglycosylase activity
EVX74_002970	COG1196	nuclear chromosome segregation
EVX74_002970	COG0739	heme binding
EVX74_003010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EVX74_003015	COG1183	phosphatidylcholine synthase activity
EVX74_003075	COG1607	acyl-coa hydrolase
EVX74_003110	COG2350	Protein conserved in bacteria
EVX74_003125	COG3781	membrane
EVX74_003130	COG2003	Belongs to the UPF0758 family
EVX74_003135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EVX74_003145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EVX74_003155	COG2814	Major facilitator Superfamily
EVX74_003180	COG3622	Belongs to the hyi family
EVX74_003185	COG2084	Dehydrogenase
EVX74_003200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVX74_003215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EVX74_003235	COG1862	Preprotein translocase
EVX74_003250	COG1704	LemA family
EVX74_003260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EVX74_003320	COG0285	dihydrofolate synthase activity
EVX74_003335	COG0450	alkyl hydroperoxide reductase
EVX74_003340	COG0653	protein targeting
EVX74_003350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EVX74_003355	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EVX74_003410	COG2969	positive regulation of protein catabolic process
EVX74_003415	COG0625	glutathione transferase activity
EVX74_003420	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EVX74_003425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EVX74_003430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EVX74_003435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EVX74_003440	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EVX74_003490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EVX74_003500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVX74_003505	COG1408	metallophosphoesterase
EVX74_003515	COG0477	Major facilitator Superfamily
EVX74_003520	COG1272	protein, Hemolysin III
EVX74_003540	COG1024	Enoyl-CoA hydratase
EVX74_003540	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVX74_003545	COG0183	Belongs to the thiolase family
EVX74_003550	COG2207	Transcriptional regulator
EVX74_003555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EVX74_003560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVX74_003580	COG0183	Belongs to the thiolase family
EVX74_003600	COG0833	amino acid
EVX74_003610	COG2233	PERMEase
EVX74_003615	COG1217	gtp-binding protein TYPA
EVX74_003640	COG1902	pentaerythritol trinitrate reductase activity
EVX74_003650	COG3385	transposase activity
EVX74_003665	COG0354	folic acid binding
EVX74_003735	COG0564	pseudouridine synthase activity
EVX74_003760	COG2824	Alkylphosphonate utilization operon protein PhnA
EVX74_003775	COG0628	permease
EVX74_003785	COG0351	phosphomethylpyrimidine kinase
EVX74_003785	COG0352	thiamine-phosphate diphosphorylase activity
EVX74_003785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVX74_003795	COG3293	Transposase
EVX74_003805	COG3152	Membrane
EVX74_003820	COG4772	TonB-dependent receptor
EVX74_003825	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVX74_003835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EVX74_003835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EVX74_003840	COG0745	RESPONSE REGULATOR receiver
EVX74_003845	COG2205	protein histidine kinase activity
EVX74_003855	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVX74_003875	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EVX74_003890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVX74_003900	COG0713	ATP synthesis coupled electron transport
EVX74_003905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EVX74_003910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EVX74_003975	COG0583	DNA-binding transcription factor activity
EVX74_003995	COG0531	amino acid
EVX74_004000	COG4303	Ethanolamine ammonia lyase large subunit
EVX74_004005	COG4302	ethanolamine ammonia-lyase activity
EVX74_004015	COG0668	transmembrane transport
EVX74_004030	COG2081	HI0933 family
EVX74_004040	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EVX74_004060	COG0004	ammonium transporteR
EVX74_004065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVX74_004080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVX74_004080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EVX74_004100	COG0489	protein tyrosine kinase activity
EVX74_004145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_004200	COG2832	Protein of unknown function (DUF454)
EVX74_004260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EVX74_004270	COG1289	transmembrane transporter activity
EVX74_004285	COG0786	glutamate:sodium symporter activity
EVX74_004290	COG1115	amino acid carrier protein
EVX74_004295	COG2059	Chromate
EVX74_004300	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVX74_004310	COG1607	acyl-coa hydrolase
EVX74_004325	COG0583	DNA-binding transcription factor activity
EVX74_004345	COG0523	cobalamin synthesis protein
EVX74_004350	COG4681	YaeQ
EVX74_004365	COG3706	GGDEF domain
EVX74_004365	COG4251	negative regulation of phosphorylation
EVX74_004365	COG5001	Diguanylate cyclase
EVX74_004365	COG2203	Gaf domain
EVX74_004395	COG0393	Putative heavy-metal-binding
EVX74_004400	COG0393	Putative heavy-metal-binding
EVX74_004415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_004420	COG0671	phosphoesterase, PA-phosphatase related
EVX74_004435	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EVX74_004445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EVX74_004455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EVX74_004460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EVX74_004460	COG1648	precorrin-2 dehydrogenase activity
EVX74_004465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EVX74_004475	COG0531	amino acid
EVX74_004490	COG0321	lipoyl(octanoyl) transferase activity
EVX74_004495	COG2921	Belongs to the UPF0250 family
EVX74_004520	COG0586	Pfam SNARE associated Golgi protein
EVX74_004545	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EVX74_004570	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EVX74_004575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EVX74_004590	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EVX74_004600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EVX74_004605	COG0358	DNA primase activity
EVX74_004615	COG0564	pseudouridine synthase activity
EVX74_004640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EVX74_004665	COG0251	oxidation-reduction process
EVX74_004670	COG1309	transcriptional regulator
EVX74_004680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EVX74_004685	COG0505	Belongs to the CarA family
EVX74_004715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVX74_004730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EVX74_004765	COG1253	flavin adenine dinucleotide binding
EVX74_004785	COG2239	Acts as a magnesium transporter
EVX74_004795	COG0501	Belongs to the peptidase M48B family
EVX74_004800	COG1196	nuclear chromosome segregation
EVX74_004800	COG0741	lytic transglycosylase activity
EVX74_004800	COG0739	heme binding
EVX74_004805	COG0037	tRNA processing
EVX74_004820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EVX74_004840	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EVX74_004850	COG0280	phosphate acetyltransferase
EVX74_004850	COG0281	malic enzyme
EVX74_004855	COG1716	ATPase activity
EVX74_004855	COG5001	Diguanylate cyclase
EVX74_004860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EVX74_004865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EVX74_004870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EVX74_004915	COG1115	amino acid carrier protein
EVX74_004920	COG1113	amino acid transport
EVX74_004930	COG0019	diaminopimelate decarboxylase activity
EVX74_004945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EVX74_004955	COG1522	sequence-specific DNA binding
EVX74_004960	COG1280	lysine exporter protein (LysE YggA)
EVX74_005000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_005020	COG1671	Belongs to the UPF0178 family
EVX74_005040	COG1136	(ABC) transporter
EVX74_005045	COG0658	competence protein
EVX74_005045	COG2333	competence protein COMEC
EVX74_005060	COG2267	carboxylic ester hydrolase activity
EVX74_005065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EVX74_005070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EVX74_005075	COG0628	permease
EVX74_005080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EVX74_005110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EVX74_005130	COG0823	Involved in the tonB-independent uptake of proteins
EVX74_005150	COG0824	Thioesterase
EVX74_005155	COG1473	amidohydrolase
EVX74_005170	COG2255	four-way junction helicase activity
EVX74_005200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EVX74_005200	COG0047	phosphoribosylformylglycinamidine synthase activity
EVX74_005230	COG1051	belongs to the nudix hydrolase family
EVX74_005230	COG1056	cytidyltransferase-related domain
EVX74_005245	COG2353	YceI-like domain
EVX74_005250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EVX74_005260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EVX74_005265	COG0602	queuosine metabolic process
EVX74_005285	COG0583	DNA-binding transcription factor activity
EVX74_005290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EVX74_005295	COG4208	sulfate ABC transporter
EVX74_005310	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EVX74_005315	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EVX74_005325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EVX74_005345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVX74_005360	COG0681	Belongs to the peptidase S26 family
EVX74_005370	COG0571	ribonuclease III activity
EVX74_005375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EVX74_005390	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EVX74_005425	COG0436	Aminotransferase
EVX74_005435	COG0052	Belongs to the universal ribosomal protein uS2 family
EVX74_005460	COG2951	lytic endotransglycosylase activity
EVX74_005475	COG0842	Transport permease protein
EVX74_005480	COG1131	(ABC) transporter
EVX74_005490	COG3706	GGDEF domain
EVX74_005525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EVX74_005545	COG3634	alkyl hydroperoxide reductase activity
EVX74_005550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EVX74_005555	COG0826	peptidase U32
EVX74_005585	COG1720	tRNA m6t6A37 methyltransferase activity
EVX74_005595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EVX74_005610	COG0642	Histidine kinase
EVX74_005620	COG0494	nUDIX hydrolase
EVX74_005630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVX74_005635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EVX74_005640	COG3139	Protein of unknown function (DUF1315)
EVX74_005650	COG1301	dicarboxylic acid transport
EVX74_005655	COG1960	acyl-CoA dehydrogenase activity
EVX74_005660	COG0693	protein deglycase activity
EVX74_005670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EVX74_005675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EVX74_005700	COG2252	PERMEase
EVX74_005705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EVX74_005725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EVX74_005735	COG0527	aspartate kinase activity
EVX74_005740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EVX74_005745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EVX74_005760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EVX74_005775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EVX74_005795	COG1252	NADH dehydrogenase
EVX74_005800	COG1686	Belongs to the peptidase S11 family
EVX74_005820	COG2351	hydroxyisourate hydrolase activity
EVX74_005845	COG4372	Transposase
EVX74_005885	COG0436	Aminotransferase
EVX74_005890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EVX74_005895	COG0386	Belongs to the glutathione peroxidase family
EVX74_005905	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EVX74_005925	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EVX74_005940	COG0012	GTP binding
EVX74_005965	COG0204	Acyl-transferase
EVX74_006015	COG0830	nickel cation binding
EVX74_006030	COG0829	nickel cation binding
EVX74_006035	COG0831	urea catabolic process
EVX74_006050	COG0804	urea catabolic process
EVX74_006115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVX74_006150	COG2351	hydroxyisourate hydrolase activity
EVX74_006155	COG2233	PERMEase
EVX74_006170	COG4266	Belongs to the allantoicase family
EVX74_006175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVX74_006180	COG0583	DNA-binding transcription factor activity
EVX74_006195	COG2233	PERMEase
EVX74_006260	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EVX74_006270	COG3293	Transposase
EVX74_006285	COG1401	restriction endodeoxyribonuclease activity
EVX74_006330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EVX74_006330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EVX74_006335	COG1254	Belongs to the acylphosphatase family
EVX74_006370	COG3634	alkyl hydroperoxide reductase activity
EVX74_006400	COG1643	Atp-dependent helicase
EVX74_006420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVX74_006455	COG0802	atpase or kinase
EVX74_006460	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EVX74_006470	COG1923	regulation of RNA biosynthetic process
EVX74_006475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVX74_006485	COG3178	'Phosphotransferase
EVX74_006490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EVX74_006500	COG1192	Involved in chromosome partitioning
EVX74_006505	COG1475	DNA binding
EVX74_006510	COG0811	peptide transport
EVX74_006520	COG1132	(ABC) transporter
EVX74_006525	COG1663	tetraacyldisaccharide 4'-kinase activity
EVX74_006545	COG0084	hydrolase, TatD family'
EVX74_006550	COG1309	transcriptional regulator
EVX74_006580	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EVX74_006590	COG0590	tRNA wobble adenosine to inosine editing
EVX74_006600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EVX74_006610	COG0776	regulation of translation
EVX74_006630	COG2431	L-lysine efflux transmembrane transporter activity
EVX74_006645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EVX74_006650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EVX74_006670	COG1253	flavin adenine dinucleotide binding
EVX74_006690	COG0308	aminopeptidase N
EVX74_006700	COG0589	response to stress
EVX74_006705	COG0589	response to stress
EVX74_006720	COG3135	benzoate transporter
EVX74_006730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EVX74_006735	COG0583	DNA-binding transcription factor activity
EVX74_006750	COG3385	transposase activity
EVX74_006755	COG0183	Belongs to the thiolase family
EVX74_006760	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_006770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EVX74_006785	COG0824	Thioesterase
EVX74_006790	COG1454	alcohol dehydrogenase
EVX74_006795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EVX74_006815	COG0069	glutamate synthase activity
EVX74_006825	COG2308	Evidence 4 Homologs of previously reported genes of
EVX74_006835	COG1305	Transglutaminase-like
EVX74_006850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EVX74_006855	COG0305	Participates in initiation and elongation during chromosome replication
EVX74_006870	COG0360	Binds together with S18 to 16S ribosomal RNA
EVX74_006880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EVX74_006885	COG1845	cytochrome c oxidase, subunit III
EVX74_006890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EVX74_006895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EVX74_006920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVX74_006935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EVX74_006940	COG2890	protein-(glutamine-N5) methyltransferase activity
EVX74_006960	COG1960	acyl-CoA dehydrogenase activity
EVX74_006965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVX74_006975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EVX74_007005	COG3293	Transposase
EVX74_007020	COG0477	Major facilitator Superfamily
EVX74_007025	COG0729	surface antigen
EVX74_007060	COG3385	transposase activity
EVX74_007070	COG1570	exodeoxyribonuclease VII activity
EVX74_007140	COG0583	DNA-binding transcription factor activity
EVX74_007145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EVX74_007160	COG1902	pentaerythritol trinitrate reductase activity
EVX74_007160	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVX74_007195	COG0148	phosphopyruvate hydratase activity
EVX74_007210	COG0772	Belongs to the SEDS family
EVX74_007215	COG3385	transposase activity
EVX74_007225	COG4890	Cyd operon protein YbgT
EVX74_007230	COG1294	oxidase, subunit
EVX74_007250	COG0537	adenosine 5'-monophosphoramidase activity
EVX74_007280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EVX74_007300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EVX74_007310	COG0133	tryptophan synthase activity
EVX74_007315	COG0517	IMP dehydrogenase activity
EVX74_007345	COG0612	Peptidase, M16
EVX74_007350	COG0552	protein localization to endoplasmic reticulum
EVX74_007365	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EVX74_007400	COG0456	acetyltransferase
EVX74_007405	COG1960	acyl-CoA dehydrogenase activity
EVX74_007425	COG3293	Transposase
EVX74_007475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EVX74_007480	COG0730	response to heat
EVX74_007485	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVX74_007490	COG2207	Transcriptional regulator
EVX74_007495	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVX74_007500	COG1960	acyl-CoA dehydrogenase activity
EVX74_007505	COG2169	Transcriptional regulator
EVX74_007520	COG1271	oxidase subunit
EVX74_007525	COG1294	oxidase, subunit
EVX74_007535	COG1525	nuclease
EVX74_007590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EVX74_007595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVX74_007610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EVX74_007620	COG2801	Transposase and inactivated derivatives
EVX74_007625	COG2801	Transposase and inactivated derivatives
EVX74_007645	COG2814	Major facilitator Superfamily
EVX74_007650	COG0509	glycine decarboxylation via glycine cleavage system
EVX74_007660	COG1132	(ABC) transporter
EVX74_007665	COG0668	transmembrane transport
EVX74_007670	COG3122	Protein conserved in bacteria
EVX74_007690	COG0640	Transcriptional regulator
EVX74_007695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EVX74_007710	COG0789	Transcriptional regulator
EVX74_007725	COG1960	acyl-CoA dehydrogenase activity
EVX74_007730	COG0183	Belongs to the thiolase family
EVX74_007750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVX74_007755	COG0183	Belongs to the thiolase family
EVX74_007760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVX74_007765	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EVX74_007770	COG3135	benzoate transporter
EVX74_007775	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_007780	COG0543	2 iron, 2 sulfur cluster binding
EVX74_007780	COG0633	Ferredoxin
EVX74_007785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EVX74_007790	COG4638	Rieske (2fe-2S)
EVX74_007800	COG4829	muconolactone delta-isomerase
EVX74_007805	COG4948	Mandelate Racemase Muconate Lactonizing
EVX74_007810	COG0583	DNA-binding transcription factor activity
EVX74_007815	COG2814	Major facilitator Superfamily
EVX74_007825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EVX74_007830	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_007860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EVX74_007880	COG0439	Biotin carboxylase
EVX74_007920	COG0864	Transcriptional regulator
EVX74_007930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EVX74_007955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVX74_007960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVX74_007960	COG1116	anion transmembrane transporter activity
EVX74_007970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVX74_007975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVX74_007980	COG0243	molybdopterin cofactor binding
EVX74_007990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EVX74_008000	COG0314	molybdopterin synthase activity
EVX74_008005	COG0315	cyclic pyranopterin monophosphate synthase activity
EVX74_008005	COG0521	Mo-molybdopterin cofactor biosynthetic process
EVX74_008010	COG0303	'Molybdopterin
EVX74_008015	COG0725	ABC transporter, periplasmic molybdate-binding protein
EVX74_008020	COG4149	molybdate abc transporter
EVX74_008025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EVX74_008030	COG2223	nitrite transmembrane transporter activity
EVX74_008035	COG3293	Transposase
EVX74_008055	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EVX74_008060	COG2116	formate transmembrane transporter activity
EVX74_008065	COG0515	serine threonine protein kinase
EVX74_008080	COG0583	DNA-binding transcription factor activity
EVX74_008095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EVX74_008100	COG1309	transcriptional regulator
EVX74_008120	COG1944	ATP diphosphatase activity
EVX74_008125	COG0644	oxidoreductase
EVX74_008125	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EVX74_008135	COG1960	acyl-CoA dehydrogenase activity
EVX74_008140	COG1960	acyl-CoA dehydrogenase activity
EVX74_008145	COG2814	Major facilitator Superfamily
EVX74_008150	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EVX74_008155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVX74_008160	COG5001	Diguanylate cyclase
EVX74_008165	COG2814	Major facilitator Superfamily
EVX74_008175	COG2814	Major facilitator Superfamily
EVX74_008180	COG1024	Enoyl-CoA hydratase
EVX74_008185	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVX74_008190	COG0183	Belongs to the thiolase family
EVX74_008200	COG0235	Class ii aldolase
EVX74_008205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EVX74_008210	COG1024	Enoyl-CoA hydratase
EVX74_008220	COG1960	acyl-CoA dehydrogenase activity
EVX74_008235	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_008245	COG2814	Major facilitator Superfamily
EVX74_008265	COG0583	DNA-binding transcription factor activity
EVX74_008280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVX74_008285	COG1960	acyl-CoA dehydrogenase activity
EVX74_008290	COG1024	Enoyl-CoA hydratase
EVX74_008305	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_008325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVX74_008330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVX74_008335	COG1012	belongs to the aldehyde dehydrogenase family
EVX74_008360	COG2194	sulfuric ester hydrolase activity
EVX74_008365	COG0745	RESPONSE REGULATOR receiver
EVX74_008370	COG0642	Histidine kinase
EVX74_008465	COG4372	Transposase
EVX74_008585	COG2801	Transposase and inactivated derivatives
EVX74_008600	COG0596	Alpha beta hydrolase
EVX74_008630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EVX74_008665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EVX74_008670	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EVX74_008680	COG0439	Biotin carboxylase
EVX74_008700	COG2814	Major facilitator Superfamily
EVX74_008705	COG0753	catalase activity
EVX74_008760	COG0372	Belongs to the citrate synthase family
EVX74_008790	COG0542	response to heat
EVX74_008795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EVX74_008815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EVX74_008820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EVX74_008825	COG0569	domain protein
EVX74_008830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EVX74_008850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EVX74_008860	COG1585	Membrane protein implicated in regulation of membrane protease activity
EVX74_008880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EVX74_008885	COG0776	regulation of translation
EVX74_008910	COG0822	iron-sulfur transferase activity
EVX74_008915	COG0316	Belongs to the HesB IscA family
EVX74_008945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EVX74_008955	COG1027	Aspartate ammonia-lyase
EVX74_008960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVX74_008990	COG3781	membrane
EVX74_009025	COG0778	Nitroreductase
EVX74_009035	COG0697	spore germination
EVX74_009060	COG0424	maF-like protein
EVX74_009065	COG2850	peptidyl-arginine hydroxylation
EVX74_009070	COG4585	Histidine kinase
EVX74_009075	COG2197	response regulator
EVX74_009085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EVX74_009090	COG0702	epimerase
EVX74_009095	COG0268	Binds directly to 16S ribosomal RNA
EVX74_009110	COG1011	Hydrolase
EVX74_009115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EVX74_009120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EVX74_009125	COG2137	regulation of response to DNA damage stimulus
EVX74_009140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVX74_009145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EVX74_009150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EVX74_009160	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EVX74_009175	COG0575	Belongs to the CDS family
EVX74_009180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EVX74_009200	COG3852	Histidine kinase
EVX74_009215	COG2814	Major facilitator Superfamily
EVX74_009220	COG2814	Major facilitator Superfamily
EVX74_009255	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EVX74_009260	COG0138	bifunctional purine biosynthesis protein purh
EVX74_009265	COG0151	Belongs to the GarS family
EVX74_009295	COG1464	Belongs to the NlpA lipoprotein family
EVX74_009300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EVX74_009305	COG2011	ABC-type metal ion transport system permease component
EVX74_009340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EVX74_009350	COG4122	O-methyltransferase activity
EVX74_009385	COG1137	ATPase activity
EVX74_009390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EVX74_009400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EVX74_009405	COG0517	IMP dehydrogenase activity
EVX74_009405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EVX74_009435	COG0625	glutathione transferase activity
EVX74_009445	COG0505	Belongs to the CarA family
EVX74_009465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EVX74_009475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EVX74_009495	COG2391	methyltransferase activity
EVX74_009550	COG1309	transcriptional regulator
EVX74_009600	COG0352	thiamine-phosphate diphosphorylase activity
EVX74_009615	COG3025	triphosphatase activity
EVX74_009650	COG0612	Peptidase, M16
EVX74_009745	COG2199	diguanylate cyclase activity
EVX74_009745	COG2203	Gaf domain
EVX74_009770	COG4783	chaperone-mediated protein folding
EVX74_009785	COG0501	Belongs to the peptidase M48B family
EVX74_009800	COG0167	dihydroorotate dehydrogenase activity
EVX74_009825	COG0778	Nitroreductase
EVX74_009835	COG0513	Belongs to the DEAD box helicase family
EVX74_009840	COG1278	Cold shock
EVX74_009855	COG2363	Small membrane protein
EVX74_009870	COG0625	glutathione transferase activity
EVX74_009875	COG0659	secondary active sulfate transmembrane transporter activity
EVX74_009880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EVX74_009900	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_009905	COG1309	transcriptional regulator
EVX74_009910	COG1960	acyl-CoA dehydrogenase activity
EVX74_009915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EVX74_009920	COG1024	Enoyl-CoA hydratase
EVX74_009925	COG4770	biotin carboxylase activity
EVX74_009940	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVX74_009945	COG2031	fatty acid transporter
EVX74_009960	COG0540	Belongs to the ATCase OTCase family
EVX74_009985	COG0667	Aldo Keto reductase
EVX74_009995	COG1765	OsmC-like protein
EVX74_010000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EVX74_010035	COG0640	Transcriptional regulator
EVX74_010050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EVX74_010055	COG4232	protein-disulfide reductase activity
EVX74_010060	COG0745	RESPONSE REGULATOR receiver
EVX74_010065	COG0642	Histidine kinase
EVX74_010075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EVX74_010080	COG2072	flavoprotein involved in K transport
EVX74_010085	COG0431	NADPH-dependent FMN reductase
EVX74_010090	COG0798	PFAM Bile acid sodium symporter
EVX74_010100	COG0640	Transcriptional regulator
EVX74_010140	COG0714	Associated with various cellular activities
EVX74_010145	COG2879	small protein
EVX74_010150	COG1966	Carbon starvation protein
EVX74_010155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EVX74_010160	COG1509	lysine 2,3-aminomutase activity
EVX74_010185	COG0254	rRNA binding
EVX74_010205	COG1067	ATP-dependent peptidase activity
EVX74_010210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EVX74_010215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EVX74_010220	COG0583	DNA-binding transcription factor activity
EVX74_010230	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EVX74_010250	COG1686	Belongs to the peptidase S11 family
EVX74_010255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EVX74_010270	COG0482	sulfurtransferase activity
EVX74_010300	COG0616	signal peptide processing
EVX74_010305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EVX74_010315	COG0573	inorganic phosphate transmembrane transporter activity
EVX74_010320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVX74_010325	COG0076	glutamate decarboxylase activity
EVX74_010330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EVX74_010340	COG0671	phosphoesterase, PA-phosphatase related
EVX74_010345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EVX74_010360	COG3293	Transposase
EVX74_010370	COG1733	regulation of RNA biosynthetic process
EVX74_010395	COG0556	nucleotide-excision repair
EVX74_010420	COG2175	clavaminate synthase activity
EVX74_010430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVX74_010435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EVX74_010450	COG2084	Dehydrogenase
EVX74_010455	COG2233	PERMEase
EVX74_010460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVX74_010465	COG0251	oxidation-reduction process
EVX74_010470	COG1335	isochorismatase
EVX74_010475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVX74_010480	COG0596	Alpha beta hydrolase
EVX74_010490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EVX74_010495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EVX74_010500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EVX74_010540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EVX74_010555	COG0174	glutamine synthetase
EVX74_010615	COG3385	transposase activity
EVX74_010720	COG0512	Glutamine amidotransferase of anthranilate synthase
EVX74_010725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EVX74_010740	COG0302	gtp cyclohydrolase
EVX74_010755	COG3706	GGDEF domain
EVX74_010770	COG3739	integral membrane protein
EVX74_010785	COG1741	Belongs to the pirin family
EVX74_010810	COG4983	Phage plasmid primase, P4 family domain protein
EVX74_010845	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVX74_010845	COG1902	pentaerythritol trinitrate reductase activity
EVX74_010860	COG5001	Diguanylate cyclase
EVX74_010860	COG3706	GGDEF domain
EVX74_010860	COG2203	Gaf domain
EVX74_010860	COG4251	negative regulation of phosphorylation
EVX74_010865	COG0418	dihydroorotase activity
EVX74_010895	COG0833	amino acid
EVX74_010935	COG4239	(ABC) transporter, permease
EVX74_010940	COG4174	ABC transporter (Permease)
EVX74_010950	COG0741	lytic transglycosylase activity
EVX74_010950	COG1388	LysM domain
EVX74_010950	COG0741	lytic transglycosylase activity
EVX74_010950	COG1388	LysM domain
EVX74_010970	COG0657	acetylesterase activity
EVX74_010985	COG3107	peptidoglycan biosynthetic process
EVX74_011000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVX74_011005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EVX74_011015	COG2155	Conserved Protein
EVX74_011020	COG0006	proline dipeptidase activity
EVX74_011055	COG1802	Transcriptional regulator
EVX74_011080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EVX74_011090	COG2234	aminopeptidase activity
EVX74_011100	COG3384	dioxygenase
EVX74_011110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EVX74_011115	COG2878	Part of a membrane complex involved in electron transport
EVX74_011120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EVX74_011145	COG0768	penicillin binding
EVX74_011150	COG0742	ribosomal rna small subunit methyltransferase
EVX74_011225	COG1597	lipid kinase activity
EVX74_011245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EVX74_011270	COG0604	alcohol dehydrogenase
EVX74_011270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVX74_011270	COG4221	oxidoreductase activity
EVX74_011270	COG3321	synthase
EVX74_011275	COG3118	belongs to the thioredoxin family
EVX74_011305	COG2268	Band 7 protein
EVX74_011320	COG2826	transposase and inactivated derivatives, IS30 family
EVX74_011380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EVX74_011395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EVX74_011400	COG1053	succinate dehydrogenase
EVX74_011405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EVX74_011440	COG0589	response to stress
EVX74_011460	COG2321	neutral zinc metallopeptidase
EVX74_011465	COG2354	Protein conserved in bacteria
EVX74_011490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EVX74_011500	COG1773	rubredoxin
EVX74_011505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EVX74_011510	COG2267	carboxylic ester hydrolase activity
EVX74_011515	COG0583	DNA-binding transcription factor activity
EVX74_011535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EVX74_011545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EVX74_011550	COG4181	ATPase activity
EVX74_011575	COG4771	TonB-dependent receptor
EVX74_011595	COG0306	phosphate transporter
EVX74_011605	COG3293	Transposase
EVX74_011615	COG2852	Protein conserved in bacteria
EVX74_011625	COG2376	Dihydroxyacetone kinase
EVX74_011630	COG2066	Belongs to the glutaminase family
EVX74_011635	COG3706	GGDEF domain
EVX74_011640	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_011650	COG0525	valine-tRNA ligase activity
EVX74_011665	COG2852	Protein conserved in bacteria
EVX74_011680	COG2323	membrane
EVX74_011685	COG0546	phosphoglycolate phosphatase activity
EVX74_011705	COG1752	Esterase of the alpha-beta hydrolase superfamily
EVX74_011720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVX74_011725	COG0142	geranyltranstransferase activity
EVX74_011730	COG2828	Protein conserved in bacteria
EVX74_011735	COG1113	amino acid transport
EVX74_011765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EVX74_011780	COG0424	maF-like protein
EVX74_011785	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EVX74_011790	COG1792	Involved in formation and maintenance of cell shape
EVX74_011795	COG1077	Cell shape determining protein MreB Mrl
EVX74_011800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVX74_011810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EVX74_011840	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EVX74_011855	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EVX74_011860	COG2223	nitrite transmembrane transporter activity
EVX74_011870	COG0500	methyltransferase
EVX74_011895	COG0783	Belongs to the Dps family
EVX74_011900	COG1136	(ABC) transporter
EVX74_011905	COG4591	ABC-type transport system involved in lipoprotein release permease component
EVX74_011910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_011940	COG3177	Filamentation induced by cAMP protein fic
EVX74_011945	COG0583	DNA-binding transcription factor activity
EVX74_011950	COG1960	acyl-CoA dehydrogenase activity
EVX74_011960	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
EVX74_011965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EVX74_011970	COG0583	DNA-binding transcription factor activity
EVX74_011980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EVX74_011985	COG2814	Major facilitator Superfamily
EVX74_011995	COG4829	muconolactone delta-isomerase
EVX74_012000	COG0427	acetyl-CoA hydrolase
EVX74_012005	COG0183	Belongs to the thiolase family
EVX74_012110	COG0582	viral genome integration into host DNA
EVX74_012120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EVX74_012125	COG2050	protein possibly involved in aromatic compounds catabolism
EVX74_012135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EVX74_012140	COG1090	epimerase
EVX74_012150	COG0420	3'-5' exonuclease activity
EVX74_012165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EVX74_012180	COG0735	belongs to the Fur family
EVX74_012185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EVX74_012205	COG0121	glutamine amidotransferase
EVX74_012210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVX74_012215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EVX74_012220	COG0756	dUTP diphosphatase activity
EVX74_012225	COG0210	DNA helicase
EVX74_012230	COG2885	chlorophyll binding
EVX74_012235	COG0204	Acyl-transferase
EVX74_012250	COG2894	cell division
EVX74_012265	COG1674	ftsk spoiiie
EVX74_012265	COG0531	amino acid
EVX74_012270	COG0492	ferredoxin-NADP+ reductase activity
EVX74_012275	COG3385	transposase activity
EVX74_012280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EVX74_012290	COG0456	acetyltransferase
EVX74_012300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVX74_012315	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EVX74_012330	COG1981	membrane
EVX74_012340	COG0251	oxidation-reduction process
EVX74_012360	COG1652	LysM domain
EVX74_012365	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EVX74_012370	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_012375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EVX74_012385	COG1399	metal-binding, possibly nucleic acid-binding protein
EVX74_012390	COG3101	peptidyl-lysine hydroxylation
EVX74_012395	COG0009	L-threonylcarbamoyladenylate synthase
EVX74_012410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EVX74_012415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EVX74_012430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EVX74_012440	COG0339	signal peptide processing
EVX74_012450	COG4166	transmembrane transport
EVX74_012480	COG2193	ferroxidase activity
EVX74_012485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EVX74_012490	COG3385	transposase activity
EVX74_012495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EVX74_012515	COG0730	response to heat
EVX74_012540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EVX74_012550	COG4106	trans-aconitate 2-methyltransferase activity
EVX74_012560	COG3327	negative regulation of DNA-templated transcription, initiation
EVX74_012565	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EVX74_012570	COG0183	Belongs to the thiolase family
EVX74_012575	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVX74_012580	COG1024	Enoyl-CoA hydratase
EVX74_012585	COG1024	Enoyl-CoA hydratase
EVX74_012590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EVX74_012595	COG2151	metal-sulfur cluster biosynthetic enzyme
EVX74_012600	COG3396	Phenylacetate-CoA oxygenase
EVX74_012605	COG3460	Phenylacetate-CoA oxygenase
EVX74_012610	COG3396	Phenylacetate-CoA oxygenase
EVX74_012615	COG2030	dehydratase
EVX74_012615	COG1012	belongs to the aldehyde dehydrogenase family
EVX74_012630	COG2814	Major facilitator Superfamily
EVX74_012645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EVX74_012655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EVX74_012670	COG4269	membrane
EVX74_012675	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EVX74_012690	COG1968	undecaprenyl-diphosphatase activity
EVX74_012695	COG1214	PFAM Peptidase M22, glycoprotease
EVX74_012705	COG0494	nUDIX hydrolase
EVX74_012765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EVX74_012770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EVX74_012835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVX74_012840	COG1764	response to oxidative stress
EVX74_012890	COG0037	tRNA processing
EVX74_012900	COG0248	Ppx GppA phosphatase
EVX74_012925	COG0072	phenylalanine-tRNA ligase activity
EVX74_012960	COG1238	metal cluster binding
EVX74_012970	COG0625	glutathione transferase activity
EVX74_012985	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EVX74_013005	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_013020	COG4206	TonB-dependent receptor
EVX74_013025	COG2096	Adenosyltransferase
EVX74_013040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EVX74_013055	COG0745	RESPONSE REGULATOR receiver
EVX74_013060	COG2205	protein histidine kinase activity
EVX74_013070	COG1960	acyl-CoA dehydrogenase activity
EVX74_013075	COG1960	acyl-CoA dehydrogenase activity
EVX74_013115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EVX74_013170	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EVX74_013175	COG0675	Transposase, IS605 OrfB family
EVX74_013180	COG2205	protein histidine kinase activity
EVX74_013190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVX74_013195	COG1660	Displays ATPase and GTPase activities
EVX74_013210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EVX74_013215	COG0617	tRNA 3'-terminal CCA addition
EVX74_013220	COG1555	photosystem II stabilization
EVX74_013225	COG3956	TIGRFAM MazG family protein
EVX74_013230	COG0300	oxidoreductase activity
EVX74_013245	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EVX74_013265	COG1426	Protein conserved in bacteria
EVX74_013285	COG2975	iron-sulfur cluster assembly
EVX74_013365	COG3293	Transposase
EVX74_013385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EVX74_013390	COG0440	acetolactate synthase activity
EVX74_013395	COG0028	Belongs to the TPP enzyme family
EVX74_013420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_013425	COG1136	(ABC) transporter
EVX74_013425	COG0577	efflux transmembrane transporter activity
EVX74_013440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EVX74_013450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EVX74_013455	COG1162	GTPase activity
EVX74_013465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EVX74_013480	COG0084	hydrolase, TatD family'
EVX74_013495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EVX74_013505	COG0793	Belongs to the peptidase S41A family
EVX74_013520	COG0596	Alpha beta hydrolase
EVX74_013520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVX74_013520	COG2226	methyltransferase
EVX74_013530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EVX74_013535	COG0857	belongs to the CobB CobQ family
EVX74_013535	COG0280	phosphate acetyltransferase
EVX74_013545	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EVX74_013545	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EVX74_013560	COG0740	serine-type endopeptidase activity
EVX74_013570	COG4771	TonB-dependent receptor
EVX74_013575	COG4774	siderophore transport
EVX74_013585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EVX74_013590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVX74_013595	COG2813	Specifically methylates the guanine in position
EVX74_013595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EVX74_013605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EVX74_013705	COG0788	formyltetrahydrofolate deformylase activity
EVX74_013730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EVX74_013730	COG4651	solute:proton antiporter activity
EVX74_013750	COG0210	DNA helicase
EVX74_013755	COG1929	Belongs to the glycerate kinase type-1 family
EVX74_013785	COG2900	Belongs to the SlyX family
EVX74_013790	COG0488	(ABC) transporter
EVX74_013795	COG1560	Kdo2-lipid A biosynthetic process
EVX74_013860	COG0473	3-isopropylmalate dehydrogenase activity
EVX74_013875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EVX74_013885	COG0583	DNA-binding transcription factor activity
EVX74_013925	COG0753	catalase activity
EVX74_013930	COG3011	Protein conserved in bacteria
EVX74_013955	COG0446	pyridine nucleotide-disulphide oxidoreductase
EVX74_013960	COG3384	dioxygenase
EVX74_013980	COG4638	Rieske (2fe-2S)
EVX74_013985	COG0583	DNA-binding transcription factor activity
EVX74_014005	COG4569	acetaldehyde dehydrogenase (acetylating) activity
EVX74_014010	COG3971	2-oxopent-4-enoate hydratase activity
EVX74_014015	COG0546	phosphoglycolate phosphatase activity
EVX74_014020	COG0564	pseudouridine synthase activity
EVX74_014025	COG1530	ribonuclease E activity
EVX74_014030	COG0318	PFAM AMP-dependent synthetase and ligase
EVX74_014055	COG1983	PspC domain protein
EVX74_014065	COG0471	metal ion transport
EVX74_014090	COG0751	glycine-tRNA ligase activity
EVX74_014110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EVX74_014135	COG0493	'glutamate synthase
EVX74_014145	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EVX74_014155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EVX74_014170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EVX74_014180	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EVX74_014180	COG0644	oxidoreductase
EVX74_014185	COG0425	Belongs to the sulfur carrier protein TusA family
EVX74_014190	COG4535	Mg2 and Co2 transporter CorC
EVX74_014195	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EVX74_014215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EVX74_014220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EVX74_014220	COG0475	glutathione-regulated potassium exporter activity
EVX74_014225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EVX74_014235	COG0789	Transcriptional regulator
EVX74_014240	COG2841	Protein conserved in bacteria
EVX74_014245	COG1185	polyribonucleotide nucleotidyltransferase activity
EVX74_014250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EVX74_014255	COG3293	Transposase
EVX74_014260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVX74_014265	COG1074	ATP-dependent DNA helicase activity
EVX74_014270	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EVX74_014300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EVX74_014330	COG0427	acetyl-CoA hydrolase
EVX74_014335	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EVX74_014370	COG0326	Molecular chaperone. Has ATPase activity
EVX74_014380	COG3047	cAMP biosynthetic process
EVX74_014385	COG2056	Na+-H+ antiporter family
EVX74_014405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EVX74_014410	COG0085	RNA polymerase activity
EVX74_014420	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EVX74_014425	COG0081	regulation of translation
EVX74_014450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EVX74_014480	COG0546	phosphoglycolate phosphatase activity
EVX74_014510	COG0824	Thioesterase
EVX74_014530	COG0181	hydroxymethylbilane synthase activity
EVX74_014540	COG3275	phosphorelay sensor kinase activity
EVX74_014555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EVX74_014580	COG1250	3-hydroxyacyl-CoA dehydrogenase
EVX74_014580	COG1024	Enoyl-CoA hydratase
EVX74_014640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EVX74_014675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVX74_014715	COG3158	transport of potassium into the cell
EVX74_014745	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
EVX74_014760	COG1196	nuclear chromosome segregation
EVX74_014775	COG2963	transposase activity
EVX74_014785	COG4372	Transposase
EVX74_014825	COG0514	ATP-dependent DNA helicase (RecQ)
EVX74_014865	COG4372	Transposase
EVX74_014880	COG4372	Transposase
EVX74_014885	COG0456	acetyltransferase
EVX74_014905	COG4372	Transposase
EVX74_014935	COG2814	Major facilitator Superfamily
EVX74_014945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EVX74_014945	COG0351	phosphomethylpyrimidine kinase
EVX74_014945	COG0352	thiamine-phosphate diphosphorylase activity
EVX74_014980	COG3706	GGDEF domain
EVX74_014990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EVX74_015000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EVX74_015005	COG3162	membrane
EVX74_015010	COG0784	Response regulator, receiver
EVX74_015010	COG2205	protein histidine kinase activity
EVX74_015025	COG0431	NADPH-dependent FMN reductase
EVX74_015030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVX74_015045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EVX74_015050	COG3152	Membrane
EVX74_015055	COG0668	transmembrane transport
EVX74_015060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EVX74_015065	COG1519	Transferase
EVX74_015070	COG1902	pentaerythritol trinitrate reductase activity
EVX74_015095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EVX74_015120	COG0426	domain, Protein
EVX74_015120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVX74_015125	COG2119	membrane
EVX74_015130	COG0508	dehydrogenase complex catalyzes the overall conversion of
EVX74_015165	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EVX74_015175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVX74_015190	COG0189	ligase activity
EVX74_015205	COG2132	Multicopper oxidase
EVX74_015220	COG1278	Cold shock
EVX74_015225	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EVX74_015230	COG0708	Exodeoxyribonuclease III
EVX74_015250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EVX74_015285	COG1247	-acetyltransferase
EVX74_015305	COG2205	protein histidine kinase activity
EVX74_015305	COG0784	Response regulator, receiver
EVX74_015330	COG0410	ABC transporter
EVX74_015335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EVX74_015360	COG3150	esterase
EVX74_015370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EVX74_015375	COG2918	glutathione biosynthetic process
EVX74_015390	COG2733	membrane
EVX74_015430	COG0753	catalase activity
EVX74_015475	COG0385	Bile acid
EVX74_015480	COG1335	isochorismatase
EVX74_015485	COG2814	Major facilitator Superfamily
EVX74_015490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EVX74_015500	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EVX74_015505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EVX74_015510	COG5001	Diguanylate cyclase
EVX74_015510	COG3300	MHYT domain
EVX74_015515	COG2983	Belongs to the UPF0260 family
EVX74_015520	COG5487	UPF0391 membrane protein
EVX74_015525	COG0728	peptidoglycan biosynthetic process
EVX74_015530	COG3023	N-Acetylmuramoyl-L-alanine amidase
EVX74_015545	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EVX74_015550	COG1309	transcriptional regulator
EVX74_015555	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVX74_015560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EVX74_015565	COG0546	phosphoglycolate phosphatase activity
EVX74_015570	COG1028	Short-chain dehydrogenase reductase Sdr
EVX74_015595	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EVX74_015595	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EVX74_015615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EVX74_015620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EVX74_015625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EVX74_015630	COG1116	anion transmembrane transporter activity
EVX74_015635	COG1309	transcriptional regulator
EVX74_015645	COG0196	riboflavin kinase activity
EVX74_015650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EVX74_015655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EVX74_015660	COG1047	Peptidyl-prolyl cis-trans
EVX74_015720	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EVX74_015725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EVX74_015730	COG2951	lytic endotransglycosylase activity
EVX74_015735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EVX74_015755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EVX74_015780	COG2388	GCN5-related N-acetyl-transferase
EVX74_015790	COG0861	Integral membrane protein TerC family
EVX74_015800	COG0402	S-adenosylhomocysteine deaminase activity
EVX74_015825	COG3385	transposase activity
EVX74_015835	COG0706	membrane insertase activity
EVX74_015840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EVX74_015845	COG0594	ribonuclease P activity
EVX74_015860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EVX74_015870	COG1061	Type III restriction enzyme res subunit
EVX74_015885	COG1002	Type II restriction enzyme, methylase subunits
EVX74_015920	COG1525	nuclease
EVX74_015970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVX74_016135	COG2826	transposase and inactivated derivatives, IS30 family
EVX74_016145	COG2826	transposase and inactivated derivatives, IS30 family
EVX74_016240	COG2826	transposase and inactivated derivatives, IS30 family
EVX74_016260	COG0673	inositol 2-dehydrogenase activity
EVX74_016270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EVX74_016295	COG0745	RESPONSE REGULATOR receiver
EVX74_016305	COG2433	Pfam Transposase IS66
EVX74_016330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EVX74_016335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_016540	COG1475	DNA binding
EVX74_016545	COG1192	Involved in chromosome partitioning
EVX74_016840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EVX74_016915	COG3077	Addiction module antitoxin, RelB DinJ family
EVX74_016935	COG0488	(ABC) transporter
EVX74_016940	COG3173	Aminoglycoside phosphotransferase
EVX74_016995	COG1660	Displays ATPase and GTPase activities
EVX74_017010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EVX74_017120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EVX74_017155	COG3421	Type III restriction
EVX74_017160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EVX74_017190	COG4372	Transposase
EVX74_017230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EVX74_017250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EVX74_017255	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVX74_017260	COG3657	addiction module killer protein
EVX74_017280	COG3077	Addiction module antitoxin, RelB DinJ family
EVX74_017290	COG3293	Transposase
EVX74_017305	COG0659	secondary active sulfate transmembrane transporter activity
EVX74_017330	COG3293	Transposase
EVX74_017340	COG1192	Involved in chromosome partitioning
EVX74_017360	COG3385	transposase activity
EVX74_017385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EVX74_017390	COG4774	siderophore transport
EVX74_017410	COG1454	alcohol dehydrogenase
EVX74_017430	COG4773	Receptor
EVX74_017450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EVX74_017465	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EVX74_017470	COG2226	methyltransferase
EVX74_017470	COG2267	carboxylic ester hydrolase activity
EVX74_017475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EVX74_017475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EVX74_017485	COG4106	trans-aconitate 2-methyltransferase activity
EVX74_017495	COG0642	Histidine kinase
EVX74_017510	COG2186	Transcriptional regulator
EVX74_017525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EVX74_017525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EVX74_017530	COG1105	Belongs to the carbohydrate kinase PfkB family
EVX74_017535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVX74_017535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EVX74_017535	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EVX74_017545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EVX74_017550	COG3550	peptidyl-serine autophosphorylation
EVX74_017640	COG0730	response to heat
EVX74_017645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EVX74_017650	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EVX74_017670	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EVX74_017730	COG0579	oxidoreductase
EVX74_017755	COG2130	NADP-dependent
EVX74_017760	COG1309	transcriptional regulator
EVX74_017770	COG1902	pentaerythritol trinitrate reductase activity
EVX74_017780	COG1979	alcohol dehydrogenase
EVX74_017795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EVX74_017810	COG0604	alcohol dehydrogenase
EVX74_017810	COG3321	synthase
EVX74_017815	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EVX74_017820	COG0583	DNA-binding transcription factor activity
EVX74_017825	COG4221	oxidoreductase activity
EVX74_017865	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
EVX74_017985	COG2132	Multicopper oxidase
EVX74_018000	COG2205	protein histidine kinase activity
EVX74_018005	COG3174	membrane
EVX74_018010	COG2217	Heavy metal translocating P-type atpase
EVX74_018065	COG2801	Transposase and inactivated derivatives
EVX74_018170	COG3657	addiction module killer protein
EVX74_018175	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EVX74_018235	COG2431	L-lysine efflux transmembrane transporter activity
EVX74_018355	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source