locus-tag	class	description
ABEKA_0002	COG0582	viral genome integration into host DNA
ABEKA_0005	COG4695	Portal protein
ABEKA_0035	COG3646	Phage regulatory protein
ABEKA_0046	COG0582	viral genome integration into host DNA
ABEKA_0047	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABEKA_0048	COG2050	protein possibly involved in aromatic compounds catabolism
ABEKA_0050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABEKA_0054	COG0420	3'-5' exonuclease activity
ABEKA_0060	COG0735	belongs to the Fur family
ABEKA_0061	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABEKA_0062	COG2914	Belongs to the UPF0125 (RnfH) family
ABEKA_0065	COG0121	glutamine amidotransferase
ABEKA_0066	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABEKA_0067	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABEKA_0068	COG0756	dUTP diphosphatase activity
ABEKA_0069	COG0210	DNA helicase
ABEKA_0070	COG2885	chlorophyll binding
ABEKA_0071	COG0204	Acyl-transferase
ABEKA_0073	COG0850	regulation of cytokinetic process
ABEKA_0074	COG2894	cell division
ABEKA_0077	COG0531	amino acid
ABEKA_0077	COG1674	ftsk spoiiie
ABEKA_0078	COG0492	ferredoxin-NADP+ reductase activity
ABEKA_0079	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABEKA_0081	COG0456	acetyltransferase
ABEKA_0083	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABEKA_0086	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABEKA_0089	COG1981	membrane
ABEKA_0090	COG1113	amino acid transport
ABEKA_0091	COG0251	oxidation-reduction process
ABEKA_0095	COG1652	LysM domain
ABEKA_0096	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABEKA_0097	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_0098	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABEKA_0100	COG1399	metal-binding, possibly nucleic acid-binding protein
ABEKA_0101	COG3101	peptidyl-lysine hydroxylation
ABEKA_0102	COG0009	L-threonylcarbamoyladenylate synthase
ABEKA_0105	COG3293	Transposase
ABEKA_0106	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABEKA_0107	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABEKA_0112	COG0339	signal peptide processing
ABEKA_0120	COG2193	ferroxidase activity
ABEKA_0121	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABEKA_0122	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABEKA_0124	COG1196	nuclear chromosome segregation
ABEKA_0126	COG0730	response to heat
ABEKA_0131	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABEKA_0133	COG4106	trans-aconitate 2-methyltransferase activity
ABEKA_0135	COG3327	negative regulation of DNA-templated transcription, initiation
ABEKA_0136	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ABEKA_0137	COG3293	Transposase
ABEKA_0140	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABEKA_0141	COG1024	Enoyl-CoA hydratase
ABEKA_0142	COG1024	Enoyl-CoA hydratase
ABEKA_0143	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABEKA_0144	COG2151	metal-sulfur cluster biosynthetic enzyme
ABEKA_0145	COG3396	Phenylacetate-CoA oxygenase
ABEKA_0146	COG3460	Phenylacetate-CoA oxygenase
ABEKA_0147	COG3396	Phenylacetate-CoA oxygenase
ABEKA_0148	COG1012	belongs to the aldehyde dehydrogenase family
ABEKA_0148	COG2030	dehydratase
ABEKA_0149	COG2814	Major facilitator Superfamily
ABEKA_0152	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABEKA_0154	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABEKA_0157	COG4269	membrane
ABEKA_0161	COG1968	undecaprenyl-diphosphatase activity
ABEKA_0162	COG1214	PFAM Peptidase M22, glycoprotease
ABEKA_0164	COG0494	nUDIX hydrolase
ABEKA_0174	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABEKA_0175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABEKA_0188	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABEKA_0189	COG1764	response to oxidative stress
ABEKA_0198	COG0037	tRNA processing
ABEKA_0200	COG0248	Ppx GppA phosphatase
ABEKA_0205	COG0072	phenylalanine-tRNA ligase activity
ABEKA_0211	COG1238	metal cluster binding
ABEKA_0213	COG0625	glutathione transferase activity
ABEKA_0217	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABEKA_0221	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_0224	COG4206	TonB-dependent receptor
ABEKA_0225	COG2096	Adenosyltransferase
ABEKA_0228	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABEKA_0230	COG0745	RESPONSE REGULATOR receiver
ABEKA_0231	COG2205	protein histidine kinase activity
ABEKA_0233	COG1960	acyl-CoA dehydrogenase activity
ABEKA_0234	COG1960	acyl-CoA dehydrogenase activity
ABEKA_0242	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABEKA_0253	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABEKA_0254	COG0675	Transposase, IS605 OrfB family
ABEKA_0257	COG2205	protein histidine kinase activity
ABEKA_0260	COG1660	Displays ATPase and GTPase activities
ABEKA_0263	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABEKA_0264	COG0617	tRNA 3'-terminal CCA addition
ABEKA_0265	COG3956	TIGRFAM MazG family protein
ABEKA_0266	COG0300	oxidoreductase activity
ABEKA_0269	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABEKA_0273	COG1426	Protein conserved in bacteria
ABEKA_0277	COG2975	iron-sulfur cluster assembly
ABEKA_0282	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_0283	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_0288	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_0289	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABEKA_0290	COG0440	acetolactate synthase activity
ABEKA_0291	COG0028	Belongs to the TPP enzyme family
ABEKA_0296	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABEKA_0297	COG0577	efflux transmembrane transporter activity
ABEKA_0297	COG1136	(ABC) transporter
ABEKA_0298	COG1538	Outer membrane efflux protein
ABEKA_0300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABEKA_0302	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABEKA_0303	COG1162	GTPase activity
ABEKA_0308	COG0084	hydrolase, TatD family'
ABEKA_0311	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABEKA_0314	COG0793	Belongs to the peptidase S41A family
ABEKA_0320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABEKA_0321	COG0280	phosphate acetyltransferase
ABEKA_0321	COG0857	belongs to the CobB CobQ family
ABEKA_0325	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ABEKA_0325	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ABEKA_0330	COG0740	serine-type endopeptidase activity
ABEKA_0332	COG4771	TonB-dependent receptor
ABEKA_0333	COG4774	siderophore transport
ABEKA_0335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABEKA_0336	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABEKA_0337	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABEKA_0337	COG2813	Specifically methylates the guanine in position
ABEKA_0340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABEKA_0354	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ABEKA_0357	COG4974	Belongs to the 'phage' integrase family
ABEKA_0364	COG4974	Belongs to the 'phage' integrase family
ABEKA_0370	COG4372	Transposase
ABEKA_0372	COG2963	transposase activity
ABEKA_0376	COG2963	transposase activity
ABEKA_0378	COG4372	Transposase
ABEKA_0399	COG0788	formyltetrahydrofolate deformylase activity
ABEKA_0405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABEKA_0405	COG4651	solute:proton antiporter activity
ABEKA_0409	COG0210	DNA helicase
ABEKA_0410	COG1929	Belongs to the glycerate kinase type-1 family
ABEKA_0416	COG2900	Belongs to the SlyX family
ABEKA_0417	COG0488	(ABC) transporter
ABEKA_0418	COG1560	Kdo2-lipid A biosynthetic process
ABEKA_0430	COG0473	3-isopropylmalate dehydrogenase activity
ABEKA_0433	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABEKA_0435	COG0583	DNA-binding transcription factor activity
ABEKA_0445	COG0753	catalase activity
ABEKA_0452	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABEKA_0453	COG3384	dioxygenase
ABEKA_0454	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_0457	COG4638	Rieske (2fe-2S)
ABEKA_0458	COG4638	Rieske (2fe-2S)
ABEKA_0459	COG0583	DNA-binding transcription factor activity
ABEKA_0463	COG4569	acetaldehyde dehydrogenase (acetylating) activity
ABEKA_0464	COG3971	2-oxopent-4-enoate hydratase activity
ABEKA_0465	COG0546	phosphoglycolate phosphatase activity
ABEKA_0466	COG0564	pseudouridine synthase activity
ABEKA_0467	COG1530	ribonuclease E activity
ABEKA_0468	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_0473	COG1983	PspC domain protein
ABEKA_0475	COG0471	metal ion transport
ABEKA_0480	COG0751	glycine-tRNA ligase activity
ABEKA_0484	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABEKA_0489	COG0493	'glutamate synthase
ABEKA_0491	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABEKA_0493	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABEKA_0497	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABEKA_0499	COG0644	oxidoreductase
ABEKA_0499	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ABEKA_0500	COG0425	Belongs to the sulfur carrier protein TusA family
ABEKA_0501	COG4535	Mg2 and Co2 transporter CorC
ABEKA_0506	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABEKA_0507	COG0475	glutathione-regulated potassium exporter activity
ABEKA_0507	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABEKA_0508	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABEKA_0510	COG0789	Transcriptional regulator
ABEKA_0511	COG2841	Protein conserved in bacteria
ABEKA_0512	COG1185	polyribonucleotide nucleotidyltransferase activity
ABEKA_0513	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ABEKA_0514	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABEKA_0515	COG1074	ATP-dependent DNA helicase activity
ABEKA_0516	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABEKA_0522	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABEKA_0529	COG0427	acetyl-CoA hydrolase
ABEKA_0530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABEKA_0537	COG0326	Molecular chaperone. Has ATPase activity
ABEKA_0539	COG3047	cAMP biosynthetic process
ABEKA_0540	COG2056	Na+-H+ antiporter family
ABEKA_0544	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABEKA_0545	COG0085	RNA polymerase activity
ABEKA_0546	COG0222	ribosome binding
ABEKA_0547	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ABEKA_0548	COG0081	regulation of translation
ABEKA_0553	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABEKA_0559	COG0546	phosphoglycolate phosphatase activity
ABEKA_0565	COG0824	Thioesterase
ABEKA_0569	COG0181	hydroxymethylbilane synthase activity
ABEKA_0571	COG3275	phosphorelay sensor kinase activity
ABEKA_0575	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABEKA_0580	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABEKA_0580	COG1024	Enoyl-CoA hydratase
ABEKA_0595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABEKA_0603	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABEKA_0610	COG3158	transport of potassium into the cell
ABEKA_0612	COG0582	viral genome integration into host DNA
ABEKA_0626	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ABEKA_0629	COG2814	Major facilitator Superfamily
ABEKA_0631	COG0351	phosphomethylpyrimidine kinase
ABEKA_0631	COG0352	thiamine-phosphate diphosphorylase activity
ABEKA_0631	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABEKA_0636	COG3706	GGDEF domain
ABEKA_0639	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABEKA_0641	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABEKA_0642	COG3162	membrane
ABEKA_0643	COG2205	protein histidine kinase activity
ABEKA_0643	COG0784	Response regulator, receiver
ABEKA_0646	COG0431	NADPH-dependent FMN reductase
ABEKA_0647	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABEKA_0648	COG0415	Belongs to the DNA photolyase family
ABEKA_0650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABEKA_0652	COG3152	Membrane
ABEKA_0653	COG0668	transmembrane transport
ABEKA_0654	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABEKA_0656	COG1519	Transferase
ABEKA_0657	COG1902	pentaerythritol trinitrate reductase activity
ABEKA_0662	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABEKA_0667	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABEKA_0667	COG0426	domain, Protein
ABEKA_0668	COG2119	membrane
ABEKA_0669	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABEKA_0676	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABEKA_0678	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABEKA_0682	COG0189	ligase activity
ABEKA_0685	COG2132	Multicopper oxidase
ABEKA_0689	COG1278	Cold shock
ABEKA_0690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABEKA_0691	COG0708	Exodeoxyribonuclease III
ABEKA_0697	COG3706	GGDEF domain
ABEKA_0703	COG1247	-acetyltransferase
ABEKA_0712	COG3150	esterase
ABEKA_0714	COG3385	transposase activity
ABEKA_0715	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABEKA_0716	COG2918	glutathione biosynthetic process
ABEKA_0719	COG2733	membrane
ABEKA_0727	COG0753	catalase activity
ABEKA_0729	COG3385	transposase activity
ABEKA_0736	COG0385	Bile acid
ABEKA_0737	COG1335	isochorismatase
ABEKA_0738	COG2814	Major facilitator Superfamily
ABEKA_0740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABEKA_0742	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABEKA_0743	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABEKA_0744	COG3300	MHYT domain
ABEKA_0744	COG5001	Diguanylate cyclase
ABEKA_0745	COG2983	Belongs to the UPF0260 family
ABEKA_0746	COG5487	UPF0391 membrane protein
ABEKA_0747	COG0728	peptidoglycan biosynthetic process
ABEKA_0748	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABEKA_0751	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABEKA_0753	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABEKA_0754	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABEKA_0755	COG0546	phosphoglycolate phosphatase activity
ABEKA_0756	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_0761	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ABEKA_0761	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABEKA_0762	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABEKA_0763	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABEKA_0764	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABEKA_0765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABEKA_0766	COG1116	anion transmembrane transporter activity
ABEKA_0768	COG1309	transcriptional regulator
ABEKA_0770	COG0196	riboflavin kinase activity
ABEKA_0771	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABEKA_0772	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABEKA_0773	COG1047	Peptidyl-prolyl cis-trans
ABEKA_0776	COG2133	pyrroloquinoline quinone binding
ABEKA_0783	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABEKA_0784	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABEKA_0785	COG2951	lytic endotransglycosylase activity
ABEKA_0786	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABEKA_0790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABEKA_0795	COG2388	GCN5-related N-acetyl-transferase
ABEKA_0797	COG0861	Integral membrane protein TerC family
ABEKA_0799	COG0402	S-adenosylhomocysteine deaminase activity
ABEKA_0805	COG3385	transposase activity
ABEKA_0810	COG0706	membrane insertase activity
ABEKA_0811	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABEKA_0812	COG0594	ribonuclease P activity
ABEKA_0814	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABEKA_0815	COG0592	DNA-directed DNA polymerase activity
ABEKA_0817	COG0187	DNA topoisomerase II activity
ABEKA_0819	COG1063	alcohol dehydrogenase
ABEKA_0820	COG0488	(ABC) transporter
ABEKA_0832	COG0657	acetylesterase activity
ABEKA_0834	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABEKA_0840	COG2814	Major facilitator Superfamily
ABEKA_0841	COG2814	Major facilitator Superfamily
ABEKA_0843	COG0666	response to abiotic stimulus
ABEKA_0844	COG0693	protein deglycase activity
ABEKA_0846	COG1012	belongs to the aldehyde dehydrogenase family
ABEKA_0847	COG0733	neurotransmitter:sodium symporter activity
ABEKA_0849	COG0428	transporter
ABEKA_0853	COG0675	Transposase, IS605 OrfB family
ABEKA_0854	COG0129	dihydroxy-acid dehydratase activity
ABEKA_0855	COG0675	Transposase, IS605 OrfB family
ABEKA_0860	COG2233	PERMEase
ABEKA_0862	COG1309	transcriptional regulator
ABEKA_0872	COG1064	alcohol dehydrogenase
ABEKA_0873	COG2818	Glycosylase
ABEKA_0875	COG0739	heme binding
ABEKA_0884	COG1596	polysaccharide export
ABEKA_0886	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ABEKA_0888	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABEKA_0892	COG1215	transferase activity, transferring glycosyl groups
ABEKA_0894	COG0438	transferase activity, transferring glycosyl groups
ABEKA_0897	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABEKA_0900	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABEKA_0903	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABEKA_0904	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABEKA_0913	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABEKA_0915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABEKA_0916	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABEKA_0918	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABEKA_0922	COG0281	malic enzyme
ABEKA_0925	COG0271	Belongs to the BolA IbaG family
ABEKA_0927	COG1192	Involved in chromosome partitioning
ABEKA_0930	COG0586	Pfam SNARE associated Golgi protein
ABEKA_0931	COG0519	Catalyzes the synthesis of GMP from XMP
ABEKA_0931	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABEKA_0932	COG1715	Restriction endonuclease
ABEKA_0933	COG3706	GGDEF domain
ABEKA_0934	COG3706	GGDEF domain
ABEKA_0937	COG0625	glutathione transferase activity
ABEKA_0942	COG0534	Mate efflux family protein
ABEKA_0943	COG0436	Aminotransferase
ABEKA_0953	COG2837	iron assimilation
ABEKA_0955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABEKA_0956	COG1121	(ABC) transporter
ABEKA_0966	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABEKA_0969	COG1012	belongs to the aldehyde dehydrogenase family
ABEKA_0972	COG0386	Belongs to the glutathione peroxidase family
ABEKA_0973	COG0697	spore germination
ABEKA_0975	COG0758	DNA mediated transformation
ABEKA_0985	COG2814	Major facilitator Superfamily
ABEKA_0989	COG0477	Major facilitator Superfamily
ABEKA_0990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABEKA_0998	COG1253	flavin adenine dinucleotide binding
ABEKA_1000	COG2860	membrane
ABEKA_1001	COG0477	Major facilitator Superfamily
ABEKA_1003	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_1006	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABEKA_1009	COG0606	chelatase, subunit chli
ABEKA_1019	COG2433	Pfam Transposase IS66
ABEKA_1022	COG4372	Transposase
ABEKA_1023	COG3335	DDE superfamily endonuclease
ABEKA_1032	COG0438	transferase activity, transferring glycosyl groups
ABEKA_1032	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABEKA_1039	COG0347	Belongs to the P(II) protein family
ABEKA_1040	COG0004	ammonium transporteR
ABEKA_1042	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABEKA_1042	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABEKA_1045	COG0586	Pfam SNARE associated Golgi protein
ABEKA_1049	COG0795	lipopolysaccharide-transporting ATPase activity
ABEKA_1050	COG0795	lipopolysaccharide-transporting ATPase activity
ABEKA_1051	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABEKA_1052	COG0793	Belongs to the peptidase S41A family
ABEKA_1052	COG3409	Peptidoglycan-binding domain 1 protein
ABEKA_1054	COG4191	Histidine kinase
ABEKA_1059	COG2197	response regulator
ABEKA_1060	COG1686	Belongs to the peptidase S11 family
ABEKA_1061	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABEKA_1063	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABEKA_1064	COG4974	Belongs to the 'phage' integrase family
ABEKA_1069	COG0772	Belongs to the SEDS family
ABEKA_1071	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABEKA_1072	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABEKA_1074	COG0494	nUDIX hydrolase
ABEKA_1078	COG1538	Outer membrane efflux protein
ABEKA_1080	COG1132	(ABC) transporter
ABEKA_1082	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABEKA_1092	COG0497	DNA recombination
ABEKA_1094	COG3123	guanosine phosphorylase activity
ABEKA_1095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABEKA_1097	COG0237	dephospho-CoA kinase activity
ABEKA_1101	COG0149	triose-phosphate isomerase activity
ABEKA_1108	COG0779	Required for maturation of 30S ribosomal subunits
ABEKA_1109	COG0195	Participates in both transcription termination and antitermination
ABEKA_1111	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABEKA_1113	COG3385	transposase activity
ABEKA_1114	COG1320	monovalent cation:proton antiporter activity
ABEKA_1115	COG2212	antiporter activity
ABEKA_1116	COG1863	multisubunit Na H antiporter MnhE subunit
ABEKA_1117	COG0651	ATP synthesis coupled electron transport
ABEKA_1118	COG1006	Multisubunit Na H antiporter MnhC subunit
ABEKA_1119	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABEKA_1119	COG2111	Na H antiporter
ABEKA_1122	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABEKA_1123	COG4221	oxidoreductase activity
ABEKA_1124	COG2873	o-acetylhomoserine
ABEKA_1125	COG0488	(ABC) transporter
ABEKA_1129	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABEKA_1132	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABEKA_1136	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABEKA_1137	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABEKA_1138	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABEKA_1139	COG2226	methyltransferase
ABEKA_1152	COG3307	-O-antigen
ABEKA_1157	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABEKA_1158	COG1758	RNA polymerase activity
ABEKA_1159	COG0194	GDP metabolic process
ABEKA_1164	COG0228	four-way junction DNA binding
ABEKA_1165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABEKA_1167	COG0335	large ribosomal subunit rRNA binding
ABEKA_1168	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABEKA_1170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABEKA_1171	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ABEKA_1172	COG5380	lipid catabolic process
ABEKA_1173	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABEKA_1176	COG0675	Transposase, IS605 OrfB family
ABEKA_1177	COG0730	response to heat
ABEKA_1183	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABEKA_1185	COG0277	FAD linked oxidase domain protein
ABEKA_1189	COG2814	Major facilitator Superfamily
ABEKA_1190	COG1289	transmembrane transporter activity
ABEKA_1192	COG0628	permease
ABEKA_1199	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABEKA_1200	COG0254	rRNA binding
ABEKA_1201	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABEKA_1203	COG0534	Mate efflux family protein
ABEKA_1205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABEKA_1207	COG1278	Cold shock
ABEKA_1208	COG1960	acyl-CoA dehydrogenase activity
ABEKA_1214	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABEKA_1218	COG0513	Belongs to the DEAD box helicase family
ABEKA_1219	COG1127	ABC transporter
ABEKA_1220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABEKA_1221	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABEKA_1225	COG0598	Magnesium transport protein CorA
ABEKA_1227	COG0494	nUDIX hydrolase
ABEKA_1228	COG1040	competence protein
ABEKA_1229	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABEKA_1231	COG2937	Belongs to the GPAT DAPAT family
ABEKA_1232	COG1946	Acyl-CoA thioesterase
ABEKA_1233	COG1301	dicarboxylic acid transport
ABEKA_1235	COG1959	2 iron, 2 sulfur cluster binding
ABEKA_1236	COG1017	nitric oxide dioxygenase activity
ABEKA_1236	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABEKA_1237	COG0433	COG0433 Predicted ATPase
ABEKA_1238	COG0626	cystathionine gamma-synthase activity
ABEKA_1242	COG0088	Forms part of the polypeptide exit tunnel
ABEKA_1243	COG0089	rRNA binding
ABEKA_1245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABEKA_1255	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABEKA_1256	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABEKA_1258	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABEKA_1263	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABEKA_1265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABEKA_1266	COG0202	RNA polymerase activity
ABEKA_1267	COG0203	ribosomal protein L17
ABEKA_1268	COG2072	flavoprotein involved in K transport
ABEKA_1269	COG1960	acyl-CoA dehydrogenase activity
ABEKA_1270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABEKA_1278	COG0697	spore germination
ABEKA_1280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ABEKA_1281	COG0339	signal peptide processing
ABEKA_1283	COG0557	exoribonuclease II activity
ABEKA_1291	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABEKA_1296	COG1295	ribonuclease BN
ABEKA_1313	COG1702	phosphate starvation-inducible protein PhoH
ABEKA_1314	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABEKA_1315	COG0739	heme binding
ABEKA_1315	COG0741	lytic transglycosylase activity
ABEKA_1315	COG1196	nuclear chromosome segregation
ABEKA_1323	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABEKA_1324	COG1183	phosphatidylcholine synthase activity
ABEKA_1337	COG1607	acyl-coa hydrolase
ABEKA_1344	COG2350	Protein conserved in bacteria
ABEKA_1347	COG3781	membrane
ABEKA_1348	COG2003	Belongs to the UPF0758 family
ABEKA_1349	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABEKA_1352	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABEKA_1354	COG2814	Major facilitator Superfamily
ABEKA_1360	COG3622	Belongs to the hyi family
ABEKA_1361	COG2084	Dehydrogenase
ABEKA_1365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABEKA_1368	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABEKA_1370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABEKA_1372	COG1862	Preprotein translocase
ABEKA_1375	COG1704	LemA family
ABEKA_1377	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABEKA_1389	COG0285	dihydrofolate synthase activity
ABEKA_1392	COG0450	alkyl hydroperoxide reductase
ABEKA_1393	COG0653	protein targeting
ABEKA_1395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABEKA_1396	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABEKA_1408	COG2969	positive regulation of protein catabolic process
ABEKA_1409	COG0625	glutathione transferase activity
ABEKA_1411	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABEKA_1412	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABEKA_1413	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABEKA_1414	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABEKA_1415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABEKA_1418	COG3293	Transposase
ABEKA_1423	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABEKA_1426	COG3385	transposase activity
ABEKA_1427	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABEKA_1428	COG1408	metallophosphoesterase
ABEKA_1430	COG0477	Major facilitator Superfamily
ABEKA_1431	COG1272	protein, Hemolysin III
ABEKA_1436	COG1024	Enoyl-CoA hydratase
ABEKA_1436	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABEKA_1437	COG0183	Belongs to the thiolase family
ABEKA_1438	COG2207	Transcriptional regulator
ABEKA_1439	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABEKA_1440	COG3293	Transposase
ABEKA_1441	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABEKA_1448	COG0183	Belongs to the thiolase family
ABEKA_1452	COG0833	amino acid
ABEKA_1454	COG2233	PERMEase
ABEKA_1455	COG1217	gtp-binding protein TYPA
ABEKA_1460	COG1902	pentaerythritol trinitrate reductase activity
ABEKA_1464	COG0354	folic acid binding
ABEKA_1465	COG2132	Multicopper oxidase
ABEKA_1474	COG0564	pseudouridine synthase activity
ABEKA_1478	COG2824	Alkylphosphonate utilization operon protein PhnA
ABEKA_1482	COG0628	permease
ABEKA_1485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABEKA_1485	COG0352	thiamine-phosphate diphosphorylase activity
ABEKA_1485	COG0351	phosphomethylpyrimidine kinase
ABEKA_1488	COG3152	Membrane
ABEKA_1491	COG4772	TonB-dependent receptor
ABEKA_1499	COG2223	nitrite transmembrane transporter activity
ABEKA_1503	COG2801	Transposase and inactivated derivatives
ABEKA_1512	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABEKA_1525	COG4372	Transposase
ABEKA_1526	COG2433	Pfam Transposase IS66
ABEKA_1540	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ABEKA_1548	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABEKA_1548	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABEKA_1549	COG0745	RESPONSE REGULATOR receiver
ABEKA_1550	COG2205	protein histidine kinase activity
ABEKA_1552	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABEKA_1556	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ABEKA_1559	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABEKA_1561	COG0713	ATP synthesis coupled electron transport
ABEKA_1562	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABEKA_1563	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABEKA_1570	COG1278	Cold shock
ABEKA_1571	COG0583	DNA-binding transcription factor activity
ABEKA_1575	COG0531	amino acid
ABEKA_1576	COG4303	Ethanolamine ammonia lyase large subunit
ABEKA_1577	COG4302	ethanolamine ammonia-lyase activity
ABEKA_1579	COG0668	transmembrane transport
ABEKA_1582	COG2081	HI0933 family
ABEKA_1584	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ABEKA_1587	COG0004	ammonium transporteR
ABEKA_1588	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABEKA_1591	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABEKA_1591	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABEKA_1595	COG0489	protein tyrosine kinase activity
ABEKA_1610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABEKA_1622	COG2832	Protein of unknown function (DUF454)
ABEKA_1634	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABEKA_1636	COG1289	transmembrane transporter activity
ABEKA_1637	COG2814	Major facilitator Superfamily
ABEKA_1641	COG0786	glutamate:sodium symporter activity
ABEKA_1642	COG1115	amino acid carrier protein
ABEKA_1643	COG2059	Chromate
ABEKA_1645	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABEKA_1650	COG1607	acyl-coa hydrolase
ABEKA_1652	COG2814	Major facilitator Superfamily
ABEKA_1658	COG0523	cobalamin synthesis protein
ABEKA_1659	COG4681	YaeQ
ABEKA_1663	COG5001	Diguanylate cyclase
ABEKA_1663	COG2203	Gaf domain
ABEKA_1663	COG3706	GGDEF domain
ABEKA_1663	COG4251	negative regulation of phosphorylation
ABEKA_1669	COG0393	Putative heavy-metal-binding
ABEKA_1670	COG0393	Putative heavy-metal-binding
ABEKA_1673	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABEKA_1674	COG0671	phosphoesterase, PA-phosphatase related
ABEKA_1677	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABEKA_1679	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABEKA_1683	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABEKA_1684	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABEKA_1684	COG1648	precorrin-2 dehydrogenase activity
ABEKA_1685	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABEKA_1687	COG0531	amino acid
ABEKA_1690	COG0321	lipoyl(octanoyl) transferase activity
ABEKA_1691	COG2921	Belongs to the UPF0250 family
ABEKA_1697	COG0586	Pfam SNARE associated Golgi protein
ABEKA_1708	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABEKA_1709	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABEKA_1715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABEKA_1717	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ABEKA_1718	COG0358	DNA primase activity
ABEKA_1720	COG0564	pseudouridine synthase activity
ABEKA_1725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABEKA_1729	COG0251	oxidation-reduction process
ABEKA_1730	COG1309	transcriptional regulator
ABEKA_1732	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABEKA_1733	COG0505	Belongs to the CarA family
ABEKA_1739	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABEKA_1741	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABEKA_1749	COG1253	flavin adenine dinucleotide binding
ABEKA_1753	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABEKA_1754	COG2239	Acts as a magnesium transporter
ABEKA_1756	COG0501	Belongs to the peptidase M48B family
ABEKA_1757	COG0739	heme binding
ABEKA_1757	COG0741	lytic transglycosylase activity
ABEKA_1757	COG1196	nuclear chromosome segregation
ABEKA_1758	COG0037	tRNA processing
ABEKA_1761	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABEKA_1768	COG2433	Pfam Transposase IS66
ABEKA_1770	COG0789	Transcriptional regulator
ABEKA_1772	COG1902	pentaerythritol trinitrate reductase activity
ABEKA_1774	COG3268	Saccharopine dehydrogenase
ABEKA_1775	COG1012	belongs to the aldehyde dehydrogenase family
ABEKA_1777	COG0657	acetylesterase activity
ABEKA_1778	COG1846	Transcriptional regulator
ABEKA_1779	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABEKA_1783	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABEKA_1787	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ABEKA_1790	COG1716	ATPase activity
ABEKA_1790	COG5001	Diguanylate cyclase
ABEKA_1791	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABEKA_1792	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABEKA_1793	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABEKA_1801	COG1115	amino acid carrier protein
ABEKA_1802	COG1113	amino acid transport
ABEKA_1804	COG0019	diaminopimelate decarboxylase activity
ABEKA_1807	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABEKA_1809	COG1522	sequence-specific DNA binding
ABEKA_1810	COG1280	lysine exporter protein (LysE YggA)
ABEKA_1818	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABEKA_1824	COG1671	Belongs to the UPF0178 family
ABEKA_1828	COG1136	(ABC) transporter
ABEKA_1829	COG2333	competence protein COMEC
ABEKA_1829	COG0658	competence protein
ABEKA_1832	COG2267	carboxylic ester hydrolase activity
ABEKA_1833	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABEKA_1834	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABEKA_1835	COG0628	permease
ABEKA_1841	COG3293	Transposase
ABEKA_1848	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABEKA_1853	COG0823	Involved in the tonB-independent uptake of proteins
ABEKA_1857	COG0824	Thioesterase
ABEKA_1858	COG1473	amidohydrolase
ABEKA_1861	COG2255	four-way junction helicase activity
ABEKA_1868	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABEKA_1868	COG0047	phosphoribosylformylglycinamidine synthase activity
ABEKA_1872	COG0583	DNA-binding transcription factor activity
ABEKA_1875	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ABEKA_1877	COG0778	Nitroreductase
ABEKA_1879	COG1056	cytidyltransferase-related domain
ABEKA_1879	COG1051	belongs to the nudix hydrolase family
ABEKA_1880	COG0583	DNA-binding transcription factor activity
ABEKA_1884	COG2353	YceI-like domain
ABEKA_1885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABEKA_1887	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABEKA_1888	COG0602	queuosine metabolic process
ABEKA_1892	COG0583	DNA-binding transcription factor activity
ABEKA_1893	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABEKA_1894	COG4208	sulfate ABC transporter
ABEKA_1897	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABEKA_1898	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABEKA_1900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABEKA_1904	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABEKA_1909	COG0571	ribonuclease III activity
ABEKA_1910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABEKA_1913	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABEKA_1918	COG0534	Mate efflux family protein
ABEKA_1919	COG0436	Aminotransferase
ABEKA_1921	COG0052	Belongs to the universal ribosomal protein uS2 family
ABEKA_1928	COG2951	lytic endotransglycosylase activity
ABEKA_1931	COG0842	Transport permease protein
ABEKA_1932	COG1131	(ABC) transporter
ABEKA_1934	COG3706	GGDEF domain
ABEKA_1945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABEKA_1949	COG3634	alkyl hydroperoxide reductase activity
ABEKA_1951	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABEKA_1952	COG0826	peptidase U32
ABEKA_1958	COG1720	tRNA m6t6A37 methyltransferase activity
ABEKA_1960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABEKA_1963	COG0642	Histidine kinase
ABEKA_1965	COG0494	nUDIX hydrolase
ABEKA_1967	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABEKA_1968	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABEKA_1969	COG3139	Protein of unknown function (DUF1315)
ABEKA_1971	COG1301	dicarboxylic acid transport
ABEKA_1972	COG1960	acyl-CoA dehydrogenase activity
ABEKA_1973	COG0693	protein deglycase activity
ABEKA_1975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABEKA_1976	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABEKA_1984	COG2252	PERMEase
ABEKA_1985	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABEKA_1992	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABEKA_1994	COG0527	aspartate kinase activity
ABEKA_1995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABEKA_1996	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABEKA_1999	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABEKA_2003	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABEKA_2007	COG1252	NADH dehydrogenase
ABEKA_2008	COG1686	Belongs to the peptidase S11 family
ABEKA_2013	COG2351	hydroxyisourate hydrolase activity
ABEKA_2019	COG0436	Aminotransferase
ABEKA_2020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABEKA_2021	COG0386	Belongs to the glutathione peroxidase family
ABEKA_2023	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ABEKA_2027	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABEKA_2030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABEKA_2031	COG0012	GTP binding
ABEKA_2036	COG0204	Acyl-transferase
ABEKA_2048	COG0830	nickel cation binding
ABEKA_2051	COG0829	nickel cation binding
ABEKA_2052	COG0831	urea catabolic process
ABEKA_2055	COG0804	urea catabolic process
ABEKA_2060	COG2351	hydroxyisourate hydrolase activity
ABEKA_2061	COG2233	PERMEase
ABEKA_2064	COG4266	Belongs to the allantoicase family
ABEKA_2065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABEKA_2066	COG0583	DNA-binding transcription factor activity
ABEKA_2071	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ABEKA_2075	COG1401	restriction endodeoxyribonuclease activity
ABEKA_2075	COG1401	restriction endodeoxyribonuclease activity
ABEKA_2077	COG0210	DNA helicase
ABEKA_2078	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABEKA_2080	COG4372	Transposase
ABEKA_2093	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABEKA_2093	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABEKA_2094	COG1254	Belongs to the acylphosphatase family
ABEKA_2099	COG3634	alkyl hydroperoxide reductase activity
ABEKA_2105	COG1643	Atp-dependent helicase
ABEKA_2109	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABEKA_2116	COG0802	atpase or kinase
ABEKA_2117	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABEKA_2119	COG1923	regulation of RNA biosynthetic process
ABEKA_2120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABEKA_2123	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABEKA_2125	COG1192	Involved in chromosome partitioning
ABEKA_2126	COG1475	DNA binding
ABEKA_2127	COG0811	peptide transport
ABEKA_2129	COG1132	(ABC) transporter
ABEKA_2130	COG1663	tetraacyldisaccharide 4'-kinase activity
ABEKA_2134	COG0084	hydrolase, TatD family'
ABEKA_2135	COG1309	transcriptional regulator
ABEKA_2141	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABEKA_2147	COG0776	regulation of translation
ABEKA_2150	COG2431	L-lysine efflux transmembrane transporter activity
ABEKA_2154	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABEKA_2155	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABEKA_2159	COG1253	flavin adenine dinucleotide binding
ABEKA_2161	COG3293	Transposase
ABEKA_2167	COG0308	aminopeptidase N
ABEKA_2169	COG0589	response to stress
ABEKA_2170	COG0589	response to stress
ABEKA_2173	COG3135	benzoate transporter
ABEKA_2175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABEKA_2176	COG0583	DNA-binding transcription factor activity
ABEKA_2179	COG3385	transposase activity
ABEKA_2180	COG0183	Belongs to the thiolase family
ABEKA_2181	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_2183	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABEKA_2186	COG0824	Thioesterase
ABEKA_2187	COG1454	alcohol dehydrogenase
ABEKA_2188	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABEKA_2192	COG0069	glutamate synthase activity
ABEKA_2194	COG2308	Evidence 4 Homologs of previously reported genes of
ABEKA_2196	COG1305	Transglutaminase-like
ABEKA_2199	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABEKA_2200	COG0305	Participates in initiation and elongation during chromosome replication
ABEKA_2203	COG0360	Binds together with S18 to 16S ribosomal RNA
ABEKA_2205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABEKA_2206	COG1845	cytochrome c oxidase, subunit III
ABEKA_2207	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABEKA_2208	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABEKA_2213	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABEKA_2216	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABEKA_2217	COG2890	protein-(glutamine-N5) methyltransferase activity
ABEKA_2221	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2222	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABEKA_2225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABEKA_2233	COG0477	Major facilitator Superfamily
ABEKA_2234	COG0729	surface antigen
ABEKA_2243	COG1570	exodeoxyribonuclease VII activity
ABEKA_2256	COG1114	Component of the transport system for branched-chain amino acids
ABEKA_2258	COG0583	DNA-binding transcription factor activity
ABEKA_2259	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABEKA_2262	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABEKA_2262	COG1902	pentaerythritol trinitrate reductase activity
ABEKA_2269	COG0148	phosphopyruvate hydratase activity
ABEKA_2272	COG3293	Transposase
ABEKA_2273	COG0772	Belongs to the SEDS family
ABEKA_2276	COG4890	Cyd operon protein YbgT
ABEKA_2277	COG1294	oxidase, subunit
ABEKA_2281	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_2283	COG0537	adenosine 5'-monophosphoramidase activity
ABEKA_2292	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABEKA_2296	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABEKA_2298	COG0133	tryptophan synthase activity
ABEKA_2299	COG0517	IMP dehydrogenase activity
ABEKA_2304	COG0612	Peptidase, M16
ABEKA_2306	COG0552	protein localization to endoplasmic reticulum
ABEKA_2320	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2333	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABEKA_2334	COG0730	response to heat
ABEKA_2335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABEKA_2336	COG2207	Transcriptional regulator
ABEKA_2337	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABEKA_2338	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2339	COG2169	Transcriptional regulator
ABEKA_2342	COG1271	oxidase subunit
ABEKA_2343	COG1294	oxidase, subunit
ABEKA_2345	COG1525	nuclease
ABEKA_2356	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABEKA_2359	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABEKA_2361	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABEKA_2363	COG0509	glycine decarboxylation via glycine cleavage system
ABEKA_2365	COG1132	(ABC) transporter
ABEKA_2366	COG0668	transmembrane transport
ABEKA_2367	COG3122	Protein conserved in bacteria
ABEKA_2371	COG0640	Transcriptional regulator
ABEKA_2372	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABEKA_2374	COG0789	Transcriptional regulator
ABEKA_2378	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2379	COG0183	Belongs to the thiolase family
ABEKA_2383	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABEKA_2384	COG0183	Belongs to the thiolase family
ABEKA_2385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABEKA_2386	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABEKA_2387	COG3135	benzoate transporter
ABEKA_2388	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_2389	COG0543	2 iron, 2 sulfur cluster binding
ABEKA_2389	COG0633	Ferredoxin
ABEKA_2390	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ABEKA_2391	COG4638	Rieske (2fe-2S)
ABEKA_2393	COG4829	muconolactone delta-isomerase
ABEKA_2394	COG4948	Mandelate Racemase Muconate Lactonizing
ABEKA_2395	COG0583	DNA-binding transcription factor activity
ABEKA_2396	COG2814	Major facilitator Superfamily
ABEKA_2398	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABEKA_2400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABEKA_2401	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_2402	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABEKA_2402	COG1017	nitric oxide dioxygenase activity
ABEKA_2405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABEKA_2409	COG0439	Biotin carboxylase
ABEKA_2410	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_2415	COG0864	Transcriptional regulator
ABEKA_2417	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABEKA_2422	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABEKA_2423	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABEKA_2423	COG1116	anion transmembrane transporter activity
ABEKA_2425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABEKA_2426	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABEKA_2427	COG0243	molybdopterin cofactor binding
ABEKA_2429	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABEKA_2431	COG0314	molybdopterin synthase activity
ABEKA_2432	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABEKA_2432	COG0315	cyclic pyranopterin monophosphate synthase activity
ABEKA_2433	COG0303	'Molybdopterin
ABEKA_2434	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABEKA_2435	COG4149	molybdate abc transporter
ABEKA_2436	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABEKA_2437	COG2223	nitrite transmembrane transporter activity
ABEKA_2438	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ABEKA_2439	COG2116	formate transmembrane transporter activity
ABEKA_2440	COG0515	serine threonine protein kinase
ABEKA_2443	COG0583	DNA-binding transcription factor activity
ABEKA_2446	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABEKA_2447	COG1309	transcriptional regulator
ABEKA_2452	COG1944	ATP diphosphatase activity
ABEKA_2453	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ABEKA_2453	COG0644	oxidoreductase
ABEKA_2455	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2456	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2457	COG2814	Major facilitator Superfamily
ABEKA_2458	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABEKA_2459	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABEKA_2460	COG5001	Diguanylate cyclase
ABEKA_2461	COG2814	Major facilitator Superfamily
ABEKA_2463	COG2814	Major facilitator Superfamily
ABEKA_2464	COG1024	Enoyl-CoA hydratase
ABEKA_2465	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABEKA_2466	COG0183	Belongs to the thiolase family
ABEKA_2468	COG0235	Class ii aldolase
ABEKA_2470	COG1024	Enoyl-CoA hydratase
ABEKA_2472	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2475	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_2476	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABEKA_2477	COG2814	Major facilitator Superfamily
ABEKA_2487	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABEKA_2488	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2489	COG1024	Enoyl-CoA hydratase
ABEKA_2492	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_2495	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABEKA_2496	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABEKA_2502	COG2194	sulfuric ester hydrolase activity
ABEKA_2503	COG0745	RESPONSE REGULATOR receiver
ABEKA_2504	COG0642	Histidine kinase
ABEKA_2510	COG0300	oxidoreductase activity
ABEKA_2511	COG2801	Transposase and inactivated derivatives
ABEKA_2514	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_2516	COG0596	Alpha beta hydrolase
ABEKA_2517	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_2524	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABEKA_2531	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABEKA_2532	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ABEKA_2534	COG0439	Biotin carboxylase
ABEKA_2538	COG2814	Major facilitator Superfamily
ABEKA_2539	COG0753	catalase activity
ABEKA_2552	COG0372	Belongs to the citrate synthase family
ABEKA_2559	COG0542	response to heat
ABEKA_2560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABEKA_2564	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABEKA_2565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABEKA_2572	COG0569	domain protein
ABEKA_2573	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABEKA_2577	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABEKA_2579	COG1585	Membrane protein implicated in regulation of membrane protease activity
ABEKA_2583	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABEKA_2584	COG0776	regulation of translation
ABEKA_2589	COG0822	iron-sulfur transferase activity
ABEKA_2590	COG0316	Belongs to the HesB IscA family
ABEKA_2596	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABEKA_2598	COG1027	Aspartate ammonia-lyase
ABEKA_2599	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABEKA_2605	COG3781	membrane
ABEKA_2615	COG0778	Nitroreductase
ABEKA_2616	COG0697	spore germination
ABEKA_2621	COG0424	maF-like protein
ABEKA_2622	COG2850	peptidyl-arginine hydroxylation
ABEKA_2623	COG4585	Histidine kinase
ABEKA_2624	COG2197	response regulator
ABEKA_2626	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABEKA_2627	COG0702	epimerase
ABEKA_2628	COG0268	Binds directly to 16S ribosomal RNA
ABEKA_2632	COG1011	Hydrolase
ABEKA_2633	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABEKA_2634	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABEKA_2635	COG2137	regulation of response to DNA damage stimulus
ABEKA_2637	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABEKA_2639	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABEKA_2641	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABEKA_2644	COG0575	Belongs to the CDS family
ABEKA_2645	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABEKA_2649	COG3852	Histidine kinase
ABEKA_2652	COG2814	Major facilitator Superfamily
ABEKA_2653	COG2814	Major facilitator Superfamily
ABEKA_2662	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ABEKA_2663	COG0138	bifunctional purine biosynthesis protein purh
ABEKA_2664	COG0151	Belongs to the GarS family
ABEKA_2670	COG1464	Belongs to the NlpA lipoprotein family
ABEKA_2671	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABEKA_2672	COG2011	ABC-type metal ion transport system permease component
ABEKA_2680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABEKA_2682	COG4122	O-methyltransferase activity
ABEKA_2689	COG1137	ATPase activity
ABEKA_2690	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ABEKA_2692	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABEKA_2693	COG0517	IMP dehydrogenase activity
ABEKA_2693	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABEKA_2699	COG0625	glutathione transferase activity
ABEKA_2704	COG0505	Belongs to the CarA family
ABEKA_2708	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABEKA_2711	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABEKA_2716	COG2391	methyltransferase activity
ABEKA_2727	COG1309	transcriptional regulator
ABEKA_2737	COG0352	thiamine-phosphate diphosphorylase activity
ABEKA_2740	COG3025	triphosphatase activity
ABEKA_2746	COG0612	Peptidase, M16
ABEKA_2766	COG2203	Gaf domain
ABEKA_2766	COG2199	diguanylate cyclase activity
ABEKA_2771	COG4783	chaperone-mediated protein folding
ABEKA_2774	COG0501	Belongs to the peptidase M48B family
ABEKA_2777	COG0167	dihydroorotate dehydrogenase activity
ABEKA_2782	COG0778	Nitroreductase
ABEKA_2784	COG0513	Belongs to the DEAD box helicase family
ABEKA_2785	COG1278	Cold shock
ABEKA_2789	COG2363	Small membrane protein
ABEKA_2792	COG0625	glutathione transferase activity
ABEKA_2793	COG0659	secondary active sulfate transmembrane transporter activity
ABEKA_2794	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABEKA_2798	COG0318	PFAM AMP-dependent synthetase and ligase
ABEKA_2799	COG1309	transcriptional regulator
ABEKA_2800	COG1960	acyl-CoA dehydrogenase activity
ABEKA_2801	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABEKA_2802	COG1024	Enoyl-CoA hydratase
ABEKA_2803	COG4770	biotin carboxylase activity
ABEKA_2806	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABEKA_2807	COG2031	fatty acid transporter
ABEKA_2810	COG0540	Belongs to the ATCase OTCase family
ABEKA_2816	COG0667	Aldo Keto reductase
ABEKA_2818	COG1765	OsmC-like protein
ABEKA_2819	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABEKA_2826	COG0640	Transcriptional regulator
ABEKA_2829	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABEKA_2830	COG4232	protein-disulfide reductase activity
ABEKA_2831	COG0745	RESPONSE REGULATOR receiver
ABEKA_2832	COG0642	Histidine kinase
ABEKA_2833	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABEKA_2834	COG2072	flavoprotein involved in K transport
ABEKA_2835	COG0431	NADPH-dependent FMN reductase
ABEKA_2836	COG0798	PFAM Bile acid sodium symporter
ABEKA_2838	COG0640	Transcriptional regulator
ABEKA_2841	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_2843	COG2199	diguanylate cyclase activity
ABEKA_2843	COG2203	Gaf domain
ABEKA_2851	COG0714	Associated with various cellular activities
ABEKA_2852	COG2879	small protein
ABEKA_2853	COG1966	Carbon starvation protein
ABEKA_2854	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABEKA_2855	COG1509	lysine 2,3-aminomutase activity
ABEKA_2858	COG0254	rRNA binding
ABEKA_2862	COG1067	ATP-dependent peptidase activity
ABEKA_2863	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABEKA_2864	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABEKA_2865	COG0583	DNA-binding transcription factor activity
ABEKA_2867	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABEKA_2870	COG1686	Belongs to the peptidase S11 family
ABEKA_2871	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABEKA_2876	COG0482	sulfurtransferase activity
ABEKA_2882	COG0616	signal peptide processing
ABEKA_2883	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABEKA_2885	COG0573	inorganic phosphate transmembrane transporter activity
ABEKA_2886	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABEKA_2887	COG0076	glutamate decarboxylase activity
ABEKA_2888	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABEKA_2890	COG0671	phosphoesterase, PA-phosphatase related
ABEKA_2891	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABEKA_2894	COG3293	Transposase
ABEKA_2896	COG1733	regulation of RNA biosynthetic process
ABEKA_2902	COG0556	nucleotide-excision repair
ABEKA_2909	COG2175	clavaminate synthase activity
ABEKA_2911	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABEKA_2912	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABEKA_2915	COG2084	Dehydrogenase
ABEKA_2916	COG2233	PERMEase
ABEKA_2917	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABEKA_2918	COG0251	oxidation-reduction process
ABEKA_2919	COG1335	isochorismatase
ABEKA_2920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABEKA_2921	COG0596	Alpha beta hydrolase
ABEKA_2923	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABEKA_2924	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABEKA_2925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABEKA_2933	COG3539	Fimbrial protein
ABEKA_2934	COG3293	Transposase
ABEKA_2944	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ABEKA_2947	COG0174	glutamine synthetase
ABEKA_2993	COG0512	Glutamine amidotransferase of anthranilate synthase
ABEKA_2994	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABEKA_2997	COG0302	gtp cyclohydrolase
ABEKA_3001	COG3706	GGDEF domain
ABEKA_3006	COG3739	integral membrane protein
ABEKA_3009	COG1741	Belongs to the pirin family
ABEKA_3013	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABEKA_3013	COG1902	pentaerythritol trinitrate reductase activity
ABEKA_3016	COG4251	negative regulation of phosphorylation
ABEKA_3016	COG5001	Diguanylate cyclase
ABEKA_3016	COG2203	Gaf domain
ABEKA_3016	COG3706	GGDEF domain
ABEKA_3017	COG0418	dihydroorotase activity
ABEKA_3023	COG0833	amino acid
ABEKA_3032	COG4239	(ABC) transporter, permease
ABEKA_3033	COG4174	ABC transporter (Permease)
ABEKA_3034	COG4166	transmembrane transport
ABEKA_3035	COG1388	LysM domain
ABEKA_3035	COG0741	lytic transglycosylase activity
ABEKA_3035	COG1388	LysM domain
ABEKA_3035	COG0741	lytic transglycosylase activity
ABEKA_3039	COG0657	acetylesterase activity
ABEKA_3042	COG3107	peptidoglycan biosynthetic process
ABEKA_3045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABEKA_3046	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABEKA_3048	COG2155	Conserved Protein
ABEKA_3049	COG0006	proline dipeptidase activity
ABEKA_3055	COG1802	Transcriptional regulator
ABEKA_3059	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABEKA_3061	COG3385	transposase activity
ABEKA_3062	COG2234	aminopeptidase activity
ABEKA_3064	COG3384	dioxygenase
ABEKA_3066	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABEKA_3067	COG2878	Part of a membrane complex involved in electron transport
ABEKA_3068	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABEKA_3073	COG0768	penicillin binding
ABEKA_3074	COG0742	ribosomal rna small subunit methyltransferase
ABEKA_3088	COG1597	lipid kinase activity
ABEKA_3092	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABEKA_3101	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABEKA_3101	COG0604	alcohol dehydrogenase
ABEKA_3101	COG4221	oxidoreductase activity
ABEKA_3101	COG3321	synthase
ABEKA_3102	COG3118	belongs to the thioredoxin family
ABEKA_3108	COG2268	Band 7 protein
ABEKA_3111	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABEKA_3115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABEKA_3116	COG1053	succinate dehydrogenase
ABEKA_3117	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABEKA_3125	COG0589	response to stress
ABEKA_3129	COG2321	neutral zinc metallopeptidase
ABEKA_3130	COG2354	Protein conserved in bacteria
ABEKA_3134	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABEKA_3135	COG1773	rubredoxin
ABEKA_3136	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABEKA_3137	COG2267	carboxylic ester hydrolase activity
ABEKA_3138	COG0583	DNA-binding transcription factor activity
ABEKA_3142	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABEKA_3144	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABEKA_3145	COG4181	ATPase activity
ABEKA_3150	COG4771	TonB-dependent receptor
ABEKA_3154	COG0306	phosphate transporter
ABEKA_3162	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_3163	COG2066	Belongs to the glutaminase family
ABEKA_3167	COG1028	Short-chain dehydrogenase reductase Sdr
ABEKA_3169	COG0525	valine-tRNA ligase activity
ABEKA_3171	COG2852	Protein conserved in bacteria
ABEKA_3175	COG2323	membrane
ABEKA_3176	COG0546	phosphoglycolate phosphatase activity
ABEKA_3180	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABEKA_3183	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABEKA_3184	COG0142	geranyltranstransferase activity
ABEKA_3185	COG2828	Protein conserved in bacteria
ABEKA_3186	COG1113	amino acid transport
ABEKA_3192	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABEKA_3195	COG0424	maF-like protein
ABEKA_3196	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ABEKA_3197	COG1792	Involved in formation and maintenance of cell shape
ABEKA_3198	COG1077	Cell shape determining protein MreB Mrl
ABEKA_3199	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABEKA_3201	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABEKA_3210	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ABEKA_3215	COG2200	EAL domain
ABEKA_3230	COG2433	Pfam Transposase IS66
ABEKA_3232	COG4372	Transposase
ABEKA_3235	COG2433	Pfam Transposase IS66
ABEKA_3241	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ABEKA_3253	COG4372	Transposase
ABEKA_3257	COG3293	Transposase
ABEKA_3261	COG4372	Transposase
ABEKA_3262	COG2963	transposase activity
ABEKA_3265	COG2433	Pfam Transposase IS66
ABEKA_3266	COG4372	Transposase
ABEKA_3268	COG0154	amidase activity
ABEKA_3284	COG0659	secondary active sulfate transmembrane transporter activity
ABEKA_3295	COG0589	response to stress
ABEKA_3296	COG0659	secondary active sulfate transmembrane transporter activity
ABEKA_3565	COG2826	transposase and inactivated derivatives, IS30 family
ABEKA_3568	COG3385	transposase activity
ABEKA_3573	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
ABEKA_3585	COG1280	lysine exporter protein (LysE YggA)
ABWEK_A0005	COG1063	alcohol dehydrogenase
ABWEK_A0006	COG4716	Myosin-crossreactive antigen
ABWEK_A0012	COG4372	Transposase
ABWEK_A0016	COG2433	Pfam Transposase IS66
ABWEK_A0017	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABWEK_A0020	COG4372	Transposase
ABWEK_A0033	COG2217	Heavy metal translocating P-type atpase
ABWEK_A0034	COG3174	membrane
ABWEK_A0035	COG2205	protein histidine kinase activity
ABWEK_A0038	COG2132	Multicopper oxidase
ABWEK_A0062	COG4221	oxidoreductase activity
ABWEK_A0063	COG0583	DNA-binding transcription factor activity
ABWEK_A0064	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABWEK_A0065	COG3321	synthase
ABWEK_A0065	COG0604	alcohol dehydrogenase
ABWEK_A0068	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ABWEK_A0070	COG1979	alcohol dehydrogenase
ABWEK_A0072	COG1902	pentaerythritol trinitrate reductase activity
ABWEK_A0074	COG1309	transcriptional regulator
ABWEK_A0075	COG2130	NADP-dependent
ABWEK_A0078	COG3293	Transposase
ABWEK_A0084	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABWEK_A0086	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABWEK_A0087	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABWEK_A0088	COG0730	response to heat
ABWEK_A0093	COG0583	DNA-binding transcription factor activity
ABWEK_A0095	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABWEK_A0096	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ABWEK_A0100	COG3189	MarR family transcriptional regulator
ABWEK_A0113	COG3550	peptidyl-serine autophosphorylation
ABWEK_A0116	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABWEK_A0116	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABWEK_A0116	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ABWEK_A0117	COG1105	Belongs to the carbohydrate kinase PfkB family
ABWEK_A0118	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABWEK_A0118	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABWEK_A0120	COG2186	Transcriptional regulator
ABWEK_A0123	COG0642	Histidine kinase
ABWEK_A0125	COG4106	trans-aconitate 2-methyltransferase activity
ABWEK_A0127	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABWEK_A0127	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABWEK_A0128	COG2226	methyltransferase
ABWEK_A0128	COG2267	carboxylic ester hydrolase activity
ABWEK_A0129	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABWEK_A0133	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABWEK_A0137	COG4773	Receptor
ABWEK_A0142	COG1454	alcohol dehydrogenase
ABWEK_A0146	COG4774	siderophore transport
ABWEK_A0150	COG1192	Involved in chromosome partitioning
ABWEK_A0153	COG3293	Transposase
ABWEK_A0164	COG0659	secondary active sulfate transmembrane transporter activity
ABWEK_A0165	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABWEK_A0166	COG3657	addiction module killer protein
ABWEK_A0184	COG1373	ATPase (AAA superfamily
ABWEK_A0201	COG2801	Transposase and inactivated derivatives
ABWEK_A0209	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABWEK_A0213	COG1846	Transcriptional regulator
ABWEK_A0214	COG1764	response to oxidative stress
ABWEK_A0219	COG3335	DDE superfamily endonuclease
ABWEK_D0011	COG0753	catalase activity
ABWEK_F0009	COG2431	L-lysine efflux transmembrane transporter activity
ABWEK_J0002	COG0753	catalase activity
ABWEK_J0003	COG0783	Belongs to the Dps family