locus-tag	class	description
FOB21_00005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOB21_00005	COG1918	ferrous iron import across plasma membrane
FOB21_00015	COG3316	Transposase and inactivated derivatives
FOB21_00025	COG0281	malic enzyme
FOB21_00035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_00045	COG0583	DNA-binding transcription factor activity
FOB21_00075	COG3657	addiction module killer protein
FOB21_00080	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_00085	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FOB21_00090	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOB21_00100	COG0583	DNA-binding transcription factor activity
FOB21_00105	COG3077	Addiction module antitoxin, RelB DinJ family
FOB21_00135	COG2801	Transposase and inactivated derivatives
FOB21_00150	COG3293	Transposase
FOB21_00185	COG3293	Transposase
FOB21_00195	COG1192	Involved in chromosome partitioning
FOB21_00215	COG3385	transposase activity
FOB21_00235	COG4774	siderophore transport
FOB21_00255	COG1454	alcohol dehydrogenase
FOB21_00280	COG4773	Receptor
FOB21_00305	COG2267	carboxylic ester hydrolase activity
FOB21_00305	COG2226	methyltransferase
FOB21_00320	COG4106	trans-aconitate 2-methyltransferase activity
FOB21_00330	COG0642	Histidine kinase
FOB21_00345	COG2186	Transcriptional regulator
FOB21_00355	COG4628	conserved protein (DUF2132)
FOB21_00380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB21_00385	COG3550	peptidyl-serine autophosphorylation
FOB21_00460	COG1203	CRISPR-associated helicase, Cas3
FOB21_00495	COG3540	Alkaline phosphatase
FOB21_00510	COG3293	Transposase
FOB21_00520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB21_00520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB21_00525	COG1105	Belongs to the carbohydrate kinase PfkB family
FOB21_00530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB21_00530	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FOB21_00530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOB21_00555	COG0475	glutathione-regulated potassium exporter activity
FOB21_00555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_00575	COG1309	transcriptional regulator
FOB21_00580	COG0604	alcohol dehydrogenase
FOB21_00605	COG2801	Transposase and inactivated derivatives
FOB21_00665	COG0730	response to heat
FOB21_00670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_00675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB21_00705	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB21_00735	COG3293	Transposase
FOB21_00740	COG3539	Fimbrial protein
FOB21_00790	COG0604	alcohol dehydrogenase
FOB21_00790	COG3321	synthase
FOB21_00795	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB21_00800	COG0583	DNA-binding transcription factor activity
FOB21_00805	COG4221	oxidoreductase activity
FOB21_00830	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_00840	COG4372	Transposase
FOB21_00855	COG0640	Transcriptional regulator
FOB21_00875	COG3316	Transposase and inactivated derivatives
FOB21_00885	COG2132	Multicopper oxidase
FOB21_00890	COG2801	Transposase and inactivated derivatives
FOB21_00895	COG3316	Transposase and inactivated derivatives
FOB21_00935	COG2205	protein histidine kinase activity
FOB21_00940	COG3174	membrane
FOB21_00945	COG2217	Heavy metal translocating P-type atpase
FOB21_01005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_01010	COG3316	Transposase and inactivated derivatives
FOB21_01090	COG0542	response to heat
FOB21_01120	COG0372	Belongs to the citrate synthase family
FOB21_01160	COG0753	catalase activity
FOB21_01165	COG2814	Major facilitator Superfamily
FOB21_01185	COG0439	Biotin carboxylase
FOB21_01195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB21_01200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB21_01235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB21_01275	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_01290	COG0596	Alpha beta hydrolase
FOB21_01305	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_01315	COG2801	Transposase and inactivated derivatives
FOB21_01320	COG0300	oxidoreductase activity
FOB21_01350	COG0642	Histidine kinase
FOB21_01355	COG0745	RESPONSE REGULATOR receiver
FOB21_01360	COG2194	sulfuric ester hydrolase activity
FOB21_01385	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_01390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB21_01395	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB21_01415	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_01425	COG1024	Enoyl-CoA hydratase
FOB21_01430	COG1960	acyl-CoA dehydrogenase activity
FOB21_01435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_01450	COG0583	DNA-binding transcription factor activity
FOB21_01470	COG2814	Major facilitator Superfamily
FOB21_01480	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_01495	COG1960	acyl-CoA dehydrogenase activity
FOB21_01505	COG1024	Enoyl-CoA hydratase
FOB21_01510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB21_01515	COG0235	Class ii aldolase
FOB21_01525	COG0183	Belongs to the thiolase family
FOB21_01530	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_01535	COG1024	Enoyl-CoA hydratase
FOB21_01540	COG2814	Major facilitator Superfamily
FOB21_01550	COG2814	Major facilitator Superfamily
FOB21_01555	COG5001	Diguanylate cyclase
FOB21_01560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_01565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOB21_01570	COG2814	Major facilitator Superfamily
FOB21_01575	COG1960	acyl-CoA dehydrogenase activity
FOB21_01580	COG1960	acyl-CoA dehydrogenase activity
FOB21_01590	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB21_01590	COG0644	oxidoreductase
FOB21_01595	COG1944	ATP diphosphatase activity
FOB21_01615	COG1309	transcriptional regulator
FOB21_01620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB21_01635	COG0583	DNA-binding transcription factor activity
FOB21_01645	COG0515	serine threonine protein kinase
FOB21_01650	COG2116	formate transmembrane transporter activity
FOB21_01655	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FOB21_01675	COG3293	Transposase
FOB21_01680	COG2223	nitrite transmembrane transporter activity
FOB21_01685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOB21_01690	COG4149	molybdate abc transporter
FOB21_01695	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB21_01700	COG0303	'Molybdopterin
FOB21_01705	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB21_01705	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB21_01710	COG0314	molybdopterin synthase activity
FOB21_01720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB21_01730	COG0243	molybdopterin cofactor binding
FOB21_01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_01750	COG1116	anion transmembrane transporter activity
FOB21_01750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_01755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB21_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB21_01790	COG0864	Transcriptional regulator
FOB21_01840	COG0439	Biotin carboxylase
FOB21_01865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB21_01880	COG1017	nitric oxide dioxygenase activity
FOB21_01880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_01885	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_01890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB21_01900	COG2814	Major facilitator Superfamily
FOB21_01905	COG0583	DNA-binding transcription factor activity
FOB21_01910	COG4948	Mandelate Racemase Muconate Lactonizing
FOB21_01915	COG4829	muconolactone delta-isomerase
FOB21_01925	COG4638	Rieske (2fe-2S)
FOB21_01930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FOB21_01935	COG0633	Ferredoxin
FOB21_01935	COG0543	2 iron, 2 sulfur cluster binding
FOB21_01940	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_01945	COG3135	benzoate transporter
FOB21_01950	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOB21_01955	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_01960	COG0183	Belongs to the thiolase family
FOB21_01965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_01990	COG0183	Belongs to the thiolase family
FOB21_01995	COG1960	acyl-CoA dehydrogenase activity
FOB21_02010	COG0789	Transcriptional regulator
FOB21_02020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB21_02025	COG0640	Transcriptional regulator
FOB21_02045	COG3122	Protein conserved in bacteria
FOB21_02050	COG0668	transmembrane transport
FOB21_02055	COG1132	(ABC) transporter
FOB21_02065	COG0509	glycine decarboxylation via glycine cleavage system
FOB21_02070	COG2814	Major facilitator Superfamily
FOB21_02085	COG2801	Transposase and inactivated derivatives
FOB21_02090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB21_02100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FOB21_02105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB21_02160	COG1525	nuclease
FOB21_02170	COG1294	oxidase, subunit
FOB21_02175	COG1271	oxidase subunit
FOB21_02190	COG2169	Transcriptional regulator
FOB21_02195	COG1960	acyl-CoA dehydrogenase activity
FOB21_02200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB21_02205	COG2207	Transcriptional regulator
FOB21_02210	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_02215	COG0730	response to heat
FOB21_02220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB21_02285	COG1960	acyl-CoA dehydrogenase activity
FOB21_02290	COG0456	acetyltransferase
FOB21_02325	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FOB21_02340	COG0552	protein localization to endoplasmic reticulum
FOB21_02345	COG0612	Peptidase, M16
FOB21_02375	COG0517	IMP dehydrogenase activity
FOB21_02380	COG0133	tryptophan synthase activity
FOB21_02390	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB21_02410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB21_02440	COG0537	adenosine 5'-monophosphoramidase activity
FOB21_02460	COG1294	oxidase, subunit
FOB21_02465	COG4890	Cyd operon protein YbgT
FOB21_02475	COG0772	Belongs to the SEDS family
FOB21_02490	COG0148	phosphopyruvate hydratase activity
FOB21_02525	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_02525	COG1902	pentaerythritol trinitrate reductase activity
FOB21_02540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB21_02545	COG0583	DNA-binding transcription factor activity
FOB21_02550	COG0024	Methionine aminopeptidase
FOB21_02555	COG1114	Component of the transport system for branched-chain amino acids
FOB21_02610	COG1570	exodeoxyribonuclease VII activity
FOB21_02620	COG3385	transposase activity
FOB21_02655	COG0729	surface antigen
FOB21_02660	COG0477	Major facilitator Superfamily
FOB21_02675	COG3293	Transposase
FOB21_02705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB21_02715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_02720	COG1960	acyl-CoA dehydrogenase activity
FOB21_02740	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB21_02745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB21_02760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_02785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB21_02790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB21_02795	COG1845	cytochrome c oxidase, subunit III
FOB21_02800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB21_02810	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB21_02825	COG0305	Participates in initiation and elongation during chromosome replication
FOB21_02830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB21_02845	COG1305	Transglutaminase-like
FOB21_02855	COG2308	Evidence 4 Homologs of previously reported genes of
FOB21_02865	COG0069	glutamate synthase activity
FOB21_02885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB21_02890	COG1454	alcohol dehydrogenase
FOB21_02895	COG0824	Thioesterase
FOB21_02900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB21_02925	COG0183	Belongs to the thiolase family
FOB21_02930	COG3385	transposase activity
FOB21_02945	COG0583	DNA-binding transcription factor activity
FOB21_02950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB21_02960	COG3135	benzoate transporter
FOB21_02975	COG0589	response to stress
FOB21_02980	COG0589	response to stress
FOB21_02990	COG0308	aminopeptidase N
FOB21_03010	COG1253	flavin adenine dinucleotide binding
FOB21_03030	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB21_03035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB21_03050	COG2431	L-lysine efflux transmembrane transporter activity
FOB21_03065	COG0776	regulation of translation
FOB21_03085	COG0590	tRNA wobble adenosine to inosine editing
FOB21_03095	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB21_03125	COG1309	transcriptional regulator
FOB21_03130	COG0084	hydrolase, TatD family'
FOB21_03150	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB21_03155	COG1132	(ABC) transporter
FOB21_03165	COG0811	peptide transport
FOB21_03170	COG1475	DNA binding
FOB21_03175	COG1192	Involved in chromosome partitioning
FOB21_03185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOB21_03190	COG3178	'Phosphotransferase
FOB21_03200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB21_03205	COG1923	regulation of RNA biosynthetic process
FOB21_03215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB21_03220	COG0802	atpase or kinase
FOB21_03260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_03280	COG1643	Atp-dependent helicase
FOB21_03285	COG0450	alkyl hydroperoxide reductase
FOB21_03305	COG3634	alkyl hydroperoxide reductase activity
FOB21_03340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOB21_03340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB21_03420	COG0656	L-ascorbic acid biosynthetic process
FOB21_03475	COG4372	Transposase
FOB21_03510	COG4372	Transposase
FOB21_03560	COG0583	DNA-binding transcription factor activity
FOB21_03580	COG2233	PERMEase
FOB21_03600	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FOB21_03630	COG0583	DNA-binding transcription factor activity
FOB21_03635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_03640	COG4266	Belongs to the allantoicase family
FOB21_03650	COG3385	transposase activity
FOB21_03660	COG2233	PERMEase
FOB21_03665	COG2351	hydroxyisourate hydrolase activity
FOB21_03685	COG0804	urea catabolic process
FOB21_03700	COG0831	urea catabolic process
FOB21_03705	COG0829	nickel cation binding
FOB21_03720	COG0830	nickel cation binding
FOB21_03755	COG4372	Transposase
FOB21_03775	COG4372	Transposase
FOB21_03800	COG0204	Acyl-transferase
FOB21_03825	COG0012	GTP binding
FOB21_03840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB21_03860	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB21_03870	COG0386	Belongs to the glutathione peroxidase family
FOB21_03875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB21_03880	COG0436	Aminotransferase
FOB21_03905	COG2351	hydroxyisourate hydrolase activity
FOB21_03930	COG1686	Belongs to the peptidase S11 family
FOB21_03935	COG1252	NADH dehydrogenase
FOB21_03955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB21_03970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FOB21_03985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB21_03990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB21_03995	COG0527	aspartate kinase activity
FOB21_04005	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB21_04025	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB21_04030	COG2252	PERMEase
FOB21_04055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB21_04060	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB21_04070	COG0693	protein deglycase activity
FOB21_04075	COG1960	acyl-CoA dehydrogenase activity
FOB21_04080	COG1301	dicarboxylic acid transport
FOB21_04090	COG3139	Protein of unknown function (DUF1315)
FOB21_04095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB21_04100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB21_04110	COG0494	nUDIX hydrolase
FOB21_04120	COG0642	Histidine kinase
FOB21_04125	COG0745	RESPONSE REGULATOR receiver
FOB21_04135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOB21_04145	COG1720	tRNA m6t6A37 methyltransferase activity
FOB21_04180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB21_04185	COG3634	alkyl hydroperoxide reductase activity
FOB21_04205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB21_04250	COG3328	transposase activity
FOB21_04265	COG3706	GGDEF domain
FOB21_04410	COG2369	cell adhesion
FOB21_04415	COG3567	Phage-associated protein, HI1409 family
FOB21_04420	COG5410	chromosome segregation
FOB21_04570	COG1131	(ABC) transporter
FOB21_04575	COG0842	Transport permease protein
FOB21_04590	COG2951	lytic endotransglycosylase activity
FOB21_04615	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB21_04620	COG0024	Methionine aminopeptidase
FOB21_04630	COG0534	Mate efflux family protein
FOB21_04655	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB21_04670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB21_04675	COG0571	ribonuclease III activity
FOB21_04700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB21_04730	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_04735	COG4372	Transposase
FOB21_04755	COG2826	transposase and inactivated derivatives, IS30 family
FOB21_04790	COG4372	Transposase
FOB21_04805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB21_04815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_04820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_04835	COG4208	sulfate ABC transporter
FOB21_04840	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB21_04845	COG0583	DNA-binding transcription factor activity
FOB21_04865	COG0602	queuosine metabolic process
FOB21_04870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB21_04880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB21_04895	COG0583	DNA-binding transcription factor activity
FOB21_04900	COG1051	belongs to the nudix hydrolase family
FOB21_04900	COG1056	cytidyltransferase-related domain
FOB21_04910	COG0778	Nitroreductase
FOB21_04915	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FOB21_04940	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB21_04940	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB21_04960	COG2255	four-way junction helicase activity
FOB21_04975	COG1473	amidohydrolase
FOB21_04980	COG0824	Thioesterase
FOB21_05000	COG0823	Involved in the tonB-independent uptake of proteins
FOB21_05020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB21_05040	COG3385	transposase activity
FOB21_05065	COG2267	carboxylic ester hydrolase activity
FOB21_05070	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB21_05075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB21_05080	COG0628	permease
FOB21_05105	COG2333	competence protein COMEC
FOB21_05105	COG0658	competence protein
FOB21_05110	COG1136	(ABC) transporter
FOB21_05130	COG1671	Belongs to the UPF0178 family
FOB21_05155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_05175	COG3385	transposase activity
FOB21_05200	COG1280	lysine exporter protein (LysE YggA)
FOB21_05205	COG1522	sequence-specific DNA binding
FOB21_05215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB21_05220	COG2267	carboxylic ester hydrolase activity
FOB21_05230	COG0019	diaminopimelate decarboxylase activity
FOB21_05240	COG1113	amino acid transport
FOB21_05245	COG1115	amino acid carrier protein
FOB21_05285	COG3385	transposase activity
FOB21_05290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOB21_05295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB21_05300	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB21_05305	COG5001	Diguanylate cyclase
FOB21_05305	COG1716	ATPase activity
FOB21_05320	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOB21_05340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB21_05355	COG0037	tRNA processing
FOB21_05360	COG1196	nuclear chromosome segregation
FOB21_05360	COG0741	lytic transglycosylase activity
FOB21_05360	COG0739	heme binding
FOB21_05365	COG0501	Belongs to the peptidase M48B family
FOB21_05375	COG2239	Acts as a magnesium transporter
FOB21_05400	COG1253	flavin adenine dinucleotide binding
FOB21_05435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOB21_05445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB21_05475	COG0505	Belongs to the CarA family
FOB21_05480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB21_05490	COG1309	transcriptional regulator
FOB21_05495	COG0251	oxidation-reduction process
FOB21_05500	COG0110	maltose O-acetyltransferase activity
FOB21_05510	COG3293	Transposase
FOB21_05530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB21_05555	COG0564	pseudouridine synthase activity
FOB21_05565	COG0358	DNA primase activity
FOB21_05570	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB21_05580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB21_05610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB21_05615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB21_05640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOB21_05665	COG0586	Pfam SNARE associated Golgi protein
FOB21_05690	COG2921	Belongs to the UPF0250 family
FOB21_05695	COG0321	lipoyl(octanoyl) transferase activity
FOB21_05710	COG0531	amino acid
FOB21_05720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOB21_05725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB21_05725	COG1648	precorrin-2 dehydrogenase activity
FOB21_05730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB21_05740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB21_05750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB21_05765	COG0671	phosphoesterase, PA-phosphatase related
FOB21_05770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_05780	COG1538	Outer membrane efflux protein
FOB21_05785	COG0393	Putative heavy-metal-binding
FOB21_05790	COG0393	Putative heavy-metal-binding
FOB21_05820	COG5001	Diguanylate cyclase
FOB21_05820	COG4251	negative regulation of phosphorylation
FOB21_05820	COG2203	Gaf domain
FOB21_05820	COG3706	GGDEF domain
FOB21_05835	COG4681	YaeQ
FOB21_05840	COG0523	cobalamin synthesis protein
FOB21_05875	COG2814	Major facilitator Superfamily
FOB21_05885	COG1607	acyl-coa hydrolase
FOB21_05890	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB21_05895	COG2059	Chromate
FOB21_05900	COG1115	amino acid carrier protein
FOB21_05905	COG0786	glutamate:sodium symporter activity
FOB21_05920	COG1289	transmembrane transporter activity
FOB21_05930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB21_05990	COG2832	Protein of unknown function (DUF454)
FOB21_06020	COG0840	transmembrane signaling receptor activity
FOB21_06060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_06105	COG0489	protein tyrosine kinase activity
FOB21_06120	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB21_06120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB21_06135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB21_06140	COG0004	ammonium transporteR
FOB21_06165	COG2081	HI0933 family
FOB21_06175	COG0668	transmembrane transport
FOB21_06185	COG4302	ethanolamine ammonia-lyase activity
FOB21_06195	COG0531	amino acid
FOB21_06215	COG0583	DNA-binding transcription factor activity
FOB21_06220	COG1278	Cold shock
FOB21_06245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_06250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB21_06255	COG0713	ATP synthesis coupled electron transport
FOB21_06265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_06280	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOB21_06300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB21_06310	COG2205	protein histidine kinase activity
FOB21_06315	COG0745	RESPONSE REGULATOR receiver
FOB21_06320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB21_06320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB21_06325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOB21_06330	COG3152	Membrane
FOB21_06335	COG2314	TM2 domain
FOB21_06345	COG4772	TonB-dependent receptor
FOB21_06365	COG3152	Membrane
FOB21_06380	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_06380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB21_06380	COG0351	phosphomethylpyrimidine kinase
FOB21_06415	COG2824	Alkylphosphonate utilization operon protein PhnA
FOB21_06440	COG0564	pseudouridine synthase activity
FOB21_06485	COG0354	folic acid binding
FOB21_06500	COG3385	transposase activity
FOB21_06510	COG1902	pentaerythritol trinitrate reductase activity
FOB21_06540	COG2233	PERMEase
FOB21_06550	COG0833	amino acid
FOB21_06560	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOB21_06560	COG2885	chlorophyll binding
FOB21_06570	COG0183	Belongs to the thiolase family
FOB21_06590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_06595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB21_06600	COG2207	Transcriptional regulator
FOB21_06605	COG0183	Belongs to the thiolase family
FOB21_06610	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_06610	COG1024	Enoyl-CoA hydratase
FOB21_06630	COG1272	protein, Hemolysin III
FOB21_06635	COG0477	Major facilitator Superfamily
FOB21_06645	COG1408	metallophosphoesterase
FOB21_06650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB21_06665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB21_06715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB21_06720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB21_06725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB21_06730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB21_06735	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB21_06740	COG0625	glutathione transferase activity
FOB21_06745	COG2969	positive regulation of protein catabolic process
FOB21_06800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOB21_06805	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOB21_06815	COG0653	protein targeting
FOB21_06820	COG0450	alkyl hydroperoxide reductase
FOB21_06835	COG0285	dihydrofolate synthase activity
FOB21_06895	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB21_06905	COG1704	LemA family
FOB21_06920	COG1862	Preprotein translocase
FOB21_06940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB21_06955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOB21_06970	COG2084	Dehydrogenase
FOB21_06975	COG3622	Belongs to the hyi family
FOB21_06985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOB21_06990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB21_06995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOB21_07000	COG2814	Major facilitator Superfamily
FOB21_07010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB21_07020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB21_07025	COG2003	Belongs to the UPF0758 family
FOB21_07030	COG3781	membrane
FOB21_07045	COG2350	Protein conserved in bacteria
FOB21_07080	COG1607	acyl-coa hydrolase
FOB21_07095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB21_07095	COG3453	Protein conserved in bacteria
FOB21_07140	COG1183	phosphatidylcholine synthase activity
FOB21_07145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB21_07175	COG3385	transposase activity
FOB21_07190	COG0741	lytic transglycosylase activity
FOB21_07190	COG0739	heme binding
FOB21_07190	COG1196	nuclear chromosome segregation
FOB21_07195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB21_07200	COG1702	phosphate starvation-inducible protein PhoH
FOB21_07300	COG1295	ribonuclease BN
FOB21_07320	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB21_07360	COG0557	exoribonuclease II activity
FOB21_07370	COG0339	signal peptide processing
FOB21_07375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FOB21_07410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB21_07415	COG1960	acyl-CoA dehydrogenase activity
FOB21_07420	COG2072	flavoprotein involved in K transport
FOB21_07425	COG0203	ribosomal protein L17
FOB21_07430	COG0202	RNA polymerase activity
FOB21_07435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB21_07440	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB21_07445	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB21_07450	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB21_07470	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB21_07480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB21_07485	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB21_07495	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB21_07535	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB21_07545	COG0089	rRNA binding
FOB21_07550	COG0088	Forms part of the polypeptide exit tunnel
FOB21_07570	COG0626	cystathionine gamma-synthase activity
FOB21_07575	COG0433	COG0433 Predicted ATPase
FOB21_07580	COG1017	nitric oxide dioxygenase activity
FOB21_07580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_07585	COG1959	2 iron, 2 sulfur cluster binding
FOB21_07595	COG1301	dicarboxylic acid transport
FOB21_07600	COG1946	Acyl-CoA thioesterase
FOB21_07605	COG2937	Belongs to the GPAT DAPAT family
FOB21_07615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB21_07620	COG1040	competence protein
FOB21_07625	COG0494	nUDIX hydrolase
FOB21_07635	COG0598	Magnesium transport protein CorA
FOB21_07655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB21_07660	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB21_07665	COG1127	ABC transporter
FOB21_07670	COG0513	Belongs to the DEAD box helicase family
FOB21_07690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB21_07695	COG0408	coproporphyrinogen oxidase activity
FOB21_07710	COG1960	acyl-CoA dehydrogenase activity
FOB21_07715	COG1278	Cold shock
FOB21_07725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB21_07735	COG0534	Mate efflux family protein
FOB21_07745	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB21_07750	COG0254	rRNA binding
FOB21_07755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB21_07785	COG1192	Involved in chromosome partitioning
FOB21_07790	COG0628	permease
FOB21_07800	COG1289	transmembrane transporter activity
FOB21_07805	COG2814	Major facilitator Superfamily
FOB21_07825	COG0277	FAD linked oxidase domain protein
FOB21_07830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB21_07880	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB21_07885	COG5380	lipid catabolic process
FOB21_07890	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB21_07895	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FOB21_07910	COG0335	large ribosomal subunit rRNA binding
FOB21_07920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB21_07925	COG0228	four-way junction DNA binding
FOB21_07975	COG0194	GDP metabolic process
FOB21_07980	COG1758	RNA polymerase activity
FOB21_07985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB21_07995	COG2906	2 iron, 2 sulfur cluster binding
FOB21_08005	COG3307	-O-antigen
FOB21_08030	COG1704	LemA family
FOB21_08035	COG0493	'glutamate synthase
FOB21_08040	COG0069	glutamate synthase activity
FOB21_08040	COG0067	glutamate synthase
FOB21_08040	COG0070	glutamate synthase
FOB21_08095	COG2226	methyltransferase
FOB21_08105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOB21_08110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB21_08130	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB21_08150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB21_08170	COG0488	(ABC) transporter
FOB21_08180	COG4221	oxidoreductase activity
FOB21_08185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB21_08200	COG2111	Na H antiporter
FOB21_08200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB21_08205	COG1006	Multisubunit Na H antiporter MnhC subunit
FOB21_08210	COG0651	ATP synthesis coupled electron transport
FOB21_08215	COG1863	multisubunit Na H antiporter MnhE subunit
FOB21_08220	COG2212	antiporter activity
FOB21_08235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB21_08245	COG0195	Participates in both transcription termination and antitermination
FOB21_08250	COG0779	Required for maturation of 30S ribosomal subunits
FOB21_08305	COG0237	dephospho-CoA kinase activity
FOB21_08315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB21_08320	COG3123	guanosine phosphorylase activity
FOB21_08325	COG0497	DNA recombination
FOB21_08335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB21_08345	COG1132	(ABC) transporter
FOB21_08375	COG0494	nUDIX hydrolase
FOB21_08385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOB21_08390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB21_08400	COG0772	Belongs to the SEDS family
FOB21_08425	COG4974	Belongs to the 'phage' integrase family
FOB21_08430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_08440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOB21_08445	COG1686	Belongs to the peptidase S11 family
FOB21_08450	COG2197	response regulator
FOB21_08465	COG0793	Belongs to the peptidase S41A family
FOB21_08465	COG3409	Peptidoglycan-binding domain 1 protein
FOB21_08470	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOB21_08475	COG0795	lipopolysaccharide-transporting ATPase activity
FOB21_08480	COG0795	lipopolysaccharide-transporting ATPase activity
FOB21_08500	COG0586	Pfam SNARE associated Golgi protein
FOB21_08515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB21_08515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB21_08525	COG0004	ammonium transporteR
FOB21_08530	COG0347	Belongs to the P(II) protein family
FOB21_08540	COG0606	chelatase, subunit chli
FOB21_08555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOB21_08570	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_08580	COG0477	Major facilitator Superfamily
FOB21_08585	COG2860	membrane
FOB21_08595	COG1253	flavin adenine dinucleotide binding
FOB21_08630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB21_08635	COG0477	Major facilitator Superfamily
FOB21_08655	COG2814	Major facilitator Superfamily
FOB21_08705	COG0758	DNA mediated transformation
FOB21_08715	COG0697	spore germination
FOB21_08720	COG0386	Belongs to the glutathione peroxidase family
FOB21_08735	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_08750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB21_08760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB21_08800	COG1121	(ABC) transporter
FOB21_08805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB21_08815	COG2837	iron assimilation
FOB21_08830	COG0436	Aminotransferase
FOB21_08835	COG0534	Mate efflux family protein
FOB21_08860	COG0625	glutathione transferase activity
FOB21_08870	COG3706	GGDEF domain
FOB21_08875	COG3706	GGDEF domain
FOB21_08880	COG1715	Restriction endonuclease
FOB21_08885	COG0519	Catalyzes the synthesis of GMP from XMP
FOB21_08885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB21_08890	COG0586	Pfam SNARE associated Golgi protein
FOB21_08905	COG1192	Involved in chromosome partitioning
FOB21_08915	COG0271	Belongs to the BolA IbaG family
FOB21_08950	COG3756	Protein conserved in bacteria
FOB21_09030	COG1538	Outer membrane efflux protein
FOB21_09350	COG0281	malic enzyme
FOB21_09370	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB21_09380	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOB21_09385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB21_09395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOB21_09400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB21_09410	COG4372	Transposase
FOB21_09435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOB21_09450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB21_09465	COG0297	glycogen (starch) synthase activity
FOB21_09470	COG0438	transferase activity, transferring glycosyl groups
FOB21_09475	COG0438	transferase activity, transferring glycosyl groups
FOB21_09495	COG1051	belongs to the nudix hydrolase family
FOB21_09505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB21_09525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB21_09535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB21_09545	COG0438	transferase activity, transferring glycosyl groups
FOB21_09550	COG0438	transferase activity, transferring glycosyl groups
FOB21_09555	COG0438	transferase activity, transferring glycosyl groups
FOB21_09580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB21_09620	COG1194	a g-specific adenine glycosylase
FOB21_09625	COG0739	heme binding
FOB21_09635	COG2818	Glycosylase
FOB21_09640	COG1064	alcohol dehydrogenase
FOB21_09680	COG0675	Transposase, IS605 OrfB family
FOB21_09700	COG1309	transcriptional regulator
FOB21_09725	COG2233	PERMEase
FOB21_09745	COG0129	dihydroxy-acid dehydratase activity
FOB21_09770	COG0129	dihydroxy-acid dehydratase activity
FOB21_09785	COG0428	transporter
FOB21_09795	COG0733	neurotransmitter:sodium symporter activity
FOB21_09800	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_09810	COG0693	protein deglycase activity
FOB21_09840	COG2814	Major facilitator Superfamily
FOB21_09845	COG2814	Major facilitator Superfamily
FOB21_09875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB21_09950	COG0488	(ABC) transporter
FOB21_09955	COG1063	alcohol dehydrogenase
FOB21_09960	COG0187	DNA topoisomerase II activity
FOB21_09970	COG0592	DNA-directed DNA polymerase activity
FOB21_09975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB21_09980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOB21_09985	COG0594	ribonuclease P activity
FOB21_09990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB21_09995	COG0706	membrane insertase activity
FOB21_10005	COG3385	transposase activity
FOB21_10015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_10030	COG0402	S-adenosylhomocysteine deaminase activity
FOB21_10040	COG0861	Integral membrane protein TerC family
FOB21_10050	COG2388	GCN5-related N-acetyl-transferase
FOB21_10075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB21_10090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB21_10095	COG2951	lytic endotransglycosylase activity
FOB21_10100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB21_10105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB21_10140	COG2133	pyrroloquinoline quinone binding
FOB21_10155	COG1047	Peptidyl-prolyl cis-trans
FOB21_10160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB21_10165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB21_10170	COG0196	riboflavin kinase activity
FOB21_10180	COG1309	transcriptional regulator
FOB21_10185	COG1116	anion transmembrane transporter activity
FOB21_10190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB21_10195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_10200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_10205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB21_10210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB21_10210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB21_10230	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_10235	COG0546	phosphoglycolate phosphatase activity
FOB21_10240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB21_10245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB21_10250	COG1309	transcriptional regulator
FOB21_10255	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB21_10270	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB21_10275	COG0728	peptidoglycan biosynthetic process
FOB21_10280	COG5487	UPF0391 membrane protein
FOB21_10285	COG2983	Belongs to the UPF0260 family
FOB21_10290	COG3300	MHYT domain
FOB21_10290	COG5001	Diguanylate cyclase
FOB21_10295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB21_10300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB21_10310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB21_10315	COG2814	Major facilitator Superfamily
FOB21_10320	COG1335	isochorismatase
FOB21_10325	COG0385	Bile acid
FOB21_10355	COG3385	transposase activity
FOB21_10365	COG0753	catalase activity
FOB21_10405	COG2733	membrane
FOB21_10420	COG2918	glutathione biosynthetic process
FOB21_10425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOB21_10435	COG3150	esterase
FOB21_10450	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB21_10455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB21_10465	COG0410	ABC transporter
FOB21_10480	COG1247	-acetyltransferase
FOB21_10510	COG3706	GGDEF domain
FOB21_10540	COG0708	Exodeoxyribonuclease III
FOB21_10545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB21_10550	COG1278	Cold shock
FOB21_10565	COG2132	Multicopper oxidase
FOB21_10575	COG3293	Transposase
FOB21_10585	COG0189	ligase activity
FOB21_10600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB21_10610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB21_10620	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOB21_10645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB21_10655	COG2119	membrane
FOB21_10660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_10660	COG0426	domain, Protein
FOB21_10685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB21_10710	COG1902	pentaerythritol trinitrate reductase activity
FOB21_10715	COG1519	Transferase
FOB21_10720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB21_10725	COG0668	transmembrane transport
FOB21_10730	COG3152	Membrane
FOB21_10735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB21_10745	COG0415	Belongs to the DNA photolyase family
FOB21_10750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_10755	COG0431	NADPH-dependent FMN reductase
FOB21_10770	COG2205	protein histidine kinase activity
FOB21_10770	COG0784	Response regulator, receiver
FOB21_10775	COG3162	membrane
FOB21_10780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_10790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB21_10805	COG3706	GGDEF domain
FOB21_10825	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_10825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOB21_10825	COG0351	phosphomethylpyrimidine kinase
FOB21_10835	COG2814	Major facilitator Superfamily
FOB21_10845	COG0450	alkyl hydroperoxide reductase
FOB21_10850	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
FOB21_10945	COG0305	Participates in initiation and elongation during chromosome replication
FOB21_10985	COG3158	transport of potassium into the cell
FOB21_11020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOB21_11055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOB21_11120	COG0183	Belongs to the thiolase family
FOB21_11125	COG1024	Enoyl-CoA hydratase
FOB21_11125	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_11150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB21_11170	COG3275	phosphorelay sensor kinase activity
FOB21_11180	COG0181	hydroxymethylbilane synthase activity
FOB21_11200	COG0824	Thioesterase
FOB21_11230	COG0546	phosphoglycolate phosphatase activity
FOB21_11260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB21_11285	COG0081	regulation of translation
FOB21_11290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB21_11295	COG0222	ribosome binding
FOB21_11300	COG0085	RNA polymerase activity
FOB21_11305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB21_11325	COG2056	Na+-H+ antiporter family
FOB21_11330	COG3047	cAMP biosynthetic process
FOB21_11340	COG0326	Molecular chaperone. Has ATPase activity
FOB21_11370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOB21_11375	COG0427	acetyl-CoA hydrolase
FOB21_11380	COG2205	protein histidine kinase activity
FOB21_11385	COG0745	RESPONSE REGULATOR receiver
FOB21_11405	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB21_11435	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FOB21_11440	COG1074	ATP-dependent DNA helicase activity
FOB21_11445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOB21_11450	COG3293	Transposase
FOB21_11455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB21_11460	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB21_11465	COG2841	Protein conserved in bacteria
FOB21_11470	COG0789	Transcriptional regulator
FOB21_11480	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB21_11485	COG0475	glutathione-regulated potassium exporter activity
FOB21_11485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_11490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB21_11510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB21_11515	COG4535	Mg2 and Co2 transporter CorC
FOB21_11520	COG0425	Belongs to the sulfur carrier protein TusA family
FOB21_11525	COG0644	oxidoreductase
FOB21_11525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FOB21_11535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOB21_11550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB21_11560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FOB21_11570	COG0493	'glutamate synthase
FOB21_11595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB21_11615	COG0751	glycine-tRNA ligase activity
FOB21_11640	COG0471	metal ion transport
FOB21_11650	COG1983	PspC domain protein
FOB21_11680	COG1530	ribonuclease E activity
FOB21_11685	COG0564	pseudouridine synthase activity
FOB21_11695	COG0546	phosphoglycolate phosphatase activity
FOB21_11700	COG3971	2-oxopent-4-enoate hydratase activity
FOB21_11705	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FOB21_11735	COG0583	DNA-binding transcription factor activity
FOB21_11740	COG4638	Rieske (2fe-2S)
FOB21_11755	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_11760	COG3384	dioxygenase
FOB21_11765	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_11785	COG3011	Protein conserved in bacteria
FOB21_11790	COG0753	catalase activity
FOB21_11830	COG0583	DNA-binding transcription factor activity
FOB21_11840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB21_11855	COG0473	3-isopropylmalate dehydrogenase activity
FOB21_11920	COG1560	Kdo2-lipid A biosynthetic process
FOB21_11960	COG1929	Belongs to the glycerate kinase type-1 family
FOB21_11965	COG0210	DNA helicase
FOB21_11985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB21_11985	COG4651	solute:proton antiporter activity
FOB21_11990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB21_11995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB21_12010	COG0788	formyltetrahydrofolate deformylase activity
FOB21_12050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOB21_12055	COG3040	lipid binding
FOB21_12110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB21_12120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_12120	COG2813	Specifically methylates the guanine in position
FOB21_12125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_12130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB21_12140	COG4774	siderophore transport
FOB21_12155	COG4771	TonB-dependent receptor
FOB21_12165	COG0740	serine-type endopeptidase activity
FOB21_12180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_12180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOB21_12190	COG0280	phosphate acetyltransferase
FOB21_12190	COG0857	belongs to the CobB CobQ family
FOB21_12195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB21_12205	COG2226	methyltransferase
FOB21_12205	COG0596	Alpha beta hydrolase
FOB21_12205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB21_12220	COG0793	Belongs to the peptidase S41A family
FOB21_12230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB21_12245	COG0084	hydrolase, TatD family'
FOB21_12270	COG1162	GTPase activity
FOB21_12275	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB21_12290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB21_12300	COG1538	Outer membrane efflux protein
FOB21_12305	COG1136	(ABC) transporter
FOB21_12305	COG0577	efflux transmembrane transporter activity
FOB21_12310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_12335	COG0028	Belongs to the TPP enzyme family
FOB21_12340	COG0440	acetolactate synthase activity
FOB21_12345	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB21_12380	COG2975	iron-sulfur cluster assembly
FOB21_12400	COG1426	Protein conserved in bacteria
FOB21_12420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_12435	COG0300	oxidoreductase activity
FOB21_12440	COG3956	TIGRFAM MazG family protein
FOB21_12445	COG1555	photosystem II stabilization
FOB21_12450	COG0617	tRNA 3'-terminal CCA addition
FOB21_12455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOB21_12465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB21_12470	COG1660	Displays ATPase and GTPase activities
FOB21_12475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB21_12485	COG2205	protein histidine kinase activity
FOB21_12490	COG0675	Transposase, IS605 OrfB family
FOB21_12495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB21_12550	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB21_12590	COG1960	acyl-CoA dehydrogenase activity
FOB21_12595	COG1960	acyl-CoA dehydrogenase activity
FOB21_12605	COG2205	protein histidine kinase activity
FOB21_12610	COG0745	RESPONSE REGULATOR receiver
FOB21_12620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB21_12635	COG2096	Adenosyltransferase
FOB21_12640	COG4206	TonB-dependent receptor
FOB21_12650	COG0133	tryptophan synthase activity
FOB21_12655	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_12675	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB21_12690	COG0625	glutathione transferase activity
FOB21_12700	COG1238	metal cluster binding
FOB21_12710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB21_12725	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB21_12730	COG0072	phenylalanine-tRNA ligase activity
FOB21_12755	COG0248	Ppx GppA phosphatase
FOB21_12765	COG0037	tRNA processing
FOB21_12810	COG1764	response to oxidative stress
FOB21_12815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB21_12880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB21_12885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB21_12930	COG3293	Transposase
FOB21_12945	COG0494	nUDIX hydrolase
FOB21_12955	COG1214	PFAM Peptidase M22, glycoprotease
FOB21_12960	COG1968	undecaprenyl-diphosphatase activity
FOB21_12995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB21_13005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB21_13015	COG2814	Major facilitator Superfamily
FOB21_13020	COG1012	belongs to the aldehyde dehydrogenase family
FOB21_13020	COG2030	dehydratase
FOB21_13025	COG3396	Phenylacetate-CoA oxygenase
FOB21_13030	COG3460	Phenylacetate-CoA oxygenase
FOB21_13035	COG3396	Phenylacetate-CoA oxygenase
FOB21_13040	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB21_13045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB21_13050	COG1024	Enoyl-CoA hydratase
FOB21_13055	COG1024	Enoyl-CoA hydratase
FOB21_13060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB21_13065	COG0183	Belongs to the thiolase family
FOB21_13070	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOB21_13075	COG3327	negative regulation of DNA-templated transcription, initiation
FOB21_13085	COG4106	trans-aconitate 2-methyltransferase activity
FOB21_13095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB21_13120	COG0730	response to heat
FOB21_13130	COG1196	nuclear chromosome segregation
FOB21_13140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB21_13150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB21_13155	COG2193	ferroxidase activity
FOB21_13195	COG0339	signal peptide processing
FOB21_13220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOB21_13225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOB21_13240	COG0009	L-threonylcarbamoyladenylate synthase
FOB21_13245	COG3101	peptidyl-lysine hydroxylation
FOB21_13250	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB21_13255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOB21_13260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOB21_13265	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_13270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB21_13275	COG1652	LysM domain
FOB21_13280	COG1522	sequence-specific DNA binding
FOB21_13300	COG1113	amino acid transport
FOB21_13320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB21_13335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB21_13345	COG0456	acetyltransferase
FOB21_13355	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB21_13360	COG0492	ferredoxin-NADP+ reductase activity
FOB21_13365	COG1674	ftsk spoiiie
FOB21_13365	COG0531	amino acid
FOB21_13395	COG0204	Acyl-transferase
FOB21_13400	COG2885	chlorophyll binding
FOB21_13405	COG0210	DNA helicase
FOB21_13410	COG0756	dUTP diphosphatase activity
FOB21_13415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB21_13420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB21_13425	COG0121	glutamine amidotransferase
FOB21_13445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_13450	COG0735	belongs to the Fur family
FOB21_13465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB21_13480	COG0420	3'-5' exonuclease activity
FOB21_13490	COG1090	epimerase
FOB21_13495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB21_13505	COG2050	protein possibly involved in aromatic compounds catabolism
FOB21_13510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FOB21_13520	COG0582	viral genome integration into host DNA
FOB21_13535	COG0629	single-stranded DNA binding
FOB21_13570	COG3646	Phage regulatory protein
FOB21_13735	COG4695	Portal protein
FOB21_13750	COG0582	viral genome integration into host DNA
FOB21_13845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOB21_13870	COG1674	ftsk spoiiie
FOB21_13885	COG3177	Filamentation induced by cAMP protein fic
FOB21_13915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB21_13920	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOB21_13925	COG1136	(ABC) transporter
FOB21_13930	COG0783	Belongs to the Dps family
FOB21_13955	COG0500	methyltransferase
FOB21_13965	COG2223	nitrite transmembrane transporter activity
FOB21_13970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FOB21_13980	COG3293	Transposase
FOB21_13990	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FOB21_14020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB21_14030	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB21_14035	COG1077	Cell shape determining protein MreB Mrl
FOB21_14040	COG1792	Involved in formation and maintenance of cell shape
FOB21_14045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOB21_14050	COG0424	maF-like protein
FOB21_14055	COG1530	ribonuclease E activity
FOB21_14070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB21_14105	COG1113	amino acid transport
FOB21_14110	COG2828	Protein conserved in bacteria
FOB21_14115	COG0142	geranyltranstransferase activity
FOB21_14120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_14135	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOB21_14160	COG2323	membrane
FOB21_14195	COG0525	valine-tRNA ligase activity
FOB21_14205	COG1028	Short-chain dehydrogenase reductase Sdr
FOB21_14215	COG2066	Belongs to the glutaminase family
FOB21_14235	COG0306	phosphate transporter
FOB21_14275	COG4771	TonB-dependent receptor
FOB21_14300	COG4181	ATPase activity
FOB21_14305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB21_14330	COG0583	DNA-binding transcription factor activity
FOB21_14335	COG2267	carboxylic ester hydrolase activity
FOB21_14340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB21_14345	COG1773	rubredoxin
FOB21_14350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB21_14370	COG2354	Protein conserved in bacteria
FOB21_14375	COG2321	neutral zinc metallopeptidase
FOB21_14395	COG0589	response to stress
FOB21_14425	COG2009	succinate dehydrogenase
FOB21_14430	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB21_14435	COG1053	succinate dehydrogenase
FOB21_14440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB21_14455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB21_14470	COG2268	Band 7 protein
FOB21_14495	COG0175	sulfate reduction
FOB21_14510	COG3118	belongs to the thioredoxin family
FOB21_14545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB21_14565	COG1597	lipid kinase activity
FOB21_14625	COG0742	ribosomal rna small subunit methyltransferase
FOB21_14630	COG0768	penicillin binding
FOB21_14655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB21_14660	COG2878	Part of a membrane complex involved in electron transport
FOB21_14665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB21_14675	COG3384	dioxygenase
FOB21_14685	COG2234	aminopeptidase activity
FOB21_14690	COG3385	transposase activity
FOB21_14700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB21_14720	COG1802	Transcriptional regulator
FOB21_14755	COG0006	proline dipeptidase activity
FOB21_14760	COG2155	Conserved Protein
FOB21_14770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_14775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB21_14790	COG3107	peptidoglycan biosynthetic process
FOB21_14825	COG1388	LysM domain
FOB21_14825	COG0741	lytic transglycosylase activity
FOB21_14825	COG1388	LysM domain
FOB21_14825	COG0741	lytic transglycosylase activity
FOB21_14830	COG4166	transmembrane transport
FOB21_14835	COG4174	ABC transporter (Permease)
FOB21_14840	COG4239	(ABC) transporter, permease
FOB21_14880	COG0833	amino acid
FOB21_14905	COG0418	dihydroorotase activity
FOB21_14910	COG4251	negative regulation of phosphorylation
FOB21_14910	COG3706	GGDEF domain
FOB21_14910	COG5001	Diguanylate cyclase
FOB21_14910	COG2203	Gaf domain
FOB21_14925	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOB21_14925	COG1902	pentaerythritol trinitrate reductase activity
FOB21_14940	COG1741	Belongs to the pirin family
FOB21_14955	COG3739	integral membrane protein
FOB21_14970	COG3706	GGDEF domain
FOB21_15000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB21_15005	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB21_15100	COG3385	transposase activity
FOB21_15175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB21_15215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB21_15220	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB21_15225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB21_15235	COG0596	Alpha beta hydrolase
FOB21_15240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB21_15245	COG1335	isochorismatase
FOB21_15250	COG0251	oxidation-reduction process
FOB21_15255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB21_15260	COG2233	PERMEase
FOB21_15265	COG2084	Dehydrogenase
FOB21_15280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB21_15285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB21_15295	COG2175	clavaminate synthase activity
FOB21_15320	COG0556	nucleotide-excision repair
FOB21_15345	COG1733	regulation of RNA biosynthetic process
FOB21_15355	COG3293	Transposase
FOB21_15370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB21_15375	COG0671	phosphoesterase, PA-phosphatase related
FOB21_15385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB21_15390	COG0076	glutamate decarboxylase activity
FOB21_15395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOB21_15400	COG0573	inorganic phosphate transmembrane transporter activity
FOB21_15410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB21_15415	COG0616	signal peptide processing
FOB21_15455	COG0482	sulfurtransferase activity
FOB21_15470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOB21_15475	COG1686	Belongs to the peptidase S11 family
FOB21_15495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOB21_15505	COG0583	DNA-binding transcription factor activity
FOB21_15510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB21_15515	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB21_15520	COG1067	ATP-dependent peptidase activity
FOB21_15540	COG0254	rRNA binding
FOB21_15555	COG1509	lysine 2,3-aminomutase activity
FOB21_15560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB21_15565	COG1966	Carbon starvation protein
FOB21_15570	COG2879	small protein
FOB21_15575	COG0714	Associated with various cellular activities
FOB21_15625	COG0640	Transcriptional regulator
FOB21_15635	COG0798	PFAM Bile acid sodium symporter
FOB21_15640	COG0431	NADPH-dependent FMN reductase
FOB21_15645	COG2072	flavoprotein involved in K transport
FOB21_15650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB21_15660	COG0642	Histidine kinase
FOB21_15665	COG0745	RESPONSE REGULATOR receiver
FOB21_15670	COG4232	protein-disulfide reductase activity
FOB21_15675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB21_15690	COG0640	Transcriptional regulator
FOB21_15720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB21_15725	COG1765	OsmC-like protein
FOB21_15735	COG0667	Aldo Keto reductase
FOB21_15760	COG0540	Belongs to the ATCase OTCase family
FOB21_15775	COG2031	fatty acid transporter
FOB21_15780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB21_15800	COG1024	Enoyl-CoA hydratase
FOB21_15805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB21_15810	COG1960	acyl-CoA dehydrogenase activity
FOB21_15815	COG1309	transcriptional regulator
FOB21_15820	COG0318	PFAM AMP-dependent synthetase and ligase
FOB21_15840	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB21_15845	COG0659	secondary active sulfate transmembrane transporter activity
FOB21_15850	COG0625	glutathione transferase activity
FOB21_15865	COG2363	Small membrane protein
FOB21_15880	COG1278	Cold shock
FOB21_15885	COG0513	Belongs to the DEAD box helicase family
FOB21_15895	COG0778	Nitroreductase
FOB21_15920	COG0167	dihydroorotate dehydrogenase activity
FOB21_15935	COG0501	Belongs to the peptidase M48B family
FOB21_15950	COG4783	chaperone-mediated protein folding
FOB21_15965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB21_15975	COG2203	Gaf domain
FOB21_15975	COG2199	diguanylate cyclase activity
FOB21_16080	COG0612	Peptidase, M16
FOB21_16115	COG3025	triphosphatase activity
FOB21_16130	COG0352	thiamine-phosphate diphosphorylase activity
FOB21_16180	COG1309	transcriptional regulator
FOB21_16235	COG2391	methyltransferase activity
FOB21_16255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB21_16265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB21_16280	COG3335	DDE superfamily endonuclease
FOB21_16300	COG0505	Belongs to the CarA family
FOB21_16310	COG0625	glutathione transferase activity
FOB21_16340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB21_16340	COG0517	IMP dehydrogenase activity
FOB21_16345	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB21_16355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOB21_16360	COG1137	ATPase activity
FOB21_16405	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOB21_16440	COG2011	ABC-type metal ion transport system permease component
FOB21_16445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB21_16450	COG1464	Belongs to the NlpA lipoprotein family
FOB21_16480	COG0151	Belongs to the GarS family
FOB21_16485	COG0138	bifunctional purine biosynthesis protein purh
FOB21_16490	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOB21_16525	COG2814	Major facilitator Superfamily
FOB21_16530	COG2814	Major facilitator Superfamily
FOB21_16545	COG3852	Histidine kinase
FOB21_16565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB21_16570	COG0575	Belongs to the CDS family
FOB21_16585	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB21_16595	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_16600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB21_16605	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB21_16620	COG2137	regulation of response to DNA damage stimulus
FOB21_16625	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOB21_16630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOB21_16635	COG1011	Hydrolase
FOB21_16640	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOB21_16650	COG0268	Binds directly to 16S ribosomal RNA
FOB21_16655	COG0702	epimerase
FOB21_16660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB21_16670	COG2197	response regulator
FOB21_16675	COG4585	Histidine kinase
FOB21_16680	COG2850	peptidyl-arginine hydroxylation
FOB21_16685	COG0424	maF-like protein
FOB21_16710	COG0697	spore germination
FOB21_16720	COG0778	Nitroreductase
FOB21_16765	COG3781	membrane
FOB21_16795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB21_16800	COG1027	Aspartate ammonia-lyase
FOB21_16810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB21_16845	COG0316	Belongs to the HesB IscA family
FOB21_16850	COG0822	iron-sulfur transferase activity
FOB21_16875	COG0776	regulation of translation
FOB21_16880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB21_16900	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOB21_16910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB21_16930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB21_16935	COG0569	domain protein
FOB21_16960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB21_16965	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB21_16985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB21_17020	COG4456	Virulence-associated protein
FOB21_17035	COG0776	regulation of translation
FOB21_17060	COG2431	L-lysine efflux transmembrane transporter activity