locus-tag class description DKC18_000010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) DKC18_000035 ENOG4105C5H ABC transporter DKC18_000045 ENOG4108821 RND type efflux pump DKC18_000050 ENOG4108821 RND type efflux pump DKC18_000060 ENOG4105D74 hydrolase DKC18_000115 ENOG4105C8J )-transporter DKC18_000125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DKC18_000155 ENOG4105C2W permease DKC18_000205 ENOG4105F27 Major Facilitator DKC18_000210 ENOG4105CV8 reductase DKC18_000215 ENOG4105HEI LysR family (Transcriptional regulator DKC18_000255 ENOG4105CEN a g-specific adenine glycosylase DKC18_000280 ENOG4108ZZ3 UPF0260 protein DKC18_000315 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DKC18_000320 ENOG4108RWI nicotinamidase DKC18_000325 ENOG4105C09 Bile acid DKC18_000335 ENOG4105EWC Purine nucleoside phosphorylase DKC18_000355 ENOG4108RXX maleylacetoacetate isomerase DKC18_000365 ENOG4105C85 amino acid DKC18_000375 ENOG4105CKI cobalamin synthesis protein DKC18_000385 ENOG4105CZE histidine utilization repressor DKC18_000390 ENOG41090B9 response to stress DKC18_000410 ENOG4105C85 amino acid DKC18_000430 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 DKC18_000525 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) DKC18_000535 ENOG4108ZAI phosphatidylglycerophosphatase a DKC18_000540 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DKC18_000595 ENOG4105KHC sulfurtransferase DKC18_000645 ENOG4106BRA Membrane DKC18_000660 ENOG4105D9M gamma-glutamylcysteine synthetase DKC18_000720 ENOG4105IPS esterase DKC18_000750 ENOG4105C2W permease DKC18_000755 ENOG41084YZ Hydrolase DKC18_000790 ENOG4105BZU Histidine kinase DKC18_000805 ENOG4105KUZ arsenate reductase DKC18_000810 ENOG4105CGK Exodeoxyribonuclease III DKC18_000860 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) DKC18_000865 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) DKC18_000880 ENOG41063SB peptidase DKC18_000885 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) DKC18_000890 ENOG4107QSN dihydrolipoamide acetyltransferase DKC18_000915 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) DKC18_000950 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DKC18_000980 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) DKC18_001020 ENOG41062QD Membrane DKC18_001025 ENOG4107QN1 sodium solute DKC18_001055 ENOG4108WUH Transcriptional regulator, TetR family DKC18_001095 ENOG4107RDB Major Facilitator DKC18_001120 ENOG4108UUM single-stranded DNA-binding protein DKC18_001135 ENOG4105DZR Type I site-specific deoxyribonuclease DKC18_001175 ENOG4108UMN azlc family DKC18_001195 ENOG4108JPW Aminotransferase DKC18_001200 ENOG4105C26 Dehydrogenase DKC18_001210 ENOG4105CHJ isochorismatase hydrolase DKC18_001265 ENOG4105D94 Major Facilitator Superfamily DKC18_001270 ENOG4106NZI LysR family Transcriptional regulator DKC18_001290 ENOG4105CPC Aldo Keto reductase DKC18_001405 ENOG4105DFS Conserved Protein DKC18_001490 ENOG4105CUV Homoserine Kinase DKC18_001505 ENOG41061CK Antibiotic biosynthesis monooxygenase DKC18_001540 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DKC18_001595 ENOG4105CHH sulfate transporter DKC18_001600 ENOG4105PDP Short chain dehydrogenase DKC18_001615 ENOG4105C5H ABC transporter DKC18_001730 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) DKC18_001810 ENOG4108V0P LemA family DKC18_001815 ENOG4105HA9 of methanol dehydrogenase type DKC18_001845 ENOG4108UQY Iron-storage protein DKC18_001860 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DKC18_001875 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) DKC18_001925 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DKC18_001940 ENOG4107IFA Lipase (EC 3.1.1.3) DKC18_001950 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) DKC18_001965 ENOG4107AQZ Membrane DKC18_001970 ENOG4107AQZ Membrane DKC18_001975 ENOG4108JQ1 Dehydrogenase DKC18_001995 ENOG4105VRH Antibiotic biosynthesis monooxygenase DKC18_002000 ENOG4105NF4 modulator of drug activity DKC18_002020 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DKC18_002070 ENOG4105C8Y Acetylornithine aminotransferase DKC18_002140 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit DKC18_002170 ENOG41067S9 phage shock protein C, PspC DKC18_002180 ENOG4105CSU acyl-Coa dehydrogenase DKC18_002210 ENOG4105ECY inositol monophosphatase DKC18_002225 ENOG4105CY3 ABC transporter, permease DKC18_002235 ENOG4105E3I toluene tolerance DKC18_002245 ENOG4107QUT magnesium and cobalt transport protein CorA DKC18_002250 ENOG4108URH decarboxylase DKC18_002260 ENOG4105MJ2 Competence protein DKC18_002285 ENOG4105C29 acyl-CoA thioesterase DKC18_002290 ENOG4105CK2 sodium dicarboxylate symporter DKC18_002305 ENOG4105KPV Transcriptional regulator DKC18_002310 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DKC18_002325 ENOG4105C28 cystathionine DKC18_002330 ENOG41089BK Glutamine amido-transferase DKC18_002340 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) DKC18_002445 ENOG41067V7 50S ribosomal protein L36 DKC18_002455 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) DKC18_002520 ENOG4105VKU nucleicacid-binding protein DKC18_002525 ENOG4105DGW oligopeptidase A DKC18_002575 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase DKC18_002585 ENOG4108594 Permease of the drug metabolite transporter DKC18_002590 ENOG4107S2Z UPF0761 membrane protein DKC18_002595 ENOG4105CS1 NAD(P)H quinone oxidoreductase DKC18_002625 ENOG4105C9A Phoh family DKC18_002635 ENOG4105E4C Lytic transglycosylase catalytic DKC18_002665 ENOG4105D6S protein involved in catabolism of external DNA DKC18_002670 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DKC18_002715 ENOG4105C1G acyl-Coa dehydrogenase DKC18_002780 ENOG4105KB2 stringent starvation protein b DKC18_002790 ENOG4108UJD 30S ribosomal protein S9 DKC18_002800 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) DKC18_002805 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DKC18_002840 ENOG4107RZC phospholipase d DKC18_002850 ENOG4105UYK outer membrane protein a DKC18_002900 ENOG4107QPB Beta-lactamase domain protein DKC18_002905 ENOG4107U2T alpha beta DKC18_002915 ENOG4105NAU thioesterase Superfamily protein DKC18_002975 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase DKC18_002990 ENOG4105VIE preprotein translocase, subunit YajC DKC18_003025 ENOG4105BZU Histidine kinase DKC18_003105 ENOG4105UGU tonB-dependent Receptor DKC18_003125 ENOG4108VY7 phosphate-starvation-inducible protein PsiE DKC18_003130 ENOG4105CSU acyl-Coa dehydrogenase DKC18_003135 ENOG4105CSU acyl-Coa dehydrogenase DKC18_003150 ENOG4105E3W Two component transcriptional regulator (Winged helix family DKC18_003190 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DKC18_003230 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DKC18_003300 ENOG4105CHU acetyl-coa acetyltransferase DKC18_003305 ENOG4108R6W Transcriptional regulator, ARAC family DKC18_003315 ENOG4105TW1 Carbohydrate-selective porin OprB DKC18_003320 ENOG4105DZG Dehydrogenase DKC18_003325 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) DKC18_003365 ENOG4108IQI permease DKC18_003415 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DKC18_003420 ENOG4108N2Y auxin Efflux DKC18_003430 ENOG4105T95 Thiol disulfide interChange protein DKC18_003445 ENOG4105K78 MarR family Transcriptional regulator DKC18_003450 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DKC18_003455 ENOG4105KWI UPF0339 protein DKC18_003485 ENOG4105M3Z response regulator DKC18_003510 ENOG4105WD1 Membrane DKC18_003515 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein DKC18_003590 ENOG4105BZG amino acid carrier protein DKC18_003595 ENOG4105D78 K07001 NTE family protein DKC18_003630 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DKC18_003640 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DKC18_003645 ENOG4105DFF Rod shape-determining protein mreb DKC18_003650 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DKC18_003690 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein DKC18_003700 ENOG4108X0B nad(p)h dehydrogenase (quinone) DKC18_003705 ENOG4108R6W Transcriptional regulator, ARAC family DKC18_003725 ENOG4105CF7 AraC family transcriptional regulator DKC18_003755 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein DKC18_003760 ENOG4105E09 nadh pyrophosphatase DKC18_003795 ENOG4105D78 K07001 NTE family protein DKC18_003820 ENOG4105XJC Two component transcriptional regulator (Winged helix family DKC18_003825 ENOG4105DHQ Histidine kinase DKC18_003890 ENOG4105K8R UPF0145 protein DKC18_003895 ENOG4105K8R UPF0145 protein DKC18_003910 ENOG4105C1P efflux transporter, rnd family, mfp subunit DKC18_003965 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DKC18_003970 ENOG4105KVH Transcriptional regulator DKC18_003995 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) DKC18_004000 ENOG41084BA UPF0250 protein DKC18_004005 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DKC18_004035 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit DKC18_004040 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein DKC18_004050 ENOG4105E33 succinate dehydrogenase DKC18_004065 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 DKC18_004070 ENOG4105C7S Dehydrogenase DKC18_004085 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DKC18_004095 ENOG4105CKW Inner membrane protein yedI DKC18_004180 ENOG41080TK Universal stress protein DKC18_004185 ENOG4105EQK -acetyltransferase DKC18_004190 ENOG4108UQ8 endoribonuclease L-psp DKC18_004195 ENOG4108IG5 Transcriptional regulator DKC18_004205 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain DKC18_004210 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain DKC18_004225 ENOG4105HBR Rna-binding protein DKC18_004235 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) DKC18_004290 ENOG4105CSH Transporter DKC18_004295 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) DKC18_004300 ENOG4105C6V Glycerol-3-phosphate dehydrogenase DKC18_004315 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DKC18_004435 ENOG4107Y80 Major Facilitator superfamily DKC18_004475 ENOG4105DFP Integrase DKC18_004480 ENOG41080IJ Diacylglycerol kinase DKC18_004490 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase DKC18_004510 ENOG4105E4C Lytic transglycosylase catalytic DKC18_004550 ENOG4105CEY Amp-dependent synthetase and ligase DKC18_004560 ENOG4105YCT UPF0386 protein DKC18_004650 ENOG4105K70 DNA-binding protein DKC18_004740 ENOG4108QUU Morphogenesis Protein DKC18_004860 ENOG4108IND Tetr family transcriptional regulator DKC18_004870 ENOG4107TTQ Alpha beta hydrolase fold DKC18_004880 ENOG4105F6U Short-chain dehydrogenase reductase Sdr DKC18_004890 ENOG4105C1P efflux transporter, rnd family, mfp subunit DKC18_004925 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DKC18_004940 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) DKC18_004950 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DKC18_004960 ENOG4105C85 amino acid DKC18_004985 ENOG4105N14 lysine exporter protein LysE YggA DKC18_004990 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DKC18_004995 ENOG4105BZJ Electron transfer flavoprotein DKC18_005000 ENOG4105C10 Electron transfer flavoprotein DKC18_005010 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) DKC18_005015 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DKC18_005060 ENOG4107KET secretion protein, HlyD family DKC18_005090 ENOG4105D60 lipoprotein releasing system transmembrane protein DKC18_005095 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DKC18_005110 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) DKC18_005115 ENOG4107R6F Alpha Beta Hydrolase Fold protein DKC18_005120 ENOG4108V3E phosphoribosylglycinamide formyltransferase DKC18_005130 ENOG4105C02 permease DKC18_005180 ENOG4105KCK Peptidoglycan-associated lipoprotein DKC18_005205 ENOG4107YD3 Thioesterase DKC18_005235 ENOG4108ETH Formylglycinamide ribotide synthetase DKC18_005255 ENOG4105EGD dinuclear metal center protein, YbgI family DKC18_005260 ENOG4108UKI Enoyl-CoA hydratase DKC18_005280 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen DKC18_005295 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) DKC18_005300 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DKC18_005315 ENOG4107R11 Transcriptional regulator DKC18_005320 ENOG4108IJ6 ABC transporter DKC18_005330 ENOG4108I5D sulfate abc transporter DKC18_005345 ENOG4105YAZ 4-amino-4-deoxychorismate lyase DKC18_005350 ENOG4105HHA aminodeoxychorismate lyase DKC18_005365 ENOG4108IYU L-aspartate oxidase DKC18_005370 ENOG4105C0H protease DKC18_005385 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) DKC18_005405 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DKC18_005420 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) DKC18_005430 ENOG4105EMU Dehydrogenase DKC18_005560 ENOG4107R8N Glycosyl transferase, family 2 DKC18_005590 ENOG4108YZY peptidylprolyl cis-trans isomerase DKC18_005600 ENOG4105DZ1 carboxypeptidase DKC18_005645 ENOG4105CBP Major Facilitator DKC18_005655 ENOG4108ETY sodium dicarboxylate symporter DKC18_005690 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DKC18_005705 ENOG4105D3G Pseudouridine synthase DKC18_005710 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) DKC18_005750 ENOG4108JPW Aminotransferase DKC18_005770 ENOG4107RA9 decarboxylase DKC18_005780 ENOG4105CVA phosphate DKC18_005785 ENOG4105C8U phosphate abc transporter DKC18_005795 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) DKC18_005820 ENOG4107QTF adenylosuccinate lyase DKC18_005845 ENOG4105DZ1 carboxypeptidase DKC18_005870 ENOG4105EJC lysr family transcriptional regulator DKC18_005910 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein DKC18_005915 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) DKC18_005925 ENOG4105VCD cytoplasmic protein DKC18_006030 ENOG4105C2I pirin domain protein DKC18_006075 ENOG4105EUJ GTP cyclohydrolase i DKC18_006095 ENOG4108DG9 Smr protein MutS2 DKC18_006120 ENOG4105DDQ anthranilate synthase DKC18_006135 ENOG4105C5F glutamine synthetase DKC18_006145 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) DKC18_006180 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DKC18_006185 ENOG4107QNR UPF0135 protein DKC18_006200 ENOG4105C6K Malic enzyme DKC18_006245 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DKC18_006250 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) DKC18_006260 ENOG4107RNU major facilitator superfamily MFS_1 DKC18_006270 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DKC18_006315 ENOG4105CVE Lytic murein transglycosylase DKC18_006335 ENOG4105E3A (ABC) transporter DKC18_006340 ENOG4105DA5 (ABC) transporter DKC18_006370 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DKC18_006395 ENOG4105DSP amino acid AbC transporter DKC18_006400 ENOG4106YG3 ABC transporter DKC18_006405 ENOG4108JEH abc transporter atp-binding protein DKC18_006415 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DKC18_006420 ENOG4105CFP Peptidase U32 DKC18_006430 ENOG4105JAB phenazine biosynthesis protein, phzf family DKC18_006455 ENOG4105WXI Bacterial OB fold (BOF) protein DKC18_006485 ENOG4105BZ4 penicillin-binding protein DKC18_006490 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DKC18_006495 ENOG4105VUT cytoplasmic protein DKC18_006500 ENOG4107QYG anthranilate phosphoribosyltransferase DKC18_006515 ENOG4105C1G acyl-Coa dehydrogenase DKC18_006530 ENOG4105CQC Prephenate dehydratase DKC18_006545 ENOG4105E6M Sulphatase-modifying factor protein DKC18_006555 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) DKC18_006580 ENOG4105M08 Membrane DKC18_006585 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) DKC18_006645 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase DKC18_006670 ENOG4105KTH gatB Yqey DKC18_006675 ENOG4105VCC 30S ribosomal protein S21 DKC18_006780 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) DKC18_006810 ENOG4108D32 Methyltransferase DKC18_006840 ENOG4105D6U Sodium Glutamate Symporter DKC18_006850 ENOG4105H9W Short-chain dehydrogenase reductase Sdr DKC18_006910 ENOG4105ENX hydrolase DKC18_006920 ENOG410642W LysR family Transcriptional regulator DKC18_006960 ENOG4105F1S paraquat-inducible protein a DKC18_006965 ENOG4105DY2 Paraquat-inducible protein b DKC18_006975 ENOG4105VT2 5-hydroxyisourate hydrolase DKC18_006990 ENOG4105GR3 Histidine kinase DKC18_007015 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase DKC18_007030 ENOG4105DHQ Histidine kinase DKC18_007035 ENOG4105ETX regulatoR DKC18_007075 ENOG4105CK2 sodium dicarboxylate symporter DKC18_007090 ENOG4108UMI ABC transporter, permease DKC18_007130 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) DKC18_007180 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) DKC18_007185 ENOG4105CDU Replicative dna helicase DKC18_007210 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) DKC18_007220 ENOG4105BZ9 Cytochrome C oxidase, subunit I DKC18_007260 ENOG4105CND Glycosyl transferase, family 2 DKC18_007265 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD DKC18_007275 ENOG4105DEN Luciferase family DKC18_007295 ENOG4105CC0 LysR family Transcriptional regulator DKC18_007320 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DKC18_007350 ENOG4108MEJ flavin reductase domain protein DKC18_007355 ENOG4105D06 uba thif-type nad fad binding protein DKC18_007375 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) DKC18_007385 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) DKC18_007420 ENOG4105CFU surface antigen DKC18_007450 ENOG4105EYW Ion transport protein DKC18_007455 ENOG4105F27 Major Facilitator DKC18_007465 ENOG4105DZ2 Transcriptional regulator DKC18_007515 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DKC18_007520 ENOG4108TZV Membrane DKC18_007550 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DKC18_007560 ENOG4105CPD ethanolamine ammonia-lyase DKC18_007565 ENOG4107R55 ethanolamine transporter DKC18_007575 ENOG4107RR1 TRANSCRIPTIONal DKC18_007585 ENOG4105C0A alcohol dehydrogenase DKC18_007600 ENOG4105F4I Transcriptional regulator DKC18_007620 ENOG4105CD8 aminopeptidase N DKC18_007675 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) DKC18_007745 ENOG4105CUY Mechanosensitive ion channel DKC18_007820 ENOG4105DKK Benzoate DKC18_007825 ENOG4105EW9 transcriptional regulator AsnC family DKC18_007830 ENOG4108NIW Leucine export protein LeuE DKC18_007835 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) DKC18_007840 ENOG4105C5Q Transcriptional regulator DKC18_007855 ENOG4105CHR reductase DKC18_007890 ENOG4107QMP dna polymerase iii subunits gamma and tau DKC18_007915 ENOG4108RWI nicotinamidase DKC18_008010 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase DKC18_008015 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DKC18_008040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DKC18_008050 ENOG4107QZF nitrite reductase NADPH large subunit DKC18_008095 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) DKC18_008100 ENOG4105CVM Molybdenum cofactor synthesis domain protein DKC18_008135 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) DKC18_008140 ENOG4105CMR udp-glucose 4-epimerase DKC18_008230 ENOG4105KNE Phosphatidate cytidylyltransferase DKC18_008245 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DKC18_008265 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DKC18_008280 ENOG4105Y3E Modulates RecA activity (By similarity) DKC18_008290 ENOG4105VEJ Heat shock protein DKC18_008295 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 DKC18_008315 ENOG4105F7P transcriptional regulator AsnC family DKC18_008345 ENOG4108RAV Conserved protein DKC18_008410 ENOG4105CWM branched-chain amino acid transport system II carrier protein DKC18_008415 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) DKC18_008430 ENOG4105M2J Glutaredoxin DKC18_008435 ENOG4105C8Y Acetylornithine aminotransferase DKC18_008440 ENOG4105C2X Arabinose 5-phosphate isomerase DKC18_008465 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) DKC18_008495 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DKC18_008525 ENOG4105E0K tonB-dependent siderophore receptor DKC18_008580 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) DKC18_008595 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) DKC18_008660 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) DKC18_008670 ENOG4107QP7 CoA-transferase subunit A DKC18_008675 ENOG4107QNJ CoA-transferase subunit B DKC18_008685 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase DKC18_008710 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha DKC18_008730 ENOG4105DZG Dehydrogenase DKC18_008740 ENOG4105MD1 YeeE YedE family protein DKC18_008755 ENOG4107HP6 Transcriptional regulator DKC18_008760 ENOG4108PTX LysR family Transcriptional regulator DKC18_008800 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) DKC18_008850 ENOG4105F11 amine oxidase DKC18_008870 ENOG4105CHU acetyl-coa acetyltransferase DKC18_008880 ENOG4107QNJ CoA-transferase subunit B DKC18_008885 ENOG4107QP7 CoA-transferase subunit A DKC18_008895 ENOG4105NN7 muconolactone delta-isomerase DKC18_008900 ENOG4105DTQ mandelate racemase muconate lactonizing DKC18_008905 ENOG4108KB2 LysR family Transcriptional regulator DKC18_008960 ENOG4105NAE bifunctional deaminase-reductase domain protein DKC18_008985 ENOG4107Z3H Transcriptional regulator, TetR family DKC18_009010 ENOG41082JN Transcriptional regulator DKC18_009050 ENOG4105FDP GntR family transcriptional regulator DKC18_009070 ENOG4105CW7 secretion protein, HlyD family DKC18_009085 ENOG4105CZJ Aldehyde dehydrogenase DKC18_009115 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DKC18_009130 ENOG4105E0A ABC, transporter DKC18_009150 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DKC18_009265 ENOG4105EMU Dehydrogenase DKC18_009275 ENOG4105EQ2 LysR family Transcriptional regulator DKC18_009300 ENOG4105E0F Histidine kinase DKC18_009305 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DKC18_009330 ENOG4105X0I Fimbrial DKC18_009390 ENOG4107RZC phospholipase d DKC18_009455 ENOG4105D05 Receptor DKC18_009460 ENOG4105BZS acriflavin resistance protein DKC18_009465 ENOG4105WQI isochorismatase DKC18_009480 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase DKC18_009490 ENOG41085A6 mbth domain-containing protein DKC18_009530 ENOG4105E0C molybdate abc transporter DKC18_009535 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein DKC18_009540 ENOG4105F4R Transcriptional regulator mode DKC18_009580 ENOG4105CHR reductase DKC18_009590 ENOG4105D2S major facilitator superfamily DKC18_009600 ENOG4105DTD Dehydrogenase DKC18_009615 ENOG4105C5X domain protein DKC18_009650 ENOG4108M0I Transcriptional regulator DKC18_009670 ENOG4105CHU acetyl-coa acetyltransferase DKC18_009680 ENOG4107YNJ LysR family Transcriptional regulator DKC18_009700 ENOG4108IJ0 Aspartate ammonia-lyase DKC18_009795 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DKC18_009815 ENOG4105FDP GntR family transcriptional regulator DKC18_009825 ENOG4105UEI Transcriptional Regulator AraC Family DKC18_009855 ENOG4107QPB Beta-lactamase domain protein DKC18_009880 ENOG4105CHR reductase DKC18_009905 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) DKC18_009920 ENOG4105BZU Histidine kinase DKC18_009930 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) DKC18_009935 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DKC18_010040 ENOG4105K59 histidine triad (HIT) protein DKC18_010070 ENOG4107QWP ABC-2 type transporter DKC18_010075 ENOG4105CJ1 ABC, transporter DKC18_010115 ENOG4107TSN permease DKC18_010120 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) DKC18_010130 ENOG4105CHB tonB-dependent Receptor DKC18_010145 ENOG4107TB6 phosphoglycerate mutase DKC18_010155 ENOG4108YZT Adenosylcobinamide kinase DKC18_010175 ENOG4108Z66 YbaK ebsC protein DKC18_010190 ENOG4105C1G acyl-Coa dehydrogenase DKC18_010210 ENOG4105E7U AraC family transcriptional regulator DKC18_010235 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family DKC18_010245 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins DKC18_010250 ENOG4108Z4V iron-sulfur cluster assembly DKC18_010265 ENOG4108ZIT Ferredoxin, 2FE-2S DKC18_010305 ENOG4105K4T epimerase DKC18_010335 ENOG4108JQ6 ABC transporter DKC18_010340 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component DKC18_010375 ENOG4108DNJ Pfam:TonB DKC18_010400 ENOG4107QP3 malate synthase g DKC18_010435 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DKC18_010440 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DKC18_010455 ENOG4108Z6B deaminase DKC18_010480 ENOG4108WWZ General secretion pathway protein J DKC18_010500 ENOG4105F8V Hydrolase, tatD family DKC18_010520 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) DKC18_010545 ENOG4107QJE Chromosome Partitioning Protein DKC18_010555 ENOG4108S0S Nucleotidyl transferase DKC18_010560 ENOG4105EHM Aminoglycoside phosphotransferase DKC18_010565 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) DKC18_010575 ENOG4105D2N Aldolase DKC18_010610 ENOG41080HT Transcriptional regulator, arsr family DKC18_010620 ENOG4105XPP Protein of unknown function (DUF1275) DKC18_010650 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DKC18_010655 ENOG4105CK7 Sodium proline symporter DKC18_010695 ENOG4108YYC ycei family DKC18_010745 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) DKC18_010770 ENOG4105X0I Fimbrial DKC18_010800 ENOG4108IPJ Membrane DKC18_010810 ENOG4105ETS cytosine purines uracil thiamine allantoin DKC18_010840 ENOG41067SE Tetr family transcriptional regulator DKC18_010860 ENOG4105EW9 transcriptional regulator AsnC family DKC18_010870 ENOG4105CDA abc transporter atp-binding protein DKC18_010920 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DKC18_010925 ENOG4108UMI ABC transporter, permease DKC18_010955 ENOG4108UMN azlc family DKC18_010960 ENOG4105ZED uncharacterized protein ygaH DKC18_010995 ENOG4108V06 Glutathione peroxidase DKC18_011010 ENOG4105CK2 sodium dicarboxylate symporter DKC18_011045 ENOG4108JU3 Alkyl hydroperoxide reductase DKC18_011060 ENOG4108KB2 LysR family Transcriptional regulator DKC18_011065 ENOG4105D6J arsenicaL-resistance protein DKC18_011085 ENOG4105CPN adenine deaminase DKC18_011125 ENOG4108IY8 ABC, transporter DKC18_011140 ENOG4105C54 Major Facilitator superfamily DKC18_011170 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DKC18_011215 ENOG41067MG lrgb family DKC18_011220 ENOG4105VAW lrga family DKC18_011230 ENOG4108SHQ Glutathione S-transferase DKC18_011235 ENOG4105CYM Glutathione S-transferase DKC18_011240 ENOG4105CBN LysR family transcriptional regulator DKC18_011265 ENOG4105C9B Cysteine desulfurase DKC18_011275 ENOG4105EXG Transcriptional regulator DKC18_011280 ENOG4105CT1 (ABC) transporter DKC18_011305 ENOG4108HW4 amino acid AbC transporter DKC18_011330 ENOG4105EQ2 LysR family Transcriptional regulator DKC18_011345 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DKC18_011360 ENOG4105EW9 transcriptional regulator AsnC family DKC18_011370 ENOG4105KT5 UmuD protein DKC18_011395 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DKC18_011445 ENOG4105HEI LysR family (Transcriptional regulator DKC18_011475 ENOG4105R8C Transcriptional regulator DKC18_011480 ENOG4105C1G acyl-Coa dehydrogenase DKC18_011490 ENOG4105E39 Enoyl-CoA hydratase DKC18_011530 ENOG4105EQ0 Major Facilitator superfamily DKC18_011545 ENOG4107QP7 CoA-transferase subunit A DKC18_011560 ENOG4105E39 Enoyl-CoA hydratase DKC18_011565 ENOG4108R85 Short chain dehydrogenase DKC18_011575 ENOG4105CHU acetyl-coa acetyltransferase DKC18_011600 ENOG4108UKI Enoyl-CoA hydratase DKC18_011615 ENOG4105C1G acyl-Coa dehydrogenase DKC18_011630 ENOG4107STF Involved in phosphonate degradation (By similarity) DKC18_011660 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase DKC18_011690 ENOG4105ENX hydrolase DKC18_011695 ENOG4105ENX hydrolase DKC18_011700 ENOG4105EQ2 LysR family Transcriptional regulator DKC18_011730 ENOG41082JN Transcriptional regulator DKC18_011750 ENOG4108TGR phosphatase DKC18_011760 ENOG4107YAU phenylacetic acid degradation protein DKC18_011775 ENOG4105DZS Phenylacetate-CoA ligase DKC18_011780 ENOG4105CHU acetyl-coa acetyltransferase DKC18_011795 ENOG4105E39 Enoyl-CoA hydratase DKC18_011800 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DKC18_011805 ENOG4108ZA2 phenylacetate-CoA oxygenase PaaJ subunit DKC18_011810 ENOG4105D9S phenylacetate-CoA oxygenase PaaI subunit DKC18_011815 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit DKC18_011820 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit DKC18_011830 ENOG4105EJQ L-serine dehydratase DKC18_011840 ENOG4105DQ6 Transposase DKC18_011905 ENOG4108WQI RNA Polymerase DKC18_011915 ENOG4105E18 UPF0276 protein DKC18_011930 ENOG4105CHR reductase DKC18_011960 ENOG4105GNX MltA-interacting MipA family protein DKC18_011965 ENOG4105C8Y Acetylornithine aminotransferase DKC18_012010 ENOG4105CNA YD repeat protein DKC18_012050 ENOG4107TXC Transcriptional regulator DKC18_012055 ENOG4105VEQ Cold shock protein DKC18_012060 ENOG41089BK Glutamine amido-transferase DKC18_012065 ENOG4105C28 cystathionine DKC18_012075 ENOG4108XM1 transcriptional regulator AsnC family DKC18_012080 ENOG4105NBK UPF0345 protein DKC18_012095 ENOG41068WN DKC18_012140 ENOG41082JN Transcriptional regulator DKC18_012165 ENOG4105XJC Two component transcriptional regulator (Winged helix family DKC18_012210 ENOG4105CBN LysR family transcriptional regulator DKC18_012225 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr DKC18_012230 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DKC18_012235 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DKC18_012300 ENOG4108IUZ ABC transporter DKC18_012305 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA DKC18_012320 ENOG4105C2X Arabinose 5-phosphate isomerase DKC18_012390 ENOG4105VEQ Cold shock protein DKC18_012425 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DKC18_012490 ENOG4105EUV Phenol 2-monooxygenase DKC18_012510 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein DKC18_012525 ENOG4105FUY alpha subunit DKC18_012530 ENOG4108UKV benzoate 1,2-dioxygenase DKC18_012535 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein DKC18_012540 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase DKC18_012575 ENOG4105D3R alkyl hydroperoxide reductase DKC18_012595 ENOG4108JU3 Alkyl hydroperoxide reductase DKC18_012605 ENOG4108K3A Glutathione S-transferase DKC18_012615 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) DKC18_012620 ENOG4108TGY Glutathione S-transferase DKC18_012630 ENOG4108ZG0 Ompa motb domain protein DKC18_012680 ENOG4108UKZ OsmC family DKC18_012685 ENOG4107RYR Transcriptional regulator, Crp Fnr family DKC18_012690 ENOG4105CPC Aldo Keto reductase DKC18_012745 ENOG4105CPW cytochrome b561 DKC18_012750 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) DKC18_012800 ENOG4105F95 Monooxygenase DKC18_012815 ENOG4107RN6 Monooxygenase DKC18_012875 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DKC18_012920 ENOG4107RGH Aldehyde dehydrogenase DKC18_012925 ENOG4105C85 amino acid DKC18_012965 ENOG4105CUB amino acid DKC18_012985 ENOG4107Y60 (LipO)protein DKC18_012995 ENOG4106B0W Curli production assembly transport component CsgG DKC18_013040 ENOG4105D01 (LipO)protein DKC18_013110 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component DKC18_013125 ENOG4105E9H Lytic Murein transglycosylase DKC18_013125 ENOG4105E9H Lytic Murein transglycosylase DKC18_013130 ENOG4108JDX DNA polymerase iii, epsilon subunit DKC18_013150 ENOG4105W4M Transport-associated protein DKC18_013170 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) DKC18_013175 ENOG4108ZUB Lysine exporter protein (Lyse ygga) DKC18_013195 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family DKC18_013200 ENOG4105D0A hydroxylase DKC18_013275 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DKC18_013285 ENOG4105D82 Glutamate dehydrogenase DKC18_013295 ENOG4105CSM endonuclease III DKC18_013345 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) DKC18_013390 ENOG4107RET Isocitrate lyase DKC18_013400 ENOG4105C37 (CBS) domain DKC18_013420 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) DKC18_013455 ENOG4105VCQ rubredoxin DKC18_013470 ENOG4105C5Q Transcriptional regulator DKC18_013490 ENOG4107U91 Rhomboid family DKC18_013500 ENOG4108I0Y (ABC) transporter DKC18_013505 ENOG4108UJV acyl-CoA thioesterase i DKC18_013525 ENOG4107RNH Outer membrane receptor FepA DKC18_013540 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) DKC18_013565 ENOG4105CJ3 phosphate transporter DKC18_013575 ENOG4105C3R Methionine synthase DKC18_013590 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) DKC18_013595 ENOG4105EU0 Major facilitator Superfamily DKC18_013605 ENOG4105CSV Glutaminase DKC18_013610 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) DKC18_013625 ENOG4105C7K acetolactate synthase DKC18_013655 ENOG4105DJB Major Facilitator Superfamily DKC18_013690 ENOG41069M3 Transcriptional regulator DKC18_013705 ENOG4106YT9 Enoyl-CoA hydratase DKC18_013730 ENOG4108VWS Yaeq family DKC18_013740 ENOG4105CKI cobalamin synthesis protein DKC18_013760 ENOG4105C94 Transporter DKC18_013765 ENOG4105C94 Transporter DKC18_013770 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) DKC18_013800 ENOG4105D5Q Arginine ornithine antiporter DKC18_013825 ENOG4105C0R drug resistance transporter emrb qaca subfamily DKC18_013830 ENOG4105CW7 secretion protein, HlyD family DKC18_013875 ENOG4105EYH Exonuclease DKC18_013890 ENOG4105CZX twitching motility protein DKC18_013895 ENOG4105CZX twitching motility protein DKC18_013900 ENOG41090R7 Ferric uptake DKC18_013910 ENOG4105VDB UPF0125 protein DKC18_013945 ENOG4107QKV phosphomannomutase DKC18_013960 ENOG4108ZG0 Ompa motb domain protein DKC18_013980 ENOG4107QMS site-determining protein DKC18_014000 ENOG4105CNU cell division protein FtsK DKC18_014005 ENOG4105C3M thioredoxin reductase DKC18_014010 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) DKC18_014050 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) DKC18_014065 ENOG4108YXA Membrane DKC18_014070 ENOG4105EUB pirin domain protein DKC18_014080 ENOG4105C4K Nad synthetase DKC18_014115 ENOG4105C94 Transporter DKC18_014145 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DKC18_014170 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DKC18_014175 ENOG4105C34 Pseudouridine synthase DKC18_014180 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DKC18_014200 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) DKC18_014230 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DKC18_014260 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DKC18_014270 ENOG4105DWF phosphomethylpyrimidine kinase DKC18_014275 ENOG4109066 lysm domain bon superfamily protein DKC18_014300 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein DKC18_014310 ENOG4107RTD sua5 ycio yrdc ywlc family protein DKC18_014320 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) DKC18_014325 ENOG4105FE9 pseudouridine synthase DKC18_014335 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) DKC18_014340 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DKC18_014360 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase DKC18_014430 ENOG4107XZC Restriction modification system DNA (Specificity DKC18_014475 ENOG4105HF0 Membrane DKC18_014500 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) DKC18_014555 ENOG4105D1F ATP-binding protein DKC18_014605 ENOG4105K6H D-cysteine desulfhydrase DKC18_014635 ENOG4105DP0 ferredoxin-NADP reductase DKC18_014665 ENOG4105C8S subunit m DKC18_014670 ENOG4105D65 subunit l DKC18_014695 ENOG4107QIZ NADH dehydrogenase DKC18_014700 ENOG4105GKE subunit e DKC18_014730 ENOG4105E0F Histidine kinase DKC18_014735 ENOG4107EXC regulatoR DKC18_014755 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) DKC18_014775 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) DKC18_014795 ENOG4106P55 Transcriptional regulator DKC18_014835 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DKC18_014840 ENOG4107RGD Major Facilitator superfamily DKC18_014875 ENOG4105UMD exodeoxyribonuclease X DKC18_015060 ENOG4108E1C hydrolase DKC18_015145 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DKC18_015150 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DKC18_015180 ENOG4108HCJ Hydrolase DKC18_015185 ENOG4105DJV ribulose-phosphate 3-epimerase DKC18_015210 ENOG41072GX Peptidase M22 Glycoprotease DKC18_015215 ENOG4108Z0R Transferase DKC18_015260 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) DKC18_015265 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) DKC18_015270 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) DKC18_015340 ENOG4105K56 Transcriptional regulator DKC18_015375 ENOG4108VIA integral membrane protein DKC18_015380 ENOG4105II7 pyrroline-5-carboxylate reductase DKC18_015450 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DKC18_015455 ENOG41082NX 50s ribosomal protein l35 DKC18_015470 ENOG4105CYM Glutathione S-transferase DKC18_015485 ENOG4105CEY Amp-dependent synthetase and ligase DKC18_015490 ENOG4105N42 UPF0307 protein DKC18_015495 ENOG41080Z8 PHOSPHOCARRIER protein DKC18_015515 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase DKC18_015525 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein DKC18_015540 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) DKC18_015555 ENOG4105C6T cysteine synthase DKC18_015560 ENOG4105BZU Histidine kinase DKC18_015565 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DKC18_015570 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DKC18_015590 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DKC18_015605 ENOG4106UX7 integral membrane protein DKC18_015645 ENOG4105C3M thioredoxin reductase DKC18_015670 ENOG4105KBH arsR family transcriptional regulator DKC18_015705 ENOG4108IJF Heavy metal efflux pump, CzcA DKC18_015730 ENOG4105E3B Multicopper oxidase DKC18_015745 ENOG4105GR3 Histidine kinase DKC18_015830 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) DKC18_015850 ENOG4105CUZ uba thif-type nad fad binding protein DKC18_015860 ENOG4105F8V Hydrolase, tatD family DKC18_015875 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) DKC18_015905 ENOG4108ZP8 Acetolactate synthase small subunit DKC18_015910 ENOG4105C7K acetolactate synthase DKC18_015940 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) DKC18_015950 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH DKC18_015965 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DKC18_015975 ENOG4105VW4 glutaredoxin 3 DKC18_015995 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) DKC18_016015 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) DKC18_016035 ENOG4105WVQ Fe-S assembly protein IscX DKC18_016080 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family DKC18_016105 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) DKC18_016110 ENOG4108DNC Involved in acetate metabolism (By similarity) DKC18_016115 ENOG4107GFK fumarate DKC18_016135 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DKC18_016155 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DKC18_016165 ENOG4105DWV Homoserine O-trans-acetylase DKC18_016250 ENOG4105SG9 biopolymer transport protein, ExbD DKC18_016280 ENOG4105KDC 50s ribosomal protein l28 DKC18_016310 ENOG4105VFU Rna-binding protein DKC18_016315 ENOG4105C4R Atp-dependent dna helicase DKC18_016340 ENOG4105KVH Transcriptional regulator DKC18_016355 ENOG4105C5H ABC transporter DKC18_016365 ENOG4105N14 lysine exporter protein LysE YggA DKC18_016370 ENOG4105D1S lipid A biosynthesis DKC18_016435 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DKC18_016520 ENOG4105D29 Helix-turn-helix type 11 domain protein DKC18_016530 ENOG4105EI2 Pseudouridine synthase DKC18_016560 ENOG4105CBN LysR family transcriptional regulator DKC18_016570 ENOG4105CSA Coproporphyrinogen iii oxidase DKC18_016580 ENOG4107QI1 Mate efflux family protein DKC18_016630 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) DKC18_016635 ENOG4105C5X domain protein DKC18_016650 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DKC18_016670 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) DKC18_016675 ENOG4108JU5 Magnesium and cobalt efflux protein DKC18_016680 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) DKC18_016715 ENOG4105CKD glutathione-regulated potassium-efflux system protein DKC18_016720 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DKC18_016735 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) DKC18_016795 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DKC18_016805 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) DKC18_016820 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase DKC18_016840 ENOG4108ZE9 Monovalent cation H antiporter subunit C DKC18_016845 ENOG4107R4Z monovalent cation h antiporter subunit d DKC18_016855 ENOG4105W4C monovalent cation H antiporter subunit F DKC18_016860 ENOG4105KJM monovalent cation h antiporter subunit g DKC18_016865 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) DKC18_016875 ENOG4105CHV Transcription elongation factor NusA DKC18_016900 ENOG4107EJC Preprotein translocase subunit SecG DKC18_016925 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DKC18_016935 ENOG4105C2N RNA methyltransferase TrmH family group 3 DKC18_016950 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) DKC18_016960 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DKC18_016990 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DKC18_016995 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DKC18_017045 ENOG4108Z6Z Transcriptional regulator DKC18_017070 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) DKC18_017090 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) DKC18_017140 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DKC18_017145 ENOG4105PM1 preprotein translocase subunit SecE DKC18_017185 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DKC18_017190 ENOG4105TV9 FHA Domain-Containing protein DKC18_017195 ENOG4105GVR general secretion pathway protein D DKC18_017210 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS DKC18_017235 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DKC18_017260 ENOG4108UTW Plays a role in the regulation of phosphate uptake DKC18_017290 ENOG41087AY ADP-Ribose pyrophosphatase DKC18_017300 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters DKC18_017310 ENOG4105CNI cell division protein FtsW DKC18_017345 ENOG4105D6E homoserine dehydrogenase DKC18_017355 ENOG41061WM D-Alanyl-D-Alanine DKC18_017380 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DKC18_017385 ENOG4108K5H permease YjgP YjgQ family protein DKC18_017435 ENOG4105BZU Histidine kinase DKC18_017465 ENOG4108HWY Beta-lactamase DKC18_017490 ENOG4105CHH sulfate transporter DKC18_017535 ENOG4105C0P Mg chelatase subunit ChlI DKC18_017545 ENOG4105FB2 class II Aldolase DKC18_017565 ENOG4105F0N pyrophosphate phospho-hydrolase DKC18_017585 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DKC18_017595 ENOG4105EN6 Membrane DKC18_017600 ENOG4105K5B UPF0225 protein DKC18_017605 ENOG4105EE5 Membrane protein terC DKC18_017610 ENOG4108URH decarboxylase DKC18_017660 ENOG4105CS1 NAD(P)H quinone oxidoreductase DKC18_017710 ENOG4105Y7M Transcriptional regulator, TetR family DKC18_017785 ENOG4108V06 Glutathione peroxidase DKC18_017825 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DKC18_017855 ENOG4105FAV ABC, transporter DKC18_017865 ENOG4105EZR dyp-type peroxidase family protein DKC18_017875 ENOG4107R1I NAD-dependent malic enzyme DKC18_017900 ENOG4105EUB pirin domain protein DKC18_017910 ENOG41090R7 Ferric uptake DKC18_017920 ENOG4108428 Inherit from COG: -acetyltransferase DKC18_017930 ENOG4106MP8 UPF0754 membrane protein DKC18_018035 ENOG4105DFG type I secretion outer membrane protein DKC18_018050 ENOG4105C0D helicase DKC18_018065 ENOG4105DM4 PTS System DKC18_018075 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) DKC18_018080 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein DKC18_018135 ENOG4105E39 Enoyl-CoA hydratase DKC18_018160 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DKC18_018165 ENOG4105C26 Dehydrogenase DKC18_018175 ENOG4105C85 amino acid DKC18_018180 ENOG4105C85 amino acid DKC18_018185 ENOG4105M4H endoribonuclease L-psp DKC18_018200 ENOG4105EW9 transcriptional regulator AsnC family DKC18_018225 ENOG4105D3G Pseudouridine synthase DKC18_018265 ENOG4105CR4 methylisocitrate lyase DKC18_018295 ENOG41073TP transcriptional regulator DKC18_018300 ENOG4105DAA L-lactate DKC18_018315 ENOG4105CMR udp-glucose 4-epimerase DKC18_018325 ENOG4105C6Y Udp-glucose 6-dehydrogenase DKC18_018330 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DKC18_018335 ENOG4105D3Q Sugar transferase DKC18_018375 ENOG4108Z7G MaoC domain protein dehydratase DKC18_018390 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) DKC18_018395 ENOG4105C1B dTDP-glucose 4-6-dehydratase DKC18_018425 ENOG4108V1T peptidylprolyl cis-trans isomerase DKC18_018430 ENOG4105CJR Integral membrane protein (MviN DKC18_018435 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase DKC18_018450 ENOG4105HSS phospholipase C DKC18_018490 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DKC18_018495 ENOG4105UBK short-chain dehydrogenase reductase DKC18_018525 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DKC18_018530 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DKC18_018535 ENOG4108VM9 ABC, transporter DKC18_018545 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DKC18_018555 ENOG4105DTN riboflavin biosynthesis protein ribF DKC18_018570 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase DKC18_018680 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) DKC18_018690 ENOG4105DFU Cell wall formation (By similarity) DKC18_018700 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase DKC18_018715 ENOG4106032 Glutathionylspermidine synthase DKC18_018730 ENOG4108UGV hypoxanthine phosphoribosyltransferase DKC18_018740 ENOG4105T95 Thiol disulfide interChange protein DKC18_018745 ENOG4105PGM cation diffusion facilitator family transporter DKC18_018775 ENOG4105VG0 50S ribosomal protein l34 DKC18_019005 ENOG41066UD Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium DKC18_019100 ENOG4108JA1 polyketide synthase DKC18_019115 ENOG4108PZW LysR family Transcriptional regulator DKC18_019175 ENOG4105XUP Phage derived protein Gp49-like (DUF891)