locus-tag	class	description
DKE47_000010	COG0592	DNA-directed DNA polymerase activity
DKE47_000030	COG0586	Pfam SNARE associated Golgi protein
DKE47_000060	COG0596	Alpha beta hydrolase
DKE47_000070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKE47_000110	COG0733	neurotransmitter:sodium symporter activity
DKE47_000150	COG2233	PERMEase
DKE47_000205	COG0656	L-ascorbic acid biosynthetic process
DKE47_000210	COG0583	DNA-binding transcription factor activity
DKE47_000230	COG1064	alcohol dehydrogenase
DKE47_000235	COG2818	Glycosylase
DKE47_000250	COG1194	a g-specific adenine glycosylase
DKE47_000265	COG5487	UPF0391 membrane protein
DKE47_000270	COG2983	Belongs to the UPF0260 family
DKE47_000275	COG2133	pyrroloquinoline quinone binding
DKE47_000305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE47_000315	COG0385	Bile acid
DKE47_000355	COG1113	amino acid transport
DKE47_000365	COG0523	cobalamin synthesis protein
DKE47_000375	COG2188	Transcriptional regulator
DKE47_000420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKE47_000430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKE47_000440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKE47_000445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DKE47_000545	COG0436	Aminotransferase
DKE47_000550	COG2733	membrane
DKE47_000565	COG2918	glutathione biosynthetic process
DKE47_000590	COG1388	LysM domain
DKE47_000650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_000660	COG2233	PERMEase
DKE47_000665	COG2351	hydroxyisourate hydrolase activity
DKE47_000720	COG0708	Exodeoxyribonuclease III
DKE47_000765	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKE47_000810	COG2119	membrane
DKE47_000860	COG1902	pentaerythritol trinitrate reductase activity
DKE47_000895	COG1522	sequence-specific DNA binding
DKE47_000925	COG3162	membrane
DKE47_000930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE47_000970	COG1309	transcriptional regulator
DKE47_000990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE47_000990	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_000990	COG0351	phosphomethylpyrimidine kinase
DKE47_001000	COG2814	Major facilitator Superfamily
DKE47_001075	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_001085	COG1335	isochorismatase
DKE47_001120	COG2814	Major facilitator Superfamily
DKE47_001125	COG0583	DNA-binding transcription factor activity
DKE47_001165	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_001315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKE47_001355	COG2205	protein histidine kinase activity
DKE47_001360	COG0745	RESPONSE REGULATOR receiver
DKE47_001380	COG4221	oxidoreductase activity
DKE47_001390	COG0028	Belongs to the TPP enzyme family
DKE47_001460	COG0833	amino acid
DKE47_001510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKE47_001590	COG1704	LemA family
DKE47_001595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DKE47_001660	COG0194	GDP metabolic process
DKE47_001705	COG0228	four-way junction DNA binding
DKE47_001710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKE47_001730	COG5380	lipid catabolic process
DKE47_001750	COG5006	permease, DMT superfamily
DKE47_001780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DKE47_001785	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE47_001815	COG0628	permease
DKE47_001965	COG0517	IMP dehydrogenase activity
DKE47_001970	COG1983	PspC domain protein
DKE47_002020	COG1127	ABC transporter
DKE47_002025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DKE47_002035	COG2854	intermembrane phospholipid transfer
DKE47_002055	COG0494	nUDIX hydrolase
DKE47_002060	COG1040	competence protein
DKE47_002085	COG1946	Acyl-CoA thioesterase
DKE47_002105	COG1959	2 iron, 2 sulfur cluster binding
DKE47_002110	COG1017	nitric oxide dioxygenase activity
DKE47_002110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_002135	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKE47_002140	COG0088	Forms part of the polypeptide exit tunnel
DKE47_002240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKE47_002250	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DKE47_002275	COG1960	acyl-CoA dehydrogenase activity
DKE47_002280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DKE47_002310	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DKE47_002320	COG0557	exoribonuclease II activity
DKE47_002365	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKE47_002370	COG2207	Transcriptional regulator
DKE47_002380	COG1295	ribonuclease BN
DKE47_002415	COG1702	phosphate starvation-inducible protein PhoH
DKE47_002455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DKE47_002460	COG1183	phosphatidylcholine synthase activity
DKE47_002575	COG2969	positive regulation of protein catabolic process
DKE47_002585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKE47_002590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKE47_002600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE47_002605	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE47_002640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE47_002700	COG3453	Protein conserved in bacteria
DKE47_002700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_002715	COG1607	acyl-coa hydrolase
DKE47_002750	COG2350	Protein conserved in bacteria
DKE47_002765	COG3781	membrane
DKE47_002780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKE47_002790	COG1862	Preprotein translocase
DKE47_002865	COG3646	Phage regulatory protein
DKE47_002905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE47_003070	COG0784	Response regulator, receiver
DKE47_003070	COG2198	Histidine kinase
DKE47_003070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_003070	COG2205	protein histidine kinase activity
DKE47_003090	COG2194	sulfuric ester hydrolase activity
DKE47_003185	COG1960	acyl-CoA dehydrogenase activity
DKE47_003205	COG0745	RESPONSE REGULATOR receiver
DKE47_003210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DKE47_003285	COG0285	dihydrofolate synthase activity
DKE47_003320	COG0477	Major facilitator Superfamily
DKE47_003335	COG2153	protein acetylation
DKE47_003360	COG2207	Transcriptional regulator
DKE47_003410	COG2885	chlorophyll binding
DKE47_003410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DKE47_003420	COG1690	Belongs to the RtcB family
DKE47_003425	COG0833	amino acid
DKE47_003465	COG2094	Belongs to the DNA glycosylase MPG family
DKE47_003470	COG4772	TonB-dependent receptor
DKE47_003480	COG0679	Auxin Efflux Carrier
DKE47_003510	COG3189	MarR family transcriptional regulator
DKE47_003515	COG2824	Alkylphosphonate utilization operon protein PhnA
DKE47_003560	COG0840	transmembrane signaling receptor activity
DKE47_003590	COG2832	Protein of unknown function (DUF454)
DKE47_003595	COG1376	ErfK ybiS ycfS ynhG family protein
DKE47_003675	COG1115	amino acid carrier protein
DKE47_003685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE47_003720	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE47_003730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE47_003735	COG1077	Cell shape determining protein MreB Mrl
DKE47_003740	COG1792	Involved in formation and maintenance of cell shape
DKE47_003745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DKE47_003750	COG0424	maF-like protein
DKE47_003755	COG1530	ribonuclease E activity
DKE47_003785	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE47_003810	COG2207	Transcriptional regulator
DKE47_003860	COG0142	geranyltranstransferase activity
DKE47_003865	COG2315	Protein conserved in bacteria
DKE47_003910	COG0745	RESPONSE REGULATOR receiver
DKE47_003915	COG0642	Histidine kinase
DKE47_003955	COG0525	valine-tRNA ligase activity
DKE47_003975	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_003985	COG0393	Putative heavy-metal-binding
DKE47_004005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_004040	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DKE47_004060	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKE47_004095	COG2921	Belongs to the UPF0250 family
DKE47_004135	COG2009	succinate dehydrogenase
DKE47_004140	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DKE47_004145	COG1053	succinate dehydrogenase
DKE47_004150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DKE47_004200	COG2321	neutral zinc metallopeptidase
DKE47_004230	COG0589	response to stress
DKE47_004250	COG0505	Belongs to the CarA family
DKE47_004275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE47_004355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKE47_004375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_004380	COG0584	glycerophosphoryl diester phosphodiesterase
DKE47_004400	COG0741	lytic transglycosylase activity
DKE47_004430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKE47_004510	COG1024	Enoyl-CoA hydratase
DKE47_004520	COG0183	Belongs to the thiolase family
DKE47_004525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DKE47_004595	COG3811	Belongs to the UPF0386 family
DKE47_004680	COG0596	Alpha beta hydrolase
DKE47_004680	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE47_004690	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_004695	COG0583	DNA-binding transcription factor activity
DKE47_004705	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_004725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_004730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKE47_004735	COG0778	Nitroreductase
DKE47_004760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKE47_004765	COG3339	Conserved Protein
DKE47_004820	COG1280	lysine exporter protein (LysE YggA)
DKE47_004825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DKE47_004925	COG4591	ABC-type transport system involved in lipoprotein release permease component
DKE47_004930	COG1136	(ABC) transporter
DKE47_004945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DKE47_004945	COG0616	signal peptide processing
DKE47_004955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKE47_004965	COG0628	permease
DKE47_005040	COG0824	Thioesterase
DKE47_005070	COG2814	Major facilitator Superfamily
DKE47_005085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE47_005090	COG1024	Enoyl-CoA hydratase
DKE47_005095	COG1051	belongs to the nudix hydrolase family
DKE47_005095	COG1056	cytidyltransferase-related domain
DKE47_005110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKE47_005125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKE47_005140	COG4625	pathogenesis
DKE47_005160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DKE47_005175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKE47_005240	COG1381	Involved in DNA repair and RecF pathway recombination
DKE47_005245	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DKE47_005255	COG4221	oxidoreductase activity
DKE47_005390	COG1215	transferase activity, transferring glycosyl groups
DKE47_005415	COG1252	NADH dehydrogenase
DKE47_005420	COG1686	Belongs to the peptidase S11 family
DKE47_005435	COG1187	pseudouridine synthase activity
DKE47_005505	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_005580	COG1522	sequence-specific DNA binding
DKE47_005595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKE47_005630	COG3647	Membrane
DKE47_005655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKE47_005660	COG1686	Belongs to the peptidase S11 family
DKE47_005920	COG0582	viral genome integration into host DNA
DKE47_005935	COG0583	DNA-binding transcription factor activity
DKE47_005980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKE47_005990	COG2879	small protein
DKE47_006035	COG1741	Belongs to the pirin family
DKE47_006055	COG3739	integral membrane protein
DKE47_006125	COG0512	Glutamine amidotransferase of anthranilate synthase
DKE47_006445	COG3104	oligopeptide transport
DKE47_006460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DKE47_006495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE47_006525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE47_006530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKE47_006555	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE47_006560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE47_006580	COG0024	Methionine aminopeptidase
DKE47_006625	COG2951	lytic endotransglycosylase activity
DKE47_006645	COG0842	Transport permease protein
DKE47_006650	COG1131	(ABC) transporter
DKE47_006720	COG1538	Outer membrane efflux protein
DKE47_006745	COG4215	(ABC) transporter
DKE47_006765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE47_006780	COG0384	phenazine biosynthesis protein PhzF
DKE47_006790	COG1720	tRNA m6t6A37 methyltransferase activity
DKE47_006805	COG3111	PFAM Bacterial OB fold (BOF) protein
DKE47_006840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE47_006845	COG3139	Protein of unknown function (DUF1315)
DKE47_006865	COG1960	acyl-CoA dehydrogenase activity
DKE47_006885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DKE47_006905	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKE47_006965	COG0778	Nitroreductase
DKE47_007025	COG1610	YqeY-like protein
DKE47_007030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKE47_007080	COG2831	hemolysin activation secretion protein
DKE47_007110	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DKE47_007205	COG2226	methyltransferase
DKE47_007320	COG1073	alpha beta
DKE47_007340	COG0583	DNA-binding transcription factor activity
DKE47_007345	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_007395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DKE47_007395	COG3008	intermembrane lipid transfer
DKE47_007405	COG2351	hydroxyisourate hydrolase activity
DKE47_007460	COG0642	Histidine kinase
DKE47_007500	COG0625	glutathione transferase activity
DKE47_007545	COG2011	ABC-type metal ion transport system permease component
DKE47_007570	COG0138	bifunctional purine biosynthesis protein purh
DKE47_007575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DKE47_007615	COG1305	Transglutaminase-like
DKE47_007655	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE47_007700	COG1215	transferase activity, transferring glycosyl groups
DKE47_007705	COG3658	cytochrome
DKE47_007715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_007755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE47_007760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKE47_007785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_007815	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DKE47_007820	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DKE47_007885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKE47_007890	COG2814	Major facilitator Superfamily
DKE47_007900	COG0583	DNA-binding transcription factor activity
DKE47_007935	COG0802	atpase or kinase
DKE47_007950	COG1923	regulation of RNA biosynthetic process
DKE47_007955	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_007990	COG0519	Catalyzes the synthesis of GMP from XMP
DKE47_007990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE47_008005	COG0531	amino acid
DKE47_008025	COG1454	alcohol dehydrogenase
DKE47_008100	COG1605	Chorismate mutase
DKE47_008150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE47_008155	COG0668	transmembrane transport
DKE47_008210	COG0589	response to stress
DKE47_008240	COG1522	sequence-specific DNA binding
DKE47_008255	COG0583	DNA-binding transcription factor activity
DKE47_008265	COG0183	Belongs to the thiolase family
DKE47_008315	COG0824	Thioesterase
DKE47_008330	COG1335	isochorismatase
DKE47_008445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKE47_008630	COG3755	Protein conserved in bacteria
DKE47_008800	COG0592	DNA-directed DNA polymerase activity
DKE47_008870	COG3293	Transposase
DKE47_008910	COG0511	ligase activity, forming carbon-carbon bonds
DKE47_008935	COG0745	RESPONSE REGULATOR receiver
DKE47_008975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKE47_008990	COG0315	cyclic pyranopterin monophosphate synthase activity
DKE47_008990	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKE47_009030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DKE47_009095	COG2204	response regulator
DKE47_009125	COG0575	Belongs to the CDS family
DKE47_009160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKE47_009175	COG2137	regulation of response to DNA damage stimulus
DKE47_009210	COG1522	sequence-specific DNA binding
DKE47_009220	COG1113	amino acid transport
DKE47_009240	COG2135	peptidase activity
DKE47_009280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE47_009280	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE47_009280	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DKE47_009285	COG1105	Belongs to the carbohydrate kinase PfkB family
DKE47_009320	COG0024	Methionine aminopeptidase
DKE47_009335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DKE47_009340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE47_009345	COG0517	IMP dehydrogenase activity
DKE47_009345	COG0516	GMP reductase activity
DKE47_009375	COG0552	protein localization to endoplasmic reticulum
DKE47_009385	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DKE47_009400	COG4890	Cyd operon protein YbgT
DKE47_009405	COG1294	oxidase, subunit
DKE47_009430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKE47_009460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE47_009490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DKE47_009560	COG2323	membrane
DKE47_009570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKE47_009595	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKE47_009605	COG2271	Major facilitator Superfamily
DKE47_009610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE47_009620	COG3485	protocatechuate 3,4-dioxygenase
DKE47_009665	COG1414	Transcriptional regulator
DKE47_009740	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_009760	COG3733	amine oxidase
DKE47_009770	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_009775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE47_009780	COG0183	Belongs to the thiolase family
DKE47_009805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE47_009810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE47_009820	COG4829	muconolactone delta-isomerase
DKE47_009840	COG2186	Transcriptional regulator
DKE47_009885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DKE47_009895	COG0789	Transcriptional regulator
DKE47_010035	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_010065	COG2084	Dehydrogenase
DKE47_010120	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE47_010270	COG2205	protein histidine kinase activity
DKE47_010280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE47_010310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKE47_010390	COG3539	Fimbrial protein
DKE47_010440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE47_010520	COG3433	isochorismatase activity
DKE47_010520	COG1535	isochorismatase
DKE47_010590	COG0725	ABC transporter, periplasmic molybdate-binding protein
DKE47_010605	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE47_010610	COG0543	2 iron, 2 sulfur cluster binding
DKE47_010610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_010625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_010665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_010720	COG0183	Belongs to the thiolase family
DKE47_010725	COG0583	DNA-binding transcription factor activity
DKE47_010780	COG4521	taurine ABC transporter
DKE47_010805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKE47_010840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_010840	COG3453	Protein conserved in bacteria
DKE47_010855	COG1063	alcohol dehydrogenase
DKE47_010865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE47_010870	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE47_010880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE47_010885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE47_010900	COG3706	GGDEF domain
DKE47_010925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE47_011060	COG0842	Transport permease protein
DKE47_011065	COG1131	(ABC) transporter
DKE47_011105	COG0730	response to heat
DKE47_011110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKE47_011140	COG0406	alpha-ribazole phosphatase activity
DKE47_011240	COG0822	iron-sulfur transferase activity
DKE47_011245	COG0316	Belongs to the HesB IscA family
DKE47_011300	COG0702	epimerase
DKE47_011335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE47_011445	COG0776	regulation of translation
DKE47_011510	COG0084	hydrolase, TatD family'
DKE47_011535	COG1132	(ABC) transporter
DKE47_011550	COG1192	Involved in chromosome partitioning
DKE47_011560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKE47_011580	COG0191	fructose-bisphosphate aldolase activity
DKE47_011615	COG0640	Transcriptional regulator
DKE47_011625	COG3619	membrane
DKE47_011630	COG3122	Protein conserved in bacteria
DKE47_011635	COG1132	(ABC) transporter
DKE47_011655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKE47_011660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE47_011680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKE47_011705	COG2353	YceI-like domain
DKE47_011780	COG3539	Fimbrial protein
DKE47_011825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DKE47_011885	COG1522	sequence-specific DNA binding
DKE47_011905	COG0765	amino acid transport
DKE47_011945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKE47_011955	COG0012	GTP binding
DKE47_011980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKE47_012010	COG1280	lysine exporter protein (LysE YggA)
DKE47_012020	COG0386	Belongs to the glutathione peroxidase family
DKE47_012100	COG0640	Transcriptional regulator
DKE47_012145	COG2175	clavaminate synthase activity
DKE47_012200	COG1271	oxidase subunit
DKE47_012205	COG1294	oxidase, subunit
DKE47_012285	COG1346	cytolysis
DKE47_012300	COG0625	glutathione transferase activity
DKE47_012305	COG0625	glutathione transferase activity
DKE47_012310	COG0583	DNA-binding transcription factor activity
DKE47_012335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKE47_012340	COG1280	lysine exporter protein (LysE YggA)
DKE47_012360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_012370	COG0765	amino acid transport
DKE47_012375	COG0765	amino acid transport
DKE47_012440	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_012510	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_012520	COG1309	transcriptional regulator
DKE47_012525	COG1960	acyl-CoA dehydrogenase activity
DKE47_012535	COG1024	Enoyl-CoA hydratase
DKE47_012585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE47_012590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE47_012600	COG1960	acyl-CoA dehydrogenase activity
DKE47_012605	COG1024	Enoyl-CoA hydratase
DKE47_012610	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_012615	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKE47_012620	COG0183	Belongs to the thiolase family
DKE47_012635	COG1280	lysine exporter protein (LysE YggA)
DKE47_012670	COG1960	acyl-CoA dehydrogenase activity
DKE47_012715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_012760	COG1012	belongs to the aldehyde dehydrogenase family
DKE47_012765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_012775	COG2267	carboxylic ester hydrolase activity
DKE47_012795	COG3038	cytochrome b561
DKE47_012805	COG1733	regulation of RNA biosynthetic process
DKE47_012855	COG2050	protein possibly involved in aromatic compounds catabolism
DKE47_012865	COG3327	negative regulation of DNA-templated transcription, initiation
DKE47_012900	COG2151	metal-sulfur cluster biosynthetic enzyme
DKE47_012910	COG3460	Phenylacetate-CoA oxygenase
DKE47_012915	COG3396	Phenylacetate-CoA oxygenase
DKE47_012945	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DKE47_012965	COG0590	tRNA wobble adenosine to inosine editing
DKE47_012970	COG0583	DNA-binding transcription factor activity
DKE47_013115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE47_013125	COG0864	Transcriptional regulator
DKE47_013135	COG1733	regulation of RNA biosynthetic process
DKE47_013160	COG1063	alcohol dehydrogenase
DKE47_013210	COG0038	chloride channel
DKE47_013260	COG3220	belongs to the UPF0276 family
DKE47_013275	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_013305	COG3713	MltA-interacting MipA family protein
DKE47_013310	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE47_013445	COG0789	Transcriptional regulator
DKE47_013460	COG0626	cystathionine gamma-synthase activity
DKE47_013470	COG1522	sequence-specific DNA binding
DKE47_013485	COG4774	siderophore transport
DKE47_013565	COG1028	Short-chain dehydrogenase reductase Sdr
DKE47_013590	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DKE47_013630	COG1538	Outer membrane efflux protein
DKE47_013635	COG1137	ATPase activity
DKE47_013640	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DKE47_013650	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DKE47_013655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DKE47_013655	COG0517	IMP dehydrogenase activity
DKE47_013870	COG5377	YqaJ viral recombinase family
DKE47_013955	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_013990	COG1280	lysine exporter protein (LysE YggA)
DKE47_014105	COG2871	sodium ion transport
DKE47_014125	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE47_014130	COG0543	2 iron, 2 sulfur cluster binding
DKE47_014130	COG0633	Ferredoxin
DKE47_014170	COG0450	alkyl hydroperoxide reductase
DKE47_014190	COG3634	alkyl hydroperoxide reductase activity
DKE47_014210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKE47_014215	COG0625	glutathione transferase activity
DKE47_014225	COG2885	chlorophyll binding
DKE47_014275	COG1765	OsmC-like protein
DKE47_014350	COG2252	PERMEase
DKE47_014365	COG0300	oxidoreductase activity
DKE47_014375	COG1741	Belongs to the pirin family
DKE47_014380	COG1309	transcriptional regulator
DKE47_014450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE47_014470	COG1024	Enoyl-CoA hydratase
DKE47_014515	COG2826	transposase and inactivated derivatives, IS30 family
DKE47_014670	COG3501	Rhs element vgr protein
DKE47_014865	COG0582	viral genome integration into host DNA
DKE47_014930	COG4239	(ABC) transporter, permease
DKE47_014990	COG1279	arginine transmembrane transporter activity
DKE47_015020	COG0006	proline dipeptidase activity
DKE47_015090	COG3384	dioxygenase
DKE47_015110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKE47_015130	COG0768	penicillin binding
DKE47_015135	COG0742	ribosomal rna small subunit methyltransferase
DKE47_015260	COG1773	rubredoxin
DKE47_015265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE47_015275	COG0583	DNA-binding transcription factor activity
DKE47_015355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE47_015375	COG0306	phosphate transporter
DKE47_015415	COG2223	nitrite transmembrane transporter activity
DKE47_015420	COG0662	Cupin 2, conserved barrel domain protein
DKE47_015420	COG2207	Transcriptional regulator
DKE47_015430	COG0242	peptide deformylase activity
DKE47_015510	COG1414	Transcriptional regulator
DKE47_015540	COG1024	Enoyl-CoA hydratase
DKE47_015550	COG1215	transferase activity, transferring glycosyl groups
DKE47_015585	COG1607	acyl-coa hydrolase
DKE47_015605	COG1309	transcriptional regulator
DKE47_015655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE47_015760	COG2050	protein possibly involved in aromatic compounds catabolism
DKE47_015775	COG1090	epimerase
DKE47_015835	COG0735	belongs to the Fur family
DKE47_015845	COG2914	Belongs to the UPF0125 (RnfH) family
DKE47_015895	COG2885	chlorophyll binding
DKE47_015915	COG2894	cell division
DKE47_015940	COG0492	ferredoxin-NADP+ reductase activity
DKE47_015955	COG0456	acetyltransferase
DKE47_015985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKE47_016015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE47_016015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKE47_016055	COG0473	3-isopropylmalate dehydrogenase activity
DKE47_016080	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE47_016135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DKE47_016165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE47_016210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE47_016210	COG0351	phosphomethylpyrimidine kinase
DKE47_016210	COG0352	thiamine-phosphate diphosphorylase activity
DKE47_016215	COG1652	LysM domain
DKE47_016240	COG1399	metal-binding, possibly nucleic acid-binding protein
DKE47_016245	COG3101	peptidyl-lysine hydroxylation
DKE47_016250	COG0009	L-threonylcarbamoyladenylate synthase
DKE47_016255	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKE47_016260	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKE47_016275	COG4106	trans-aconitate 2-methyltransferase activity
DKE47_016295	COG1877	trehalose-phosphatase activity
DKE47_016300	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DKE47_016415	COG0489	protein tyrosine kinase activity
DKE47_016470	COG2081	HI0933 family
DKE47_016530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKE47_016600	COG0745	RESPONSE REGULATOR receiver
DKE47_016620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKE47_016690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE47_016705	COG0583	DNA-binding transcription factor activity
DKE47_016715	COG0583	DNA-binding transcription factor activity
DKE47_016780	COG1063	alcohol dehydrogenase
DKE47_016815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DKE47_016850	COG0561	phosphatase activity
DKE47_016855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE47_016875	COG1214	PFAM Peptidase M22, glycoprotease
DKE47_017015	COG1846	Transcriptional regulator
DKE47_017020	COG1764	response to oxidative stress
DKE47_017070	COG0248	Ppx GppA phosphatase
DKE47_017120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKE47_017125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKE47_017155	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_017160	COG3028	Belongs to the UPF0307 family
DKE47_017165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE47_017195	COG1555	photosystem II stabilization
DKE47_017245	COG3622	Belongs to the hyi family
DKE47_017260	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DKE47_017265	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKE47_017285	COG2814	Major facilitator Superfamily
DKE47_017315	COG0492	ferredoxin-NADP+ reductase activity
DKE47_017335	COG0640	Transcriptional regulator
DKE47_017515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE47_017545	COG0084	hydrolase, TatD family'
DKE47_017560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DKE47_017605	COG1309	transcriptional regulator
DKE47_017635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DKE47_017650	COG3321	synthase
DKE47_017650	COG0604	alcohol dehydrogenase
DKE47_017655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DKE47_017670	COG4221	oxidoreductase activity
DKE47_017840	COG0440	acetolactate synthase activity
DKE47_017900	COG1162	GTPase activity
DKE47_017910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DKE47_017930	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKE47_018015	COG3265	gluconokinase activity
DKE47_018045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE47_018045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DKE47_018065	COG0740	serine-type endopeptidase activity
DKE47_018085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE47_018095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE47_018095	COG2813	Specifically methylates the guanine in position
DKE47_018215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKE47_018245	COG0724	RNA recognition motif
DKE47_018250	COG0210	DNA helicase
DKE47_018280	COG1733	regulation of RNA biosynthetic process
DKE47_018290	COG2900	Belongs to the SlyX family
DKE47_018310	COG1560	Kdo2-lipid A biosynthetic process
DKE47_018375	COG0473	3-isopropylmalate dehydrogenase activity
DKE47_018445	COG0583	DNA-binding transcription factor activity
DKE47_018455	COG0625	glutathione transferase activity
DKE47_018460	COG2378	regulation of single-species biofilm formation
DKE47_018510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKE47_018535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DKE47_018570	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DKE47_018575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE47_018615	COG4535	Mg2 and Co2 transporter CorC
DKE47_018625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE47_018645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKE47_018655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKE47_018670	COG0789	Transcriptional regulator
DKE47_018695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKE47_018730	COG2226	methyltransferase
DKE47_018745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE47_018775	COG1006	Multisubunit Na H antiporter MnhC subunit
DKE47_018790	COG2212	antiporter activity
DKE47_018800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKE47_018860	COG0237	dephospho-CoA kinase activity
DKE47_018895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKE47_018910	COG1289	transmembrane transporter activity
DKE47_018925	COG2169	Transcriptional regulator
DKE47_018925	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE47_018930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKE47_019025	COG2056	Na+-H+ antiporter family
DKE47_019130	COG0546	phosphoglycolate phosphatase activity
DKE47_019135	COG1716	ATPase activity
DKE47_019190	COG3275	phosphorelay sensor kinase activity
DKE47_019235	COG0494	nUDIX hydrolase
DKE47_019245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE47_019250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKE47_019280	COG4974	Belongs to the 'phage' integrase family
DKE47_019295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DKE47_019320	COG0793	Belongs to the peptidase S41A family
DKE47_019330	COG0795	lipopolysaccharide-transporting ATPase activity
DKE47_019380	COG0004	ammonium transporteR
DKE47_019385	COG0347	Belongs to the P(II) protein family
DKE47_019460	COG0640	Transcriptional regulator
DKE47_019470	COG0789	Transcriptional regulator
DKE47_019525	COG0606	chelatase, subunit chli
DKE47_019560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DKE47_019585	COG0477	Major facilitator Superfamily
DKE47_019590	COG2860	membrane
DKE47_019655	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE47_019670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE47_019705	COG1309	transcriptional regulator
DKE47_019740	COG0758	DNA mediated transformation
DKE47_019770	COG0386	Belongs to the glutathione peroxidase family
DKE47_019780	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKE47_019840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKE47_019845	COG1280	lysine exporter protein (LysE YggA)
DKE47_019850	COG2837	iron assimilation
DKE47_019890	COG0735	belongs to the Fur family
DKE47_019900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE47_019905	COG0519	Catalyzes the synthesis of GMP from XMP
DKE47_019905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE47_019910	COG4399	Belongs to the UPF0754 family
DKE47_019910	COG4399	Belongs to the UPF0754 family
DKE47_019915	COG2259	Doxx family
DKE47_019945	COG0271	Belongs to the BolA IbaG family
DKE47_020000	COG0318	PFAM AMP-dependent synthetase and ligase
DKE47_020025	COG1024	Enoyl-CoA hydratase
DKE47_020040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE47_020075	COG0251	oxidation-reduction process
DKE47_020090	COG1522	sequence-specific DNA binding
DKE47_020165	COG1403	HNH endonuclease
DKE47_020195	COG1802	Transcriptional regulator
DKE47_020200	COG1448	Aminotransferase
DKE47_020215	COG2186	Transcriptional regulator
DKE47_020240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE47_020255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKE47_020270	COG0438	transferase activity, transferring glycosyl groups
DKE47_020305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DKE47_020315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DKE47_020320	COG1596	polysaccharide export
DKE47_020345	COG0728	peptidoglycan biosynthetic process
DKE47_020405	COG0546	phosphoglycolate phosphatase activity
DKE47_020435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKE47_020440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE47_020450	COG1116	anion transmembrane transporter activity
DKE47_020460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DKE47_020470	COG0196	riboflavin kinase activity
DKE47_020485	COG1047	Peptidyl-prolyl cis-trans
DKE47_020525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKE47_020610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKE47_020625	COG0861	Integral membrane protein TerC family
DKE47_020635	COG0754	glutathionylspermidine amidase activity
DKE47_020665	COG1230	cation diffusion facilitator family transporter
DKE47_020695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKE47_021450	COG3316	Transposase and inactivated derivatives
DKE47_021515	COG3316	Transposase and inactivated derivatives
DKE47_021580	COG1373	ATPase (AAA superfamily
DKE47_021615	COG3316	Transposase and inactivated derivatives
DKE47_021705	COG2369	cell adhesion
DKE47_021735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE47_021785	COG0582	viral genome integration into host DNA
DKE47_021810	COG1475	DNA binding
DKE47_021815	COG1785	Belongs to the alkaline phosphatase family