locus-tag class description DKE48_000030 ENOG4105DQR SNARE associated Golgi DKE48_000040 ENOG4108821 RND type efflux pump DKE48_000050 ENOG4108821 RND type efflux pump DKE48_000060 ENOG4105D74 hydrolase DKE48_000110 ENOG4105C8J )-transporter DKE48_000120 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B DKE48_000160 ENOG4108IG5 Transcriptional regulator DKE48_000205 ENOG4105CV8 reductase DKE48_000270 ENOG4108ZZ3 UPF0260 protein DKE48_000280 ENOG4105D1H recombination factor protein RarA DKE48_000310 ENOG4108RWI nicotinamidase DKE48_000345 ENOG4108RXX maleylacetoacetate isomerase DKE48_000355 ENOG4105C85 amino acid DKE48_000375 ENOG4105CZE histidine utilization repressor DKE48_000380 ENOG41090B9 response to stress DKE48_000395 ENOG4105C85 amino acid DKE48_000405 ENOG41088SP formiminoglutamate hydrolase DKE48_000425 ENOG4108NIW Leucine export protein LeuE DKE48_000505 ENOG4108ZAI phosphatidylglycerophosphatase a DKE48_000510 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) DKE48_000565 ENOG4105KHC sulfurtransferase DKE48_000590 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DKE48_000610 ENOG4105CHM Aminotransferase DKE48_000615 ENOG4106BRA Membrane DKE48_000675 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) DKE48_000690 ENOG41061H0 Monooxygenase DKE48_000715 ENOG41084YZ Hydrolase DKE48_000770 ENOG4105KUZ arsenate reductase DKE48_000775 ENOG4105CGK Exodeoxyribonuclease III DKE48_000820 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) DKE48_000920 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase DKE48_000930 ENOG4105D64 Mechanosensitive ion channel DKE48_000950 ENOG4108W2Y isochorismatase DKE48_000985 ENOG4105E1V na solute symporter DKE48_000990 ENOG41062QD Membrane DKE48_001030 ENOG4108WUH Transcriptional regulator, TetR family DKE48_001050 ENOG4105DWF phosphomethylpyrimidine kinase DKE48_001060 ENOG4107RDB Major Facilitator DKE48_001065 ENOG4108UUM single-stranded DNA-binding protein DKE48_001075 ENOG4108UMN azlc family DKE48_001115 ENOG4105EUB pirin domain protein DKE48_001165 ENOG4105CPC Aldo Keto reductase DKE48_001200 ENOG4105KVH Transcriptional regulator DKE48_001350 ENOG4107QMH DNA methylase DKE48_001475 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) DKE48_001520 ENOG4105E0F Histidine kinase DKE48_001525 ENOG4105DPZ Two component transcriptional regulator (Winged helix family DKE48_001540 ENOG4105PDP Short chain dehydrogenase DKE48_001650 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein DKE48_001675 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) DKE48_001690 ENOG4105DHI Methyltransferase DKE48_001745 ENOG4105BZ8 glutamate synthase DKE48_001755 ENOG4108V0P LemA family DKE48_001770 ENOG4105KHS type IV fimbrial pilin protein DKE48_001780 ENOG4108YSG O-Antigen polymerase DKE48_001795 ENOG4108UQY Iron-storage protein DKE48_001805 ENOG4105KME endoribonuclease L-psp DKE48_001880 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) DKE48_001900 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) DKE48_001935 ENOG4105CQB FAD linked oxidase domain protein DKE48_001950 ENOG4105VRH Antibiotic biosynthesis monooxygenase DKE48_001955 ENOG4105NF4 modulator of drug activity DKE48_001970 ENOG4105EM2 membrane DKE48_002035 ENOG4105C8Y Acetylornithine aminotransferase DKE48_002135 ENOG41067S9 phage shock protein C, PspC DKE48_002175 ENOG4105ECY inositol monophosphatase DKE48_002185 ENOG4105DHJ ABC, transporter DKE48_002190 ENOG4105CY3 ABC transporter, permease DKE48_002215 ENOG4108URH decarboxylase DKE48_002225 ENOG4105MJ2 Competence protein DKE48_002250 ENOG4105C29 acyl-CoA thioesterase DKE48_002270 ENOG4105KPV Transcriptional regulator DKE48_002275 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) DKE48_002305 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) DKE48_002400 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) DKE48_002405 ENOG41067V7 50S ribosomal protein L36 DKE48_002480 ENOG4105VKU nucleicacid-binding protein DKE48_002535 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase DKE48_002555 ENOG4105CS1 NAD(P)H quinone oxidoreductase DKE48_002595 ENOG4105E4C Lytic transglycosylase catalytic DKE48_002635 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase DKE48_002760 ENOG4105KB2 stringent starvation protein b DKE48_002765 ENOG4107MKT Stringent starvation protein a DKE48_002770 ENOG4108UJD 30S ribosomal protein S9 DKE48_002785 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) DKE48_002830 ENOG4105UYK outer membrane protein a DKE48_002840 ENOG4108WS1 DKE48_002880 ENOG4107QPB Beta-lactamase domain protein DKE48_002895 ENOG4105NAU thioesterase Superfamily protein DKE48_002930 ENOG4105K9H YciI-like protein DKE48_002960 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) DKE48_002970 ENOG4105VIE preprotein translocase, subunit YajC DKE48_003015 ENOG4105CM2 brancheD-chain amino acid aminotransferase DKE48_003025 ENOG4108I6E Sulfatase DKE48_003045 ENOG4105CG5 Glycosyl transferase (Group 1 DKE48_003120 ENOG4105CSU acyl-Coa dehydrogenase DKE48_003140 ENOG4105CNG UPF0061 protein DKE48_003175 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) DKE48_003210 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase DKE48_003245 ENOG4105CSH Transporter DKE48_003285 ENOG4108R6W Transcriptional regulator, ARAC family DKE48_003325 ENOG4105CHU acetyl-coa acetyltransferase DKE48_003340 ENOG4105E0Y RtcB Protein DKE48_003345 ENOG4108IQI permease DKE48_003420 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) DKE48_003435 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA DKE48_003470 ENOG4105M3Z response regulator DKE48_003480 ENOG4105C8Q Methyl-accepting chemotaxis DKE48_003510 ENOG4105WD1 Membrane DKE48_003515 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein DKE48_003645 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) DKE48_003650 ENOG4105DFF Rod shape-determining protein mreb DKE48_003655 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) DKE48_003665 ENOG4108Z03 MAF-like protein DKE48_003680 ENOG4105D8T Acyltransferase DKE48_003690 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein DKE48_003700 ENOG4108X0B nad(p)h dehydrogenase (quinone) DKE48_003760 ENOG4105E09 nadh pyrophosphatase DKE48_003770 ENOG4105C7F AcnD-accessory protein PrpF DKE48_003775 ENOG4105CTB Polyprenyl synthetase DKE48_003780 ENOG4105MSB protein, conserved in bacteria DKE48_003795 ENOG4105D78 K07001 NTE family protein DKE48_003825 ENOG4105XJC Two component transcriptional regulator (Winged helix family DKE48_003895 ENOG4105K8R UPF0145 protein DKE48_003900 ENOG4105K8R UPF0145 protein DKE48_003910 ENOG4105BZS acriflavin resistance protein DKE48_003915 ENOG4105C1P efflux transporter, rnd family, mfp subunit DKE48_003970 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) DKE48_004005 ENOG41084BA UPF0250 protein DKE48_004045 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit DKE48_004050 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein DKE48_004095 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha DKE48_004105 ENOG4105CKW Inner membrane protein yedI DKE48_004110 ENOG4105CGZ zinc metallopeptidase DKE48_004195 ENOG41080TK Universal stress protein DKE48_004205 ENOG4108UQ8 endoribonuclease L-psp DKE48_004470 ENOG4108IND Tetr family transcriptional regulator DKE48_004490 ENOG4105F6U Short-chain dehydrogenase reductase Sdr DKE48_004500 ENOG4105C1P efflux transporter, rnd family, mfp subunit DKE48_004535 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) DKE48_004550 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) DKE48_004560 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) DKE48_004570 ENOG4105C85 amino acid DKE48_004595 ENOG4105N14 lysine exporter protein LysE YggA DKE48_004610 ENOG4105C10 Electron transfer flavoprotein DKE48_004695 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) DKE48_004720 ENOG4108V3E phosphoribosylglycinamide formyltransferase DKE48_004730 ENOG4105C02 permease DKE48_004780 ENOG4105KCK Peptidoglycan-associated lipoprotein DKE48_004795 ENOG4105M8F Biopolymer transport protein exbD tolR DKE48_004805 ENOG4107YD3 Thioesterase DKE48_004840 ENOG4105C2C drug resistance transporter, Bcr CflA DKE48_004860 ENOG4105EGD dinuclear metal center protein, YbgI family DKE48_004865 ENOG4108UKI Enoyl-CoA hydratase DKE48_004905 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) DKE48_004920 ENOG4107R11 Transcriptional regulator DKE48_004925 ENOG4108IJ6 ABC transporter DKE48_004935 ENOG4108I5D sulfate abc transporter DKE48_005010 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) DKE48_005025 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) DKE48_005080 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) DKE48_005185 ENOG4108YZY peptidylprolyl cis-trans isomerase DKE48_005190 ENOG4105CEP NADH dehydrogenase DKE48_005195 ENOG4105DZ1 carboxypeptidase DKE48_005210 ENOG4108R99 pseudouridine synthase DKE48_005245 ENOG4105JAB phenazine biosynthesis protein, phzf family DKE48_005285 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) DKE48_005300 ENOG4105D3G Pseudouridine synthase DKE48_005415 ENOG4107QTF adenylosuccinate lyase DKE48_005435 ENOG4108Z0R Transferase DKE48_005440 ENOG4105DZ1 carboxypeptidase DKE48_005475 ENOG4108K5P (LipO)protein DKE48_005480 ENOG4105EJC lysr family transcriptional regulator DKE48_005535 ENOG4105VCD cytoplasmic protein DKE48_005605 ENOG4105C2I pirin domain protein DKE48_005670 ENOG4108DG9 Smr protein MutS2 DKE48_005695 ENOG4105CD8 aminopeptidase N DKE48_005700 ENOG4105DDQ anthranilate synthase DKE48_005760 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) DKE48_005765 ENOG4107QNR UPF0135 protein DKE48_005795 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) DKE48_005800 ENOG4105SYT Methylenetetrahydrofolate reductase DKE48_005845 ENOG4107RNU major facilitator superfamily MFS_1 DKE48_005925 ENOG4105DA5 (ABC) transporter DKE48_005995 ENOG4105F5P DNA-damage-inducible protein d DKE48_006265 ENOG4105E89 ABC transporter DKE48_006275 ENOG4106YG3 ABC transporter DKE48_006290 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DKE48_006315 ENOG4108R96 Methyltransferase, YaeB family DKE48_006330 ENOG4105WXI Bacterial OB fold (BOF) protein DKE48_006365 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) DKE48_006370 ENOG4105VUT cytoplasmic protein DKE48_006375 ENOG4107QYG anthranilate phosphoribosyltransferase DKE48_006390 ENOG4105C1G acyl-Coa dehydrogenase DKE48_006405 ENOG4105CQC Prephenate dehydratase DKE48_006420 ENOG4105E6M Sulphatase-modifying factor protein DKE48_006470 ENOG4105VEQ Cold shock protein DKE48_006475 ENOG4105C1J atp-dependent rna helicase DKE48_006485 ENOG41069NU Nitroreductase DKE48_006545 ENOG4105KTH gatB Yqey DKE48_006550 ENOG4105VCC 30S ribosomal protein S21 DKE48_006645 ENOG4108UMS Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity) DKE48_006695 ENOG4105EVZ LysR family transcriptional regulator DKE48_006705 ENOG4105C26 Dehydrogenase DKE48_006830 ENOG4105ENX hydrolase DKE48_006850 ENOG4105CF7 AraC family transcriptional regulator DKE48_006870 ENOG4105F1S paraquat-inducible protein a DKE48_006890 ENOG4105VT2 5-hydroxyisourate hydrolase DKE48_006950 ENOG4105ETX regulatoR DKE48_007020 ENOG4105C12 Phosphoribosylglycinamide synthetase DKE48_007030 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) DKE48_007085 ENOG4105CDU Replicative dna helicase DKE48_007110 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) DKE48_007280 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) DKE48_007290 ENOG4105EEX Two component transcriptional regulator (Winged helix family DKE48_007310 ENOG4107S74 Lysophospholipid transporter LplT DKE48_007335 ENOG4107QIJ Aconitate hydratase 2 DKE48_007395 ENOG4105K8N protein family UPF0079, ATPase DKE48_007410 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) DKE48_007445 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) DKE48_007455 ENOG4105CPD ethanolamine ammonia-lyase DKE48_007460 ENOG4107R55 ethanolamine transporter DKE48_007480 ENOG4105C0A alcohol dehydrogenase DKE48_007495 ENOG4105F4I Transcriptional regulator DKE48_007530 ENOG4108D1K outer membrane usher protein DKE48_007560 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) DKE48_007630 ENOG4105CUY Mechanosensitive ion channel DKE48_007710 ENOG4105DKK Benzoate DKE48_007715 ENOG4105EW9 transcriptional regulator AsnC family DKE48_007720 ENOG4108NIW Leucine export protein LeuE DKE48_007730 ENOG4105C5Q Transcriptional regulator DKE48_007745 ENOG4105CHR reductase DKE48_007900 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein DKE48_007920 ENOG4105CK6 Two component transcriptional regulator (Winged helix family DKE48_008010 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) DKE48_008015 ENOG4105CMR udp-glucose 4-epimerase DKE48_008075 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family DKE48_008110 ENOG4105KNE Phosphatidate cytidylyltransferase DKE48_008160 ENOG4105Y3E Modulates RecA activity (By similarity) DKE48_008175 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 DKE48_008205 ENOG4105C85 amino acid DKE48_008225 ENOG4105CHH sulfate transporter DKE48_008320 ENOG4105C8Y Acetylornithine aminotransferase DKE48_008325 ENOG4105C2X Arabinose 5-phosphate isomerase DKE48_008425 ENOG4105CZN Potassium uptake protein DKE48_008465 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) DKE48_008470 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit DKE48_008535 ENOG4107VMU Membrane DKE48_008545 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) DKE48_008555 ENOG4107QP7 CoA-transferase subunit A DKE48_008560 ENOG4107QNJ CoA-transferase subunit B DKE48_008585 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase DKE48_008595 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha DKE48_008605 ENOG4106JPM 3-dehydroshikimate dehydratase DKE48_008675 ENOG4105DNH Major Facilitator DKE48_008705 ENOG4105FUY alpha subunit DKE48_008760 ENOG4107QNJ CoA-transferase subunit B DKE48_008775 ENOG4105NN7 muconolactone delta-isomerase DKE48_008840 ENOG4105NAE bifunctional deaminase-reductase domain protein DKE48_008865 ENOG4107Z3H Transcriptional regulator, TetR family DKE48_009045 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DKE48_009155 ENOG4105EMU Dehydrogenase DKE48_009220 ENOG4105X0I Fimbrial DKE48_009380 ENOG41085A6 mbth domain-containing protein DKE48_009435 ENOG4105F4R Transcriptional regulator mode DKE48_009495 ENOG4105DTD Dehydrogenase DKE48_009630 ENOG4105FDP GntR family transcriptional regulator DKE48_009670 ENOG4107QPB Beta-lactamase domain protein DKE48_009680 ENOG4105FFC UPF0187 protein DKE48_009710 ENOG4107R0V Pyruvate dehydrogenase DKE48_009895 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) DKE48_009920 ENOG4107TSN permease DKE48_010000 ENOG4105C1G acyl-Coa dehydrogenase DKE48_010035 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family DKE48_010050 ENOG4108Z4V iron-sulfur cluster assembly DKE48_010065 ENOG4108ZIT Ferredoxin, 2FE-2S DKE48_010105 ENOG4105K4T epimerase DKE48_010225 ENOG4105DWU Membrane DKE48_010240 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) DKE48_010245 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) DKE48_010330 ENOG4105BZ1 (ABC) transporter DKE48_010350 ENOG4107QJE Chromosome Partitioning Protein DKE48_010365 ENOG4105EHM Aminoglycoside phosphotransferase DKE48_010380 ENOG4105D2N Aldolase DKE48_010400 ENOG4108UHJ MAF-like protein DKE48_010405 ENOG4105EZE Cupin 4 family protein DKE48_010415 ENOG41080HT Transcriptional regulator, arsr family DKE48_010430 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme DKE48_010455 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) DKE48_010465 ENOG4105EW9 transcriptional regulator AsnC family DKE48_010475 ENOG4105YGK Pfam:UPF0157 DKE48_010490 ENOG4108T58 Mg2 transport protein CorA DKE48_010500 ENOG4108YYC ycei family DKE48_010575 ENOG4105X0I Fimbrial DKE48_010610 ENOG4108IPJ Membrane DKE48_010720 ENOG4105D01 (LipO)protein DKE48_010725 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) DKE48_010810 ENOG4105CHM Aminotransferase DKE48_010850 ENOG4108JU3 Alkyl hydroperoxide reductase DKE48_010875 ENOG41082YX Transcriptional regulator, arsr family DKE48_010890 ENOG4105CPN adenine deaminase DKE48_010930 ENOG4108IY8 ABC, transporter DKE48_010945 ENOG4105C54 Major Facilitator superfamily DKE48_010965 ENOG4105C4M (Ubiquinol oxidase) subunit I DKE48_010970 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii DKE48_010980 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family DKE48_011000 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase DKE48_011035 ENOG4105DXI Major Facilitator superfamily DKE48_011055 ENOG41067MG lrgb family DKE48_011080 ENOG4105CBN LysR family transcriptional regulator DKE48_011135 ENOG4105CDA abc transporter atp-binding protein DKE48_011160 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase DKE48_011175 ENOG4105EW9 transcriptional regulator AsnC family DKE48_011210 ENOG4105CYX Short-chain dehydrogenase reductase Sdr DKE48_011260 ENOG4105HEI LysR family (Transcriptional regulator DKE48_011290 ENOG4105C1G acyl-Coa dehydrogenase DKE48_011300 ENOG4105E39 Enoyl-CoA hydratase DKE48_011360 ENOG4107QNJ CoA-transferase subunit B DKE48_011380 ENOG4105E39 Enoyl-CoA hydratase DKE48_011405 ENOG4105EQ0 Major Facilitator superfamily DKE48_011445 ENOG4107STF Involved in phosphonate degradation (By similarity) DKE48_011490 ENOG4105HEI LysR family (Transcriptional regulator DKE48_011495 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase DKE48_011510 ENOG4105ETS cytosine purines uracil thiamine allantoin DKE48_011520 ENOG4105C26 Dehydrogenase DKE48_011555 ENOG4105CPW cytochrome b561 DKE48_011565 ENOG4105KVH Transcriptional regulator DKE48_011600 ENOG4108Z0R Transferase DKE48_011650 ENOG4105N76 Phenylacetate-CoA oxygenase, subunit DKE48_011655 ENOG4105CRS phenylacetate-CoA oxygenase PaaG subunit DKE48_011735 ENOG4108Z4X TRANSCRIPTIONal DKE48_011745 ENOG4105WPN DNA integration recombination invertion protein DKE48_011765 ENOG4107Y2X deaminase DKE48_011770 ENOG4105EMY transcriptional regulator DKE48_011860 ENOG4105MRR Transcriptional regulator (By similarity) DKE48_011895 ENOG4105E2A Dehydrogenase DKE48_011995 ENOG4105E18 UPF0276 protein DKE48_012010 ENOG4105CHR reductase DKE48_012025 ENOG41060GT Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity) DKE48_012040 ENOG4105GNX MltA-interacting MipA family protein DKE48_012160 ENOG4105VEQ Cold shock protein DKE48_012165 ENOG41089BK Glutamine amido-transferase DKE48_012180 ENOG4108XM1 transcriptional regulator AsnC family DKE48_012265 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving DKE48_012375 ENOG4105KF3 Short-chain dehydrogenase reductase Sdr DKE48_012380 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DKE48_012385 ENOG41061TZ Short-chain dehydrogenase reductase Sdr DKE48_012400 ENOG4108Z4U Ferredoxin DKE48_012445 ENOG4108IUZ ABC transporter DKE48_012450 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA DKE48_012460 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase DKE48_012550 ENOG410829K Lysine exporter protein (Lyse ygga) DKE48_012580 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) DKE48_012670 ENOG4108KB2 LysR family Transcriptional regulator DKE48_012680 ENOG4108UKV benzoate 1,2-dioxygenase DKE48_012700 ENOG4105D2S major facilitator superfamily DKE48_012740 ENOG4108JU3 Alkyl hydroperoxide reductase DKE48_012770 ENOG4105D5G Transposase DKE48_012835 ENOG4108UKZ OsmC family DKE48_012840 ENOG4107RYR Transcriptional regulator, Crp Fnr family DKE48_012860 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis DKE48_012870 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase DKE48_012905 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) DKE48_012955 ENOG4105JQZ Methyltransferase DKE48_013005 ENOG4105E3J oxidoreductase DKE48_013020 ENOG4108SC4 )-transporter DKE48_013090 ENOG4105C85 amino acid DKE48_013130 ENOG4105CUB amino acid DKE48_013150 ENOG4107Y60 (LipO)protein DKE48_013160 ENOG4106B0W Curli production assembly transport component CsgG DKE48_013270 ENOG4108JQ5 ABC transporter DKE48_013275 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component DKE48_013360 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family DKE48_013405 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase DKE48_013455 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b DKE48_013525 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) DKE48_013580 ENOG4105C37 (CBS) domain DKE48_013600 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) DKE48_013635 ENOG4105VCQ rubredoxin DKE48_013705 ENOG4107RNH Outer membrane receptor FepA DKE48_013725 ENOG4105E6M Sulphatase-modifying factor protein DKE48_013745 ENOG4105CJ3 phosphate transporter DKE48_013785 ENOG4105FTV AraC Family Transcriptional Regulator DKE48_013790 ENOG4105CSV Glutaminase DKE48_013825 ENOG4105CHR reductase DKE48_013855 ENOG4105CHR reductase DKE48_013875 ENOG41069M3 Transcriptional regulator DKE48_013900 ENOG4106YT9 Enoyl-CoA hydratase DKE48_014020 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) DKE48_014140 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) DKE48_014150 ENOG4105CW7 secretion protein, HlyD family DKE48_014155 ENOG4108VUY thioesterase Superfamily protein DKE48_014160 ENOG4105D52 delta-aminolevulinic acid dehydratase DKE48_014165 ENOG4105MWK D-amino acid dehydrogenase, small subunit DKE48_014205 ENOG4105DFA alanine racemase domain protein DKE48_014215 ENOG4105CZX twitching motility protein DKE48_014220 ENOG41090R7 Ferric uptake DKE48_014230 ENOG4105VDB UPF0125 protein DKE48_014280 ENOG4108ZG0 Ompa motb domain protein DKE48_014335 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) DKE48_014345 ENOG4105KEG ribosomal-protein-alanine acetyltransferase DKE48_014390 ENOG4108YXA Membrane DKE48_014395 ENOG4105EUB pirin domain protein DKE48_014405 ENOG4105C4K Nad synthetase DKE48_014430 ENOG4105C26 Dehydrogenase DKE48_014450 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) DKE48_014475 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding DKE48_014495 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase DKE48_014505 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane DKE48_014525 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) DKE48_014555 ENOG4105C5T Phosphoribosyl pyrophosphate synthase DKE48_014585 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) DKE48_014595 ENOG4105DWF phosphomethylpyrimidine kinase DKE48_014600 ENOG4109066 lysm domain bon superfamily protein DKE48_014625 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein DKE48_014630 ENOG4108BPE -transporting atpase DKE48_014635 ENOG4107RTD sua5 ycio yrdc ywlc family protein DKE48_014650 ENOG4105FE9 pseudouridine synthase DKE48_014665 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) DKE48_014720 ENOG4105HF0 Membrane DKE48_014800 ENOG4105D1F ATP-binding protein DKE48_014885 ENOG4105DP0 ferredoxin-NADP reductase DKE48_014890 ENOG4105DUM transcriptional regulator, lysR family DKE48_014915 ENOG4105C8S subunit m DKE48_014920 ENOG4105D65 subunit l DKE48_014930 ENOG4107UFS subunit j DKE48_014990 ENOG4107EXC regulatoR DKE48_015065 ENOG41082JN Transcriptional regulator DKE48_015075 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) DKE48_015095 ENOG4105CR8 Transcriptional regulator DKE48_015115 ENOG4108KB2 LysR family Transcriptional regulator DKE48_015125 ENOG4107EFR Flavocytochrome c DKE48_015145 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F DKE48_015160 ENOG4105ETT transcriptional Regulator, LysR family DKE48_015195 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) DKE48_015200 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) DKE48_015205 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DKE48_015240 ENOG4105DJV ribulose-phosphate 3-epimerase DKE48_015265 ENOG41072GX Peptidase M22 Glycoprotease DKE48_015270 ENOG4108Z0R Transferase DKE48_015320 ENOG4105CRQ synthase (Component I) DKE48_015335 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) DKE48_015415 ENOG4108ZHJ Organic hydroperoxide resistance protein DKE48_015445 ENOG4108VIA integral membrane protein DKE48_015450 ENOG4105II7 pyrroline-5-carboxylate reductase DKE48_015465 ENOG4105C9X ppx gppa phosphatase DKE48_015475 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) DKE48_015520 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) DKE48_015525 ENOG41082NX 50s ribosomal protein l35 DKE48_015560 ENOG4105N42 UPF0307 protein DKE48_015565 ENOG41080Z8 PHOSPHOCARRIER protein DKE48_015595 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein DKE48_015600 ENOG4105DXN mazG family DKE48_015625 ENOG4105C6T cysteine synthase DKE48_015630 ENOG4105BZU Histidine kinase DKE48_015635 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase DKE48_015640 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DKE48_015665 ENOG4105W8H transhydrogenase (subunit alpha DKE48_015670 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) DKE48_015720 ENOG4105F8V Hydrolase, tatD family DKE48_015770 ENOG4108ZP8 Acetolactate synthase small subunit DKE48_015835 ENOG4105ENJ RND efflux system, outer membrane lipoprotein DKE48_015850 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) DKE48_015855 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) DKE48_015865 ENOG4105VW4 glutaredoxin 3 DKE48_015885 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) DKE48_015890 ENOG4105C2D reductase DKE48_015940 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) DKE48_015965 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) DKE48_016005 ENOG4105WVQ Fe-S assembly protein IscX DKE48_016050 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family DKE48_016055 ENOG4105C6Z Gluconate DKE48_016060 ENOG4108UHU Aldolase DKE48_016100 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) DKE48_016120 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) DKE48_016130 ENOG4105DWV Homoserine O-trans-acetylase DKE48_016220 ENOG4105SG9 biopolymer transport protein, ExbD DKE48_016235 ENOG4105CIY formyltetrahydrofolate deformylase DKE48_016250 ENOG4105KDC 50s ribosomal protein l28 DKE48_016310 ENOG4105KVH Transcriptional regulator DKE48_016320 ENOG41069P5 Protein slyX homolog DKE48_016340 ENOG4105D1S lipid A biosynthesis DKE48_016430 ENOG4105DUM transcriptional regulator, lysR family DKE48_016475 ENOG4107RSM transcriptional regulator DKE48_016500 ENOG4105D29 Helix-turn-helix type 11 domain protein DKE48_016570 ENOG4107T8P acyl-Coa dehydrogenase DKE48_016615 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) DKE48_016620 ENOG4105C5X domain protein DKE48_016635 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) DKE48_016655 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) DKE48_016660 ENOG4108JU5 Magnesium and cobalt efflux protein DKE48_016665 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) DKE48_016705 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) DKE48_016720 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) DKE48_016725 ENOG4107QUT magnesium and cobalt transport protein CorA DKE48_016780 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) DKE48_016820 ENOG4108ZE9 Monovalent cation H antiporter subunit C DKE48_016835 ENOG4105W4C monovalent cation H antiporter subunit F DKE48_016880 ENOG4107EJC Preprotein translocase subunit SecG DKE48_016890 ENOG4107QHF type ii secretion system protein e DKE48_016905 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) DKE48_016915 ENOG4105C2N RNA methyltransferase TrmH family group 3 DKE48_016940 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) DKE48_016970 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) DKE48_016975 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase DKE48_017030 ENOG4105MJ9 esterase DKE48_017035 ENOG4108Z6Z Transcriptional regulator DKE48_017080 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) DKE48_017130 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) DKE48_017175 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DKE48_017200 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS DKE48_017225 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) DKE48_017230 ENOG4108NEV two component transcriptional regulator, LytTR family DKE48_017250 ENOG4108UTW Plays a role in the regulation of phosphate uptake DKE48_017260 ENOG4108RNG Permease of the drug metabolite transporter DKE48_017285 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) DKE48_017290 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters DKE48_017325 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) DKE48_017345 ENOG41061WM D-Alanyl-D-Alanine DKE48_017355 ENOG4107TUY Histidine kinase DKE48_017365 ENOG4105CN1 protease DKE48_017370 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) DKE48_017375 ENOG4108K5H permease YjgP YjgQ family protein DKE48_017520 ENOG4105CE1 Ferrous iron transport protein b DKE48_017545 ENOG4105E3B Multicopper oxidase DKE48_017560 ENOG4105GR3 Histidine kinase DKE48_017610 ENOG4105C0P Mg chelatase subunit ChlI DKE48_017620 ENOG4105FB2 class II Aldolase DKE48_017635 ENOG4105EPF Outer membrane porin DKE48_017665 ENOG41079KZ Major Facilitator Superfamily DKE48_017670 ENOG4105EN6 Membrane DKE48_017675 ENOG4105K5B UPF0225 protein DKE48_017685 ENOG4108URH decarboxylase DKE48_017735 ENOG4105CS1 NAD(P)H quinone oxidoreductase DKE48_017750 ENOG4105C6T cysteine synthase DKE48_017835 ENOG4108IND Tetr family transcriptional regulator DKE48_017860 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) DKE48_017890 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) DKE48_017930 ENOG4105EZR dyp-type peroxidase family protein DKE48_017960 ENOG4105EUB pirin domain protein DKE48_017970 ENOG41090R7 Ferric uptake DKE48_017980 ENOG4108428 Inherit from COG: -acetyltransferase DKE48_018000 ENOG4105DQR SNARE associated Golgi DKE48_018025 ENOG4107PSF BolA-like protein DKE48_018080 ENOG4105E39 Enoyl-CoA hydratase DKE48_018085 ENOG4105E39 Enoyl-CoA hydratase DKE48_018110 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase DKE48_018135 ENOG4105M4H endoribonuclease L-psp DKE48_018150 ENOG4105EW9 transcriptional regulator AsnC family DKE48_018175 ENOG4105D3G Pseudouridine synthase DKE48_018195 ENOG4108IG5 Transcriptional regulator DKE48_018295 ENOG4105BZN citrate synthase DKE48_018305 ENOG4105DRR Transcriptional regulator, GntR family DKE48_018315 ENOG4105CGF Aromatic amino acid aminotransferase DKE48_018330 ENOG41073TP transcriptional regulator DKE48_018355 ENOG4105CMR udp-glucose 4-epimerase DKE48_018370 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase DKE48_018380 ENOG4108RYC glycosyltransferase DKE48_018410 ENOG4107QQG Dehydrogenase DKE48_018415 ENOG4105DAY polysaccharide export protein DKE48_018435 ENOG4108V1T peptidylprolyl cis-trans isomerase DKE48_018455 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase DKE48_018490 ENOG41062JF Transcriptional regulator DKE48_018505 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) DKE48_018540 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) DKE48_018545 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component DKE48_018555 ENOG4108R86 Transcriptional regulator DKE48_018560 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) DKE48_018585 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase DKE48_018625 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) DKE48_018705 ENOG4105DFU Cell wall formation (By similarity) DKE48_018745 ENOG4108UGV hypoxanthine phosphoribosyltransferase DKE48_018755 ENOG4105T95 Thiol disulfide interChange protein DKE48_018790 ENOG4105VG0 50S ribosomal protein l34 DKE48_018850 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) DKE48_018900 ENOG4105MZU cell filamentation protein DKE48_018935 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) DKE48_019135 ENOG4105YES addiction module antidote protein DKE48_019325 ENOG4105I1F Resistance protein DKE48_019420 ENOG4105XUP Phage derived protein Gp49-like (DUF891) DKE48_019450 ENOG4108JA1 polyketide synthase DKE48_019525 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase DKE48_019545 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein DKE48_019675 ENOG4105K63 Thioredoxin