locus-tag	class	description
DKE48_000030	COG0586	Pfam SNARE associated Golgi protein
DKE48_000060	COG0596	Alpha beta hydrolase
DKE48_000110	COG0733	neurotransmitter:sodium symporter activity
DKE48_000205	COG0656	L-ascorbic acid biosynthetic process
DKE48_000270	COG2983	Belongs to the UPF0260 family
DKE48_000280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DKE48_000310	COG1335	isochorismatase
DKE48_000345	COG0625	glutathione transferase activity
DKE48_000355	COG1113	amino acid transport
DKE48_000375	COG2188	Transcriptional regulator
DKE48_000405	COG0010	Belongs to the arginase family
DKE48_000425	COG1280	lysine exporter protein (LysE YggA)
DKE48_000505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKE48_000510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DKE48_000610	COG0436	Aminotransferase
DKE48_000615	COG2733	membrane
DKE48_000690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE48_000715	COG2351	hydroxyisourate hydrolase activity
DKE48_000770	COG1393	Belongs to the ArsC family
DKE48_000775	COG0708	Exodeoxyribonuclease III
DKE48_000820	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKE48_000865	COG2119	membrane
DKE48_000870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE48_000870	COG0426	domain, Protein
DKE48_000920	COG1519	Transferase
DKE48_000925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE48_000930	COG0668	transmembrane transport
DKE48_000950	COG1335	isochorismatase
DKE48_000955	COG1522	sequence-specific DNA binding
DKE48_000985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE48_000990	COG3162	membrane
DKE48_001030	COG1309	transcriptional regulator
DKE48_001050	COG0351	phosphomethylpyrimidine kinase
DKE48_001050	COG0352	thiamine-phosphate diphosphorylase activity
DKE48_001050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE48_001060	COG2814	Major facilitator Superfamily
DKE48_001075	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKE48_001165	COG0667	Aldo Keto reductase
DKE48_001200	COG1733	regulation of RNA biosynthetic process
DKE48_001475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKE48_001520	COG2205	protein histidine kinase activity
DKE48_001525	COG0745	RESPONSE REGULATOR receiver
DKE48_001540	COG4221	oxidoreductase activity
DKE48_001675	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKE48_001690	COG2226	methyltransferase
DKE48_001745	COG0493	'glutamate synthase
DKE48_001755	COG1704	LemA family
DKE48_001770	COG4969	Belongs to the N-Me-Phe pilin family
DKE48_001780	COG3307	-O-antigen
DKE48_001880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKE48_001900	COG5380	lipid catabolic process
DKE48_001935	COG0277	FAD linked oxidase domain protein
DKE48_001950	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DKE48_001955	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE48_001970	COG1289	transmembrane transporter activity
DKE48_002035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE48_002085	COG0583	DNA-binding transcription factor activity
DKE48_002135	COG1983	PspC domain protein
DKE48_002185	COG1127	ABC transporter
DKE48_002190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DKE48_002220	COG0494	nUDIX hydrolase
DKE48_002225	COG1040	competence protein
DKE48_002250	COG1946	Acyl-CoA thioesterase
DKE48_002270	COG1959	2 iron, 2 sulfur cluster binding
DKE48_002275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE48_002275	COG1017	nitric oxide dioxygenase activity
DKE48_002305	COG0088	Forms part of the polypeptide exit tunnel
DKE48_002405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKE48_002445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DKE48_002480	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DKE48_002535	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKE48_002595	COG0739	heme binding
DKE48_002595	COG1196	nuclear chromosome segregation
DKE48_002595	COG0741	lytic transglycosylase activity
DKE48_002635	COG1183	phosphatidylcholine synthase activity
DKE48_002760	COG2969	positive regulation of protein catabolic process
DKE48_002770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKE48_002785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE48_002880	COG3453	Protein conserved in bacteria
DKE48_002880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE48_002895	COG1607	acyl-coa hydrolase
DKE48_002930	COG2350	Protein conserved in bacteria
DKE48_002960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKE48_002970	COG1862	Preprotein translocase
DKE48_003025	COG2194	sulfuric ester hydrolase activity
DKE48_003045	COG0438	transferase activity, transferring glycosyl groups
DKE48_003120	COG1960	acyl-CoA dehydrogenase activity
DKE48_003140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DKE48_003175	COG0133	tryptophan synthase activity
DKE48_003210	COG0285	dihydrofolate synthase activity
DKE48_003245	COG0477	Major facilitator Superfamily
DKE48_003285	COG2207	Transcriptional regulator
DKE48_003325	COG0183	Belongs to the thiolase family
DKE48_003340	COG1690	Belongs to the RtcB family
DKE48_003345	COG0833	amino acid
DKE48_003420	COG0354	folic acid binding
DKE48_003435	COG2824	Alkylphosphonate utilization operon protein PhnA
DKE48_003480	COG0840	transmembrane signaling receptor activity
DKE48_003510	COG2832	Protein of unknown function (DUF454)
DKE48_003515	COG1376	ErfK ybiS ycfS ynhG family protein
DKE48_003645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE48_003650	COG1077	Cell shape determining protein MreB Mrl
DKE48_003655	COG1792	Involved in formation and maintenance of cell shape
DKE48_003665	COG0424	maF-like protein
DKE48_003680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE48_003700	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE48_003760	COG2816	NAD+ diphosphatase activity
DKE48_003775	COG0142	geranyltranstransferase activity
DKE48_003780	COG2315	Protein conserved in bacteria
DKE48_003795	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKE48_003825	COG0745	RESPONSE REGULATOR receiver
DKE48_003895	COG0393	Putative heavy-metal-binding
DKE48_003900	COG0393	Putative heavy-metal-binding
DKE48_003915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE48_003970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKE48_004005	COG2921	Belongs to the UPF0250 family
DKE48_004045	COG2009	succinate dehydrogenase
DKE48_004050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DKE48_004055	COG1053	succinate dehydrogenase
DKE48_004105	COG2354	Protein conserved in bacteria
DKE48_004110	COG2321	neutral zinc metallopeptidase
DKE48_004195	COG0589	response to stress
DKE48_004205	COG0251	oxidation-reduction process
DKE48_004470	COG1309	transcriptional regulator
DKE48_004490	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_004500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE48_004510	COG0778	Nitroreductase
DKE48_004535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKE48_004550	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DKE48_004570	COG1113	amino acid transport
DKE48_004595	COG1280	lysine exporter protein (LysE YggA)
DKE48_004695	COG1136	(ABC) transporter
DKE48_004720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKE48_004730	COG0628	permease
DKE48_004805	COG0824	Thioesterase
DKE48_004840	COG2814	Major facilitator Superfamily
DKE48_004860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE48_004865	COG1024	Enoyl-CoA hydratase
DKE48_004905	COG0602	queuosine metabolic process
DKE48_004915	COG4625	pathogenesis
DKE48_004920	COG0583	DNA-binding transcription factor activity
DKE48_004925	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DKE48_004930	COG4208	sulfate ABC transporter
DKE48_004935	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DKE48_005010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DKE48_005025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DKE48_005080	COG0556	nucleotide-excision repair
DKE48_005190	COG1252	NADH dehydrogenase
DKE48_005195	COG1686	Belongs to the peptidase S11 family
DKE48_005210	COG1187	pseudouridine synthase activity
DKE48_005285	COG0352	thiamine-phosphate diphosphorylase activity
DKE48_005435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKE48_005440	COG1686	Belongs to the peptidase S11 family
DKE48_005480	COG0583	DNA-binding transcription factor activity
DKE48_005535	COG2879	small protein
DKE48_005605	COG1741	Belongs to the pirin family
DKE48_005670	COG2840	Smr protein MutS2
DKE48_005695	COG0308	aminopeptidase N
DKE48_005700	COG0512	Glutamine amidotransferase of anthranilate synthase
DKE48_005760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE48_005765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE48_005795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE48_005800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKE48_005845	COG2223	nitrite transmembrane transporter activity
DKE48_005925	COG1131	(ABC) transporter
DKE48_005995	COG3645	SOS response
DKE48_006275	COG4160	amino acid transport
DKE48_006290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE48_006315	COG1720	tRNA m6t6A37 methyltransferase activity
DKE48_006330	COG3111	PFAM Bacterial OB fold (BOF) protein
DKE48_006365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE48_006370	COG3139	Protein of unknown function (DUF1315)
DKE48_006375	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKE48_006390	COG1960	acyl-CoA dehydrogenase activity
DKE48_006420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE48_006475	COG0513	Belongs to the DEAD box helicase family
DKE48_006485	COG0778	Nitroreductase
DKE48_006545	COG1610	YqeY-like protein
DKE48_006550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKE48_006645	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DKE48_006755	COG3243	poly(R)-hydroxyalkanoic acid synthase
DKE48_006830	COG1073	alpha beta
DKE48_006850	COG2207	Transcriptional regulator
DKE48_006870	COG2995	paraquat-inducible protein a
DKE48_006890	COG2351	hydroxyisourate hydrolase activity
DKE48_006950	COG0745	RESPONSE REGULATOR receiver
DKE48_007020	COG0151	Belongs to the GarS family
DKE48_007030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DKE48_007070	COG1305	Transglutaminase-like
DKE48_007085	COG0305	Participates in initiation and elongation during chromosome replication
DKE48_007110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE48_007280	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DKE48_007290	COG0745	RESPONSE REGULATOR receiver
DKE48_007395	COG0802	atpase or kinase
DKE48_007410	COG1923	regulation of RNA biosynthetic process
DKE48_007445	COG0519	Catalyzes the synthesis of GMP from XMP
DKE48_007445	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE48_007455	COG4303	Ethanolamine ammonia lyase large subunit
DKE48_007460	COG0531	amino acid
DKE48_007480	COG1454	alcohol dehydrogenase
DKE48_007495	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DKE48_007560	COG1605	Chorismate mutase
DKE48_007630	COG0668	transmembrane transport
DKE48_007710	COG3135	benzoate transporter
DKE48_007715	COG1522	sequence-specific DNA binding
DKE48_007730	COG0583	DNA-binding transcription factor activity
DKE48_007820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKE48_007900	COG0511	ligase activity, forming carbon-carbon bonds
DKE48_007920	COG0745	RESPONSE REGULATOR receiver
DKE48_008010	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DKE48_008015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE48_008075	COG2204	response regulator
DKE48_008110	COG0575	Belongs to the CDS family
DKE48_008160	COG2137	regulation of response to DNA damage stimulus
DKE48_008175	COG1011	Hydrolase
DKE48_008205	COG1113	amino acid transport
DKE48_008225	COG0659	secondary active sulfate transmembrane transporter activity
DKE48_008320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE48_008325	COG0517	IMP dehydrogenase activity
DKE48_008325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DKE48_008375	COG4890	Cyd operon protein YbgT
DKE48_008425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DKE48_008465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DKE48_008470	COG0542	response to heat
DKE48_008535	COG2323	membrane
DKE48_008545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKE48_008555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE48_008560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE48_008585	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE48_008595	COG3485	protocatechuate 3,4-dioxygenase
DKE48_008605	COG3420	alginic acid biosynthetic process
DKE48_008675	COG2814	Major facilitator Superfamily
DKE48_008705	COG4638	Rieske (2fe-2S)
DKE48_008725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE48_008760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE48_008775	COG4829	muconolactone delta-isomerase
DKE48_008840	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DKE48_008865	COG1309	transcriptional regulator
DKE48_009045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE48_009155	COG4221	oxidoreductase activity
DKE48_009220	COG3539	Fimbrial protein
DKE48_009380	COG3251	PFAM MbtH domain protein
DKE48_009465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE48_009480	COG0412	Dienelactone hydrolase
DKE48_009495	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_009560	COG0583	DNA-binding transcription factor activity
DKE48_009670	COG3453	Protein conserved in bacteria
DKE48_009670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE48_009680	COG3781	membrane
DKE48_009685	COG1063	alcohol dehydrogenase
DKE48_009710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE48_009755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE48_009895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKE48_009920	COG0730	response to heat
DKE48_010000	COG1960	acyl-CoA dehydrogenase activity
DKE48_010050	COG0316	Belongs to the HesB IscA family
DKE48_010105	COG0702	epimerase
DKE48_010145	COG0601	transmembrane transport
DKE48_010225	COG2431	L-lysine efflux transmembrane transporter activity
DKE48_010240	COG0776	regulation of translation
DKE48_010330	COG1132	(ABC) transporter
DKE48_010350	COG1192	Involved in chromosome partitioning
DKE48_010380	COG0191	fructose-bisphosphate aldolase activity
DKE48_010400	COG0424	maF-like protein
DKE48_010405	COG2850	peptidyl-arginine hydroxylation
DKE48_010415	COG0640	Transcriptional regulator
DKE48_010430	COG3122	Protein conserved in bacteria
DKE48_010455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKE48_010475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKE48_010490	COG3698	Phosphodiester glycosidase
DKE48_010500	COG2353	YceI-like domain
DKE48_010575	COG3539	Fimbrial protein
DKE48_010610	COG0697	spore germination
DKE48_010725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKE48_010810	COG0436	Aminotransferase
DKE48_010850	COG3634	alkyl hydroperoxide reductase activity
DKE48_010875	COG0640	Transcriptional regulator
DKE48_010890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DKE48_010930	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DKE48_010945	COG0477	Major facilitator Superfamily
DKE48_010965	COG1271	oxidase subunit
DKE48_010970	COG1294	oxidase, subunit
DKE48_010980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE48_011000	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DKE48_011035	COG2814	Major facilitator Superfamily
DKE48_011055	COG1346	cytolysis
DKE48_011080	COG0583	DNA-binding transcription factor activity
DKE48_011135	COG1126	abc transporter atp-binding protein
DKE48_011210	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_011260	COG0583	DNA-binding transcription factor activity
DKE48_011290	COG1960	acyl-CoA dehydrogenase activity
DKE48_011300	COG1024	Enoyl-CoA hydratase
DKE48_011360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE48_011380	COG1024	Enoyl-CoA hydratase
DKE48_011405	COG2814	Major facilitator Superfamily
DKE48_011445	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DKE48_011490	COG0583	DNA-binding transcription factor activity
DKE48_011495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE48_011510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DKE48_011520	COG1012	belongs to the aldehyde dehydrogenase family
DKE48_011555	COG3038	cytochrome b561
DKE48_011565	COG1733	regulation of RNA biosynthetic process
DKE48_011650	COG3460	Phenylacetate-CoA oxygenase
DKE48_011655	COG3396	Phenylacetate-CoA oxygenase
DKE48_011735	COG0789	Transcriptional regulator
DKE48_011745	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DKE48_011765	COG0590	tRNA wobble adenosine to inosine editing
DKE48_011770	COG0583	DNA-binding transcription factor activity
DKE48_011860	COG0864	Transcriptional regulator
DKE48_011870	COG1733	regulation of RNA biosynthetic process
DKE48_011895	COG1063	alcohol dehydrogenase
DKE48_011995	COG3220	belongs to the UPF0276 family
DKE48_012010	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_012025	COG2076	Multidrug Resistance protein
DKE48_012040	COG3713	MltA-interacting MipA family protein
DKE48_012160	COG1278	Cold shock
DKE48_012180	COG1522	sequence-specific DNA binding
DKE48_012265	COG0653	protein targeting
DKE48_012375	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_012380	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_012385	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_012400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DKE48_012445	COG1137	ATPase activity
DKE48_012450	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DKE48_012460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DKE48_012550	COG1280	lysine exporter protein (LysE YggA)
DKE48_012580	COG1570	exodeoxyribonuclease VII activity
DKE48_012670	COG0583	DNA-binding transcription factor activity
DKE48_012680	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DKE48_012700	COG2814	Major facilitator Superfamily
DKE48_012740	COG3634	alkyl hydroperoxide reductase activity
DKE48_012770	COG3328	transposase activity
DKE48_012835	COG1765	OsmC-like protein
DKE48_012860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKE48_012905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DKE48_012930	COG1741	Belongs to the pirin family
DKE48_012955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DKE48_013005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE48_013020	COG2814	Major facilitator Superfamily
DKE48_013090	COG1113	amino acid transport
DKE48_013130	COG0531	amino acid
DKE48_013230	COG4251	negative regulation of phosphorylation
DKE48_013230	COG5001	Diguanylate cyclase
DKE48_013230	COG3706	GGDEF domain
DKE48_013230	COG2203	Gaf domain
DKE48_013270	COG4172	Belongs to the ABC transporter superfamily
DKE48_013275	COG4239	(ABC) transporter, permease
DKE48_013360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKE48_013405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DKE48_013455	COG3384	dioxygenase
DKE48_013525	COG0830	nickel cation binding
DKE48_013580	COG1253	flavin adenine dinucleotide binding
DKE48_013635	COG1773	rubredoxin
DKE48_013725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE48_013745	COG0306	phosphate transporter
DKE48_013785	COG0662	Cupin 2, conserved barrel domain protein
DKE48_013785	COG2207	Transcriptional regulator
DKE48_013790	COG2066	Belongs to the glutaminase family
DKE48_013825	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_013855	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_013875	COG1414	Transcriptional regulator
DKE48_013900	COG1024	Enoyl-CoA hydratase
DKE48_013950	COG1607	acyl-coa hydrolase
DKE48_014020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE48_014140	COG0405	Gamma-glutamyltransferase
DKE48_014155	COG2050	protein possibly involved in aromatic compounds catabolism
DKE48_014220	COG0735	belongs to the Fur family
DKE48_014225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKE48_014230	COG2914	Belongs to the UPF0125 (RnfH) family
DKE48_014280	COG2885	chlorophyll binding
DKE48_014335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DKE48_014345	COG0456	acetyltransferase
DKE48_014405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKE48_014405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE48_014430	COG1012	belongs to the aldehyde dehydrogenase family
DKE48_014450	COG0473	3-isopropylmalate dehydrogenase activity
DKE48_014475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKE48_014525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DKE48_014555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE48_014585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE48_014595	COG0351	phosphomethylpyrimidine kinase
DKE48_014595	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE48_014595	COG0352	thiamine-phosphate diphosphorylase activity
DKE48_014600	COG1652	LysM domain
DKE48_014625	COG1399	metal-binding, possibly nucleic acid-binding protein
DKE48_014630	COG3101	peptidyl-lysine hydroxylation
DKE48_014635	COG0009	L-threonylcarbamoyladenylate synthase
DKE48_014720	COG0730	response to heat
DKE48_014800	COG0489	protein tyrosine kinase activity
DKE48_014890	COG0583	DNA-binding transcription factor activity
DKE48_014915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKE48_014920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKE48_014990	COG0745	RESPONSE REGULATOR receiver
DKE48_015065	COG1309	transcriptional regulator
DKE48_015075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE48_015095	COG0583	DNA-binding transcription factor activity
DKE48_015115	COG0583	DNA-binding transcription factor activity
DKE48_015125	COG1053	succinate dehydrogenase
DKE48_015140	COG1309	transcriptional regulator
DKE48_015145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DKE48_015160	COG0583	DNA-binding transcription factor activity
DKE48_015165	COG1063	alcohol dehydrogenase
DKE48_015195	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKE48_015200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DKE48_015205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE48_015240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE48_015265	COG1214	PFAM Peptidase M22, glycoprotease
DKE48_015320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DKE48_015335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DKE48_015400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE48_015415	COG1764	response to oxidative stress
DKE48_015465	COG0248	Ppx GppA phosphatase
DKE48_015520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKE48_015525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKE48_015560	COG3028	Belongs to the UPF0307 family
DKE48_015565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE48_015595	COG1555	photosystem II stabilization
DKE48_015600	COG3956	TIGRFAM MazG family protein
DKE48_015630	COG5002	protein histidine kinase activity
DKE48_015630	COG0784	Response regulator, receiver
DKE48_015630	COG2205	protein histidine kinase activity
DKE48_015635	COG1024	Enoyl-CoA hydratase
DKE48_015640	COG2084	Dehydrogenase
DKE48_015665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKE48_015670	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKE48_015685	COG2814	Major facilitator Superfamily
DKE48_015720	COG0084	hydrolase, TatD family'
DKE48_015770	COG0440	acetolactate synthase activity
DKE48_015835	COG1538	Outer membrane efflux protein
DKE48_015850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DKE48_015855	COG1162	GTPase activity
DKE48_015865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DKE48_015885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKE48_015890	COG1028	Short-chain dehydrogenase reductase Sdr
DKE48_015940	COG1216	Glycosyl transferase, family 2
DKE48_015965	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKE48_016050	COG3265	gluconokinase activity
DKE48_016060	COG0800	Aldolase
DKE48_016100	COG0740	serine-type endopeptidase activity
DKE48_016120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE48_016130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKE48_016130	COG2813	Specifically methylates the guanine in position
DKE48_016235	COG0788	formyltetrahydrofolate deformylase activity
DKE48_016250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKE48_016310	COG1733	regulation of RNA biosynthetic process
DKE48_016320	COG2900	Belongs to the SlyX family
DKE48_016340	COG1560	Kdo2-lipid A biosynthetic process
DKE48_016475	COG0583	DNA-binding transcription factor activity
DKE48_016495	COG0625	glutathione transferase activity
DKE48_016500	COG2378	regulation of single-species biofilm formation
DKE48_016615	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DKE48_016620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE48_016635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKE48_016660	COG4535	Mg2 and Co2 transporter CorC
DKE48_016705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKE48_016720	COG0789	Transcriptional regulator
DKE48_016725	COG0598	Magnesium transport protein CorA
DKE48_016780	COG2226	methyltransferase
DKE48_016820	COG1006	Multisubunit Na H antiporter MnhC subunit
DKE48_016835	COG2212	antiporter activity
DKE48_016905	COG0237	dephospho-CoA kinase activity
DKE48_016915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKE48_016940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKE48_016970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE48_016970	COG2169	Transcriptional regulator
DKE48_016975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKE48_017030	COG3545	Serine hydrolase
DKE48_017080	COG0596	Alpha beta hydrolase
DKE48_017175	COG0546	phosphoglycolate phosphatase activity
DKE48_017225	COG0181	hydroxymethylbilane synthase activity
DKE48_017260	COG0697	spore germination
DKE48_017285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKE48_017290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE48_017325	COG4974	Belongs to the 'phage' integrase family
DKE48_017340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DKE48_017350	COG2197	response regulator
DKE48_017365	COG0793	Belongs to the peptidase S41A family
DKE48_017370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DKE48_017375	COG0795	lipopolysaccharide-transporting ATPase activity
DKE48_017475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DKE48_017545	COG2132	Multicopper oxidase
DKE48_017560	COG2205	protein histidine kinase activity
DKE48_017610	COG0606	chelatase, subunit chli
DKE48_017620	COG0235	Class ii aldolase
DKE48_017665	COG0477	Major facilitator Superfamily
DKE48_017670	COG2860	membrane
DKE48_017735	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE48_017750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE48_017835	COG1309	transcriptional regulator
DKE48_017860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKE48_017925	COG1280	lysine exporter protein (LysE YggA)
DKE48_017930	COG2837	iron assimilation
DKE48_017970	COG0735	belongs to the Fur family
DKE48_017980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE48_018000	COG0586	Pfam SNARE associated Golgi protein
DKE48_018025	COG0271	Belongs to the BolA IbaG family
DKE48_018070	COG3916	Acyl-homoserine-lactone synthase
DKE48_018080	COG1024	Enoyl-CoA hydratase
DKE48_018085	COG1024	Enoyl-CoA hydratase
DKE48_018100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE48_018135	COG0251	oxidation-reduction process
DKE48_018150	COG1522	sequence-specific DNA binding
DKE48_018175	COG0564	pseudouridine synthase activity
DKE48_018195	COG1309	transcriptional regulator
DKE48_018305	COG1802	Transcriptional regulator
DKE48_018315	COG1448	Aminotransferase
DKE48_018330	COG2186	Transcriptional regulator
DKE48_018355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE48_018370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKE48_018380	COG1216	Glycosyl transferase, family 2
DKE48_018400	COG1442	glycosyl transferase family 8
DKE48_018400	COG1216	Glycosyl transferase, family 2
DKE48_018410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DKE48_018415	COG1596	polysaccharide export
DKE48_018505	COG0546	phosphoglycolate phosphatase activity
DKE48_018540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE48_018545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE48_018555	COG1309	transcriptional regulator
DKE48_018560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DKE48_018585	COG1047	Peptidyl-prolyl cis-trans
DKE48_018625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKE48_018705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKE48_018755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DKE48_018790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKE48_018835	COG3316	Transposase and inactivated derivatives
DKE48_018850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKE48_018900	COG2184	nucleotidyltransferase activity
DKE48_018935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKE48_019055	COG2801	Transposase and inactivated derivatives
DKE48_019100	COG2801	Transposase and inactivated derivatives
DKE48_019110	COG3173	Aminoglycoside phosphotransferase
DKE48_019135	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKE48_019215	COG3316	Transposase and inactivated derivatives
DKE48_019230	COG3316	Transposase and inactivated derivatives
DKE48_019310	COG3316	Transposase and inactivated derivatives
DKE48_019325	COG1660	Displays ATPase and GTPase activities
DKE48_019420	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
DKE48_019450	COG0604	alcohol dehydrogenase
DKE48_019450	COG3321	synthase
DKE48_019525	COG1902	pentaerythritol trinitrate reductase activity
DKE48_019545	COG2130	NADP-dependent
DKE48_019625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE48_019675	COG3118	belongs to the thioredoxin family
