locus-tag	class	description
FRD49_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FRD49_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRD49_00030	ENOG4105DQR	SNARE associated Golgi
FRD49_00035	ENOG4105C5H	ABC transporter
FRD49_00040	ENOG4108821	RND type efflux pump
FRD49_00045	ENOG4108821	RND type efflux pump
FRD49_00050	ENOG4108821	RND type efflux pump
FRD49_00060	ENOG4105D74	hydrolase
FRD49_00065	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FRD49_00070	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FRD49_00115	ENOG4105C8J	)-transporter
FRD49_00125	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FRD49_00155	ENOG4105C2W	permease
FRD49_00165	ENOG4108IG5	Transcriptional regulator
FRD49_00170	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FRD49_00205	ENOG4105F27	Major Facilitator
FRD49_00210	ENOG4105CV8	reductase
FRD49_00215	ENOG4105HEI	LysR family (Transcriptional regulator
FRD49_00230	ENOG4105DQ4	alcohol dehydrogenase
FRD49_00235	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FRD49_00250	ENOG4105CEN	a g-specific adenine glycosylase
FRD49_00270	ENOG4108ZZ3	UPF0260 protein
FRD49_00275	ENOG4105D8V	Glucose sorbosone dehydrogenase
FRD49_00280	ENOG4105D1H	recombination factor protein RarA
FRD49_00285	ENOG4105S64	Formate nitrite transporter
FRD49_00305	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRD49_00310	ENOG4108RWI	nicotinamidase
FRD49_00315	ENOG4105C09	Bile acid
FRD49_00320	ENOG4107QI1	Mate efflux family protein
FRD49_00325	ENOG4105EWC	Purine nucleoside phosphorylase
FRD49_00345	ENOG4108RXX	maleylacetoacetate isomerase
FRD49_00355	ENOG4105C85	amino acid
FRD49_00365	ENOG4105CKI	cobalamin synthesis protein
FRD49_00375	ENOG4105CZE	histidine utilization repressor
FRD49_00380	ENOG41090B9	response to stress
FRD49_00395	ENOG4105C85	amino acid
FRD49_00405	ENOG41088SP	formiminoglutamate hydrolase
FRD49_00420	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FRD49_00435	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FRD49_00445	ENOG4108ZAI	phosphatidylglycerophosphatase a
FRD49_00450	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FRD49_00465	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FRD49_00505	ENOG4105KHC	sulfurtransferase
FRD49_00525	ENOG4105BZU	Histidine kinase
FRD49_00530	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRD49_00545	ENOG4107QJQ	Mate efflux family protein
FRD49_00550	ENOG4105CHM	Aminotransferase
FRD49_00555	ENOG4106BRA	Membrane
FRD49_00570	ENOG4105D9M	gamma-glutamylcysteine synthetase
FRD49_00580	ENOG4105CS6	Rhs element vgr protein
FRD49_00645	ENOG4105IPS	esterase
FRD49_00650	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRD49_00655	ENOG4108Z2U	ureidoglycolate hydrolase
FRD49_00665	ENOG41061H0	Monooxygenase
FRD49_00680	ENOG41084YZ	Hydrolase
FRD49_00710	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FRD49_00715	ENOG4105BZU	Histidine kinase
FRD49_00730	ENOG4105KUZ	arsenate reductase
FRD49_00735	ENOG4105CGK	Exodeoxyribonuclease III
FRD49_00755	ENOG4105D7Z	glutathione synthase
FRD49_00780	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FRD49_00785	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FRD49_00790	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FRD49_00805	ENOG41063SB	peptidase
FRD49_00810	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FRD49_00815	ENOG4107QSN	dihydrolipoamide acetyltransferase
FRD49_00840	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FRD49_00855	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FRD49_00875	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_00880	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FRD49_00890	ENOG4105D64	Mechanosensitive ion channel
FRD49_00900	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FRD49_00905	ENOG4108W2Y	isochorismatase
FRD49_00915	ENOG4105FBW	Monooxygenase
FRD49_00920	ENOG4108UZX	fmn reductase
FRD49_00935	ENOG4105BZU	Histidine kinase
FRD49_00940	ENOG41062QD	Membrane
FRD49_00945	ENOG4107QN1	sodium solute
FRD49_00955	ENOG4105C94	Transporter
FRD49_00965	ENOG4105BZU	Histidine kinase
FRD49_00970	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FRD49_00975	ENOG4108WUH	Transcriptional regulator, TetR family
FRD49_00990	ENOG4105RA2	Membrane
FRD49_00995	ENOG4108IXY	short-chain dehydrogenase reductase
FRD49_01005	ENOG4105DWF	phosphomethylpyrimidine kinase
FRD49_01015	ENOG4107RDB	Major Facilitator
FRD49_01040	ENOG4108UUM	single-stranded DNA-binding protein
FRD49_01055	ENOG4105ESI	atpase involved in dna repair
FRD49_01110	ENOG4105DZR	Type I site-specific deoxyribonuclease
FRD49_01130	ENOG4108UUM	single-stranded DNA-binding protein
FRD49_01140	ENOG4108UMN	azlc family
FRD49_01150	ENOG4105C85	amino acid
FRD49_01160	ENOG4108JPW	Aminotransferase
FRD49_01165	ENOG4105C26	Dehydrogenase
FRD49_01175	ENOG4105CHJ	isochorismatase hydrolase
FRD49_01180	ENOG4105EUB	pirin domain protein
FRD49_01210	ENOG4105D94	Major Facilitator Superfamily
FRD49_01215	ENOG4106NZI	LysR family Transcriptional regulator
FRD49_01235	ENOG4105CPC	Aldo Keto reductase
FRD49_01240	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
FRD49_01280	ENOG4105KVH	Transcriptional regulator
FRD49_01290	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FRD49_01315	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FRD49_01320	ENOG4108UQN	AraC family transcriptional regulator
FRD49_01375	ENOG4105CUV	Homoserine Kinase
FRD49_01440	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FRD49_01470	ENOG4105CYC	Transferase
FRD49_01480	ENOG4105E0F	Histidine kinase
FRD49_01485	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FRD49_01490	ENOG4105BZM	domain protein
FRD49_01495	ENOG4105CHH	sulfate transporter
FRD49_01500	ENOG4105PDP	Short chain dehydrogenase
FRD49_01510	ENOG4105C7K	acetolactate synthase
FRD49_01515	ENOG4105C5H	ABC transporter
FRD49_01580	ENOG4108IQI	permease
FRD49_01605	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
FRD49_01620	ENOG4105CJN	penicillin-binding protein
FRD49_01625	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FRD49_01630	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FRD49_01645	ENOG4105DHI	Methyltransferase
FRD49_01650	ENOG4108JQC	penicillin-binding protein 1A
FRD49_01675	ENOG4105E4G	Type IV pilus
FRD49_01695	ENOG4105CBC	glutamate synthase
FRD49_01700	ENOG4105BZ8	glutamate synthase
FRD49_01710	ENOG4108V0P	LemA family
FRD49_01715	ENOG4105HA9	of methanol dehydrogenase type
FRD49_01735	ENOG4108YSG	O-Antigen polymerase
FRD49_01740	ENOG4108UQY	Iron-storage protein
FRD49_01750	ENOG4105KME	endoribonuclease L-psp
FRD49_01755	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FRD49_01770	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FRD49_01805	ENOG4105KHS	type IV fimbrial pilin protein
FRD49_01820	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FRD49_01835	ENOG4107IFA	Lipase (EC 3.1.1.3)
FRD49_01840	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
FRD49_01845	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FRD49_01860	ENOG4107AQZ	Membrane
FRD49_01865	ENOG4107AQZ	Membrane
FRD49_01870	ENOG4108JQ1	Dehydrogenase
FRD49_01875	ENOG4105CQB	FAD linked oxidase domain protein
FRD49_01890	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
FRD49_01895	ENOG4105NF4	modulator of drug activity
FRD49_01905	ENOG4107QF7	multi-drug
FRD49_01910	ENOG4105EM2	membrane
FRD49_01915	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FRD49_01920	ENOG4105IPI	Membrane
FRD49_01925	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
FRD49_01955	ENOG4108IQI	permease
FRD49_01960	ENOG4105D82	Glutamate dehydrogenase
FRD49_01965	ENOG4105C8Y	Acetylornithine aminotransferase
FRD49_01975	ENOG4105C26	Dehydrogenase
FRD49_02000	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FRD49_02065	ENOG4105W87	Cbs domain
FRD49_02070	ENOG41067S9	phage shock protein C, PspC
FRD49_02080	ENOG4105CSU	acyl-Coa dehydrogenase
FRD49_02095	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FRD49_02110	ENOG4105ECY	inositol monophosphatase
FRD49_02115	ENOG4105C1J	atp-dependent rna helicase
FRD49_02120	ENOG4105DHJ	ABC, transporter
FRD49_02125	ENOG4105CY3	ABC transporter, permease
FRD49_02135	ENOG4105E3I	toluene tolerance
FRD49_02145	ENOG4107QUT	magnesium and cobalt transport protein CorA
FRD49_02150	ENOG4108URH	decarboxylase
FRD49_02160	ENOG4105MJ2	Competence protein
FRD49_02165	ENOG4105CB5	ATP-dependent DNA helicase recG
FRD49_02185	ENOG4105C29	acyl-CoA thioesterase
FRD49_02190	ENOG4105CK2	sodium dicarboxylate symporter
FRD49_02205	ENOG4105KPV	Transcriptional regulator
FRD49_02210	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FRD49_02215	ENOG4105D7A	ATP-binding protein
FRD49_02220	ENOG4105C28	cystathionine
FRD49_02225	ENOG41089BK	Glutamine amido-transferase
FRD49_02235	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FRD49_02240	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FRD49_02335	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FRD49_02340	ENOG41067V7	50S ribosomal protein L36
FRD49_02350	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FRD49_02375	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_02410	ENOG4105VKU	nucleicacid-binding protein
FRD49_02415	ENOG4105DGW	oligopeptidase A
FRD49_02420	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FRD49_02465	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FRD49_02475	ENOG4108594	Permease of the drug metabolite transporter
FRD49_02480	ENOG4107S2Z	UPF0761 membrane protein
FRD49_02485	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FRD49_02515	ENOG4105C9A	Phoh family
FRD49_02525	ENOG4105E4C	Lytic transglycosylase catalytic
FRD49_02555	ENOG4105D6S	protein involved in catabolism of external DNA
FRD49_02560	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FRD49_02610	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_02615	ENOG4108RZE	Tetr family transcriptional regulator
FRD49_02630	ENOG4107QX3	carboxylase
FRD49_02635	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_02675	ENOG4105KB2	stringent starvation protein b
FRD49_02680	ENOG4107MKT	Stringent starvation protein a
FRD49_02685	ENOG4108UJD	30S ribosomal protein S9
FRD49_02690	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FRD49_02695	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FRD49_02700	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FRD49_02705	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FRD49_02725	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FRD49_02735	ENOG4107RZC	phospholipase d
FRD49_02745	ENOG4105UYK	outer membrane protein a
FRD49_02750	ENOG4108KHX	Diguanylate cyclase
FRD49_02795	ENOG4107QPB	Beta-lactamase domain protein
FRD49_02800	ENOG4107U2T	alpha beta
FRD49_02810	ENOG4105NAU	thioesterase Superfamily protein
FRD49_02845	ENOG4105K9H	YciI-like protein
FRD49_02855	ENOG4105DB7	PHP domain protein
FRD49_02860	ENOG4105FFC	UPF0187 protein
FRD49_02870	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FRD49_02875	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FRD49_02880	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FRD49_02885	ENOG4105VIE	preprotein translocase, subunit YajC
FRD49_02995	ENOG4105CVR	type I restriction-modification system
FRD49_03000	ENOG4105CB5	ATP-dependent DNA helicase recG
FRD49_03005	ENOG4105EKX	Restriction modification system DNA (Specificity
FRD49_03020	ENOG4105DZR	Type I site-specific deoxyribonuclease
FRD49_03025	ENOG4107R3N	Filamentation induced by cAMP protein fic
FRD49_03030	ENOG4105BZU	Histidine kinase
FRD49_03035	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FRD49_03040	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FRD49_03050	ENOG4108I6E	Sulfatase
FRD49_03060	ENOG4107BJW	polysaccharide deacetylase
FRD49_03070	ENOG4105CG5	Glycosyl transferase (Group 1
FRD49_03115	ENOG4105UGU	tonB-dependent Receptor
FRD49_03135	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
FRD49_03140	ENOG4105CSU	acyl-Coa dehydrogenase
FRD49_03145	ENOG4105CSU	acyl-Coa dehydrogenase
FRD49_03155	ENOG4105EB3	Histidine kinase
FRD49_03160	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FRD49_03165	ENOG4105CNG	UPF0061 protein
FRD49_03185	ENOG4108WBT	adenosyltransferase
FRD49_03200	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FRD49_03240	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FRD49_03260	ENOG4105D3R	alkyl hydroperoxide reductase
FRD49_03275	ENOG4105CSH	Transporter
FRD49_03280	ENOG4108UT2	hemolysin iii
FRD49_03290	ENOG41082BV	acetyltransferase
FRD49_03310	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_03315	ENOG4108R6W	Transcriptional regulator, ARAC family
FRD49_03325	ENOG4105TW1	Carbohydrate-selective porin OprB
FRD49_03330	ENOG4105DZG	Dehydrogenase
FRD49_03335	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FRD49_03355	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_03365	ENOG4108WHA	ompa motb domain protein
FRD49_03370	ENOG4105E0Y	RtcB Protein
FRD49_03375	ENOG4108IQI	permease
FRD49_03385	ENOG4105C2W	permease
FRD49_03405	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FRD49_03415	ENOG4108VX5	3-methyladenine DNA glycosylase
FRD49_03420	ENOG4105CHB	tonB-dependent Receptor
FRD49_03425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_03440	ENOG4105T95	Thiol disulfide interChange protein
FRD49_03445	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FRD49_03455	ENOG4105K78	MarR family Transcriptional regulator
FRD49_03460	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FRD49_03465	ENOG4105KWI	UPF0339 protein
FRD49_03490	ENOG4108UNF	response regulator
FRD49_03495	ENOG4105M3Z	response regulator
FRD49_03500	ENOG4108ZGA	chew protein
FRD49_03505	ENOG4105C8Q	Methyl-accepting chemotaxis
FRD49_03510	ENOG4105CBS	Chea signal transduction histidine kinase
FRD49_03535	ENOG4105WD1	Membrane
FRD49_03540	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FRD49_03580	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FRD49_03590	ENOG4105EM2	membrane
FRD49_03595	ENOG4105C2C	drug resistance transporter, Bcr CflA
FRD49_03620	ENOG4105BZG	amino acid carrier protein
FRD49_03625	ENOG4105D78	K07001 NTE family protein
FRD49_03630	ENOG4105C7B	Threonine dehydratase
FRD49_03665	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FRD49_03675	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FRD49_03680	ENOG4105DFF	Rod shape-determining protein mreb
FRD49_03685	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FRD49_03690	ENOG4105VQ7	Rod shape-determining protein MreD
FRD49_03695	ENOG4108Z03	MAF-like protein
FRD49_03700	ENOG4105C03	ribonuclease
FRD49_03710	ENOG4105D8T	Acyltransferase
FRD49_03720	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
FRD49_03735	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
FRD49_03740	ENOG4108R6W	Transcriptional regulator, ARAC family
FRD49_03760	ENOG4105CF7	AraC family transcriptional regulator
FRD49_03790	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FRD49_03795	ENOG4105E09	nadh pyrophosphatase
FRD49_03800	ENOG4105C85	amino acid
FRD49_03805	ENOG4105C7F	AcnD-accessory protein PrpF
FRD49_03810	ENOG4105CTB	Polyprenyl synthetase
FRD49_03815	ENOG4105MSB	protein, conserved in bacteria
FRD49_03830	ENOG4105D78	K07001 NTE family protein
FRD49_03850	ENOG4105DIJ	Phosphoethanolamine transferase
FRD49_03855	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FRD49_03860	ENOG4105DHQ	Histidine kinase
FRD49_03880	ENOG4108M0I	Transcriptional regulator
FRD49_03900	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FRD49_03920	ENOG4105K8R	UPF0145 protein
FRD49_03925	ENOG4105K8R	UPF0145 protein
FRD49_03930	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FRD49_03935	ENOG4105BZS	acriflavin resistance protein
FRD49_03940	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FRD49_03945	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FRD49_03975	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FRD49_03990	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FRD49_03995	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FRD49_04000	ENOG4105KVH	Transcriptional regulator
FRD49_04010	ENOG4105CUB	amino acid
FRD49_04025	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FRD49_04030	ENOG41084BA	UPF0250 protein
FRD49_04035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FRD49_04065	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
FRD49_04070	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
FRD49_04080	ENOG4105E33	succinate dehydrogenase
FRD49_04095	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FRD49_04100	ENOG4105C7S	Dehydrogenase
FRD49_04105	ENOG4107QN2	dihydrolipoyl dehydrogenase
FRD49_04115	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FRD49_04125	ENOG4105CKW	Inner membrane protein yedI
FRD49_04130	ENOG4105CGZ	zinc metallopeptidase
FRD49_04135	ENOG4105EEQ	Na H antiporter
FRD49_04150	ENOG4105PNM	synthesis protein
FRD49_04170	ENOG41080TK	Universal stress protein
FRD49_04180	ENOG4108UQ8	endoribonuclease L-psp
FRD49_04185	ENOG4108IG5	Transcriptional regulator
FRD49_04195	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FRD49_04200	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FRD49_04220	ENOG4105HBR	Rna-binding protein
FRD49_04230	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FRD49_04235	ENOG4105EEI	dihydropteroate synthase
FRD49_04285	ENOG4105CSH	Transporter
FRD49_04290	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FRD49_04295	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FRD49_04310	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FRD49_04325	ENOG41080IJ	Diacylglycerol kinase
FRD49_04335	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FRD49_04340	ENOG4105BZS	acriflavin resistance protein
FRD49_04355	ENOG4105E4C	Lytic transglycosylase catalytic
FRD49_04380	ENOG4108RRZ	Transcription elongation factor GreB
FRD49_04395	ENOG4105CEY	Amp-dependent synthetase and ligase
FRD49_04405	ENOG4105YCT	UPF0386 protein
FRD49_04445	ENOG4108IND	Tetr family transcriptional regulator
FRD49_04450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_04455	ENOG4107TTQ	Alpha beta hydrolase fold
FRD49_04465	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
FRD49_04475	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FRD49_04480	ENOG4105BZS	acriflavin resistance protein
FRD49_04500	ENOG4105BZW	Glycerate kinase
FRD49_04505	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
FRD49_04515	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FRD49_04530	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FRD49_04540	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FRD49_04545	ENOG4105C85	amino acid
FRD49_04550	ENOG4105C85	amino acid
FRD49_04560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FRD49_04570	ENOG4105N14	lysine exporter protein LysE YggA
FRD49_04575	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FRD49_04580	ENOG4105BZJ	Electron transfer flavoprotein
FRD49_04585	ENOG4105C10	Electron transfer flavoprotein
FRD49_04595	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FRD49_04600	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRD49_04605	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FRD49_04635	ENOG4107KET	secretion protein, HlyD family
FRD49_04665	ENOG4105D60	lipoprotein releasing system transmembrane protein
FRD49_04670	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FRD49_04675	ENOG4108EC8	DNA internalization-related competence protein ComEC
FRD49_04685	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FRD49_04690	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
FRD49_04695	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FRD49_04705	ENOG4105C02	permease
FRD49_04755	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FRD49_04760	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FRD49_04770	ENOG4105M8F	Biopolymer transport protein exbD tolR
FRD49_04775	ENOG4105E02	MotA TolQ exbB proton channel
FRD49_04780	ENOG4107YD3	Thioesterase
FRD49_04785	ENOG4105CH2	amidohydrolase
FRD49_04805	ENOG4108ETH	Formylglycinamide ribotide synthetase
FRD49_04810	ENOG4105C2C	drug resistance transporter, Bcr CflA
FRD49_04825	ENOG4105EGD	dinuclear metal center protein, YbgI family
FRD49_04830	ENOG4108UKI	Enoyl-CoA hydratase
FRD49_04850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRD49_04865	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FRD49_04870	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FRD49_04885	ENOG4107R11	Transcriptional regulator
FRD49_04890	ENOG4108IJ6	ABC transporter
FRD49_04900	ENOG4108I5D	sulfate abc transporter
FRD49_04910	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
FRD49_04915	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
FRD49_04920	ENOG4105HHA	aminodeoxychorismate lyase
FRD49_04935	ENOG4108IYU	L-aspartate oxidase
FRD49_04940	ENOG4105C0H	protease
FRD49_04955	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FRD49_04960	ENOG4105C3F	Signal peptidase i
FRD49_04975	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FRD49_04985	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
FRD49_04990	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FRD49_04995	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
FRD49_05000	ENOG4105EMU	Dehydrogenase
FRD49_05040	ENOG4105BZU	Histidine kinase
FRD49_05050	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FRD49_05095	ENOG4107QS8	(LipO)protein
FRD49_05100	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FRD49_05105	ENOG4105EA8	2-Nitropropane dioxygenase
FRD49_05145	ENOG4107R8N	Glycosyl transferase, family 2
FRD49_05160	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FRD49_05165	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FRD49_05170	ENOG4105CEP	NADH dehydrogenase
FRD49_05175	ENOG4105DZ1	carboxypeptidase
FRD49_05185	ENOG4105E9K	Isocitrate dehydrogenase
FRD49_05190	ENOG4108R99	pseudouridine synthase
FRD49_05215	ENOG4105CBP	Major Facilitator
FRD49_05225	ENOG4108ETY	sodium dicarboxylate symporter
FRD49_05230	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FRD49_05260	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FRD49_05275	ENOG4105D3G	Pseudouridine synthase
FRD49_05280	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
FRD49_05295	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FRD49_05320	ENOG4108JPW	Aminotransferase
FRD49_05325	ENOG4105DY8	decarboxylase
FRD49_05335	ENOG4105F7P	transcriptional regulator AsnC family
FRD49_05340	ENOG4107RA9	decarboxylase
FRD49_05345	ENOG4105C85	amino acid
FRD49_05350	ENOG4105CVA	phosphate
FRD49_05355	ENOG4105C8U	phosphate abc transporter
FRD49_05365	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FRD49_05370	ENOG4105ERU	peptidase
FRD49_05385	ENOG4108R5S	membrane
FRD49_05390	ENOG4107QTF	adenylosuccinate lyase
FRD49_05410	ENOG4108Z0R	Transferase
FRD49_05415	ENOG4105DZ1	carboxypeptidase
FRD49_05435	ENOG4108K5P	(LipO)protein
FRD49_05440	ENOG4105EJC	lysr family transcriptional regulator
FRD49_05445	ENOG4105DAN	ATP-dependent protease
FRD49_05460	ENOG4105DHU	Bile acid
FRD49_05470	ENOG41066DG	(EAL) domain protein
FRD49_05480	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FRD49_05485	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FRD49_05490	ENOG4105D22	carbon starvation protein
FRD49_05495	ENOG4105VCD	cytoplasmic protein
FRD49_05535	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FRD49_05560	ENOG4105WWK	YheO domain protein
FRD49_05565	ENOG4105C2I	pirin domain protein
FRD49_05585	ENOG4105NX3	Membrane
FRD49_05615	ENOG4105EUJ	GTP cyclohydrolase i
FRD49_05625	ENOG4105C7W	Xanthine dehydrogenase
FRD49_05635	ENOG4108DG9	Smr protein MutS2
FRD49_05670	ENOG4105CD8	aminopeptidase N
FRD49_05675	ENOG4105DDQ	anthranilate synthase
FRD49_05700	ENOG4105C5F	glutamine synthetase
FRD49_05710	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FRD49_05745	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FRD49_05750	ENOG4107QNR	UPF0135 protein
FRD49_05755	ENOG4105C0H	protease
FRD49_05765	ENOG4105C6K	Malic enzyme
FRD49_05770	ENOG4105BZU	Histidine kinase
FRD49_05775	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FRD49_05780	ENOG4105SYT	Methylenetetrahydrofolate reductase
FRD49_05785	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FRD49_05800	ENOG4107QPN	acyl-Coa dehydrogenase
FRD49_05805	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FRD49_05810	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
FRD49_05820	ENOG4107RNU	major facilitator superfamily MFS_1
FRD49_05830	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FRD49_05835	ENOG4105CE9	30S ribosomal protein S2
FRD49_05875	ENOG4105CVE	Lytic murein transglycosylase
FRD49_05880	ENOG4105CNI	cell division protein FtsW
FRD49_05895	ENOG4105E3A	(ABC) transporter
FRD49_05900	ENOG4105DA5	(ABC) transporter
FRD49_05930	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FRD49_05940	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FRD49_05950	ENOG4105E89	ABC transporter
FRD49_05955	ENOG4105DSP	amino acid AbC transporter
FRD49_05960	ENOG4106YG3	ABC transporter
FRD49_05965	ENOG4108JEH	abc transporter atp-binding protein
FRD49_05975	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FRD49_05980	ENOG4105CFP	Peptidase U32
FRD49_05985	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FRD49_05990	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FRD49_05995	ENOG4105DP0	ferredoxin-NADP reductase
FRD49_06000	ENOG4108R96	Methyltransferase, YaeB family
FRD49_06010	ENOG4107QHF	type ii secretion system protein e
FRD49_06015	ENOG4105WXI	Bacterial OB fold (BOF) protein
FRD49_06020	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FRD49_06025	ENOG4105DHQ	Histidine kinase
FRD49_06035	ENOG4105M6F	mutator MutT protein
FRD49_06045	ENOG4105BZ4	penicillin-binding protein
FRD49_06050	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FRD49_06055	ENOG4105VUT	cytoplasmic protein
FRD49_06060	ENOG4107QYG	anthranilate phosphoribosyltransferase
FRD49_06070	ENOG4105CK2	sodium dicarboxylate symporter
FRD49_06075	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_06085	ENOG4105NIV	Esterase
FRD49_06090	ENOG4105CQC	Prephenate dehydratase
FRD49_06095	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FRD49_06105	ENOG4105E6M	Sulphatase-modifying factor protein
FRD49_06110	ENOG4105CIN	aminoacyl-histidine dipeptidase
FRD49_06115	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FRD49_06140	ENOG4105M08	Membrane
FRD49_06145	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FRD49_06155	ENOG4105VEQ	Cold shock protein
FRD49_06160	ENOG4105C1J	atp-dependent rna helicase
FRD49_06170	ENOG41069NU	Nitroreductase
FRD49_06205	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FRD49_06220	ENOG4105C5I	Dehydrogenase
FRD49_06225	ENOG4105ERG	peptidase m48, ste24p
FRD49_06230	ENOG4105KTH	gatB Yqey
FRD49_06235	ENOG4105VCC	30S ribosomal protein S21
FRD49_06260	ENOG4105D9P	serine threonine protein kinase
FRD49_06285	ENOG4105D5K	Hemolysin activator protein
FRD49_06375	ENOG4105EVZ	LysR family transcriptional regulator
FRD49_06380	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FRD49_06385	ENOG4105C26	Dehydrogenase
FRD49_06410	ENOG4108D32	Methyltransferase
FRD49_06420	ENOG4105H4F	exported protein
FRD49_06440	ENOG4105D6U	Sodium Glutamate Symporter
FRD49_06445	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FRD49_06450	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
FRD49_06515	ENOG4105EQ2	LysR family Transcriptional regulator
FRD49_06520	ENOG4105ENX	hydrolase
FRD49_06530	ENOG410642W	LysR family Transcriptional regulator
FRD49_06605	ENOG4105F1S	paraquat-inducible protein a
FRD49_06610	ENOG4105DY2	Paraquat-inducible protein b
FRD49_06620	ENOG4105VT2	5-hydroxyisourate hydrolase
FRD49_06635	ENOG4105GR3	Histidine kinase
FRD49_06660	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FRD49_06670	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FRD49_06675	ENOG4105DHQ	Histidine kinase
FRD49_06680	ENOG4105ETX	regulatoR
FRD49_06720	ENOG4105CK2	sodium dicarboxylate symporter
FRD49_06735	ENOG4108UMI	ABC transporter, permease
FRD49_06740	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FRD49_06750	ENOG4105C12	Phosphoribosylglycinamide synthetase
FRD49_06755	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FRD49_06760	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FRD49_06810	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FRD49_06815	ENOG4105CDU	Replicative dna helicase
FRD49_06840	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
FRD49_06845	ENOG4105CCU	oxidase (Subunit III)
FRD49_06850	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FRD49_06855	ENOG4105E2S	oxidase) subunit II
FRD49_06885	ENOG4105CND	Glycosyl transferase, family 2
FRD49_06890	ENOG4106FQ9	Biofilm PGA synthesis protein PgaD
FRD49_06900	ENOG4105DEN	Luciferase family
FRD49_06925	ENOG4105CC0	LysR family Transcriptional regulator
FRD49_06940	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FRD49_06945	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FRD49_06950	ENOG4105GVF	(ABC) transporter
FRD49_06965	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_06975	ENOG4108MEJ	flavin reductase domain protein
FRD49_06980	ENOG4105D06	uba thif-type nad fad binding protein
FRD49_07000	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FRD49_07005	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
FRD49_07010	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
FRD49_07015	ENOG4105C08	Histidine kinase
FRD49_07020	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
FRD49_07025	ENOG4105CFQ	glutamine synthetase
FRD49_07040	ENOG4107S74	Lysophospholipid transporter LplT
FRD49_07045	ENOG4105CFU	surface antigen
FRD49_07065	ENOG4107QIJ	Aconitate hydratase 2
FRD49_07075	ENOG4105EYW	Ion transport protein
FRD49_07080	ENOG4105F27	Major Facilitator
FRD49_07090	ENOG4105DZ2	Transcriptional regulator
FRD49_07125	ENOG4105K8N	protein family UPF0079, ATPase
FRD49_07130	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FRD49_07140	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FRD49_07145	ENOG4108TZV	Membrane
FRD49_07150	ENOG4108RCM	Nitroreductase
FRD49_07175	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FRD49_07180	ENOG4107FQ9	ethanolamine ammonia-lyase
FRD49_07185	ENOG4105CPD	ethanolamine ammonia-lyase
FRD49_07190	ENOG4107R55	ethanolamine transporter
FRD49_07200	ENOG4107RR1	TRANSCRIPTIONal
FRD49_07210	ENOG4105C0A	alcohol dehydrogenase
FRD49_07215	ENOG4107QUV	Domain protein
FRD49_07225	ENOG4105F4I	Transcriptional regulator
FRD49_07245	ENOG4105CD8	aminopeptidase N
FRD49_07270	ENOG4108D1K	outer membrane usher protein
FRD49_07310	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
FRD49_07315	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_07350	ENOG4105DUU	IucA IucC family protein
FRD49_07360	ENOG4105DJU	Siderophore biosynthesis protein
FRD49_07365	ENOG4105CIF	Ornithine Cyclodeaminase
FRD49_07375	ENOG4105CUY	Mechanosensitive ion channel
FRD49_07445	ENOG4105C5H	ABC transporter
FRD49_07450	ENOG41081QV	Universal stress protein
FRD49_07465	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
FRD49_07475	ENOG4105DKK	Benzoate
FRD49_07480	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_07485	ENOG4108NIW	Leucine export protein LeuE
FRD49_07490	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FRD49_07495	ENOG4105C5Q	Transcriptional regulator
FRD49_07505	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_07510	ENOG4105CHR	reductase
FRD49_07545	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FRD49_07550	ENOG4105HSS	phospholipase C
FRD49_07560	ENOG4105C0A	alcohol dehydrogenase
FRD49_07570	ENOG4108RWI	nicotinamidase
FRD49_07625	ENOG4105CBC	glutamate synthase
FRD49_07650	ENOG4108D1K	outer membrane usher protein
FRD49_07665	ENOG4105D8G	Major Facilitator superfamily
FRD49_07675	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FRD49_07680	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FRD49_07700	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRD49_07710	ENOG4107QZF	nitrite reductase NADPH large subunit
FRD49_07715	ENOG4108IFG	nitrite reductase, (NAD(P)H)
FRD49_07750	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FRD49_07755	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FRD49_07765	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FRD49_07770	ENOG4105T38	integral membrane protein
FRD49_07790	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
FRD49_07795	ENOG4105CMR	udp-glucose 4-epimerase
FRD49_07855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FRD49_07860	ENOG4105CUX	Signal transduction histidine kinase
FRD49_07885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FRD49_07890	ENOG4105KNE	Phosphatidate cytidylyltransferase
FRD49_07900	ENOG4105DZP	Membrane-associated zinc metalloprotease
FRD49_07925	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRD49_07940	ENOG4105Y3E	Modulates RecA activity (By similarity)
FRD49_07950	ENOG4105VEJ	Heat shock protein
FRD49_07955	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
FRD49_07975	ENOG4105F7P	transcriptional regulator AsnC family
FRD49_07985	ENOG4105C85	amino acid
FRD49_08010	ENOG4105CHH	sulfate transporter
FRD49_08015	ENOG4108RAV	Conserved protein
FRD49_08020	ENOG4105D8V	Glucose sorbosone dehydrogenase
FRD49_08030	ENOG4105BZU	Histidine kinase
FRD49_08045	ENOG4105DM4	PTS System
FRD49_08050	ENOG4105DE4	1-phosphofructokinase
FRD49_08055	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FRD49_08080	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FRD49_08085	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FRD49_08090	ENOG4105CC0	LysR family Transcriptional regulator
FRD49_08100	ENOG4105M2J	Glutaredoxin
FRD49_08105	ENOG4105C8Y	Acetylornithine aminotransferase
FRD49_08110	ENOG4105C2X	Arabinose 5-phosphate isomerase
FRD49_08140	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FRD49_08150	ENOG41068P6	UPF0319 protein
FRD49_08170	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FRD49_08175	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FRD49_08185	ENOG4105PV3	Inner membrane protein yqiJ
FRD49_08200	ENOG4105E0K	tonB-dependent siderophore receptor
FRD49_08210	ENOG4105HDD	phospholipase
FRD49_08215	ENOG4105CZN	Potassium uptake protein
FRD49_08225	ENOG4105C7B	Threonine dehydratase
FRD49_08255	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FRD49_08260	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FRD49_08270	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FRD49_08285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_08330	ENOG4107VMU	Membrane
FRD49_08340	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FRD49_08350	ENOG4107QP7	CoA-transferase subunit A
FRD49_08355	ENOG4107QNJ	CoA-transferase subunit B
FRD49_08360	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_08365	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
FRD49_08370	ENOG4105F2Z	3-oxoadipate enol-lactonase
FRD49_08375	ENOG4105D2S	major facilitator superfamily
FRD49_08380	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
FRD49_08385	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
FRD49_08390	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
FRD49_08395	ENOG4105FF2	Type I DHQase
FRD49_08400	ENOG4106JPM	3-dehydroshikimate dehydratase
FRD49_08405	ENOG4105TW1	Carbohydrate-selective porin OprB
FRD49_08410	ENOG4105DZG	Dehydrogenase
FRD49_08420	ENOG4105MD1	YeeE YedE family protein
FRD49_08435	ENOG4107HP6	Transcriptional regulator
FRD49_08440	ENOG4108PTX	LysR family Transcriptional regulator
FRD49_08445	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_08470	ENOG4105DNH	Major Facilitator
FRD49_08480	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FRD49_08500	ENOG4105FUY	alpha subunit
FRD49_08510	ENOG4105CHR	reductase
FRD49_08530	ENOG4105F11	amine oxidase
FRD49_08540	ENOG4105C26	Dehydrogenase
FRD49_08550	ENOG4105F2Z	3-oxoadipate enol-lactonase
FRD49_08555	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_08560	ENOG4107QNJ	CoA-transferase subunit B
FRD49_08565	ENOG4107QP7	CoA-transferase subunit A
FRD49_08575	ENOG4105NN7	muconolactone delta-isomerase
FRD49_08580	ENOG4105DTQ	mandelate racemase muconate lactonizing
FRD49_08585	ENOG4108KB2	LysR family Transcriptional regulator
FRD49_08595	ENOG4107EJG	GntR family transcriptional regulator
FRD49_08615	ENOG4105CZJ	Aldehyde dehydrogenase
FRD49_08640	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRD49_08665	ENOG4107Z3H	Transcriptional regulator, TetR family
FRD49_08680	ENOG41082JN	Transcriptional regulator
FRD49_08715	ENOG4105FDP	GntR family transcriptional regulator
FRD49_08720	ENOG4106KR7	LysR family Transcriptional regulator
FRD49_08735	ENOG4105CW7	secretion protein, HlyD family
FRD49_08750	ENOG4105CZJ	Aldehyde dehydrogenase
FRD49_08755	ENOG4105C01	Dihydroxy-acid dehydratase
FRD49_08765	ENOG4105DDW	LysR family Transcriptional regulator
FRD49_08770	ENOG4105EXW	epimerase dehydratase
FRD49_08780	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FRD49_08790	ENOG4105EHG	Permease protein
FRD49_08795	ENOG4105E0A	ABC, transporter
FRD49_08815	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FRD49_08910	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FRD49_08950	ENOG4105DQ4	alcohol dehydrogenase
FRD49_08955	ENOG4105EMU	Dehydrogenase
FRD49_08960	ENOG4105ENX	hydrolase
FRD49_08965	ENOG4105EQ2	LysR family Transcriptional regulator
FRD49_08990	ENOG4105E0F	Histidine kinase
FRD49_08995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRD49_09000	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FRD49_09020	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FRD49_09095	ENOG4105X0I	Fimbrial
FRD49_09145	ENOG4107RZC	phospholipase d
FRD49_09165	ENOG4108IGT	Dipeptidase
FRD49_09200	ENOG4107T31	5'-nucleotidase
FRD49_09210	ENOG4105D05	Receptor
FRD49_09215	ENOG4105BZS	acriflavin resistance protein
FRD49_09220	ENOG4105WQI	isochorismatase
FRD49_09225	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
FRD49_09230	ENOG4105E4F	Isochorismate synthase
FRD49_09235	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
FRD49_09245	ENOG41085A6	mbth domain-containing protein
FRD49_09250	ENOG4105CEY	Amp-dependent synthetase and ligase
FRD49_09280	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FRD49_09285	ENOG4105E0C	molybdate abc transporter
FRD49_09290	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FRD49_09295	ENOG4105F4R	Transcriptional regulator mode
FRD49_09300	ENOG4108Q89	anthranilate 1,2-dioxygenase large subunit
FRD49_09305	ENOG4108YS2	small subunit
FRD49_09310	ENOG4105F57	Anthranilate dioxygenase reductase
FRD49_09335	ENOG4105CHR	reductase
FRD49_09345	ENOG4105D2S	major facilitator superfamily
FRD49_09350	ENOG4105CF7	AraC family transcriptional regulator
FRD49_09355	ENOG4105DTD	Dehydrogenase
FRD49_09360	ENOG4105CY2	Citrate transporter
FRD49_09365	ENOG4105C5X	domain protein
FRD49_09395	ENOG4105G2Y	Transcriptional regulator
FRD49_09415	ENOG4108M0I	Transcriptional regulator
FRD49_09430	ENOG4105CRW	Short chain fatty acid transporter
FRD49_09435	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_09445	ENOG4107YNJ	LysR family Transcriptional regulator
FRD49_09460	ENOG4108IJ0	Aspartate ammonia-lyase
FRD49_09470	ENOG4105CSH	Transporter
FRD49_09490	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FRD49_09495	ENOG4106FTQ	Taurine ABC transporter, periplasmic
FRD49_09510	ENOG4105FDP	GntR family transcriptional regulator
FRD49_09520	ENOG4105UEI	Transcriptional Regulator AraC Family
FRD49_09535	ENOG4108VCT	Sulfite exporter TauE/SafE
FRD49_09545	ENOG4107QPB	Beta-lactamase domain protein
FRD49_09555	ENOG4105FFC	UPF0187 protein
FRD49_09565	ENOG4105CHR	reductase
FRD49_09580	ENOG4105CPP	Dehydrogenase, E1 component
FRD49_09585	ENOG4107R0V	Pyruvate dehydrogenase
FRD49_09590	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FRD49_09605	ENOG4105BZU	Histidine kinase
FRD49_09615	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FRD49_09620	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FRD49_09665	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FRD49_09680	ENOG4105C28	cystathionine
FRD49_09690	ENOG4105F2W	methyltransferase
FRD49_09715	ENOG4105K59	histidine triad (HIT) protein
FRD49_09740	ENOG4107QWP	ABC-2 type transporter
FRD49_09745	ENOG4107QWP	ABC-2 type transporter
FRD49_09750	ENOG4105CJ1	ABC, transporter
FRD49_09770	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRD49_09775	ENOG4105CNM	Receptor
FRD49_09795	ENOG4107TSN	permease
FRD49_09800	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FRD49_09810	ENOG4105CHB	tonB-dependent Receptor
FRD49_09825	ENOG4107TB6	phosphoglycerate mutase
FRD49_09830	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FRD49_09835	ENOG4108YZT	Adenosylcobinamide kinase
FRD49_09855	ENOG4108Z66	YbaK ebsC protein
FRD49_09870	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_09875	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_09880	ENOG4105EEF	Alkane 1-monooxygenase
FRD49_09885	ENOG4105E7U	AraC family transcriptional regulator
FRD49_09890	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FRD49_09895	ENOG4105K70	DNA-binding protein
FRD49_09910	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FRD49_09920	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FRD49_09925	ENOG4108Z4V	iron-sulfur cluster assembly
FRD49_09940	ENOG4108ZIT	Ferredoxin, 2FE-2S
FRD49_09945	ENOG4105F8J	Adenylate Guanylate cyclase
FRD49_09955	ENOG4108JA2	transcriptioN-repair coupling factor
FRD49_09975	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FRD49_09980	ENOG4105K4T	epimerase
FRD49_09995	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FRD49_10010	ENOG4108JQ6	ABC transporter
FRD49_10015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FRD49_10025	ENOG4105DGW	oligopeptidase A
FRD49_10050	ENOG4108DNJ	Pfam:TonB
FRD49_10065	ENOG4105SG9	biopolymer transport protein, ExbD
FRD49_10075	ENOG4107QP3	malate synthase g
FRD49_10080	ENOG4105D6Z	AFG1 family ATPase
FRD49_10090	ENOG4107RN6	Monooxygenase
FRD49_10095	ENOG4105DWU	Membrane
FRD49_10110	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FRD49_10115	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FRD49_10130	ENOG4108Z6B	deaminase
FRD49_10150	ENOG4108RTD	type II secretion system protein K
FRD49_10155	ENOG4108WWZ	General secretion pathway protein J
FRD49_10175	ENOG4105F8V	Hydrolase, tatD family
FRD49_10185	ENOG4107QRG	dna polymerase iii
FRD49_10195	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FRD49_10200	ENOG4105BZ1	(ABC) transporter
FRD49_10215	ENOG4105FA0	parb-like partition protein
FRD49_10220	ENOG4107QJE	Chromosome Partitioning Protein
FRD49_10230	ENOG4108S0S	Nucleotidyl transferase
FRD49_10235	ENOG4105EHM	Aminoglycoside phosphotransferase
FRD49_10240	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FRD49_10245	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FRD49_10250	ENOG4105D2N	Aldolase
FRD49_10270	ENOG4108UHJ	MAF-like protein
FRD49_10275	ENOG4105EZE	Cupin 4 family protein
FRD49_10285	ENOG41080HT	Transcriptional regulator, arsr family
FRD49_10295	ENOG4105XPP	Protein of unknown function (DUF1275)
FRD49_10300	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FRD49_10305	ENOG4105BZ1	(ABC) transporter
FRD49_10315	ENOG4108ZX5	transcriptional regulator
FRD49_10325	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FRD49_10330	ENOG4105CK7	Sodium proline symporter
FRD49_10335	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_10345	ENOG4105C26	Dehydrogenase
FRD49_10350	ENOG4105YGK	Pfam:UPF0157
FRD49_10365	ENOG4108T58	Mg2 transport protein CorA
FRD49_10375	ENOG4108YYC	ycei family
FRD49_10395	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FRD49_10435	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FRD49_10440	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FRD49_10460	ENOG4105X0I	Fimbrial
FRD49_10465	ENOG4105GQR	Chaperone
FRD49_10505	ENOG4108IPJ	Membrane
FRD49_10515	ENOG4105ETS	cytosine purines uracil thiamine allantoin
FRD49_10525	ENOG4105CC0	LysR family Transcriptional regulator
FRD49_10545	ENOG41067SE	Tetr family transcriptional regulator
FRD49_10560	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_10570	ENOG4105CDA	abc transporter atp-binding protein
FRD49_10575	ENOG4105DRP	amino acid AbC transporter
FRD49_10580	ENOG4105EAD	ABC transporter
FRD49_10595	ENOG4107T8P	acyl-Coa dehydrogenase
FRD49_10610	ENOG4105D01	(LipO)protein
FRD49_10615	ENOG4105D01	(LipO)protein
FRD49_10620	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FRD49_10625	ENOG4108UMI	ABC transporter, permease
FRD49_10630	ENOG4105C3G	gtp-binding protein
FRD49_10655	ENOG4108UMN	azlc family
FRD49_10660	ENOG4105ZED	uncharacterized protein ygaH
FRD49_10685	ENOG410829K	Lysine exporter protein (Lyse ygga)
FRD49_10690	ENOG4105E7U	AraC family transcriptional regulator
FRD49_10695	ENOG4108V06	Glutathione peroxidase
FRD49_10705	ENOG4105CHM	Aminotransferase
FRD49_10710	ENOG4105CK2	sodium dicarboxylate symporter
FRD49_10720	ENOG4105C0B	DNA polymerase III (alpha subunit)
FRD49_10745	ENOG4108JU3	Alkyl hydroperoxide reductase
FRD49_10760	ENOG4108KB2	LysR family Transcriptional regulator
FRD49_10765	ENOG4105D6J	arsenicaL-resistance protein
FRD49_10770	ENOG41082YX	Transcriptional regulator, arsr family
FRD49_10795	ENOG4105CBN	LysR family transcriptional regulator
FRD49_10805	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
FRD49_10815	ENOG4105E2B	Taurine dioxygenase
FRD49_10820	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
FRD49_10825	ENOG4108IY8	ABC, transporter
FRD49_10830	ENOG4106FTQ	Taurine ABC transporter, periplasmic
FRD49_10840	ENOG4105C54	Major Facilitator superfamily
FRD49_10865	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FRD49_10870	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FRD49_10880	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FRD49_10885	ENOG4108K70	Transcriptional regulator
FRD49_10900	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FRD49_10905	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
FRD49_10920	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
FRD49_10925	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
FRD49_10945	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FRD49_10950	ENOG41067MG	lrgb family
FRD49_10960	ENOG4105CMU	LysR family (Transcriptional regulator
FRD49_10965	ENOG4108SHQ	Glutathione S-transferase
FRD49_10970	ENOG4105CYM	Glutathione S-transferase
FRD49_10975	ENOG4105CBN	LysR family transcriptional regulator
FRD49_10980	ENOG4105CHR	reductase
FRD49_10990	ENOG4105D7W	serine acetyltransferase
FRD49_10995	ENOG4105ESN	nucleotide-binding protein
FRD49_11000	ENOG4105C9B	Cysteine desulfurase
FRD49_11010	ENOG4105EXG	Transcriptional regulator
FRD49_11020	ENOG4105CT1	(ABC) transporter
FRD49_11025	ENOG4107RP9	extracellular solute-binding protein, family 3
FRD49_11030	ENOG4105CDA	abc transporter atp-binding protein
FRD49_11035	ENOG4108HW4	amino acid AbC transporter
FRD49_11040	ENOG4105EAD	ABC transporter
FRD49_11055	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FRD49_11060	ENOG4105BZU	Histidine kinase
FRD49_11070	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_11105	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FRD49_11155	ENOG4105HEI	LysR family (Transcriptional regulator
FRD49_11175	ENOG4105CEY	Amp-dependent synthetase and ligase
FRD49_11180	ENOG4105R8C	Transcriptional regulator
FRD49_11185	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_11190	ENOG4107QX3	carboxylase
FRD49_11195	ENOG4105E39	Enoyl-CoA hydratase
FRD49_11210	ENOG4105CC0	LysR family Transcriptional regulator
FRD49_11225	ENOG4105CSU	acyl-Coa dehydrogenase
FRD49_11235	ENOG4105EQ0	Major Facilitator superfamily
FRD49_11245	ENOG4107QNJ	CoA-transferase subunit B
FRD49_11250	ENOG4107QP7	CoA-transferase subunit A
FRD49_11255	ENOG4107RGD	Major Facilitator superfamily
FRD49_11260	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_11265	ENOG4105E39	Enoyl-CoA hydratase
FRD49_11270	ENOG4105CHR	reductase
FRD49_11275	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FRD49_11280	ENOG4105CHU	acetyl-coa acetyltransferase
FRD49_11290	ENOG4105EQ0	Major Facilitator superfamily
FRD49_11295	ENOG4105EA8	2-Nitropropane dioxygenase
FRD49_11300	ENOG4108UKI	Enoyl-CoA hydratase
FRD49_11315	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_11320	ENOG4107RGD	Major Facilitator superfamily
FRD49_11325	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
FRD49_11330	ENOG4107STF	Involved in phosphonate degradation (By similarity)
FRD49_11340	ENOG4107RCV	ABC transporter, permease
FRD49_11345	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FRD49_11350	ENOG4105C4Y	ABC transporter
FRD49_11360	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
FRD49_11365	ENOG4107HP6	Transcriptional regulator
FRD49_11375	ENOG4105HEI	LysR family (Transcriptional regulator
FRD49_11405	ENOG4105JQN	Transcriptional regulator
FRD49_11410	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FRD49_11430	ENOG4108HW3	(ABC) transporter
FRD49_11440	ENOG4105MRR	Transcriptional regulator (By similarity)
FRD49_11455	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
FRD49_11460	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FRD49_11475	ENOG4105E2A	Dehydrogenase
FRD49_11555	ENOG4107R4J	Chloride channel
FRD49_11560	ENOG4108JIK	carboxylase
FRD49_11580	ENOG4105C5A	transporter
FRD49_11585	ENOG4108WAV	Transcriptional regulator
FRD49_11595	ENOG4108WQI	RNA Polymerase
FRD49_11605	ENOG4105E18	UPF0276 protein
FRD49_11620	ENOG4105CHR	reductase
FRD49_11635	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
FRD49_11650	ENOG4105GNX	MltA-interacting MipA family protein
FRD49_11655	ENOG4105C8Y	Acetylornithine aminotransferase
FRD49_11730	ENOG4105PAD	Hydrolase
FRD49_11750	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
FRD49_11765	ENOG4107TXC	Transcriptional regulator
FRD49_11770	ENOG4105VEQ	Cold shock protein
FRD49_11775	ENOG41089BK	Glutamine amido-transferase
FRD49_11780	ENOG4105C28	cystathionine
FRD49_11790	ENOG4108XM1	transcriptional regulator AsnC family
FRD49_11795	ENOG4105NBK	UPF0345 protein
FRD49_11825	ENOG4105D2S	major facilitator superfamily
FRD49_11855	ENOG4105BZU	Histidine kinase
FRD49_11870	ENOG4105EXG	Transcriptional regulator
FRD49_11875	ENOG4105CSU	acyl-Coa dehydrogenase
FRD49_11885	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
FRD49_11890	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FRD49_11895	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FRD49_11910	ENOG4108Z4U	Ferredoxin
FRD49_11940	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
FRD49_11950	ENOG4105DFG	type I secretion outer membrane protein
FRD49_11955	ENOG4108IUZ	ABC transporter
FRD49_11960	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
FRD49_11970	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
FRD49_11975	ENOG4105C2X	Arabinose 5-phosphate isomerase
FRD49_12040	ENOG4105II7	pyrroline-5-carboxylate reductase
FRD49_12050	ENOG4105VEQ	Cold shock protein
FRD49_12055	ENOG410829K	Lysine exporter protein (Lyse ygga)
FRD49_12085	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FRD49_12150	ENOG4105EUV	Phenol 2-monooxygenase
FRD49_12170	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
FRD49_12180	ENOG4108KB2	LysR family Transcriptional regulator
FRD49_12185	ENOG4105FUY	alpha subunit
FRD49_12190	ENOG4108UKV	benzoate 1,2-dioxygenase
FRD49_12195	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
FRD49_12200	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
FRD49_12205	ENOG4105DKK	Benzoate
FRD49_12210	ENOG4105D2S	major facilitator superfamily
FRD49_12225	ENOG4105CQ7	ATP-dependent helicase
FRD49_12230	ENOG4105D3R	alkyl hydroperoxide reductase
FRD49_12250	ENOG4108JU3	Alkyl hydroperoxide reductase
FRD49_12260	ENOG4108K3A	Glutathione S-transferase
FRD49_12270	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FRD49_12290	ENOG4108TGY	Glutathione S-transferase
FRD49_12300	ENOG4108ZG0	Ompa motb domain protein
FRD49_12305	ENOG4105CD3	dihydroorotase
FRD49_12335	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FRD49_12350	ENOG4108UKZ	OsmC family
FRD49_12355	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FRD49_12360	ENOG4105CPC	Aldo Keto reductase
FRD49_12375	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FRD49_12385	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FRD49_12395	ENOG4105DFP	Integrase
FRD49_12555	ENOG4107ZQ5	Phage-associated protein, HI1409 family
FRD49_12700	ENOG4105CFH	Aspartokinase
FRD49_12710	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FRD49_12720	ENOG4105CPW	cytochrome b561
FRD49_12725	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FRD49_12730	ENOG4105C7N	Xanthine uracil vitamin C permease
FRD49_12740	ENOG4105F95	Monooxygenase
FRD49_12775	ENOG4105F95	Monooxygenase
FRD49_12780	ENOG4105JQZ	Methyltransferase
FRD49_12790	ENOG4107RN6	Monooxygenase
FRD49_12810	ENOG4105DDY	UPF0142 protein ycaO
FRD49_12815	ENOG4105EPF	Outer membrane porin
FRD49_12820	ENOG4105D2S	major facilitator superfamily
FRD49_12830	ENOG4105E3J	oxidoreductase
FRD49_12845	ENOG4108SC4	)-transporter
FRD49_12850	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
FRD49_12865	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_12870	ENOG4105EPF	Outer membrane porin
FRD49_12895	ENOG4108ZX5	transcriptional regulator
FRD49_12900	ENOG4107RGH	Aldehyde dehydrogenase
FRD49_12905	ENOG4105C85	amino acid
FRD49_12925	ENOG4105C26	Dehydrogenase
FRD49_12945	ENOG4105CUB	amino acid
FRD49_12955	ENOG4105C85	amino acid
FRD49_12965	ENOG4107Y60	(LipO)protein
FRD49_12975	ENOG4106B0W	Curli production assembly transport component CsgG
FRD49_13040	ENOG4105CNA	YD repeat protein
FRD49_13060	ENOG4105D01	(LipO)protein
FRD49_13090	ENOG4105EUZ	Beta-lactamase domain protein
FRD49_13100	ENOG4105PGM	cation diffusion facilitator family transporter
FRD49_13115	ENOG4107Y80	Major Facilitator superfamily
FRD49_13220	ENOG4105DFP	Integrase
FRD49_13230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_13255	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
FRD49_13280	ENOG4108JQ5	ABC transporter
FRD49_13285	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
FRD49_13290	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
FRD49_13300	ENOG4105E9H	Lytic Murein transglycosylase
FRD49_13300	ENOG4105E9H	Lytic Murein transglycosylase
FRD49_13305	ENOG4108JDX	DNA polymerase iii, epsilon subunit
FRD49_13315	ENOG4105E09	nadh pyrophosphatase
FRD49_13325	ENOG4105W4M	Transport-associated protein
FRD49_13335	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FRD49_13340	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FRD49_13345	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
FRD49_13365	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FRD49_13370	ENOG4105D0A	hydroxylase
FRD49_13375	ENOG4107RAQ	aminopeptidase
FRD49_13410	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FRD49_13440	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FRD49_13450	ENOG4105D82	Glutamate dehydrogenase
FRD49_13455	ENOG4108R3D	Electron transport complex
FRD49_13460	ENOG4105CSM	endonuclease III
FRD49_13485	ENOG4105CJN	penicillin-binding protein
FRD49_13490	ENOG4106H78	methyltransferase
FRD49_13510	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
FRD49_13520	ENOG4105CQM	Urea amidohydrolase subunit alpha
FRD49_13555	ENOG4107RET	Isocitrate lyase
FRD49_13565	ENOG4105C37	(CBS) domain
FRD49_13570	ENOG4105D4T	Citrate transporter
FRD49_13585	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FRD49_13600	ENOG4108MRJ	
FRD49_13625	ENOG4105VCQ	rubredoxin
FRD49_13630	ENOG4107QZF	nitrite reductase NADPH large subunit
FRD49_13640	ENOG4105C5Q	Transcriptional regulator
FRD49_13660	ENOG4107U91	Rhomboid family
FRD49_13665	ENOG4105CV6	ABC transporter, permease
FRD49_13670	ENOG4108I0Y	(ABC) transporter
FRD49_13675	ENOG4108UJV	acyl-CoA thioesterase i
FRD49_13695	ENOG4107RNH	Outer membrane receptor FepA
FRD49_13710	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FRD49_13745	ENOG4105CJ3	phosphate transporter
FRD49_13755	ENOG4105C3R	Methionine synthase
FRD49_13765	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FRD49_13770	ENOG4105EU0	Major facilitator Superfamily
FRD49_13775	ENOG4105FTV	AraC Family Transcriptional Regulator
FRD49_13780	ENOG4105CSV	Glutaminase
FRD49_13785	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FRD49_13790	ENOG4105CSH	Transporter
FRD49_13800	ENOG4105C7K	acetolactate synthase
FRD49_13815	ENOG4105CHR	reductase
FRD49_13820	ENOG4108MXF	Alpha Beta Hydrolase
FRD49_13830	ENOG4105DJB	Major Facilitator Superfamily
FRD49_13835	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
FRD49_13845	ENOG4105CHR	reductase
FRD49_13865	ENOG41069M3	Transcriptional regulator
FRD49_13880	ENOG4106YT9	Enoyl-CoA hydratase
FRD49_13890	ENOG4105CND	Glycosyl transferase, family 2
FRD49_13895	ENOG4107BJW	polysaccharide deacetylase
FRD49_13905	ENOG4108VWS	Yaeq family
FRD49_13915	ENOG4105CKI	cobalamin synthesis protein
FRD49_13935	ENOG4105C94	Transporter
FRD49_13940	ENOG4105C94	Transporter
FRD49_13945	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
FRD49_13970	ENOG4107QK5	Homocysteine s-methyltransferase
FRD49_13975	ENOG4105D5Q	Arginine ornithine antiporter
FRD49_13995	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRD49_14000	ENOG4105C54	Major Facilitator superfamily
FRD49_14030	ENOG4105DZR	Type I site-specific deoxyribonuclease
FRD49_14035	ENOG4108HFV	
FRD49_14080	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FRD49_14085	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FRD49_14090	ENOG4105CW7	secretion protein, HlyD family
FRD49_14095	ENOG4108VUY	thioesterase Superfamily protein
FRD49_14100	ENOG4105D52	delta-aminolevulinic acid dehydratase
FRD49_14105	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FRD49_14110	ENOG4105ECP	epimerase
FRD49_14130	ENOG4107RH8	nuclease SbcCD subunit D
FRD49_14135	ENOG4105EYH	Exonuclease
FRD49_14140	ENOG4108QM7	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FRD49_14145	ENOG4105DFA	alanine racemase domain protein
FRD49_14150	ENOG4105CZX	twitching motility protein
FRD49_14155	ENOG4105CZX	twitching motility protein
FRD49_14160	ENOG41090R7	Ferric uptake
FRD49_14170	ENOG4105VDB	UPF0125 protein
FRD49_14190	ENOG4105E7A	Glutamine amidotransferase
FRD49_14205	ENOG4107QKV	phosphomannomutase
FRD49_14215	ENOG4105C4R	Atp-dependent dna helicase
FRD49_14220	ENOG4108ZG0	Ompa motb domain protein
FRD49_14225	ENOG4106HNH	Acyl-transferase
FRD49_14240	ENOG4107QMS	site-determining protein
FRD49_14260	ENOG4105CNU	cell division protein FtsK
FRD49_14265	ENOG4105C3M	thioredoxin reductase
FRD49_14270	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FRD49_14280	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FRD49_14310	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FRD49_14325	ENOG4108YXA	Membrane
FRD49_14330	ENOG4105EUB	pirin domain protein
FRD49_14340	ENOG4105C4K	Nad synthetase
FRD49_14355	ENOG4105E3J	oxidoreductase
FRD49_14360	ENOG4105C26	Dehydrogenase
FRD49_14365	ENOG4105DVW	rieske (2Fe-2S)
FRD49_14375	ENOG4105C94	Transporter
FRD49_14380	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FRD49_14385	ENOG4105EJC	lysr family transcriptional regulator
FRD49_14405	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FRD49_14425	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FRD49_14430	ENOG4105C34	Pseudouridine synthase
FRD49_14435	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRD49_14440	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FRD49_14455	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
FRD49_14485	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FRD49_14525	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FRD49_14535	ENOG4105DWF	phosphomethylpyrimidine kinase
FRD49_14540	ENOG4109066	lysm domain bon superfamily protein
FRD49_14550	ENOG4105CHR	reductase
FRD49_14555	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FRD49_14565	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
FRD49_14570	ENOG4108BPE	-transporting atpase
FRD49_14575	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FRD49_14580	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FRD49_14585	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FRD49_14590	ENOG4105FE9	pseudouridine synthase
FRD49_14600	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FRD49_14605	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FRD49_14615	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FRD49_14620	ENOG4108K4C	ec 3.1.3.12
FRD49_14625	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
FRD49_14630	ENOG4106UW1	Major Facilitator superfamily
FRD49_14650	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FRD49_14660	ENOG4105HF0	Membrane
FRD49_14675	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FRD49_14685	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
FRD49_14740	ENOG4105D1F	ATP-binding protein
FRD49_14755	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FRD49_14790	ENOG4105K6H	D-cysteine desulfhydrase
FRD49_14795	ENOG4105CBX	hi0933 family
FRD49_14820	ENOG4105DP0	ferredoxin-NADP reductase
FRD49_14825	ENOG4105DUM	transcriptional regulator, lysR family
FRD49_14850	ENOG4105C8S	subunit m
FRD49_14855	ENOG4105D65	subunit l
FRD49_14865	ENOG4107UFS	subunit j
FRD49_14880	ENOG4108IEH	NADH dehydrogenase subunit g
FRD49_14885	ENOG4107QIZ	NADH dehydrogenase
FRD49_14890	ENOG4105GKE	subunit e
FRD49_14910	ENOG4105BZU	Histidine kinase
FRD49_14920	ENOG4105E0F	Histidine kinase
FRD49_14925	ENOG4107EXC	regulatoR
FRD49_14935	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FRD49_14945	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FRD49_14955	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FRD49_15005	ENOG41082JN	Transcriptional regulator
FRD49_15015	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
FRD49_15020	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FRD49_15030	ENOG4105ETT	transcriptional Regulator, LysR family
FRD49_15040	ENOG4106P55	Transcriptional regulator
FRD49_15060	ENOG4106P55	Transcriptional regulator
FRD49_15065	ENOG4107EFR	Flavocytochrome c
FRD49_15090	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
FRD49_15095	ENOG4107RGD	Major Facilitator superfamily
FRD49_15100	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_15105	ENOG4105ETT	transcriptional Regulator, LysR family
FRD49_15140	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FRD49_15145	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FRD49_15150	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FRD49_15170	ENOG4105E3B	Multicopper oxidase
FRD49_15180	ENOG4108HCJ	Hydrolase
FRD49_15185	ENOG4105DJV	ribulose-phosphate 3-epimerase
FRD49_15210	ENOG41072GX	Peptidase M22 Glycoprotease
FRD49_15215	ENOG4108Z0R	Transferase
FRD49_15260	ENOG4105CRQ	synthase (Component I)
FRD49_15270	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FRD49_15275	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FRD49_15280	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FRD49_15350	ENOG4105K56	Transcriptional regulator
FRD49_15355	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FRD49_15360	ENOG4107QHF	type ii secretion system protein e
FRD49_15380	ENOG4105C2M	dna polymerase I
FRD49_15385	ENOG4108VIA	integral membrane protein
FRD49_15390	ENOG4105II7	pyrroline-5-carboxylate reductase
FRD49_15395	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FRD49_15405	ENOG4105C9X	ppx gppa phosphatase
FRD49_15415	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FRD49_15435	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FRD49_15460	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FRD49_15465	ENOG41082NX	50s ribosomal protein l35
FRD49_15485	ENOG4105W39	Membrane
FRD49_15490	ENOG4105CYM	Glutathione S-transferase
FRD49_15505	ENOG4105CEY	Amp-dependent synthetase and ligase
FRD49_15510	ENOG4105N42	UPF0307 protein
FRD49_15515	ENOG41080Z8	PHOSPHOCARRIER protein
FRD49_15535	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FRD49_15540	ENOG4105DJ0	Poly(A) Polymerase
FRD49_15545	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
FRD49_15550	ENOG4105DXN	mazG family
FRD49_15560	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FRD49_15575	ENOG4105C6T	cysteine synthase
FRD49_15580	ENOG4105BZU	Histidine kinase
FRD49_15585	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
FRD49_15590	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FRD49_15595	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
FRD49_15610	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FRD49_15615	ENOG4105W8H	transhydrogenase (subunit alpha
FRD49_15620	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FRD49_15625	ENOG4106UX7	integral membrane protein
FRD49_15655	ENOG4105E3B	Multicopper oxidase
FRD49_15670	ENOG4105GR3	Histidine kinase
FRD49_15760	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FRD49_15780	ENOG4105CUZ	uba thif-type nad fad binding protein
FRD49_15785	ENOG4107QM5	aconitate hydratase
FRD49_15790	ENOG4105F8V	Hydrolase, tatD family
FRD49_15805	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FRD49_15825	ENOG4105BZU	Histidine kinase
FRD49_15835	ENOG4108ZP8	Acetolactate synthase small subunit
FRD49_15840	ENOG4105C7K	acetolactate synthase
FRD49_15865	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FRD49_15870	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRD49_15875	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FRD49_15880	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FRD49_15890	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FRD49_15895	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FRD49_15905	ENOG4105VW4	glutaredoxin 3
FRD49_15925	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FRD49_15945	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
FRD49_15965	ENOG4105WVQ	Fe-S assembly protein IscX
FRD49_15980	ENOG4105CN1	protease
FRD49_15995	ENOG4106HB6	Alpha beta hydrolase
FRD49_16005	ENOG4105C26	Dehydrogenase
FRD49_16010	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FRD49_16015	ENOG4105C6Z	Gluconate
FRD49_16020	ENOG4108UHU	Aldolase
FRD49_16025	ENOG4105C01	Dihydroxy-acid dehydratase
FRD49_16030	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FRD49_16035	ENOG4108DNC	Involved in acetate metabolism (By similarity)
FRD49_16040	ENOG4107GFK	fumarate
FRD49_16060	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FRD49_16070	ENOG4108ESX	Receptor
FRD49_16080	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FRD49_16090	ENOG4105DWV	Homoserine O-trans-acetylase
FRD49_16180	ENOG4105SG9	biopolymer transport protein, ExbD
FRD49_16195	ENOG4105CIY	formyltetrahydrofolate deformylase
FRD49_16205	ENOG4107RGH	Aldehyde dehydrogenase
FRD49_16210	ENOG4105KDC	50s ribosomal protein l28
FRD49_16215	ENOG4105W0E	50S ribosomal protein L33
FRD49_16220	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FRD49_16240	ENOG4105VFU	Rna-binding protein
FRD49_16245	ENOG4105C4R	Atp-dependent dna helicase
FRD49_16260	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FRD49_16270	ENOG4105KVH	Transcriptional regulator
FRD49_16280	ENOG41069P5	Protein slyX homolog
FRD49_16285	ENOG4105C5H	ABC transporter
FRD49_16295	ENOG4105N14	lysine exporter protein LysE YggA
FRD49_16300	ENOG4105D1S	lipid A biosynthesis
FRD49_16310	ENOG4105CK2	sodium dicarboxylate symporter
FRD49_16365	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FRD49_16420	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
FRD49_16435	ENOG4108W5M	transcriptional regulator
FRD49_16450	ENOG4105D29	Helix-turn-helix type 11 domain protein
FRD49_16460	ENOG4105EI2	Pseudouridine synthase
FRD49_16470	ENOG4105C03	ribonuclease
FRD49_16490	ENOG4105CBN	LysR family transcriptional regulator
FRD49_16500	ENOG4105CSA	Coproporphyrinogen iii oxidase
FRD49_16510	ENOG4107QI1	Mate efflux family protein
FRD49_16520	ENOG4107T8P	acyl-Coa dehydrogenase
FRD49_16560	ENOG4105BZ8	glutamate synthase
FRD49_16570	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FRD49_16575	ENOG4105C5X	domain protein
FRD49_16590	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FRD49_16600	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FRD49_16610	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FRD49_16615	ENOG4108JU5	Magnesium and cobalt efflux protein
FRD49_16620	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FRD49_16625	ENOG4108Z7R	Chaperone CsaA
FRD49_16640	ENOG4108VAU	general secretion pathway protein G
FRD49_16645	ENOG4105D7Q	type ii secretion system
FRD49_16650	ENOG4105C25	Primosomal protein n'
FRD49_16655	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FRD49_16660	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FRD49_16670	ENOG4105DVC	DnaJ domain protein
FRD49_16675	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
FRD49_16680	ENOG4107QUT	magnesium and cobalt transport protein CorA
FRD49_16685	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FRD49_16700	ENOG4107QYX	exodeoxyribonuclease v alpha
FRD49_16705	ENOG4107QKA	exodeoxyribonuclease V beta
FRD49_16710	ENOG4105DSY	exodeoxyribonuclease V, gamma
FRD49_16725	ENOG4105CSR	polyphosphate kinase 2
FRD49_16735	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FRD49_16745	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FRD49_16755	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FRD49_16760	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FRD49_16775	ENOG4105D65	subunit l
FRD49_16780	ENOG4108ZE9	Monovalent cation H antiporter subunit C
FRD49_16785	ENOG4107R4Z	monovalent cation h antiporter subunit d
FRD49_16790	ENOG4105SC1	monovalent cation H antiporter subunit E
FRD49_16795	ENOG4105W4C	monovalent cation H antiporter subunit F
FRD49_16800	ENOG4105KJM	monovalent cation h antiporter subunit g
FRD49_16805	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FRD49_16815	ENOG4105CHV	Transcription elongation factor NusA
FRD49_16840	ENOG4107EJC	Preprotein translocase subunit SecG
FRD49_16850	ENOG4107QHF	type ii secretion system protein e
FRD49_16865	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FRD49_16875	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FRD49_16890	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FRD49_16900	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FRD49_16915	ENOG4105DSW	Fusaric acid resistance protein
FRD49_16930	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FRD49_16935	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FRD49_16985	ENOG4105MJ9	esterase
FRD49_16990	ENOG4108Z6Z	Transcriptional regulator
FRD49_17000	ENOG4107ZXU	DSBA oxidoreductase
FRD49_17015	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FRD49_17030	ENOG4105D3Y	Na H antiporter
FRD49_17035	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FRD49_17090	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FRD49_17095	ENOG4105PM1	preprotein translocase subunit SecE
FRD49_17135	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FRD49_17140	ENOG4105TV9	FHA Domain-Containing protein
FRD49_17145	ENOG4105GVR	general secretion pathway protein D
FRD49_17160	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
FRD49_17185	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FRD49_17190	ENOG4108NEV	two component transcriptional regulator, LytTR family
FRD49_17195	ENOG4108HRK	Histidine kinase
FRD49_17210	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FRD49_17215	ENOG4105DFG	type I secretion outer membrane protein
FRD49_17245	ENOG41087AY	ADP-Ribose pyrophosphatase
FRD49_17250	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FRD49_17255	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FRD49_17260	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FRD49_17265	ENOG4105CNI	cell division protein FtsW
FRD49_17280	ENOG4105CE1	Ferrous iron transport protein b
FRD49_17290	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FRD49_17295	ENOG4105T95	Thiol disulfide interChange protein
FRD49_17300	ENOG4105D6E	homoserine dehydrogenase
FRD49_17310	ENOG41061WM	D-Alanyl-D-Alanine
FRD49_17320	ENOG4107TUY	Histidine kinase
FRD49_17325	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FRD49_17330	ENOG4105CN1	protease
FRD49_17335	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FRD49_17340	ENOG4108K5H	permease YjgP YjgQ family protein
FRD49_17380	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FRD49_17390	ENOG4105BZU	Histidine kinase
FRD49_17405	ENOG4105C0P	Mg chelatase subunit ChlI
FRD49_17410	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FRD49_17415	ENOG4105FB2	class II Aldolase
FRD49_17420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRD49_17430	ENOG4105EPF	Outer membrane porin
FRD49_17435	ENOG4105F0N	pyrophosphate phospho-hydrolase
FRD49_17450	ENOG4105CEY	Amp-dependent synthetase and ligase
FRD49_17455	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRD49_17460	ENOG41079KZ	Major Facilitator Superfamily
FRD49_17465	ENOG4105EN6	Membrane
FRD49_17470	ENOG4105K5B	UPF0225 protein
FRD49_17475	ENOG4105EE5	Membrane protein terC
FRD49_17480	ENOG4108URH	decarboxylase
FRD49_17485	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FRD49_17495	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FRD49_17510	ENOG4105CCT	upf0313 protein
FRD49_17530	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FRD49_17545	ENOG4105C6T	cysteine synthase
FRD49_17580	ENOG4105Y7M	Transcriptional regulator, TetR family
FRD49_17615	ENOG4105C79	DNA protecting protein DprA
FRD49_17630	ENOG4108IND	Tetr family transcriptional regulator
FRD49_17635	ENOG4107RTG	Major Facilitator superfamily
FRD49_17645	ENOG4108V06	Glutathione peroxidase
FRD49_17655	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FRD49_17685	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FRD49_17710	ENOG4105FDK	ABC transporter
FRD49_17715	ENOG4105FAV	ABC, transporter
FRD49_17725	ENOG4105EZR	dyp-type peroxidase family protein
FRD49_17730	ENOG4107R1I	NAD-dependent malic enzyme
FRD49_17755	ENOG4105EUB	pirin domain protein
FRD49_17770	ENOG4108428	Inherit from COG: -acetyltransferase
FRD49_17775	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FRD49_17780	ENOG4106MP8	UPF0754 membrane protein
FRD49_17785	ENOG4108VBZ	doxx family
FRD49_17790	ENOG4105DQR	SNARE associated Golgi
FRD49_17805	ENOG4107QJE	Chromosome Partitioning Protein
FRD49_17815	ENOG4107PSF	BolA-like protein
FRD49_17860	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_17865	ENOG4107RCI	amp-dependent synthetase and ligase
FRD49_17885	ENOG4105CSH	Transporter
FRD49_17890	ENOG4105E39	Enoyl-CoA hydratase
FRD49_17895	ENOG4105E39	Enoyl-CoA hydratase
FRD49_17900	ENOG4105C1G	acyl-Coa dehydrogenase
FRD49_17910	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FRD49_17915	ENOG4105C26	Dehydrogenase
FRD49_17925	ENOG4105C85	amino acid
FRD49_17930	ENOG4105C85	amino acid
FRD49_17935	ENOG4105M4H	endoribonuclease L-psp
FRD49_17950	ENOG4105EW9	transcriptional regulator AsnC family
FRD49_17975	ENOG4105D3G	Pseudouridine synthase
FRD49_18040	ENOG4108I0Z	Aconitate hydratase
FRD49_18045	ENOG4105BZN	citrate synthase
FRD49_18050	ENOG4105CR4	methylisocitrate lyase
FRD49_18055	ENOG4105DRR	Transcriptional regulator, GntR family
FRD49_18065	ENOG4105CGF	Aromatic amino acid aminotransferase
FRD49_18070	ENOG4105CXG	d-lactate dehydrogenase
FRD49_18080	ENOG41073TP	transcriptional regulator
FRD49_18085	ENOG4105DAA	L-lactate
FRD49_18090	ENOG4107QKV	phosphomannomutase
FRD49_18105	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FRD49_18120	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FRD49_18125	ENOG4105D3Q	Sugar transferase
FRD49_18150	ENOG41090RK	glycosyl transferase
FRD49_18170	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FRD49_18175	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FRD49_18180	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FRD49_18185	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FRD49_18190	ENOG4107QQG	Dehydrogenase
FRD49_18195	ENOG4105DAY	polysaccharide export protein
FRD49_18205	ENOG4105D75	Capsular exopolysaccharide family
FRD49_18210	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FRD49_18215	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FRD49_18220	ENOG4105CJR	Integral membrane protein (MviN
FRD49_18225	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
FRD49_18230	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FRD49_18240	ENOG4105HSS	phospholipase C
FRD49_18265	ENOG41062JF	Transcriptional regulator
FRD49_18280	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FRD49_18285	ENOG4105UBK	short-chain dehydrogenase reductase
FRD49_18300	ENOG4107QZM	n-acetylglutamate synthase
FRD49_18305	ENOG4105GVF	(ABC) transporter
FRD49_18310	ENOG4105GVF	(ABC) transporter
FRD49_18315	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
FRD49_18320	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
FRD49_18325	ENOG4108VM9	ABC, transporter
FRD49_18330	ENOG4108R86	Transcriptional regulator
FRD49_18335	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FRD49_18345	ENOG4105DTN	riboflavin biosynthesis protein ribF
FRD49_18350	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FRD49_18360	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FRD49_18400	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FRD49_18455	ENOG4105CVE	Lytic murein transglycosylase
FRD49_18460	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FRD49_18465	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FRD49_18480	ENOG4105DFU	Cell wall formation (By similarity)
FRD49_18490	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
FRD49_18495	ENOG4105DU1	integral membrane protein, terc
FRD49_18505	ENOG4106032	Glutathionylspermidine synthase
FRD49_18515	ENOG4107QUY	Guanine deaminase
FRD49_18520	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FRD49_18530	ENOG4105T95	Thiol disulfide interChange protein
FRD49_18535	ENOG4105PGM	cation diffusion facilitator family transporter
FRD49_18550	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FRD49_18565	ENOG4105VG0	50S ribosomal protein l34
FRD49_18610	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
FRD49_18620	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FRD49_18650	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
FRD49_18705	ENOG4105EMU	Dehydrogenase
FRD49_18710	ENOG410810E	transcriptional regulator, lysR family
FRD49_18715	ENOG4107QPD	alcohol dehydrogenase
FRD49_18720	ENOG4108JA1	polyketide synthase
FRD49_18730	ENOG4105RPH	Inner membrane protein YddG
FRD49_18735	ENOG4105CSH	Transporter
FRD49_18745	ENOG4105ECQ	AraC Family Transcriptional Regulator
FRD49_18765	ENOG4105C4W	S-formylglutathione hydrolase
FRD49_18780	ENOG4108I6A	alcohol dehydrogenase
FRD49_18790	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRD49_18800	ENOG4108WUH	Transcriptional regulator, TetR family
FRD49_18805	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FRD49_18815	ENOG41066UD	Inhibits activity of g-type lysozyme, which confers increased lysozyme tolerance to the bacterium
FRD49_18855	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FRD49_18885	ENOG4105D0M	Protease HtpX homolog
FRD49_18920	ENOG4105EQ2	LysR family Transcriptional regulator
FRD49_18930	ENOG4105DQ4	alcohol dehydrogenase
FRD49_18935	ENOG4107RTG	Major Facilitator superfamily
FRD49_18945	ENOG4105ENX	hydrolase
FRD49_18985	ENOG4107QJE	Chromosome Partitioning Protein
FRD49_19010	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family